Motif ID: PBX1.p2

Z-value: 1.691


Transcription factors associated with PBX1.p2:

Gene SymbolEntrez IDGene Name
PBX1 5087 pre-B-cell leukemia homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PBX1chr1_+_164528914-0.468.5e-13Click!


Activity profile for motif PBX1.p2.

activity profile for motif PBX1.p2


Sorted Z-values histogram for motif PBX1.p2

Sorted Z-values for motif PBX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PBX1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_28241233 39.561 NM_002946
RPA2
replication protein A2, 32kDa
chr5_+_162864571 39.419 NM_004060
NM_199246
CCNG1

cyclin G1

chr9_+_140135698 34.638 NM_006088
TUBB4B
tubulin, beta 4B class IVb
chrX_+_119737743 34.563 NM_014060
MCTS1
malignant T cell amplified sequence 1
chr9_+_140135738 32.071 TUBB4B
tubulin, beta 4B class IVb
chr17_+_8191814 32.011 NM_001177801
NM_001177802
NM_016492
RANGRF


RAN guanine nucleotide release factor


chr7_-_7680048 28.893 RPA3
replication protein A3, 14kDa
chr4_-_174255454 27.727 NM_001130688
NM_002129
HMGB2

high mobility group box 2

chrX_+_119737905 27.551 MCTS1
malignant T cell amplified sequence 1
chr9_+_140135742 26.285 TUBB4B
tubulin, beta 4B class IVb
chrX_+_119737984 25.573 MCTS1
malignant T cell amplified sequence 1
chr12_+_64803741 25.371 XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr3_-_32544358 24.483 NM_017801
CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chr12_+_49658862 23.896 NM_032704
TUBA1C
tubulin, alpha 1c
chr3_+_172468469 23.418 ECT2
epithelial cell transforming sequence 2 oncogene
chr6_+_111195986 23.367 NM_001634
NM_001033059
AMD1

adenosylmethionine decarboxylase 1

chr6_-_75965845 22.639 TMEM30A
transmembrane protein 30A
chr1_-_28240953 22.607 RPA2
replication protein A2, 32kDa
chr12_+_49658865 22.297 TUBA1C
tubulin, alpha 1c
chr2_+_216986817 21.728 XRCC5
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chrX_+_123234462 21.067 STAG2
stromal antigen 2
chr5_-_89705477 20.806 NM_004365
CETN3
centrin, EF-hand protein, 3
chr15_-_64673569 20.598 NM_001029989
NM_014736
KIAA0101

KIAA0101

chr10_+_102123420 20.238


chr6_-_27114577 19.844 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr17_-_38821286 19.509 NM_152349
KRT222
keratin 222
chr6_+_149721494 19.205 NM_001002255
SUMO4
SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae)
chr20_+_44441334 18.793 UBE2C
ubiquitin-conjugating enzyme E2C
chr6_+_27114860 18.726 NM_080596
HIST1H2AH
histone cluster 1, H2ah
chr14_+_64971504 18.509 ZBTB1
zinc finger and BTB domain containing 1
chr5_+_44808967 18.489 NM_016640
MRPS30
mitochondrial ribosomal protein S30
chr10_+_14880335 17.080 HSPA14
heat shock 70kDa protein 14
chr3_-_129158675 17.074 MBD4
methyl-CpG binding domain protein 4
chr3_-_32544319 16.944 CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chr3_-_129158849 16.754 NM_003925
MBD4
methyl-CpG binding domain protein 4
chr3_-_129158779 16.686 MBD4
methyl-CpG binding domain protein 4
chr3_-_33481877 16.463 NM_001128161
UBP1
upstream binding protein 1 (LBP-1a)
chr1_+_155278727 16.421 FDPS
farnesyl diphosphate synthase
chr3_-_33481862 16.149 NM_001128160
NM_014517
UBP1

upstream binding protein 1 (LBP-1a)

