Motif ID: SNAI1..3.p2

Z-value: 3.330


Transcription factors associated with SNAI1..3.p2:

Gene SymbolEntrez IDGene Name
SNAI1 6615 snail homolog 1 (Drosophila)
SNAI2 6591 snail homolog 2 (Drosophila)
SNAI3 333929 snail homolog 3 (Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SNAI2chr8_-_49833823-0.497.4e-15Click!
SNAI1chr20_+_485995110.488.8e-14Click!


Activity profile for motif SNAI1..3.p2.

activity profile for motif SNAI1..3.p2


Sorted Z-values histogram for motif SNAI1..3.p2

Sorted Z-values for motif SNAI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SNAI1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_38755238 78.185 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_38755422 75.620 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_38755097 71.974 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr17_-_7165788 53.983 CLDN7
claudin 7
chr19_-_12886263 45.102 HOOK2
hook homolog 2 (Drosophila)
chr15_-_76030958 44.525 DNM1P35
DNM1 pseudogene 35
chr17_-_7166263 41.292 NM_001185023
NM_001307
CLDN7

claudin 7

chr11_-_68518910 39.760 MTL5
metallothionein-like 5, testis-specific (tesmin)
chr9_-_97401588 35.812 FBP1
fructose-1,6-bisphosphatase 1
chr14_-_61748510 34.501 NM_001017970
TMEM30B
transmembrane protein 30B
chr6_-_136871542 33.739 MAP7
microtubule-associated protein 7
chr9_-_97401746 33.062 FBP1
fructose-1,6-bisphosphatase 1
chr1_+_60280462 31.429 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr14_-_61747956 31.139 TMEM30B
transmembrane protein 30B
chr1_+_1981902 30.603 NM_002744
PRKCZ
protein kinase C, zeta
chr14_+_75745480 29.271 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr22_+_22697538 28.768


chr19_-_12886421 28.672 NM_001100176
NM_013312
HOOK2

hook homolog 2 (Drosophila)

chr16_+_68771214 28.503 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr16_+_68771192 27.885 NM_004360
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr22_-_19511777 27.742 CLDN5
claudin 5
chr14_+_92788924 27.521 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr6_+_31783530 27.465 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr9_-_97401833 27.380 NM_000507
FBP1
fructose-1,6-bisphosphatase 1
chr11_+_130029773 27.312 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr16_-_4987056 26.832 NM_002705
PPL
periplakin
chr15_+_44581045 26.390 CASC4
cancer susceptibility candidate 4
chr15_+_44580954 26.375 CASC4
cancer susceptibility candidate 4
chr1_-_111746917 25.245 DENND2D
DENN/MADD domain containing 2D
chr1_-_52831817 25.038 NM_032449
CC2D1B
coiled-coil and C2 domain containing 1B
chr6_+_31783314 24.361 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr19_+_14017038 24.213 CC2D1A
coiled-coil and C2 domain containing 1A
chrX_-_107018889 23.916 TSC22D3
TSC22 domain family, member 3
chr7_-_73184535 23.895 NM_001306
CLDN3
claudin 3
chr17_-_39942937 23.884 NM_002230
NM_021991
JUP

junction plakoglobin

chr7_-_8301767 23.640 NM_001136020
ICA1
islet cell autoantigen 1, 69kDa
chr11_+_121322848 23.102 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr1_+_3371020 22.387 NM_014448
ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr1_-_59042827 22.170 TACSTD2
tumor-associated calcium signal transducer 2
chr19_+_18794487 21.815 CRTC1
CREB regulated transcription coactivator 1
chr11_+_130029712 21.698 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr2_+_64751436 21.383 NM_001002243
NM_017657
NM_203437
AFTPH


aftiphilin


chr17_+_73521744 21.243 NM_001015002
NM_001031803
NM_004524
LLGL2


lethal giant larvae homolog 2 (Drosophila)


chr6_-_136871956 21.214 NM_001198616
NM_001198617
NM_003980
MAP7


microtubule-associated protein 7


chr1_+_156030965 21.094 NM_020387
RAB25
RAB25, member RAS oncogene family
chr15_+_50474357 20.994 NM_001159629
NM_003645
SLC27A2

solute carrier family 27 (fatty acid transporter), member 2

chr14_-_106539099 20.811 IGHA1
IGHG1
IGHG3
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr5_-_43412417 20.683 NM_148672
CCL28
chemokine (C-C motif) ligand 28
chr14_-_106208695 20.547


