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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: NHLH1,2.p2

Z-value: 2.609

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_35521591	41.904	NM_001037 NM_199037	SCN1B	sodium channel, voltage-gated, type I, beta
chr8_+_24771276	39.890		NEFM	neurofilament, medium polypeptide
chr8_+_24771268	34.605	NM_005382	NEFM	neurofilament, medium polypeptide
chr18_-_74691951	32.843		MBP	myelin basic protein
chr3_-_195306274	32.155		APOD	apolipoprotein D
chrX_-_13956530	27.148		GPM6B	glycoprotein M6B
chr14_+_100150596	26.922	NM_006668	CYP46A1	cytochrome P450, family 46, subfamily A, polypeptide 1
chr11_-_125366048	26.908	NM_005103 NM_022549	FEZ1	fasciculation and elongation protein zeta 1 (zygin I)
chr1_+_233749749	26.867	NM_002245	KCNK1	potassium channel, subfamily K, member 1
chr20_-_23618382	26.616	NM_000099	CST3	cystatin C
chr2_+_233498206	25.247	NM_025202	EFHD1	EF-hand domain family, member D1
chr6_-_159420796	25.087		RSPH3	radial spoke 3 homolog (Chlamydomonas)
chr14_-_103988829	24.141		CKB	creatine kinase, brain
chrX_-_13956644	24.096	NM_001001994	GPM6B	glycoprotein M6B
chr3_-_149688886	24.059		PFN2	profilin 2
chr16_-_57318574	23.868	NM_015993	PLLP	plasmolipin
chr1_+_77747727	23.352		AK5	adenylate kinase 5
chrX_-_13956445	23.210
chr20_+_10199455	22.741	NM_003081 NM_130811	SNAP25	synaptosomal-associated protein, 25kDa
chr16_+_58497628	22.700		NDRG4	NDRG family member 4
chrX_+_47092362	22.001		USP11	ubiquitin specific peptidase 11
chr2_+_79740059	21.854	NM_001164883 NM_004389	CTNNA2	catenin (cadherin-associated protein), alpha 2
chrX_+_47092264	21.851	NM_004651	USP11	ubiquitin specific peptidase 11
chr10_-_73611041	21.789		PSAP	prosaposin
chr6_-_84419108	21.728	NM_001242793 NM_001242794 NM_014841	SNAP91	synaptosomal-associated protein, 91kDa homolog (mouse)
chr12_+_79258517	21.484		SYT1	synaptotagmin I
chr6_-_84419018	21.346		SNAP91	synaptosomal-associated protein, 91kDa homolog (mouse)
chr16_+_50099907	21.247		HEATR3	HEAT repeat containing 3
chr10_+_104678001	21.160	NM_017649 NM_199076 NM_199077	CNNM2	cyclin M2
chr6_+_126112057	21.121		NCOA7	nuclear receptor coactivator 7
chr16_+_58497548	21.089	NM_020465	NDRG4	NDRG family member 4
chr19_-_6502224	21.086	NM_006087	TUBB4A	tubulin, beta 4A class IVa
chr17_+_7554415	21.032		ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide
chr7_-_137531585	20.971	NM_004717	DGKI	diacylglycerol kinase, iota
chr1_+_171810611	20.918	NM_001136127 NM_015569	DNM3	dynamin 3
chr12_+_79258588	20.663		SYT1	synaptotagmin I
chr10_-_73611005	20.511		PSAP	prosaposin
chr16_+_330605	19.905	NM_001176	ARHGDIG	Rho GDP dissociation inhibitor (GDI) gamma
chr8_+_85095452	19.669	NM_001100392 NM_001100393	RALYL	RALY RNA binding protein-like
chr1_+_233749917	18.702		KCNK1	potassium channel, subfamily K, member 1
chr1_-_57045129	18.471		PPAP2B	phosphatidic acid phosphatase type 2B
chr22_+_29876180	18.229	NM_021076	NEFH	neurofilament, heavy polypeptide
chr19_+_4304590	18.215	NM_024333	FSD1	fibronectin type III and SPRY domain containing 1
chr13_-_45150391	18.100		TSC22D1	TSC22 domain family, member 1
chr3_-_73673978	18.076	NM_015009	PDZRN3	PDZ domain containing ring finger 3
chr20_-_3154169	17.927		ProSAPiP1	ProSAPiP1 protein
chr10_-_81205091	17.820	NM_153367	ZCCHC24	zinc finger, CCHC domain containing 24
chr7_+_139877154	17.624		LOC100134229	uncharacterized LOC100134229
