Motif ID: SP1.p2

Z-value: 2.136


Transcription factors associated with SP1.p2:

Gene SymbolEntrez IDGene Name
SP1 6667 Sp1 transcription factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SP1chr12_+_53774422-0.446.7e-12Click!


Activity profile for motif SP1.p2.

activity profile for motif SP1.p2


Sorted Z-values histogram for motif SP1.p2

Sorted Z-values for motif SP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SP1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_6875686 31.596 PTMS
parathymosin
chr19_-_291335 31.547 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr19_+_54694118 27.514 NM_024075
TSEN34
tRNA splicing endonuclease 34 homolog (S. cerevisiae)
chr11_+_65686727 27.022 NM_006442
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr19_-_291168 25.397 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr20_+_43514340 23.060 NM_003404
NM_139323
YWHAB

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

chr16_+_2564000 22.692 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr19_+_50180492 22.665 PRMT1
protein arginine methyltransferase 1
chr17_-_80606095 22.268 NM_019613
WDR45L
WDR45-like
chr10_+_120863558 22.226 FAM45A
family with sequence similarity 45, member A
chr19_+_50180408 21.790 NM_001207042
NM_001536
NM_198318
PRMT1


protein arginine methyltransferase 1


chr10_+_134351272 21.720 NM_005539
INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
chr11_+_65686908 20.911 DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr18_+_12947972 20.627 NM_001013437
NM_031216
SEH1L

SEH1-like (S. cerevisiae)

chr1_-_20812727 20.073 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr8_+_146277789 19.792 NM_023080
C8orf33
chromosome 8 open reading frame 33
chrX_-_152989822 19.724 NM_005745
BCAP31
B-cell receptor-associated protein 31
chr20_+_44034632 19.555 NM_001197139
NM_001048221
NM_001048222
NM_001197140
NM_018478
DBNDD2




dysbindin (dystrobrevin binding protein 1) domain containing 2




chr3_-_149688638 19.101 NM_002628
NM_053024
PFN2

profilin 2

chr16_-_81129882 18.926 NM_004483
GCSH
glycine cleavage system protein H (aminomethyl carrier)
chr18_+_12948010 18.900 SEH1L
SEH1-like (S. cerevisiae)
chr1_+_955468 18.643 NM_198576
AGRN
agrin
chr6_-_4135701 18.272 NM_001166010
NM_006117
NM_206836
ECI2


enoyl-CoA delta isomerase 2


chr20_-_62130390 18.257 NM_001958
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr2_+_181845088 18.168 NM_182678
NM_006357
UBE2E3

ubiquitin-conjugating enzyme E2E 3

chr8_+_146277830 18.046 C8orf33
chromosome 8 open reading frame 33
chr20_+_62371218 17.775 SLC2A4RG
SLC2A4 regulator
chr11_-_2950593 17.704 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr9_+_140135742 17.640 TUBB4B
tubulin, beta 4B class IVb
chrX_-_152989522 17.582 NM_001139457
NM_001139441
BCAP31

B-cell receptor-associated protein 31

chr10_+_120863610 17.385 NM_207009
FAM45A
family with sequence similarity 45, member A
chr15_+_80445177 17.253 NM_000137
FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chrX_-_152989851 17.057 BCAP31
B-cell receptor-associated protein 31
chr20_+_32581725 17.030 RALY
RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr17_-_1083008 16.914 NM_021962
ABR
active BCR-related gene
chr16_+_730114 16.912 NM_005861
STUB1
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
chr5_+_138089118 16.763 CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chrX_+_153665258 16.602 NM_001493
GDI1
GDP dissociation inhibitor 1
chr10_-_126849066 16.567 NM_001329
CTBP2
C-terminal binding protein 2
chr20_+_56884749 16.328 NM_020673
RAB22A
RAB22A, member RAS oncogene family
chr1_-_1822501 16.099 GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr20_+_62371109 16.075 NM_020062
SLC2A4RG
SLC2A4 regulator
chr12_-_109125275 15.992 CORO1C
coronin, actin binding protein, 1C
chr20_+_43514350 15.928 YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr9_+_140135738 15.472 TUBB4B
tubulin, beta 4B class IVb
chrX_+_153665468 15.419 GDI1
GDP dissociation inhibitor 1
chr9_+_140135698 15.350 NM_006088
TUBB4B
tubulin, beta 4B class IVb
chr16_+_730419 15.150 STUB1
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
chr2_+_10443020 15.068 NM_002149
HPCAL1
hippocalcin-like 1
chr19_+_54695103 14.781 NM_001077446
TSEN34
tRNA splicing endonuclease 34 homolog (S. cerevisiae)
chr5_+_138089073 14.643 NM_001903
CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr12_+_6875468 14.591 NM_002824
PTMS
parathymosin
chr20_+_32581553 14.492 RALY
RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr3_+_49711751 14.481 APEH
N-acylaminoacyl-peptide hydrolase
chr10_-_126849010 14.437 CTBP2
C-terminal binding protein 2
chr12_-_118498893 14.383 NM_018639
WSB2
WD repeat and SOCS box containing 2
chr19_-_2015628 14.370 NM_017797
BTBD2
BTB (POZ) domain containing 2
chr20_+_44035203 14.275 NM_001048223
NM_001048224
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chrX_-_152989807 14.248


chrX_+_133594297 14.173 HPRT1
hypoxanthine phosphoribosyltransferase 1
chr2_+_235860616 14.166 NM_014521
SH3BP4
SH3-domain binding protein 4
chr1_+_955609 14.083 AGRN
agrin
chr2_+_181845368 13.977 UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr2_-_9770999 13.798 YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr3_+_49711434 13.655 NM_001640
APEH
N-acylaminoacyl-peptide hydrolase
chr12_-_13153200 13.593 NM_015987
HEBP1
heme binding protein 1
chr12_-_109125289 13.542 NM_014325
CORO1C
coronin, actin binding protein, 1C
chr11_-_66234176 13.522 MRPL11
mitochondrial ribosomal protein L11
chr15_+_80445340 13.515 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr18_+_11981421 13.511 NM_014214
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr4_-_1242882 13.480 NM_001012614
NM_001328
CTBP1

