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• Activity deltas table
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Motif ID: NRF1.p2

Z-value: 7.939

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr9_+_110045516	148.800	NM_002874	RAD23B	RAD23 homolog B (S. cerevisiae)
chr9_+_110045551	141.032		RAD23B	RAD23 homolog B (S. cerevisiae)
chr12_+_131356557	131.599	NM_006325	RAN	RAN, member RAS oncogene family
chr2_+_264843	122.474	NM_001040649 NM_004300 NM_007099	ACP1	acid phosphatase 1, soluble
chr5_+_170814707	122.259	NM_001037738 NM_002520 NM_199185	NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr12_+_131356617	118.029		RAN	RAN, member RAS oncogene family
chr9_+_110045565	116.429		RAD23B	RAD23 homolog B (S. cerevisiae)
chr19_-_50432952	112.614	NM_016553	NUP62	nucleoporin 62kDa
chr5_+_170814952	111.630		NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr2_-_33824294	111.598	NM_015475	FAM98A	family with sequence similarity 98, member A
chr11_-_64545231	102.151	NM_001178031	SF1	splicing factor 1
chr8_-_117887045	101.282	NM_006265	RAD21	RAD21 homolog (S. pombe)
chr8_-_117886881	100.019		RAD21	RAD21 homolog (S. pombe)
chr19_-_50432734	96.429	NM_012346 NM_153718 NM_153719 NM_001193357 NM_172374	NUP62 IL4I1	nucleoporin 62kDa interleukin 4 induced 1
chr17_+_49337909	94.581		UTP18	UTP18 small subunit (SSU) processome component homolog (yeast)
chr12_-_54070108	92.998	NM_005176	ATP5G2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr17_+_49337892	92.058	NM_016001	UTP18	UTP18 small subunit (SSU) processome component homolog (yeast)
chr8_+_42249383	91.510		VDAC3	voltage-dependent anion channel 3
chr16_-_66864864	89.963	NM_001018159 NM_001018160 NM_003905	NAE1	NEDD8 activating enzyme E1 subunit 1
chr16_-_66864803	89.413		NAE1	NEDD8 activating enzyme E1 subunit 1
chr17_+_49337882	85.202		UTP18	UTP18 small subunit (SSU) processome component homolog (yeast)
chr1_-_156308099	83.169	NM_001008800 NM_005998	CCT3	chaperonin containing TCP1, subunit 3 (gamma)
chr8_+_42249278	82.983	NM_001135694 NM_005662	VDAC3	voltage-dependent anion channel 3
chr5_-_133561805	79.187	NM_002715	PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme
chr19_-_55918980	78.940		UBE2S	ubiquitin-conjugating enzyme E2S
chr20_-_57617836	78.710	NM_016045	SLMO2	slowmo homolog 2 (Drosophila)
chr1_-_156308064	78.312		CCT3	chaperonin containing TCP1, subunit 3 (gamma)
chrX_-_16888462	76.339	NM_002893	RBBP7	retinoblastoma binding protein 7
chr1_-_156308047	75.760		CCT3	chaperonin containing TCP1, subunit 3 (gamma)
chr9_-_124922049	75.021	NM_014222	NDUFA8	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
chrX_-_153707595	74.820	NM_006014	LAGE3	L antigen family, member 3
chr19_-_2427530	74.607		TIMM13	translocase of inner mitochondrial membrane 13 homolog (yeast)
chr12_-_54069856	73.721		ATP5G2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr8_+_42249393	73.599		VDAC3	voltage-dependent anion channel 3
chr1_-_156307971	73.282		CCT3	chaperonin containing TCP1, subunit 3 (gamma)
chr14_-_23058062	73.213		DAD1	defender against cell death 1
chr4_-_120987890	72.571	NM_002358	MAD2L1	MAD2 mitotic arrest deficient-like 1 (yeast)
chr5_+_162887516	72.457	NM_001142556 NM_001142557 NM_012484 NM_012485	HMMR	hyaluronan-mediated motility receptor (RHAMM)
chr1_+_154947166	72.274		CKS1B	CDC28 protein kinase regulatory subunit 1B
chr19_-_2328566	72.062	NM_016199	LSM7	LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_+_216974006	71.318	NM_021141	XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chr1_+_154947147	70.762		CKS1B	CDC28 protein kinase regulatory subunit 1B
chr19_+_47634133	70.295		SAE1	SUMO1 activating enzyme subunit 1
chr14_-_23058114	69.906	NM_001344	DAD1	defender against cell death 1
chr19_+_47634044	69.567	NM_001145713 NM_001145714 NM_005500	SAE1	SUMO1 activating enzyme subunit 1
chr3_+_150321065	69.519	NM_016275	SELT	selenoprotein T
