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• Activity deltas table
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Motif ID: NR4A2.p2

Z-value: 1.837

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr20_-_62130390	24.008	NM_001958	EEF1A2	eukaryotic translation elongation factor 1 alpha 2
chr12_-_16759531	22.737	NM_018640	LMO3	LIM domain only 3 (rhombotin-like 2)
chr12_-_16759430	20.469		LMO3	LIM domain only 3 (rhombotin-like 2)
chr12_-_16759939	19.086	NM_001243613	LMO3	LIM domain only 3 (rhombotin-like 2)
chr1_+_236849753	18.130	NM_001103	ACTN2	actinin, alpha 2
chr12_-_16759733	14.696	NM_001243610	LMO3	LIM domain only 3 (rhombotin-like 2)
chr5_+_80529138	14.666	NM_001099735 NM_001099736 NM_001825	CKMT2	creatine kinase, mitochondrial 2 (sarcomeric)
chr12_-_16760935	13.682	NM_001001395 NM_001243609	LMO3	LIM domain only 3 (rhombotin-like 2)
chr12_-_16758839	13.641	NM_001243612	LMO3	LIM domain only 3 (rhombotin-like 2)
chr8_+_145149985	13.211		CYC1	cytochrome c-1
chr1_-_229569839	13.125	NM_001100	ACTA1	actin, alpha 1, skeletal muscle
chr11_-_64528186	12.903	NM_001164716 NM_005609	PYGM	phosphorylase, glycogen, muscle
chr22_-_36019363	12.569	NM_203377	MB	myoglobin
chr1_-_154164551	12.391	NM_152263	TPM3	tropomyosin 3
chr17_+_4854383	12.274	NM_001193503 NM_001976 NM_053013	ENO3	enolase 3 (beta, muscle)
chr3_-_47957475	11.905
chr15_+_43885251	10.971	NM_020990	CKMT1B CKMT1A	creatine kinase, mitochondrial 1B creatine kinase, mitochondrial 1A
chr1_+_55464605	9.970	NM_057176	BSND	Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr19_+_35629727	9.412	NM_021902	FXYD1	FXYD domain containing ion transport regulator 1
chrX_+_38420690	8.712	NM_004615	TSPAN7	tetraspanin 7
chr16_+_58534045	8.462	NM_001242833 NM_001242834 NM_001242835 NM_001242836	NDRG4	NDRG family member 4
chr14_-_103988829	8.237		CKB	creatine kinase, brain
chr17_+_79670396	8.141	NM_002949	MRPL12	mitochondrial ribosomal protein L12
chr2_-_176046120	8.098	NM_001002258 NM_001190329 NM_001689	ATP5G3	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr7_-_10979683	7.950		NDUFA4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr1_+_160085519	7.925	NM_000702	ATP1A2	ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr3_-_46718898	7.660	NM_182775	ALS2CL	ALS2 C-terminal like
chr3_-_50340979	7.635	NM_007312 NM_033159 NM_153282 NM_153283 NM_153285	HYAL1	hyaluronoglucosaminidase 1
chr17_+_79670495	7.512		MRPL12	mitochondrial ribosomal protein L12
chr1_+_171810611	7.492	NM_001136127 NM_015569	DNM3	dynamin 3
chr9_+_130965666	7.471		DNM1	dynamin 1
chr1_+_36023389	7.434	NM_001014839 NM_001014841 NM_014284	NCDN	neurochondrin
chr16_+_72097124	7.287	NM_020995	HPR	haptoglobin-related protein
chr10_+_88428167	6.949	NM_001171610	LDB3	LIM domain binding 3
chr2_+_234621637	6.926	NM_019078	UGT1A5	UDP glucuronosyltransferase 1 family, polypeptide A5
chr12_+_6421816	6.870	NM_001144857	PLEKHG6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr16_+_6069094	6.826	NM_001142333 NM_018723	RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr22_-_39240016	6.757	NM_014293	NPTXR	neuronal pentraxin receptor
