Motif ID: SOX2.p2

Z-value: 1.852


Transcription factors associated with SOX2.p2:

Gene SymbolEntrez IDGene Name
SOX2 6657 SRY (sex determining region Y)-box 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX2chr3_+_1814300750.307.5e-06Click!


Activity profile for motif SOX2.p2.

activity profile for motif SOX2.p2


Sorted Z-values histogram for motif SOX2.p2

Sorted Z-values for motif SOX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_84647342 38.977 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr20_+_11898536 38.923 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr4_-_176733413 36.198 GPM6A
glycoprotein M6A
chr3_+_39509069 32.924 NM_182935
MOBP
myelin-associated oligodendrocyte basic protein
chr2_+_102508333 30.470 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr1_-_32801606 29.340 NM_023009
MARCKSL1
MARCKS-like 1
chr2_-_2334887 26.738 NM_015025
MYT1L
myelin transcription factor 1-like
chr7_+_26400503 25.897 NM_001199837
SNX10
sorting nexin 10
chrX_+_123234462 25.820 STAG2
stromal antigen 2
chr1_-_26233367 23.670 NM_203399
STMN1
stathmin 1
chr15_+_52311408 23.243 NM_002748
MAPK6
mitogen-activated protein kinase 6
chr2_+_102508377 23.123 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr12_-_45307710 20.796 NM_001145110
NELL2
NEL-like 2 (chicken)
chr4_+_166131170 20.462 NM_001161521
NM_001161522
KLHL2

kelch-like 2, Mayven (Drosophila)

chr15_+_52311438 20.187 MAPK6
mitogen-activated protein kinase 6
chr15_+_52311432 20.038 MAPK6
mitogen-activated protein kinase 6
chr4_+_41258941 19.787 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr7_+_94297448 19.575 PEG10
paternally expressed 10
chr4_-_176733901 19.505 GPM6A
glycoprotein M6A
chr1_+_50571963 19.158 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr16_+_89989686 18.631 NM_006086
TUBB3
tubulin, beta 3 class III
chr6_+_123100645 18.158 NM_001446
FABP7
fatty acid binding protein 7, brain
chr14_-_60097223 17.994 RTN1
reticulon 1
chr3_-_58563490 17.471 NM_001076778
NM_007177
FAM107A

family with sequence similarity 107, member A

chr6_+_114178516 17.373 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr2_-_55199894 17.008


chr1_+_87797371 16.723 LMO4
LIM domain only 4
chr9_-_86584079 16.707 HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr7_+_149570004 16.697 NM_001100592
NM_145230
ATP6V0E2

ATPase, H+ transporting V0 subunit e2

chr3_-_58563070 16.599 FAM107A
family with sequence similarity 107, member A
chr1_+_151032866 16.348 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr12_-_16759531 16.178 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr18_-_74728963 16.161 MBP
myelin basic protein
chr1_+_151032880 16.148 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr18_-_74729049 16.088 NM_001025081
NM_001025090
NM_001025092
NM_002385
MBP



myelin basic protein



chr4_+_41258909 15.942 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr4_+_41258895 15.836 NM_004181
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr17_-_1248346 15.827 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr15_+_80364902 15.303 NM_001242915
NM_001242916
ZFAND6

zinc finger, AN1-type domain 6

chr12_-_16759430 15.245 LMO3
LIM domain only 3 (rhombotin-like 2)
chr7_-_111846384 15.170 NM_014705
DOCK4
dedicator of cytokinesis 4
chr17_-_42992852 15.147 NM_001131019
NM_001242376
NM_002055
GFAP


glial fibrillary acidic protein


chr1_+_151032683 15.130 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_-_85930610 15.098 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr4_-_83347222 14.852 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr19_-_6502224 14.795 NM_006087
TUBB4A
tubulin, beta 4A class IVa
chr16_+_89988416 14.692 NM_001197181
TUBB3
tubulin, beta 3 class III
chr8_+_80523351 14.556 STMN2
stathmin-like 2
chr12_-_16757944 14.540 LMO3
LIM domain only 3 (rhombotin-like 2)
chr16_+_58534045 14.486 NM_001242833
NM_001242834
NM_001242835
NM_001242836
NDRG4