chr2_+_79740171	17.585		CTNNA2	catenin (cadherin-associated protein), alpha 2
chr16_+_1756161	17.486	NM_001040439 NM_015133	MAPK8IP3	mitogen-activated protein kinase 8 interacting protein 3
chr11_-_75141015	17.418		KLHL35	kelch-like 35 (Drosophila)
chr6_-_84418705	17.406	NM_001242792	SNAP91	synaptosomal-associated protein, 91kDa homolog (mouse)
chr17_-_15165860	17.302		PMP22	peripheral myelin protein 22
chr10_+_124220990	17.280	NM_002775	HTRA1	HtrA serine peptidase 1
chr3_+_167453431	17.245	NM_001122752 NM_005025	SERPINI1	serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr2_+_149633173	17.059
chr10_-_73610958	16.921		PSAP	prosaposin
chr6_-_46459010	16.551	NM_001251974	RCAN2	regulator of calcineurin 2
chr19_-_49944613	16.321	NM_020309	SLC17A7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr3_-_42305438	16.222	NM_001174138	CCK	cholecystokinin
chr19_-_58609606	16.126	NM_001145543 NM_001145544 NM_023926	ZSCAN18	zinc finger and SCAN domain containing 18
chr1_+_46269283	15.948	NM_015112	MAST2	microtubule associated serine/threonine kinase 2
chr10_+_105036783	15.934	NM_032727	INA	internexin neuronal intermediate filament protein, alpha
chr17_-_79139871	15.842	NM_001080395	AATK	apoptosis-associated tyrosine kinase
chr12_-_50297575	15.717	NM_012306	FAIM2	Fas apoptotic inhibitory molecule 2
chr16_-_57318452	15.480		PLLP	plasmolipin
chr11_-_66335958	15.350	NM_003793	CTSF	cathepsin F
chr11_+_113930430	15.315	NM_006006	ZBTB16	zinc finger and BTB domain containing 16
chr5_+_113698304	15.280		KCNN2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr6_+_43543921	15.195		POLH	polymerase (DNA directed), eta
chr5_-_136834887	15.111	NM_004598	SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr16_+_23847271	15.040	NM_002738 NM_212535	PRKCB	protein kinase C, beta
chr3_-_120068077	14.846	NM_001099678	LRRC58	leucine rich repeat containing 58
chr14_+_93389444	14.831	NM_001275	CHGA	chromogranin A (parathyroid secretory protein 1)
chr16_+_23847321	14.767		PRKCB	protein kinase C, beta
chr12_+_79258448	14.715	NM_005639	SYT1	synaptotagmin I
chr12_+_79258794	14.682		SYT1	synaptotagmin I
chr8_+_136469557	14.478	NM_006558	KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3
chrX_-_47479229	14.386	NM_006950 NM_133499	SYN1	synapsin I
chr8_-_145669796	14.372	NM_013432	TONSL	tonsoku-like, DNA repair protein
chr19_-_46974663	14.369		PNMAL1	PNMA-like 1
chr3_-_62861012	14.294	NM_003716 NM_183393 NM_183394	CADPS	Ca++-dependent secretion activator
chr19_+_3094528	14.261		GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr10_-_73611050	14.208	NM_001042465 NM_001042466 NM_002778	PSAP	prosaposin
chr4_-_57976550	14.197	NM_001253835 NM_001553	IGFBP7	insulin-like growth factor binding protein 7
chr2_-_47797469	14.089	NM_022055	KCNK12	potassium channel, subfamily K, member 12
chr1_-_57044980	14.086		PPAP2B	phosphatidic acid phosphatase type 2B
chr19_+_36359346	14.026	NM_001024807 NM_005166	APLP1	amyloid beta (A4) precursor-like protein 1
chr17_+_36507708	13.968	NM_014598	SOCS7	suppressor of cytokine signaling 7
chr13_-_36705432	13.853		DCLK1	doublecortin-like kinase 1
chr4_+_7045142	13.732	NM_152293	TADA2B	transcriptional adaptor 2B
chr3_-_149688638	13.661	NM_002628 NM_053024	PFN2	profilin 2
chr14_-_21493858	13.507		NDRG2	NDRG family member 2
chr16_+_22825806	13.474	NM_006043	HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr16_+_23847359	13.341		PRKCB	protein kinase C, beta
chr1_-_57045214	13.299		PPAP2B	phosphatidic acid phosphatase type 2B
