Motif ID: SRY.p2

Z-value: 1.633


Transcription factors associated with SRY.p2:

Gene SymbolEntrez IDGene Name
SRY 6736 sex determining region Y

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SRYchrY_-_26554780.351.5e-07Click!


Activity profile for motif SRY.p2.

activity profile for motif SRY.p2


Sorted Z-values histogram for motif SRY.p2

Sorted Z-values for motif SRY.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SRY.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_195310985 52.095 NM_001647
APOD
apolipoprotein D
chr3_+_39509069 50.245 NM_182935
MOBP
myelin-associated oligodendrocyte basic protein
chr3_-_195310770 48.548 APOD
apolipoprotein D
chrX_-_13835213 36.508 GPM6B
glycoprotein M6B
chr8_+_80523048 35.553 NM_001199214
NM_007029
STMN2

stathmin-like 2

chr5_+_36606456 35.393 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr4_-_176733413 32.955 GPM6A
glycoprotein M6A
chr5_+_36606667 32.321 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_+_71502700 32.266 MAP1B
microtubule-associated protein 1B
chr8_-_110655418 28.880 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr5_+_140739589 27.131 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr18_+_29171729 25.198 NM_000371
TTR
transthyretin
chrX_-_13835187 24.909 GPM6B
glycoprotein M6B
chr12_-_16758312 23.807 NM_001243611
LMO3
LIM domain only 3 (rhombotin-like 2)
chr4_-_88450243 23.514 SPARCL1
SPARC-like 1 (hevin)
chr4_-_88450601 22.946 NM_001128310
NM_004684
SPARCL1

SPARC-like 1 (hevin)

chr5_+_173472737 22.702 HMP19
HMP19 protein
chr11_+_112831968 22.654 NM_000615
NM_001076682
NM_001242607
NM_001242608
NM_181351
NCAM1




neural cell adhesion molecule 1




chr5_+_173472692 22.099 NM_015980
HMP19
HMP19 protein
chr12_-_45307710 21.945 NM_001145110
NELL2
NEL-like 2 (chicken)
chrX_-_13835012 21.345 GPM6B
glycoprotein M6B
chr12_+_79439432 20.807 NM_001135806
SYT1
synaptotagmin I
chr2_+_149633173 20.196


chr5_-_146435589 19.984 NM_181674
NM_181676
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr19_+_30863318 19.936 NM_014717
ZNF536
zinc finger protein 536
chrX_-_13835313 19.575 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr16_+_24266873 19.184 NM_006539
CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr5_+_140247767 19.049 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr12_-_91573264 18.848 NM_133503
DCN
decorin
chrX_+_103031797 18.073 PLP1
proteolipid protein 1
chr11_-_72380107 17.743 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr16_+_58534045 17.666 NM_001242833
NM_001242834
NM_001242835
NM_001242836
NDRG4



NDRG family member 4



chr12_-_9268440 17.437 A2M
alpha-2-macroglobulin
chr14_-_60097223 17.241 RTN1
reticulon 1
chr1_-_57045129 17.167 PPAP2B
phosphatidic acid phosphatase type 2B
chr11_+_73359734 17.043 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr2_-_2334887 16.859 NM_015025
MYT1L
myelin transcription factor 1-like
chr12_-_9268522 16.748 NM_000014
A2M
alpha-2-macroglobulin
chr8_+_85095501 16.446 NM_173848
RALYL
RALY RNA binding protein-like
chr2_-_174767282 16.360


chr14_-_60097314 16.274 RTN1
reticulon 1
chr21_+_41239346 16.248 NM_006198
PCP4
Purkinje cell protein 4
chr12_-_9268513 16.236 A2M
alpha-2-macroglobulin
chr1_+_151032683 16.026 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_155853546 15.915 SYT11
synaptotagmin XI
chr18_-_52988916 15.738 NM_001243234
NM_001243235
TCF4

transcription factor 4

chr1_+_151032866 15.714 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_160085519 15.583 NM_000702
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chrX_+_103031753 15.126 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr12_-_16757944 15.101 LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_+_151032880 14.747 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr6_-_52710892 14.327 NM_153699
GSTA5
glutathione S-transferase alpha 5
chr1_-_57044980 14.194 PPAP2B
phosphatidic acid phosphatase type 2B
chr13_-_45048436 13.991 NM_001243798
TSC22D1
TSC22 domain family, member 1
chr1_-_156217717 13.906 NM_198406
NM_024897
PAQR6

progestin and adipoQ receptor family member VI

chr7_+_149570004 13.899 NM_001100592
NM_145230
ATP6V0E2

ATPase, H+ transporting V0 subunit e2

chr1_-_57045235 13.587 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr1_-_182357871 12.846 GLUL
glutamate-ammonia ligase
chr22_-_19512859 12.844 NM_001130861
NM_003277
CLDN5

