• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: RXRG_dimer.p3

Z-value: 1.878

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_+_96252770	50.645		SNRPF	small nuclear ribonucleoprotein polypeptide F
chr7_-_65447233	39.587	NM_000181	GUSB	glucuronidase, beta
chr7_-_65447187	38.968		GUSB	glucuronidase, beta
chr12_+_96252705	38.861	NM_003095	SNRPF	small nuclear ribonucleoprotein polypeptide F
chr7_-_65447206	37.729		GUSB	glucuronidase, beta
chr7_-_65447162	36.059		GUSB	glucuronidase, beta
chr7_-_139763520	35.402	NM_022750	PARP12	poly (ADP-ribose) polymerase family, member 12
chr2_+_109237679	35.294	NM_001193484	LIMS1	LIM and senescent cell antigen-like domains 1
chr8_-_80942488	34.893	NM_014018	MRPS28	mitochondrial ribosomal protein S28
chr3_-_150264134	33.262		SERP1	stress-associated endoplasmic reticulum protein 1
chr3_-_113465101	32.963	NM_025146	NAA50	N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr2_-_64246431	32.858		VPS54	vacuolar protein sorting 54 homolog (S. cerevisiae)
chr7_-_72936538	32.414		BAZ1B	bromodomain adjacent to zinc finger domain, 1B
chr1_-_40042461	31.331		PABPC4	poly(A) binding protein, cytoplasmic 4 (inducible form)
chr1_-_40042519	29.517	NM_001135653 NM_001135654 NM_003819	PABPC4	poly(A) binding protein, cytoplasmic 4 (inducible form)
chr12_+_67663364	29.234		CAND1	cullin-associated and neddylation-dissociated 1
chr2_+_178257371	28.991	NM_003659	AGPS	alkylglycerone phosphate synthase
chr19_-_2328566	27.498	NM_016199	LSM7	LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_+_207024317	25.387	NM_001037663 NM_001959 NM_021121	EEF1B2	eukaryotic translation elongation factor 1 beta 2
chr2_+_207024614	25.152		EEF1B2	eukaryotic translation elongation factor 1 beta 2
chr2_+_178257488	23.913		AGPS	alkylglycerone phosphate synthase
chr2_-_176046120	22.856	NM_001002258 NM_001190329 NM_001689	ATP5G3	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr3_-_113464991	22.400		NAA50	N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr2_+_120125141	22.321	NM_001079863	DBI	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr3_-_150264234	21.896		SERP1	stress-associated endoplasmic reticulum protein 1
chr14_-_75643335	20.361	NM_006827	TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr2_-_198364522	20.054		HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr6_-_31926628	19.681	NM_002904	RDBP	RD RNA binding protein
chr20_-_32899607	19.680	NM_001161766	AHCY	adenosylhomocysteinase
chr2_-_207024103	19.090	NM_001199981 NM_001199982 NM_001199983 NM_005006	NDUFS1	NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr4_-_7069755	18.741	NM_025196	GRPEL1	GrpE-like 1, mitochondrial (E. coli)
chr7_-_74489636	18.651		WBSCR16	Williams-Beuren syndrome chromosome region 16
chr2_-_198364560	18.210		HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr14_-_75643309	17.997		TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr2_+_207024330	17.465		EEF1B2	eukaryotic translation elongation factor 1 beta 2
chr14_-_75643286	17.107		TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr12_+_67663147	16.841		CAND1	cullin-associated and neddylation-dissociated 1
chr16_-_47007567	16.728	NM_005880	DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2
chrX_-_153191686	16.292		ARHGAP4	Rho GTPase activating protein 4
chr14_-_75643333	16.276		TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr1_-_43855448	16.059		MED8	mediator complex subunit 8
