Motif ID: POU5F1.p2

Z-value: 3.451


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_311381800.351.3e-07Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_176734181 68.085 NM_201591
GPM6A
glycoprotein M6A
chr12_-_16757944 65.734 LMO3
LIM domain only 3 (rhombotin-like 2)
chr14_-_106733392 62.463 IGHG1
IGHG3
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr7_-_37024664 62.187 NM_001039459
ELMO1
engulfment and cell motility 1
chrX_-_13835012 56.758 GPM6B
glycoprotein M6B
chr2_-_89442551 53.849 IGKC
IGK@
immunoglobulin kappa constant
immunoglobulin kappa locus
chr18_-_53089722 53.831 NM_001243233
TCF4
transcription factor 4
chr22_+_23213671 52.406 IGLV4-3
immunoglobulin lambda variable 4-3
chr22_+_22697538 52.237


chr22_+_22735134 50.472 CYAT1
immunoglobulin lambda light chain-like
chrX_-_13835313 48.484 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr22_+_22758538 48.224


chr6_-_108145507 46.920 NM_198081
SCML4
sex comb on midleg-like 4 (Drosophila)
chr2_+_89185055 46.123


chrX_-_13835213 44.354 GPM6B
glycoprotein M6B
chrX_-_13835187 43.308 GPM6B
glycoprotein M6B
chr16_+_23847321 42.987 PRKCB
protein kinase C, beta
chr14_-_107066061 42.672 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_-_106960268 41.169 NM_004089
TSC22D3
TSC22 domain family, member 3
chr14_-_107179043 40.936 IGHA1
immunoglobulin heavy constant alpha 1
chr22_+_22735207 40.483 IGLJ3
immunoglobulin lambda joining 3
chr12_-_91576579 39.857 DCN
decorin
chr18_-_52988916 39.147 NM_001243234
NM_001243235
TCF4

transcription factor 4

chr12_-_16758312 38.372 NM_001243611
LMO3
LIM domain only 3 (rhombotin-like 2)
chrX_-_106960028 38.271 TSC22D3
TSC22 domain family, member 3
chr22_+_23040394 37.618 IGL@
immunoglobulin lambda locus
chr12_-_16760935 36.968 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr17_+_7554415 36.937 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr16_+_23847271 36.442 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr22_+_22712091 36.390 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr14_-_107013474 36.121 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr16_+_23847359 35.949 PRKCB
protein kinase C, beta
chr22_+_23010757 35.941


chr17_+_7554239 35.513 NM_001678
ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr22_+_23165273 35.343


chr10_+_11207053 34.985 CELF2
CUGBP, Elav-like family member 2
chr22_+_22786283 34.972


chr22_+_23063107 34.928 IGLJ3
immunoglobulin lambda joining 3
chr16_-_4322695 34.069 TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr4_-_176733901 33.915 GPM6A
glycoprotein M6A
chr7_-_130080823 33.749 NM_018718
CEP41
centrosomal protein 41kDa
chr4_-_153303663 33.453 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr1_-_153363544 33.446 NM_002964
S100A8
S100 calcium binding protein A8
chr4_-_176733413 33.349 GPM6A
glycoprotein M6A
chr1_+_228645807 32.110 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chr1_-_31230673 31.391 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr14_-_107131217 31.363 IGHA1
immunoglobulin heavy constant alpha 1
chr12_-_16759733 31.122 NM_001243610
LMO3
LIM domain only 3 (rhombotin-like 2)
chr2_-_175712276 30.929 NM_001206602
CHN1
chimerin (chimaerin) 1
chr2_+_90077732 30.625


chr16_-_4323000 30.466 NM_003223
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr14_-_106405633 30.029 IGHM
immunoglobulin heavy constant mu
chr4_+_158141735 29.904 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr19_-_18314731 28.843 NM_002866
RAB3A
RAB3A, member RAS oncogene family
chr19_-_39108534 28.636 NM_001042600
NM_007181
MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1