C-terminal binding protein 1

chr16_+_2563914 13.435 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr1_-_1822493 13.412 GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr20_-_23618382 13.346 NM_000099
CST3
cystatin C
chr6_-_13814546 13.317 NM_001031713
CCDC90A
coiled-coil domain containing 90A
chr16_+_89989686 13.296 NM_006086
TUBB3
tubulin, beta 3 class III
chr10_+_121485593 13.229 INPP5F
inositol polyphosphate-5-phosphatase F
chr16_+_2563977 13.213 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr2_-_9771101 13.171 NM_006826
YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr1_-_1822558 13.169 GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr16_+_730425 13.156 STUB1
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
chr3_+_100428133 13.092 NM_001007565
NM_001195479
NM_006070
TFG


TRK-fused gene


chr18_+_11981552 12.997 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr10_+_121485638 12.986 INPP5F
inositol polyphosphate-5-phosphatase F
chr20_+_32581880 12.873 RALY
RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr21_-_46237966 12.815 SUMO3
SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
chr8_+_26371461 12.768 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr12_-_109125254 12.718 CORO1C
coronin, actin binding protein, 1C
chr6_+_3000026 12.710 NM_000904
NQO2
NAD(P)H dehydrogenase, quinone 2
chr9_+_130922471 12.697 NM_024112
C9orf16
chromosome 9 open reading frame 16
chr17_+_40118696 12.627 NM_033133
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr12_-_13153047 12.624 HEBP1
heme binding protein 1
chr16_+_2563993 12.620 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr16_+_58497548 12.617 NM_020465
NDRG4
NDRG family member 4
chr20_+_32581426 12.572 NM_007367
NM_016732
RALY

RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))

chr9_+_131314669 12.559 NM_001130438
NM_001195532
NM_003127
SPTAN1


spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)


chr14_+_105941061 12.500 NM_001312
CRIP2
cysteine-rich protein 2
chr17_+_40118792 12.426 CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr5_-_179233772 12.373 NM_014275
MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr11_-_535532 12.289 NM_001130442
NM_005343
NM_176795
HRAS


v-Ha-ras Harvey rat sarcoma viral oncogene homolog


chr16_-_2723374 12.278 ERVK13-1
endogenous retrovirus group K13, member 1
chr20_+_17550598 12.242 NM_001011546
NM_006870
DSTN

destrin (actin depolymerizing factor)

chr1_-_32801606 12.112 NM_023009
MARCKSL1
MARCKS-like 1
chr8_-_30669934 12.066 PPP2CB
protein phosphatase 2, catalytic subunit, beta isozyme
chr1_-_1822516 12.018 NM_002074
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr7_-_151216596 11.970 RHEB
Ras homolog enriched in brain
chr19_-_54693453 11.948 MBOAT7
membrane bound O-acyltransferase domain containing 7
chr1_+_155290639 11.909 NM_001105203
NM_001105204
RUSC1

RUN and SH3 domain containing 1

chr17_-_20946088 11.857 NM_015276
USP22
ubiquitin specific peptidase 22
chr17_-_76183074 11.756 NM_003258
TK1
thymidine kinase 1, soluble
chr10_+_121485487 11.735 NM_001243195
NM_014937
INPP5F

inositol polyphosphate-5-phosphatase F

chrX_-_153775427 11.693 G6PD
glucose-6-phosphate dehydrogenase
chr6_-_3157696 11.672 NM_001069
TUBB2A
tubulin, beta 2A class IIa
chr5_+_141488314 11.661 NM_030571
NDFIP1
Nedd4 family interacting protein 1
chr4_-_1242742 11.649 CTBP1
C-terminal binding protein 1
chr1_+_116916029 11.569 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr13_-_110438896 11.520 NM_003749
IRS2
insulin receptor substrate 2
chr11_-_67169340 11.443 NM_001008709
NM_002708
NM_206873
PPP1CA


protein phosphatase 1, catalytic subunit, alpha isozyme


chr20_-_62601140 11.415 NM_020713
ZNF512B
zinc finger protein 512B
chr2_-_220252627 11.412 NM_012100
DNPEP
aspartyl aminopeptidase
chr5_-_10761344 11.209 NM_004394
DAP
death-associated protein
chr10_-_118764727 11.187 KIAA1598
KIAA1598
chr10_+_120863626 11.170 FAM45A
FAM45B
family with sequence similarity 45, member A
family with sequence similarity 45, member A pseudogene
chrX_+_133594225 11.134 HPRT1
hypoxanthine phosphoribosyltransferase 1
chr12_-_106532447 11.062 NUAK1
NUAK family, SNF1-like kinase, 1
chr19_-_4867705 11.015 NM_001164189
NM_001164194
NM_005817
PLIN3


