Motif ID: RORA.p2

Z-value: 1.193


Transcription factors associated with RORA.p2:

Gene SymbolEntrez IDGene Name
RORA 6095 RAR-related orphan receptor A

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RORAchr15_-_615214780.432.0e-11Click!


Activity profile for motif RORA.p2.

activity profile for motif RORA.p2


Sorted Z-values histogram for motif RORA.p2

Sorted Z-values for motif RORA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RORA.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_49140569 22.558 NM_001352
DBP
D site of albumin promoter (albumin D-box) binding protein
chr10_-_52645384 17.731 A1CF
APOBEC1 complementation factor
chr12_-_42538432 16.620 NM_001099650
NM_173601
GXYLT1

glucoside xylosyltransferase 1

chr11_+_107461955 15.833 ELMOD1
ELMO/CED-12 domain containing 1
chr1_+_104198140 15.076 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr1_-_235812994 14.679 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr11_+_13299260 13.936 NM_001030272
NM_001030273
NM_001178
ARNTL


aryl hydrocarbon receptor nuclear translocator-like


chr4_-_186732208 13.464 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr6_-_152623213 13.382 SYNE1
spectrin repeat containing, nuclear envelope 1
chr11_+_13299372 13.059 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_+_13299376 12.766 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_+_13299349 12.543 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_+_107462073 12.252 ELMOD1
ELMO/CED-12 domain containing 1
chr16_-_1832571 12.110 SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr16_-_1832576 11.735 NM_080861
SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr5_-_134914968 11.733 NM_004887
CXCL14
chemokine (C-X-C motif) ligand 14
chr16_-_1832304 11.592 SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr19_+_1269244 11.208 NM_001280
CIRBP
cold inducible RNA binding protein
chr11_+_13299391 10.904 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_-_120008801 10.799 TRIM29
tripartite motif containing 29
chr8_-_134072404 9.970 NM_006748
SLA
Src-like-adaptor
chr11_+_13299329 9.819 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr6_-_136847743 9.176 NM_001198614
NM_001198618
NM_001198619
MAP7


microtubule-associated protein 7


chr12_-_56211503 8.861 SARNP
SAP domain containing ribonucleoprotein
chr7_+_101928417 7.758 SH2B2
SH2B adaptor protein 2
chr11_-_64527369 7.739 PYGM
phosphorylase, glycogen, muscle
chr1_+_17846818 7.436 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr6_+_43738757 7.251 VEGFA
vascular endothelial growth factor A
chr2_-_16081703 6.812 MYCNOS
MYCN opposite strand/antisense RNA (non-protein coding)
chr7_+_101928390 6.801 NM_020979
SH2B2
SH2B adaptor protein 2
chr2_+_121554866 6.528 NM_005270
GLI2
GLI family zinc finger 2
chr17_-_34308455 6.370 NM_004590
CCL16
chemokine (C-C motif) ligand 16
chr3_+_44596596 6.200 NM_018651
NM_025169
ZNF167

zinc finger protein 167

chr16_-_21831730 6.095 RRN3P1
RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
chr16_+_58534045 5.977 NM_001242833
NM_001242834
NM_001242835
NM_001242836
NDRG4



NDRG family member 4



chr11_-_2160199 5.962 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chr1_-_203155867 5.921 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chrX_-_71527000 5.884 NM_001144886
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr1_-_203155910 5.835 NM_001276
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr11_+_107461807 5.766 NM_001130037
NM_018712
ELMOD1

ELMO/CED-12 domain containing 1

chr1_+_104198301 5.670 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr1_-_104239071 5.651 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr10_-_52645430 5.650 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr2_-_154335181 5.505 NM_019845
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr3_+_1134619 5.201 NM_014461
CNTN6
contactin 6
chr13_-_27334777 5.167 NM_005288
GPR12
G protein-coupled receptor 12
chr11_-_67271839 4.894 PITPNM1
phosphatidylinositol transfer protein, membrane-associated 1
chr4_-_120243257 4.578 NM_000134
FABP2
fatty acid binding protein 2, intestinal
chr12_+_93963597 4.571 NM_003877
SOCS2
suppressor of cytokine signaling 2
chr11_-_2159784 4.549 IGF2
insulin-like growth factor 2 (somatomedin A)
chr16_+_27325269 4.539 IL4R
interleukin 4 receptor
chr5_-_154230157 4.467 C5orf4
chromosome 5 open reading frame 4
chr17_-_38859976 4.441 NM_019016
KRT24
keratin 24
chr5_+_66124603 4.284 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr8_-_120651019 4.048 NM_001040092
NM_001130863
NM_006209
ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr10_-_72141347 3.773 NM_207119
LRRC20
leucine rich repeat containing 20
chr19_+_50321503 3.736 NM_030973
MED25
mediator complex subunit 25
chr1_-_85155885 3.731 NM_001166295
NM_001166417
NM_001166293
NM_001166294
NM_014021
SSX2IP




