Motif ID: POU1F1.p2

Z-value: 2.426


Transcription factors associated with POU1F1.p2:

Gene SymbolEntrez IDGene Name
POU1F1 5449 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU1F1chr3_-_873256110.656.4e-28Click!


Activity profile for motif POU1F1.p2.

activity profile for motif POU1F1.p2


Sorted Z-values histogram for motif POU1F1.p2

Sorted Z-values for motif POU1F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU1F1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_93399531 49.766


chr12_-_91573264 45.112 NM_133503
DCN
decorin
chr6_-_52628272 34.139 NM_000846
GSTA2
glutathione S-transferase alpha 2
chr12_-_45307710 31.768 NM_001145110
NELL2
NEL-like 2 (chicken)
chr4_+_74270832 30.682 ALB
albumin
chr14_-_107013474 29.248 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_+_196857143 27.912 NM_001201550
NM_001201551
NM_006684
CFHR4


complement factor H-related 4


chr4_+_106631966 27.707 NM_001031720
GSTCD
glutathione S-transferase, C-terminal domain containing
chr6_-_33041266 27.577 NM_033554
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr7_-_64023444 27.345


chr1_+_196743929 25.784 NM_001166624
NM_021023
CFHR3

complement factor H-related 3

chr5_-_41213513 25.269 NM_000065
C6
complement component 6
chr12_+_21679190 25.163 NM_030572
C12orf39
chromosome 12 open reading frame 39
chr1_-_163172863 24.723 NM_003617
RGS5
regulator of G-protein signaling 5
chr1_-_161279724 23.629 NM_000530
MPZ
myelin protein zero
chr8_-_86253863 23.282 NM_001164830
CA1
carbonic anhydrase I
chr12_-_87232635 22.954 NM_013244
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr4_+_71337833 22.892 NM_152291
MUC7
mucin 7, secreted
chr4_+_71337674 22.428 NM_001145007
MUC7
mucin 7, secreted
chr16_-_5116030 22.050 NM_001098514
NM_152459
C16orf89

chromosome 16 open reading frame 89

chr5_+_40909617 21.966 C7
complement component 7
chr5_+_40909558 21.616 NM_000587
C7
complement component 7
chr6_+_72922513 21.526 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr10_+_104613966 21.297 NM_001136200
NM_144591
C10orf32-AS3MT
C10orf32

C10orf32-AS3MT readthrough
chromosome 10 open reading frame 32

chr20_+_30102261 21.042 HM13
histocompatibility (minor) 13
chr3_-_121379757 20.854 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr4_-_100242487 20.355 NM_000668
ADH1A
ADH1B
alcohol dehydrogenase 1A (class I), alpha polypeptide
alcohol dehydrogenase 1B (class I), beta polypeptide
chr3_-_121379701 19.631 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr14_-_106610338 19.607 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr5_-_75919051 19.555 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr4_+_71263598 19.337 NM_021225
PROL1
proline rich, lacrimal 1
chr2_-_26700909 19.247 NM_004802
NM_194322
NM_194323
OTOF


otoferlin


chr6_+_153019029 18.916 NM_025107
MYCT1
myc target 1
chr18_-_40695483 18.890 NM_002930
RIT2
Ras-like without CAAX 2
chr12_-_91576579 18.756 DCN
decorin
chr3_+_122296432 18.673 NM_001113523
PARP15
poly (ADP-ribose) polymerase family, member 15
chr10_+_101088794 18.268 NM_020348
CNNM1
cyclin M1
chrX_+_7810302 18.200 NM_013452
VCX
variable charge, X-linked
chr6_-_22297729 18.015 NM_000948
PRL
prolactin
chr5_+_54320083 17.988 NM_002104
GZMK
granzyme K (granzyme 3; tryptase II)
chr11_-_114466397 17.926 FAM55D
family with sequence similarity 55, member D
chr9_-_21368005 17.263 NM_006900
IFNA1
IFNA13
interferon, alpha 1
interferon, alpha 13
chr1_+_196788860 17.239 NM_002113
CFHR1
complement factor H-related 1
chr15_-_45670624 16.775 GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr17_-_29641068 16.589 EVI2B
ecotropic viral integration site 2B
chr3_+_38347426 16.541 NM_004803
SLC22A14
solute carrier family 22, member 14
chr4_-_71532341 16.124 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr19_+_42381189 15.922 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr6_+_32407618 15.876 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chrY_-_6742028 15.875 NM_001143
AMELY
amelogenin, Y-linked
chr22_+_24033047 15.841 NM_153615
RGL4
ral guanine nucleotide dissociation stimulator-like 4
chr14_-_106774311 15.511 IGHA1
immunoglobulin heavy constant alpha 1
chr1_+_196912910 15.421 NM_005666
CFHR2
complement factor H-related 2
chr16_-_21314371 15.400 NM_001014444
NM_001888
CRYM

