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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: SOX17.p2

Z-value: 2.145

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_153643456	76.789		ILF2	interleukin enhancer binding factor 2, 45kDa
chr1_-_153643474	74.145	NM_004515	ILF2	interleukin enhancer binding factor 2, 45kDa
chr7_-_44887620	73.359		H2AFV	H2A histone family, member V
chr1_-_153643433	72.914		ILF2	interleukin enhancer binding factor 2, 45kDa
chr1_-_153643428	71.116		ILF2	interleukin enhancer binding factor 2, 45kDa
chr7_-_44887567	71.035		H2AFV	H2A histone family, member V
chr1_-_153643417	69.686		ILF2	interleukin enhancer binding factor 2, 45kDa
chr5_+_177631533	62.366		HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B
chr5_+_177631496	60.472	NM_004499 NM_031266	HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B
chr17_-_73150493	54.893		HN1	hematological and neurological expressed 1
chr5_+_177631534	52.701		HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B
chr16_+_56817367	51.279	NM_001242796	NUP93	nucleoporin 93kDa
chr5_+_68462948	47.491		CCNB1	cyclin B1
chr5_+_68462985	42.820		CCNB1	cyclin B1
chr13_-_31040035	41.519	NM_002128	HMGB1	high mobility group box 1
chr2_-_61765394	39.813	NM_003400	XPO1	exportin 1 (CRM1 homolog, yeast)
chr1_+_43824598	39.506	NM_001255	CDC20	cell division cycle 20 homolog (S. cerevisiae)
chr13_-_31039966	37.700		HMGB1	high mobility group box 1
chr5_+_68462836	33.728	NM_031966	CCNB1	cyclin B1
chr1_+_110882063	30.411		RBM15	RNA binding motif protein 15
chr1_-_26232890	30.382	NM_001145454 NM_005563	STMN1	stathmin 1
chr1_+_154947116	30.165	NM_001826	CKS1B	CDC28 protein kinase regulatory subunit 1B
chr14_+_52456322	30.055		C14orf166	chromosome 14 open reading frame 166
chr2_+_10262694	29.819	NM_001165931	RRM2	ribonucleotide reductase M2
chr2_-_61765367	29.809		XPO1	exportin 1 (CRM1 homolog, yeast)
chr1_+_154947147	29.744		CKS1B	CDC28 protein kinase regulatory subunit 1B
chr2_-_61765345	29.467		XPO1	exportin 1 (CRM1 homolog, yeast)
chr17_-_8113862	29.428	NM_004217	AURKB	aurora kinase B
chr2_+_10262853	28.953	NM_001034	RRM2	ribonucleotide reductase M2
chr17_+_26646120	28.459	NM_014573	TMEM97	transmembrane protein 97
chr3_-_52567708	28.451	NM_001134231	NT5DC2	5'-nucleotidase domain containing 2
chr16_+_56815703	28.420	NM_001242795	NUP93	nucleoporin 93kDa
chr1_+_110882057	28.379		RBM15	RNA binding motif protein 15
chr6_-_53213586	27.756		ELOVL5	ELOVL fatty acid elongase 5
chr14_+_52456192	27.721	NM_016039	C14orf166	chromosome 14 open reading frame 166
chr1_+_154947166	27.700		CKS1B	CDC28 protein kinase regulatory subunit 1B
chr6_+_30688144	27.428	NM_178014	TUBB	tubulin, beta class I
chr3_-_52567809	27.367		NT5DC2	5'-nucleotidase domain containing 2
chr1_+_110881944	26.549	NM_001201545 NM_022768	RBM15	RNA binding motif protein 15
chr19_+_13049413	26.343	NM_004343	CALR	calreticulin
chr2_+_27008881	25.716	NM_001809 NM_001042426	CENPA	centromere protein A
chr19_-_55919324	24.712	NM_014501	UBE2S	ubiquitin-conjugating enzyme E2S
chr19_+_13049428	24.321		CALR	calreticulin
chr6_+_30688085	24.148		TUBB	tubulin, beta class I
chr1_-_26233367	23.225	NM_203399	STMN1	stathmin 1
chr16_-_103557	23.136	NM_016310	POLR3K	polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
chr19_+_13049440	22.849		CALR	calreticulin