chr19_+_14640413 15.973 TECR
trans-2,3-enoyl-CoA reductase
chr1_+_155278677 15.937 NM_001135821
FDPS
farnesyl diphosphate synthase
chr10_+_14880343 15.874 HSPA14
heat shock 70kDa protein 14
chr3_+_38206968 15.805 NM_005109
OXSR1
oxidative-stress responsive 1
chr1_-_115268890 15.203 CSDE1
cold shock domain containing E1, RNA-binding
chr19_+_54619149 15.115 PRPF31
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
chr3_+_156394452 14.967 NM_001184718
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr3_+_179280738 14.858 ACTL6A
actin-like 6A
chr8_-_101965554 14.837 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr5_-_179044835 14.764 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr13_+_53035227 14.732 CKAP2
cytoskeleton associated protein 2
chr10_+_14880137 14.528 NM_016299
HSPA14
heat shock 70kDa protein 14
chr5_+_145826866 14.415 NM_001040006
NM_006706
TCERG1

transcription elongation regulator 1

chr8_-_101965096 14.375 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr12_-_120638894 14.247 RPLP0
ribosomal protein, large, P0
chr7_-_140179224 14.197 MKRN1
makorin ring finger protein 1
chr20_+_44441247 14.104 NM_007019
NM_181799
NM_181800
NM_181802
NM_181803
UBE2C




ubiquitin-conjugating enzyme E2C




chr19_+_14640406 13.656 TECR
trans-2,3-enoyl-CoA reductase
chr2_-_47134945 13.253 MCFD2
multiple coagulation factor deficiency 2
chr12_-_120638909 13.023 RPLP0
ribosomal protein, large, P0
chr8_-_25315941 12.622 NM_017634
KCTD9
potassium channel tetramerisation domain containing 9
chr1_+_151227209 12.507 PSMD4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
chr11_+_95523608 12.426 NM_001243776
NM_001243777
NM_014679
CEP57


centrosomal protein 57kDa


chr19_+_41770273 12.285 HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr2_-_200322699 12.135 NM_001172509
SATB2
SATB homeobox 2
chr19_+_14640403 12.055 TECR
trans-2,3-enoyl-CoA reductase
chr20_-_45976626 11.874 ZMYND8
zinc finger, MYND-type containing 8
chr3_+_179280746 11.816 ACTL6A
actin-like 6A
chr14_+_23938883 11.722 NM_001042635
NM_015514
NGDN

neuroguidin, EIF4E binding protein

chr6_+_26104103 11.716 NM_003542
HIST2H4B
HIST1H4C
histone cluster 2, H4b
histone cluster 1, H4c
chr8_+_107738239 11.493 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr3_-_148804122 11.413 NM_003071
NM_139048
HLTF

helicase-like transcription factor

chr14_-_54908035 11.305 NM_005776
CNIH
cornichon homolog (Drosophila)
chr7_-_148725764 11.294 NM_004911
PDIA4
protein disulfide isomerase family A, member 4
chr5_+_43602738 11.278 NM_012343
NNT
nicotinamide nucleotide transhydrogenase
chr20_+_30326903 11.249 NM_012112
TPX2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr19_+_14640363 10.494 NM_138501
TECR
trans-2,3-enoyl-CoA reductase
chr5_+_151151514 10.464 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr1_-_149399159 10.288 NM_001024599
HIST2H2BF
histone cluster 2, H2bf
chr1_+_151227188 10.282 NM_002810
PSMD4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
chr3_+_179280686 10.282 NM_004301
NM_177989
NM_178042
ACTL6A


actin-like 6A


chr1_-_3713048 10.212 NM_020710
LRRC47
leucine rich repeat containing 47
chr12_-_121790165 10.201 ANAPC5
anaphase promoting complex subunit 5
chr5_+_43603216 9.825 NM_182977
NNT
nicotinamide nucleotide transhydrogenase
chr7_-_140179133 9.776 MKRN1
makorin ring finger protein 1
chr22_-_43411129 9.721 PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr22_-_43411156 9.652 NM_001184970
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr7_-_148725731 9.363 PDIA4
protein disulfide isomerase family A, member 4
chr1_+_35851101 9.338 ZMYM4
zinc finger, MYM-type 4
chr12_+_28410132 9.328 NM_018318
CCDC91
coiled-coil domain containing 91
chr11_+_67798077 9.251 NM_002496
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr5_+_43603312 9.209 NNT
nicotinamide nucleotide transhydrogenase
chr8_+_98788014 9.165 LAPTM4B
lysosomal protein transmembrane 4 beta
chr14_-_55658205 8.970 NM_001146015
NM_014750
DLGAP5