chr10_-_135150474	13.250	NM_015722	CALY	calcyon neuron-specific vesicular protein
chr19_-_46974789	13.236	NM_001103149 NM_018215	PNMAL1	PNMA-like 1
chr19_+_13875345	13.189		MRI1	methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)
chr6_-_29600668	13.159		GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr7_+_45614081	13.087	NM_021116	ADCY1	adenylate cyclase 1 (brain)
chr2_+_191745791	13.057		GLS	glutaminase
chr19_+_12949258	12.987	NM_014975	MAST1	microtubule associated serine/threonine kinase 1
chr1_+_202317798	12.916	NM_001167857 NM_001167858 NM_002481	PPP1R12B	protein phosphatase 1, regulatory subunit 12B
chr7_+_29234325	12.893		CHN2	chimerin (chimaerin) 2
chr1_+_20959946	12.877	NM_032409	PINK1	PTEN induced putative kinase 1
chr18_-_5543967	12.859	NM_012307	EPB41L3	erythrocyte membrane protein band 4.1-like 3
chr7_-_124405029	12.757		GPR37	G protein-coupled receptor 37 (endothelin receptor type B-like)
chr1_-_32229635	12.675	NM_001703	BAI2	brain-specific angiogenesis inhibitor 2
chr1_+_77747602	12.590	NM_174858	AK5	adenylate kinase 5
chr19_-_18314731	12.487	NM_002866	RAB3A	RAB3A, member RAS oncogene family
chr12_+_53443834	12.464	NM_170754	TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr17_-_27278324	12.462		PHF12	PHD finger protein 12
chr18_-_74729049	12.401	NM_001025081 NM_001025090 NM_001025092 NM_002385	MBP	myelin basic protein
chrX_-_48693934	12.334	NM_013271	PCSK1N	proprotein convertase subtilisin/kexin type 1 inhibitor
chr14_+_90863302	12.307	NM_006888	CALM1	calmodulin 1 (phosphorylase kinase, delta)
chr14_+_90863365	12.303		CALM1	calmodulin 1 (phosphorylase kinase, delta)
chr12_-_124457099	12.255	NM_025140	CCDC92	coiled-coil domain containing 92
chr17_-_56609387	12.179	NM_080415 NM_080416	SEPT4	septin 4
chr10_-_135150368	12.031		CALY	calcyon neuron-specific vesicular protein
chr4_-_57976516	12.028		IGFBP7	insulin-like growth factor binding protein 7
chr11_-_35547144	11.963	NM_001001991 NM_015430	PAMR1	peptidase domain containing associated with muscle regeneration 1
chr8_+_85095501	11.921	NM_173848	RALYL	RALY RNA binding protein-like
chr14_+_76127592	11.910		TTLL5	tubulin tyrosine ligase-like family, member 5
chr5_+_151151660	11.757		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr2_+_236403290	11.724		AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr8_+_24772454	11.628	NM_001105541	NEFM	neurofilament, medium polypeptide
chr2_+_236402948	11.622		AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr5_+_67511578	11.543	NM_181523	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr16_+_22825481	11.514		HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr2_-_55277459	11.437		RTN4	reticulon 4
chr13_-_36705513	11.433	NM_004734	DCLK1	doublecortin-like kinase 1
chr2_-_55277698	11.306	NM_020532 NM_153828 NM_207520	RTN4	reticulon 4
chr7_+_98246595	11.292	NM_002523	NPTX2	neuronal pentraxin II
chr19_+_18723666	11.286	NM_012109	TMEM59L	transmembrane protein 59-like
chrX_+_135229536	11.281	NM_001159702 NM_001159703 NM_001449	FHL1	four and a half LIM domains 1
chr11_-_6440631	11.258	NM_145689	APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr4_-_5890142	11.171		CRMP1	collapsin response mediator protein 1
chr10_-_15413054	11.162	NM_001010924	FAM171A1	family with sequence similarity 171, member A1
chr14_+_93389491	11.147		CHGA	chromogranin A (parathyroid secretory protein 1)