chr22_+_22676814 28.561


chr14_-_107170400 28.463 IGHV4-31
IGHV1-69
IGHA1
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 1-69
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr17_-_8063946 28.427 VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr12_-_16759939 27.933 NM_001243613
LMO3
LIM domain only 3 (rhombotin-like 2)
chr2_+_68961912 27.873 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr3_-_18480203 26.649 NM_001131010
SATB1
SATB homeobox 1
chr22_+_23134980 26.534


chr2_-_89513056 25.802 IGKC
immunoglobulin kappa constant
chr14_-_106641585 25.358 IGHV4-31
IGHA1
IGHA2
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
chr9_+_137967088 25.335 NM_014279
NM_006334
OLFM1

olfactomedin 1

chr14_-_106967528 25.303 IGHA1
IGHA2
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr12_-_91576805 25.287 NM_001920
DCN
decorin
chr17_+_7554711 24.956 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr12_-_16759430 24.874 LMO3
LIM domain only 3 (rhombotin-like 2)
chr17_+_20771745 24.850


chr14_-_21271002 24.722 NM_002933
NM_198234
NM_198235
RNASE1


ribonuclease, RNase A family, 1 (pancreatic)


chr19_-_44123732 24.713 ZNF428
zinc finger protein 428
chr20_+_17207680 24.618 PCSK2
proprotein convertase subtilisin/kexin type 2
chr22_+_22735202 24.470


chr7_-_31380507 23.967 NM_022728
NEUROD6
neurogenic differentiation 6
chr8_-_27115897 23.902 NM_030795
STMN4
stathmin-like 4
chr10_+_11206928 23.807 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr20_+_17207669 23.668 PCSK2
proprotein convertase subtilisin/kexin type 2
chr12_-_16759531 23.527 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr22_+_23154240 22.845


chr4_-_71532206 22.823 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr15_+_91769329 22.758 SV2B
synaptic vesicle glycoprotein 2B
chr18_-_53255361 22.452 TCF4
transcription factor 4
chr2_+_90211704 22.359


chr17_-_38256548 22.300 NR1D1
nuclear receptor subfamily 1, group D, member 1
chr9_+_137967401 22.267 OLFM1
olfactomedin 1
chr17_+_38219040 22.222 NM_001190918
NM_003250
NM_199334
THRA


thyroid hormone receptor, alpha


chr11_-_62369097 21.924 MTA2
metastasis associated 1 family, member 2
chr18_-_53255734 21.812 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr1_+_84609941 21.784 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr14_-_106746056 21.721


chr2_+_17721806 21.537 NM_003385
VSNL1
visinin-like 1
chr4_-_71532341 21.529 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr13_-_30881141 21.486 NM_001014380
KATNAL1
katanin p60 subunit A-like 1
chr18_-_53257033 21.471 NM_001243227
NM_001243228
TCF4

transcription factor 4

chr1_-_228645517 21.377 NM_033445
HIST3H2A
histone cluster 3, H2a
chr5_-_88179278 21.248 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr2_+_17721983 20.881 VSNL1
visinin-like 1
chr22_+_23029175 20.690 IGLV3-25
immunoglobulin lambda variable 3-25
chr14_-_106494166 20.499 IGHV4-31
IGHA1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
chr2_-_89619820 20.467 IGKC
immunoglobulin kappa constant
chr6_-_32908583 20.422 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr14_-_106610338 20.167 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_+_22550112 20.148


chr1_-_177133950 20.127 NM_004319
NM_207108
ASTN1

astrotactin 1

chr1_-_149858114 19.869 NM_003528
HIST2H2BE
histone cluster 2, H2be
chr14_-_106691698 19.828


chr1_+_155853546 19.605 SYT11
synaptotagmin XI
chr7_-_100183722 19.435 LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr6_-_154651214 19.326 NM_001130699
IPCEF1
interaction protein for cytohesin exchange factors 1
chr15_+_84115979 19.150 NM_003027
SH3GL3
SH3-domain GRB2-like 3
chr1_+_50574601 19.127 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr12_-_51611476 18.972 POU6F1
POU class 6 homeobox 1
chr17_-_62009620 18.841 NM_000626
NM_001039933
NM_021602
CD79B