crystallin, mu

chr4_+_74269971 15.379 NM_000477
ALB
albumin
chr6_+_28109611 15.351 NM_006298
ZNF192
zinc finger protein 192
chr4_-_100273831 15.299 NM_000669
ADH1C
alcohol dehydrogenase 1C (class I), gamma polypeptide
chr18_-_64271215 15.231 NM_021153
CDH19
cadherin 19, type 2
chr6_-_32634287 15.110 NM_001243961
NM_002123
HLA-DQB1

major histocompatibility complex, class II, DQ beta 1

chr1_-_57045214 14.991 PPAP2B
phosphatidic acid phosphatase type 2B
chr2_+_79347487 14.935 NM_002909
REG1A
regenerating islet-derived 1 alpha
chr9_-_21187529 14.914 NM_021068
IFNA4
interferon, alpha 4
chr11_-_114466471 14.597 NM_001077639
NM_017678
FAM55D

family with sequence similarity 55, member D

chr21_-_31538970 14.582 NM_012131
CLDN17
claudin 17
chr3_+_108021331 14.518 NM_007072
HHLA2
HERV-H LTR-associating 2
chr5_-_58295758 14.369 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_+_172389827 14.068 NM_139240
C1orf105
chromosome 1 open reading frame 105
chrX_-_2882288 13.921 NM_000047
ARSE
arylsulfatase E (chondrodysplasia punctata 1)
chr1_+_147374945 13.882 NM_005267
GJA8
gap junction protein, alpha 8, 50kDa
chr8_-_82395401 13.825 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr1_+_153003677 13.595 NM_003125
SPRR1B
small proline-rich protein 1B
chr17_-_34313685 13.440 NM_032962
NM_032963
CCL14

chemokine (C-C motif) ligand 14

chrY_+_20297334 13.310 NM_001002906
NM_004677
XKRY2
XKRY
XK, Kell blood group complex subunit-related, Y-linked 2
XK, Kell blood group complex subunit-related, Y-linked
chr6_+_131958441 13.086 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr12_+_7167979 13.047 NM_001734
NM_201442
C1S

complement component 1, s subcomponent

chr14_-_101036130 13.018 NM_020836
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chr1_-_35497563 13.008 NM_007167
ZMYM6
zinc finger, MYM-type 6
chr12_+_57157091 12.979 NM_003725
HSD17B6
hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse)
chr4_-_71532206 12.857 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr16_-_3627353 12.811 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr14_-_64749530 12.791 NM_001214902
NM_001214903
ESR2

estrogen receptor 2 (ER beta)

chr3_-_195310985 12.762 NM_001647
APOD
apolipoprotein D
chr9_+_21440452 12.598 NM_024013
IFNA1
interferon, alpha 1
chr19_+_39971051 12.570 NM_001001563
TIMM50
translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
chr4_+_88720701 12.479 NM_004967
IBSP
integrin-binding sialoprotein
chr7_+_102023016 12.461


chr19_-_21646685 12.360


chr2_-_77749335 12.127 NM_001134745
NM_024993
LRRTM4

leucine rich repeat transmembrane neuronal 4

chr9_-_23821842 12.121 NM_001171195
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr4_+_88742549 12.110 NM_001184694
MEPE
matrix extracellular phosphoglycoprotein
chr6_-_52668599 12.087 NM_145740
GSTA1
glutathione S-transferase alpha 1
chr11_+_124824076 12.034 CCDC15
coiled-coil domain containing 15
chrX_+_66788682 11.827 NM_001011645
AR
androgen receptor
chr9_-_70429730 11.731 NM_001099279
NM_199244
FOXD4L2
FOXD4L4
forkhead box D4-like 2
forkhead box D4-like 4
chr5_-_39203061 11.614 FYB
FYN binding protein
chr9_-_21350885 11.594 NM_021002
IFNA6
interferon, alpha 6
chr20_+_30102237 11.573 NM_030789
NM_178580
NM_178581
NM_178582
HM13