chrX_-_140271275	11.118		LDOC1	leucine zipper, down-regulated in cancer 1
chr15_+_74833517	11.020	NM_006465	ARID3B	AT rich interactive domain 3B (BRIGHT-like)
chr14_+_29236882	10.989		FOXG1	forkhead box G1
chr12_-_120554558	10.961		RAB35	RAB35, member RAS oncogene family
chr7_-_766875	10.943	NM_001164760	PRKAR1B	protein kinase, cAMP-dependent, regulatory, type I, beta
chr11_-_78128765	10.938		GAB2	GRB2-associated binding protein 2
chr5_+_139493689	10.931	NM_005859	PURA	purine-rich element binding protein A
chr11_-_207324	10.842		BET1L	blocked early in transport 1 homolog (S. cerevisiae)-like
chr4_+_176987148	10.828		WDR17	WD repeat domain 17
chr3_+_184056304	10.696		FAM131A	family with sequence similarity 131, member A
chr1_-_40157067	10.671	NM_016257	HPCAL4	hippocalcin like 4
chr9_+_17134974	10.663	NM_001114395 NM_017738	CNTLN	centlein, centrosomal protein
chr19_-_19006868	10.610	NM_021267 NM_198207 NM_001492	CERS1 GDF1	ceramide synthase 1 growth differentiation factor 1
chr9_+_124030455	10.494		GSN	gelsolin
chr11_+_113930296	10.373		ZBTB16	zinc finger and BTB domain containing 16
chr20_+_20348744	10.338	NM_002196	INSM1	insulinoma-associated 1
chr22_-_18923654	10.292		PRODH	proline dehydrogenase (oxidase) 1
chr10_-_133795447	10.273		BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3
chr22_+_32340592	10.257		YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr15_+_75118950	10.248	NM_001030005	CPLX3	complexin 3
chr16_+_3355432	10.239	NM_153028	ZNF75A	zinc finger protein 75a
chr5_-_73936299	10.183		ENC1	ectodermal-neural cortex 1 (with BTB-like domain)
chrX_+_53111482	10.173	NM_022117	TSPYL2	TSPY-like 2
chr7_-_149321828	10.163		ZNF767	zinc finger family member 767
chr6_-_29600859	10.137		GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr21_+_27011588	10.132	NM_021219	JAM2	junctional adhesion molecule 2
chr11_-_207391	10.080		BET1L	blocked early in transport 1 homolog (S. cerevisiae)-like
chr18_+_21594349	10.025	NM_001135993 NM_001243425	TTC39C	tetratricopeptide repeat domain 39C
chr3_-_195310985	9.982	NM_001647	APOD	apolipoprotein D
chr18_-_74728963	9.980		MBP	myelin basic protein
chr6_-_167040700	9.948	NM_021135	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr7_-_158622184	9.831		ESYT2	extended synaptotagmin-like protein 2
chr4_-_5890266	9.790	NM_001313	CRMP1	collapsin response mediator protein 1
chr20_+_19193364	9.740		SLC24A3	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr1_-_21995793	9.736	NM_001145657 NM_002885	RAP1GAP	RAP1 GTPase activating protein
chr17_-_56609361	9.703		SEPT4	septin 4
chr16_+_31085751	9.703		ZNF646	zinc finger protein 646
chr3_-_45267068	9.645		TMEM158	transmembrane protein 158 (gene/pseudogene)
chr8_+_22462532	9.578	NM_021174	KIAA1967	KIAA1967
chr12_-_120554453	9.576		RAB35	RAB35, member RAS oncogene family
chr8_-_145669771	9.522		TONSL	tonsoku-like, DNA repair protein
chr17_+_47653474	9.484		NXPH3	neurexophilin 3
chr16_+_31085722	9.469	NM_014699	ZNF646	zinc finger protein 646
chr1_+_51701995	9.453		RNF11	ring finger protein 11
chr2_+_149632772	9.408	NM_004522	KIF5C	kinesin family member 5C
chrX_-_40506666	9.406		CXorf38	chromosome X open reading frame 38
chr3_-_133614421	9.395	NM_016577	RAB6B	RAB6B, member RAS oncogene family
chr17_+_28256873	9.349	NM_001145053	EFCAB5	EF-hand calcium binding domain 5
chr10_-_118764559	9.322		KIAA1598	KIAA1598
chr19_+_45409003	9.282	NM_000041	APOE	apolipoprotein E
chr17_-_15165873	9.282	NM_153321	PMP22	peripheral myelin protein 22
