Motif ID: NANOG.p2

Z-value: 1.282


Transcription factors associated with NANOG.p2:

Gene SymbolEntrez IDGene Name
NANOG 79923 Nanog homeobox

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NANOGchr12_+_79419940.338.8e-07Click!


Activity profile for motif NANOG.p2.

activity profile for motif NANOG.p2


Sorted Z-values histogram for motif NANOG.p2

Sorted Z-values for motif NANOG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NANOG.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_16760935 14.527 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr6_-_32497925 12.800 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr15_+_58430394 10.602 NM_020980
AQP9
aquaporin 9
chr7_-_37025696 10.178 ELMO1
engulfment and cell motility 1
chr12_-_16759939 9.399 NM_001243613
LMO3
LIM domain only 3 (rhombotin-like 2)
chrX_+_103031753 9.390 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr12_-_16759733 8.318 NM_001243610
LMO3
LIM domain only 3 (rhombotin-like 2)
chr7_-_25268057 8.058 NM_022150
NPVF
neuropeptide VF precursor
chrX_+_103031797 7.946 PLP1
proteolipid protein 1
chr18_+_21572736 7.630 NM_153211
TTC39C
tetratricopeptide repeat domain 39C
chr16_+_6823809 7.354 NM_001142334
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr4_-_176734181 6.997 NM_201591
GPM6A
glycoprotein M6A
chr12_+_25205488 6.243 LRMP
lymphoid-restricted membrane protein
chr4_+_71587674 6.124 NM_001037442
NM_014961
RUFY3

RUN and FYVE domain containing 3

chr4_+_113970784 6.090 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr3_-_12941547 6.001 IQSEC1
IQ motif and Sec7 domain 1
chr3_+_115342302 5.998 GAP43
growth associated protein 43
chr13_-_95131718 5.837 NM_001129889
NM_001922
DCT

dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)

chr10_+_11206928 5.803 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr6_-_32557431 5.792 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr2_+_226265601 5.743 NM_020864
NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr1_+_198608136 5.634 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr4_-_174451356 5.631 NM_021973
HAND2
heart and neural crest derivatives expressed 2
chr1_+_198608216 5.559 PTPRC
protein tyrosine phosphatase, receptor type, C
chr12_+_25205180 5.518 NM_001204126
NM_001204127
NM_006152
LRMP


lymphoid-restricted membrane protein


chr7_-_14025826 5.474 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr3_+_115342150 5.474 NM_001130064
NM_002045
GAP43

growth associated protein 43

chr6_-_31107110 5.407 NM_014069
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr5_-_88179278 5.386 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr2_+_162272892 5.333 TBR1
T-box, brain, 1
chr12_-_52779362 5.323 NM_033045
KRT84
keratin 84
chr12_-_52828105 5.275 NM_004693
KRT75
keratin 75
chr3_+_35722428 5.207 NM_198399
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr2_-_224467095 5.194 SCG2
secretogranin II
chr19_+_7968701 5.159 MAP2K7
mitogen-activated protein kinase kinase 7
chr10_-_13749622 5.154 FRMD4A
FERM domain containing 4A
chr12_-_15114495 5.125 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr4_-_186578122 5.095 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr10_-_52645384 5.031 A1CF
APOBEC1 complementation factor
chr5_-_112630301 4.951 MCC
mutated in colorectal cancers
chr1_+_209878135 4.907 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr11_-_57195052 4.893 NM_017611
SLC43A3
solute carrier family 43, member 3
chr1_-_150738232 4.855 CTSS
cathepsin S
chr14_+_101295409 4.763 MEG3
maternally expressed 3 (non-protein coding)
chr2_-_217724781 4.730 NM_003284
TNP1
transition protein 1 (during histone to protamine replacement)
chr16_+_6533758 4.538 RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr6_+_50786438 4.477 NM_003221
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr12_-_6233684 4.449 NM_000552
VWF
von Willebrand factor
chr14_+_92789536 4.428 NM_153647
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr10_+_11207053 4.427 CELF2
CUGBP, Elav-like family member 2
chr15_+_89631731 4.400 ABHD2
abhydrolase domain containing 2
chr3_+_35721115 4.389 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr12_-_4488707 4.377 NM_020638
FGF23
fibroblast growth factor 23
chr3_+_111717585 4.360 NM_001008272
NM_013259
TAGLN3