synovial sarcoma, X breakpoint 2 interacting protein




chr2_+_27301434 3.701 NM_007046
EMILIN1
elastin microfibril interfacer 1
chr7_+_120969089 3.595 NM_057168
WNT16
wingless-type MMTV integration site family, member 16
chr22_+_41957011 3.568 NM_014460
CSDC2
cold shock domain containing C2, RNA binding
chr11_-_6462129 3.458 NM_000613
HPX
hemopexin
chr16_+_1832928 3.343 NM_012225
NUBP2
nucleotide binding protein 2
chr16_+_24266873 3.222 NM_006539
CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr13_-_52733995 3.212 NM_001146099
NM_002498
NEK3

NIMA (never in mitosis gene a)-related kinase 3

chr7_+_20655244 3.181 NM_001163941
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr6_-_155635562 3.067 TFB1M
transcription factor B1, mitochondrial
chr1_+_20396652 3.030 NM_000929
PLA2G5
phospholipase A2, group V
chr18_+_32073245 2.996 NM_001198945
NM_001392
NM_032975
NM_032979
DTNA



dystrobrevin, alpha



chr16_-_15188089 2.992 NM_018427
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr11_-_120008738 2.968 TRIM29
tripartite motif containing 29
chr14_+_92788924 2.867 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr6_+_32121228 2.859 NM_138717
PPT2
palmitoyl-protein thioesterase 2
chr1_-_151798552 2.855 NM_001001523
RORC
RAR-related orphan receptor C
chr4_+_110749149 2.724 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chrX_-_57147850 2.542 NM_001006681
NM_001006682
NM_001006683
SPIN2B


spindlin family, member 2B


chr19_+_58361219 2.524 ZNF587
zinc finger protein 587
chr6_-_34101272 2.504 NM_000841
GRM4
glutamate receptor, metabotropic 4
chr4_+_85504056 2.368 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr3_+_23987514 2.340 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr1_-_202896315 2.216 KLHL12
kelch-like 12 (Drosophila)
chr3_+_48488180 2.212 NM_032166
NM_130384
TREX1
ATRIP

three prime repair exonuclease 1
ATR interacting protein

chr2_+_139259476 2.175


chr19_+_42381189 2.173 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr11_-_72380107 2.170 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr12_+_2921786 2.159 NM_018463
ITFG2
integrin alpha FG-GAP repeat containing 2
chr13_+_109248499 2.148 NM_015011
MYO16
myosin XVI
chr2_+_171034654 2.115 NM_001083615
NM_001171642
NM_138995
MYO3B


myosin IIIB


chr11_-_73720281 1.996 NM_003356
NM_022803
UCP3

uncoupling protein 3 (mitochondrial, proton carrier)

chr19_+_8478181 1.991 NM_001005415
NM_001005416
NM_016496
MARCH2


membrane-associated ring finger (C3HC4) 2


chr17_+_26369617 1.924 NM_016231
NLK
nemo-like kinase
chr10_+_51549552 1.921 NM_002443
NM_138634
MSMB

microseminoprotein, beta-

chr17_+_40688264 1.907 NAGLU
N-acetylglucosaminidase, alpha
chr1_-_156786500 1.906 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr17_+_7554711 1.864 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr1_+_67632168 1.857 NM_144701
IL23R
interleukin 23 receptor
chr2_-_228497801 1.828 NM_001162483
NM_020161
C2orf83

chromosome 2 open reading frame 83

chr7_+_129008044 1.816 AHCYL2
adenosylhomocysteinase-like 2
chr6_-_111927082 1.806 TRAF3IP2
TRAF3 interacting protein 2
chr10_-_72362513 1.796 NM_001083116
NM_005041
PRF1

perforin 1 (pore forming protein)

chr10_+_18041217 1.783 NM_001098844
TMEM236
transmembrane protein 236
chr1_+_154966061 1.778 NM_018655
LENEP
lens epithelial protein
chr19_+_16059817 1.757 NM_001004465
OR10H4
olfactory receptor, family 10, subfamily H, member 4
chr7_+_97736118 1.751 NM_014916
LMTK2
lemur tyrosine kinase 2
chr19_+_57791794 1.743 NM_006635
ZNF460
zinc finger protein 460
chr1_-_173176314 1.726 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chrX_-_102774416 1.714 NM_080879
RAB40A
RAB40A, member RAS oncogene family
chr12_-_48119224 1.709 NM_001172439
NM_001172440
NM_006025
ENDOU