CD79b molecule, immunoglobulin-associated beta


chr8_+_26435339 18.718 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chr9_+_137967366 18.675 OLFM1
olfactomedin 1
chr9_-_35732089 18.583 TLN1
talin 1
chr12_+_14518608 18.573 NM_018179
ATF7IP
activating transcription factor 7 interacting protein
chr3_+_181430075 18.549 SOX2
SRY (sex determining region Y)-box 2
chr12_-_45269340 18.064 NM_001145109
NELL2
NEL-like 2 (chicken)
chr11_-_62369213 18.011 MTA2
metastasis associated 1 family, member 2
chr7_-_126883568 18.004 NM_000845
GRM8
glutamate receptor, metabotropic 8
chr17_-_8815799 17.933 NM_014308
PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr2_+_220378891 17.902 NM_018674
NM_182847
ACCN4

amiloride-sensitive cation channel 4, pituitary

chr19_-_1021122 17.882 NM_001033026
NM_033420
C19orf6

chromosome 19 open reading frame 6

chr4_-_153273683 17.844 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr9_-_34691135 17.787 NM_006274
CCL19
chemokine (C-C motif) ligand 19
chr6_-_35656610 17.674 FKBP5
FK506 binding protein 5
chr5_+_36608430 17.350 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_-_167005641 17.254 NM_001202435
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr16_-_79634610 17.239 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr14_-_107113943 17.110 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_107048697 17.035 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_-_217263195 16.961 NM_001243505
ESRRG
estrogen-related receptor gamma
chr6_-_32557431 16.747 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr1_+_220863627 16.466 NM_024709
C1orf115
chromosome 1 open reading frame 115
chr1_+_104198301 16.206 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr22_+_22764094 16.177


chr10_-_98031154 16.066 NM_001114094
NM_013314
BLNK

B-cell linker

chr1_-_204380903 15.948 NM_032833
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr14_-_106573348 15.947 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr19_-_57336373 15.939 NM_001146186
PEG3
paternally expressed 3
chr3_+_109128836 15.916 NM_001145553
FLJ25363
uncharacterized LOC401082
chr1_-_160681552 15.772 NM_001778
CD48
CD48 molecule
chr1_-_149859465 15.638 NM_175065
HIST2H2AB
HIST2H2BE
histone cluster 2, H2ab
histone cluster 2, H2be
chr8_-_102803196 15.595 NCALD
neurocalcin delta
chr7_-_64023444 15.572


chr12_-_6772252 15.547 NM_001127582
NM_001127583
NM_001127584
NM_001127585
NM_001127586
NM_016162
ING4





inhibitor of growth family, member 4





chr14_-_106994001 15.487 IGHV3-48
IGH@
IGHA1
IGHM
immunoglobulin heavy variable 3-48
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr7_-_37488894 15.229 NM_001206480
ELMO1
engulfment and cell motility 1
chr5_-_39203061 15.056 FYB
FYN binding protein
chr12_-_9268522 14.937 NM_000014
A2M
alpha-2-macroglobulin
chr15_+_74422920 14.760 ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr7_-_76829109 14.711 NM_006682
FGL2
fibrinogen-like 2
chr15_+_25101697 14.682 NM_022805
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr1_+_66458389 14.665 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chr13_-_77460432 14.556 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr11_-_62369250 14.480 NM_004739
MTA2
metastasis associated 1 family, member 2
chr6_+_31588444 14.441 NM_004638
NM_080686
PRRC2A

proline-rich coiled-coil 2A

chr14_-_21270537 14.418 NM_198232
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr12_-_9268440 14.330 A2M
alpha-2-macroglobulin
chr1_+_50574589 14.303 NM_001144774
NM_021952
ELAVL4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