perilipin 3


chr14_-_69446038 10.995 NM_001102
NM_001130004
NM_001130005
ACTN1


actinin, alpha 1


chr11_+_63448868 10.980 NM_006054
NM_201428
NM_201429
NM_201430
RTN3



reticulon 3



chr11_-_67169309 10.932 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr9_+_138371627 10.907 NM_014811
PPP1R26
protein phosphatase 1, regulatory subunit 26
chr11_-_67169252 10.843 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr3_+_49711816 10.838 APEH
N-acylaminoacyl-peptide hydrolase
chr16_+_29817810 10.814 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr19_+_33182689 10.808 NM_001105570
NUDT19
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr19_-_36605724 10.800 NM_006233
POLR2I
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
chr14_-_103523619 10.732 NM_006035
CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
chr3_-_52444016 10.692 BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr10_+_3109708 10.670 NM_002627
PFKP
phosphofructokinase, platelet
chr3_-_52443893 10.656 NM_004656
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr2_-_10588273 10.655 ODC1
ornithine decarboxylase 1
chr20_+_56885027 10.635 RAB22A
RAB22A, member RAS oncogene family
chr2_+_54683276 10.620 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr5_-_176900653 10.613 NM_004395
DBN1
drebrin 1
chr1_-_205719157 10.579 NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr11_-_64014140 10.533 PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr19_+_708766 10.529 NM_001040134
NM_002579
PALM

paralemmin

chr11_+_1968499 10.515 NM_021134
MRPL23
mitochondrial ribosomal protein L23
chr1_+_166808721 10.470 NM_017542
POGK
pogo transposable element with KRAB domain
chr1_-_167906277 10.458 NM_001143674
NM_015415
BRP44

brain protein 44

chr16_+_2563675 10.435 NM_001198569
NM_001694
ATP6V0C

ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c

chr5_-_16936371 10.432 NM_012334
MYO10
myosin X
chr10_-_126849556 10.425 NM_001083914
CTBP2
C-terminal binding protein 2
chr8_+_41348126 10.406 NM_001002296
GOLGA7
golgin A7
chr2_+_85198176 10.402 NM_020122
KCMF1
potassium channel modulatory factor 1
chr11_+_47586887 10.375 NM_001143984
NM_175732
PTPMT1

protein tyrosine phosphatase, mitochondrial 1

chr7_-_151216765 10.367 RHEB
Ras homolog enriched in brain
chr11_+_34937676 10.363 NM_001135024
NM_001166158
NM_003477
PDHX


pyruvate dehydrogenase complex, component X


chr16_+_30077146 10.340 ALDOA
aldolase A, fructose-bisphosphate
chr8_-_11725622 10.330 CTSB
cathepsin B
chr16_+_58497628 10.306 NDRG4
NDRG family member 4
chr2_-_215674292 10.290 NM_000465
BARD1
BRCA1 associated RING domain 1
chr11_+_833007 10.289 CD151
CD151 molecule (Raph blood group)
chr5_-_10761179 10.284 DAP
death-associated protein
chr4_+_175204827 10.272 NM_001040157
CEP44
centrosomal protein 44kDa
chr10_-_118764559 10.256 KIAA1598
KIAA1598
chr20_+_11871364 10.239 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr7_+_73868397 10.236 GTF2IRD1
GTF2I repeat domain containing 1
chr22_-_19166133 10.167 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr6_+_34204928 10.036 HMGA1
high mobility group AT-hook 1
chr1_-_33815411 10.026 PHC2
polyhomeotic homolog 2 (Drosophila)
chr20_+_57466509 10.002 GNAS
GNAS complex locus
chr11_-_67188614 9.996 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr17_+_37026111 9.990 NM_006148
LASP1
LIM and SH3 protein 1
chr1_-_33815340 9.988 PHC2
polyhomeotic homolog 2 (Drosophila)
chr11_+_832965 9.949 CD151
CD151 molecule (Raph blood group)
chr2_-_179315756 9.937 NM_003690
PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chr8_+_41348094 9.936 GOLGA7
golgin A7
chr19_+_2269515 9.936 NM_004152
OAZ1
SPPL2B
ornithine decarboxylase antizyme 1
signal peptide peptidase-like 2B
chr2_-_10952803 9.916 PDIA6
protein disulfide isomerase family A, member 6
chr11_-_134281725 9.911 NM_018644
NM_054025
B3GAT1

beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

chr11_+_832909 9.906 NM_001039490
NM_004357
NM_139029
NM_139030
CD151



CD151 molecule (Raph blood group)



chr19_-_55791428 9.904 HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr6_+_17393610 9.875 NM_006366
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr20_+_32581686 9.864 RALY
RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr16_+_30076993 9.842 NM_001243177
NM_184041
ALDOA

