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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: NKX3-2.p2

Z-value: 2.020

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_+_118604417	28.923	NM_001077654	TNFAIP8	tumor necrosis factor, alpha-induced protein 8
chr5_+_118604504	27.750		TNFAIP8	tumor necrosis factor, alpha-induced protein 8
chr16_-_88717395	22.537	NM_000101	CYBA	cytochrome b-245, alpha polypeptide
chr14_-_107179043	21.679		IGHA1	immunoglobulin heavy constant alpha 1
chr6_-_32497925	20.051	NM_002125	HLA-DRB5	major histocompatibility complex, class II, DR beta 5
chr13_+_31287614	16.859	NM_001204406	ALOX5AP	arachidonate 5-lipoxygenase-activating protein
chr5_-_149792370	16.442	NM_001025158 NM_001025159 NM_004355	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chrX_-_47518539	15.608	NM_004182 NM_153477	UXT	ubiquitously-expressed, prefoldin-like chaperone
chr3_+_69134057	14.757	NM_006407	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5
chr7_-_26232148	14.448		HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1
chr16_-_28222700	13.727		XPO6	exportin 6
chr6_+_32407618	13.457	NM_019111	HLA-DRA	major histocompatibility complex, class II, DR alpha
chr20_-_34330093	13.183		RBM39	RNA binding motif protein 39
chr16_-_4896197	13.049		GLYR1	glyoxylate reductase 1 homolog (Arabidopsis)
chr13_+_31309644	13.018	NM_001629	ALOX5AP	arachidonate 5-lipoxygenase-activating protein
chr1_-_31230594	12.997		LAPTM5	lysosomal protein transmembrane 5
chr6_+_29974352	12.922		HLA-J	major histocompatibility complex, class I, J (pseudogene)
chr10_-_75193297	12.686	NM_001024593	ZMYND17	zinc finger, MYND-type containing 17
chr10_+_11047253	12.484	NM_001025077	CELF2	CUGBP, Elav-like family member 2
chr6_-_31550065	12.154	NM_002341 NM_009588	LTB	lymphotoxin beta (TNF superfamily, member 3)
chrX_-_47518487	12.009		UXT	ubiquitously-expressed, prefoldin-like chaperone
chr6_-_86352650	11.984		SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr1_-_111743261	11.453	NM_024901	DENND2D	DENN/MADD domain containing 2D
chr12_-_46662709	11.423		SLC38A1	solute carrier family 38, member 1
chr14_-_106471439	11.041		IGHA1 IGHG1 IGHM	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr4_-_83351294	11.026	NM_001207000 NM_031372	HNRPDL	heterogeneous nuclear ribonucleoprotein D-like
chr1_-_153363544	11.018	NM_002964	S100A8	S100 calcium binding protein A8
chr3_-_121379757	10.902	NM_005335	HCLS1	hematopoietic cell-specific Lyn substrate 1
chr6_-_32557431	10.831	NM_001243965 NM_002124	HLA-DRB1 HLA-DRB4 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 4 major histocompatibility complex, class II, DR beta 5
chr6_+_29855506	10.755
chr20_-_34330179	10.710	NM_001242599 NM_001242600 NM_004902 NM_184234	RBM39	RNA binding motif protein 39
chr17_-_38721701	10.682	NM_001838	CCR7	chemokine (C-C motif) receptor 7
chr20_-_34330177	10.660		RBM39	RNA binding motif protein 39
chr12_-_46662779	10.624		SLC38A1	solute carrier family 38, member 1
chr11_+_117857123	10.611		IL10RA	interleukin 10 receptor, alpha
chr8_+_123793894	10.557	NM_014943	ZHX2	zinc fingers and homeoboxes 2
chr3_-_121379701	10.512		HCLS1	hematopoietic cell-specific Lyn substrate 1
chr11_+_60223281	10.491	NM_021950 NM_152866	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr5_-_150467220	10.489	NM_001252390	TNIP1	TNFAIP3 interacting protein 1
chr8_+_123793988	10.473		ZHX2	zinc fingers and homeoboxes 2