chr16_-_47007483	15.695		DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2
chr19_+_10362912	15.309		MRPL4	mitochondrial ribosomal protein L4
chr2_+_109065576	14.895	NM_181453	GCC2	GRIP and coiled-coil domain containing 2
chr2_-_198364997	14.208	NM_199440	HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr2_+_198365113	13.651		HSPE1	heat shock 10kDa protein 1 (chaperonin 10)
chr14_-_95623665	13.505	NM_177438	DICER1	dicer 1, ribonuclease type III
chr4_-_7069801	13.493		GRPEL1	GrpE-like 1, mitochondrial (E. coli)
chr3_-_150264280	13.355	NM_014445	SERP1	stress-associated endoplasmic reticulum protein 1
chr17_+_41150465	13.025		RPL27	ribosomal protein L27
chr1_-_40042415	12.859		PABPC4	poly(A) binding protein, cytoplasmic 4 (inducible form)
chr12_-_7079616	12.854		PHB2	prohibitin 2
chr17_+_7123246	12.616		ACADVL	acyl-CoA dehydrogenase, very long chain
chr14_-_106174914	12.589		IGHA1	immunoglobulin heavy constant alpha 1
chr7_+_143079354	12.266		ZYX	zyxin
chr2_-_198364623	12.251	NM_002156	HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr17_+_41150409	11.958	NM_000988	RPL27	ribosomal protein L27
chr5_+_1801493	11.709	NM_004553	NDUFS6	NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
chr2_+_120124828	11.537	NM_001178017	DBI	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr12_+_14538232	11.510		ATF7IP	activating transcription factor 7 interacting protein
chr12_+_67663060	11.472	NM_018448	CAND1	cullin-associated and neddylation-dissociated 1
chr22_+_30163351	11.470	NM_001003684 NM_013387	UQCR10	ubiquinol-cytochrome c reductase, complex III subunit X
chr12_-_118810712	11.319	NM_016281	TAOK3	TAO kinase 3
chr2_+_198365012	11.154		HSPE1	heat shock 10kDa protein 1 (chaperonin 10)
chrX_-_153191710	11.104	NM_001164741 NM_001666	ARHGAP4	Rho GTPase activating protein 4
chr2_+_28113598	11.085		BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)
chr4_+_109541721	11.049	NM_000995 NM_033625	RPL34	ribosomal protein L34
chr7_+_143079925	10.971		ZYX	zyxin
chr22_-_24059436	10.925
chr6_+_143999058	10.925	NM_001100164 NM_001100165	PHACTR2	phosphatase and actin regulator 2
chr11_+_118230348	10.920		UBE4A	ubiquitination factor E4A
chr3_-_150264264	10.874		SERP1	stress-associated endoplasmic reticulum protein 1
chr19_+_10362886	10.810		MRPL4	mitochondrial ribosomal protein L4
chr2_+_198364720	10.682	NM_001202485 NM_002157	HSPE1-MOB4 HSPE1	HSPE1-MOB4 readthrough heat shock 10kDa protein 1 (chaperonin 10)
chr7_-_107204705	10.588	NM_001161520 NM_006348 NM_181733	COG5	component of oligomeric golgi complex 5
chr20_+_44509847	10.516	NM_080603	ZSWIM1	zinc finger, SWIM-type containing 1
chr1_-_155881163	10.230	NM_006912	RIT1	Ras-like without CAAX 1
chr4_+_140587086	10.189		MGST2	microsomal glutathione S-transferase 2
chr20_+_30945988	9.918	NM_001164603 NM_015338	ASXL1	additional sex combs like 1 (Drosophila)
chr12_+_69004684	9.172		RAP1B	RAP1B, member of RAS oncogene family
chr6_+_31623668	9.140	NM_019101	APOM	apolipoprotein M
chrX_-_122866881	9.113		THOC2	THO complex 2
chr12_+_69004710	9.091		RAP1B	RAP1B, member of RAS oncogene family
chr7_-_74489572	9.053		WBSCR16	Williams-Beuren syndrome chromosome region 16
chrX_-_153191644	8.865		ARHGAP4	Rho GTPase activating protein 4
chr6_-_2840683	8.606		SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr12_+_50135953	8.157		TMBIM6	transmembrane BAX inhibitor motif containing 6