chr17_+_66031814	22.356	NM_002266	KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr7_+_12727204	22.248		ARL4A	ADP-ribosylation factor-like 4A
chr17_+_66031885	21.481		KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr6_-_79944397	20.905	NM_001201362 NM_001201363 NM_004242 NM_138730	HMGN3	high mobility group nucleosomal binding domain 3
chr20_-_5107185	20.542	NM_002592	PCNA	proliferating cell nuclear antigen
chr1_-_8931634	20.534	NM_001201483	ENO1	enolase 1, (alpha)
chr11_-_16996559	20.513		RPL36A	ribosomal protein L36a
chr1_-_197115566	20.383	NM_001206846 NM_018136	ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr3_+_51422716	20.282		MANF	mesencephalic astrocyte-derived neurotrophic factor
chr2_+_74425689	19.777	NM_006636	MTHFD2	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr20_+_44441247	19.585	NM_007019 NM_181799 NM_181800 NM_181802 NM_181803	UBE2C	ubiquitin-conjugating enzyme E2C
chr13_+_53029494	19.523	NM_001098525 NM_018204	CKAP2	cytoskeleton associated protein 2
chr14_-_64009971	19.503		PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform
chr16_+_103859	19.368		SNRNP25	small nuclear ribonucleoprotein 25kDa (U11/U12)
chr12_-_102512277	19.297	NM_024057	NUP37	nucleoporin 37kDa
chr2_+_232573226	19.119	NM_001099285 NM_002823	PTMA	prothymosin, alpha
chr12_-_6960406	19.007	NM_031299	CDCA3	cell division cycle associated 3
chr3_+_51422691	18.742	NM_006010	MANF	mesencephalic astrocyte-derived neurotrophic factor
chr15_+_59397276	18.741	NM_004701	CCNB2	cyclin B2
chr20_-_49547451	18.721	NM_015339 NM_181442	ADNP	activity-dependent neuroprotector homeobox
chr6_-_79944324	18.607		HMGN3	high mobility group nucleosomal binding domain 3
chr1_-_26232643	18.511	NM_203401	STMN1	stathmin 1
chr20_+_44441334	18.311		UBE2C	ubiquitin-conjugating enzyme E2C
chr2_+_27008912	17.945		CENPA	centromere protein A
chr9_-_128003634	17.941	NM_005347	HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr4_-_122744782	17.762		CCNA2	cyclin A2
chr4_-_122744978	17.455	NM_001237	CCNA2	cyclin A2
chr14_-_64010087	17.432		PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform
chr16_+_103892	17.409		SNRNP25	small nuclear ribonucleoprotein 25kDa (U11/U12)
chr2_+_75061234	17.380		HK2	hexokinase 2
chr6_+_27114860	17.319	NM_080596	HIST1H2AH	histone cluster 1, H2ah
chr14_-_64010063	16.909	NM_006246	PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform
chr11_-_46867840	16.744	NM_001008938 NM_014756	CKAP5	cytoskeleton associated protein 5
chr16_-_58663734	16.643		CNOT1	CCR4-NOT transcription complex, subunit 1
chr6_-_108279307	16.463		SEC63	SEC63 homolog (S. cerevisiae)
chr4_-_100871482	16.451	NM_002106	H2AFZ	H2A histone family, member Z
chr1_+_24286300	16.441	NM_017761	PNRC2	proline-rich nuclear receptor coactivator 2
chr17_+_1733263	16.336	NM_002945	RPA1	replication protein A1, 70kDa
chr12_-_31479120	16.223	NM_001135811 NM_021238 NM_001135812	FAM60A	family with sequence similarity 60, member A
chr6_-_86351156	15.917	NM_001159675 NM_001159676	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr6_+_80714321	15.893	NM_001166691 NM_003318	TTK	TTK protein kinase
chr4_-_100871431	15.736		H2AFZ	H2A histone family, member Z
chr17_-_38574042	15.541	NM_001067	TOP2A	topoisomerase (DNA) II alpha 170kDa
chr6_-_150067631	15.539	NM_198887	NUP43	nucleoporin 43kDa