chr10_-_16859408	69.468	NM_012425 NM_152724	RSU1	Ras suppressor protein 1
chr20_-_32699915	69.188		EIF2S2	eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr19_+_47634148	69.154		SAE1	SUMO1 activating enzyme subunit 1
chrX_-_16888175	66.288		RBBP7	retinoblastoma binding protein 7
chr19_-_2427874	66.148	NM_012458	TIMM13	translocase of inner mitochondrial membrane 13 homolog (yeast)
chr19_+_47634118	65.515		SAE1	SUMO1 activating enzyme subunit 1
chr1_+_154947116	65.483	NM_001826	CKS1B	CDC28 protein kinase regulatory subunit 1B
chr5_+_10250410	65.431		CCT5	chaperonin containing TCP1, subunit 5 (epsilon)
chr2_-_130939146	64.568	NM_001171083 NM_017751 NM_017951	SMPD4	sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
chr3_+_120315127	64.178	NM_001168331 NM_004547	NDUFB4	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
chr14_+_67827087	63.785		EIF2S1	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr3_+_120315176	63.154		NDUFB4	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
chrX_-_16888442	62.734		RBBP7	retinoblastoma binding protein 7
chr5_+_10250281	62.687	NM_012073	CCT5	chaperonin containing TCP1, subunit 5 (epsilon)
chr17_+_40761658	61.590		TUBG1	tubulin, gamma 1
chr12_+_131356640	61.401		RAN	RAN, member RAS oncogene family
chr5_+_10250440	60.829		CCT5	chaperonin containing TCP1, subunit 5 (epsilon)
chr4_-_1242742	59.960		CTBP1	C-terminal binding protein 1
chr5_-_133561745	59.305		PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme
chr19_+_17416476	59.290	NM_023937	MRPL34	mitochondrial ribosomal protein L34
chr11_-_77850633	59.278		ALG8	asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)
chr1_+_41445402	59.098		CTPS	CTP synthase
chr6_-_31774579	59.038		LSM2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_+_130939500	59.037	NM_025029	MZT2B	mitotic spindle organizing protein 2B
chr3_-_49066858	58.995	NM_000884	IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2
chr9_-_139378192	58.912		SEC16A	SEC16 homolog A (S. cerevisiae)
chr20_+_57556322	58.895		TH1L	TH1-like (Drosophila)
chrX_-_16887974	58.408	NM_001198719	RBBP7	retinoblastoma binding protein 7
chr2_+_190526124	58.398	NM_019048	ASNSD1	asparagine synthetase domain containing 1
chr17_+_40761357	58.397	NM_001070	TUBG1	tubulin, gamma 1
chr16_+_4475804	58.147	NM_001135110 NM_005147	DNAJA3	DnaJ (Hsp40) homolog, subfamily A, member 3
chr4_+_146019368	58.122		ABCE1	ATP-binding cassette, sub-family E (OABP), member 1
chr5_+_10250370	57.992		CCT5	chaperonin containing TCP1, subunit 5 (epsilon)
chr5_+_52095929	57.698		PELO	pelota homolog (Drosophila)
chr6_-_31774725	57.472	NM_021177	LSM2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr11_-_77850670	57.215		ALG8	asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)
chr11_-_77850687	57.131	NM_001007027 NM_024079	ALG8	asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)
chr14_-_102553344	57.108		HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1
chr19_+_59056017	56.936		TRIM28	tripartite motif containing 28
chr1_+_35734558	56.767	NM_005095	ZMYM4	zinc finger, MYM-type 4
chr20_+_25176333	56.681	NM_001114089 NM_001247	ENTPD6	ectonucleoside triphosphate diphosphohydrolase 6 (putative)
chr1_+_100731696	56.272	NM_001130841 NM_003729	RTCD1	RNA terminal phosphate cyclase domain 1
chr11_+_108535773	56.113	NM_004398	DDX10	DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr3_+_100428361	55.853	NM_001195478	TFG	TRK-fused gene
chr9_+_131451519	55.623		SET	SET nuclear oncogene
chr1_-_8939150	55.489	NM_001428	ENO1	enolase 1, (alpha)
chr19_+_8509869	55.467		HNRNPM	heterogeneous nuclear ribonucleoprotein M
chr5_+_10250403	55.345		CCT5	chaperonin containing TCP1, subunit 5 (epsilon)
chr17_-_3627073	55.281		ITGAE	integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
chr20_+_57556295	54.942	NM_198976	TH1L	TH1-like (Drosophila)