chr19_+_35739778 20.315 LSR
lipolysis stimulated lipoprotein receptor
chr17_+_72744802 20.290 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr1_+_46646199 19.774 TSPAN1
tetraspanin 1
chr17_+_72744794 19.681 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr8_+_102504836 19.660 GRHL2
grainyhead-like 2 (Drosophila)
chr12_+_51318743 19.571 METTL7A
methyltransferase like 7A
chr11_+_61129831 19.243 TMEM138
transmembrane protein 138
chr1_+_183155393 19.180 LAMC2
laminin, gamma 2
chr19_+_39899749 19.107


chr11_+_118401873 19.017 TMEM25
transmembrane protein 25
chr22_+_23165273 18.863


chr5_-_1295022 18.518 NM_001193376
NM_198253
TERT

telomerase reverse transcriptase

chr2_-_166650770 18.382 NM_004482
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr6_+_31795395 18.357 NM_005346
HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr19_+_35739282 18.221 LSR
lipolysis stimulated lipoprotein receptor
chr19_+_35739519 18.096 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor


chr7_-_99680358 18.055 ZNF3
zinc finger protein 3
chr22_+_23010757 17.903


chrX_-_107019001 17.701 NM_198057
TSC22D3
TSC22 domain family, member 3
chr22_+_22735134 17.688 CYAT1
immunoglobulin lambda light chain-like
chr2_-_24583291 17.590 NM_006277
NM_019595
NM_147152
ITSN2


intersectin 2


chr17_+_72744746 17.578 NM_004252
SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr14_-_106208537 17.444


chr6_-_137113166 17.278


chr2_+_219283809 17.268 NM_007127
VIL1
villin 1
chr13_+_48877950 17.266 RB1
retinoblastoma 1
chr15_+_41136622 17.214 NM_001032367
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr8_-_99306563 17.208 NM_024759
NIPAL2
NIPA-like domain containing 2
chr3_+_101395299 17.074 LOC100009676
uncharacterized LOC100009676
chr4_-_57522469 17.027 NM_001145459
NM_139211
HOPX

HOP homeobox

chr15_+_41136178 16.996 NM_003710
NM_181642
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr22_+_38453478 16.953 PICK1
protein interacting with PRKCA 1
chr19_-_18632857 16.837 ELL
elongation factor RNA polymerase II
chr2_-_241835572 16.828 NM_001085437
C2orf54
chromosome 2 open reading frame 54
chr14_-_55369163 16.683 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr17_+_38119225 16.666 NM_178171
GSDMA
gasdermin A
chr10_-_21462987 16.392 NEBL
nebulette
chr4_-_657424 16.181


chr6_-_36355342 16.092 NM_001207038
NM_001207035
NM_001207036
NM_001207037
NM_001207039
NM_001207040
NM_001207041
NM_016135
ETV7







ets variant 7







chr17_+_5972425 16.074 WSCD1
WSC domain containing 1
chr17_-_31203889 15.604 NM_015194
MYO1D
myosin ID
chr22_+_22712091 15.534 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr7_+_16793320 15.411 NM_014399
TSPAN13
tetraspanin 13
chr11_+_130029663 15.321 NM_021978
ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr1_-_182361311 15.320 NM_001033044
NM_002065
GLUL

glutamate-ammonia ligase

chr1_-_201368434 15.270 LAD1
ladinin 1
chr12_-_6484904 15.224 NM_001038
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr1_-_201368716 15.220 LAD1
ladinin 1
chr2_-_89513056 15.152 IGKC
immunoglobulin kappa constant
chr8_+_102504661 15.132 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr17_+_72744775 15.074 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr11_-_64856541 14.969 NM_001242631
LOC100130348
LOC399904
uncharacterized LOC100130348
uncharacterized LOC399904
chr2_+_47596447 14.963 EPCAM
epithelial cell adhesion molecule
chr6_+_37137882 14.944 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr21_-_42219038 14.878 NM_001389
DSCAM
Down syndrome cell adhesion molecule
chr2_-_224702200 14.789 AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr11_+_44587212 14.721 CD82
CD82 molecule
chr19_-_14016908 14.703 NM_024323
C19orf57
chromosome 19 open reading frame 57
chr2_-_25467078 14.649 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr8_+_95653272 14.637 ESRP1
epithelial splicing regulatory protein 1
chr7_-_8301681 14.611 NM_022307
ICA1
islet cell autoantigen 1, 69kDa
chr7_-_8302141 14.553 NM_004968
ICA1
islet cell autoantigen 1, 69kDa
chr19_-_18632886 14.537 NM_006532
ELL
elongation factor RNA polymerase II
chr12_-_33049664 14.490 NM_001005242
NM_004572
PKP2