discs, large (Drosophila) homolog-associated protein 5

chr3_+_136581007 8.832 NM_006153
NCK1
NCK adaptor protein 1
chr1_+_145663156 8.625 RNF115
ring finger protein 115
chr1_+_155278538 8.569 NM_001135822
NM_001242824
NM_001242825
NM_002004
FDPS



farnesyl diphosphate synthase



chrX_-_10645726 8.527 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr19_+_54619114 8.351 PRPF31
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
chr2_-_219134846 8.332 AAMP
angio-associated, migratory cell protein
chr1_+_149858466 8.319 NM_003517
HIST2H2AC
histone cluster 2, H2ac
chr1_+_32645322 8.311 NM_175852
TXLNA
taxilin alpha
chr2_+_171784947 8.248 NM_001201428
NM_015530
GORASP2

golgi reassembly stacking protein 2, 55kDa

chr1_-_241683060 8.012 NM_000143
FH
fumarate hydratase
chrX_-_23761396 7.960 NM_001033583
NM_001037171
ACOT9

acyl-CoA thioesterase 9

chr12_-_121790141 7.936 ANAPC5
anaphase promoting complex subunit 5
chr19_+_41770285 7.872 HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr7_-_7758237 7.867 NM_002947
RPA3
replication protein A3, 14kDa
chr19_-_39881631 7.740 NM_019088
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr3_+_171757432 7.727 FNDC3B
fibronectin type III domain containing 3B
chr12_-_56679729 7.667 CS
citrate synthase
chr1_-_42801529 7.662 NM_001198850
FOXJ3
forkhead box J3
chrX_+_70503496 7.653 NONO
non-POU domain containing, octamer-binding
chr1_-_241683011 7.632 FH
fumarate hydratase
chr5_+_151151462 7.575 NM_005754
NM_198395
G3BP1

GTPase activating protein (SH3 domain) binding protein 1

chr12_+_21168629 7.529 NM_001009562
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr16_-_58663734 7.499 CNOT1
CCR4-NOT transcription complex, subunit 1
chr3_+_136581074 7.474 NCK1
NCK adaptor protein 1
chr1_-_156308047 7.468 CCT3
chaperonin containing TCP1, subunit 3 (gamma)
chr2_+_12856813 7.443 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chr12_-_121790240 7.438 NM_016237
ANAPC5
anaphase promoting complex subunit 5
chr19_+_2269515 7.429 NM_004152
OAZ1
SPPL2B
ornithine decarboxylase antizyme 1
signal peptide peptidase-like 2B
chr9_+_91926109 7.423 NM_001827
CKS2
CDC28 protein kinase regulatory subunit 2
chr11_+_95523809 7.417 CEP57
centrosomal protein 57kDa
chr19_+_49375679 7.416 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr1_+_236557643 7.385 NM_145861
EDARADD
EDAR-associated death domain
chr16_+_69220940 7.337 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr4_-_48782281 7.328 NM_015030
FRYL
FRY-like
chr5_+_179132676 7.289 CANX
calnexin
chr1_+_214776494 7.275 NM_016343
CENPF
centromere protein F, 350/400kDa (mitosin)
chr3_+_136649316 7.262 NM_001190796
NCK1
NCK adaptor protein 1
chr19_-_14247400 7.244 NM_018154
ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr19_+_49375677 7.230 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr6_-_42713822 7.201 TBCC
tubulin folding cofactor C
chr12_-_120638912 7.201 NM_001002
NM_053275
RPLP0

