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• Activity deltas table
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Motif ID: SREBF1,2.p2

Z-value: 1.607

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr13_+_113951537	58.019		LAMP1	lysosomal-associated membrane protein 1
chr13_+_113951589	55.313		LAMP1	lysosomal-associated membrane protein 1
chr13_+_113951461	52.717	NM_005561	LAMP1	lysosomal-associated membrane protein 1
chr19_+_40854529	35.401		PLD3	phospholipase D family, member 3
chr19_+_40854331	34.774	NM_001031696 NM_012268	PLD3	phospholipase D family, member 3
chr17_+_78075299	28.528	NM_000152 NM_001079803 NM_001079804	GAA	glucosidase, alpha; acid
chr17_+_78075390	27.735		GAA	glucosidase, alpha; acid
chr20_+_44520021	27.387		CTSA	cathepsin A
chr8_-_54755836	25.560	NM_015941 NM_213619	ATP6V1H	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr8_-_54755821	25.532		ATP6V1H	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr20_+_44519965	24.564		CTSA	cathepsin A
chr8_-_54755546	23.497	NM_213620	ATP6V1H	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr19_-_48018163	23.428		NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha
chr15_-_72668301	23.213	NM_000520	HEXA	hexosaminidase A (alpha polypeptide)
chr1_+_44440595	22.851	NM_001039457 NM_004047	ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr16_-_67514989	22.478	NM_004691	ATP6V0D1	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr1_+_44440623	22.396		ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr20_+_44519590	22.109	NM_000308 NM_001127695 NM_001167594	CTSA	cathepsin A
chr11_-_6640644	22.066		TPP1	tripeptidyl peptidase I
chr1_+_44440642	21.583		ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr15_-_73925555	21.490		NPTN	neuroplastin
chr10_-_73610958	21.307		PSAP	prosaposin
chr10_-_73611005	20.695		PSAP	prosaposin
chr20_+_44519924	20.439		CTSA	cathepsin A
chr5_-_172198160	20.336	NM_004417	DUSP1	dual specificity phosphatase 1
chr11_-_1785126	20.069		CTSD	cathepsin D
chr10_+_51827710	19.721		FAM21A	family with sequence similarity 21, member A
chr15_-_73925658	19.685	NM_001161363 NM_001161364 NM_012428 NM_017455	NPTN	neuroplastin
chr12_-_65153182	18.981		GNS	glucosamine (N-acetyl)-6-sulfatase
chr3_+_113465910	18.569		ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr3_+_113465860	18.501	NM_001690	ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr16_-_1525020	18.364		CLCN7	chloride channel 7
chr15_-_72668184	17.951		HEXA	hexosaminidase A (alpha polypeptide)
chr19_-_48018317	17.945	NM_003827	NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha
chr1_+_44440673	17.920		ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr11_-_6640578	17.221		TPP1	tripeptidyl peptidase I
chr19_+_7587436	17.018	NM_020533	MCOLN1	mucolipin 1
chrX_+_101380659	16.948	NM_080390	TCEAL2	transcription elongation factor A (SII)-like 2
chr2_+_220042948	16.934		FAM134A	family with sequence similarity 134, member A
chr12_-_65153189	16.763	NM_002076	GNS	glucosamine (N-acetyl)-6-sulfatase
chr9_+_115913266	16.692		SLC31A2	solute carrier family 31 (copper transporters), member 2
chr16_+_2570322	16.608	NM_001145815 NM_015944	AMDHD2	amidohydrolase domain containing 2
chr11_-_1785104	16.547		CTSD	cathepsin D
chr9_+_115913227	16.456	NM_001860	SLC31A2	solute carrier family 31 (copper transporters), member 2