aldolase A, fructose-bisphosphate

chr22_-_50746000 9.802 NM_012401
PLXNB2
plexin B2
chr8_+_145064583 9.799 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr19_+_49497122 9.778 NM_006666
RUVBL2
RuvB-like 2 (E. coli)
chr19_-_4867638 9.775 PLIN3
perilipin 3
chr11_+_63754300 9.775 OTUB1
OTU domain, ubiquitin aldehyde binding 1
chr5_+_17217474 9.739 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr5_-_176900591 9.736 DBN1
drebrin 1
chr19_-_55791490 9.731 HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr11_-_507169 9.720 RNH1
ribonuclease/angiogenin inhibitor 1
chr11_-_12030622 9.689 NM_015881
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr8_+_41348105 9.631 GOLGA7
golgin A7
chr10_-_81205091 9.609 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr4_-_102268626 9.604 NM_000944
NM_001130691
NM_001130692
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr1_-_153606567 9.594 NM_001024210
S100A13
S100 calcium binding protein A13
chr4_-_71705613 9.584 NM_002092
GRSF1
G-rich RNA sequence binding factor 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.14 1.08e-69 GO:0009987 cellular process
1.22 4.13e-52 GO:0044237 cellular metabolic process
1.20 1.10e-50 GO:0008152 metabolic process
1.18 1.42e-48 GO:0065007 biological regulation
1.19 5.29e-46 GO:0050789 regulation of biological process
1.21 1.32e-45 GO:0044238 primary metabolic process
1.18 3.16e-39 GO:0050794 regulation of cellular process
1.23 8.29e-32 GO:0044260 cellular macromolecule metabolic process
1.21 3.25e-31 GO:0043170 macromolecule metabolic process
1.27 1.47e-29 GO:0006807 nitrogen compound metabolic process
1.26 1.76e-29 GO:0016043 cellular component organization
1.27 1.47e-28 GO:0034641 cellular nitrogen compound metabolic process
1.25 8.09e-28 GO:0071840 cellular component organization or biogenesis
1.28 2.32e-25 GO:0048518 positive regulation of biological process
1.28 3.40e-25 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.29 4.45e-24 GO:0048522 positive regulation of cellular process
1.27 5.47e-23 GO:0071842 cellular component organization at cellular level
1.20 1.08e-21 GO:0051716 cellular response to stimulus
1.26 2.44e-21 GO:0071841 cellular component organization or biogenesis at cellular level
1.20 5.09e-21 GO:0019222 regulation of metabolic process
1.27 3.38e-18 GO:0065008 regulation of biological quality
1.20 4.14e-18 GO:0080090 regulation of primary metabolic process
1.26 5.87e-18 GO:0042221 response to chemical stimulus
1.26 6.52e-18 GO:0048519 negative regulation of biological process
1.20 7.10e-18 GO:0031323 regulation of cellular metabolic process
1.19 7.76e-18 GO:0023052 signaling
1.27 1.64e-17 GO:0048523 negative regulation of cellular process
1.19 1.94e-16 GO:0032502 developmental process
1.20 2.35e-16 GO:0007165 signal transduction
1.24 3.55e-16 GO:0044249 cellular biosynthetic process
1.25 8.12e-16 GO:0090304 nucleic acid metabolic process
1.24 8.90e-16 GO:0044267 cellular protein metabolic process
1.28 1.47e-15 GO:0044281 small molecule metabolic process
1.23 2.65e-15 GO:0009058 biosynthetic process
1.34 4.70e-15 GO:0010033 response to organic substance
1.23 1.15e-14 GO:0006950 response to stress
1.19 2.21e-14 GO:0060255 regulation of macromolecule metabolic process
1.20 4.62e-14 GO:0019538 protein metabolic process
1.40 9.89e-14 GO:0008219 cell death
1.19 1.97e-13 GO:0048856 anatomical structure development
1.39 2.93e-13 GO:0016265 death
1.28 3.42e-13 GO:0006996 organelle organization
1.32 3.50e-13 GO:0009893 positive regulation of metabolic process
1.18 6.74e-13 GO:0007275 multicellular organismal development
1.29 1.23e-12 GO:0009056 catabolic process
1.32 2.95e-12 GO:0044248 cellular catabolic process
1.12 3.12e-12 GO:0050896 response to stimulus
1.32 3.59e-12 GO:0031325 positive regulation of cellular metabolic process
1.43 6.31e-12 GO:0009719 response to endogenous stimulus
1.44 1.31e-11 GO:0009725 response to hormone stimulus
1.24 1.39e-11 GO:0010467 gene expression
1.19 2.81e-11 GO:0048731 system development
1.25 3.88e-11 GO:0016070 RNA metabolic process
1.31 5.63e-11 GO:0010604 positive regulation of macromolecule metabolic process
1.19 6.72e-11 GO:0051171 regulation of nitrogen compound metabolic process
1.24 1.61e-10 GO:0006464 protein modification process
1.36 3.12e-10 GO:0051128 regulation of cellular component organization
1.19 3.84e-10 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24 4.18e-10 GO:0009059 macromolecule biosynthetic process
1.31 5.21e-10 GO:0043067 regulation of programmed cell death
1.24 5.50e-10 GO:0034645 cellular macromolecule biosynthetic process
1.24 6.92e-10 GO:0023051 regulation of signaling
1.31 7.19e-10 GO:0042981 regulation of apoptosis
1.18 7.53e-10 GO:0031326 regulation of cellular biosynthetic process
1.18 1.31e-09 GO:0009889 regulation of biosynthetic process
1.36 3.72e-09 GO:0012501 programmed cell death
1.30 4.38e-09 GO:0010941 regulation of cell death
1.40 4.93e-09 GO:0071822 protein complex subunit organization
1.21 7.31e-09 GO:0043412 macromolecule modification
1.22 8.15e-09 GO:0048583 regulation of response to stimulus
1.31 9.03e-09 GO:0032774 RNA biosynthetic process
1.41 9.99e-09 GO:0048666 neuron development
1.26 1.08e-08 GO:0051239 regulation of multicellular organismal process
1.24 1.21e-08 GO:0007399 nervous system development
1.30 1.29e-08 GO:0009605 response to external stimulus
1.15 1.44e-08 GO:0051179 localization
1.43 1.58e-08 GO:0031175 neuron projection development
1.31 2.30e-08 GO:0022008 neurogenesis
1.35 3.06e-08 GO:0006915 apoptosis
1.27 3.21e-08 GO:0050790 regulation of catalytic activity
1.30 3.59e-08 GO:0042127 regulation of cell proliferation
1.31 3.69e-08 GO:0048468 cell development
1.31 3.71e-08 GO:0051704 multi-organism process
1.32 3.81e-08 GO:0043933 macromolecular complex subunit organization