chr7_-_108166514	9.260		PNPLA8	patatin-like phospholipase domain containing 8
chr5_-_178772430	9.257	NM_014244 NM_021599	ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr1_+_2005083	9.238	NM_001033581	PRKCZ	protein kinase C, zeta
chr11_-_117747331	9.226		FXYD6	FXYD domain containing ion transport regulator 6
chr6_-_29600959	9.142	NM_001470 NM_021904	GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr7_-_44530178	9.141	NM_015332	NUDCD3	NudC domain containing 3
chr9_-_139940595	9.133	NM_015392	NPDC1	neural proliferation, differentiation and control, 1
chr10_+_105037441	9.110		INA	internexin neuronal intermediate filament protein, alpha
chr19_+_13875299	9.088	NM_001031727 NM_032285	MRI1	methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.68	7.18e-27	GO:0007399	nervous system development
1.43	8.05e-27	GO:0048856	anatomical structure development
1.38	5.12e-26	GO:0023052	signaling
1.45	8.74e-26	GO:0048731	system development
1.37	5.11e-25	GO:0032502	developmental process
1.39	9.89e-25	GO:0007275	multicellular organismal development
1.21	3.83e-23	GO:0065007	biological regulation
1.36	4.02e-20	GO:0007165	signal transduction
1.20	6.75e-18	GO:0050794	regulation of cellular process
1.19	6.99e-18	GO:0050789	regulation of biological process
1.12	3.99e-17	GO:0009987	cellular process
1.53	1.99e-16	GO:0009653	anatomical structure morphogenesis
1.24	4.67e-16	GO:0032501	multicellular organismal process
1.28	1.45e-15	GO:0051716	cellular response to stimulus
1.43	2.20e-15	GO:0048869	cellular developmental process
1.70	4.60e-15	GO:0048699	generation of neurons
1.42	1.03e-14	GO:0030154	cell differentiation
1.53	2.37e-14	GO:0035556	intracellular signal transduction
1.66	2.39e-14	GO:0022008	neurogenesis
1.65	3.82e-14	GO:0048468	cell development
1.75	6.35e-14	GO:0030182	neuron differentiation
1.44	1.80e-13	GO:0007166	cell surface receptor linked signaling pathway
1.81	6.61e-13	GO:0048666	neuron development
1.86	7.60e-11	GO:0048667	cell morphogenesis involved in neuron differentiation
1.81	1.09e-10	GO:0031175	neuron projection development
1.47	1.42e-10	GO:0051239	regulation of multicellular organismal process
1.85	1.50e-10	GO:0048812	neuron projection morphogenesis
1.35	2.46e-10	GO:0065008	regulation of biological quality
1.86	2.60e-10	GO:0007409	axonogenesis
1.78	3.01e-10	GO:0007417	central nervous system development
1.79	3.02e-10	GO:0000904	cell morphogenesis involved in differentiation
1.69	3.40e-10	GO:0030030	cell projection organization
1.34	5.05e-10	GO:0042221	response to chemical stimulus
1.77	5.51e-10	GO:0048858	cell projection morphogenesis
1.37	5.73e-10	GO:0048513	organ development
1.76	1.21e-09	GO:0032990	cell part morphogenesis
1.56	2.68e-09	GO:0040011	locomotion
1.76	2.71e-09	GO:0019226	transmission of nerve impulse
1.76	2.71e-09	GO:0035637	multicellular organismal signaling
1.59	5.51e-09	GO:0007267	cell-cell signaling
1.39	6.11e-09	GO:0023051	regulation of signaling
1.67	6.47e-09	GO:0000902	cell morphogenesis
1.78	1.15e-08	GO:0007268	synaptic transmission
1.64	1.24e-08	GO:0032989	cellular component morphogenesis
1.62	1.45e-08	GO:0009719	response to endogenous stimulus
1.95	1.84e-08	GO:0019932	second-messenger-mediated signaling
1.49	2.06e-08	GO:0007154	cell communication
2.66	2.61e-08	GO:0007202	activation of phospholipase C activity
1.79	3.17e-08	GO:0016477	cell migration
2.63	4.16e-08	GO:0010863	positive regulation of phospholipase C activity