claudin 5

chr1_-_182357757 12.632 GLUL
glutamate-ammonia ligase
chrX_+_103031433 12.630 NM_001128834
PLP1
proteolipid protein 1
chr14_+_92788924 12.601 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr3_+_115342302 12.452 GAP43
growth associated protein 43
chr2_-_224467095 12.438 SCG2
secretogranin II
chrX_-_13956644 12.287 NM_001001994
GPM6B
glycoprotein M6B
chr1_+_50571963 12.218 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr15_+_80696569 12.152 NM_014862
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr12_-_9268475 12.060 A2M
alpha-2-macroglobulin
chr11_+_71791376 12.005 NM_001145307
NM_001145308
NM_001205138
NM_145309
LRTOMT



leucine rich transmembrane and 0-methyltransferase domain containing



chr1_+_204913353 11.995 NM_001160331
NFASC
neurofascin
chr19_-_37019169 11.984 NM_001012756
NM_001166036
NM_001166037
NM_001166038
ZNF260



zinc finger protein 260



chr8_-_27115935 11.945 STMN4
stathmin-like 4
chr8_+_80523351 11.937 STMN2
stathmin-like 2
chrX_-_100914816 11.909 NM_014782
NM_177949
ARMCX2

armadillo repeat containing, X-linked 2

chr18_-_21852189 11.690 NM_018030
OSBPL1A
oxysterol binding protein-like 1A
chr5_+_140771482 11.672 NM_014004
NM_032088
PCDHGA8

protocadherin gamma subfamily A, 8

chr3_+_115342150 11.670 NM_001130064
NM_002045
GAP43

growth associated protein 43

chr14_-_21493122 11.660 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr3_+_133464883 11.657 NM_001063
TF
transferrin
chr2_-_86564632 11.623 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr15_+_43885251 11.384 NM_020990
CKMT1B
CKMT1A
creatine kinase, mitochondrial 1B
creatine kinase, mitochondrial 1A
chr8_+_80523339 11.377 STMN2
stathmin-like 2
chr3_-_114343052 11.284 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr16_-_21314371 11.282 NM_001014444
NM_001888
CRYM

crystallin, mu

chr15_+_66874506 11.247


chr11_+_113931228 11.207 NM_001018011
ZBTB16
zinc finger and BTB domain containing 16
chr11_-_35440514 11.174 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr12_-_16760935 11.172 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr1_+_84609941 11.111 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_+_88896838 11.089 SPP1
secreted phosphoprotein 1
chr1_-_163113938 10.858 RGS5
regulator of G-protein signaling 5
chrX_+_91090459 10.770 NM_001168360
NM_001168361
NM_001168362
NM_001168363
PCDH11X



protocadherin 11 X-linked



chr12_-_11548485 10.765 NM_006248
PRB1
PRB2
proline-rich protein BstNI subfamily 1
proline-rich protein BstNI subfamily 2
chr8_-_18666295 10.677 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr8_+_80523304 10.639 STMN2
stathmin-like 2
chr8_+_105352050 10.611 NM_030788
TM7SF4
transmembrane 7 superfamily member 4
chr12_-_16759430 10.563 LMO3
LIM domain only 3 (rhombotin-like 2)
chr2_-_224467049 10.544 SCG2
secretogranin II
chr8_+_80523376 10.486 STMN2
stathmin-like 2
chr10_+_111967302 10.454 NM_130439
MXI1
MAX interactor 1
chr2_-_175869910 10.382 NM_001822
NM_001025201
CHN1

chimerin (chimaerin) 1

chr11_+_57365026 10.235 NM_000062
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr12_-_45270071 10.158 NELL2
NEL-like 2 (chicken)
chr4_-_176734181 10.099 NM_201591
GPM6A
glycoprotein M6A
chr8_+_22210311 10.092 PIWIL2
piwi-like 2 (Drosophila)
chr11_+_112832089 10.082 NCAM1
neural cell adhesion molecule 1
chr12_-_16758839 10.038 NM_001243612
LMO3
LIM domain only 3 (rhombotin-like 2)
chr16_+_15528324 10.003 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr12_-_21487831 10.001 NM_021094
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr4_-_90759446 9.991 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr10_-_62332666 9.940 NM_001204404
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr2_-_175712276 9.891 NM_001206602
CHN1
chimerin (chimaerin) 1
chr1_-_57045214 9.799 PPAP2B
phosphatidic acid phosphatase type 2B
chr1_+_36748164 9.701 THRAP3
thyroid hormone receptor associated protein 3
chr6_-_52628272 9.698 NM_000846
GSTA2
glutathione S-transferase alpha 2
chr16_+_58497628 9.696 NDRG4
NDRG family member 4
chr1_+_50574601 9.644 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr4_+_71587674 9.639 NM_001037442
NM_014961
RUFY3