1.28 6.52e-08 GO:0051246 regulation of protein metabolic process
1.31 6.97e-08 GO:0048699 generation of neurons
1.24 7.74e-08 GO:0009966 regulation of signal transduction
1.44 7.76e-08 GO:0048812 neuron projection morphogenesis
1.29 1.07e-07 GO:0032879 regulation of localization
1.40 1.34e-07 GO:0044282 small molecule catabolic process
1.66 1.37e-07 GO:0022411 cellular component disassembly
1.66 1.37e-07 GO:0071845 cellular component disassembly at cellular level
1.18 1.51e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.25 1.99e-07 GO:0051641 cellular localization
1.17 2.70e-07 GO:0010556 regulation of macromolecule biosynthetic process
1.19 4.13e-07 GO:0030154 cell differentiation
1.23 4.47e-07 GO:0065009 regulation of molecular function
1.19 4.50e-07 GO:0048869 cellular developmental process
1.40 4.86e-07 GO:0032990 cell part morphogenesis
1.42 4.89e-07 GO:0006066 alcohol metabolic process
1.54 5.43e-07 GO:0048545 response to steroid hormone stimulus
1.43 5.47e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
1.40 5.68e-07 GO:0048858 cell projection morphogenesis
1.27 5.81e-07 GO:0010646 regulation of cell communication
1.40 6.62e-07 GO:0009628 response to abiotic stimulus
1.48 6.68e-07 GO:0009259 ribonucleotide metabolic process
1.30 7.37e-07 GO:0033554 cellular response to stress
1.28 8.14e-07 GO:0022414 reproductive process
1.27 8.40e-07 GO:0000003 reproduction
1.39 8.71e-07 GO:0000904 cell morphogenesis involved in differentiation
1.43 9.34e-07 GO:0007409 axonogenesis
1.22 9.92e-07 GO:0009653 anatomical structure morphogenesis
1.35 1.02e-06 GO:0051726 regulation of cell cycle
1.16 1.34e-06 GO:0010468 regulation of gene expression
1.27 1.37e-06 GO:0007049 cell cycle
1.34 1.37e-06 GO:0007167 enzyme linked receptor protein signaling pathway
1.35 1.77e-06 GO:0000902 cell morphogenesis
1.39 2.03e-06 GO:0007010 cytoskeleton organization
1.26 2.07e-06 GO:0022607 cellular component assembly
1.43 2.51e-06 GO:0006163 purine nucleotide metabolic process
1.36 2.59e-06 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.47 3.00e-06 GO:0009150 purine ribonucleotide metabolic process
1.44 3.39e-06 GO:0090066 regulation of anatomical structure size
1.26 3.50e-06 GO:0032268 regulation of cellular protein metabolic process
1.33 4.73e-06 GO:0030030 cell projection organization
1.32 4.84e-06 GO:0030182 neuron differentiation
1.77 5.14e-06 GO:0007265 Ras protein signal transduction
1.33 6.48e-06 GO:0032989 cellular component morphogenesis
1.28 6.75e-06 GO:0031328 positive regulation of cellular biosynthetic process
1.40 6.89e-06 GO:0072521 purine-containing compound metabolic process
1.22 7.62e-06 GO:0035556 intracellular signal transduction
1.28 7.83e-06 GO:0040011 locomotion
1.33 7.87e-06 GO:0071310 cellular response to organic substance
1.26 7.98e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.58 8.36e-06 GO:0044087 regulation of cellular component biogenesis
1.47 8.91e-06 GO:0032870 cellular response to hormone stimulus
1.27 1.13e-05 GO:0006351 transcription, DNA-dependent
1.36 1.25e-05 GO:0006753 nucleoside phosphate metabolic process
1.36 1.25e-05 GO:0009117 nucleotide metabolic process
1.16 1.28e-05 GO:0051252 regulation of RNA metabolic process
1.47 1.37e-05 GO:0009199 ribonucleoside triphosphate metabolic process
1.23 1.37e-05 GO:0044085 cellular component biogenesis
1.52 1.51e-05 GO:0006195 purine nucleotide catabolic process
1.36 1.88e-05 GO:0043068 positive regulation of programmed cell death
1.47 2.04e-05 GO:0009205 purine ribonucleoside triphosphate metabolic process
1.28 2.30e-05 GO:0046907 intracellular transport
1.24 2.31e-05 GO:0051649 establishment of localization in cell
1.29 2.39e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
1.44 2.40e-05 GO:0071495 cellular response to endogenous stimulus
1.46 2.63e-05 GO:0009144 purine nucleoside triphosphate metabolic process
1.25 2.68e-05 GO:0009892 negative regulation of metabolic process
1.51 2.74e-05 GO:0072523 purine-containing compound catabolic process
1.36 2.77e-05 GO:0070271 protein complex biogenesis
1.35 2.80e-05 GO:0043065 positive regulation of apoptosis
1.46 2.92e-05 GO:0009141 nucleoside triphosphate metabolic process
1.31 2.94e-05 GO:0046483 heterocycle metabolic process
1.27 3.11e-05 GO:0009891 positive regulation of biosynthetic process
1.28 3.47e-05 GO:0022402 cell cycle process
1.53 3.64e-05 GO:0009261 ribonucleotide catabolic process
1.53 3.87e-05 GO:0009154 purine ribonucleotide catabolic process
1.36 4.13e-05 GO:0006461 protein complex assembly
1.16 4.21e-05 GO:0006355 regulation of transcription, DNA-dependent
1.25 4.32e-05 GO:0070887 cellular response to chemical stimulus
1.53 4.39e-05 GO:0009203 ribonucleoside triphosphate catabolic process
1.53 4.39e-05 GO:0009207 purine ribonucleoside triphosphate catabolic process
1.13 4.62e-05 GO:0051234 establishment of localization
1.52 4.63e-05 GO:0051129 negative regulation of cellular component organization
1.33 5.00e-05 GO:0050878 regulation of body fluid levels
1.45 5.07e-05 GO:0044270 cellular nitrogen compound catabolic process
1.21 5.15e-05 GO:0033036 macromolecule localization
1.48 5.92e-05 GO:0009166 nucleotide catabolic process
1.52 6.39e-05 GO:0009146 purine nucleoside triphosphate catabolic process
1.28 6.71e-05 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.33 7.01e-05 GO:0051336 regulation of hydrolase activity
1.52 8.66e-05 GO:0009143 nucleoside triphosphate catabolic process
1.37 9.20e-05 GO:0008285 negative regulation of cell proliferation
1.42 9.92e-05 GO:0032535 regulation of cellular component size
1.33 1.23e-04 GO:0010942 positive regulation of cell death
1.48 1.26e-04 GO:0030036 actin cytoskeleton organization
1.17 1.27e-04 GO:0007166 cell surface receptor linked signaling pathway