chr2_-_211168315	6.727	NM_079422	MYL1	myosin, light chain 1, alkali; skeletal, fast
chr9_+_130965608	6.710	NM_001005336 NM_004408	DNM1	dynamin 1
chr11_+_116700620	6.707	NM_000040	APOC3	apolipoprotein C-III
chr17_-_26903926	6.689	NM_005165	ALDOC	aldolase C, fructose-bisphosphate
chr15_-_75230354	6.614		COX5A	cytochrome c oxidase subunit Va
chr20_+_17207680	6.559		PCSK2	proprotein convertase subtilisin/kexin type 2
chr9_+_130965668	6.475		DNM1	dynamin 1
chr3_-_194072004	6.474	NM_001080513	CPN2	carboxypeptidase N, polypeptide 2
chr1_+_64088886	6.282	NM_001172818	PGM1	phosphoglucomutase 1
chr17_-_42992852	6.275	NM_001131019 NM_001242376 NM_002055	GFAP	glial fibrillary acidic protein
chr11_+_65190272	6.245
chr14_+_100150596	6.166	NM_006668	CYP46A1	cytochrome P450, family 46, subfamily A, polypeptide 1
chr8_+_145149978	6.155		CYC1	cytochrome c-1
chr2_+_74273449	6.038	NM_144993	TET3	tet methylcytosine dioxygenase 3
chr8_+_145149936	5.945	NM_001916	CYC1	cytochrome c-1
chr12_-_120554558	5.938		RAB35	RAB35, member RAS oncogene family
chr3_-_48647052	5.937		UQCRC1	ubiquinol-cytochrome c reductase core protein I
chr3_-_48647085	5.919	NM_003365	UQCRC1	ubiquinol-cytochrome c reductase core protein I
chr22_-_44258210	5.895	NM_014351	SULT4A1	sulfotransferase family 4A, member 1
chr17_-_26903854	5.829		ALDOC	aldolase C, fructose-bisphosphate
chr7_+_149571029	5.823		ATP6V0E2	ATPase, H+ transporting V0 subunit e2
chr7_-_44180911	5.821	NM_021223	MYL7	myosin, light chain 7, regulatory
chr3_+_195384918	5.763		SDHAP1 SDHAP2	succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2
chr1_+_233749749	5.649	NM_002245	KCNK1	potassium channel, subfamily K, member 1
chr4_+_41614911	5.646	NM_001112719 NM_001112720	LIMCH1	LIM and calponin homology domains 1
chrX_-_21776158	5.533	NM_014332	SMPX	small muscle protein, X-linked
chr2_+_234637772	5.476	NM_019093	UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3
chr19_+_35630391	5.290	NM_005031	FXYD1	FXYD domain containing ion transport regulator 1
chr12_-_45307710	5.269	NM_001145110	NELL2	NEL-like 2 (chicken)
chr9_+_17578952	5.265	NM_003026	SH3GL2	SH3-domain GRB2-like 2
chr5_-_134914968	5.201	NM_004887	CXCL14	chemokine (C-X-C motif) ligand 14
chr16_+_30386097	5.186	NM_013292	MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle
chr1_-_161193190	5.131		APOA2	apolipoprotein A-II
chr2_+_170366211	5.128	NM_006063	KBTBD10	kelch repeat and BTB (POZ) domain containing 10
chr7_-_72936592	5.079	NM_032408	BAZ1B	bromodomain adjacent to zinc finger domain, 1B
chr17_-_8066254	5.075	NM_014232	VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)
chr2_+_98262497	5.050	NM_001862	COX5B	cytochrome c oxidase subunit Vb
chr2_+_234627423	4.963	NM_007120	UGT1A4	UDP glucuronosyltransferase 1 family, polypeptide A4
chr1_-_116311161	4.902		CASQ2	calsequestrin 2 (cardiac muscle)
chr17_-_56618178	4.882	NM_001198713	SEPT4	septin 4
chr20_+_57875647	4.873		EDN3	endothelin 3
chr3_-_52488030	4.871	NM_003280	TNNC1	troponin C type 1 (slow)
chr17_-_29624249	4.864	NM_002544	OMG	oligodendrocyte myelin glycoprotein
chr16_+_72088507	4.855	NM_001126102 NM_005143	HP	haptoglobin
chr2_-_31637553	4.824		XDH	xanthine dehydrogenase