histocompatibility (minor) 13



chr1_+_160336856 11.363 NM_005598
NHLH1
nescient helix loop helix 1
chr4_-_100212085 11.150 NM_000667
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr9_-_123812535 11.062 NM_001735
C5
complement component 5
chr19_+_840970 11.048 NM_002777
PRTN3
proteinase 3
chr11_-_36619776 10.995 NM_000536
NM_001243785
NM_001243786
RAG2


recombination activating gene 2


chr1_+_207277577 10.860 NM_000715
C4BPA
complement component 4 binding protein, alpha
chrY_-_19882311 10.764 NM_001002906
NM_004677
XKRY2
XKRY
XK, Kell blood group complex subunit-related, Y-linked 2
XK, Kell blood group complex subunit-related, Y-linked
chr6_+_72926462 10.663 NM_001168410
RIMS1
regulating synaptic membrane exocytosis 1
chr16_+_67381252 10.601 NM_001161575
LRRC36
leucine rich repeat containing 36
chr13_+_111855406 10.598 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr9_+_102677457 10.579 STX17
syntaxin 17
chr3_+_148447966 10.571 NM_032049
AGTR1
angiotensin II receptor, type 1
chr4_+_69681709 10.565 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr17_+_33448597 10.466 NM_017559
FNDC8
fibronectin type III domain containing 8
chr6_-_32920812 10.460 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chrX_-_138724851 10.344 NM_001171877
NM_001171878
NM_001171879
NM_005369
MCF2



MCF.2 cell line derived transforming sequence



chr6_-_49844808 10.289 NM_001205220
CRISP1
cysteine-rich secretory protein 1
chr1_-_217113007 10.242 NM_001243512
NM_001243513
NM_001243510
NM_001243511
ESRRG



estrogen-related receptor gamma



chr4_+_71226477 10.205 NM_012390
SMR3B
SMR3A
submaxillary gland androgen regulated protein 3B
submaxillary gland androgen regulated protein 3A
chr9_-_23821808 10.117 ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr7_+_37723378 9.916


chr9_+_42717233 9.884 NM_001099279
NM_199244
FOXD4L2
FOXD4L4
forkhead box D4-like 2
forkhead box D4-like 4
chr2_+_79347610 9.880 REG1A
regenerating islet-derived 1 alpha
chr7_-_14880954 9.690 NM_004080
NM_145695
DGKB

diacylglycerol kinase, beta 90kDa

chr12_-_52886971 9.686 NM_005554
KRT6A
keratin 6A
chr10_+_32856650 9.578 NM_024688
C10orf68
chromosome 10 open reading frame 68
chr2_-_174767282 9.564


chr3_+_101546833 9.534 NM_001005474
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr12_-_371994 9.469 NM_001190997
NM_001243392
NM_016615
SLC6A13


solute carrier family 6 (neurotransmitter transporter, GABA), member 13


chr4_-_87028805 9.447 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr16_-_23724820 9.444 NM_033266
ERN2
endoplasmic reticulum to nucleus signaling 2
chr1_+_171154387 9.341 NM_001460
FMO2
flavin containing monooxygenase 2 (non-functional)
chr8_-_42623928 9.231 NM_001199279
NM_004198
CHRNA6

cholinergic receptor, nicotinic, alpha 6

chr12_-_10282680 9.145 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
CLEC7A





C-type lectin domain family 7, member A





chr9_-_70178814 9.124 NM_001126334
FOXD4L5
forkhead box D4-like 5
chr1_+_92632608 9.109 NM_015237
KIAA1107
KIAA1107
chr11_-_128457452 9.102 NM_001143820
ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr7_+_123565908 8.928 NM_001174045
NM_001174046
SPAM1

sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)

chr9_-_21142143 8.764 NM_002177
IFNW1
interferon, omega 1
chr14_-_106405633 8.760 IGHM
immunoglobulin heavy constant mu
chr8_+_24151579 8.749 NM_014265
NM_021777
ADAM28

ADAM metallopeptidase domain 28

chr4_-_47983430 8.722 NM_001142564
CNGA1
cyclic nucleotide gated channel alpha 1
chr1_+_152881022 8.704 NM_005547
IVL
involucrin
chr4_+_187148624 8.662 NM_000892
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr12_-_10151689 8.653 NM_001099431
NM_016509
CLEC1B