chr1_-_109969058	15.335	NM_001199772 NM_002790 NM_001199773 NM_001199774	PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5
chr12_-_31479038	15.330		FAM60A	family with sequence similarity 60, member A
chr11_-_102323353	15.329	NM_052932	TMEM123	transmembrane protein 123
chr7_+_73097897	15.282	NM_001202560 NM_017528	WBSCR22	Williams Beuren syndrome chromosome region 22
chr6_+_24775640	15.251	NM_001251991	GMNN	geminin, DNA replication inhibitor
chr1_+_43148096	15.178		YBX1	Y box binding protein 1
chr9_-_128003615	15.123		HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr6_+_80714389	15.055		TTK	TTK protein kinase
chr14_+_103800534	14.944		EIF5	eukaryotic translation initiation factor 5
chr5_+_159848835	14.856	NM_004219	PTTG1	pituitary tumor-transforming 1
chr12_-_31479084	14.659		FAM60A	family with sequence similarity 60, member A
chr4_-_7069801	14.552		GRPEL1	GrpE-like 1, mitochondrial (E. coli)
chr15_-_64673569	14.419	NM_001029989 NM_014736	KIAA0101	KIAA0101
chr20_+_44441671	14.239	NM_181801	UBE2C	ubiquitin-conjugating enzyme E2C
chr17_+_1733313	14.182		RPA1	replication protein A1, 70kDa
chr14_+_23938883	14.149	NM_001042635 NM_015514	NGDN	neuroguidin, EIF4E binding protein
chr10_-_13390189	14.149	NM_001195602 NM_001195604 NM_012247	SEPHS1	selenophosphate synthetase 1
chr1_-_109969044	14.023		PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5
chr12_+_120933911	14.016		DYNLL1	dynein, light chain, LC8-type 1
chr5_+_145826866	13.966	NM_001040006 NM_006706	TCERG1	transcription elongation regulator 1
chrX_+_153991016	13.916	NM_001142463 NM_001363	DKC1	dyskeratosis congenita 1, dyskerin
chr13_+_98628712	13.807		IPO5	importin 5
chr5_+_138941323	13.651		UBE2D2	ubiquitin-conjugating enzyme E2D 2
chr7_+_16685757	13.629	NM_001159767 NM_014038	BZW2	basic leucine zipper and W2 domains 2
chr11_+_747428	13.563	NM_006755	TALDO1	transaldolase 1
chr8_+_98656494	13.537		MTDH	metadherin
chr7_-_44887697	13.495	NM_012412 NM_138635 NM_201436 NM_201516 NM_201517	H2AFV	H2A histone family, member V
chr14_+_97263681	13.469	NM_003384	VRK1	vaccinia related kinase 1
chr6_+_111135823	13.379		AMD1	adenosylmethionine decarboxylase 1
chr17_+_7476023	13.362	NM_001204510 NM_001416	EIF4A1	eukaryotic translation initiation factor 4A1
chr12_+_69979447	13.334	NM_001198842	CCT2	chaperonin containing TCP1, subunit 2 (beta)
chr19_-_8070468	13.319	NM_001419	ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
chr8_+_98656428	13.246		MTDH	metadherin
chr2_-_10952803	13.228		PDIA6	protein disulfide isomerase family A, member 6
chr2_-_174830429	13.218	NM_001172712 NM_003111	SP3	Sp3 transcription factor
chr5_+_102465256	13.198	NM_015216	PPIP5K2	diphosphoinositol pentakisphosphate kinase 2
chr15_-_59225766	13.056		SLTM	SAFB-like, transcription modulator
chr5_-_137878808	13.033		ETF1	eukaryotic translation termination factor 1
chr2_-_9770999	12.949		YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr22_+_38142255	12.889		TRIOBP	TRIO and F-actin binding protein
chr12_+_98909331	12.848	NM_001032283 NM_001032284 NM_003276	TMPO	thymopoietin
chr19_+_45394459	12.824	NM_001128916 NM_001128917 NM_006114	TOMM40	translocase of outer mitochondrial membrane 40 homolog (yeast)
chr1_+_24286311	12.743		PNRC2	proline-rich nuclear receptor coactivator 2
chr1_+_180897572	12.710
chr12_+_120933832	12.708	NM_001037495 NM_003746	DYNLL1	dynein, light chain, LC8-type 1