chr2_-_150444236	54.856		MMADHC	methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr19_-_55919324	54.540	NM_014501	UBE2S	ubiquitin-conjugating enzyme E2S
chr9_-_124921981	54.424		NDUFA8	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
chr6_-_42981656	54.169		MEA1	male-enhanced antigen 1
chr10_-_71993070	54.148	NM_021129	PPA1	pyrophosphatase (inorganic) 1
chr19_+_8509802	54.131	NM_005968 NM_031203	HNRNPM	heterogeneous nuclear ribonucleoprotein M
chr3_-_150320949	53.920		SERP1	stress-associated endoplasmic reticulum protein 1
chr17_+_3572089	53.659	NM_001014764 NM_031298	TMEM93	transmembrane protein 93
chr13_+_76123885	53.495	NM_006002	UCHL3	ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr1_+_91966365	53.012	NM_001134419 NM_003503	CDC7	cell division cycle 7 homolog (S. cerevisiae)
chr19_+_984316	52.934	NM_024100	WDR18	WD repeat domain 18
chr1_+_41445359	52.622		CTPS	CTP synthase
chr4_+_146019486	52.601		ABCE1	ATP-binding cassette, sub-family E (OABP), member 1
chr7_+_100027404	52.591		MEPCE	methylphosphate capping enzyme
chr19_-_10305600	52.559		DNMT1	DNA (cytosine-5-)-methyltransferase 1
chr14_+_67827042	52.553		EIF2S1	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr6_+_24667262	52.549	NM_001160094 NM_018473	ACOT13	acyl-CoA thioesterase 13
chr19_+_36236460	52.442	NM_172341	PSENEN	presenilin enhancer 2 homolog (C. elegans)
chr2_-_150444219	52.323		MMADHC	methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr21_-_33651324	52.148	NM_018944	MIS18A	MIS18 kinetochore protein homolog A (S. pombe)
chr16_+_67063035	52.039	NM_001755 NM_022845	CBFB	core-binding factor, beta subunit
chr19_+_531688	51.921	NM_004359	CDC34	cell division cycle 34 homolog (S. cerevisiae)
chr9_+_131451470	51.886	NM_003011	SET	SET nuclear oncogene
chr10_-_16859336	51.848		RSU1	Ras suppressor protein 1
chr4_-_1242882	51.736	NM_001012614 NM_001328	CTBP1	C-terminal binding protein 1
chr3_-_48647052	51.708		UQCRC1	ubiquinol-cytochrome c reductase core protein I
chr2_+_216974120	51.359		XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chr3_-_48647085	50.851	NM_003365	UQCRC1	ubiquinol-cytochrome c reductase core protein I
chr7_-_102119307	50.830	NM_006234	POLR2J	polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
chr3_-_112280764	50.749		ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)
chr10_+_99185977	50.738		PGAM1	phosphoglycerate mutase 1 (brain)
chr5_-_179050675	50.729	NM_005520	HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)
chr2_-_150444285	50.682	NM_015702	MMADHC	methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr3_-_49066813	50.593		IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2
chr6_+_32936400	50.587	NM_005104	BRD2	bromodomain containing 2
chr3_-_49066760	50.571		IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2
chr15_-_65477645	50.525		CLPX	ClpX caseinolytic peptidase X homolog (E. coli)
chr19_+_59055866	50.494		TRIM28	tripartite motif containing 28
chr5_+_218428	50.419		SDHA	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr20_+_55926144	50.368	NM_003610	RAE1	RAE1 RNA export 1 homolog (S. pombe)
chr4_+_57845095	50.143	NM_000938	POLR2B	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr17_-_47755340	50.110	NM_001007226 NM_001007227 NM_001007228 NM_001007229 NM_001007230 NM_003563	SPOP	speckle-type POZ protein
chr20_+_55926299	49.892		RAE1	RAE1 RNA export 1 homolog (S. pombe)
chr8_-_109260930	49.621		EIF3E	eukaryotic translation initiation factor 3, subunit E
chr2_+_101179395	49.607	NM_024065	PDCL3	phosducin-like 3
chr5_+_10250377	49.534		CCT5	chaperonin containing TCP1, subunit 5 (epsilon)
chr19_-_1095380	49.496	NM_002695	POLR2E	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
chr8_-_109260940	49.283	NM_001568	EIF3E	eukaryotic translation initiation factor 3, subunit E
chr19_-_14529853	49.100		DDX39A	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr4_+_57845057	48.978		POLR2B	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr19_+_8509594	48.852		HNRNPM	heterogeneous nuclear ribonucleoprotein M