chr19_-_48018277	16.375		NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha
chr11_-_6640645	16.245		TPP1	tripeptidyl peptidase I
chr3_+_158519911	15.754		MFSD1	major facilitator superfamily domain containing 1
chr2_+_228189919	15.423		MFF	mitochondrial fission factor
chr5_-_150537261	15.319		ANXA6	annexin A6
chr2_+_220042986	15.250		FAM134A	family with sequence similarity 134, member A
chr6_-_33386064	15.216	NM_001014433 NM_001014837 NM_001014838 NM_001014840 NM_015921	CUTA	cutA divalent cation tolerance homolog (E. coli)
chr3_+_158519888	14.670		MFSD1	major facilitator superfamily domain containing 1
chr19_-_10764449	14.621		LOC147727	uncharacterized LOC147727
chr11_-_1785087	14.521		CTSD	cathepsin D
chr5_-_150537306	14.502		ANXA6	annexin A6
chr20_-_39317875	14.433	NM_005461	MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr1_-_154531083	13.920	NM_017582	UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr11_+_121322848	13.911	NM_003105	SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr20_+_44520203	13.868		CTSA	cathepsin A
chr18_+_9708187	13.818	NM_006868	RAB31	RAB31, member RAS oncogene family
chr18_+_9708269	13.687		RAB31	RAB31, member RAS oncogene family
chrX_+_102470003	13.660	NM_001080425 NM_001127688	BEX4	brain expressed, X-linked 4
chr3_+_158519714	13.635	NM_001167903 NM_022736	MFSD1	major facilitator superfamily domain containing 1
chr17_-_35969401	13.619	NM_001163544 NM_001163545 NM_001163546 NM_001163547 NM_007247 NM_080550 NM_198882	SYNRG	synergin, gamma
chr22_+_35695872	13.404		TOM1	target of myb1 (chicken)
chr16_-_1525006	13.347		CLCN7	chloride channel 7
chr1_+_110162427	13.294	NM_139156	AMPD2	adenosine monophosphate deaminase 2
chr18_+_9708322	13.286		RAB31	RAB31, member RAS oncogene family
chr3_+_112280871	13.159	NM_017945	SLC35A5	solute carrier family 35, member A5
chr3_+_158519877	13.135		MFSD1	major facilitator superfamily domain containing 1
chr3_+_158519925	13.116		MFSD1	major facilitator superfamily domain containing 1
chrX_+_100663229	13.047		HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')
chr12_-_65153148	12.927		GNS	glucosamine (N-acetyl)-6-sulfatase
chrX_+_100663120	12.838	NM_001032393 NM_019597	HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')
chr1_+_110162459	12.695		AMPD2	adenosine monophosphate deaminase 2
chr3_+_128445024	12.619		RAB7A	RAB7A, member RAS oncogene family
chr1_-_40562909	12.462		PPT1	palmitoyl-protein thioesterase 1
chr16_+_85061303	12.429	NM_014732	KIAA0513	KIAA0513
chr16_-_5083913	12.423		NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr10_+_51827654	12.412	NM_001005751	FAM21C FAM21A	family with sequence similarity 21, member C family with sequence similarity 21, member A
chr1_-_40562917	12.381		PPT1	palmitoyl-protein thioesterase 1
chr16_-_5083933	12.353	NM_016256	NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr19_+_1067293	12.193		HMHA1	histocompatibility (minor) HA-1
chr10_+_46222647	12.170	NM_001169106 NM_001169107 NM_015262	FAM21C	family with sequence similarity 21, member C
chr16_-_1525040	12.142	NM_001114331 NM_001287	CLCN7	chloride channel 7
chr18_-_29523087	12.092	NM_014939	TRAPPC8	trafficking protein particle complex 8
chr1_-_1167421	11.904	NM_016176 NM_016547	SDF4	stromal cell derived factor 4
chr8_-_17941598	11.889		ASAH1	N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr10_-_73611041	11.885		PSAP	prosaposin