chr11_+_118230292	8.128	NM_001204077 NM_004788	UBE4A	ubiquitination factor E4A
chr1_-_6761839	8.003		DNAJC11	DnaJ (Hsp40) homolog, subfamily C, member 11
chr12_+_132413776	7.982	NM_001002019 NM_025215	PUS1	pseudouridylate synthase 1
chr7_-_74489686	7.762	NM_030798	WBSCR16	Williams-Beuren syndrome chromosome region 16
chr16_+_4714709	7.679		MGRN1	mahogunin, ring finger 1
chr3_+_37284680	7.317	NM_001172713 NM_002078	GOLGA4	golgin A4
chr1_-_226374401	7.123	NM_022735	ACBD3	acyl-CoA binding domain containing 3
chr16_+_4475804	7.042	NM_001135110 NM_005147	DNAJA3	DnaJ (Hsp40) homolog, subfamily A, member 3
chr16_+_2255708	6.898	NM_001199174	MLST8	MTOR associated protein, LST8 homolog (S. cerevisiae)
chr1_-_155881063	6.809		RIT1	Ras-like without CAAX 1
chr2_+_109065665	6.764		GCC2	GRIP and coiled-coil domain containing 2
chr11_+_118443140	6.556		ARCN1	archain 1
chr12_+_69004614	6.278	NM_001010942 NM_001251917 NM_001251918 NM_001251921 NM_001251922 NM_015646	RAP1B	RAP1B, member of RAS oncogene family
chr12_-_51422012	6.263	NM_001174125	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr11_-_66206260	6.154	NM_016050 NM_170738 NM_170739	MRPL11	mitochondrial ribosomal protein L11
chr15_+_57210823	5.974	NM_003205 NM_207036 NM_207037 NM_207038	TCF12	transcription factor 12
chr6_+_31623688	5.921		APOM	apolipoprotein M
chr19_+_45394642	5.897		TOMM40	translocase of outer mitochondrial membrane 40 homolog (yeast)
chr1_-_40042072	5.736		PABPC4	poly(A) binding protein, cytoplasmic 4 (inducible form)
chr10_-_103815868	5.699	NM_024541	C10orf76	chromosome 10 open reading frame 76
chr6_+_33172418	5.450	NM_014234	HSD17B8	hydroxysteroid (17-beta) dehydrogenase 8
chr1_-_6761878	5.450		DNAJC11	DnaJ (Hsp40) homolog, subfamily C, member 11
chr22_+_20105076	5.336		RANBP1	RAN binding protein 1
chr11_+_86013252	5.311	NM_016401	C11orf73	chromosome 11 open reading frame 73
chrY_-_1460901	5.304	NM_001636	SLC25A6	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr1_-_193075186	5.158	NM_001243399 NM_016066	GLRX2	glutaredoxin 2
chr2_+_86668270	5.125	NM_018433	KDM3A	lysine (K)-specific demethylase 3A
chr12_+_132413743	5.017	NM_001002020	PUS1	pseudouridylate synthase 1
chr11_-_14386051	4.996	NM_001177314	RRAS2	related RAS viral (r-ras) oncogene homolog 2
chr2_-_24307179	4.970	NM_001206802	TP53I3	tumor protein p53 inducible protein 3
chr15_+_57210852	4.965		TCF12	transcription factor 12
chr19_+_11546938	4.923		PRKCSH	protein kinase C substrate 80K-H
chr13_+_21714709	4.890		SAP18	Sin3A-associated protein, 18kDa
chr6_-_108395939	4.773	NM_014028	OSTM1	osteopetrosis associated transmembrane protein 1
chr6_+_143771779	4.733	NM_003630	PEX3	peroxisomal biogenesis factor 3
chr7_-_25164902	4.721	NM_018947	CYCS	cytochrome c, somatic
chr1_+_154947166	4.669		CKS1B	CDC28 protein kinase regulatory subunit 1B
chr3_-_49449525	4.556	NM_001664	RHOA	ras homolog gene family, member A
chr20_-_20033005	4.414		CRNKL1	crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
chr11_+_118443091	4.399	NM_001142281 NM_001655	ARCN1	archain 1
chr5_+_42548314	4.398	NM_001242403	GHR	growth hormone receptor
chr8_+_22436641	4.336		PDLIM2	PDZ and LIM domain 2 (mystique)
chr17_-_2614926	4.302	NM_015229	KIAA0664	KIAA0664
chr4_-_72671236	4.155	NM_001204306	GC	group-specific component (vitamin D binding protein)
chrX_-_122866888	3.772	NM_001081550	THOC2	THO complex 2