chr12_-_52886971	4.810	NM_005554	KRT6A	keratin 6A
chr15_-_75230386	4.806	NM_004255	COX5A	cytochrome c oxidase subunit Va
chr12_+_119616594	4.789	NM_014365	HSPB8	heat shock 22kDa protein 8
chr1_-_116311330	4.754		CASQ2	calsequestrin 2 (cardiac muscle)
chr6_+_31554475	4.731	NM_205837	LST1	leukocyte specific transcript 1
chr11_-_790103	4.611	NM_016564	CEND1	cell cycle exit and neuronal differentiation 1
chr9_+_139839697	4.609	NM_000606	C8G	complement component 8, gamma polypeptide
chr1_+_64059479	4.600	NM_001172819	PGM1	phosphoglucomutase 1
chr8_-_110661007	4.571	NM_001099747 NM_001099748 NM_001099749 NM_001099750 NM_017786	SYBU	syntabulin (syntaxin-interacting)
chr8_+_21911062	4.553	NM_001114137	EPB49	erythrocyte membrane protein band 4.9 (dematin)
chr14_-_103989112	4.514		CKB	creatine kinase, brain
chr1_-_182573393	4.486	NM_002928	RGS16	regulator of G-protein signaling 16
chr19_+_54606141	4.484	NM_004542	NDUFA3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr15_+_91769329	4.471		SV2B	synaptic vesicle glycoprotein 2B
chr17_-_56606710	4.462	NM_004574	SEPT4	septin 4
chr20_-_33999760	4.447		UQCC	ubiquinol-cytochrome c reductase complex chaperone
chr2_+_210288668	4.402	NM_001039538	MAP2	microtubule-associated protein 2
chr5_-_42811959	4.336	NM_001085486 NM_001093726 NM_005410	SEPP1	selenoprotein P, plasma, 1
chr6_+_30594607	4.291	NM_024909 NM_001031722 NM_001190724	ATAT1	alpha tubulin acetyltransferase 1
chr9_-_138853146	4.231	NM_016172	UBAC1	UBA domain containing 1
chr2_-_110874142	4.181	NM_005434	MALL	mal, T-cell differentiation protein-like
chr7_-_143059144	4.164	NM_014690	FAM131B	family with sequence similarity 131, member B
chr10_+_123872440	4.135		TACC2	transforming, acidic coiled-coil containing protein 2
chr12_-_57039785	4.124	NM_001686	ATP5B	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr14_-_103989195	4.118	NM_001823	CKB	creatine kinase, brain
chr12_-_52867521	4.104	NM_173086	KRT6C	keratin 6C
chr19_-_55668956	4.081	NM_000363	TNNI3	troponin I type 3 (cardiac)
chr1_+_47603083	4.081	NM_001010969	CYP4A22	cytochrome P450, family 4, subfamily A, polypeptide 22
chr17_-_18218203	4.071	NM_004618	TOP3A	topoisomerase (DNA) III alpha
chr11_-_6462129	4.067	NM_000613	HPX	hemopexin
chr16_-_68269948	4.058	NM_024939	ESRP2	epithelial splicing regulatory protein 2
chr19_-_58067724	4.056	NM_001039654	ZNF550	zinc finger protein 550
chr20_-_48532036	4.040		SPATA2	spermatogenesis associated 2
chr2_-_152955810	4.038		CACNB4	calcium channel, voltage-dependent, beta 4 subunit
chr3_+_129247481	4.029	NM_000539	RHO	rhodopsin
chr12_+_98987674	4.021		SLC25A3	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr15_+_59908908	4.018		GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type
chr1_+_54359859	3.993	NM_000792 NM_001039715 NM_001039716 NM_213593	DIO1	deiodinase, iodothyronine, type I
chr3_+_159557649	3.978	NM_001197109	SCHIP1	schwannomin interacting protein 1
chr2_-_110873638	3.943		MALL	mal, T-cell differentiation protein-like
chr17_-_2614926	3.926	NM_015229	KIAA0664	KIAA0664
chr11_-_66139064	3.906	NM_001532	SLC29A2	solute carrier family 29 (nucleoside transporters), member 2