chr11_+_117857062	10.297	NM_001558	IL10RA	interleukin 10 receptor, alpha
chr8_+_123794043	10.193		ZHX2	zinc fingers and homeoboxes 2
chr5_-_149792276	10.151		CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr6_-_31324898	10.145		HLA-B	major histocompatibility complex, class I, B
chr11_-_102323353	10.068	NM_052932	TMEM123	transmembrane protein 123
chr10_+_11047274	10.045		CELF2	CUGBP, Elav-like family member 2
chr13_-_46756295	9.866		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr12_-_92539614	9.776	NM_001731	BTG1	B-cell translocation gene 1, anti-proliferative
chr16_+_30075530	9.762	NM_184043	ALDOA	aldolase A, fructose-bisphosphate
chr13_-_46756326	9.728	NM_002298	LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr6_-_31324955	9.655		HLA-B	major histocompatibility complex, class I, B
chr16_-_11680756	9.634	NM_001136472 NM_001136473	LITAF	lipopolysaccharide-induced TNF factor
chr2_+_85804613	9.580	NM_003761	VAMP8	vesicle-associated membrane protein 8 (endobrevin)
chr1_+_26606212	9.496	NM_031286	SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3
chr19_+_41284068	9.379	NM_016154	RAB4B	RAB4B, member RAS oncogene family
chr16_+_30075440	9.204		ALDOA	aldolase A, fructose-bisphosphate
chr5_-_150466696	9.199	NM_001252391 NM_001252392	TNIP1	TNFAIP3 interacting protein 1
chr1_+_40735749	9.185		ZMPSTE24	zinc metallopeptidase (STE24 homolog, S. cerevisiae)
chr6_-_30712294	9.155	NM_003897	IER3	immediate early response 3
chr1_-_111743297	9.133		DENND2D	DENN/MADD domain containing 2D
chrX_+_131157635	9.090	NM_001042452	MST4	serine/threonine protein kinase MST4
chr2_+_219081864	9.006	NM_152862	ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa
chr3_-_146262421	8.982	NM_021105	PLSCR1	phospholipid scramblase 1
chr3_-_81810618	8.902		GBE1	glucan (1,4-alpha-), branching enzyme 1
chr11_-_111249902	8.900		POU2AF1	POU class 2 associating factor 1
chr6_-_31324975	8.812	NM_005514	HLA-B	major histocompatibility complex, class I, B
chr8_-_117768032	8.790		EIF3H	eukaryotic translation initiation factor 3, subunit H
chr3_-_146262320	8.788		PLSCR1	phospholipid scramblase 1
chr1_+_26644458	8.607		CD52	CD52 molecule
chr1_-_25256767	8.591	NM_004350	RUNX3	runt-related transcription factor 3
chr2_+_219082119	8.556	NM_005731	ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa
chr17_-_29648631	8.452	NM_001003927 NM_014210	EVI2A	ecotropic viral integration site 2A
chr2_+_85804724	8.438		VAMP8	vesicle-associated membrane protein 8 (endobrevin)
chr14_-_106733392	8.252		IGHG1 IGHG3	immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr2_+_219081914	8.202		ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa
chr10_+_11060105	8.161		CELF2	CUGBP, Elav-like family member 2
chr1_-_225616556	7.975	NM_194442	LBR	lamin B receptor
chr6_-_86352564	7.959	NM_001159674 NM_001253771	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr17_-_4851688	7.922		PFN1	profilin 1
chr18_-_51690988	7.918		MBD2	methyl-CpG binding domain protein 2
chr1_-_25291474	7.830	NM_001031680	RUNX3	runt-related transcription factor 3
chr7_-_102212967	7.789		POLR2J2 POLR2J3	polymerase (RNA) II (DNA directed) polypeptide J2 polymerase (RNA) II (DNA directed) polypeptide J3
chr2_-_152146373	7.770	NM_004688	NMI	N-myc (and STAT) interactor
chrX_+_131157231	7.603	NM_001042453 NM_016542	MST4	serine/threonine protein kinase MST4
chr19_+_49838673	7.587	NM_001040031 NM_001774	CD37	CD37 molecule
chr5_-_88119604	7.552	NM_001193348 NM_001193349	MEF2C	myocyte enhancer factor 2C