transgelin 3

chr16_-_21314371 4.328 NM_001014444
NM_001888
CRYM

crystallin, mu

chr15_+_89631695 4.298 ABHD2
abhydrolase domain containing 2
chr12_+_51318743 4.254 METTL7A
methyltransferase like 7A
chr2_-_224467049 4.239 SCG2
secretogranin II
chr19_+_45409003 4.198 NM_000041
APOE
apolipoprotein E
chr20_+_36932551 4.197 NM_001725
BPI
bactericidal/permeability-increasing protein
chr3_+_129247481 4.190 NM_000539
RHO
rhodopsin
chr1_+_50574601 4.174 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr1_+_50575465 4.172 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr17_-_10421858 4.118 NM_005963
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr3_+_152880036 4.055 RAP2B
RAP2B, member of RAS oncogene family
chr19_+_45971249 4.051 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr5_-_112630557 3.889 NM_002387
MCC
mutated in colorectal cancers
chr11_-_128712340 3.866 NM_000220
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr15_+_89631625 3.865 ABHD2
abhydrolase domain containing 2
chr3_+_69985750 3.864 NM_000248
NM_001184968
NM_198158
NM_198178
MITF



microphthalmia-associated transcription factor



chr10_+_35416384 3.849 NM_181571
NM_183060
CREM

cAMP responsive element modulator

chr2_+_210444154 3.843 MAP2
microtubule-associated protein 2
chr1_+_151739130 3.812 NM_016178
OAZ3
ornithine decarboxylase antizyme 3
chr4_-_176733901 3.797 GPM6A
glycoprotein M6A
chr4_-_57547845 3.562 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr14_-_60097314 3.561 RTN1
reticulon 1
chr12_+_8276227 3.530 NM_016184
NM_194447
NM_194448
NM_194450
CLEC4A



C-type lectin domain family 4, member A



chrX_+_28605558 3.525 NM_014271
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr9_+_120466453 3.513 NM_138554
TLR4
toll-like receptor 4
chr14_+_35514112 3.464 NM_001079519
FAM177A1
family with sequence similarity 177, member A1
chr4_-_80329354 3.463 NM_033214
GK2
glycerol kinase 2
chr13_+_102104941 3.437 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr1_+_6105980 3.402 NM_001199862
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr9_+_120466625 3.354 TLR4
toll-like receptor 4
chr14_+_92788924 3.309 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr6_+_32407618 3.309 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr3_+_121796695 3.287 NM_006889
NM_176892
CD86

CD86 molecule

chr8_-_40755328 3.250 NM_001135731
NM_024645
ZMAT4

zinc finger, matrin-type 4

chr8_+_24298442 3.234 NM_003817
ADAM7
ADAM metallopeptidase domain 7
chr12_+_51318515 3.158 NM_014033
METTL7A
methyltransferase like 7A
chr2_-_224467142 3.156 NM_003469
SCG2
secretogranin II
chr2_+_162272619 3.145 NM_006593
TBR1
T-box, brain, 1
chr20_+_30697291 3.136 NM_014742
TM9SF4
transmembrane 9 superfamily protein member 4
chr11_-_83393436 3.119 NM_001142702
DLG2
discs, large homolog 2 (Drosophila)
chr12_-_16757944 3.115 LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_-_121379757 3.096 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr11_-_102595623 3.076 NM_002424
MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
chr20_+_2276612 3.051 NM_003245
TGM3
transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr5_-_149466173 3.047 CSF1R
colony stimulating factor 1 receptor
chr18_+_32173281 3.045 NM_001128175
NM_001198938
NM_001198939
NM_001198940
DTNA



dystrobrevin, alpha



chrX_-_137821514 3.039 NM_033642
FGF13
fibroblast growth factor 13
chr6_+_32605182 3.017 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr7_-_137028533 3.016 NM_002825
PTN
pleiotrophin
chr5_+_140809957 3.007 PCDHGA12
protocadherin gamma subfamily A, 12
chr2_+_162272800 2.998 TBR1
T-box, brain, 1
chr16_+_8814567 2.943 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr5_-_140013034 2.915 NM_000591
CD14
CD14 molecule
chr2_+_169757749 2.909 NM_001081686
NM_021176
G6PC2

glucose-6-phosphatase, catalytic, 2

chr9_-_5339745 2.894 NM_006911
RLN1
relaxin 1
chr9_+_82187469 2.891 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr21_-_39956823 2.888 NM_001243429
ERG
v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr7_+_39017608 2.862 NM_001166018
NM_007252
POU6F2