chr7_+_65419441 14.276 VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr20_-_52687014 14.242 BCAS1
breast carcinoma amplified sequence 1
chr12_+_58003962 14.234 NM_001111270
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr12_+_25205488 14.200 LRMP
lymphoid-restricted membrane protein
chr4_-_186733372 14.184 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr14_-_58764805 14.180 FLJ31306
uncharacterized LOC379025
chr2_+_226265601 13.991 NM_020864
NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr15_-_22473092 13.977


chr14_-_106539099 13.954 IGHA1
IGHG1
IGHG3
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_107122358 13.925


chr14_-_106926393 13.898 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106478129 13.742 IGHV4-31
IGHD
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr14_-_107078578 13.682


chr3_+_134514044 13.657 NM_004441
EPHB1
EPH receptor B1
chr17_-_38256905 13.614 NM_021724
NR1D1
nuclear receptor subfamily 1, group D, member 1
chr6_-_35656677 13.602 NM_001145776
NM_001145777
NM_004117
FKBP5


FK506 binding protein 5


chr5_-_160279045 13.483 NM_025153
ATP10B
ATPase, class V, type 10B
chr1_-_40157067 13.395 NM_016257
HPCAL4
hippocalcin like 4
chr9_+_125796845 13.280 NM_005294
GPR21
G protein-coupled receptor 21
chr19_-_4723755 13.231 DPP9
dipeptidyl-peptidase 9
chr1_+_192778168 13.190 NM_002923
RGS2
regulator of G-protein signaling 2, 24kDa
chr9_-_35618300 13.152 NM_001782
CD72
CD72 molecule
chr1_+_6052357 13.069 NM_001199861
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr14_-_106725620 13.053 IGHV4-31
IGHV3-23
IGHA1
IGHG1
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-23
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr20_+_17207596 13.033 NM_001201529
NM_002594
PCSK2

proprotein convertase subtilisin/kexin type 2

chr22_+_31742739 13.025 FLJ20464
uncharacterized protein FLJ20464
chr22_-_18923963 12.988 NM_001195226
NM_016335
PRODH

proline dehydrogenase (oxidase) 1

chr12_+_57522247 12.987 NM_002332
LRP1
low density lipoprotein receptor-related protein 1
chr6_+_37137882 12.917 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr2_+_68592317 12.890 NM_002664
PLEK
pleckstrin
chr5_-_24645084 12.856 NM_006727
CDH10
cadherin 10, type 2 (T2-cadherin)
chr6_+_31588523 12.759 PRRC2A
proline-rich coiled-coil 2A
chr8_+_19796730 12.734 LPL
lipoprotein lipase
chr15_+_62682682 12.682 TLN2
talin 2
chr14_-_106877689 12.679 IGHV4-31
IGH@
IGHA1
IGHA2
IGHG1
IGHG4
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 4 (G4m marker)
immunoglobulin heavy constant mu
chr5_-_39270708 12.667 NM_001243093
FYB
FYN binding protein
chr2_-_192015706 12.661 STAT4
signal transducer and activator of transcription 4
chr3_+_46395224 12.496 NM_001123041
NM_001123396
CCR2