plakophilin 2

chr6_-_62995852 14.477 NM_152688
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr3_+_47021146 14.380 NM_015175
NBEAL2
neurobeachin-like 2
chrX_-_13956445 14.322


chr5_+_68788387 14.242 NM_001205254
OCLN
occludin
chr19_+_14017044 14.178 CC2D1A
coiled-coil and C2 domain containing 1A
chr16_+_1584161 14.169 NM_024600
TMEM204
transmembrane protein 204
chr11_+_73358593 14.165 NM_001130034
NM_001130035
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr9_-_110251308 14.140 KLF4
Kruppel-like factor 4 (gut)
chr11_+_44587140 14.121 NM_001024844
NM_002231
CD82

CD82 molecule

chr1_+_109656507 14.116 KIAA1324
KIAA1324
chr22_-_19512859 14.116 NM_001130861
NM_003277
CLDN5

claudin 5

chr5_+_156693051 14.062 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr1_-_160990862 14.031 F11R
F11 receptor
chr10_-_21463019 14.013 NM_001173484
NM_213569
NEBL

nebulette

chr22_-_19512001 13.968 CLDN5
claudin 5
chr12_-_53448167 13.962 LOC283335
uncharacterized LOC283335
chr9_-_110251754 13.961 KLF4
Kruppel-like factor 4 (gut)
chr20_+_49348050 13.920 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr12_-_101603984 13.920 NM_145913
SLC5A8
solute carrier family 5 (iodide transporter), member 8
chr2_+_47596286 13.918 NM_002354
EPCAM
epithelial cell adhesion molecule
chr17_-_15902907 13.871 NM_001042697
NM_001042698
ZSWIM7

zinc finger, SWIM-type containing 7

chr15_+_44580870 13.759 NM_138423
NM_177974
CASC4

cancer susceptibility candidate 4

chr19_+_18794391 13.737 NM_001098482
NM_015321
CRTC1

CREB regulated transcription coactivator 1

chr16_-_74808699 13.700 NM_024306
FA2H
fatty acid 2-hydroxylase
chr2_+_17721806 13.598 NM_003385
VSNL1
visinin-like 1
chr11_+_130029699 13.541 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr14_-_24036532 13.522 AP1G2
adaptor-related protein complex 1, gamma 2 subunit
chr10_+_71211215 13.432 NM_012339
TSPAN15
tetraspanin 15
chr1_-_201368617 13.395 NM_005558
LAD1
ladinin 1
chr12_-_110434057 13.376 GIT2
G protein-coupled receptor kinase interacting ArfGAP 2
chr19_-_51537996 13.372 NM_019598
NM_145894
NM_145895
KLK12


kallikrein-related peptidase 12


chr19_-_36499583 13.330 NM_001039876
C19orf46
chromosome 19 open reading frame 46
chr12_+_7055753 13.314 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr11_-_417324 13.309 NM_001135053
NM_021805
SIGIRR

single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

chr19_+_49055421 13.276 NM_177973
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
chr2_+_17721983 13.270 VSNL1
visinin-like 1
chr4_-_16085593 13.259 NM_001145847
NM_001145848
PROM1