chr5_-_179050635	48.401		HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)
chr19_-_1095316	48.395		POLR2E	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
chrX_-_129299680	48.258		AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1
chr1_+_100731797	48.059		RTCD1	RNA terminal phosphate cyclase domain 1
chr7_-_105752974	48.049	NM_006754	SYPL1	synaptophysin-like 1
chr14_-_102605974	47.683	NM_001017963	HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1
chr4_+_57845018	47.610		POLR2B	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr1_-_19536741	47.574	NM_020765	UBR4	ubiquitin protein ligase E3 component n-recognin 4
chr5_-_133561551	47.456		PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme
chr19_+_11071583	47.377	NM_001128844 NM_003072	SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr20_+_55926585	47.169	NM_001015885	RAE1	RAE1 RNA export 1 homolog (S. pombe)
chr7_-_42971730	46.864		PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2
chr2_+_216974101	46.853		XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chr11_+_65101224	46.756	NM_006268	DPF2	D4, zinc and double PHD fingers family 2
chr7_+_100303673	46.328	NM_005837	POP7	processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
chr19_-_1095373	46.212		POLR2E	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
chr2_-_132250050	45.912	NM_001085365	MZT2A	mitotic spindle organizing protein 2A
chr17_+_7210317	45.827	NM_001143760	EIF5A	eukaryotic translation initiation factor 5A
chr19_+_39421347	45.684	NM_033362	MRPS12	mitochondrial ribosomal protein S12
chr6_-_159065739	45.240	NM_006519	DYNLT1	dynein, light chain, Tctex-type 1
chrX_-_129299629	45.206		AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1
chr7_+_100027253	45.097	NM_019606	MEPCE	methylphosphate capping enzyme
chr17_+_35849997	44.742		DUSP14	dual specificity phosphatase 14
chr19_+_59055826	44.721	NM_005762	TRIM28	tripartite motif containing 28
chr8_+_145137496	44.535		GPAA1	glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)
chr2_+_86333304	44.435	NM_017952	PTCD3	Pentatricopeptide repeat domain 3
chr12_+_110906203	44.361	NM_013300	C12orf24	chromosome 12 open reading frame 24
chr2_+_242255365	44.303		SEPT2	septin 2
chr12_-_27091207	44.111	NM_018164	ASUN	asunder, spermatogenesis regulator homolog (Drosphila)
chr1_-_155231941	44.048		SCAMP3	secretory carrier membrane protein 3
chr13_+_27998614	43.974	NM_002097	GTF3A	general transcription factor IIIA
chr9_+_131451823	43.887		SET	SET nuclear oncogene
chr3_+_133292404	43.838	NM_001134422 NM_017548	CDV3	CDV3 homolog (mouse)
chr17_-_56084611	43.766		SRSF1	serine/arginine-rich splicing factor 1
chr21_-_38445389	43.519	NM_153682	PIGP	phosphatidylinositol glycan anchor biosynthesis, class P
chr19_-_10305645	43.374	NM_001130823 NM_001379	DNMT1	DNA (cytosine-5-)-methyltransferase 1
chr1_+_91966653	43.352	NM_001134420	CDC7	cell division cycle 7 homolog (S. cerevisiae)
chr1_+_167189948	43.341	NM_001198786 NM_002697	POU2F1	POU class 2 homeobox 1
chr12_-_27090877	43.197		ASUN	asunder, spermatogenesis regulator homolog (Drosphila)
chr19_+_39109684	43.116	NM_013234	EIF3K	eukaryotic translation initiation factor 3, subunit K
chr17_+_35849950	42.807	NM_007026	DUSP14	dual specificity phosphatase 14
chr19_+_11071792	42.774	NM_001128849	SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr18_-_54305657	42.548		TXNL1	thioredoxin-like 1
chr3_-_107809754	42.524	NM_001777 NM_198793	CD47	CD47 molecule
chr10_+_60028885	42.389	NM_018464	CISD1	CDGSH iron sulfur domain 1
chr17_+_7155371	42.375	NM_203415 NM_015362 NM_203413 NM_203414	C17orf81	chromosome 17 open reading frame 81
chr15_-_90777191	42.366	NM_006384	CIB1	calcium and integrin binding 1 (calmyrin)
chr14_-_54908035	42.297	NM_005776	CNIH	cornichon homolog (Drosophila)