chemokine (C-C motif) receptor 2


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.64 2.08e-22 GO:0048856 anatomical structure development
1.68 8.49e-22 GO:0048731 system development
1.44 2.44e-21 GO:0032501 multicellular organismal process
1.55 2.64e-21 GO:0032502 developmental process
1.59 3.35e-21 GO:0007275 multicellular organismal development
1.31 2.00e-20 GO:0065007 biological regulation
1.31 1.03e-18 GO:0050789 regulation of biological process
1.32 4.52e-18 GO:0050794 regulation of cellular process
1.50 9.28e-17 GO:0023052 signaling
1.89 1.29e-16 GO:0007399 nervous system development
1.70 3.32e-15 GO:0030154 cell differentiation
1.68 8.11e-15 GO:0048869 cellular developmental process
1.32 6.32e-14 GO:0050896 response to stimulus
1.16 1.58e-13 GO:0009987 cellular process
1.69 1.60e-13 GO:0048513 organ development
1.47 5.43e-13 GO:0007165 signal transduction
2.02 2.20e-12 GO:0022008 neurogenesis
1.59 2.51e-11 GO:0006355 regulation of transcription, DNA-dependent
2.14 3.43e-11 GO:0030182 neuron differentiation
1.54 9.92e-11 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.55 2.13e-10 GO:0051252 regulation of RNA metabolic process
1.49 3.44e-10 GO:0031326 regulation of cellular biosynthetic process
1.51 3.57e-10 GO:0010468 regulation of gene expression
1.62 4.49e-10 GO:0007166 cell surface receptor linked signaling pathway
1.51 4.57e-10 GO:0010556 regulation of macromolecule biosynthetic process
1.49 4.81e-10 GO:0009889 regulation of biosynthetic process
1.87 1.24e-09 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.94 1.25e-09 GO:0048699 generation of neurons
1.74 4.03e-09 GO:0002376 immune system process
1.40 5.92e-09 GO:0060255 regulation of macromolecule metabolic process
1.66 6.28e-09 GO:0009653 anatomical structure morphogenesis
1.57 7.70e-09 GO:0048583 regulation of response to stimulus
1.87 7.83e-09 GO:0050793 regulation of developmental process
1.46 8.17e-09 GO:0048518 positive regulation of biological process
1.35 8.19e-09 GO:0051716 cellular response to stimulus
1.39 9.98e-09 GO:0080090 regulation of primary metabolic process
2.20 1.64e-08 GO:0007417 central nervous system development
2.01 2.05e-08 GO:0045595 regulation of cell differentiation
1.70 2.15e-08 GO:0051239 regulation of multicellular organismal process
1.37 2.61e-08 GO:0031323 regulation of cellular metabolic process
1.84 3.02e-08 GO:0048468 cell development
1.45 3.79e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.09 4.34e-08 GO:0048666 neuron development
1.49 7.37e-08 GO:0042221 response to chemical stimulus
1.98 7.42e-08 GO:0010628 positive regulation of gene expression
2.54 8.49e-08 GO:0016337 cell-cell adhesion
1.84 1.14e-07 GO:0006351 transcription, DNA-dependent
1.91 1.22e-07 GO:0007155 cell adhesion
1.91 1.22e-07 GO:0022610 biological adhesion
1.91 1.57e-07 GO:2000026 regulation of multicellular organismal development
1.34 1.60e-07 GO:0019222 regulation of metabolic process
1.42 1.62e-07 GO:0051171 regulation of nitrogen compound metabolic process
1.81 6.87e-07 GO:0040011 locomotion
1.70 1.74e-06 GO:0010646 regulation of cell communication
1.55 1.78e-06 GO:0023051 regulation of signaling
1.83 4.21e-06 GO:0006955 immune response
2.32 4.66e-06 GO:0051093 negative regulation of developmental process
4.50 4.74e-06 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
2.93 5.32e-06 GO:0009952 anterior/posterior pattern formation
2.07 5.38e-06 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
3.01 7.04e-06 GO:0045165 cell fate commitment
1.69 7.35e-06 GO:0007154 cell communication
1.91 1.18e-05 GO:0009887 organ morphogenesis
1.84 1.21e-05 GO:0002682 regulation of immune system process
1.41 1.26e-05 GO:0048522 positive regulation of cellular process
1.89 1.46e-05 GO:0045893 positive regulation of transcription, DNA-dependent
2.08 1.50e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
2.19 1.62e-05 GO:0007420 brain development
1.69 1.80e-05 GO:0032774 RNA biosynthetic process
2.09 1.98e-05 GO:0007409 axonogenesis
1.76 2.10e-05 GO:0048584 positive regulation of response to stimulus
2.47 3.18e-05 GO:0003002 regionalization
1.96 5.75e-05 GO:0001775 cell activation
2.01 7.24e-05 GO:0048812 neuron projection morphogenesis
1.56 8.57e-05 GO:0009893 positive regulation of metabolic process
1.82 9.90e-05 GO:0030030 cell projection organization
1.94 1.07e-04 GO:0000904 cell morphogenesis involved in differentiation
1.58 1.15e-04 GO:0010604 positive regulation of macromolecule metabolic process
2.66 1.31e-04 GO:0030900 forebrain development
1.74 1.43e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.93 1.49e-04 GO:0031175 neuron projection development
2.89 1.58e-04 GO:0007156 homophilic cell adhesion
2.02 1.59e-04 GO:0016477 cell migration