chr17_-_4851827	7.510		PFN1	profilin 1
chr1_-_154578775	7.473	NM_001193495	ADAR	adenosine deaminase, RNA-specific
chrX_+_70765479	7.433		OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
chr1_-_154600383	7.343		ADAR	adenosine deaminase, RNA-specific
chr7_+_26403944	7.340	NM_001199838	SNX10	sorting nexin 10
chr1_-_27226928	7.335		GPATCH3	G patch domain containing 3
chr19_+_36705979	7.299		ZNF146	zinc finger protein 146
chr7_-_37488408	7.277		ELMO1	engulfment and cell motility 1
chr1_-_159895279	7.265	NM_003564	TAGLN2	transgelin 2
chr7_+_5013618	7.264		RNF216P1	ring finger protein 216 pseudogene 1
chr15_+_66694216	7.212		MAP2K1	mitogen-activated protein kinase kinase 1
chr17_-_4851797	7.206	NM_005022	PFN1	profilin 1
chr14_-_106539099	7.173		IGHA1 IGHG1 IGHG3	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr3_-_81810914	7.143	NM_000158	GBE1	glucan (1,4-alpha-), branching enzyme 1
chr13_+_53216564	7.116		HNRNPA1L2	heterogeneous nuclear ribonucleoprotein A1-like 2
chr14_+_23235730	7.110	NM_005015	OXA1L	oxidase (cytochrome c) assembly 1-like
chr5_-_134734796	7.077		H2AFY	H2A histone family, member Y
chr6_+_32605182	7.032	NM_002122	HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1
chr14_-_24616429	7.005		PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr10_-_27057776	6.998		ABI1	abl-interactor 1
chr6_-_86352635	6.954	NM_001159673	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr21_-_46340821	6.925		ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr8_+_41348067	6.873	NM_001174124 NM_016099	GOLGA7	golgin A7
chrX_+_123234462	6.847		STAG2	stromal antigen 2
chr21_-_46340776	6.820		ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr8_+_41348126	6.743	NM_001002296	GOLGA7	golgin A7
chr1_+_26856252	6.742		RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr2_-_152146133	6.697		NMI	N-myc (and STAT) interactor
chr12_+_69742130	6.656	NM_000239	LYZ	lysozyme
chr8_+_41348094	6.638		GOLGA7	golgin A7
chr11_-_111250156	6.623	NM_006235	POU2AF1	POU class 2 associating factor 1
chr16_+_30075715	6.614	NM_001127617	ALDOA	aldolase A, fructose-bisphosphate
chr8_+_41348105	6.563		GOLGA7	golgin A7
chr16_-_46723024	6.546		VPS35	vacuolar protein sorting 35 homolog (S. cerevisiae)
chr19_+_49838700	6.499		CD37	CD37 molecule
chr19_+_49838646	6.499		CD37	CD37 molecule
chr7_+_98972351	6.486		ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa
chr1_-_159895258	6.484		TAGLN2	transgelin 2
chr10_+_11060069	6.465		CELF2	CUGBP, Elav-like family member 2
chr6_-_32634287	6.463	NM_001243961 NM_002123	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1
chr1_+_24286300	6.463	NM_017761	PNRC2	proline-rich nuclear receptor coactivator 2
chr19_-_8642309	6.449	NM_012335	MYO1F	myosin IF
chrX_+_13707236	6.422	NM_001195328 NM_004251	RAB9A	RAB9A, member RAS oncogene family
chr14_-_106877689	6.374		IGHV4-31 IGH@ IGHA1 IGHA2 IGHG1 IGHG4 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy locus immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 4 (G4m marker) immunoglobulin heavy constant mu
chr22_+_43547558	6.370		TSPO	translocator protein (18kDa)
chr2_+_68592432	6.360		PLEK	pleckstrin
chr1_+_211519705	6.324	NM_145759	TRAF5	TNF receptor-associated factor 5
chrX_-_153602998	6.306	NM_001110556 NM_001456	FLNA	filamin A, alpha
chr1_-_245025958	6.289		HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr22_+_22569155	6.273
chr1_+_32687970	6.273	NM_003757	EIF3I	eukaryotic translation initiation factor 3, subunit I