chr21_-_38444814	42.286	NM_153681	PIGP	phosphatidylinositol glycan anchor biosynthesis, class P
chr2_-_198364997	42.153	NM_199440	HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr3_-_182698291	42.147	NM_020640	DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)
chr14_-_102553386	42.070	NM_005348	HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1
chr17_+_7486964	41.998	NM_004870	MPDU1	mannose-P-dolichol utilization defect 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.77	5.24e-56	GO:0044260	cellular macromolecule metabolic process
1.58	1.03e-55	GO:0044237	cellular metabolic process
1.63	2.47e-44	GO:0043170	macromolecule metabolic process
1.46	2.23e-43	GO:0008152	metabolic process
2.08	4.01e-43	GO:0090304	nucleic acid metabolic process
1.93	3.36e-42	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.48	3.86e-39	GO:0044238	primary metabolic process
1.79	3.45e-37	GO:0034641	cellular nitrogen compound metabolic process
1.77	1.45e-36	GO:0006807	nitrogen compound metabolic process
1.24	3.20e-34	GO:0009987	cellular process
2.02	1.07e-30	GO:0010467	gene expression
2.02	7.52e-29	GO:0016070	RNA metabolic process
2.71	6.71e-25	GO:0006396	RNA processing
2.76	1.14e-21	GO:0016071	mRNA metabolic process
1.70	1.41e-21	GO:0044267	cellular protein metabolic process
1.66	2.54e-21	GO:0071841	cellular component organization or biogenesis at cellular level
3.34	3.20e-20	GO:0008380	RNA splicing
1.89	4.63e-20	GO:0006996	organelle organization
3.90	8.78e-20	GO:0000375	RNA splicing, via transesterification reactions
3.88	5.37e-19	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
3.88	5.37e-19	GO:0000398	nuclear mRNA splicing, via spliceosome
1.63	2.01e-18	GO:0071842	cellular component organization at cellular level
1.83	2.23e-18	GO:0034645	cellular macromolecule biosynthetic process
2.93	2.69e-18	GO:0006397	mRNA processing
1.82	5.25e-18	GO:0009059	macromolecule biosynthetic process
1.52	7.62e-18	GO:0071840	cellular component organization or biogenesis
2.50	3.19e-17	GO:0000278	mitotic cell cycle
2.35	4.12e-17	GO:0022403	cell cycle phase
2.21	3.93e-16	GO:0046907	intracellular transport
1.50	8.00e-16	GO:0016043	cellular component organization
2.03	8.19e-16	GO:0007049	cell cycle
2.17	1.67e-15	GO:0022402	cell cycle process
1.60	6.68e-15	GO:0044249	cellular biosynthetic process
1.52	1.08e-14	GO:0019538	protein metabolic process
1.55	3.17e-13	GO:0009058	biosynthetic process
1.83	4.36e-13	GO:0051641	cellular localization
2.28	7.27e-13	GO:0006259	DNA metabolic process
1.87	2.80e-12	GO:0051649	establishment of localization in cell
2.21	4.94e-12	GO:0051276	chromosome organization
3.93	5.97e-12	GO:0006403	RNA localization
2.46	6.73e-12	GO:0000279	M phase
3.97	8.90e-12	GO:0050657	nucleic acid transport
3.97	8.90e-12	GO:0050658	RNA transport
3.97	8.90e-12	GO:0051236	establishment of RNA localization
1.99	2.55e-11	GO:0033554	cellular response to stress
4.02	5.72e-11	GO:0051028	mRNA transport
2.66	1.62e-10	GO:0006412	translation
2.68	1.84e-10	GO:0000087	M phase of mitotic cell cycle
3.50	5.67e-10	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
4.84	6.84e-10	GO:0006405	RNA export from nucleus
2.63	7.22e-10	GO:0048285	organelle fission
2.21	9.86e-10	GO:0006974	response to DNA damage stimulus
2.34	2.03e-09	GO:0016032	viral reproduction
2.59	5.13e-09	GO:0000280	nuclear division
2.59	5.13e-09	GO:0007067	mitosis
4.18	9.77e-09	GO:0051168	nuclear export
1.67	1.55e-08	GO:0033036	macromolecule localization
2.16	1.87e-08	GO:0034621	cellular macromolecular complex subunit organization
2.52	1.93e-08	GO:0051329	interphase of mitotic cell cycle
3.46	2.18e-08	GO:0045333	cellular respiration
2.02	2.31e-08	GO:0009057	macromolecule catabolic process
2.40	2.53e-08	GO:0006281	DNA repair
2.10	2.74e-08	GO:0044265	cellular macromolecule catabolic process
2.99	3.73e-08	GO:0051169	nuclear transport
2.47	4.27e-08	GO:0051325	interphase