chr15_-_69113255	12.703	NM_006305	ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr9_+_131451519	12.665		SET	SET nuclear oncogene
chr11_+_747424	12.656		TALDO1	transaldolase 1
chr8_-_101965601	12.655	NM_003406	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr6_+_20402040	12.617	NM_001949	E2F3	E2F transcription factor 3
chr7_+_141438122	12.594	NM_003143	SSBP1	single-stranded DNA binding protein 1
chr14_+_102276125	12.503	NM_002719 NM_178586 NM_178587	PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma
chr11_+_34073188	12.430	NM_005898 NM_203364	CAPRIN1	cell cycle associated protein 1
chr2_-_10952855	12.408	NM_005742	PDIA6	protein disulfide isomerase family A, member 6
chr1_+_43148098	12.253		YBX1	Y box binding protein 1
chr5_-_137878915	12.238	NM_004730	ETF1	eukaryotic translation termination factor 1
chr9_+_131445933	12.197	NM_001122821	SET	SET nuclear oncogene
chr11_+_36317724	12.168	NM_001160167	PRR5L	proline rich 5 like
chr1_-_150208462	12.068	NM_001136478 NM_030920	ANP32E	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr6_+_114178516	12.057	NM_002356	MARCKS	myristoylated alanine-rich protein kinase C substrate
chr5_+_159848876	11.986		PTTG1	pituitary tumor-transforming 1
chr14_+_58711599	11.922		PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3
chr2_-_9771101	11.892	NM_006826	YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr9_+_131451847	11.877		SET	SET nuclear oncogene
chr15_+_66694216	11.821		MAP2K1	mitogen-activated protein kinase kinase 1
chr8_-_101965194	11.797	NM_001135699	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr12_+_123237302	11.792	NM_003677	DENR	density-regulated protein
chr14_+_103800678	11.754		EIF5	eukaryotic translation initiation factor 5
chr7_+_134464417	11.750		CALD1	caldesmon 1
chr15_+_41625052	11.742		NUSAP1	nucleolar and spindle associated protein 1
chr12_+_104324157	11.634		HSP90B1	heat shock protein 90kDa beta (Grp94), member 1
chr16_-_75529278	11.607
chr1_+_167298280	11.582	NM_001198783	POU2F1	POU class 2 homeobox 1
chr14_-_35344450	11.480		BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr14_+_20937537	11.460	NM_000270	PNP	purine nucleoside phosphorylase
chr9_-_128003348	11.401		HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr19_+_17970670	11.362	NM_000980	RPL18A	ribosomal protein L18a
chr1_+_43148048	11.349	NM_004559	YBX1	Y box binding protein 1
chr15_+_41625152	11.342		NUSAP1	nucleolar and spindle associated protein 1
chr9_+_131451470	11.338	NM_003011	SET	SET nuclear oncogene
chr12_+_56211862	11.190		ORMDL2	ORM1-like 2 (S. cerevisiae)
chr1_+_62902325	11.134	NM_003368	USP1	ubiquitin specific peptidase 1
chrX_-_151999259	11.131	NM_004344	CETN2	centrin, EF-hand protein, 2
chr10_+_22610138	11.084	NM_005180	BMI1	BMI1 polycomb ring finger oncogene
chr1_-_150208441	11.081		ANP32E	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr17_-_73150769	11.035	NM_001002032 NM_001002033 NM_016185	HN1	hematological and neurological expressed 1
chr4_-_100871418	11.025		H2AFZ	H2A histone family, member Z
chr2_-_234763182	11.012	NM_018410	HJURP	Holliday junction recognition protein
chr1_+_43148105	10.948		YBX1	Y box binding protein 1
chr1_-_151032082	10.931	NM_001038707 NM_020239	CDC42SE1	CDC42 small effector 1