chr12_-_49318663	6.264	NM_001143781	FKBP11	FK506 binding protein 11, 19 kDa
chr12_+_25205180	6.263	NM_001204126 NM_001204127 NM_006152	LRMP	lymphoid-restricted membrane protein
chr6_-_32821743	6.258	NM_000593	TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr1_-_154600446	6.248	NM_001025107	ADAR	adenosine deaminase, RNA-specific
chr1_-_235292206	6.189	NM_014765	TOMM20	translocase of outer mitochondrial membrane 20 homolog (yeast)
chr19_+_49838734	6.176		CD37	CD37 molecule
chr16_-_28223161	6.172	NM_015171	XPO6	exportin 6
chr10_-_121296044	6.169	NM_002925	RGS10	regulator of G-protein signaling 10
chr6_-_86352982	6.143	NM_001159677 NM_006372	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr11_+_1889902	6.141	NM_001013253	LSP1	lymphocyte-specific protein 1
chr10_-_120938276	6.114		PRDX3	peroxiredoxin 3
chr12_-_46662533	6.102		SLC38A1	solute carrier family 38, member 1
chr14_+_105953531	6.087		CRIP1	cysteine-rich protein 1 (intestinal)
chr22_+_37257004	6.085	NM_000631 NM_013416	NCF4	neutrophil cytosolic factor 4, 40kDa
chr1_+_24286311	6.077		PNRC2	proline-rich nuclear receptor coactivator 2
chr8_-_101962767	6.073	NM_001135702	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr10_-_98031154	6.009	NM_001114094 NM_013314	BLNK	B-cell linker
chr6_-_32812711	6.001	NM_004159	PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr15_+_77287738	5.965		PSTPIP1	proline-serine-threonine phosphatase interacting protein 1
chr20_-_34329872	5.961		RBM39	RNA binding motif protein 39
chr7_-_87849341	5.951		SRI	sorcin
chr10_-_81965332	5.944		ANXA11	annexin A11
chr4_-_83350829	5.933		HNRPDL	heterogeneous nuclear ribonucleoprotein D-like
chr3_-_146262277	5.923		PLSCR1	phospholipid scramblase 1
chr3_+_121774208	5.920	NM_001206924 NM_001206925 NM_175862	CD86	CD86 molecule
chr3_+_50126340	5.920	NM_005778	RBM5	RNA binding motif protein 5
chr1_+_26644380	5.915	NM_001803	CD52	CD52 molecule
chr8_-_134072404	5.901	NM_006748	SLA	Src-like-adaptor
chr9_+_112542496	5.866	NM_053016 NM_007203 NM_147150	PALM2 PALM2-AKAP2	paralemmin 2 PALM2-AKAP2 readthrough
chr10_-_81965113	5.846		ANXA11	annexin A11
chr1_+_112162397	5.807	NM_001010935 NM_002884	RAP1A	RAP1A, member of RAS oncogene family
chr13_+_31309690	5.799		ALOX5AP	arachidonate 5-lipoxygenase-activating protein
chr19_-_8642297	5.765		MYO1F	myosin IF
chr9_-_137809710	5.756	NM_002003	FCN1	ficolin (collagen/fibrinogen domain containing) 1
chr15_+_44038483	5.724	NM_005313	PDIA3	protein disulfide isomerase family A, member 3
chr5_+_177631496	5.709	NM_004499 NM_031266	HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B
chrX_+_128913897	5.707		SASH3	SAM and SH3 domain containing 3
chr9_+_77703395	5.697	NM_012383	OSTF1	osteoclast stimulating factor 1
chr14_+_70233862	5.686		SRSF5	serine/arginine-rich splicing factor 5
chr1_+_110091218	5.680		GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr2_+_219081898	5.672		ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa
chrX_+_128913881	5.598	NM_018990	SASH3	SAM and SH3 domain containing 3
chr17_-_29641094	5.597	NM_006495	EVI2B	ecotropic viral integration site 2B
chr7_+_98972326	5.584		ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa
chr17_-_76128487	5.581	NM_007267	TMC6	transmembrane channel-like 6
chr3_-_107809754	5.567	NM_001777 NM_198793	CD47	CD47 molecule
chr10_+_11059854	5.563	NM_006561	CELF2	CUGBP, Elav-like family member 2
chr14_+_67656109	5.552	NM_173526	FAM71D	family with sequence similarity 71, member D