endonuclease, polyU-specific


chr17_+_73043319 1.707 KCTD2
potassium channel tetramerisation domain containing 2
chr11_-_2159472 1.674 IGF2
insulin-like growth factor 2 (somatomedin A)
chrX_-_62648209 1.614 LOC92249
uncharacterized LOC92249
chrX_-_32173585 1.607 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr10_-_72362441 1.607 PRF1
perforin 1 (pore forming protein)
chr11_-_102651321 1.606 NM_002425
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr1_-_203155827 1.573 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr18_+_32073343 1.573 DTNA
dystrobrevin, alpha
chr14_-_75389144 1.569 NM_031464
RPS6KL1
ribosomal protein S6 kinase-like 1
chr17_-_2304217 1.555 NM_020310
MNT
MAX binding protein
chr11_-_124806302 1.553 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr4_+_156824846 1.512 NM_005651
TDO2
tryptophan 2,3-dioxygenase
chr3_+_151531860 1.475 NM_001086
AADAC
arylacetamide deacetylase (esterase)
chr11_-_129062092 1.474 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr15_+_45422130 1.473 NM_017434
NM_175940
DUOX1

dual oxidase 1

chr13_-_103719195 1.440 NM_000452
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter family), member 2
chr1_+_111833473 1.439 NM_021797
NM_201653
CHIA

chitinase, acidic

chr11_+_131780537 1.425 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr15_-_77176191 1.415 NM_020843
SCAPER
S-phase cyclin A-associated protein in the ER
chr5_-_137071703 1.400 NM_017415
KLHL3
kelch-like 3 (Drosophila)
chr18_-_3874688 1.391 NM_001242762
NM_001242763
DLGAP1

discs, large (Drosophila) homolog-associated protein 1

chr6_-_30181197 1.380 NM_001242783
NM_003449
TRIM26

tripartite motif containing 26

chr16_-_90096308 1.357 NM_001214
C16orf3
chromosome 16 open reading frame 3
chr1_+_157963062 1.334 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr12_+_56623819 1.251 NM_173596
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr1_-_120311466 1.248 NM_001166107
NM_005518
HMGCS2

3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

chr17_+_40688189 1.246 NAGLU
N-acetylglucosaminidase, alpha
chr6_+_43737937 1.244 NM_001025366
NM_001025367
NM_001025368
NM_001025369
NM_001025370
NM_001033756
NM_001171622
NM_001171623
NM_001171624
NM_001171625
NM_001171626
NM_001171627
NM_001171628
NM_001171629
NM_001171630
NM_001204384
NM_001204385
NM_003376
VEGFA

















vascular endothelial growth factor A

















chr11_-_18258383 1.236 NM_006512
SAA4
serum amyloid A4, constitutive
chr6_-_155635611 1.227 NM_016020
TFB1M
transcription factor B1, mitochondrial
chr5_-_54830369 1.200 NM_003711
NM_176895
RNF138P1
PPAP2A

ring finger protein 138 pseudogene 1
phosphatidic acid phosphatase type 2A

chr6_+_42883726 1.179 NM_001243168
NM_001243169
NM_001243170
NM_138296
PTCRA



pre T-cell antigen receptor alpha



chr17_+_71161110 1.135 NM_001050
SSTR2
somatostatin receptor 2
chr11_+_71903172 1.122 NM_016729
FOLR1
folate receptor 1 (adult)
chr6_+_31913708 1.112 NM_001710
CFB
complement factor B
chr9_+_120466453 1.101 NM_138554
TLR4
toll-like receptor 4
chr7_-_126883568 1.094 NM_000845
GRM8
glutamate receptor, metabotropic 8
chr6_-_32634287 1.069 NM_001243961
NM_002123
HLA-DQB1

major histocompatibility complex, class II, DQ beta 1

chrX_-_2882288 1.064 NM_000047
ARSE
arylsulfatase E (chondrodysplasia punctata 1)
chr14_+_94492747 1.054 OTUB2
OTU domain, ubiquitin aldehyde binding 2
chr14_+_74815194 1.053 VRTN
vertebrae development homolog (pig)
chr12_-_53600999 1.045 NM_000889
ITGB7
integrin, beta 7
chr19_+_40093163 1.024 NM_013268
LGALS13
lectin, galactoside-binding, soluble, 13
chr19_-_10491172 1.001 TYK2
tyrosine kinase 2
chr11_-_119599253 0.968 NM_002855
NM_203285
NM_203286
PVRL1


poliovirus receptor-related 1 (herpesvirus entry mediator C)


chr8_-_82395401 0.963 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr15_+_40509628 0.958 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr13_+_102104941 0.937 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr10_+_102295700 0.923 HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr2_-_191872322 0.909 STAT1
signal transducer and activator of transcription 1, 91kDa
chr17_-_3499124 0.906 NM_080705
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr22_-_33402648 0.863 NM_003490
NM_133633
SYN3

synapsin III

chr10_+_102729249 0.842 SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr6_+_31913920 0.808 CFB
complement factor B
chr6_+_43738177 0.745 VEGFA
vascular endothelial growth factor A
chr15_-_78369825 0.726 NM_015079
NM_144572
TBC1D2B