chr1_-_6761897	3.718	NM_018198	DNAJC11	DnaJ (Hsp40) homolog, subfamily C, member 11
chr1_+_154947147	3.662		CKS1B	CDC28 protein kinase regulatory subunit 1B
chr22_+_20105068	3.655		RANBP1	RAN binding protein 1
chr7_+_129015483	3.531	NM_001130722	AHCYL2	adenosylhomocysteinase-like 2
chr1_+_151138497	3.525	NM_001204856 NM_024041	SCNM1	sodium channel modifier 1
chr18_-_47339854	3.483		ACAA2	acetyl-CoA acyltransferase 2
chr1_+_43148359	3.411		YBX1	Y box binding protein 1
chr1_+_154947116	3.389	NM_001826	CKS1B	CDC28 protein kinase regulatory subunit 1B
chr19_+_11546485	3.329		PRKCSH	protein kinase C substrate 80K-H
chr17_+_40440481	3.147		STAT5A	signal transducer and activator of transcription 5A
chr17_+_7123149	3.144	NM_000018 NM_001033859	ACADVL	acyl-CoA dehydrogenase, very long chain
chr17_+_7812703	3.117		CHD3	chromodomain helicase DNA binding protein 3
chr15_+_57210972	3.008		TCF12	transcription factor 12
chr3_-_12881948	2.995	NM_001007074	RPL32	ribosomal protein L32
chr2_-_74756824	2.977		AUP1	ancient ubiquitous protein 1
chr22_+_20105095	2.820		RANBP1	RAN binding protein 1
chr3_-_49449393	2.814		RHOA	ras homolog gene family, member A
chr7_-_25164869	2.777		CYCS	cytochrome c, somatic
chr22_-_24059502	2.772		GUSBP11	glucuronidase, beta pseudogene 11
chr1_-_19578030	2.688		KIAA0090	KIAA0090
chrX_-_1510901	2.684	NM_001636	SLC25A6	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr20_-_36661822	2.669	NM_014657	TTI1	TELO2 interacting protein 1
chr15_-_82554990	2.660		EFTUD1	elongation factor Tu GTP binding domain containing 1
chr3_-_194392913	2.650		LSG1	large subunit GTPase 1 homolog (S. cerevisiae)
chr2_+_28113612	2.575		BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)
chr15_-_82555076	2.507	NM_001040610 NM_024580	EFTUD1	elongation factor Tu GTP binding domain containing 1
chr19_+_54606141	2.440	NM_004542	NDUFA3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr10_+_22605300	2.320	NM_001204062 NM_012071	COMMD3-BMI1 COMMD3	COMMD3-BMI1 readthrough COMM domain containing 3
chr6_-_108395854	2.254		OSTM1	osteopetrosis associated transmembrane protein 1
chr11_+_86748870	2.239	NM_001168724 NM_022918	TMEM135	transmembrane protein 135
chr19_+_10197023	2.176		C19orf66	chromosome 19 open reading frame 66
chr6_-_108395923	1.965		OSTM1	osteopetrosis associated transmembrane protein 1
chr22_-_19166133	1.915		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr19_+_50016435	1.834	NM_004107	FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr6_-_108395918	1.791		OSTM1	osteopetrosis associated transmembrane protein 1
chr11_+_117049838	1.790	NM_001040455	SIDT2	SID1 transmembrane family, member 2
chr5_-_74807448	1.769	NM_005713 NM_031361	COL4A3BP	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr22_-_19166276	1.755		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr1_-_19578015	1.686		KIAA0090	KIAA0090
chr1_-_6420719	1.683	NM_181865	ACOT7	acyl-CoA thioesterase 7
chr18_+_29598444	1.674	NM_017831	RNF125	ring finger protein 125
chr1_+_145727665	1.645	NM_001201325 NM_001201326 NM_002614	PDZK1	PDZ domain containing 1
chr4_-_4543747	1.621	NM_016930	STX18	syntaxin 18
chr1_+_145727712	1.592		PDZK1	PDZ domain containing 1
chr1_-_32860014	1.565	NM_001143888 NM_001143889 NM_001143890 NM_018045	BSDC1	BSD domain containing 1
chr7_+_99933734	1.553		PILRB	paired immunoglobin-like type 2 receptor beta