chr3_+_52813936	3.900	NM_001166435 NM_001166436	ITIH1	inter-alpha-trypsin inhibitor heavy chain 1
chr10_+_105036783	3.895	NM_032727	INA	internexin neuronal intermediate filament protein, alpha
chr18_-_74729049	3.892	NM_001025081 NM_001025090 NM_001025092 NM_002385	MBP	myelin basic protein
chr6_-_46293628	3.877	NM_005822	RCAN2	regulator of calcineurin 2
chr19_+_6739697	3.850	NM_004240	TRIP10	thyroid hormone receptor interactor 10
chr16_+_8807426	3.839		ABAT	4-aminobutyrate aminotransferase
chr10_-_50970321	3.833	NM_001143996 NM_001143997 NM_018245	OGDHL	oxoglutarate dehydrogenase-like
chr22_+_32149936	3.830	NM_001242897	DEPDC5	DEP domain containing 5
chr16_+_69796237	3.825	NM_007014 NM_199423	WWP2	WW domain containing E3 ubiquitin protein ligase 2
chr19_-_51869632	3.821	NM_001985	ETFB	electron-transfer-flavoprotein, beta polypeptide
chr9_-_138853007	3.819		UBAC1	UBA domain containing 1
chr11_-_107582733	3.788	NM_003063	SLN	sarcolipin
chr5_+_161274196	3.788	NM_000806	GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr1_-_230849863	3.783		AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr16_+_28891234	3.782		ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr1_+_233749917	3.777		KCNK1	potassium channel, subfamily K, member 1
chr1_+_46640748	3.743	NM_005727	TSPAN1	tetraspanin 1
chr3_+_133464883	3.735	NM_001063	TF	transferrin
chr20_-_48531986	3.730		SPATA2	spermatogenesis associated 2
chr10_-_123353771	3.719	NM_001144916	FGFR2	fibroblast growth factor receptor 2
chr3_+_132379130	3.710	NM_024818	UBA5	ubiquitin-like modifier activating enzyme 5
chr19_-_51472003	3.699	NM_001012964 NM_001012965	KLK6	kallikrein-related peptidase 6
chr22_-_29711650	3.695	NM_001007279 NM_006477	RASL10A	RAS-like, family 10, member A
chr1_-_157108169	3.693	NM_005240 NM_001145312	ETV3	ets variant 3
chr18_-_43678251	3.669		ATP5A1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr19_-_15235748	3.665		ILVBL	ilvB (bacterial acetolactate synthase)-like
chr11_+_47270433	3.657	NM_001130102	NR1H3	nuclear receptor subfamily 1, group H, member 3
chr10_-_101841593	3.646	NM_001308	CPN1	carboxypeptidase N, polypeptide 1
chr11_+_67798077	3.640	NM_002496	NDUFS8	NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr2_-_152590983	3.636	NM_001164507 NM_001164508 NM_004543	NEB	nebulin
chr2_-_21225640	3.634		APOB	apolipoprotein B (including Ag(x) antigen)
chr12_-_81991959	3.627	NM_001220477 NM_001220478	PPFIA2	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr11_-_624901	3.620	NM_001171968 NM_021924 NM_031264	CDHR5	cadherin-related family member 5
chr12_-_122296619	3.616	NM_002150	HPD	4-hydroxyphenylpyruvate dioxygenase
chr2_-_110873353	3.600		MALL	mal, T-cell differentiation protein-like
chr22_-_29711474	3.595		RASL10A	RAS-like, family 10, member A
chr5_-_176831385	3.565		F12	coagulation factor XII (Hageman factor)
chr1_+_161172125	3.548		NDUFS2	NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
chr15_+_78441737	3.540		IDH3A	isocitrate dehydrogenase 3 (NAD+) alpha
chr7_+_45614081	3.536	NM_021116	ADCY1	adenylate cyclase 1 (brain)