TBC1 domain family, member 2B

chr3_+_132318980 0.720 NM_178445
CCRL1
chemokine (C-C motif) receptor-like 1
chr11_-_4629371 0.700 NM_018073
TRIM68
tripartite motif containing 68
chr4_+_39408472 0.688 NM_175737
KLB
klotho beta
chr2_-_37193609 0.654 NM_003162
STRN
striatin, calmodulin binding protein
chr17_+_32646058 0.619 NM_005623
CCL8
chemokine (C-C motif) ligand 8
chr6_+_121756744 0.609 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr12_-_10588543 0.605 NM_002260
KLRC2
KLRC3
killer cell lectin-like receptor subfamily C, member 2
killer cell lectin-like receptor subfamily C, member 3
chr12_-_57351381 0.605 NM_003708
RDH16
retinol dehydrogenase 16 (all-trans)
chr6_-_30128688 0.583 NM_006778
NM_052828
TRIM10

tripartite motif containing 10

chr6_+_43738394 0.564 VEGFA
vascular endothelial growth factor A
chr2_+_102927961 0.540 NM_016232
IL18R1
IL1RL1
interleukin 18 receptor 1
interleukin 1 receptor-like 1
chr6_-_110736748 0.539 NM_003649
NM_004032
DDO

D-aspartate oxidase

chr8_+_28174648 0.511 NM_006228
PNOC
prepronociceptin
chr17_+_26989193 0.506 SUPT6H
suppressor of Ty 6 homolog (S. cerevisiae)
chr3_-_184095927 0.490 NM_000460
NM_001177597
NM_001177598
THPO


thrombopoietin


chr10_+_101542554 0.487 ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chrX_+_12924738 0.452 NM_138636
TLR8
toll-like receptor 8
chrX_+_119495939 0.445 NM_001142447
NM_012069
ATP1B4

ATPase, Na+/K+ transporting, beta 4 polypeptide

chr1_+_46640748 0.439 NM_005727
TSPAN1
tetraspanin 1
chr22_+_21771661 0.433 NM_015094
HIC2
hypermethylated in cancer 2
chr2_+_233243243 0.413 NM_001632
ALPP
alkaline phosphatase, placental
chr12_-_56848398 0.410 NM_012064
MIP
major intrinsic protein of lens fiber
chr15_-_66084438 0.403 DENND4A
DENN/MADD domain containing 4A
chr19_+_55417507 0.374 NM_001145457
NM_001145458
NM_001242356
NM_001242357
NM_004829
NCR1




natural cytotoxicity triggering receptor 1




chr1_-_150602089 0.364 NM_004436
NM_207042
NM_207043
NM_207044
NM_207168
ENSA




endosulfine alpha




chr3_-_17741511 0.321 NM_001134381
TBC1D5
TBC1 domain family, member 5
chr8_+_17396285 0.317 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr11_+_5710816 0.218 NM_001199573
NM_006074
TRIM22

tripartite motif containing 22

chr5_+_64859098 0.207 NM_015342
PPWD1
peptidylprolyl isomerase domain and WD repeat containing 1
chr1_-_19217384 0.189 NM_001161504
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr19_-_51220194 0.176 NM_016148
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr1_+_178310605 0.168 NM_004841
RASAL2
RAS protein activator like 2
chr6_-_35696359 0.156 NM_001145775
FKBP5
FK506 binding protein 5
chrX_-_24690740 0.151 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr7_-_107880492 0.135 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr2_-_216003068 0.133 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.69 2.75e-04 GO:0002376 immune system process
3.12 1.63e-03 GO:0006955 immune response
10.73 1.59e-02 GO:0051591 response to cAMP
1.36 2.39e-02 GO:0065007 biological regulation
1.64 2.92e-02 GO:0023052 signaling
36.19 4.96e-02 GO:0002532 production of molecular mediator involved in inflammatory response

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.14 5.17e-05 GO:0044459 plasma membrane part
1.56 9.02e-03 GO:0005886 plasma membrane
1.54 1.40e-02 GO:0071944 cell periphery
2.17 1.77e-02 GO:0005887 integral to plasma membrane
2.13 2.39e-02 GO:0031226 intrinsic to plasma membrane

Nothing significant found in function category.