chr1_-_154928564	11.795	NM_020524	PBXIP1	pre-B-cell leukemia homeobox interacting protein 1
chr8_-_11725509	11.396		CTSB	cathepsin B
chr11_+_118938473	11.212	NM_021729	VPS11	vacuolar protein sorting 11 homolog (S. cerevisiae)
chr1_-_241520384	11.205		RGS7	regulator of G-protein signaling 7
chr2_-_197036262	11.161		STK17B	serine/threonine kinase 17b
chr16_-_88923233	10.854		GALNS	galactosamine (N-acetyl)-6-sulfate sulfatase
chr1_-_241520467	10.819	NM_002924	RGS7	regulator of G-protein signaling 7
chrX_+_100663205	10.797		HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')
chr10_-_73611050	10.766	NM_001042465 NM_001042466 NM_002778	PSAP	prosaposin
chr4_-_15656944	10.735		FBXL5	F-box and leucine-rich repeat protein 5
chr11_-_85780088	10.656		PICALM	phosphatidylinositol binding clathrin assembly protein
chr3_+_112280911	10.620		SLC35A5	solute carrier family 35, member A5
chr17_-_76124767	10.526		TMC6	transmembrane channel-like 6
chr11_+_118938528	10.502		VPS11	vacuolar protein sorting 11 homolog (S. cerevisiae)
chr12_+_12869818	10.382	NM_004064	CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr8_-_17941614	10.301		ASAH1	N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr1_-_39325317	10.299	NM_022157	RRAGC	Ras-related GTP binding C
chr22_-_39268230	10.284	NM_014292	CBX6	chromobox homolog 6
chr11_+_118938515	10.133		VPS11	vacuolar protein sorting 11 homolog (S. cerevisiae)
chr5_-_150537335	9.930	NM_001155	ANXA6	annexin A6
chr9_+_6757636	9.851	NM_001146694 NM_001146695 NM_015061	KDM4C	lysine (K)-specific demethylase 4C
chr7_-_30029284	9.835	NM_001145515 NM_014766 NM_001145513	SCRN1	secernin 1
chr22_+_35695792	9.782	NM_001135730 NM_001135732 NM_005488	TOM1	target of myb1 (chicken)
chr20_-_36156226	9.665		BLCAP	bladder cancer associated protein
chr15_-_72668740	9.586		HEXA	hexosaminidase A (alpha polypeptide)
chr16_-_28503622	9.554	NM_001042432	CLN3	ceroid-lipofuscinosis, neuronal 3
chr11_+_118938530	9.516		VPS11	vacuolar protein sorting 11 homolog (S. cerevisiae)
chr16_-_15736964	9.439	NM_001184998 NM_001184999 NM_014647	KIAA0430	KIAA0430
chr1_+_11866240	9.428		CLCN6	chloride channel 6
chr3_+_113465901	9.393		ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chrX_+_103031797	9.118		PLP1	proteolipid protein 1
chr22_-_21213069	9.104		PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha
chr22_-_21213099	8.985	NM_058004	PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha
chr16_+_87425946	8.985		MAP1LC3B	microtubule-associated protein 1 light chain 3 beta
chr22_-_21213012	8.924		PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha
chr14_+_96505566	8.707	NM_001252507	C14orf132	chromosome 14 open reading frame 132
chr11_-_6640661	8.640	NM_000391	TPP1	tripeptidyl peptidase I
chr20_-_4795768	8.631	NM_170774	RASSF2	Ras association (RalGDS/AF-6) domain family member 2
chr20_-_36156282	8.619	NM_001167820 NM_006698	BLCAP	bladder cancer associated protein
chr8_-_11725622	8.580		CTSB	cathepsin B
chr13_-_50159706	8.553	NM_018191	RCBTB1	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr2_+_220042901	8.516	NM_024293	FAM134A	family with sequence similarity 134, member A
chr15_+_89182038	8.503	NM_002201	ISG20	interferon stimulated exonuclease gene 20kDa
chr17_+_42422627	8.480		GRN	granulin
chr16_+_19567021	8.469		C16orf62	chromosome 16 open reading frame 62