chr7_-_10979752	3.523	NM_002489	NDUFA4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr18_-_43678195	3.502		ATP5A1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr11_+_1860718	3.500	NM_001145829	TNNI2	troponin I type 2 (skeletal, fast)
chr18_-_43678230	3.484		ATP5A1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr10_+_105037441	3.470		INA	internexin neuronal intermediate filament protein, alpha
chr12_-_57039736	3.467		ATP5B	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr8_+_21916858	3.447		EPB49	erythrocyte membrane protein band 4.9 (dematin)
chr16_+_103827	3.423	NM_024571	SNRNP25	small nuclear ribonucleoprotein 25kDa (U11/U12)
chr12_-_56106061	3.420	NM_001144997	ITGA7	integrin, alpha 7
chr5_-_149792370	3.411	NM_001025158 NM_001025159 NM_004355	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr18_-_43678233	3.401		ATP5A1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr3_-_52312257	3.379		WDR82	WD repeat domain 82
chr16_+_103859	3.379		SNRNP25	small nuclear ribonucleoprotein 25kDa (U11/U12)
chr14_+_93389491	3.379		CHGA	chromogranin A (parathyroid secretory protein 1)
chr11_-_63933204	3.343		MACROD1	MACRO domain containing 1
chr1_+_20964414	3.342
chr16_-_89768094	3.324	NM_152339	SPATA2L	spermatogenesis associated 2-like
chr4_-_40517913	3.323	NM_019027	RBM47	RNA binding motif protein 47
chr7_+_86273219	3.313	NM_000840	GRM3	glutamate receptor, metabotropic 3
chr10_-_75634219	3.303	NM_001204492 NM_001222 NM_172169 NM_172170 NM_172171 NM_172173	CAMK2G	calcium/calmodulin-dependent protein kinase II gamma
chr19_-_51568323	3.303	NM_015596	KLK13	kallikrein-related peptidase 13
chr1_+_44412582	3.299		IPO13	importin 13
chr19_-_36246411	3.274		HSPB6	heat shock protein, alpha-crystallin-related, B6
chr1_-_201346804	3.267	NM_000364 NM_001001430 NM_001001431 NM_001001432	TNNT2	troponin T type 2 (cardiac)
chr11_-_111782447	3.265	NM_001885	CRYAB	crystallin, alpha B
chr17_-_7166263	3.247	NM_001185023 NM_001307	CLDN7	claudin 7
chr3_+_39509069	3.246	NM_182935	MOBP	myelin-associated oligodendrocyte basic protein
chr11_+_17757494	3.239	NM_001112741 NM_004976	KCNC1	potassium voltage-gated channel, Shaw-related subfamily, member 1
chr11_+_117947726	3.225	NM_001083947 NM_001173551 NM_001173552 NM_019894	TMPRSS4	transmembrane protease, serine 4
chr19_-_15235967	3.215		ILVBL	ilvB (bacterial acetolactate synthase)-like
chr4_+_76439653	3.213	NM_144721	THAP6	THAP domain containing 6
chrX_+_135230736	3.205	NM_001159700	FHL1	four and a half LIM domains 1
chr4_+_159593233	3.204	NM_004453	ETFDH	electron-transferring-flavoprotein dehydrogenase
chr1_-_27701302	3.195	NM_003665 NM_173452	FCN3	ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)
chr18_-_43678257	3.175		ATP5A1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.66	1.83e-21	GO:0006091	generation of precursor metabolites and energy
1.16	4.50e-21	GO:0009987	cellular process
2.93	2.75e-19	GO:0015980	energy derivation by oxidation of organic compounds
3.94	4.31e-19	GO:0045333	cellular respiration
4.16	5.11e-16	GO:0022904	respiratory electron transport chain
1.20	5.19e-14	GO:0065007	biological regulation
1.84	8.26e-14	GO:0055114	oxidation-reduction process
1.47	2.18e-11	GO:0065008	regulation of biological quality