chr1_+_24018293	5.548		RPL11	ribosomal protein L11
chr1_-_32385258	5.533	NM_001195100 NM_001195101	PTP4A2	protein tyrosine phosphatase type IVA, member 2
chr1_+_53480573	5.517	NM_001007099 NM_001007100 NM_001007250	SCP2	sterol carrier protein 2
chr1_+_53480616	5.482		SCP2	sterol carrier protein 2
chr20_+_3869593	5.470	NM_153638	PANK2	pantothenate kinase 2
chr11_+_5710926	5.470		TRIM22	tripartite motif containing 22
chr1_+_153330329	5.468	NM_002965	S100A9	S100 calcium binding protein A9
chr2_-_158731622	5.460	NM_001105	ACVR1	activin A receptor, type I
chr2_-_145277879	5.444	NM_001171653 NM_014795	ZEB2	zinc finger E-box binding homeobox 2
chr1_+_32688010	5.429		EIF3I	eukaryotic translation initiation factor 3, subunit I
chr12_+_54891539	5.428		NCKAP1L	NCK-associated protein 1-like
chr12_-_110888079	5.422		ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa
chr1_+_26856240	5.401	NM_002953	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr20_+_57464156	5.400		GNAS	GNAS complex locus
chr15_+_44038649	5.386		PDIA3	protein disulfide isomerase family A, member 3

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.23	5.15e-39	GO:0009987	cellular process
1.51	2.79e-29	GO:0044260	cellular macromolecule metabolic process
1.37	1.52e-26	GO:0044237	cellular metabolic process
1.43	2.06e-25	GO:0043170	macromolecule metabolic process
1.35	2.63e-24	GO:0044238	primary metabolic process
1.31	1.36e-23	GO:0008152	metabolic process
1.56	1.43e-18	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.73	3.60e-18	GO:0016070	RNA metabolic process
1.61	4.12e-17	GO:0090304	nucleic acid metabolic process
1.67	1.96e-16	GO:0010467	gene expression
1.45	1.48e-14	GO:0034641	cellular nitrogen compound metabolic process
1.44	2.25e-14	GO:0006807	nitrogen compound metabolic process
1.52	3.58e-14	GO:0044267	cellular protein metabolic process
1.76	4.62e-13	GO:0002376	immune system process
2.19	1.70e-12	GO:0016071	mRNA metabolic process
1.61	6.25e-12	GO:0034645	cellular macromolecule biosynthetic process
1.60	1.45e-11	GO:0009059	macromolecule biosynthetic process
1.86	3.19e-11	GO:0008219	cell death
1.85	4.98e-11	GO:0016265	death
1.41	1.05e-10	GO:0019538	protein metabolic process
1.46	1.44e-10	GO:0044249	cellular biosynthetic process
1.37	2.36e-10	GO:0071840	cellular component organization or biogenesis
1.43	2.44e-10	GO:0048518	positive regulation of biological process
1.21	8.21e-10	GO:0050789	regulation of biological process
1.36	1.04e-09	GO:0016043	cellular component organization
1.89	1.45e-09	GO:0012501	programmed cell death
1.89	2.25e-09	GO:0006915	apoptosis
1.42	4.37e-09	GO:0009058	biosynthetic process
2.85	7.05e-09	GO:0002757	immune response-activating signal transduction
1.18	1.18e-08	GO:0065007	biological regulation
1.42	1.44e-08	GO:0006950	response to stress
2.78	1.86e-08	GO:0002764	immune response-regulating signaling pathway
2.09	2.54e-08	GO:0050776	regulation of immune response
1.39	2.76e-08	GO:0071841	cellular component organization or biogenesis at cellular level
1.85	3.57e-08	GO:0002682	regulation of immune system process
1.78	5.09e-08	GO:0046907	intracellular transport
1.39	5.81e-08	GO:0071842	cellular component organization at cellular level
1.79	8.11e-08	GO:0006955	immune response
1.19	1.23e-07	GO:0050794	regulation of cellular process
1.74	1.25e-07	GO:0043933	macromolecular complex subunit organization
2.09	1.67e-07	GO:0016032	viral reproduction