1.68	7.79e-08	GO:0044085	cellular component biogenesis
2.95	9.25e-08	GO:0006913	nucleocytoplasmic transport
1.82	9.58e-08	GO:0015031	protein transport
4.64	1.02e-07	GO:0006406	mRNA export from nucleus
1.80	1.54e-07	GO:0045184	establishment of protein localization
1.69	4.79e-07	GO:0008104	protein localization
2.27	7.05e-07	GO:0051301	cell division
1.65	7.90e-07	GO:0044248	cellular catabolic process
1.72	8.40e-07	GO:0032774	RNA biosynthetic process
1.78	9.82e-07	GO:0043933	macromolecular complex subunit organization
1.48	1.28e-06	GO:0043412	macromolecule modification
2.66	1.40e-06	GO:0071843	cellular component biogenesis at cellular level
3.60	1.40e-06	GO:0022904	respiratory electron transport chain
2.37	1.73e-06	GO:0006366	transcription from RNA polymerase II promoter
2.69	2.55e-06	GO:0022613	ribonucleoprotein complex biogenesis
2.17	6.66e-06	GO:0034622	cellular macromolecular complex assembly
1.47	8.14e-06	GO:0006464	protein modification process
4.85	3.28e-05	GO:0006413	translational initiation
2.11	3.29e-05	GO:0044419	interspecies interaction between organisms
1.74	4.60e-05	GO:0071844	cellular component assembly at cellular level
1.94	6.95e-05	GO:0006325	chromatin organization
1.50	7.84e-05	GO:0009056	catabolic process
3.69	9.87e-05	GO:0006200	ATP catabolic process
1.75	9.90e-05	GO:0065003	macromolecular complex assembly
1.79	1.11e-04	GO:0051726	regulation of cell cycle
2.24	1.28e-04	GO:0034660	ncRNA metabolic process
1.59	1.42e-04	GO:0022607	cellular component assembly
2.45	1.54e-04	GO:0006457	protein folding
1.65	1.65e-04	GO:0006351	transcription, DNA-dependent
1.86	1.83e-04	GO:0070727	cellular macromolecule localization
1.85	2.94e-04	GO:0034613	cellular protein localization
2.76	3.71e-04	GO:0022900	electron transport chain
3.62	5.80e-04	GO:0031124	mRNA 3'-end processing
1.95	6.14e-04	GO:0006886	intracellular protein transport
2.88	9.67e-04	GO:0000086	G2/M transition of mitotic cell cycle
2.02	1.02e-03	GO:0070647	protein modification by small protein conjugation or removal
3.96	1.12e-03	GO:0007051	spindle organization
3.26	1.16e-03	GO:0000956	nuclear-transcribed mRNA catabolic process
3.61	1.21e-03	GO:0006368	transcription elongation from RNA polymerase II promoter
2.16	1.26e-03	GO:0016567	protein ubiquitination
1.29	1.32e-03	GO:0051234	establishment of localization
1.91	1.65e-03	GO:0006091	generation of precursor metabolites and energy
2.10	1.73e-03	GO:0032446	protein modification by small protein conjugation
2.10	2.37e-03	GO:0015980	energy derivation by oxidation of organic compounds
1.94	2.56e-03	GO:0016568	chromatin modification
2.32	2.77e-03	GO:0034470	ncRNA processing
2.45	3.06e-03	GO:0022415	viral reproductive process
2.48	3.08e-03	GO:0000226	microtubule cytoskeleton organization
2.07	3.34e-03	GO:0010608	posttranscriptional regulation of gene expression
4.08	3.49e-03	GO:0006369	termination of RNA polymerase II transcription
1.94	3.51e-03	GO:0010564	regulation of cell cycle process
1.57	3.71e-03	GO:0008219	cell death
3.26	3.83e-03	GO:0006302	double-strand break repair
1.28	3.92e-03	GO:0006810	transport
3.03	4.70e-03	GO:0006402	mRNA catabolic process
1.56	4.72e-03	GO:0016265	death
4.50	4.91e-03	GO:0000245	spliceosome assembly
2.38	5.59e-03	GO:0006417	regulation of translation
3.73	6.15e-03	GO:0006119	oxidative phosphorylation
2.51	7.91e-03	GO:0007005	mitochondrion organization
2.51	7.91e-03	GO:0019058	viral infectious cycle
1.50	8.65e-03	GO:0032268	regulation of cellular protein metabolic process
1.68	8.72e-03	GO:0071822	protein complex subunit organization
2.16	9.11e-03	GO:0009203	ribonucleoside triphosphate catabolic process
2.16	9.11e-03	GO:0009207	purine ribonucleoside triphosphate catabolic process
1.92	9.65e-03	GO:0051603	proteolysis involved in cellular protein catabolic process
2.15	1.03e-02	GO:0009146	purine nucleoside triphosphate catabolic process