POU class 6 homeobox 2

chr9_+_82187599 2.837 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr11_-_117748200 2.837 NM_001164831
FXYD6
FXYD domain containing ion transport regulator 6
chr6_-_26189303 2.834 NM_003539
HIST1H4D
histone cluster 1, H4d
chr3_-_121379701 2.795 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_+_156119734 2.792 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr21_-_31538970 2.763 NM_012131
CLDN17
claudin 17
chr19_-_45826232 2.727 NM_001824
CKM
creatine kinase, muscle
chr2_+_210444364 2.727 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr5_+_170736287 2.719 NM_021025
TLX3
T-cell leukemia homeobox 3
chr12_-_24103953 2.695 SOX5
SRY (sex determining region Y)-box 5
chr11_+_818836 2.693 NM_020376
PNPLA2
patatin-like phospholipase domain containing 2
chr2_-_166930130 2.667 NM_001165963
NM_001165964
NM_006920
SCN1A


sodium channel, voltage-gated, type I, alpha subunit


chr10_+_49609641 2.661 NM_002750
NM_139046
NM_139047
NM_139049
MAPK8



mitogen-activated protein kinase 8



chr12_-_102874299 2.658 IGF1
insulin-like growth factor 1 (somatomedin C)
chr7_-_115670774 2.657 TFEC
transcription factor EC
chr12_-_16759531 2.648 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr7_-_14029641 2.643 NM_001163147
NM_004956
ETV1

ets variant 1

chr15_-_55563091 2.633 NM_183236
RAB27A
RAB27A, member RAS oncogene family
chr5_-_149466126 2.575 CSF1R
colony stimulating factor 1 receptor
chr1_+_101003692 2.569 NM_022049
GPR88
G protein-coupled receptor 88
chr5_-_88199868 2.568 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr11_+_88911039 2.482 NM_000372
TYR
tyrosinase (oculocutaneous albinism IA)
chr7_+_23286386 2.429 GPNMB
glycoprotein (transmembrane) nmb
chr11_-_72145343 2.427 NM_030813
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chrX_+_103031433 2.425 NM_001128834
PLP1
proteolipid protein 1
chr2_-_209010876 2.404 NM_005210
CRYGB
crystallin, gamma B
chr8_-_27115935 2.397 STMN4
stathmin-like 4
chr12_-_110252600 2.375 NM_001177431
NM_001177428
NM_001177433
NM_147204
TRPV4



transient receptor potential cation channel, subfamily V, member 4



chr5_-_42811959 2.356 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr14_+_23305816 2.351 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr1_-_154842725 2.350 NM_001204087
NM_002249
KCNN3

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

chr2_+_234959345 2.349 NM_006944
SPP2
secreted phosphoprotein 2, 24kDa
chr11_-_72145602 2.331 CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr6_-_42690308 2.326 NM_000322
PRPH2
peripherin 2 (retinal degeneration, slow)
chr8_-_87755880 2.325 NM_019098
CNGB3
cyclic nucleotide gated channel beta 3
chrX_+_110366304 2.303 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr19_+_7968765 2.298 MAP2K7
mitogen-activated protein kinase kinase 7
chr4_-_26491888 2.295 NM_000730
CCKAR
cholecystokinin A receptor
chr3_-_69171536 2.293 NM_198271
LMOD3
leiomodin 3 (fetal)
chr11_+_7618416 2.292 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr7_+_129015483 2.267 NM_001130722
AHCYL2
adenosylhomocysteinase-like 2
chr12_-_109027654 2.262 NM_003006
SELPLG
selectin P ligand
chr4_-_87281374 2.262 NM_138980
NM_138982
MAPK10