1.24	4.34e-08	GO:0051179	localization
2.32	4.42e-08	GO:0019935	cyclic-nucleotide-mediated signaling
2.58	6.11e-08	GO:0010518	positive regulation of phospholipase activity
1.50	1.08e-07	GO:0050793	regulation of developmental process
1.16	1.13e-07	GO:0050896	response to stimulus
2.51	1.33e-07	GO:0010517	regulation of phospholipase activity
1.61	2.48e-07	GO:0009725	response to hormone stimulus
1.84	2.70e-07	GO:0007411	axon guidance
1.47	3.09e-07	GO:0009605	response to external stimulus
1.54	4.60e-07	GO:2000026	regulation of multicellular organismal development
2.46	5.10e-07	GO:0019933	cAMP-mediated signaling
1.69	8.69e-07	GO:0048870	cell motility
1.69	8.69e-07	GO:0051674	localization of cell
2.42	1.13e-06	GO:0060193	positive regulation of lipase activity
1.56	1.60e-06	GO:0007167	enzyme linked receptor protein signaling pathway
1.61	1.78e-06	GO:0006928	cellular component movement
2.26	2.07e-06	GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger
2.49	2.98e-06	GO:0045761	regulation of adenylate cyclase activity
1.27	3.12e-06	GO:0048519	negative regulation of biological process
1.65	3.90e-06	GO:0072358	cardiovascular system development
1.65	3.90e-06	GO:0072359	circulatory system development
1.77	4.79e-06	GO:0044057	regulation of system process
2.44	6.70e-06	GO:0031279	regulation of cyclase activity
2.23	7.77e-06	GO:0060191	regulation of lipase activity
1.30	8.31e-06	GO:0048583	regulation of response to stimulus
1.28	8.52e-06	GO:0048523	negative regulation of cellular process
1.43	9.02e-06	GO:0032879	regulation of localization
1.37	9.99e-06	GO:0010033	response to organic substance
1.35	1.38e-05	GO:0009966	regulation of signal transduction
2.39	1.45e-05	GO:0051339	regulation of lyase activity
2.30	1.98e-05	GO:0030817	regulation of cAMP biosynthetic process
1.77	2.38e-05	GO:0022603	regulation of anatomical structure morphogenesis
1.71	2.50e-05	GO:0007420	brain development
2.28	2.81e-05	GO:0030814	regulation of cAMP metabolic process
2.21	3.39e-05	GO:0030799	regulation of cyclic nucleotide metabolic process
2.36	3.52e-05	GO:0021700	developmental maturation
2.22	3.99e-05	GO:0030802	regulation of cyclic nucleotide biosynthetic process
2.22	3.99e-05	GO:0030808	regulation of nucleotide biosynthetic process
1.39	4.06e-05	GO:0010646	regulation of cell communication
1.44	4.20e-05	GO:0009888	tissue development
1.71	8.37e-05	GO:0043434	response to peptide hormone stimulus
2.33	8.42e-05	GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger
2.10	9.27e-05	GO:0031644	regulation of neurological system process
2.18	1.46e-04	GO:0050890	cognition
1.22	1.59e-04	GO:0048518	positive regulation of biological process
2.23	1.74e-04	GO:0007611	learning or memory
2.18	2.82e-04	GO:0050804	regulation of synaptic transmission
1.58	3.45e-04	GO:0051094	positive regulation of developmental process
2.10	4.11e-04	GO:0051969	regulation of transmission of nerve impulse
1.46	4.42e-04	GO:0045595	regulation of cell differentiation
1.72	4.44e-04	GO:0001944	vasculature development
1.52	7.92e-04	GO:0006935	chemotaxis
1.52	7.92e-04	GO:0042330	taxis
1.72	8.06e-04	GO:0061061	muscle structure development
1.50	9.28e-04	GO:0007186	G-protein coupled receptor protein signaling pathway
1.22	9.50e-04	GO:0048522	positive regulation of cellular process
4.00	9.96e-04	GO:0042551	neuron maturation
1.55	1.03e-03	GO:0048646	anatomical structure formation involved in morphogenesis
1.70	1.11e-03	GO:0051270	regulation of cellular component movement