prominin 1

chr19_-_6279797 13.158


chr14_-_107013474 13.133 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr20_+_44098392 13.113 NM_006103
WFDC2
WAP four-disulfide core domain 2
chr16_+_68679229 13.072 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr17_-_7197811 13.028 YBX2
Y box binding protein 2
chr19_-_10341947 12.995 NM_004230
S1PR2
sphingosine-1-phosphate receptor 2
chr2_-_219925237 12.994 NM_002181
IHH
Indian hedgehog
chr15_-_48470453 12.990 NM_016132
MYEF2
myelin expression factor 2
chr17_-_39684499 12.961 KRT19
keratin 19
chr17_+_7452374 12.956 NM_172089
NM_003809
TNFSF12-TNFSF13
TNFSF12
TNFSF12-TNFSF13 readthrough
tumor necrosis factor (ligand) superfamily, member 12
chr17_-_79875995 12.884 SIRT7
sirtuin 7
chr16_-_68269948 12.869 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr4_-_36245893 12.828 NM_015230
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_-_241500167 12.772 ANKMY1
ankyrin repeat and MYND domain containing 1
chr8_+_27182995 12.746 NM_173176
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr1_+_183155361 12.744 LAMC2
laminin, gamma 2
chr22_-_50312096 12.742 NM_024105
ALG12
asparagine-linked glycosylation 12, alpha-1,6-mannosyltransferase homolog (S. cerevisiae)
chr11_-_33890931 12.731 LMO2
LIM domain only 2 (rhombotin-like 1)
chr16_+_81812899 12.697 PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr1_+_154975041 12.583 NM_001252405
NM_015872
ZBTB7B

zinc finger and BTB domain containing 7B

chr10_+_49514652 12.507 MAPK8
mitogen-activated protein kinase 8
chr7_-_97881436 12.465 NM_015395
TECPR1
tectonin beta-propeller repeat containing 1
chr19_+_18723666 12.448 NM_012109
TMEM59L
transmembrane protein 59-like
chr17_-_7197896 12.384 YBX2
Y box binding protein 2
chr16_+_68771304 12.320 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr6_+_39016556 12.306 NM_002062
GLP1R
glucagon-like peptide 1 receptor
chr6_+_110012521 12.262 FIG4
FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
chr16_-_67753186 12.237 NM_001243650
NM_030819
GFOD2

glucose-fructose oxidoreductase domain containing 2

chr14_-_107131217 12.169 IGHA1
immunoglobulin heavy constant alpha 1
chr4_+_155665150 12.159 NM_004744
LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr14_-_106111114 12.157 IGHG2
immunoglobulin heavy constant gamma 2 (G2m marker)
chr19_-_4535202 12.126 NM_001013706
PLIN5
perilipin 5
chr16_-_74808474 12.115 FA2H
fatty acid 2-hydroxylase
chr1_+_150255228 12.056 NM_144697
C1orf51
chromosome 1 open reading frame 51
chr16_+_69796237 12.041 NM_007014
NM_199423
WWP2

WW domain containing E3 ubiquitin protein ligase 2

chr15_-_45670955 11.912 NM_001482
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr22_+_38453261 11.904 NM_001039583
NM_001039584
NM_012407
PICK1


protein interacting with PRKCA 1


chr11_+_61197574 11.893 NM_017841
SDHAF2
succinate dehydrogenase complex assembly factor 2
chr2_+_155555092 11.782 NM_002239
KCNJ3
potassium inwardly-rectifying channel, subfamily J, member 3
chr1_+_29213619 11.782 EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr20_+_48599511 11.760 NM_005985
SNAI1
snail homolog 1 (Drosophila)
chr8_-_127570465 11.758 FAM84B
family with sequence similarity 84, member B
chr15_-_45670624 11.728 GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr2_+_242641310 11.641 NM_032329
ING5
inhibitor of growth family, member 5
chr14_-_106926393 11.624 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr19_+_35739838 11.622 LSR
lipolysis stimulated lipoprotein receptor
chr1_-_17445865 11.599 NM_007365
PADI2
peptidyl arginine deiminase, type II
chr19_+_35607218 11.588 FXYD3
FXYD domain containing ion transport regulator 3
chr8_-_110657025 11.584 NM_001099753
NM_001099754
NM_001099755
SYBU


syntabulin (syntaxin-interacting)