chr1_-_20988023	10.896	NM_005216	DDOST	dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chr2_-_234763145	10.893		HJURP	Holliday junction recognition protein
chr11_+_747449	10.838		TALDO1	transaldolase 1
chr6_+_30689414	10.780		TUBB	tubulin, beta class I
chr10_+_94050858	10.733	NM_017824	MARCH5	membrane-associated ring finger (C3HC4) 5
chr12_+_104324192	10.669		HSP90B1	heat shock protein 90kDa beta (Grp94), member 1
chr12_-_120638894	10.655		RPLP0	ribosomal protein, large, P0
chr1_-_27816676	10.616	NM_001201404 NM_006990	WASF2	WAS protein family, member 2
chr1_-_109968951	10.607		PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5
chr1_+_155278538	10.594	NM_001135822 NM_001242824 NM_001242825 NM_002004	FDPS	farnesyl diphosphate synthase
chr5_+_154092461	10.567	NM_015315	LARP1	La ribonucleoprotein domain family, member 1
chr15_-_69113213	10.556		ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr3_-_57583080	10.539		ARF4	ADP-ribosylation factor 4
chr6_-_53213699	10.489		ELOVL5	ELOVL fatty acid elongase 5
chr1_-_33815340	10.464		PHC2	polyhomeotic homolog 2 (Drosophila)
chr1_+_43148142	10.386		YBX1	Y box binding protein 1
chr1_+_155278727	10.350		FDPS	farnesyl diphosphate synthase
chr8_-_109260940	10.309	NM_001568	EIF3E	eukaryotic translation initiation factor 3, subunit E
chr14_+_102276279	10.281		PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.25	1.99e-32	GO:0009987	cellular process
1.61	4.00e-29	GO:0044260	cellular macromolecule metabolic process
1.45	4.45e-28	GO:0044237	cellular metabolic process
1.89	6.79e-25	GO:0090304	nucleic acid metabolic process
1.77	1.31e-24	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.68	3.56e-23	GO:0034641	cellular nitrogen compound metabolic process
1.66	3.90e-23	GO:0006807	nitrogen compound metabolic process
1.40	3.55e-22	GO:0044238	primary metabolic process
1.48	1.54e-21	GO:0043170	macromolecule metabolic process
1.35	2.96e-21	GO:0008152	metabolic process
1.93	3.88e-20	GO:0016070	RNA metabolic process
1.60	9.83e-15	GO:0071841	cellular component organization or biogenesis at cellular level
1.76	1.51e-14	GO:0010467	gene expression
1.51	2.63e-14	GO:0071840	cellular component organization or biogenesis
1.82	2.69e-14	GO:0006996	organelle organization
1.60	6.40e-14	GO:0071842	cellular component organization at cellular level
1.51	8.91e-14	GO:0016043	cellular component organization
2.41	7.80e-13	GO:0000278	mitotic cell cycle
1.73	8.34e-12	GO:0009059	macromolecule biosynthetic process
2.41	9.68e-12	GO:0016071	mRNA metabolic process
1.73	9.69e-12	GO:0034645	cellular macromolecule biosynthetic process
1.57	5.93e-11	GO:0044249	cellular biosynthetic process
1.92	2.79e-10	GO:0007049	cell cycle
1.54	3.22e-10	GO:0009058	biosynthetic process
2.15	3.34e-10	GO:0022403	cell cycle phase
2.79	6.81e-10	GO:0051329	interphase of mitotic cell cycle
2.02	1.01e-09	GO:0022402	cell cycle process
2.74	1.53e-09	GO:0051325	interphase
1.24	3.25e-09	GO:0050789	regulation of biological process
1.25	4.73e-09	GO:0050794	regulation of cellular process
1.54	2.91e-08	GO:0048523	negative regulation of cellular process
2.07	5.05e-08	GO:0006396	RNA processing
1.40	5.53e-08	GO:0060255	regulation of macromolecule metabolic process
1.21	6.61e-08	GO:0065007	biological regulation
2.08	6.70e-08	GO:0051276	chromosome organization
1.49	7.36e-08	GO:0048522	positive regulation of cellular process