NDRG family member 4



chr2_+_181845605 14.455 UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr2_-_26205437 14.232 NM_002254
KIF3C
kinesin family member 3C
chr2_-_26205327 13.745 KIF3C
kinesin family member 3C
chr8_+_80523048 13.715 NM_001199214
NM_007029
STMN2

stathmin-like 2

chr1_-_95392501 13.431 NM_001839
CNN3
calponin 3, acidic
chr5_+_140213968 13.369 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr8_+_80523376 13.324 STMN2
stathmin-like 2
chr12_+_120933911 13.315 DYNLL1
dynein, light chain, LC8-type 1
chr5_+_36606667 13.157 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_83876769 13.072 HDGFRP3
hepatoma-derived growth factor, related protein 3
chrX_+_80457302 13.065 NM_003022
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr14_-_60097314 13.050 RTN1
reticulon 1
chr1_-_86043932 12.956 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr6_+_121756744 12.837 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chrX_-_13835187 12.795 GPM6B
glycoprotein M6B
chr5_+_36606456 12.771 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr2_+_181845803 12.761 UBE2E3
ubiquitin-conjugating enzyme E2E 3
chrX_-_13835012 12.608 GPM6B
glycoprotein M6B
chr12_-_118498893 12.582 NM_018639
WSB2
WD repeat and SOCS box containing 2
chr8_+_80523304 12.486 STMN2
stathmin-like 2
chr3_+_238274 12.461 NM_001253387
NM_006614
CHL1

cell adhesion molecule with homology to L1CAM (close homolog of L1)

chr5_+_140739589 12.186 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr8_+_80523339 12.130 STMN2
stathmin-like 2
chr9_+_71819926 12.055 NM_001170415
NM_001170416
TJP2

tight junction protein 2 (zona occludens 2)

chr1_+_155853546 11.953 SYT11
synaptotagmin XI
chr12_-_49582800 11.930 NM_006009
TUBA1A
tubulin, alpha 1a
chr2_+_149633173 11.913


chr1_-_51887740 11.827 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr1_+_50574601 11.738 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr17_-_37764165 11.702 NM_006160
NEUROD2
neurogenic differentiation 2
chr5_+_140254930 11.686 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr1_+_50574589 11.580 NM_001144774
NM_021952
ELAVL4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

chr4_-_74088773 11.572 ANKRD17
ankyrin repeat domain 17
chr2_-_200325200 11.541 SATB2
SATB homeobox 2
chr5_+_140186658 11.525 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr6_-_128841432 11.396 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr12_+_120933832 11.385 NM_001037495
NM_003746
DYNLL1

dynein, light chain, LC8-type 1

chr16_+_58497548 11.361 NM_020465
NDRG4
NDRG family member 4
chr10_+_11207053 11.242 CELF2
CUGBP, Elav-like family member 2
chr16_+_58497628 11.236 NDRG4
NDRG family member 4
chr8_-_80993009 11.235 NM_001025252
TPD52
tumor protein D52
chr6_-_46293404 10.997 RCAN2
regulator of calcineurin 2
chrX_-_13835313 10.915 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr2_+_169312793 10.848 NM_203463
CERS6
ceramide synthase 6
chr6_+_119215240 10.612 NM_014034
ASF1A
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chrX_+_100333835 10.517 NM_021637
TMEM35
transmembrane protein 35
chrX_-_138287180 10.485 NM_001139498
NM_001139500
NM_001139501
FGF13


fibroblast growth factor 13


chr1_-_95392449 10.476 CNN3
calponin 3, acidic
chr8_-_102803178 10.334 NCALD
neurocalcin delta
chrX_+_80457597 10.321 SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chrX_-_13835213 10.293 GPM6B
glycoprotein M6B
chr1_-_156217717 10.282 NM_198406
NM_024897
PAQR6

progestin and adipoQ receptor family member VI

chr4_+_158141735 10.222 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr2_-_225370687 10.208 CUL3
cullin 3
chr4_-_87028805 10.198 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr8_-_102803196 10.194 NCALD
neurocalcin delta
chr11_-_123524881 10.041 SCN3B
sodium channel, voltage-gated, type III, beta
chr14_-_60097531 10.030 NM_206852
RTN1
reticulon 1
chr6_+_123100860 9.996 FABP7
fatty acid binding protein 7, brain
chr5_-_88199868 9.964 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr7_+_154002194 9.860 NM_001936
DPP6
dipeptidyl-peptidase 6
chr6_+_30688085 9.752 TUBB
tubulin, beta class I
chr11_-_117747331 9.722 FXYD6
FXYD domain containing ion transport regulator 6
chr17_-_29624249 9.627 NM_002544
OMG
oligodendrocyte myelin glycoprotein
chr15_-_64995346 9.616 OAZ2
ornithine decarboxylase antizyme 2
chr15_+_91643181 9.587 NM_001167580
SV2B
synaptic vesicle glycoprotein 2B
chr8_-_18666295 9.571 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr12_+_49212253 9.554 NM_000725
NM_001206915
CACNB3