chr19_+_1067536	8.454		HMHA1	histocompatibility (minor) HA-1
chr20_-_36156082	8.450	NM_001167822 NM_001167821	BLCAP	bladder cancer associated protein
chr12_+_51632620	8.423		DAZAP2	DAZ associated protein 2
chr9_+_117349993	8.290	NM_004888	ATP6V1G1	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr13_-_50159628	8.279		RCBTB1	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chrX_-_15872921	8.275		AP1S2	adaptor-related protein complex 1, sigma 2 subunit
chr12_-_65153055	8.263		GNS	glucosamine (N-acetyl)-6-sulfatase
chr12_+_51632654	8.216		DAZAP2	DAZ associated protein 2
chr1_-_154600383	8.167		ADAR	adenosine deaminase, RNA-specific
chr6_+_160390128	8.107	NM_000876	IGF2R	insulin-like growth factor 2 receptor
chr19_+_50016500	8.078		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr3_-_4508939	8.062		SUMF1	sulfatase modifying factor 1
chr3_+_128444978	8.035	NM_004637	RAB7A	RAB7A, member RAS oncogene family
chr6_-_33385662	8.018		CUTA	cutA divalent cation tolerance homolog (E. coli)
chr16_+_2564000	7.993		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr19_+_50016490	7.948		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chrX_+_103031753	7.944	NM_000533 NM_199478	PLP1	proteolipid protein 1
chr12_+_51632507	7.920	NM_001136264 NM_001136266 NM_001136267 NM_001136268 NM_001136269 NM_014764	DAZAP2	DAZ associated protein 2
chr12_+_112451151	7.913	NM_001034025 NM_006817	ERP29	endoplasmic reticulum protein 29
chrX_-_15872882	7.908		AP1S2	adaptor-related protein complex 1, sigma 2 subunit
chr16_+_87425998	7.904		MAP1LC3B	microtubule-associated protein 1 light chain 3 beta
chr18_+_9708299	7.889		RAB31	RAB31, member RAS oncogene family
chr22_+_35777087	7.868		HMOX1	heme oxygenase (decycling) 1
chr12_+_51632589	7.808		DAZAP2	DAZ associated protein 2
chr1_-_1167358	7.742		SDF4	stromal cell derived factor 4
chr16_+_87425874	7.695		MAP1LC3B	microtubule-associated protein 1 light chain 3 beta
chr12_-_109027654	7.688	NM_003006	SELPLG	selectin P ligand
chr7_+_151722774	7.661	NM_022087	GALNT11	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr20_+_57428035	7.644	NM_001077490 NM_080425	GNAS	GNAS complex locus
chr12_+_6833425	7.605	NM_001164093	COPS7A	COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
chrX_-_15872938	7.597		AP1S2	adaptor-related protein complex 1, sigma 2 subunit
chr16_+_2563993	7.536		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr17_+_25621141	7.435		WSB1	WD repeat and SOCS box containing 1
chr7_+_149570004	7.432	NM_001100592 NM_145230	ATP6V0E2	ATPase, H+ transporting V0 subunit e2
chrX_+_153656977	7.431	NM_001183	ATP6AP1	ATPase, H+ transporting, lysosomal accessory protein 1
chrX_-_15872905	7.421
chrX_+_153657025	7.415		ATP6AP1	ATPase, H+ transporting, lysosomal accessory protein 1
chr8_-_11725595	7.401		CTSB	cathepsin B
chr11_-_1785190	7.356	NM_001909	CTSD	cathepsin D
chr3_+_5021096	7.332	NM_003670	BHLHE40	basic helix-loop-helix family, member e40
chr9_-_123476578	7.296	NM_001080497	MEGF9	multiple EGF-like-domains 9
chr16_+_2563914	7.274		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr19_+_18208596	7.271	NM_015016	MAST3	microtubule associated serine/threonine kinase 3
chr8_-_11725587	7.248		CTSB	cathepsin B
chr16_+_2563977	7.238		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chrX_+_153657119	7.236		ATP6AP1	ATPase, H+ transporting, lysosomal accessory protein 1