3.18	3.96e-11	GO:0022900	electron transport chain
1.32	1.96e-10	GO:0023052	signaling
1.49	4.57e-10	GO:0044281	small molecule metabolic process
1.36	9.86e-10	GO:0006810	transport
1.78	1.72e-09	GO:0007267	cell-cell signaling
1.35	1.95e-09	GO:0051234	establishment of localization
1.18	3.02e-09	GO:0050789	regulation of biological process
1.66	3.45e-09	GO:0007154	cell communication
1.79	5.59e-09	GO:0042180	cellular ketone metabolic process
1.23	1.28e-08	GO:0032501	multicellular organismal process
1.29	7.23e-08	GO:0051179	localization
1.74	1.72e-07	GO:0019752	carboxylic acid metabolic process
1.74	1.72e-07	GO:0043436	oxoacid metabolic process
1.73	2.33e-07	GO:0006082	organic acid metabolic process
1.30	3.63e-07	GO:0048856	anatomical structure development
4.26	5.51e-07	GO:0042773	ATP synthesis coupled electron transport
4.26	5.51e-07	GO:0042775	mitochondrial ATP synthesis coupled electron transport
1.36	7.04e-07	GO:0042221	response to chemical stimulus
1.26	7.09e-07	GO:0032502	developmental process
1.16	1.97e-06	GO:0050794	regulation of cellular process
1.82	4.70e-06	GO:0019226	transmission of nerve impulse
1.82	4.70e-06	GO:0035637	multicellular organismal signaling
3.82	8.63e-06	GO:0006119	oxidative phosphorylation
1.17	9.31e-06	GO:0050896	response to stimulus
2.19	9.94e-06	GO:0008202	steroid metabolic process
2.37	1.01e-05	GO:0003012	muscle system process
1.57	1.33e-05	GO:0006811	ion transport
1.29	1.38e-05	GO:0048731	system development
1.26	1.56e-05	GO:0007165	signal transduction
1.25	3.34e-05	GO:0007275	multicellular organismal development
1.82	3.96e-05	GO:0007268	synaptic transmission
2.37	4.10e-05	GO:0006936	muscle contraction
1.68	4.19e-05	GO:0048878	chemical homeostasis
1.22	6.66e-05	GO:0051716	cellular response to stimulus
1.71	8.88e-05	GO:0044282	small molecule catabolic process
1.94	9.73e-05	GO:0032787	monocarboxylic acid metabolic process
1.14	1.20e-04	GO:0008152	metabolic process
4.07	1.38e-04	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
1.65	1.57e-04	GO:0009725	response to hormone stimulus
1.35	2.27e-04	GO:0007166	cell surface receptor linked signaling pathway
1.42	3.82e-04	GO:0051239	regulation of multicellular organismal process
1.66	3.95e-04	GO:0007186	G-protein coupled receptor protein signaling pathway
1.38	4.13e-04	GO:0009653	anatomical structure morphogenesis
1.41	5.20e-04	GO:0010033	response to organic substance
2.44	6.86e-04	GO:0030802	regulation of cyclic nucleotide biosynthetic process
2.44	6.86e-04	GO:0030808	regulation of nucleotide biosynthetic process
1.58	6.99e-04	GO:0009719	response to endogenous stimulus
2.49	8.60e-04	GO:0030817	regulation of cAMP biosynthetic process
2.47	1.09e-03	GO:0030814	regulation of cAMP metabolic process
1.71	1.12e-03	GO:0055082	cellular chemical homeostasis
1.51	1.31e-03	GO:0055085	transmembrane transport
2.38	1.35e-03	GO:0030799	regulation of cyclic nucleotide metabolic process
2.31	1.58e-03	GO:0006820	anion transport
1.66	1.77e-03	GO:0044283	small molecule biosynthetic process
1.67	2.26e-03	GO:0050801	ion homeostasis
1.48	2.65e-03	GO:0042592	homeostatic process
1.62	2.97e-03	GO:0019725	cellular homeostasis