1.27 1.32e-04 GO:0031399 regulation of protein modification process
1.45 1.32e-04 GO:0034655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process
1.45 1.32e-04 GO:0034656 nucleobase, nucleoside and nucleotide catabolic process
1.42 1.33e-04 GO:0007411 axon guidance
1.13 1.41e-04 GO:0006810 transport
1.33 1.55e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
2.49 1.75e-04 GO:0033261 regulation of S phase
1.34 2.14e-04 GO:0007599 hemostasis
1.25 2.27e-04 GO:0031324 negative regulation of cellular metabolic process
1.36 2.73e-04 GO:0043066 negative regulation of apoptosis
1.27 2.74e-04 GO:0016192 vesicle-mediated transport
1.62 2.77e-04 GO:0006184 GTP catabolic process
1.24 2.98e-04 GO:0010605 negative regulation of macromolecule metabolic process
1.33 3.14e-04 GO:0007596 blood coagulation
1.33 3.14e-04 GO:0050817 coagulation
1.25 3.43e-04 GO:0042592 homeostatic process
1.27 3.52e-04 GO:0051049 regulation of transport
1.59 3.58e-04 GO:0046039 GTP metabolic process
1.43 3.89e-04 GO:0030029 actin filament-based process
1.35 4.07e-04 GO:0043069 negative regulation of programmed cell death
1.25 4.08e-04 GO:0044093 positive regulation of molecular function
1.67 4.10e-04 GO:0043254 regulation of protein complex assembly
1.40 4.40e-04 GO:0044057 regulation of system process
1.27 4.45e-04 GO:0065003 macromolecular complex assembly
1.23 4.88e-04 GO:0006793 phosphorus metabolic process
1.23 4.88e-04 GO:0006796 phosphate metabolic process
1.36 5.48e-04 GO:0051247 positive regulation of protein metabolic process
1.40 5.78e-04 GO:0009894 regulation of catabolic process
1.31 6.53e-04 GO:0006928 cellular component movement
1.22 7.08e-04 GO:0007154 cell communication
1.34 7.55e-04 GO:0060548 negative regulation of cell death
1.52 8.34e-04 GO:0019318 hexose metabolic process
1.27 9.11e-04 GO:0010628 positive regulation of gene expression
1.55 9.34e-04 GO:0051493 regulation of cytoskeleton organization
1.26 9.37e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.34 1.04e-03 GO:0032583 regulation of gene-specific transcription
1.27 1.07e-03 GO:0043085 positive regulation of catalytic activity
1.55 1.11e-03 GO:0022415 viral reproductive process
1.08 1.19e-03 GO:0032501 multicellular organismal process
1.33 1.40e-03 GO:0010648 negative regulation of cell communication
1.57 1.48e-03 GO:0031344 regulation of cell projection organization
1.19 1.51e-03 GO:0002376 immune system process
1.36 1.76e-03 GO:0044419 interspecies interaction between organisms
1.26 2.14e-03 GO:0022403 cell cycle phase
1.46 2.47e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.40 2.52e-03 GO:0042493 response to drug
1.70 2.55e-03 GO:0008203 cholesterol metabolic process
1.26 2.61e-03 GO:0019220 regulation of phosphate metabolic process
1.26 2.61e-03 GO:0051174 regulation of phosphorus metabolic process
1.46 2.86e-03 GO:0005996 monosaccharide metabolic process
1.39 2.94e-03 GO:0046700 heterocycle catabolic process
1.22 2.97e-03 GO:0050793 regulation of developmental process
1.26 3.10e-03 GO:0009890 negative regulation of biosynthetic process
1.22 3.15e-03 GO:0009611 response to wounding
1.27 3.18e-03 GO:0051276 chromosome organization
1.47 3.19e-03 GO:0001701 in utero embryonic development
1.28 3.87e-03 GO:0042060 wound healing
1.35 3.94e-03 GO:0016568 chromatin modification
1.66 3.95e-03 GO:0016125 sterol metabolic process
1.34 4.27e-03 GO:0032270 positive regulation of cellular protein metabolic process
1.28 4.34e-03 GO:0000278 mitotic cell cycle
1.29 4.42e-03 GO:0006974 response to DNA damage stimulus
1.76 4.67e-03 GO:0032271 regulation of protein polymerization
1.37 4.79e-03 GO:0033043 regulation of organelle organization
1.31 4.80e-03 GO:0061024 membrane organization
1.50 4.90e-03 GO:0035270 endocrine system development
1.57 4.92e-03 GO:0019058 viral infectious cycle
1.34 4.96e-03 GO:0007264 small GTPase mediated signal transduction
1.47 5.11e-03 GO:0006457 protein folding
1.31 5.19e-03 GO:0016044 cellular membrane organization
1.32 5.29e-03 GO:0023057 negative regulation of signaling
1.63 5.72e-03 GO:0032984 macromolecular complex disassembly
1.63 5.72e-03 GO:0034623 cellular macromolecular complex disassembly
1.35 5.83e-03 GO:0012502 induction of programmed cell death
1.24 6.18e-03 GO:0071844 cellular component assembly at cellular level
1.30 6.38e-03 GO:0034621 cellular macromolecular complex subunit organization
1.35 6.82e-03 GO:0018193 peptidyl-amino acid modification
1.31 6.92e-03 GO:0051094 positive regulation of developmental process
1.29 7.53e-03 GO:0044283 small molecule biosynthetic process
1.25 7.63e-03 GO:0042325 regulation of phosphorylation
1.35 8.00e-03 GO:0006917 induction of apoptosis
1.25 9.21e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.25 9.48e-03 GO:0051254 positive regulation of RNA metabolic process
1.48 9.73e-03 GO:0014070 response to organic cyclic compound
1.32 1.00e-02 GO:0016477 cell migration
1.35 1.01e-02 GO:0043434 response to peptide hormone stimulus
1.54 1.03e-02 GO:0006006 glucose metabolic process
1.22 1.14e-02 GO:0048584 positive regulation of response to stimulus
1.35 1.18e-02 GO:0045597 positive regulation of cell differentiation
1.99 1.28e-02 GO:0051084 'de novo' posttranslational protein folding
1.38 1.30e-02 GO:0051270 regulation of cellular component movement
1.14 1.31e-02 GO:0048513 organ development
1.37 1.57e-02 GO:0051130 positive regulation of cellular component organization
1.25 1.58e-02 GO:0001932 regulation of protein phosphorylation
2.43 1.65e-02 GO:0051017 actin filament bundle assembly
1.46 1.75e-02 GO:0051051 negative regulation of transport
1.63 1.91e-02 GO:0043241 protein complex disassembly
1.63 1.91e-02 GO:0043624 cellular protein complex disassembly
1.25 2.06e-02 GO:0048878 chemical homeostasis