1.78 1.99e-04 GO:0051254 positive regulation of RNA metabolic process
1.68 2.74e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.90 3.06e-04 GO:0048858 cell projection morphogenesis
1.67 3.46e-04 GO:0009891 positive regulation of biosynthetic process
1.50 3.68e-04 GO:0009966 regulation of signal transduction
1.71 3.87e-04 GO:0007267 cell-cell signaling
1.96 3.97e-04 GO:0032583 regulation of gene-specific transcription
1.88 4.33e-04 GO:0032990 cell part morphogenesis
2.34 4.97e-04 GO:0048568 embryonic organ development
2.10 5.35e-04 GO:0045597 positive regulation of cell differentiation
1.63 5.39e-04 GO:0009611 response to wounding
1.65 5.81e-04 GO:0009888 tissue development
1.70 6.43e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.93 6.49e-04 GO:0050776 regulation of immune response
1.88 7.04e-04 GO:0019226 transmission of nerve impulse
1.88 7.04e-04 GO:0035637 multicellular organismal signaling
1.68 7.46e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.59 1.01e-03 GO:0009605 response to external stimulus
1.91 1.08e-03 GO:0051094 positive regulation of developmental process
1.37 1.26e-03 GO:0048523 negative regulation of cellular process
1.81 1.64e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.80 1.77e-03 GO:0051253 negative regulation of RNA metabolic process
1.52 1.77e-03 GO:0031325 positive regulation of cellular metabolic process
2.07 1.89e-03 GO:0001501 skeletal system development
1.70 1.91e-03 GO:0009790 embryo development
1.74 1.91e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.87 2.37e-03 GO:0048870 cell motility
1.87 2.37e-03 GO:0051674 localization of cell
2.91 2.65e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
3.24 2.86e-03 GO:0048706 embryonic skeletal system development
1.74 3.11e-03 GO:0000902 cell morphogenesis
2.69 3.21e-03 GO:0001503 ossification
2.54 3.31e-03 GO:0048562 embryonic organ morphogenesis
1.34 3.32e-03 GO:0048519 negative regulation of biological process
1.69 3.47e-03 GO:0031327 negative regulation of cellular biosynthetic process
3.02 3.54e-03 GO:0050851 antigen receptor-mediated signaling pathway
2.20 3.60e-03 GO:0030097 hemopoiesis
1.72 4.37e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.14 4.41e-03 GO:0045596 negative regulation of cell differentiation
1.87 4.49e-03 GO:0007268 synaptic transmission
2.90 4.53e-03 GO:0002429 immune response-activating cell surface receptor signaling pathway
2.23 4.58e-03 GO:0002253 activation of immune response
1.75 6.00e-03 GO:0006928 cellular component movement
1.84 6.32e-03 GO:0008283 cell proliferation
1.70 6.49e-03 GO:0032989 cellular component morphogenesis
1.97 6.58e-03 GO:0007389 pattern specification process
1.78 6.76e-03 GO:0006935 chemotaxis
1.78 6.76e-03 GO:0042330 taxis
2.53 7.98e-03 GO:0001655 urogenital system development
1.65 8.16e-03 GO:0009890 negative regulation of biosynthetic process
1.93 8.46e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.99 9.35e-03 GO:0060284 regulation of cell development
2.16 1.04e-02 GO:0030168 platelet activation
1.77 1.08e-02 GO:0048585 negative regulation of response to stimulus
1.46 1.23e-02 GO:0010033 response to organic substance
1.90 1.32e-02 GO:0048598 embryonic morphogenesis
1.38 1.42e-02 GO:0003008 system process
3.05 1.45e-02 GO:0042063 gliogenesis
7.77 1.77e-02 GO:0021602 cranial nerve morphogenesis
1.71 1.82e-02 GO:0007186 G-protein coupled receptor protein signaling pathway
3.88 1.88e-02 GO:0048663 neuron fate commitment
1.72 2.03e-02 GO:0023056 positive regulation of signaling
3.29 2.44e-02 GO:0032526 response to retinoic acid
2.02 2.74e-02 GO:0048534 hemopoietic or lymphoid organ development
1.71 3.16e-02 GO:0010647 positive regulation of cell communication
1.66 3.21e-02 GO:0010629 negative regulation of gene expression
1.64 3.22e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.23 3.96e-02 GO:0002764 immune response-regulating signaling pathway
1.61 4.31e-02 GO:0009719 response to endogenous stimulus
1.98 4.47e-02 GO:0051960 regulation of nervous system development
1.80 4.62e-02 GO:0009968 negative regulation of signal transduction
1.31 4.76e-02 GO:0065008 regulation of biological quality
1.61 4.93e-02 GO:0010558 negative regulation of macromolecule biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.61 5.44e-14 GO:0044459 plasma membrane part
1.37 8.05e-12 GO:0005886 plasma membrane
1.36 3.53e-11 GO:0071944 cell periphery
1.71 1.02e-09 GO:0031226 intrinsic to plasma membrane
1.71 1.59e-09 GO:0005887 integral to plasma membrane
1.98 6.09e-05 GO:0043005 neuron projection
1.86 9.87e-04 GO:0045202 synapse
1.56 3.42e-03 GO:0005615 extracellular space
1.81 5.77e-03 GO:0009986 cell surface
1.46 6.63e-03 GO:0044421 extracellular region part
1.49 1.15e-02 GO:0042995 cell projection
1.96 2.09e-02 GO:0000785 chromatin