ribosomal protein, large, P0

chr3_-_160283166 7.184 KPNA4
karyopherin alpha 4 (importin alpha 3)
chr19_-_14640048 7.181 DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr2_-_219134865 7.155 NM_001087
AAMP
angio-associated, migratory cell protein
chr17_-_29151724 7.150 NM_015986
CRLF3
cytokine receptor-like factor 3
chr17_-_29151638 7.143 CRLF3
cytokine receptor-like factor 3
chr19_+_2269526 7.106 OAZ1
ornithine decarboxylase antizyme 1
chr9_+_79968344 7.029 VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr12_-_14956408 7.006 WBP11
WW domain binding protein 11
chr5_+_151151516 6.976 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr4_+_83956238 6.956 NM_016129
COPS4
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
chr2_-_219134795 6.905 AAMP
angio-associated, migratory cell protein
chr11_-_57195052 6.904 NM_017611
SLC43A3
solute carrier family 43, member 3
chr11_+_69467210 6.853 CCND1
cyclin D1
chr19_+_49375638 6.845 NM_014330
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr2_-_61765394 6.826 NM_003400
XPO1
exportin 1 (CRM1 homolog, yeast)
chrX_+_70503469 6.725 NONO
non-POU domain containing, octamer-binding
chr6_+_160183510 6.682 ACAT2
acetyl-CoA acetyltransferase 2
chrX_-_107334749 6.666 NM_002814
NM_170750
PSMD10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chr2_+_191745547 6.657 GLS
glutaminase
chr14_-_75530716 6.655 NM_001107
NM_203488
ACYP1

acylphosphatase 1, erythrocyte (common) type

chr17_+_73663398 6.650 NM_013260
SAP30BP
SAP30 binding protein
chr4_-_72649734 6.583 NM_000583
GC
group-specific component (vitamin D binding protein)
chrX_+_47004657 6.553 RBM10
RNA binding motif protein 10
chr19_-_18433847 6.539 LSM4
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chrX_+_70503512 6.404 NONO
non-POU domain containing, octamer-binding
chr1_-_156307971 6.395 CCT3
chaperonin containing TCP1, subunit 3 (gamma)
chr19_+_41770057 6.317 NM_007040
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chrX_+_47004663 6.295 RBM10
RNA binding motif protein 10
chr9_+_131447364 6.260 NM_001248000
SET
SET nuclear oncogene
chr2_-_174829951 6.232 SP3
Sp3 transcription factor
chrX_+_47004676 6.210 RBM10
RNA binding motif protein 10
chrX_+_47004693 6.200 RBM10
RNA binding motif protein 10
chr6_-_42713837 6.173 NM_003192
TBCC
tubulin folding cofactor C
chr18_+_77866914 6.173 NM_014913
ADNP2
ADNP homeobox 2
chr19_+_2269529 6.117 OAZ1
ornithine decarboxylase antizyme 1
chr17_-_46622274 6.032 NM_002145
HOXB2
homeobox B2
chrX_+_47004665 6.029 RBM10
RNA binding motif protein 10
chr15_+_59397276 6.027 NM_004701
CCNB2
cyclin B2
chrX_+_47004633 5.940 RBM10
RNA binding motif protein 10
chr20_+_44441671 5.912 NM_181801
UBE2C
ubiquitin-conjugating enzyme E2C
chr12_-_14956367 5.904 NM_016312
WBP11
WW domain binding protein 11
chr12_-_120315074 5.896 NM_001206999
NM_007174
CIT

citron (rho-interacting, serine/threonine kinase 21)

chr3_-_160283071 5.880 KPNA4
karyopherin alpha 4 (importin alpha 3)
chrX_+_47004609 5.818 NM_001204466
NM_001204467
NM_001204468
NM_005676
NM_152856
RBM10




RNA binding motif protein 10




chr3_-_121553907 5.784 NM_001023570
NM_001023571
IQCB1

IQ motif containing B1

chrX_+_47004670 5.782 RBM10
RNA binding motif protein 10
chr4_-_84035888 5.768 PLAC8
placenta-specific 8
chr1_+_110881944 5.696 NM_001201545
NM_022768
RBM15