chr4_+_106473776 11.567 NM_001242729
NM_017700
ARHGEF38

Rho guanine nucleotide exchange factor (GEF) 38


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.19 9.93e-29 GO:0065007 biological regulation
1.32 2.41e-27 GO:0023052 signaling
1.12 1.54e-26 GO:0009987 cellular process
1.18 3.65e-24 GO:0050789 regulation of biological process
1.32 3.09e-22 GO:0048856 anatomical structure development
1.18 1.33e-21 GO:0050794 regulation of cellular process
1.28 2.14e-20 GO:0032502 developmental process
1.30 3.00e-20 GO:0007165 signal transduction
1.32 3.38e-19 GO:0048731 system development
1.29 3.97e-19 GO:0007275 multicellular organismal development
1.39 4.09e-16 GO:0007166 cell surface receptor linked signaling pathway
1.23 7.14e-16 GO:0051716 cellular response to stimulus
1.34 1.04e-15 GO:0042221 response to chemical stimulus
1.19 1.46e-14 GO:0032501 multicellular organismal process
1.60 1.71e-14 GO:0007267 cell-cell signaling
1.44 6.15e-14 GO:0051239 regulation of multicellular organismal process
1.16 2.46e-12 GO:0050896 response to stimulus
1.33 1.60e-11 GO:0048583 regulation of response to stimulus
1.31 3.26e-11 GO:0030154 cell differentiation
1.45 9.39e-11 GO:0007154 cell communication
1.30 1.28e-10 GO:0048869 cellular developmental process
1.31 1.33e-10 GO:0048513 organ development
1.29 2.33e-10 GO:0065008 regulation of biological quality
1.21 4.09e-10 GO:0051179 localization
1.34 4.33e-09 GO:0007399 nervous system development
1.37 5.49e-09 GO:0002376 immune system process
1.44 1.55e-08 GO:0040011 locomotion
1.30 6.11e-08 GO:0023051 regulation of signaling
1.32 8.06e-08 GO:0009653 anatomical structure morphogenesis
1.41 1.56e-07 GO:0050793 regulation of developmental process
1.45 1.98e-07 GO:0007155 cell adhesion
1.45 1.98e-07 GO:0022610 biological adhesion
1.34 2.76e-07 GO:0010033 response to organic substance
1.31 2.78e-07 GO:0065009 regulation of molecular function
1.22 3.05e-07 GO:0048518 positive regulation of biological process
1.51 6.72e-07 GO:0007186 G-protein coupled receptor protein signaling pathway
1.39 1.04e-06 GO:0006811 ion transport
1.43 1.15e-06 GO:2000026 regulation of multicellular organismal development
1.31 1.60e-06 GO:0035556 intracellular signal transduction
1.30 2.08e-06 GO:0009966 regulation of signal transduction
1.37 2.35e-06 GO:0032879 regulation of localization
1.52 3.22e-06 GO:0001775 cell activation
1.85 6.03e-06 GO:0003012 muscle system process
1.89 6.80e-06 GO:0006936 muscle contraction
1.36 8.17e-06 GO:0042127 regulation of cell proliferation
1.35 1.02e-05 GO:0009605 response to external stimulus
1.51 1.03e-05 GO:0019226 transmission of nerve impulse
1.51 1.03e-05 GO:0035637 multicellular organismal signaling
1.53 1.03e-05 GO:0051094 positive regulation of developmental process
1.19 1.09e-05 GO:0006810 transport
1.36 1.32e-05 GO:0048468 cell development
1.16 1.52e-05 GO:0019222 regulation of metabolic process
1.18 1.74e-05 GO:0051234 establishment of localization
1.37 2.39e-05 GO:0009888 tissue development
1.47 5.40e-05 GO:0006935 chemotaxis
1.47 5.40e-05 GO:0042330 taxis
1.76 5.82e-05 GO:0003013 circulatory system process
1.76 5.82e-05 GO:0008015 blood circulation
1.51 6.55e-05 GO:0007268 synaptic transmission
1.43 6.99e-05 GO:0009887 organ morphogenesis
1.30 8.90e-05 GO:0050790 regulation of catalytic activity
1.57 1.10e-04 GO:0045597 positive regulation of cell differentiation
1.44 1.26e-04 GO:0006928 cellular component movement
1.39 1.31e-04 GO:0002682 regulation of immune system process
1.35 1.60e-04 GO:0048699 generation of neurons
1.33 1.96e-04 GO:0022008 neurogenesis
1.20 2.09e-04 GO:0048519 negative regulation of biological process
1.19 2.27e-04 GO:0048522 positive regulation of cellular process
1.55 2.67e-04 GO:0044057 regulation of system process