mitogen-activated protein kinase 10

chr6_+_131894343 2.260 NM_000045
NM_001244438
ARG1

arginase, liver

chr2_-_65593763 2.255 SPRED2
sprouty-related, EVH1 domain containing 2
chr12_-_16759430 2.245 LMO3
LIM domain only 3 (rhombotin-like 2)
chrX_+_66788682 2.243 NM_001011645
AR
androgen receptor
chr8_-_27101240 2.237 STMN4
stathmin-like 4
chr17_-_10452939 2.237 NM_001100112
NM_017534
MYH2

myosin, heavy chain 2, skeletal muscle, adult

chr12_+_81110689 2.224 NM_005593
MYF5
myogenic factor 5
chr3_-_101039403 2.209 NM_016247
IMPG2
interphotoreceptor matrix proteoglycan 2
chr15_+_67841341 2.207 NM_001206804
MAP2K5
mitogen-activated protein kinase kinase 5
chr7_-_115670828 2.206 NM_001018058
NM_012252
TFEC

transcription factor EC

chr3_-_57234279 2.203 NM_003865
HESX1
HESX homeobox 1
chr17_-_9929567 2.198 NM_001130831
GAS7
growth arrest-specific 7
chr3_+_89156804 2.196 EPHA3
EPH receptor A3
chr17_+_41052813 2.183 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr1_+_50574589 2.180 NM_001144774
NM_021952
ELAVL4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

chr22_+_40573879 2.173 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr18_-_3874688 2.171 NM_001242762
NM_001242763
DLGAP1

discs, large (Drosophila) homolog-associated protein 1

chr17_-_79105747 2.169 NM_004920
AATK
apoptosis-associated tyrosine kinase
chr10_-_52645430 2.164 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr12_-_102874373 2.157 NM_000618
NM_001111283
NM_001111285
IGF1


insulin-like growth factor 1 (somatomedin C)


chr12_-_4554779 2.156 NM_020996
FGF6
fibroblast growth factor 6
chr3_-_39321479 2.149 NM_001337
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr8_-_67090690 2.123 NM_000756
CRH
corticotropin releasing hormone
chr5_+_176853673 2.110 NM_001004105
NM_001004106
NM_002082
GRK6


G protein-coupled receptor kinase 6


chr8_+_32579350 2.110 NM_001159996
NRG1
neuregulin 1
chr19_+_54641475 2.107 CNOT3
CCR4-NOT transcription complex, subunit 3
chr6_-_32634287 2.081 NM_001243961
NM_002123
HLA-DQB1

major histocompatibility complex, class II, DQ beta 1

chr1_+_50569581 2.073 NM_001144776
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr18_-_31803514 2.072 NM_001198546
NM_001198548
NM_003787
NOL4


nucleolar protein 4


chr18_-_31803168 2.065 NOL4
nucleolar protein 4
chr19_+_7968764 2.063 NM_145185
MAP2K7
mitogen-activated protein kinase kinase 7
chr16_+_10522724 2.061 NM_024997
ATF7IP2
activating transcription factor 7 interacting protein 2
chr7_+_18535817 2.049 NM_058176
NM_178425
HDAC9

histone deacetylase 9

chr13_-_41593491 2.046 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr10_+_18549583 2.035 NM_000724
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr9_+_12693385 2.035 NM_000550
TYRP1
tyrosinase-related protein 1
chr11_+_58390145 2.022 NM_000614
CNTF
ciliary neurotrophic factor
chr13_-_41593405 2.014 ELF1
E74-like factor 1 (ets domain transcription factor)
chr17_+_4854383 1.994 NM_001193503
NM_001976
NM_053013
ENO3


enolase 3 (beta, muscle)


chr12_-_91398744 1.983 EPYC
epiphycan
chr6_-_136847609 1.958 MAP7
microtubule-associated protein 7
chr4_-_8873453 1.954 NM_018942
HMX1
H6 family homeobox 1
chr3_+_69812961 1.950 NM_006722
MITF
microphthalmia-associated transcription factor
chr11_-_117747618 1.948 NM_001204268
NM_001243598
NM_001164832
NM_001164836
NM_001164837
NM_022003
FXYD6-FXYD2