1.98	2.50e-07	GO:0034621	cellular macromolecular complex subunit organization
1.39	4.53e-07	GO:0048522	positive regulation of cellular process
2.47	4.96e-07	GO:0002253	activation of immune response
1.82	7.33e-07	GO:0006396	RNA processing
1.56	9.67e-07	GO:0051641	cellular localization
1.30	1.25e-06	GO:0051179	localization
1.48	1.40e-06	GO:0006996	organelle organization
2.05	1.78e-06	GO:0006397	mRNA processing
1.64	1.91e-06	GO:0032774	RNA biosynthetic process
1.58	2.63e-06	GO:0051649	establishment of localization in cell
1.61	2.95e-06	GO:0032268	regulation of cellular protein metabolic process
2.49	3.48e-06	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.49	3.48e-06	GO:0000398	nuclear mRNA splicing, via spliceosome
3.12	3.95e-06	GO:0002429	immune response-activating cell surface receptor signaling pathway
2.16	4.41e-06	GO:0006412	translation
1.59	4.97e-06	GO:0010941	regulation of cell death
1.59	5.05e-06	GO:0043067	regulation of programmed cell death
2.05	6.65e-06	GO:0044419	interspecies interaction between organisms
2.15	7.29e-06	GO:0008380	RNA splicing
2.42	9.04e-06	GO:0000375	RNA splicing, via transesterification reactions
1.25	1.15e-05	GO:0051716	cellular response to stimulus
3.00	1.20e-05	GO:0002768	immune response-regulating cell surface receptor signaling pathway
1.56	1.36e-05	GO:0051246	regulation of protein metabolic process
1.72	1.51e-05	GO:0065003	macromolecular complex assembly
1.58	1.56e-05	GO:0042981	regulation of apoptosis
1.40	1.76e-05	GO:0043412	macromolecule modification
2.15	1.80e-05	GO:0050778	positive regulation of immune response
1.78	2.15e-05	GO:0071822	protein complex subunit organization
2.83	2.26e-05	GO:0050657	nucleic acid transport
2.83	2.26e-05	GO:0050658	RNA transport
2.83	2.26e-05	GO:0051236	establishment of RNA localization
1.76	2.51e-05	GO:0009057	macromolecule catabolic process
1.40	4.52e-05	GO:0006464	protein modification process
1.48	5.31e-05	GO:0033036	macromolecule localization
2.74	5.85e-05	GO:0006403	RNA localization
1.56	6.18e-05	GO:0007049	cell cycle
1.27	6.87e-05	GO:0007165	signal transduction
1.87	7.08e-05	GO:0002684	positive regulation of immune system process
1.25	8.03e-05	GO:0019222	regulation of metabolic process
1.34	8.27e-05	GO:0048519	negative regulation of biological process
1.99	9.24e-05	GO:0018193	peptidyl-amino acid modification
1.27	1.08e-04	GO:0060255	regulation of macromolecule metabolic process
1.96	1.13e-04	GO:0034622	cellular macromolecular complex assembly
1.62	1.14e-04	GO:0006952	defense response
1.74	1.20e-04	GO:0000278	mitotic cell cycle
2.98	1.27e-04	GO:0050851	antigen receptor-mediated signaling pathway
1.60	1.76e-04	GO:0033554	cellular response to stress
1.70	1.88e-04	GO:0051726	regulation of cell cycle
2.33	1.91e-04	GO:0022411	cellular component disassembly
2.33	1.91e-04	GO:0071845	cellular component disassembly at cellular level
1.37	2.83e-04	GO:0048583	regulation of response to stimulus
2.00	3.56e-04	GO:0051325	interphase
1.48	3.58e-04	GO:0044085	cellular component biogenesis
2.74	3.69e-04	GO:0051028	mRNA transport
2.51	4.35e-04	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
2.00	4.39e-04	GO:0051329	interphase of mitotic cell cycle
1.51	4.60e-04	GO:0022607	cellular component assembly
1.43	4.65e-04	GO:0009056	catabolic process
1.56	5.49e-04	GO:0006351	transcription, DNA-dependent
1.58	8.12e-04	GO:0031399	regulation of protein modification process
1.23	9.37e-04	GO:0023052	signaling
1.72	9.48e-04	GO:0044265	cellular macromolecule catabolic process