chr8_+_26240522	7.193	NM_004331	BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr12_-_109027565	7.177		SELPLG	selectin P ligand
chr6_+_138188352	7.125	NM_006290	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chr11_-_85780105	7.083	NM_001008660 NM_001206946 NM_007166	PICALM	phosphatidylinositol binding clathrin assembly protein
chr16_-_28503079	7.061	NM_000086	CLN3	ceroid-lipofuscinosis, neuronal 3
chr8_-_17941617	7.038	NM_177924	ASAH1	N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr16_-_88923348	6.972	NM_000512	GALNS	galactosamine (N-acetyl)-6-sulfate sulfatase
chr1_-_154928595	6.970		PBXIP1	pre-B-cell leukemia homeobox interacting protein 1
chrX_-_13835313	6.932	NM_001001995 NM_001001996 NM_005278	GPM6B	glycoprotein M6B
chr7_+_108210308	6.929		DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9
chr17_+_42422490	6.908	NM_002087	GRN	granulin
chr19_+_1067114	6.881	NM_012292	HMHA1	histocompatibility (minor) HA-1
chr3_+_147127151	6.878	NM_003412	ZIC1	Zic family member 1
chr6_-_33385814	6.877
chr3_+_5021141	6.862		BHLHE40	basic helix-loop-helix family, member e40
chr16_+_11762235	6.777	NM_003498	SNN	stannin
chr7_+_151722842	6.765		GALNT11	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr13_+_42846255	6.669	NM_016248	AKAP11	A kinase (PRKA) anchor protein 11
chr11_+_65479472	6.663	NM_001206833 NM_006388 NM_182709 NM_182710	KAT5	K(lysine) acetyltransferase 5
chr14_-_74551159	6.647	NM_005589	ALDH6A1	aldehyde dehydrogenase 6 family, member A1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
9.04	2.08e-08	GO:0015682	ferric iron transport
9.04	2.08e-08	GO:0033572	transferrin transport
1.15	6.12e-07	GO:0009987	cellular process
7.84	4.85e-06	GO:0015988	energy coupled proton transport, against electrochemical gradient
7.84	4.85e-06	GO:0015991	ATP hydrolysis coupled proton transport
2.29	5.96e-06	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.73	1.52e-05	GO:0033036	macromolecule localization
1.39	2.61e-05	GO:0051179	localization
5.12	3.52e-05	GO:0006818	hydrogen transport
4.79	4.35e-05	GO:0055072	iron ion homeostasis
1.96	4.86e-05	GO:0016192	vesicle-mediated transport
1.42	8.08e-05	GO:0051234	establishment of localization
1.42	9.95e-05	GO:0006810	transport
5.08	1.08e-04	GO:0006826	iron ion transport
3.45	1.12e-04	GO:0008286	insulin receptor signaling pathway
4.73	1.31e-04	GO:0006879	cellular iron ion homeostasis
4.99	1.41e-04	GO:0015992	proton transport
2.47	1.42e-04	GO:0071495	cellular response to endogenous stimulus
1.74	2.39e-04	GO:0008104	protein localization
1.24	2.55e-04	GO:0044237	cellular metabolic process
3.76	2.85e-04	GO:0000041	transition metal ion transport
1.97	3.79e-04	GO:0007167	enzyme linked receptor protein signaling pathway
5.27	4.39e-04	GO:0007033	vacuole organization
2.98	4.76e-04	GO:0032869	cellular response to insulin stimulus
1.65	6.45e-04	GO:0051641	cellular localization
2.66	1.49e-03	GO:0048011	nerve growth factor receptor signaling pathway
6.70	2.10e-03	GO:0007040	lysosome organization
1.76	3.25e-03	GO:0015031	protein transport
1.75	3.30e-03	GO:0045184	establishment of protein localization
2.33	3.45e-03	GO:0032870	cellular response to hormone stimulus
2.56	4.97e-03	GO:0071375	cellular response to peptide hormone stimulus
2.16	6.80e-03	GO:0051056	regulation of small GTPase mediated signal transduction
1.63	7.63e-03	GO:0051649	establishment of localization in cell