calcium channel, voltage-dependent, beta 3 subunit

chr4_-_176734181 9.523 NM_201591
GPM6A
glycoprotein M6A
chr1_-_149900143 9.505 NM_005850
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr15_+_84115979 9.474 NM_003027
SH3GL3
SH3-domain GRB2-like 3
chr10_+_11206928 9.412 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr22_-_50523853 9.408 MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr1_+_87794576 9.388 LMO4
LIM domain only 4
chr12_-_16758839 9.287 NM_001243612
LMO3
LIM domain only 3 (rhombotin-like 2)
chr5_-_32388687 9.152 ZFR
zinc finger RNA binding protein
chr13_-_24007822 9.103 NM_014363
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr1_+_244216506 9.086 NM_006352
ZNF238
zinc finger protein 238
chr5_+_71502700 9.039 MAP1B
microtubule-associated protein 1B
chr8_+_26435920 9.014 NM_001244604
DPYSL2
dihydropyrimidinase-like 2
chr2_+_102314162 8.971 NM_001242560
NM_004834
NM_145686
NM_001242559
NM_145687
MAP4K4




mitogen-activated protein kinase kinase kinase kinase 4




chr13_-_53422773 8.945 NM_002590
NM_032949
PCDH8

protocadherin 8

chr12_+_69979447 8.841 NM_001198842
CCT2
chaperonin containing TCP1, subunit 2 (beta)
chr1_+_163038564 8.840 NM_005613
RGS4
regulator of G-protein signaling 4
chr5_+_36608430 8.819 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_+_163038934 8.791 NM_001113381
RGS4
regulator of G-protein signaling 4
chr5_-_111091947 8.791 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr21_-_32931289 8.783 NM_003253
TIAM1
T-cell lymphoma invasion and metastasis 1
chr4_-_87281374 8.540 NM_138980
NM_138982
MAPK10

mitogen-activated protein kinase 10

chr5_+_140749830 8.522 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chr2_-_55277592 8.509 RTN4
reticulon 4
chr19_-_42806460 8.444 NM_002573
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr4_+_41614911 8.425 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr11_-_10830581 8.383 NM_001042559
NM_001418
EIF4G2

eukaryotic translation initiation factor 4 gamma, 2

chr19_-_42806928 8.368 NM_001145939
NM_001145940
PAFAH1B3

platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)

chr12_+_120933916 8.344 DYNLL1
dynein, light chain, LC8-type 1
chr5_+_137673223 8.313 NM_001135647
FAM53C
family with sequence similarity 53, member C
chr2_+_10262853 8.312 NM_001034
RRM2
ribonucleotide reductase M2
chr2_-_55277421 8.294 RTN4
reticulon 4
chr4_-_83347778 8.218 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr5_-_146435589 8.187 NM_181674
NM_181676
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr1_+_244214576 8.180 ZNF238
zinc finger protein 238
chr4_-_83350548 8.178 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr2_-_74601653 8.175 NM_001135041
NM_023019
DCTN1

dynactin 1

chr5_+_65372744 8.140 ERBB2IP
erbb2 interacting protein
chr15_+_57210972 8.130 TCF12
transcription factor 12
chrX_+_51927918 8.005 NM_001098800
NM_001242362
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B



melanoma antigen family D, 4
melanoma antigen family D, 4B



chr2_-_55277672 7.937 RTN4
reticulon 4
chr18_-_21852189 7.935 NM_018030
OSBPL1A
oxysterol binding protein-like 1A
chr5_-_11903964 7.926 NM_001332
CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr5_-_32388595 7.898 ZFR
zinc finger RNA binding protein
chr2_+_10262694 7.891 NM_001165931
RRM2
ribonucleotide reductase M2
chr15_+_65822842 7.883 PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr1_-_110283659 7.873 NM_000849
GSTM3
glutathione S-transferase mu 3 (brain)
chr2_-_55277620 7.822 RTN4
reticulon 4
chr2_-_55277653 7.813 RTN4
reticulon 4
chr21_+_18885104 7.782 NM_001207063
NM_001207064
NM_001207065
NM_001207066
NM_001338
CXADR