1.31 2.08e-02 GO:0009968 negative regulation of signal transduction
1.28 2.11e-02 GO:0019226 transmission of nerve impulse
1.28 2.11e-02 GO:0035637 multicellular organismal signaling
1.30 2.14e-02 GO:0043086 negative regulation of catalytic activity
1.29 2.18e-02 GO:0006325 chromatin organization
1.36 2.20e-02 GO:0048610 cellular process involved in reproduction
1.40 2.22e-02 GO:0051241 negative regulation of multicellular organismal process
1.25 2.27e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.67 2.33e-02 GO:0019080 viral genome expression
1.67 2.33e-02 GO:0019083 viral transcription
1.41 2.55e-02 GO:0071375 cellular response to peptide hormone stimulus
1.25 2.57e-02 GO:0006259 DNA metabolic process
1.50 2.57e-02 GO:0001666 response to hypoxia
1.22 2.64e-02 GO:2000026 regulation of multicellular organismal development
1.24 2.75e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.61 2.76e-02 GO:0032956 regulation of actin cytoskeleton organization
1.61 2.89e-02 GO:0006414 translational elongation
1.29 2.93e-02 GO:0044262 cellular carbohydrate metabolic process
1.62 3.02e-02 GO:0042176 regulation of protein catabolic process
1.24 3.16e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.22 3.21e-02 GO:0006468 protein phosphorylation
1.27 3.26e-02 GO:0008284 positive regulation of cell proliferation
1.29 3.30e-02 GO:0008283 cell proliferation
1.38 3.32e-02 GO:2000145 regulation of cell motility
1.27 3.36e-02 GO:0044092 negative regulation of molecular function
1.89 3.49e-02 GO:0006458 'de novo' protein folding
1.24 3.64e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.30 3.74e-02 GO:0040008 regulation of growth
1.40 3.82e-02 GO:0009314 response to radiation
1.47 3.87e-02 GO:0070482 response to oxygen levels
2.42 4.03e-02 GO:0007090 regulation of S phase of mitotic cell cycle
1.58 4.06e-02 GO:0032970 regulation of actin filament-based process
1.18 4.20e-02 GO:0008104 protein localization
1.29 4.28e-02 GO:0007268 synaptic transmission
1.68 4.28e-02 GO:0007015 actin filament organization
1.30 4.36e-02 GO:0016032 viral reproduction
1.34 4.45e-02 GO:0009991 response to extracellular stimulus
1.71 4.53e-02 GO:0031346 positive regulation of cell projection organization
1.77 4.58e-02 GO:0046364 monosaccharide biosynthetic process
1.73 4.62e-02 GO:0030832 regulation of actin filament length
1.74 4.63e-02 GO:0008064 regulation of actin polymerization or depolymerization
1.23 4.70e-02 GO:0045595 regulation of cell differentiation
1.36 4.81e-02 GO:0051345 positive regulation of hydrolase activity
1.26 4.86e-02 GO:0006935 chemotaxis
1.26 4.86e-02 GO:0042330 taxis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 5.22e-65 GO:0044424 intracellular part
1.12 4.84e-63 GO:0005622 intracellular
1.18 1.18e-57 GO:0005737 cytoplasm
1.13 2.53e-42 GO:0043226 organelle
1.13 6.97e-42 GO:0043229 intracellular organelle
1.20 6.40e-40 GO:0044444 cytoplasmic part
1.14 3.95e-38 GO:0043227 membrane-bounded organelle
1.38 1.00e-37 GO:0005829 cytosol
1.14 1.93e-37 GO:0043231 intracellular membrane-bounded organelle
1.18 5.33e-30 GO:0044422 organelle part
1.18 8.32e-30 GO:0044446 intracellular organelle part
1.16 2.04e-21 GO:0005634 nucleus
1.25 9.82e-18 GO:0031974 membrane-enclosed lumen
1.25 2.15e-17 GO:0043233 organelle lumen
1.37 2.21e-17 GO:0000267 cell fraction
1.26 3.05e-17 GO:0044428 nuclear part
1.25 3.25e-17 GO:0070013 intracellular organelle lumen
1.39 2.10e-14 GO:0005626 insoluble fraction
1.40 2.25e-14 GO:0005624 membrane fraction
1.26 2.26e-14 GO:0031981 nuclear lumen
1.03 3.47e-14 GO:0044464 cell part
1.03 3.97e-14 GO:0005623 cell
1.30 3.44e-13 GO:0005654 nucleoplasm
1.16 1.84e-11 GO:0032991 macromolecular complex
1.17 3.33e-10 GO:0043228 non-membrane-bounded organelle
1.17 3.33e-10 GO:0043232 intracellular non-membrane-bounded organelle
1.16 6.22e-09 GO:0043234 protein complex
1.18 1.39e-08 GO:0044459 plasma membrane part
1.43 9.66e-07 GO:0048471 perinuclear region of cytoplasm
1.24 1.74e-06 GO:0005783 endoplasmic reticulum
1.16 2.96e-06 GO:0031090 organelle membrane
1.23 2.35e-05 GO:0005794 Golgi apparatus
1.20 5.08e-05 GO:0005887 integral to plasma membrane
1.42 5.92e-05 GO:0015629 actin cytoskeleton
1.39 1.05e-04 GO:0005625 soluble fraction
1.17 1.15e-04 GO:0005856 cytoskeleton
1.32 2.08e-04 GO:0005768 endosome
1.17 2.10e-04 GO:0012505 endomembrane system
1.26 2.19e-04 GO:0015630 microtubule cytoskeleton
1.19 2.46e-04 GO:0031226 intrinsic to plasma membrane
1.24 3.57e-04 GO:0031982 vesicle
1.53 6.58e-04 GO:0005912 adherens junction
1.24 8.32e-04 GO:0044451 nucleoplasm part
1.50 8.69e-04 GO:0070161 anchoring junction
1.68 1.10e-03 GO:0042470 melanosome
1.68 1.10e-03 GO:0048770 pigment granule
1.23 1.22e-03 GO:0031410 cytoplasmic vesicle
1.23 1.36e-03 GO:0044432 endoplasmic reticulum part
1.26 3.80e-03 GO:0005694 chromosome
1.49 4.92e-03 GO:0045121 membrane raft
1.59 6.49e-03 GO:0005925 focal adhesion
1.99 6.52e-03 GO:0022625 cytosolic large ribosomal subunit
1.61 7.83e-03 GO:0016585 chromatin remodeling complex
1.38 8.97e-03 GO:0016323 basolateral plasma membrane
1.21 1.00e-02 GO:0031988 membrane-bounded vesicle
1.26 1.28e-02 GO:0044427 chromosomal part
1.21 1.30e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.25 1.34e-02 GO:0005730 nucleolus
1.41 1.81e-02 GO:0031252 cell leading edge
1.45 1.84e-02 GO:0044445 cytosolic part
1.54 1.86e-02 GO:0030055 cell-substrate junction
1.36 2.07e-02 GO:0000785 chromatin
1.54 2.11e-02 GO:0005924 cell-substrate adherens junction
1.34 2.27e-02 GO:0044440 endosomal part
2.09 2.84e-02 GO:0032154 cleavage furrow
1.40 3.44e-02 GO:0005819 spindle
1.46 3.58e-02 GO:0043235 receptor complex
1.34 3.91e-02 GO:0042598 vesicular fraction
1.33 4.20e-02 GO:0010008 endosome membrane
1.20 4.88e-02 GO:0042175 nuclear membrane-endoplasmic reticulum network