2.06	1.05e-02	GO:0051248	negative regulation of protein metabolic process
2.39	1.06e-02	GO:0071103	DNA conformation change
2.52	1.08e-02	GO:0046034	ATP metabolic process
1.53	1.10e-02	GO:0010605	negative regulation of macromolecule metabolic process
1.92	1.19e-02	GO:0043632	modification-dependent macromolecule catabolic process
1.60	1.23e-02	GO:0012501	programmed cell death
3.04	1.24e-02	GO:0031123	RNA 3'-end processing
2.55	1.26e-02	GO:0042254	ribosome biogenesis
1.86	1.32e-02	GO:0030163	protein catabolic process
2.85	1.34e-02	GO:0006364	rRNA processing
3.90	1.45e-02	GO:0000070	mitotic sister chromatid segregation
2.12	1.47e-02	GO:0009143	nucleoside triphosphate catabolic process
2.12	1.47e-02	GO:0009154	purine ribonucleotide catabolic process
1.88	1.70e-02	GO:0044257	cellular protein catabolic process
2.89	1.79e-02	GO:0000236	mitotic prometaphase
1.95	1.83e-02	GO:0009199	ribonucleoside triphosphate metabolic process
2.10	1.86e-02	GO:0009261	ribonucleotide catabolic process
2.66	1.90e-02	GO:0007059	chromosome segregation
2.96	1.92e-02	GO:0006839	mitochondrial transport
2.05	1.96e-02	GO:0032269	negative regulation of cellular protein metabolic process
2.01	2.02e-02	GO:0009166	nucleotide catabolic process
1.23	2.05e-02	GO:0051179	localization
1.90	2.14e-02	GO:0019941	modification-dependent protein catabolic process
1.31	2.28e-02	GO:0048523	negative regulation of cellular process
1.89	2.35e-02	GO:0033043	regulation of organelle organization
1.46	2.47e-02	GO:0051246	regulation of protein metabolic process
2.30	2.49e-02	GO:0010498	proteasomal protein catabolic process
2.30	2.49e-02	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
2.68	2.58e-02	GO:0006414	translational elongation
1.90	2.63e-02	GO:0006511	ubiquitin-dependent protein catabolic process
3.49	3.09e-02	GO:0050434	positive regulation of viral transcription
1.88	3.17e-02	GO:0009150	purine ribonucleotide metabolic process
4.15	3.24e-02	GO:0009060	aerobic respiration
2.01	3.37e-02	GO:0072523	purine-containing compound catabolic process
2.70	3.50e-02	GO:0016072	rRNA metabolic process
1.57	3.56e-02	GO:0006915	apoptosis
1.92	3.67e-02	GO:0009205	purine ribonucleoside triphosphate metabolic process
3.63	3.67e-02	GO:0000819	sister chromatid segregation
2.37	3.69e-02	GO:0006310	DNA recombination
2.56	3.79e-02	GO:0006401	RNA catabolic process
1.85	4.07e-02	GO:0009259	ribonucleotide metabolic process
2.01	4.14e-02	GO:0006195	purine nucleotide catabolic process
1.89	4.36e-02	GO:0009141	nucleoside triphosphate metabolic process
1.90	4.88e-02	GO:0009144	purine nucleoside triphosphate metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.33	4.35e-77	GO:0044424	intracellular part
1.31	1.02e-72	GO:0005622	intracellular
1.45	7.27e-71	GO:0043227	membrane-bounded organelle
1.45	9.47e-71	GO:0043231	intracellular membrane-bounded organelle
1.40	1.03e-70	GO:0043229	intracellular organelle
1.40	3.96e-70	GO:0043226	organelle
1.65	1.15e-59	GO:0044446	intracellular organelle part
1.64	1.04e-58	GO:0044422	organelle part
2.13	1.87e-48	GO:0044428	nuclear part
1.40	6.45e-47	GO:0005737	cytoplasm
1.57	1.93e-46	GO:0005634	nucleus
1.76	4.05e-42	GO:0032991	macromolecular complex
1.95	3.33e-38	GO:0031974	membrane-enclosed lumen
1.97	7.74e-38	GO:0070013	intracellular organelle lumen
1.94	3.01e-36	GO:0043233	organelle lumen
2.07	1.96e-35	GO:0031981	nuclear lumen
1.45	3.26e-32	GO:0044444	cytoplasmic part
2.19	3.47e-30	GO:0005654	nucleoplasm
1.79	3.44e-23	GO:0005829	cytosol
1.62	3.76e-22	GO:0043234	protein complex
2.73	9.55e-22	GO:0030529	ribonucleoprotein complex
1.57	2.45e-17	GO:0043228	non-membrane-bounded organelle
1.57	2.45e-17	GO:0043232	intracellular non-membrane-bounded organelle
1.82	7.84e-15	GO:0005739	mitochondrion
2.17	1.23e-14	GO:0031967	organelle envelope
2.47	3.33e-14	GO:0044427	chromosomal part
2.13	5.34e-14	GO:0031975	envelope
1.08	1.53e-13	GO:0044464	cell part
1.08	1.61e-13	GO:0005623	cell