coxsackie virus and adenovirus receptor




chr5_+_140797243 7.771 NM_018927
PCDHGB7
protocadherin gamma subfamily B, 7
chr4_+_113970784 7.712 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr7_-_47621635 7.709 TNS3
tensin 3
chr5_-_16936371 7.676 NM_012334
MYO10
myosin X
chr15_+_22892683 7.674 NM_014608
CYFIP1
cytoplasmic FMR1 interacting protein 1
chr11_-_72380107 7.664 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr5_+_65222381 7.615 NM_001006600
NM_001253697
NM_001253698
NM_001253699
NM_001253701
NM_018695
ERBB2IP





erbb2 interacting protein





chrX_-_51812249 7.586 NM_001098800
NM_001242362
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B



melanoma antigen family D, 4
melanoma antigen family D, 4B



chr11_-_117166247 7.558 NM_001207048
NM_001207049
BACE1

beta-site APP-cleaving enzyme 1

chr2_-_175869910 7.543 NM_001822
NM_001025201
CHN1

chimerin (chimaerin) 1

chr2_+_62934030 7.524 NM_001142614
EHBP1
EH domain binding protein 1
chr6_+_30688144 7.515 NM_178014
TUBB
tubulin, beta class I
chr4_-_76598289 7.484 NM_012297
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr5_+_140797270 7.473 PCDHGB7
protocadherin gamma subfamily B, 7
chr2_-_55277698 7.469 NM_020532
NM_153828
NM_207520
RTN4


reticulon 4


chr18_+_29171729 7.442 NM_000371
TTR
transthyretin
chr5_-_146460991 7.437 NM_181677
NM_181678
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr11_-_10830452 7.371 EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr2_-_55277459 7.342 RTN4
reticulon 4
chr6_-_75965845 7.320 TMEM30A
transmembrane protein 30A
chr6_-_79944397 7.314 NM_001201362
NM_001201363
NM_004242
NM_138730
HMGN3



high mobility group nucleosomal binding domain 3



chr6_-_79944324 7.253 HMGN3
high mobility group nucleosomal binding domain 3
chr3_+_159557745 7.238 SCHIP1
schwannomin interacting protein 1
chr10_-_62332666 7.220 NM_001204404
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr15_+_22892714 7.189 CYFIP1
cytoplasmic FMR1 interacting protein 1
chr7_-_47621741 7.187 NM_022748
TNS3
tensin 3
chr1_-_177133950 7.141 NM_004319
NM_207108
ASTN1

astrotactin 1

chr12_-_45270071 7.140 NELL2
NEL-like 2 (chicken)
chr2_-_166060552 7.136 NM_001081676
NM_001081677
NM_006922
SCN3A


sodium channel, voltage-gated, type III, alpha subunit


chr15_+_22892699 7.126 CYFIP1
cytoplasmic FMR1 interacting protein 1
chr16_+_6069094 7.113 NM_001142333
NM_018723
RBFOX1