1.15 2.73e-04 GO:0080090 regulation of primary metabolic process
1.36 2.75e-04 GO:0006955 immune response
1.38 3.09e-04 GO:0045595 regulation of cell differentiation
1.39 5.61e-04 GO:0048878 chemical homeostasis
1.37 5.95e-04 GO:0030182 neuron differentiation
1.38 6.15e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.34 6.73e-04 GO:0044093 positive regulation of molecular function
1.41 6.94e-04 GO:0006812 cation transport
1.48 8.32e-04 GO:0016477 cell migration
1.59 8.79e-04 GO:0048534 hemopoietic or lymphoid organ development
1.20 8.94e-04 GO:0048523 negative regulation of cellular process
1.56 1.07e-03 GO:0002520 immune system development
1.45 1.08e-03 GO:0048870 cell motility
1.45 1.08e-03 GO:0051674 localization of cell
1.52 1.10e-03 GO:0051240 positive regulation of multicellular organismal process
1.74 1.37e-03 GO:0071902 positive regulation of protein serine/threonine kinase activity
1.14 1.61e-03 GO:0031323 regulation of cellular metabolic process
1.42 1.91e-03 GO:0030001 metal ion transport
1.32 2.30e-03 GO:0048584 positive regulation of response to stimulus
1.48 2.37e-03 GO:0051056 regulation of small GTPase mediated signal transduction
1.89 2.41e-03 GO:0007565 female pregnancy
1.52 2.89e-03 GO:0001501 skeletal system development
1.82 2.91e-03 GO:0002521 leukocyte differentiation
1.28 3.52e-03 GO:0006793 phosphorus metabolic process
1.28 3.52e-03 GO:0006796 phosphate metabolic process
1.35 3.64e-03 GO:0009719 response to endogenous stimulus
1.53 4.21e-03 GO:0050778 positive regulation of immune response
1.37 4.37e-03 GO:0009725 response to hormone stimulus
1.34 5.10e-03 GO:0043085 positive regulation of catalytic activity
1.52 5.43e-03 GO:0045860 positive regulation of protein kinase activity
1.43 5.56e-03 GO:0002684 positive regulation of immune system process
1.51 5.68e-03 GO:0033674 positive regulation of kinase activity
1.42 6.14e-03 GO:0050776 regulation of immune response
1.17 6.97e-03 GO:0006950 response to stress
1.59 6.97e-03 GO:0008202 steroid metabolic process
1.37 7.44e-03 GO:0048666 neuron development
1.75 7.61e-03 GO:0043406 positive regulation of MAP kinase activity
1.73 7.62e-03 GO:0002237 response to molecule of bacterial origin
1.29 7.79e-03 GO:0009611 response to wounding
1.33 8.34e-03 GO:0051049 regulation of transport
1.58 8.69e-03 GO:0030168 platelet activation
1.49 8.97e-03 GO:0051347 positive regulation of transferase activity
1.32 9.35e-03 GO:0006468 protein phosphorylation
1.57 9.96e-03 GO:0030097 hemopoiesis
1.30 1.10e-02 GO:0055085 transmembrane transport
1.38 1.12e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.28 1.12e-02 GO:0070887 cellular response to chemical stimulus
1.33 1.13e-02 GO:0010628 positive regulation of gene expression
1.74 1.35e-02 GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger
1.47 1.46e-02 GO:0007411 axon guidance
1.29 1.63e-02 GO:0006952 defense response
1.40 1.83e-02 GO:0055082 cellular chemical homeostasis
1.49 2.06e-02 GO:0019932 second-messenger-mediated signaling
1.28 2.07e-02 GO:0051704 multi-organism process
1.47 2.44e-02 GO:0051093 negative regulation of developmental process
1.39 2.44e-02 GO:0050801 ion homeostasis
1.61 2.82e-02 GO:0048732 gland development
1.55 2.98e-02 GO:0002253 activation of immune response
1.40 3.12e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.72 3.19e-02 GO:0032496 response to lipopolysaccharide
1.47 3.19e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.28 3.20e-02 GO:0016310 phosphorylation
1.25 3.55e-02 GO:0010646 regulation of cell communication
1.53 3.58e-02 GO:0045321 leukocyte activation
2.40 3.67e-02 GO:0006941 striated muscle contraction
1.67 3.91e-02 GO:0019935 cyclic-nucleotide-mediated signaling
1.58 3.97e-02 GO:0043405 regulation of MAP kinase activity