C-type lectin domain family 1, member B

chr3_-_194072004 8.594 NM_001080513
CPN2
carboxypeptidase N, polypeptide 2
chr13_-_46756295 8.592 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_114522029 8.547 NM_020190
OLFML3
olfactomedin-like 3
chr13_+_49684388 8.517 NM_014923
FNDC3A
fibronectin type III domain containing 3A
chr12_-_30830143 8.444 NM_001190995
IPO8
importin 8
chr11_-_85376159 8.427 NM_001039618
CREBZF
CREB/ATF bZIP transcription factor
chr8_-_17752847 8.405 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr10_+_96443250 8.334 NM_000772
NM_001128925
CYP2C18

cytochrome P450, family 2, subfamily C, polypeptide 18

chr17_-_3301703 8.315 NM_003553
OR1E1
olfactory receptor, family 1, subfamily E, member 1
chr1_-_20445991 8.289 NM_012400
PLA2G2D
phospholipase A2, group IID
chr4_-_39033981 8.282 NM_024943
TMEM156
transmembrane protein 156
chr3_+_46619075 8.137 NM_003212
TDGF1
teratocarcinoma-derived growth factor 1
chr4_+_70894129 8.133 NM_000200
HTN3
histatin 3
chr5_-_149792276 8.128 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr4_-_70505359 8.083 NM_001105677
UGT2A2
UDP glucuronosyltransferase 2 family, polypeptide A2
chr6_-_32557431 8.082 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr4_-_76944585 8.023 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr9_+_100263461 8.013 NM_001166116
TMOD1
tropomodulin 1
chr14_-_106641585 7.967 IGHV4-31
IGHA1
IGHA2
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
chr9_-_5304579 7.938 NM_005059
NM_134441
RLN2

relaxin 2

chrX_+_119384490 7.900 NM_006777
NM_001184742
ZBTB33

zinc finger and BTB domain containing 33

chr9_+_71944240 7.899 NM_004816
FAM189A2
family with sequence similarity 189, member A2
chr4_+_74281884 7.882 ALB
albumin
chr1_-_13390747 7.866 NM_001012276
PRAMEF8
PRAMEF7
PRAME family member 8
PRAME family member 7
chrX_-_19988381 7.838 NM_198279
CXorf23
chromosome X open reading frame 23
chr5_+_156696351 7.837 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr2_+_68592317 7.830 NM_002664
PLEK
pleckstrin
chr1_-_57045235 7.829 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr20_-_45061554 7.822 ELMO2
engulfment and cell motility 2
chr5_+_140220811 7.822 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr7_+_137761177 7.811 NM_001190906
NM_001190907
NM_005989
AKR1D1


aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)


chr5_-_997408 7.798 NM_001242737
LOC100506688
uncharacterized LOC100506688
chr17_+_74463629 7.781 NM_001088
AANAT
aralkylamine N-acetyltransferase
chr19_-_48389514 7.700 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr11_-_102401430 7.664 NM_002423
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr7_+_29519485 7.636 NM_001039936
CHN2
chimerin (chimaerin) 2
chr8_-_87755880 7.604 NM_019098
CNGB3
cyclic nucleotide gated channel beta 3
chr4_+_71108304 7.579 NM_005212
CSN3
casein kappa
chr19_+_48949241 7.578 GRWD1
glutamate-rich WD repeat containing 1
chr19_+_840963 7.548 PRTN3
proteinase 3
chr12_+_56324945 7.492 NM_001345
DGKA
diacylglycerol kinase, alpha 80kDa
chr3_+_151488214 7.491 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr4_+_113739203 7.490 NM_001127493
ANK2
ankyrin 2, neuronal
chr4_-_100356449 7.486 NM_000673
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr4_-_16077740 7.481 NM_001145849
NM_001145850
NM_001145851
NM_001145852
NM_006017
PROM1




prominin 1




chr6_-_149806116 7.451 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr21_-_15918635 7.428 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr2_+_68592432 7.381 PLEK
pleckstrin
chr2_+_169921298 7.350 NM_005771
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr6_+_26087447 7.348 NM_000410
NM_139003
NM_139004
NM_139006
NM_139007
NM_139008
NM_139009
NM_139010
NM_139011
HFE








hemochromatosis








chr7_+_143412938 7.223 NM_001130026
FAM115C
family with sequence similarity 115, member C
chr4_+_175839508 7.193 NM_001130703
NM_001130704
NM_001130705
NM_014269
ADAM29



ADAM metallopeptidase domain 29



chr12_-_21487831 7.186 NM_021094
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr5_-_115152322 7.142 NM_001801
CDO1
cysteine dioxygenase, type I
chr6_-_90024936 7.119 NM_002043
GABRR2
gamma-aminobutyric acid (GABA) receptor, rho 2
chr4_-_70080448 7.089 NM_001073
UGT2B11
UGT2B10
UDP glucuronosyltransferase 2 family, polypeptide B11
UDP glucuronosyltransferase 2 family, polypeptide B10
chrX_-_49965657 7.073 NM_003886
AKAP4
A kinase (PRKA) anchor protein 4
chr16_-_21663908 7.072 IGSF6
immunoglobulin superfamily, member 6