RNA binding motif protein 15

chr9_+_36190885 5.689 CLTA
clathrin, light chain A
chr2_-_61765367 5.675 XPO1
exportin 1 (CRM1 homolog, yeast)
chr19_-_39881503 5.667 PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr17_-_1588098 5.635 PRPF8
PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)
chr17_-_79818318 5.618 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr22_-_30642683 5.611 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr2_-_61765345 5.610 XPO1
exportin 1 (CRM1 homolog, yeast)
chr3_-_121553836 5.596 IQCB1
IQ motif containing B1
chr22_-_17640153 5.592 CECR5
cat eye syndrome chromosome region, candidate 5
chr19_+_54704659 5.506 NM_001013
RPS9
ribosomal protein S9
chr12_-_54653317 5.501 NM_001127322
CBX5
chromobox homolog 5
chr3_-_160283311 5.475 KPNA4
karyopherin alpha 4 (importin alpha 3)
chr18_-_47018842 5.424 NM_001199356
NM_000985
NM_001035006
NM_001199340
NM_001199345
RPL17-C18ORF32
RPL17



RPL17-C18orf32 readthrough
ribosomal protein L17



chr10_+_70660955 5.382 NM_024045
DDX50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr14_+_93673583 5.353 UBR7
ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr14_+_96001297 5.326 NM_016417
GLRX5
glutaredoxin 5
chr20_+_18488525 5.306 SEC23B
Sec23 homolog B (S. cerevisiae)
chrX_+_70503534 5.260 NONO
non-POU domain containing, octamer-binding

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.15 2.50e-12 GO:0034621 cellular macromolecular complex subunit organization
4.76 3.54e-12 GO:0034622 cellular macromolecular complex assembly
2.36 3.71e-10 GO:0006996 organelle organization
1.99 3.83e-10 GO:0071842 cellular component organization at cellular level
8.17 4.51e-10 GO:0065004 protein-DNA complex assembly
1.96 6.74e-10 GO:0071841 cellular component organization or biogenesis at cellular level
7.73 1.33e-09 GO:0071824 protein-DNA complex subunit organization
1.78 4.00e-09 GO:0071840 cellular component organization or biogenesis
1.78 1.03e-08 GO:0016043 cellular component organization
6.42 4.77e-08 GO:0006333 chromatin assembly or disassembly
2.75 2.31e-07 GO:0043933 macromolecular complex subunit organization
3.11 2.49e-07 GO:0051276 chromosome organization
7.53 3.91e-07 GO:0006334 nucleosome assembly
2.82 6.34e-07 GO:0071844 cellular component assembly at cellular level
7.14 8.85e-07 GO:0031497 chromatin assembly
2.87 9.59e-07 GO:0065003 macromolecular complex assembly
6.79 1.91e-06 GO:0034728 nucleosome organization
2.79 5.62e-06 GO:0022403 cell cycle phase
5.80 7.13e-06 GO:0006323 DNA packaging
3.62 1.07e-05 GO:0010564 regulation of cell cycle process
2.20 1.17e-05 GO:0051641 cellular localization
5.27 1.19e-05 GO:0071103 DNA conformation change
2.24 1.69e-05 GO:0044085 cellular component biogenesis
1.21 1.72e-05 GO:0009987 cellular process
3.26 1.80e-05 GO:0000279 M phase
2.88 2.48e-05 GO:0000278 mitotic cell cycle
4.29 2.80e-05 GO:0071156 regulation of cell cycle arrest
2.49 6.08e-05 GO:0022402 cell cycle process
4.25 7.26e-05 GO:0000075 cell cycle checkpoint
2.21 9.72e-05 GO:0051649 establishment of localization in cell
4.75 1.45e-04 GO:0043623 cellular protein complex assembly
2.19 3.15e-04 GO:0022607 cellular component assembly
7.22 3.90e-04 GO:0010948 negative regulation of cell cycle process
2.16 4.99e-04 GO:0008104 protein localization
2.17 7.99e-04 GO:0007049 cell cycle
1.45 1.02e-03 GO:0044260 cellular macromolecule metabolic process
2.26 1.15e-03 GO:0045184 establishment of protein localization
2.25 1.88e-03 GO:0015031 protein transport
3.33 1.99e-03 GO:0000280 nuclear division
3.33 1.99e-03 GO:0007067 mitosis
3.43 2.33e-03 GO:0007346 regulation of mitotic cell cycle
1.94 2.98e-03 GO:0033036 macromolecule localization
3.24 3.16e-03 GO:0000087 M phase of mitotic cell cycle
3.24 3.16e-03 GO:0051329 interphase of mitotic cell cycle
2.73 3.26e-03 GO:0006325 chromatin organization
3.23 3.35e-03 GO:0048285 organelle fission
2.45 3.92e-03 GO:0051726 regulation of cell cycle
3.18 4.18e-03 GO:0051325 interphase
2.25 4.47e-03 GO:0046907 intracellular transport
1.32 6.99e-03 GO:0044237 cellular metabolic process
2.92 1.00e-02 GO:0051301 cell division
9.19 1.13e-02 GO:0034976 response to endoplasmic reticulum stress
3.39 1.58e-02 GO:0051129 negative regulation of cellular component organization
2.75 1.58e-02 GO:0006886 intracellular protein transport
2.50 1.68e-02 GO:0034613 cellular protein localization
2.48 1.88e-02 GO:0070727 cellular macromolecule localization
4.17 1.95e-02 GO:0006310 DNA recombination
1.35 2.55e-02 GO:0043170 macromolecule metabolic process
4.33 2.85e-02 GO:0010639 negative regulation of organelle organization
2.87 3.28e-02 GO:0033043 regulation of organelle organization
1.60 3.47e-02 GO:0090304 nucleic acid metabolic process
4.19 3.96e-02 GO:0007093 mitotic cell cycle checkpoint
6.42 4.13e-02 GO:0045732 positive regulation of protein catabolic process
7.58 4.29e-02 GO:0030071 regulation of mitotic metaphase/anaphase transition