1.72 4.24e-02 GO:0001503 ossification
1.48 4.63e-02 GO:0071900 regulation of protein serine/threonine kinase activity
1.39 4.71e-02 GO:0006873 cellular ion homeostasis
1.32 4.87e-02 GO:0001932 regulation of protein phosphorylation
1.39 4.87e-02 GO:0007409 axonogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.49 4.32e-35 GO:0044459 plasma membrane part
1.59 4.19e-27 GO:0005887 integral to plasma membrane
1.58 7.83e-27 GO:0031226 intrinsic to plasma membrane
1.22 5.24e-15 GO:0005886 plasma membrane
1.21 1.45e-14 GO:0071944 cell periphery
1.40 9.89e-10 GO:0044421 extracellular region part
1.43 1.66e-08 GO:0005615 extracellular space
1.40 1.54e-07 GO:0005626 insoluble fraction
1.34 1.84e-07 GO:0000267 cell fraction
1.75 4.52e-07 GO:0016323 basolateral plasma membrane
1.37 4.11e-06 GO:0005624 membrane fraction
1.22 4.46e-06 GO:0005576 extracellular region
1.42 6.88e-06 GO:0030054 cell junction
1.35 2.56e-05 GO:0031982 vesicle
1.08 1.04e-04 GO:0016020 membrane
1.33 1.58e-04 GO:0031410 cytoplasmic vesicle
1.07 2.41e-04 GO:0005737 cytoplasm
1.09 2.97e-04 GO:0044425 membrane part
1.45 4.42e-04 GO:0045202 synapse
1.78 5.64e-04 GO:0043235 receptor complex
1.32 6.82e-04 GO:0031988 membrane-bounded vesicle
1.32 1.17e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.43 2.44e-03 GO:0009986 cell surface
1.63 3.39e-03 GO:0016324 apical plasma membrane
1.24 8.48e-03 GO:0005794 Golgi apparatus
1.40 1.05e-02 GO:0031012 extracellular matrix
1.43 1.18e-02 GO:0044433 cytoplasmic vesicle part
1.45 1.87e-02 GO:0012506 vesicle membrane
1.51 1.88e-02 GO:0045177 apical part of cell
1.36 3.38e-02 GO:0043005 neuron projection
1.44 3.87e-02 GO:0030659 cytoplasmic vesicle membrane
1.50 4.49e-02 GO:0005911 cell-cell junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 1.08e-14 GO:0005515 protein binding
1.08 2.17e-14 GO:0005488 binding
1.39 5.38e-09 GO:0005102 receptor binding
1.44 1.26e-05 GO:0008324 cation transmembrane transporter activity
1.37 3.34e-05 GO:0015075 ion transmembrane transporter activity
1.28 7.39e-05 GO:0005215 transporter activity
1.78 1.17e-04 GO:0005085 guanyl-nucleotide exchange factor activity
1.30 2.14e-04 GO:0022857 transmembrane transporter activity
2.46 2.96e-04 GO:0001948 glycoprotein binding
1.84 3.20e-04 GO:0060090 binding, bridging
1.87 4.00e-04 GO:0030674 protein binding, bridging
1.31 4.14e-04 GO:0022891 substrate-specific transmembrane transporter activity
1.42 7.65e-04 GO:0030695 GTPase regulator activity
1.28 8.68e-04 GO:0022892 substrate-specific transporter activity
1.40 1.69e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.37 1.91e-03 GO:0008092 cytoskeletal protein binding
1.51 3.77e-03 GO:0005261 cation channel activity
1.64 4.06e-03 GO:0001664 G-protein-coupled receptor binding
2.60 4.45e-03 GO:0015296 anion:cation symporter activity
1.26 4.63e-03 GO:0001071 nucleic acid binding transcription factor activity
1.26 4.63e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.40 6.05e-03 GO:0022803 passive transmembrane transporter activity
1.74 6.66e-03 GO:0015276 ligand-gated ion channel activity
1.74 6.66e-03 GO:0022834 ligand-gated channel activity
1.46 8.02e-03 GO:0022836 gated channel activity
1.40 8.64e-03 GO:0015267 channel activity
1.47 8.83e-03 GO:0005083 small GTPase regulator activity
1.99 9.33e-03 GO:0005200 structural constituent of cytoskeleton
1.39 1.80e-02 GO:0022838 substrate-specific channel activity
1.24 2.36e-02 GO:0030234 enzyme regulator activity
1.27 2.66e-02 GO:0042802 identical protein binding
1.29 3.08e-02 GO:0043565 sequence-specific DNA binding
1.38 3.30e-02 GO:0005216 ion channel activity
1.83 3.47e-02 GO:0015294 solute:cation symporter activity
1.41 3.88e-02 GO:0003779 actin binding
1.29 4.15e-02 GO:0005509 calcium ion binding