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.24 1.09e-79 GO:0005515 protein binding
1.12 2.20e-64 GO:0005488 binding
1.13 9.95e-14 GO:0003824 catalytic activity
1.21 1.07e-12 GO:0000166 nucleotide binding
1.40 1.17e-12 GO:0019899 enzyme binding
1.20 6.01e-09 GO:0017076 purine nucleotide binding
1.20 8.57e-09 GO:0032553 ribonucleotide binding
1.20 8.57e-09 GO:0032555 purine ribonucleotide binding
1.20 1.40e-08 GO:0035639 purine ribonucleoside triphosphate binding
1.43 1.68e-08 GO:0019904 protein domain specific binding
1.31 4.78e-07 GO:0042802 identical protein binding
1.20 9.52e-07 GO:0030554 adenyl nucleotide binding
1.20 1.25e-06 GO:0032559 adenyl ribonucleotide binding
1.35 1.34e-06 GO:0008092 cytoskeletal protein binding
1.20 2.66e-06 GO:0005524 ATP binding
1.26 1.50e-05 GO:0003723 RNA binding
1.40 1.45e-04 GO:0003779 actin binding
1.22 4.87e-04 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.26 1.03e-03 GO:0046983 protein dimerization activity
1.45 1.24e-03 GO:0003924 GTPase activity
1.54 1.51e-03 GO:0008022 protein C-terminus binding
1.72 2.43e-03 GO:0031625 ubiquitin protein ligase binding
1.12 2.49e-03 GO:0016787 hydrolase activity
1.32 4.09e-03 GO:0000988 protein binding transcription factor activity
1.32 4.09e-03 GO:0000989 transcription factor binding transcription factor activity
1.45 5.24e-03 GO:0003682 chromatin binding
1.32 5.47e-03 GO:0003712 transcription cofactor activity
1.21 8.75e-03 GO:0016462 pyrophosphatase activity
1.22 8.99e-03 GO:0017111 nucleoside-triphosphatase activity
1.18 1.17e-02 GO:0030528 transcription regulator activity
1.21 1.33e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.21 1.43e-02 GO:0016817 hydrolase activity, acting on acid anhydrides
1.36 1.65e-02 GO:0032403 protein complex binding
1.20 2.99e-02 GO:0016301 kinase activity
1.09 3.08e-02 GO:0003676 nucleic acid binding