1.74	8.26e-08	GO:0044085	cellular component biogenesis
1.47	2.25e-07	GO:0044267	cellular protein metabolic process
1.48	2.61e-07	GO:0048519	negative regulation of biological process
2.53	3.67e-07	GO:0008380	RNA splicing
2.03	3.74e-07	GO:0051726	regulation of cell cycle
2.19	5.62e-07	GO:0006325	chromatin organization
2.15	7.39e-07	GO:0034621	cellular macromolecular complex subunit organization
1.81	8.16e-07	GO:0010605	negative regulation of macromolecule metabolic process
2.39	8.84e-07	GO:0010564	regulation of cell cycle process
1.43	1.15e-06	GO:0048518	positive regulation of biological process
1.44	1.22e-06	GO:0010468	regulation of gene expression
1.70	1.75e-06	GO:0010604	positive regulation of macromolecule metabolic process
2.33	1.78e-06	GO:0034622	cellular macromolecular complex assembly
1.76	2.55e-06	GO:0032774	RNA biosynthetic process
1.75	2.75e-06	GO:0009892	negative regulation of metabolic process
1.35	2.93e-06	GO:0031323	regulation of cellular metabolic process
1.67	3.23e-06	GO:0031325	positive regulation of cellular metabolic process
1.72	3.45e-06	GO:0022607	cellular component assembly
1.81	4.56e-06	GO:0043933	macromolecular complex subunit organization
2.78	4.86e-06	GO:0000375	RNA splicing, via transesterification reactions
1.32	6.73e-06	GO:0019222	regulation of metabolic process
1.86	6.96e-06	GO:0071844	cellular component assembly at cellular level
1.97	7.28e-06	GO:0010629	negative regulation of gene expression
2.23	7.56e-06	GO:0006397	mRNA processing
1.88	1.08e-05	GO:0065003	macromolecular complex assembly
1.82	1.20e-05	GO:0046907	intracellular transport
1.77	1.20e-05	GO:0006351	transcription, DNA-dependent
1.63	1.21e-05	GO:0009893	positive regulation of metabolic process
1.44	1.59e-05	GO:0051252	regulation of RNA metabolic process
1.33	1.69e-05	GO:0080090	regulation of primary metabolic process
1.61	1.91e-05	GO:0051641	cellular localization
1.66	2.40e-05	GO:0051649	establishment of localization in cell
2.71	2.43e-05	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.71	2.43e-05	GO:0000398	nuclear mRNA splicing, via spliceosome
1.72	5.35e-05	GO:0031324	negative regulation of cellular metabolic process
2.06	8.49e-05	GO:0000279	M phase
1.75	9.36e-05	GO:0051128	regulation of cellular component organization
1.40	1.15e-04	GO:2000112	regulation of cellular macromolecule biosynthetic process
3.10	1.51e-04	GO:0050657	nucleic acid transport
3.10	1.51e-04	GO:0050658	RNA transport
3.10	1.51e-04	GO:0051236	establishment of RNA localization
1.38	1.88e-04	GO:0010556	regulation of macromolecule biosynthetic process
1.92	2.22e-04	GO:0044265	cellular macromolecule catabolic process
2.46	2.50e-04	GO:0071156	regulation of cell cycle arrest
2.50	2.51e-04	GO:0000075	cell cycle checkpoint
1.91	2.62e-04	GO:0045892	negative regulation of transcription, DNA-dependent
1.90	2.76e-04	GO:0051253	negative regulation of RNA metabolic process
3.00	3.22e-04	GO:0006403	RNA localization
1.83	3.35e-04	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
2.23	3.39e-04	GO:0000087	M phase of mitotic cell cycle
1.35	4.66e-04	GO:0051171	regulation of nitrogen compound metabolic process
2.82	4.93e-04	GO:0000082	G1/S transition of mitotic cell cycle
2.61	5.40e-04	GO:0006913	nucleocytoplasmic transport
1.79	5.48e-04	GO:0010558	negative regulation of macromolecule biosynthetic process