RNA binding protein, fox-1 homolog (C. elegans) 1

chr22_-_50523737 7.103 MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr15_+_22892723 7.095 CYFIP1
cytoplasmic FMR1 interacting protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.22 1.58e-25 GO:0009987 cellular process
1.96 1.89e-19 GO:0007399 nervous system development
1.47 4.49e-13 GO:0071840 cellular component organization or biogenesis
1.55 4.66e-13 GO:0071841 cellular component organization or biogenesis at cellular level
1.56 5.89e-13 GO:0071842 cellular component organization at cellular level
1.47 1.71e-12 GO:0016043 cellular component organization
1.46 3.71e-09 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.40 4.43e-09 GO:0007275 multicellular organismal development
1.45 4.98e-09 GO:0048731 system development
1.41 8.00e-09 GO:0034641 cellular nitrogen compound metabolic process
1.40 1.44e-08 GO:0006807 nitrogen compound metabolic process
1.40 2.99e-08 GO:0048856 anatomical structure development
1.35 1.37e-07 GO:0032502 developmental process
1.84 1.53e-07 GO:0048699 generation of neurons
3.31 2.17e-07 GO:0007156 homophilic cell adhesion
1.58 2.18e-07 GO:0006996 organelle organization
1.78 7.71e-07 GO:0022008 neurogenesis
6.03 2.21e-06 GO:0007416 synapse assembly
1.79 3.45e-06 GO:0051128 regulation of cellular component organization
1.20 3.47e-06 GO:0050794 regulation of cellular process
1.18 6.39e-06 GO:0065007 biological regulation
1.43 1.74e-05 GO:0090304 nucleic acid metabolic process
1.66 1.89e-05 GO:0007049 cell cycle
1.21 3.92e-05 GO:0044237 cellular metabolic process
1.96 5.11e-05 GO:0031175 neuron projection development
2.85 5.16e-05 GO:0031344 regulation of cell projection organization
2.02 5.20e-05 GO:0048812 neuron projection morphogenesis
1.88 6.20e-05 GO:0048666 neuron development
2.04 7.82e-05 GO:0007409 axonogenesis
1.79 9.04e-05 GO:0022403 cell cycle phase
1.72 9.64e-05 GO:0022402 cell cycle process
1.29 1.14e-04 GO:0023052 signaling
1.94 1.14e-04 GO:0019226 transmission of nerve impulse
1.94 1.14e-04 GO:0035637 multicellular organismal signaling
1.99 1.37e-04 GO:0007268 synaptic transmission
1.99 1.37e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
2.05 1.48e-04 GO:0006397 mRNA processing
1.77 1.55e-04 GO:0030182 neuron differentiation
1.88 1.85e-04 GO:0016071 mRNA metabolic process
1.17 2.00e-04 GO:0050789 regulation of biological process
1.44 2.01e-04 GO:0010467 gene expression
1.83 2.36e-04 GO:0000278 mitotic cell cycle
4.17 2.47e-04 GO:0050808 synapse organization
1.66 2.85e-04 GO:0008219 cell death
1.45 3.17e-04 GO:0016070 RNA metabolic process
2.91 3.28e-04 GO:0010975 regulation of neuron projection development
1.89 3.35e-04 GO:0032990 cell part morphogenesis
1.71 3.60e-04 GO:0071844 cellular component assembly at cellular level
1.65 3.71e-04 GO:0016265 death
1.89 3.89e-04 GO:0000904 cell morphogenesis involved in differentiation
2.16 4.77e-04 GO:0016337 cell-cell adhesion
1.88 5.05e-04 GO:0048858 cell projection morphogenesis
1.62 7.75e-04 GO:0048468 cell development
1.76 7.79e-04 GO:0032989 cellular component morphogenesis
1.77 1.33e-03 GO:0000902 cell morphogenesis
1.74 1.41e-03 GO:0030030 cell projection organization
1.24 1.47e-03 GO:0044260 cellular macromolecule metabolic process
1.38 2.00e-03 GO:0030154 cell differentiation
2.78 2.37e-03 GO:0010638 positive regulation of organelle organization
2.04 2.38e-03 GO:0033043 regulation of organelle organization
1.27 2.39e-03 GO:0051179 localization
1.36 2.41e-03 GO:0048523 negative regulation of cellular process
1.81 2.62e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.36 2.86e-03 GO:0048869 cellular developmental process
5.53 3.12e-03 GO:0016339 calcium-dependent cell-cell adhesion
2.06 3.54e-03 GO:0051329 interphase of mitotic cell cycle
2.22 3.81e-03 GO:0051129 negative regulation of cellular component organization
1.16 4.02e-03 GO:0008152 metabolic process
1.17 4.11e-03 GO:0044238 primary metabolic process
1.70 4.14e-03 GO:0006396 RNA processing
1.65 4.60e-03 GO:0012501 programmed cell death
2.04 4.83e-03 GO:0008380 RNA splicing
2.02 5.92e-03 GO:0051325 interphase
1.64 8.07e-03 GO:0006915 apoptosis
1.96 8.92e-03 GO:0007411 axon guidance
1.78 9.00e-03 GO:0007010 cytoskeleton organization
2.08 9.31e-03 GO:0007017 microtubule-based process
1.51 9.48e-03 GO:0022607 cellular component assembly
1.47 1.20e-02 GO:0044085 cellular component biogenesis
1.59 1.24e-02 GO:0046907 intracellular transport
1.60 1.29e-02 GO:0007155 cell adhesion
1.60 1.29e-02 GO:0022610 biological adhesion
1.32 1.38e-02 GO:0048519 negative regulation of biological process
2.23 1.53e-02 GO:0044087 regulation of cellular component biogenesis
1.99 1.56e-02 GO:0051130 positive regulation of cellular component organization
1.45 1.64e-02 GO:0051641 cellular localization
1.66 1.83e-02 GO:0051726 regulation of cell cycle
1.64 1.99e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.47 2.70e-02 GO:0051649 establishment of localization in cell
1.18 3.40e-02 GO:0032501 multicellular organismal process
6.03 4.28e-02 GO:0007026 negative regulation of microtubule depolymerization
2.16 4.42e-02 GO:0045664 regulation of neuron differentiation
1.56 4.42e-02 GO:0007267 cell-cell signaling