1.69	3.62e-03	GO:0006873	cellular ion homeostasis
1.58	3.91e-03	GO:0009887	organ morphogenesis
3.22	5.54e-03	GO:0061041	regulation of wound healing
1.24	5.84e-03	GO:0048518	positive regulation of biological process
1.28	5.94e-03	GO:0048869	cellular developmental process
1.29	5.95e-03	GO:0030154	cell differentiation
1.34	7.68e-03	GO:0007399	nervous system development
2.80	8.58e-03	GO:0015711	organic anion transport
2.46	8.85e-03	GO:0045761	regulation of adenylate cyclase activity
2.41	1.40e-02	GO:0031279	regulation of cyclase activity
1.42	1.54e-02	GO:0006629	lipid metabolic process
1.59	1.65e-02	GO:0006753	nucleoside phosphate metabolic process
1.59	1.65e-02	GO:0009117	nucleotide metabolic process
1.13	1.67e-02	GO:0044237	cellular metabolic process
2.16	1.83e-02	GO:0006006	glucose metabolic process
2.91	1.94e-02	GO:0007194	negative regulation of adenylate cyclase activity
2.91	1.94e-02	GO:0031280	negative regulation of cyclase activity
2.91	1.94e-02	GO:0051350	negative regulation of lyase activity
1.76	1.97e-02	GO:0032870	cellular response to hormone stimulus
1.50	2.03e-02	GO:0046483	heterocycle metabolic process
2.36	2.18e-02	GO:0051339	regulation of lyase activity
1.24	2.56e-02	GO:0048522	positive regulation of cellular process
2.30	2.61e-02	GO:0003001	generation of a signal involved in cell-cell signaling
2.30	2.61e-02	GO:0023061	signal release
2.86	2.64e-02	GO:0034339	regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
1.87	2.81e-02	GO:0032101	regulation of response to external stimulus
2.08	3.40e-02	GO:0019935	cyclic-nucleotide-mediated signaling
1.62	3.57e-02	GO:0043086	negative regulation of catalytic activity
1.99	3.75e-02	GO:0006732	coenzyme metabolic process
1.53	3.86e-02	GO:0006812	cation transport
2.26	3.92e-02	GO:0019933	cAMP-mediated signaling
1.95	4.10e-02	GO:0034220	ion transmembrane transport
3.91	4.59e-02	GO:0008207	C21-steroid hormone metabolic process
1.85	4.72e-02	GO:0051186	cofactor metabolic process
4.52	4.74e-02	GO:0015985	energy coupled proton transport, down electrochemical gradient
4.52	4.74e-02	GO:0015986	ATP synthesis coupled proton transport

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
2.65	9.56e-18	GO:0005743	mitochondrial inner membrane
2.46	2.40e-15	GO:0019866	organelle inner membrane
1.50	3.07e-15	GO:0044459	plasma membrane part
1.64	9.85e-14	GO:0005739	mitochondrion
1.23	1.03e-12	GO:0044444	cytoplasmic part
2.11	5.14e-12	GO:0031966	mitochondrial membrane
1.17	5.37e-12	GO:0005737	cytoplasm
1.87	8.52e-12	GO:0044429	mitochondrial part
2.05	1.97e-11	GO:0005740	mitochondrial envelope
3.12	1.44e-10	GO:0044455	mitochondrial membrane part
1.61	4.36e-10	GO:0000267	cell fraction
1.57	6.24e-10	GO:0005887	integral to plasma membrane
1.55	1.37e-09	GO:0031226	intrinsic to plasma membrane
1.68	3.54e-09	GO:0005626	insoluble fraction
3.70	1.26e-08	GO:0070469	respiratory chain
1.25	1.26e-08	GO:0071944	cell periphery
1.25	1.55e-08	GO:0005886	plasma membrane
1.66	2.62e-08	GO:0005624	membrane fraction
1.65	8.63e-08	GO:0005615	extracellular space
1.64	9.50e-07	GO:0031975	envelope
3.47	1.47e-06	GO:0005746	mitochondrial respiratory chain
1.62	3.57e-06	GO:0031967	organelle envelope