2.48	6.48e-04	GO:0006605	protein targeting
2.58	7.23e-04	GO:0051169	nuclear transport
2.20	9.28e-04	GO:0000280	nuclear division
2.20	9.28e-04	GO:0007067	mitosis
2.18	9.65e-04	GO:0048285	organelle fission
2.07	9.81e-04	GO:0044419	interspecies interaction between organisms
2.06	1.08e-03	GO:0016568	chromatin modification
1.26	1.19e-03	GO:0051716	cellular response to stimulus
3.02	1.27e-03	GO:0051028	mRNA transport
1.34	1.34e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.70	1.52e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38	1.54e-03	GO:0006355	regulation of transcription, DNA-dependent
1.74	1.58e-03	GO:0031327	negative regulation of cellular biosynthetic process
2.63	1.59e-03	GO:0010498	proteasomal protein catabolic process
2.63	1.59e-03	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
2.22	1.75e-03	GO:0007346	regulation of mitotic cell cycle
1.73	1.94e-03	GO:0009890	negative regulation of biosynthetic process
1.65	2.40e-03	GO:0033554	cellular response to stress
3.39	2.52e-03	GO:0006839	mitochondrial transport
1.69	2.52e-03	GO:0010557	positive regulation of macromolecule biosynthetic process
1.51	2.53e-03	GO:0010033	response to organic substance
1.67	3.00e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
2.93	3.92e-03	GO:0000086	G2/M transition of mitotic cell cycle
2.67	4.00e-03	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
1.75	4.05e-03	GO:0009057	macromolecule catabolic process
2.90	4.68e-03	GO:0000084	S phase of mitotic cell cycle
1.71	5.07e-03	GO:0051254	positive regulation of RNA metabolic process
1.62	5.48e-03	GO:0031328	positive regulation of cellular biosynthetic process
2.74	5.66e-03	GO:0007093	mitotic cell cycle checkpoint
1.30	5.68e-03	GO:0019538	protein metabolic process
1.76	5.87e-03	GO:0006259	DNA metabolic process
1.32	6.12e-03	GO:0031326	regulation of cellular biosynthetic process
2.56	6.43e-03	GO:0071103	DNA conformation change
2.85	6.61e-03	GO:0051320	S phase
1.40	7.36e-03	GO:0006464	protein modification process
2.12	8.23e-03	GO:0010608	posttranscriptional regulation of gene expression
2.04	8.54e-03	GO:0006511	ubiquitin-dependent protein catabolic process
1.72	8.92e-03	GO:0045893	positive regulation of transcription, DNA-dependent
1.72	9.47e-03	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.86	9.90e-03	GO:0090068	positive regulation of cell cycle process
1.38	1.08e-02	GO:0043412	macromolecule modification
2.41	1.10e-02	GO:0016570	histone modification
1.60	1.13e-02	GO:0009891	positive regulation of biosynthetic process
2.83	1.17e-02	GO:0065004	protein-DNA complex assembly
1.96	1.30e-02	GO:0051301	cell division
1.55	1.33e-02	GO:0042127	regulation of cell proliferation
1.67	1.39e-02	GO:0010628	positive regulation of gene expression
1.31	1.42e-02	GO:0009889	regulation of biosynthetic process
2.00	1.48e-02	GO:0019941	modification-dependent protein catabolic process
1.70	1.49e-02	GO:0051172	negative regulation of nitrogen compound metabolic process
2.37	1.60e-02	GO:0016569	covalent chromatin modification
1.98	1.77e-02	GO:0043632	modification-dependent macromolecule catabolic process
1.49	1.83e-02	GO:0044248	cellular catabolic process
1.76	2.52e-02	GO:0034613	cellular protein localization
1.53	2.67e-02	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.95	2.99e-02	GO:0051603	proteolysis involved in cellular protein catabolic process