1.98	1.12e-03	GO:0006366	transcription from RNA polymerase II promoter
2.95	1.33e-03	GO:0022618	ribonucleoprotein complex assembly
1.26	1.48e-03	GO:0051234	establishment of localization
1.27	1.68e-03	GO:0006810	transport
1.99	1.85e-03	GO:0010608	posttranscriptional regulation of gene expression
1.55	1.96e-03	GO:0022402	cell cycle process
2.25	2.18e-03	GO:0006913	nucleocytoplasmic transport
1.41	2.62e-03	GO:0035556	intracellular signal transduction
2.22	3.00e-03	GO:0051169	nuclear transport
3.82	3.35e-03	GO:0006413	translational initiation
2.08	3.40e-03	GO:0048011	nerve growth factor receptor signaling pathway
1.31	3.60e-03	GO:0048523	negative regulation of cellular process
1.90	4.23e-03	GO:0031401	positive regulation of protein modification process
2.93	4.33e-03	GO:0050852	T cell receptor signaling pathway
2.78	4.64e-03	GO:0071826	ribonucleoprotein complex subunit organization
1.58	4.74e-03	GO:0022403	cell cycle phase
1.55	4.75e-03	GO:0016192	vesicle-mediated transport
2.01	5.76e-03	GO:0032269	negative regulation of cellular protein metabolic process
1.22	6.01e-03	GO:0031323	regulation of cellular metabolic process
1.51	6.02e-03	GO:0045184	establishment of protein localization
3.04	6.34e-03	GO:0071214	cellular response to abiotic stimulus
2.52	6.44e-03	GO:0051320	S phase
3.13	6.52e-03	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
3.13	6.52e-03	GO:0072395	signal transduction involved in cell cycle checkpoint
3.13	6.52e-03	GO:0072401	signal transduction involved in DNA integrity checkpoint
3.13	6.52e-03	GO:0072404	signal transduction involved in G1/S transition checkpoint
3.13	6.52e-03	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint
3.13	6.52e-03	GO:0072422	signal transduction involved in DNA damage checkpoint
3.13	6.52e-03	GO:0072431	signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
3.13	6.52e-03	GO:0072474	signal transduction involved in mitotic cell cycle G1/S checkpoint
2.79	6.54e-03	GO:2000045	regulation of G1/S transition of mitotic cell cycle
1.51	6.69e-03	GO:0015031	protein transport
1.78	8.32e-03	GO:0032270	positive regulation of cellular protein metabolic process
3.08	8.69e-03	GO:0031294	lymphocyte costimulation
3.08	8.69e-03	GO:0031295	T cell costimulation
1.97	8.82e-03	GO:0051248	negative regulation of protein metabolic process
2.82	9.20e-03	GO:0031575	mitotic cell cycle G1/S transition checkpoint
2.82	9.20e-03	GO:0071779	G1/S transition checkpoint
1.64	9.40e-03	GO:0006928	cellular component movement
1.51	1.06e-02	GO:0044093	positive regulation of molecular function
1.92	1.06e-02	GO:0007346	regulation of mitotic cell cycle
1.75	1.09e-02	GO:0051247	positive regulation of protein metabolic process
2.95	1.09e-02	GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint
1.70	1.29e-02	GO:0016044	cellular membrane organization
2.48	1.37e-02	GO:0000084	S phase of mitotic cell cycle
2.98	1.51e-02	GO:0071158	positive regulation of cell cycle arrest
1.69	1.55e-02	GO:0061024	membrane organization
1.79	1.59e-02	GO:0012502	induction of programmed cell death
2.27	1.62e-02	GO:0000082	G1/S transition of mitotic cell cycle
2.45	1.66e-02	GO:0008624	induction of apoptosis by extracellular signals
2.59	1.78e-02	GO:0002758	innate immune response-activating signal transduction
1.41	1.80e-02	GO:0044248	cellular catabolic process
1.43	2.08e-02	GO:0008104	protein localization
2.76	2.09e-02	GO:0008063	Toll signaling pathway