1.88	1.13e-03	GO:0014070	response to organic cyclic compound
1.72	1.22e-03	GO:0001568	blood vessel development
1.59	1.29e-03	GO:0007264	small GTPase mediated signal transduction
1.51	1.40e-03	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.73	1.50e-03	GO:0030334	regulation of cell migration
1.65	1.55e-03	GO:0051093	negative regulation of developmental process
1.75	1.55e-03	GO:0050767	regulation of neurogenesis
2.44	1.65e-03	GO:0050770	regulation of axonogenesis
1.70	1.69e-03	GO:0051960	regulation of nervous system development
1.19	1.74e-03	GO:0051234	establishment of localization
2.71	1.79e-03	GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
1.68	1.92e-03	GO:0040012	regulation of locomotion
2.03	2.01e-03	GO:0043627	response to estrogen stimulus
1.46	2.28e-03	GO:0009887	organ morphogenesis
1.19	2.32e-03	GO:0006810	transport
1.71	2.60e-03	GO:2000145	regulation of cell motility
1.46	2.87e-03	GO:0042060	wound healing
1.35	3.07e-03	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.64	3.36e-03	GO:0007610	behavior
1.68	3.55e-03	GO:0048545	response to steroid hormone stimulus
1.46	4.25e-03	GO:0050878	regulation of body fluid levels
1.76	5.22e-03	GO:0048514	blood vessel morphogenesis
1.49	5.95e-03	GO:0007599	hemostasis
1.49	7.09e-03	GO:0007596	blood coagulation
1.49	7.09e-03	GO:0050817	coagulation
2.56	7.18e-03	GO:0048016	inositol phosphate-mediated signaling
1.17	7.79e-03	GO:0016043	cellular component organization
1.77	7.86e-03	GO:0045664	regulation of neuron differentiation
1.61	8.66e-03	GO:0060284	regulation of cell development
1.70	8.68e-03	GO:0007507	heart development
2.51	1.10e-02	GO:0031281	positive regulation of cyclase activity
2.51	1.10e-02	GO:0045762	positive regulation of adenylate cyclase activity
1.38	1.22e-02	GO:0006468	protein phosphorylation
1.55	1.30e-02	GO:0009792	embryo development ending in birth or egg hatching
2.40	1.30e-02	GO:0043279	response to alkaloid
1.81	1.42e-02	GO:0030900	forebrain development
1.35	1.47e-02	GO:0006351	transcription, DNA-dependent
1.50	1.71e-02	GO:0046903	secretion
1.54	1.79e-02	GO:0090066	regulation of anatomical structure size
1.70	1.91e-02	GO:0048011	nerve growth factor receptor signaling pathway
1.57	1.95e-02	GO:0071495	cellular response to endogenous stimulus
1.50	2.21e-02	GO:0007243	intracellular protein kinase cascade
1.50	2.21e-02	GO:0023014	signal transduction via phosphorylation event
1.40	2.24e-02	GO:0001932	regulation of protein phosphorylation
3.98	2.29e-02	GO:0043401	steroid hormone mediated signaling pathway
1.53	2.46e-02	GO:0043009	chordate embryonic development
2.42	2.49e-02	GO:0007194	negative regulation of adenylate cyclase activity
2.42	2.49e-02	GO:0031280	negative regulation of cyclase activity
2.42	2.49e-02	GO:0051349	positive regulation of lyase activity
2.42	2.49e-02	GO:0051350	negative regulation of lyase activity
1.61	2.71e-02	GO:0035295	tube development
2.46	2.81e-02	GO:0007190	activation of adenylate cyclase activity
1.95	3.04e-02	GO:0007265	Ras protein signal transduction
1.91	3.33e-02	GO:0001763	morphogenesis of a branching structure
1.33	3.43e-02	GO:0009611	response to wounding
1.58	3.65e-02	GO:0048729	tissue morphogenesis
1.67	3.83e-02	GO:0032868	response to insulin stimulus
2.16	3.88e-02	GO:0032355	response to estradiol stimulus
1.57	3.88e-02	GO:0032870	cellular response to hormone stimulus
3.13	3.92e-02	GO:0007632	visual behavior
2.22	3.99e-02	GO:0048469	cell maturation