3.97	1.40e-05	GO:0005747	mitochondrial respiratory chain complex I
3.97	1.40e-05	GO:0030964	NADH dehydrogenase complex
3.97	1.40e-05	GO:0045271	respiratory chain complex I
1.46	4.25e-05	GO:0044421	extracellular region part
1.12	1.27e-04	GO:0016020	membrane
1.04	1.75e-04	GO:0044464	cell part
1.04	1.83e-04	GO:0005623	cell
1.72	2.70e-04	GO:0043005	neuron projection
1.46	4.57e-04	GO:0042995	cell projection
1.27	8.10e-04	GO:0031090	organelle membrane
1.07	8.30e-04	GO:0044424	intracellular part
1.95	1.60e-03	GO:0030141	stored secretory granule
2.25	1.66e-03	GO:0043292	contractile fiber
1.82	2.49e-03	GO:0005759	mitochondrial matrix
1.64	3.29e-03	GO:0045202	synapse
1.06	5.36e-03	GO:0005622	intracellular
1.78	8.68e-03	GO:0042598	vesicular fraction
2.18	9.26e-03	GO:0030016	myofibril
2.82	1.31e-02	GO:0031983	vesicle lumen
1.78	1.42e-02	GO:0005792	microsome
2.16	1.44e-02	GO:0044449	contractile fiber part
1.12	1.98e-02	GO:0044422	organelle part
4.31	3.06e-02	GO:0005753	mitochondrial proton-transporting ATP synthase complex
1.85	3.82e-02	GO:0030424	axon
6.11	3.90e-02	GO:0034366	spherical high-density lipoprotein particle
5.18	4.47e-02	GO:0001917	photoreceptor inner segment
1.64	4.58e-02	GO:0044456	synapse part
1.38	4.74e-02	GO:0031982	vesicle
1.12	4.96e-02	GO:0044446	intracellular organelle part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.16	2.19e-07	GO:0005515	protein binding
1.67	5.81e-07	GO:0016491	oxidoreductase activity
1.08	7.40e-07	GO:0005488	binding
1.64	1.00e-06	GO:0015075	ion transmembrane transporter activity
1.48	2.19e-06	GO:0005215	transporter activity
1.53	6.52e-06	GO:0022857	transmembrane transporter activity
4.18	8.57e-06	GO:0003954	NADH dehydrogenase activity
4.18	8.57e-06	GO:0008137	NADH dehydrogenase (ubiquinone) activity
4.18	8.57e-06	GO:0050136	NADH dehydrogenase (quinone) activity
1.50	8.68e-06	GO:0022892	substrate-specific transporter activity
2.24	2.10e-05	GO:0015077	monovalent inorganic cation transmembrane transporter activity
1.52	3.68e-05	GO:0022891	substrate-specific transmembrane transporter activity
1.47	7.69e-05	GO:0005102	receptor binding
2.98	1.16e-04	GO:0005200	structural constituent of cytoskeleton
3.60	1.86e-04	GO:0016655	oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
3.35	1.87e-04	GO:0003707	steroid hormone receptor activity
1.99	1.87e-04	GO:0022890	inorganic cation transmembrane transporter activity
2.60	2.67e-04	GO:0015078	hydrogen ion transmembrane transporter activity
1.61	3.28e-04	GO:0008324	cation transmembrane transporter activity
3.17	5.88e-04	GO:0004879	ligand-dependent nuclear receptor activity
2.22	6.83e-04	GO:0008509	anion transmembrane transporter activity
2.61	2.17e-03	GO:0016651	oxidoreductase activity, acting on NADH or NADPH
1.64	2.53e-03	GO:0008289	lipid binding
2.91	5.11e-03	GO:0033293	monocarboxylic acid binding
1.14	5.15e-03	GO:0003824	catalytic activity
2.63	1.79e-02	GO:0005496	steroid binding
1.63	2.80e-02	GO:0022804	active transmembrane transporter activity
3.62	3.19e-02	GO:0051539	4 iron, 4 sulfur cluster binding
1.97	4.19e-02	GO:0031406	carboxylic acid binding
1.98	4.66e-02	GO:0004252	serine-type endopeptidase activity