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.39 3.48e-17 GO:0043229 intracellular organelle
1.39 4.86e-17 GO:0043226 organelle
1.30 1.94e-16 GO:0044424 intracellular part
1.42 2.52e-15 GO:0043231 intracellular membrane-bounded organelle
1.42 3.02e-15 GO:0043227 membrane-bounded organelle
1.28 5.77e-15 GO:0005622 intracellular
1.64 2.99e-14 GO:0044446 intracellular organelle part
1.63 6.64e-14 GO:0044422 organelle part
1.86 4.50e-09 GO:0043228 non-membrane-bounded organelle
1.86 4.50e-09 GO:0043232 intracellular non-membrane-bounded organelle
1.35 5.04e-09 GO:0005737 cytoplasm
3.31 7.07e-09 GO:0005694 chromosome
3.55 9.98e-09 GO:0044427 chromosomal part
1.96 1.15e-08 GO:0070013 intracellular organelle lumen
1.49 2.88e-08 GO:0005634 nucleus
1.92 3.44e-08 GO:0043233 organelle lumen
1.68 5.94e-08 GO:0032991 macromolecular complex
1.89 8.34e-08 GO:0031974 membrane-enclosed lumen
1.89 5.32e-07 GO:0044428 nuclear part
4.33 9.30e-07 GO:0000785 chromatin
6.84 1.09e-06 GO:0032993 protein-DNA complex
8.66 2.48e-06 GO:0000786 nucleosome
1.89 1.04e-05 GO:0031981 nuclear lumen
1.37 3.56e-05 GO:0044444 cytoplasmic part
1.98 1.56e-04 GO:0005654 nucleoplasm
1.64 2.66e-03 GO:0005829 cytosol
1.07 3.59e-03 GO:0044464 cell part
1.07 3.64e-03 GO:0005623 cell
3.63 4.46e-03 GO:0005819 spindle
5.91 4.98e-03 GO:0000922 spindle pole
2.95 6.80e-03 GO:0005874 microtubule
7.77 6.88e-03 GO:0005876 spindle microtubule
12.03 1.10e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
2.30 1.78e-02 GO:0030529 ribonucleoprotein complex
1.45 2.08e-02 GO:0043234 protein complex
1.83 2.23e-02 GO:0005783 endoplasmic reticulum
3.10 2.82e-02 GO:0000228 nuclear chromosome
2.05 4.30e-02 GO:0015630 microtubule cytoskeleton

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.34 2.97e-06 GO:0005515 protein binding
8.36 1.65e-05 GO:0003697 single-stranded DNA binding
1.15 1.08e-03 GO:0005488 binding
2.06 6.78e-03 GO:0003723 RNA binding
3.51 7.06e-03 GO:0043566 structure-specific DNA binding
1.44 9.33e-03 GO:0003676 nucleic acid binding