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 5.85e-17 GO:0005622 intracellular
1.17 1.05e-16 GO:0044424 intracellular part
1.25 6.71e-16 GO:0005737 cytoplasm
1.59 9.16e-13 GO:0044428 nuclear part
1.47 7.46e-11 GO:0043228 non-membrane-bounded organelle
1.47 7.46e-11 GO:0043232 intracellular non-membrane-bounded organelle
1.28 6.93e-10 GO:0044422 organelle part
1.28 8.02e-10 GO:0044446 intracellular organelle part
1.17 8.29e-10 GO:0043229 intracellular organelle
1.17 9.35e-10 GO:0043226 organelle
1.52 2.32e-09 GO:0005829 cytosol
3.08 2.51e-09 GO:0030424 axon
1.56 3.60e-09 GO:0031981 nuclear lumen
1.07 1.01e-08 GO:0044464 cell part
1.07 1.05e-08 GO:0005623 cell
2.24 4.50e-08 GO:0043005 neuron projection
1.25 5.14e-08 GO:0005634 nucleus
1.34 1.19e-07 GO:0032991 macromolecular complex
1.23 4.42e-07 GO:0044444 cytoplasmic part
1.91 7.18e-07 GO:0030054 cell junction
2.11 1.31e-06 GO:0045202 synapse
1.15 2.89e-06 GO:0043227 membrane-bounded organelle
1.15 3.14e-06 GO:0043231 intracellular membrane-bounded organelle
1.40 5.04e-06 GO:0031974 membrane-enclosed lumen
1.39 1.58e-05 GO:0070013 intracellular organelle lumen
1.58 3.60e-05 GO:0044430 cytoskeletal part
1.38 3.74e-05 GO:0043233 organelle lumen
1.51 4.83e-05 GO:0005654 nucleoplasm
1.47 4.91e-05 GO:0005856 cytoskeleton
1.32 5.39e-05 GO:0043234 protein complex
1.66 4.38e-04 GO:0031967 organelle envelope
1.78 6.06e-04 GO:0030529 ribonucleoprotein complex
2.15 8.15e-04 GO:0005635 nuclear envelope
2.41 8.30e-04 GO:0070161 anchoring junction
1.63 9.46e-04 GO:0031975 envelope
1.65 1.15e-03 GO:0015630 microtubule cytoskeleton
2.43 2.09e-03 GO:0005912 adherens junction
1.99 2.62e-03 GO:0005874 microtubule
1.97 2.76e-03 GO:0044456 synapse part
1.68 3.89e-03 GO:0005694 chromosome
2.22 5.18e-03 GO:0005819 spindle
1.67 1.38e-02 GO:0005730 nucleolus
1.80 1.47e-02 GO:0048471 perinuclear region of cytoplasm
5.36 2.10e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
2.65 2.14e-02 GO:0016585 chromatin remodeling complex
1.65 4.18e-02 GO:0044427 chromosomal part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.36 5.00e-27 GO:0005515 protein binding
1.16 1.08e-17 GO:0005488 binding
1.83 5.84e-08 GO:0003723 RNA binding
1.45 1.38e-07 GO:0000166 nucleotide binding
1.69 1.22e-04 GO:0019899 enzyme binding
1.78 4.24e-04 GO:0008092 cytoskeletal protein binding
1.62 1.27e-03 GO:0017111 nucleoside-triphosphatase activity
1.57 3.57e-03 GO:0016462 pyrophosphatase activity
1.57 4.23e-03 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.56 5.01e-03 GO:0016817 hydrolase activity, acting on acid anhydrides
2.52 2.10e-02 GO:0017124 SH3 domain binding
1.79 2.78e-02 GO:0016887 ATPase activity
7.23 3.51e-02 GO:0045295 gamma-catenin binding