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.16 5.47e-16 GO:0006955 immune response
2.35 1.67e-11 GO:0002376 immune system process
2.72 2.43e-11 GO:0006952 defense response
3.42 6.40e-11 GO:0050776 regulation of immune response
1.38 1.08e-07 GO:0050896 response to stimulus
2.50 4.73e-07 GO:0002682 regulation of immune system process
2.93 1.85e-05 GO:0045087 innate immune response
3.18 3.32e-05 GO:0050778 positive regulation of immune response
1.73 3.76e-05 GO:0048583 regulation of response to stimulus
3.51 4.00e-05 GO:0002253 activation of immune response
4.32 5.06e-05 GO:0006805 xenobiotic metabolic process
4.32 5.06e-05 GO:0071466 cellular response to xenobiotic stimulus
13.52 5.71e-05 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
4.29 5.76e-05 GO:0009410 response to xenobiotic stimulus
3.41 7.09e-05 GO:0008202 steroid metabolic process
2.54 4.60e-04 GO:0002684 positive regulation of immune system process
6.27 4.72e-04 GO:0019882 antigen processing and presentation
3.44 6.79e-04 GO:0019221 cytokine-mediated signaling pathway
8.62 7.90e-04 GO:0060338 regulation of type I interferon-mediated signaling pathway
3.24 1.07e-03 GO:0071345 cellular response to cytokine stimulus
5.65 1.55e-03 GO:0072376 protein activation cascade
5.05 2.14e-03 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
4.91 2.94e-03 GO:0002250 adaptive immune response
2.74 3.26e-03 GO:0034097 response to cytokine stimulus
5.75 3.69e-03 GO:0016064 immunoglobulin mediated immune response
5.64 4.45e-03 GO:0019724 B cell mediated immunity
4.10 5.11e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
6.99 5.53e-03 GO:0008206 bile acid metabolic process
5.00 6.09e-03 GO:0002449 lymphocyte mediated immunity
1.34 1.04e-02 GO:0051716 cellular response to stimulus
1.87 1.21e-02 GO:0009611 response to wounding
3.98 1.55e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
10.77 1.56e-02 GO:0015721 bile acid and bile salt transport
6.16 1.70e-02 GO:0006956 complement activation
4.31 2.94e-02 GO:0006959 humoral immune response
6.57 3.18e-02 GO:0002455 humoral immune response mediated by circulating immunoglobulin
1.37 3.19e-02 GO:0007165 signal transduction
1.80 3.53e-02 GO:0070887 cellular response to chemical stimulus
11.97 4.94e-02 GO:0010885 regulation of cholesterol storage

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.97 1.38e-12 GO:0005576 extracellular region
2.62 5.55e-11 GO:0005615 extracellular space
2.32 5.48e-10 GO:0044421 extracellular region part
2.16 1.16e-09 GO:0005887 integral to plasma membrane
2.14 1.27e-09 GO:0031226 intrinsic to plasma membrane
1.78 9.25e-09 GO:0044459 plasma membrane part
16.41 1.21e-06 GO:0042613 MHC class II protein complex
1.41 9.07e-06 GO:0071944 cell periphery
8.98 1.83e-05 GO:0042611 MHC protein complex
1.40 2.29e-05 GO:0005886 plasma membrane
1.82 7.28e-03 GO:0005626 insoluble fraction
1.77 2.58e-02 GO:0005624 membrane fraction

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.83 6.65e-06 GO:0005126 cytokine receptor binding
21.54 1.87e-05 GO:0005132 interferon-alpha/beta receptor binding
3.26 4.56e-04 GO:0005125 cytokine activity
15.96 2.32e-03 GO:0004022 alcohol dehydrogenase (NAD) activity
1.59 3.67e-03 GO:0004872 receptor activity
1.49 9.95e-03 GO:0004871 signal transducer activity
1.49 9.95e-03 GO:0060089 molecular transducer activity
7.18 1.53e-02 GO:0016229 steroid dehydrogenase activity
11.05 2.11e-02 GO:0004993 serotonin receptor activity
5.75 2.41e-02 GO:0003823 antigen binding
1.60 3.72e-02 GO:0004888 transmembrane receptor activity
14.36 3.75e-02 GO:0032395 MHC class II receptor activity