2.03	9.83e-03	GO:0016044	cellular membrane organization
1.82	1.11e-02	GO:0009719	response to endogenous stimulus
2.02	1.12e-02	GO:0061024	membrane organization
1.18	1.26e-02	GO:0008152	metabolic process
1.90	1.53e-02	GO:0019725	cellular homeostasis
2.44	1.90e-02	GO:0032868	response to insulin stimulus
1.83	2.17e-02	GO:0009725	response to hormone stimulus
1.20	2.29e-02	GO:0044238	primary metabolic process
3.90	2.30e-02	GO:0002756	MyD88-independent toll-like receptor signaling pathway
2.15	2.45e-02	GO:0043434	response to peptide hormone stimulus
1.80	2.57e-02	GO:0071310	cellular response to organic substance
2.37	3.25e-02	GO:0006897	endocytosis
2.37	3.25e-02	GO:0010324	membrane invagination
1.43	3.27e-02	GO:0048583	regulation of response to stimulus
2.02	4.51e-02	GO:0007264	small GTPase mediated signal transduction
2.51	4.73e-02	GO:0034220	ion transmembrane transport

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
3.93	5.53e-20	GO:0005773	vacuole
1.32	6.37e-18	GO:0005737	cytoplasm
1.42	1.33e-16	GO:0044444	cytoplasmic part
4.73	6.16e-14	GO:0005774	vacuolar membrane
3.60	1.78e-13	GO:0000323	lytic vacuole
3.60	1.78e-13	GO:0005764	lysosome
4.52	3.33e-13	GO:0044437	vacuolar part
2.69	1.56e-10	GO:0005768	endosome
2.19	4.21e-10	GO:0031982	vesicle
2.19	1.08e-09	GO:0031410	cytoplasmic vesicle
2.22	1.64e-09	GO:0016023	cytoplasmic membrane-bounded vesicle
2.21	1.76e-09	GO:0031988	membrane-bounded vesicle
1.16	1.86e-09	GO:0005622	intracellular
1.16	5.03e-09	GO:0044424	intracellular part
10.85	2.49e-08	GO:0033176	proton-transporting V-type ATPase complex
4.28	3.48e-08	GO:0005765	lysosomal membrane
1.20	2.09e-07	GO:0043227	membrane-bounded organelle
1.20	2.58e-07	GO:0043231	intracellular membrane-bounded organelle
1.55	1.81e-06	GO:0005829	cytosol
3.71	8.05e-06	GO:0005770	late endosome
1.27	9.58e-06	GO:0044446	intracellular organelle part
1.27	1.13e-05	GO:0044422	organelle part
1.51	1.46e-05	GO:0031090	organelle membrane
1.16	1.87e-05	GO:0043226	organelle
1.16	1.97e-05	GO:0043229	intracellular organelle
2.56	1.17e-04	GO:0010008	endosome membrane
3.86	1.22e-04	GO:0042470	melanosome
3.86	1.22e-04	GO:0048770	pigment granule
5.47	1.26e-04	GO:0016469	proton-transporting two-sector ATPase complex
2.54	1.42e-04	GO:0044440	endosomal part
3.04	4.08e-04	GO:0005769	early endosome
15.07	1.11e-03	GO:0033179	proton-transporting V-type ATPase, V0 domain
1.80	7.65e-03	GO:0044431	Golgi apparatus part
2.58	1.06e-02	GO:0030136	clathrin-coated vesicle
7.03	1.10e-02	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain
4.02	1.17e-02	GO:0005798	Golgi-associated vesicle
1.56	1.79e-02	GO:0005794	Golgi apparatus
10.05	2.03e-02	GO:0033180	proton-transporting V-type ATPase, V1 domain
2.30	3.59e-02	GO:0030135	coated vesicle
9.04	3.88e-02	GO:0016471	vacuolar proton-transporting V-type ATPase complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.30	2.02e-11	GO:0005515	protein binding
9.04	7.87e-05	GO:0046961	proton-transporting ATPase activity, rotational mechanism
1.10	1.21e-03	GO:0005488	binding
6.03	1.52e-03	GO:0019829	cation-transporting ATPase activity
1.91	8.62e-03	GO:0030695	GTPase regulator activity
3.67	1.12e-02	GO:0042625	ATPase activity, coupled to transmembrane movement of ions
3.17	1.17e-02	GO:0015078	hydrogen ion transmembrane transporter activity
1.86	1.70e-02	GO:0060589	nucleoside-triphosphatase regulator activity