1.74	3.08e-02	GO:0070727	cellular macromolecule localization
2.68	3.09e-02	GO:0071824	protein-DNA complex subunit organization
2.24	3.94e-02	GO:0022613	ribonucleoprotein complex biogenesis
2.19	4.60e-02	GO:0071843	cellular component biogenesis at cellular level
2.84	4.71e-02	GO:0006334	nucleosome assembly
2.61	4.86e-02	GO:0017038	protein import
1.91	4.94e-02	GO:0044257	cellular protein catabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.26	9.06e-38	GO:0044424	intracellular part
1.24	2.01e-35	GO:0005622	intracellular
1.53	3.88e-34	GO:0005634	nucleus
1.30	7.30e-33	GO:0043229	intracellular organelle
1.30	8.16e-33	GO:0043226	organelle
1.33	7.99e-31	GO:0043227	membrane-bounded organelle
1.33	1.01e-30	GO:0043231	intracellular membrane-bounded organelle
1.92	8.11e-28	GO:0044428	nuclear part
1.87	4.02e-27	GO:0031974	membrane-enclosed lumen
1.87	5.97e-27	GO:0043233	organelle lumen
1.87	6.06e-26	GO:0070013	intracellular organelle lumen
1.96	1.37e-24	GO:0031981	nuclear lumen
1.45	5.74e-24	GO:0044446	intracellular organelle part
1.44	2.48e-23	GO:0044422	organelle part
2.10	6.77e-22	GO:0005654	nucleoplasm
1.54	2.65e-18	GO:0032991	macromolecular complex
1.27	7.31e-18	GO:0005737	cytoplasm
1.46	4.06e-10	GO:0043234	protein complex
2.04	4.62e-10	GO:0044451	nucleoplasm part
1.56	7.24e-10	GO:0005829	cytosol
1.42	1.18e-07	GO:0043228	non-membrane-bounded organelle
1.42	1.18e-07	GO:0043232	intracellular non-membrane-bounded organelle
1.24	1.85e-07	GO:0044444	cytoplasmic part
2.68	4.13e-07	GO:0016604	nuclear body
2.06	4.71e-07	GO:0030529	ribonucleoprotein complex
1.06	1.03e-06	GO:0044464	cell part
1.06	1.07e-06	GO:0005623	cell
1.97	2.19e-06	GO:0005694	chromosome
1.80	1.15e-05	GO:0031967	organelle envelope
1.79	1.36e-05	GO:0031975	envelope
1.99	2.03e-05	GO:0044427	chromosomal part
7.26	7.63e-05	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
2.27	3.90e-04	GO:0000785	chromatin
3.41	1.37e-03	GO:0005643	nuclear pore
4.79	3.28e-03	GO:0000932	cytoplasmic mRNA processing body
2.99	5.83e-03	GO:0046930	pore complex
3.50	6.36e-03	GO:0016605	PML body
2.00	2.38e-02	GO:0005635	nuclear envelope
2.64	2.42e-02	GO:0005788	endoplasmic reticulum lumen
2.05	2.89e-02	GO:0000228	nuclear chromosome
1.69	3.10e-02	GO:0005740	mitochondrial envelope
3.56	3.74e-02	GO:0017053	transcriptional repressor complex
2.61	4.24e-02	GO:0032993	protein-DNA complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.49	1.05e-45	GO:0005515	protein binding
1.21	2.13e-27	GO:0005488	binding
1.48	3.79e-13	GO:0003676	nucleic acid binding
2.08	1.75e-12	GO:0003723	RNA binding
1.67	6.63e-06	GO:0030528	transcription regulator activity
1.40	1.67e-05	GO:0003677	DNA binding
1.40	3.10e-05	GO:0000166	nucleotide binding
2.13	2.52e-04	GO:0016564	transcription repressor activity
2.01	2.91e-04	GO:0003712	transcription cofactor activity
2.00	3.18e-04	GO:0000988	protein binding transcription factor activity
2.00	3.18e-04	GO:0000989	transcription factor binding transcription factor activity
2.06	2.10e-03	GO:0008134	transcription factor binding
2.43	9.31e-03	GO:0003714	transcription corepressor activity
1.49	1.46e-02	GO:0001071	nucleic acid binding transcription factor activity
1.49	1.46e-02	GO:0003700	sequence-specific DNA binding transcription factor activity
1.55	2.70e-02	GO:0019899	enzyme binding
2.88	3.94e-02	GO:0003729	mRNA binding