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.15 4.68e-19 GO:0001071 nucleic acid binding transcription factor activity
2.15 4.68e-19 GO:0003700 sequence-specific DNA binding transcription factor activity
2.39 5.59e-18 GO:0043565 sequence-specific DNA binding
1.87 2.85e-11 GO:0030528 transcription regulator activity
1.13 5.68e-11 GO:0005488 binding
1.46 2.34e-08 GO:0003677 DNA binding
4.75 3.28e-07 GO:0004879 ligand-dependent nuclear receptor activity
1.89 4.66e-07 GO:0005509 calcium ion binding
4.79 7.12e-07 GO:0003707 steroid hormone receptor activity
1.18 7.97e-06 GO:0005515 protein binding
1.39 8.21e-05 GO:0004871 signal transducer activity
1.39 8.21e-05 GO:0060089 molecular transducer activity
4.58 1.75e-04 GO:0003823 antigen binding
10.46 1.28e-03 GO:0003708 retinoic acid receptor activity
1.38 2.98e-03 GO:0004872 receptor activity
2.18 4.81e-03 GO:0000975 regulatory region DNA binding
2.18 4.81e-03 GO:0001067 regulatory region nucleic acid binding
2.18 4.81e-03 GO:0044212 transcription regulatory region DNA binding
1.22 6.20e-03 GO:0046872 metal ion binding
1.90 7.62e-03 GO:0016563 transcription activator activity
2.14 1.23e-02 GO:0010843 promoter binding
1.21 1.23e-02 GO:0043167 ion binding
3.33 1.60e-02 GO:0042562 hormone binding
1.20 1.73e-02 GO:0043169 cation binding
1.70 3.18e-02 GO:0008289 lipid binding
1.22 3.70e-02 GO:0003676 nucleic acid binding
1.43 3.98e-02 GO:0005102 receptor binding