2.29	2.11e-13	GO:0005694	chromosome
3.80	1.87e-11	GO:0044455	mitochondrial membrane part
2.03	1.00e-10	GO:0044429	mitochondrial part
1.89	1.58e-08	GO:0044451	nucleoplasm part
2.08	1.82e-08	GO:0005730	nucleolus
2.87	3.15e-08	GO:0005819	spindle
1.44	2.66e-07	GO:0031090	organelle membrane
2.25	2.85e-07	GO:0019866	organelle inner membrane
3.07	3.60e-07	GO:0005681	spliceosomal complex
2.30	4.02e-07	GO:0005743	mitochondrial inner membrane
2.06	4.78e-07	GO:0031966	mitochondrial membrane
1.83	6.71e-07	GO:0015630	microtubule cytoskeleton
2.02	6.82e-07	GO:0005740	mitochondrial envelope
2.43	1.51e-06	GO:0005635	nuclear envelope
3.80	1.05e-05	GO:0000922	spindle pole
3.80	1.05e-05	GO:0070469	respiratory chain
2.33	1.69e-05	GO:0000785	chromatin
2.73	2.50e-05	GO:0000775	chromosome, centromeric region
2.08	2.65e-05	GO:0005815	microtubule organizing center
3.30	5.37e-05	GO:0046930	pore complex
3.74	6.27e-05	GO:0005746	mitochondrial respiratory chain
2.48	9.16e-05	GO:0044454	nuclear chromosome part
3.47	1.28e-04	GO:0005643	nuclear pore
2.28	1.67e-04	GO:0000228	nuclear chromosome
3.11	1.80e-04	GO:0000776	kinetochore
3.18	3.71e-04	GO:0071013	catalytic step 2 spliceosome
2.19	5.39e-04	GO:0005813	centrosome
3.17	1.23e-03	GO:0000777	condensed chromosome kinetochore
2.14	1.37e-03	GO:0016604	nuclear body
2.46	1.56e-03	GO:0000793	condensed chromosome
2.96	3.78e-03	GO:0000779	condensed chromosome, centromeric region
2.19	3.90e-03	GO:0005840	ribosome
1.96	7.41e-03	GO:0005759	mitochondrial matrix
4.56	1.30e-02	GO:0044452	nucleolar part
3.23	1.73e-02	GO:0034708	methyltransferase complex
3.23	1.73e-02	GO:0035097	histone methyltransferase complex
1.34	1.81e-02	GO:0012505	endomembrane system
2.38	1.90e-02	GO:0016607	nuclear speck
6.14	2.18e-02	GO:0005665	DNA-directed RNA polymerase II, core complex
3.45	2.68e-02	GO:0016469	proton-transporting two-sector ATPase complex
2.22	3.45e-02	GO:0000151	ubiquitin ligase complex
6.85	3.59e-02	GO:0005868	cytoplasmic dynein complex
2.19	4.45e-02	GO:0031965	nuclear membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.49	2.94e-55	GO:0005515	protein binding
2.48	7.50e-27	GO:0003723	RNA binding
1.17	4.00e-22	GO:0005488	binding
1.43	1.35e-12	GO:0003676	nucleic acid binding
1.54	1.60e-12	GO:0000166	nucleotide binding
1.28	2.84e-10	GO:0003824	catalytic activity
1.49	8.98e-06	GO:0005524	ATP binding
1.48	9.73e-06	GO:0030554	adenyl nucleotide binding
1.71	9.82e-06	GO:0016462	pyrophosphatase activity
1.48	1.05e-05	GO:0032559	adenyl ribonucleotide binding
1.70	1.23e-05	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.69	1.53e-05	GO:0016817	hydrolase activity, acting on acid anhydrides
3.03	1.65e-05	GO:0051082	unfolded protein binding
1.42	1.85e-05	GO:0035639	purine ribonucleoside triphosphate binding
1.41	2.88e-05	GO:0032553	ribonucleotide binding
1.41	2.88e-05	GO:0032555	purine ribonucleotide binding
1.41	2.91e-05	GO:0017076	purine nucleotide binding
1.66	1.19e-04	GO:0017111	nucleoside-triphosphatase activity
3.24	1.86e-04	GO:0008135	translation factor activity, nucleic acid binding
4.04	2.06e-04	GO:0003743	translation initiation factor activity
2.83	3.73e-04	GO:0016779	nucleotidyltransferase activity
1.94	6.64e-04	GO:0016887	ATPase activity
1.76	1.99e-03	GO:0016874	ligase activity
3.99	2.68e-03	GO:0003899	DNA-directed RNA polymerase activity
3.99	2.68e-03	GO:0034062	RNA polymerase activity
11.41	3.50e-03	GO:0017070	U6 snRNA binding
2.15	8.42e-03	GO:0003682	chromatin binding
1.92	1.30e-02	GO:0016881	acid-amino acid ligase activity
3.20	1.40e-02	GO:0003697	single-stranded DNA binding
2.10	1.86e-02	GO:0043566	structure-specific DNA binding
1.85	1.96e-02	GO:0016879	ligase activity, forming carbon-nitrogen bonds
2.00	2.00e-02	GO:0004842	ubiquitin-protein ligase activity
2.21	2.71e-02	GO:0004518	nuclease activity
1.94	3.32e-02	GO:0019787	small conjugating protein ligase activity
2.25	3.49e-02	GO:0004386	helicase activity