FXYD6



FXYD6-FXYD2 readthrough

FXYD domain containing ion transport regulator 6



chr14_-_21270537 1.943 NM_198232
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.66 5.36e-18 GO:0032501 multicellular organismal process
1.79 2.24e-13 GO:0007275 multicellular organismal development
1.73 6.29e-13 GO:0032502 developmental process
1.82 3.37e-11 GO:0048731 system development
1.76 6.96e-11 GO:0048856 anatomical structure development
1.62 5.00e-09 GO:0023052 signaling
1.92 4.84e-07 GO:0003008 system process
1.86 6.38e-07 GO:0048513 organ development
1.37 1.52e-06 GO:0050896 response to stimulus
1.50 1.59e-06 GO:0051716 cellular response to stimulus
1.30 1.62e-06 GO:0065007 biological regulation
2.54 1.83e-06 GO:0045595 regulation of cell differentiation
1.56 5.23e-06 GO:0007165 signal transduction
1.31 7.25e-06 GO:0050789 regulation of biological process
2.20 2.15e-05 GO:0050793 regulation of developmental process
1.74 2.21e-05 GO:0030154 cell differentiation
1.89 2.64e-05 GO:0007399 nervous system development
2.32 2.99e-05 GO:0007267 cell-cell signaling
1.69 9.19e-05 GO:0048869 cellular developmental process
2.05 1.51e-04 GO:0007154 cell communication
1.29 2.39e-04 GO:0050794 regulation of cellular process
1.72 3.36e-04 GO:0007166 cell surface receptor linked signaling pathway
2.21 3.43e-04 GO:2000026 regulation of multicellular organismal development
2.52 3.45e-04 GO:0007417 central nervous system development
1.88 3.77e-04 GO:0051239 regulation of multicellular organismal process
1.51 2.92e-03 GO:0048518 positive regulation of biological process
2.99 3.42e-03 GO:0045596 negative regulation of cell differentiation
2.75 4.07e-03 GO:0051093 negative regulation of developmental process
2.41 4.13e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.18 6.93e-03 GO:0045893 positive regulation of transcription, DNA-dependent
3.85 7.47e-03 GO:0001503 ossification
1.53 7.85e-03 GO:0048519 negative regulation of biological process
6.87 8.32e-03 GO:0051149 positive regulation of muscle cell differentiation
2.11 8.71e-03 GO:0010628 positive regulation of gene expression
1.73 9.39e-03 GO:0050877 neurological system process
2.02 1.21e-02 GO:0006955 immune response
1.95 1.26e-02 GO:0009891 positive regulation of biosynthetic process
3.01 1.35e-02 GO:0007601 visual perception
3.01 1.35e-02 GO:0050953 sensory perception of light stimulus
1.94 1.72e-02 GO:0031328 positive regulation of cellular biosynthetic process
2.00 1.93e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.14 1.99e-02 GO:0009987 cellular process
2.57 2.11e-02 GO:0044057 regulation of system process
2.32 2.57e-02 GO:0051094 positive regulation of developmental process
1.90 2.58e-02 GO:0006351 transcription, DNA-dependent
1.84 2.59e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.52 3.29e-02 GO:0048523 negative regulation of cellular process
2.03 3.64e-02 GO:0051254 positive regulation of RNA metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.62 1.59e-04 GO:0005576 extracellular region
1.74 1.21e-02 GO:0044421 extracellular region part
10.91 1.44e-02 GO:0042613 MHC class II protein complex
15.27 1.78e-02 GO:0033162 melanosome membrane
15.27 1.78e-02 GO:0045009 chitosome
1.45 2.26e-02 GO:0044459 plasma membrane part
1.61 3.97e-02 GO:0005887 integral to plasma membrane
1.29 4.94e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.17 9.19e-07 GO:0001071 nucleic acid binding transcription factor activity
2.17 9.19e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
2.23 9.62e-05 GO:0043565 sequence-specific DNA binding
3.27 7.53e-03 GO:0008083 growth factor activity
1.76 1.31e-02 GO:0005102 receptor binding