2.76	2.09e-02	GO:0034142	toll-like receptor 4 signaling pathway
1.57	2.19e-02	GO:0051276	chromosome organization
1.40	2.36e-02	GO:0010604	positive regulation of macromolecule metabolic process
2.46	2.37e-02	GO:0090068	positive regulation of cell cycle process
1.51	2.64e-02	GO:0071844	cellular component assembly at cellular level
2.54	2.69e-02	GO:0002218	activation of innate immune response
2.04	2.70e-02	GO:0022613	ribonucleoprotein complex biogenesis
1.64	2.71e-02	GO:0070271	protein complex biogenesis
2.16	2.80e-02	GO:0031400	negative regulation of protein modification process
1.76	2.92e-02	GO:0006917	induction of apoptosis
1.65	3.55e-02	GO:0006325	chromatin organization
1.63	3.90e-02	GO:0006461	protein complex assembly
2.39	4.16e-02	GO:0016197	endosome transport
1.99	4.22e-02	GO:0071843	cellular component biogenesis at cellular level
1.73	4.22e-02	GO:0016568	chromatin modification
1.37	4.25e-02	GO:0009893	positive regulation of metabolic process
2.12	4.37e-02	GO:0006417	regulation of translation
2.58	4.48e-02	GO:0002224	toll-like receptor signaling pathway
2.88	4.58e-02	GO:0031124	mRNA 3'-end processing
2.88	4.58e-02	GO:0034138	toll-like receptor 3 signaling pathway
1.62	4.78e-02	GO:0001775	cell activation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.22	3.63e-39	GO:0044424	intracellular part
1.21	2.42e-36	GO:0005622	intracellular
1.30	1.28e-31	GO:0005737	cytoplasm
1.22	1.66e-24	GO:0043229	intracellular organelle
1.22	2.33e-24	GO:0043226	organelle
1.24	2.27e-23	GO:0043227	membrane-bounded organelle
1.24	2.35e-23	GO:0043231	intracellular membrane-bounded organelle
1.71	6.42e-23	GO:0005829	cytosol
1.50	8.76e-23	GO:0032991	macromolecular complex
1.31	7.90e-19	GO:0044444	cytoplasmic part
1.32	1.32e-17	GO:0044446	intracellular organelle part
1.31	6.04e-17	GO:0005634	nucleus
1.31	1.79e-16	GO:0044422	organelle part
1.46	6.57e-15	GO:0043234	protein complex
1.55	1.97e-14	GO:0044428	nuclear part
1.51	1.65e-13	GO:0031974	membrane-enclosed lumen
1.58	2.16e-13	GO:0031981	nuclear lumen
1.51	3.48e-13	GO:0070013	intracellular organelle lumen
1.70	4.69e-13	GO:0005654	nucleoplasm
1.50	7.06e-13	GO:0043233	organelle lumen
1.07	7.17e-12	GO:0044464	cell part
1.07	7.58e-12	GO:0005623	cell
1.99	3.24e-09	GO:0030529	ribonucleoprotein complex
1.76	8.69e-08	GO:0044451	nucleoplasm part
1.31	6.44e-06	GO:0043228	non-membrane-bounded organelle
1.31	6.44e-06	GO:0043232	intracellular non-membrane-bounded organelle
3.60	8.15e-05	GO:0034708	methyltransferase complex
3.60	8.15e-05	GO:0035097	histone methyltransferase complex
1.75	2.47e-04	GO:0005768	endosome
5.30	1.62e-03	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
2.01	1.68e-03	GO:0016604	nuclear body
1.90	2.06e-03	GO:0000323	lytic vacuole
1.90	2.06e-03	GO:0005764	lysosome
1.45	2.23e-03	GO:0005794	Golgi apparatus
8.18	4.36e-03	GO:0005885	Arp2/3 protein complex
1.28	5.88e-03	GO:0031090	organelle membrane
2.88	7.73e-03	GO:0000502	proteasome complex
1.57	8.72e-03	GO:0005694	chromosome
4.52	2.71e-02	GO:0031201	SNARE complex
1.74	2.86e-02	GO:0015629	actin cytoskeleton
1.71	2.95e-02	GO:0005773	vacuole
2.07	3.43e-02	GO:0005769	early endosome

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.42	1.35e-49	GO:0005515	protein binding
1.17	7.38e-28	GO:0005488	binding
1.83	1.01e-10	GO:0003723	RNA binding
1.32	1.06e-04	GO:0000166	nucleotide binding
1.22	5.42e-03	GO:0003676	nucleic acid binding
3.49	6.73e-03	GO:0043021	ribonucleoprotein binding
3.34	2.39e-02	GO:0003823	antigen binding