1.37	4.08e-02	GO:0051049	regulation of transport
1.88	4.34e-02	GO:0042391	regulation of membrane potential
1.65	4.41e-02	GO:0030168	platelet activation
1.54	4.95e-02	GO:0032535	regulation of cellular component size

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.42	3.58e-17	GO:0044459	plasma membrane part
1.58	4.90e-17	GO:0005887	integral to plasma membrane
1.57	5.09e-17	GO:0031226	intrinsic to plasma membrane
1.12	1.03e-09	GO:0005737	cytoplasm
1.77	7.90e-09	GO:0043005	neuron projection
1.07	1.06e-06	GO:0044424	intracellular part
1.18	1.56e-06	GO:0005886	plasma membrane
2.01	3.08e-06	GO:0030424	axon
1.07	3.33e-06	GO:0005622	intracellular
1.43	3.58e-06	GO:0042995	cell projection
1.17	5.92e-06	GO:0071944	cell periphery
1.64	6.95e-06	GO:0045202	synapse
1.42	4.73e-05	GO:0031982	vesicle
1.92	7.75e-05	GO:0043025	neuronal cell body
1.89	1.01e-04	GO:0044297	cell body
1.55	4.28e-04	GO:0044463	cell projection part
1.39	5.44e-04	GO:0031988	membrane-bounded vesicle
1.79	7.23e-04	GO:0030425	dendrite
1.37	1.06e-03	GO:0031410	cytoplasmic vesicle
1.53	1.70e-03	GO:0031012	extracellular matrix
1.30	2.13e-03	GO:0000267	cell fraction
1.34	3.04e-03	GO:0005626	insoluble fraction
1.37	3.48e-03	GO:0016023	cytoplasmic membrane-bounded vesicle
1.39	7.38e-03	GO:0030054	cell junction
2.14	8.66e-03	GO:0033267	axon part
1.33	8.87e-03	GO:0005624	membrane fraction
1.10	1.85e-02	GO:0044444	cytoplasmic part
1.53	2.03e-02	GO:0044456	synapse part
3.26	2.54e-02	GO:0044304	main axon

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.16	9.87e-13	GO:0005515	protein binding
1.09	1.31e-12	GO:0005488	binding
1.36	1.84e-04	GO:0001071	nucleic acid binding transcription factor activity
1.36	1.84e-04	GO:0003700	sequence-specific DNA binding transcription factor activity
1.91	4.18e-04	GO:0005085	guanyl-nucleotide exchange factor activity
1.51	4.92e-04	GO:0060589	nucleoside-triphosphatase regulator activity
1.52	5.73e-04	GO:0030695	GTPase regulator activity
1.50	2.01e-03	GO:0019904	protein domain specific binding
1.38	2.52e-03	GO:0015075	ion transmembrane transporter activity
1.22	3.14e-03	GO:0032553	ribonucleotide binding
1.22	3.14e-03	GO:0032555	purine ribonucleotide binding
1.37	3.15e-03	GO:0042802	identical protein binding
1.22	3.16e-03	GO:0017076	purine nucleotide binding
1.31	3.61e-03	GO:0022892	substrate-specific transporter activity
1.43	3.86e-03	GO:0008324	cation transmembrane transporter activity
1.38	7.20e-03	GO:0043565	sequence-specific DNA binding
1.60	9.76e-03	GO:0032403	protein complex binding
1.21	1.03e-02	GO:0035639	purine ribonucleoside triphosphate binding
1.48	1.37e-02	GO:0005216	ion channel activity
1.32	1.40e-02	GO:0022891	substrate-specific transmembrane transporter activity
1.47	1.40e-02	GO:0015267	channel activity
1.47	1.58e-02	GO:0022803	passive transmembrane transporter activity
1.47	1.65e-02	GO:0022838	substrate-specific channel activity
1.30	1.79e-02	GO:0022857	transmembrane transporter activity
1.23	2.47e-02	GO:0030554	adenyl nucleotide binding
1.22	2.76e-02	GO:0032559	adenyl ribonucleotide binding
1.80	2.82e-02	GO:0005516	calmodulin binding
1.56	2.85e-02	GO:0005261	cation channel activity
2.64	3.17e-02	GO:0008227	G-protein coupled amine receptor activity
2.91	3.46e-02	GO:0017046	peptide hormone binding
1.52	3.86e-02	GO:0022836	gated channel activity
2.34	4.54e-02	GO:0003707	steroid hormone receptor activity
1.38	4.80e-02	GO:0008092	cytoskeletal protein binding