chr19_+_45394459	1.540	NM_001128916 NM_001128917 NM_006114	TOMM40	translocase of outer mitochondrial membrane 40 homolog (yeast)
chr7_-_134855383	1.485		C7orf49	chromosome 7 open reading frame 49
chr1_-_211848820	1.460	NM_001204182 NM_001204183 NM_002497	NEK2	NIMA (never in mitosis gene a)-related kinase 2
chr19_+_10196972	1.401		C19orf66	chromosome 19 open reading frame 66
chr6_+_7107799	1.395	NM_001168344	RREB1	ras responsive element binding protein 1
chr19_+_11546085	1.387	NM_001001329 NM_002743	PRKCSH	protein kinase C substrate 80K-H
chr7_-_134855237	1.372	NM_001243752	C7orf49	chromosome 7 open reading frame 49
chr20_-_34542205	1.314		SCAND1	SCAN domain containing 1
chr12_+_49716970	1.307	NM_001100620 NM_005480	TROAP	trophinin associated protein (tastin)
chr1_-_154946801	1.295		SHC1	SHC (Src homology 2 domain containing) transforming protein 1
chr10_-_119805673	1.280	NM_014904	RAB11FIP2	RAB11 family interacting protein 2 (class I)
chr2_-_20251788	1.241	NM_014713	LAPTM4A	lysosomal protein transmembrane 4 alpha
chr3_-_194393205	1.236	NM_018385	LSG1	large subunit GTPase 1 homolog (S. cerevisiae)
chr11_-_61658853	1.192	NM_021727	FADS3	fatty acid desaturase 3
chr22_-_24059524	1.191		GUSBP11	glucuronidase, beta pseudogene 11
chr1_-_203144910	1.185	NM_004997	MYBPH	myosin binding protein H
chr12_+_6309475	1.142	NM_001769	CD9	CD9 molecule
chr4_-_4543690	1.141		STX18	syntaxin 18
chr10_+_75504119	1.094	NM_004922 NM_198597	SEC24C	SEC24 family, member C (S. cerevisiae)
chr8_+_67624652	1.035	NM_001033578	SGK3	serum/glucocorticoid regulated kinase family, member 3
chr3_-_194392881	1.030		LSG1	large subunit GTPase 1 homolog (S. cerevisiae)
chr9_+_115142395	1.020		HSDL2	hydroxysteroid dehydrogenase like 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.64	3.60e-05	GO:0044237	cellular metabolic process
1.54	2.10e-04	GO:0008152	metabolic process
1.54	2.52e-03	GO:0044238	primary metabolic process
5.86	6.60e-03	GO:0006457	protein folding
1.94	2.17e-02	GO:0009058	biosynthetic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.83	9.01e-10	GO:0044444	cytoplasmic part
3.25	3.04e-08	GO:0005739	mitochondrion
1.54	1.10e-07	GO:0005737	cytoplasm
3.70	3.77e-05	GO:0044429	mitochondrial part
1.30	4.95e-05	GO:0044424	intracellular part
1.27	1.40e-04	GO:0005622	intracellular
4.07	3.35e-04	GO:0005740	mitochondrial envelope
4.89	4.48e-04	GO:0005743	mitochondrial inner membrane
3.99	9.09e-04	GO:0031966	mitochondrial membrane
1.57	9.61e-04	GO:0044446	intracellular organelle part
1.37	9.91e-04	GO:0043231	intracellular membrane-bounded organelle
1.37	1.05e-03	GO:0043227	membrane-bounded organelle
4.48	1.15e-03	GO:0019866	organelle inner membrane
2.11	1.22e-03	GO:0031090	organelle membrane
1.55	1.68e-03	GO:0044422	organelle part
1.29	8.63e-03	GO:0043229	intracellular organelle
1.29	9.49e-03	GO:0043226	organelle
4.48	1.36e-02	GO:0005759	mitochondrial matrix
2.85	1.61e-02	GO:0031967	organelle envelope
2.80	1.99e-02	GO:0031975	envelope
1.64	3.14e-02	GO:0032991	macromolecular complex
8.48	4.91e-02	GO:0070469	respiratory chain

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.48	2.04e-04	GO:0005515	protein binding
29.83	1.26e-03	GO:0000062	fatty-acyl-CoA binding
7.92	1.27e-03	GO:0051082	unfolded protein binding
15.12	3.00e-03	GO:0005504	fatty acid binding
9.99	2.30e-02	GO:0033293	monocarboxylic acid binding
74.56	3.84e-02	GO:0004013	adenosylhomocysteinase activity
74.56	3.84e-02	GO:0016802	trialkylsulfonium hydrolase activity