RUN and FYVE domain containing 3

chr2_-_166060552 9.635 NM_001081676
NM_001081677
NM_006922
SCN3A


sodium channel, voltage-gated, type III, alpha subunit


chr12_-_16759531 9.559 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr4_+_41614911 9.541 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr16_+_58497548 9.475 NM_020465
NDRG4
NDRG family member 4
chr7_+_86273219 9.413 NM_000840
GRM3
glutamate receptor, metabotropic 3
chr8_-_27115897 9.404 NM_030795
STMN4
stathmin-like 4
chr1_+_66458389 9.372 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chr1_+_163038564 9.183 NM_005613
RGS4
regulator of G-protein signaling 4
chr8_-_110620220 9.162 SYBU
syntabulin (syntaxin-interacting)
chr7_+_26400503 8.918 NM_001199837
SNX10
sorting nexin 10
chr4_+_71263598 8.865 NM_021225
PROL1
proline rich, lacrimal 1
chr17_-_29648631 8.849 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr2_+_31456879 8.822 NM_014600
EHD3
EH-domain containing 3
chr9_-_123476578 8.655 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr1_+_66797775 8.584 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr19_-_17375522 8.581 NM_031941
USHBP1
Usher syndrome 1C binding protein 1
chr7_+_106505876 8.575 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr18_-_53177999 8.549 NM_001243231
TCF4
transcription factor 4
chr4_+_113970784 8.526 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr8_-_40755328 8.504 NM_001135731
NM_024645
ZMAT4

zinc finger, matrin-type 4

chr8_-_134309448 8.500 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr17_+_38119225 8.457 NM_178171
GSDMA
gasdermin A
chr6_+_39760772 8.413 NM_015345
DAAM2
dishevelled associated activator of morphogenesis 2
chr19_-_14939275 8.413 NM_017506
OR7A5
olfactory receptor, family 7, subfamily A, member 5
chr5_-_146460991 8.403 NM_181677
NM_181678
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr22_-_50523853 8.368 MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr7_-_37488554 8.358 NM_014800
ELMO1
engulfment and cell motility 1
chr7_+_106505696 8.353 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr1_-_177133818 8.305 ASTN1
astrotactin 1
chr5_+_140743755 8.248 NM_018918
NM_032054
PCDHGA5

protocadherin gamma subfamily A, 5

chr2_-_71454200 8.225 NM_020459
PAIP2B
poly(A) binding protein interacting protein 2B
chr19_-_21950322 8.199 NM_173531
ZNF100
zinc finger protein 100
chr1_-_177133950 8.164 NM_004319
NM_207108
ASTN1

astrotactin 1

chr11_+_112832201 8.102 NCAM1
neural cell adhesion molecule 1
chr5_+_140186658 8.072 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr11_-_123524881 8.065 SCN3B
sodium channel, voltage-gated, type III, beta
chr5_+_140749830 8.063 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chr10_-_123356158 7.982 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr19_-_36523770 7.956 NM_015526
CLIP3
CAP-GLY domain containing linker protein 3
chr7_-_83270746 7.953 NM_001178129
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr8_+_85095702 7.845 RALYL
RALY RNA binding protein-like
chr4_-_2263808 7.808 MXD4
MAX dimerization protein 4
chr12_-_45269953 7.807 NELL2
NEL-like 2 (chicken)
chr6_+_99872769 7.801


chr4_-_176733901 7.786 GPM6A
glycoprotein M6A
chr1_-_182360181 7.778 GLUL
glutamate-ammonia ligase
chr10_-_99393175 7.721 NM_178832
MORN4
MORN repeat containing 4
chr8_+_1952875 7.695 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr6_+_151561094 7.652 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr5_+_140220811 7.644 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr7_+_30960914 7.609 NM_001185060
NM_001185061
NM_001185062
AQP1


aquaporin 1 (Colton blood group)


chr4_+_154074269 7.602 NM_001130067
TRIM2
tripartite motif containing 2
chr7_-_37488408 7.586 ELMO1
engulfment and cell motility 1
chr8_+_79428335 7.563 NM_006823
NM_181839
PKIA

protein kinase (cAMP-dependent, catalytic) inhibitor alpha

chr17_-_37764165 7.552 NM_006160
NEUROD2
neurogenic differentiation 2
chr17_-_2996289 7.547 NM_002548
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr5_+_31799030 7.531 NM_178140
PDZD2
PDZ domain containing 2
chr10_-_62149487 7.447 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr4_-_186732208 7.363 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr5_-_42811959 7.313 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr18_-_53257033 7.313 NM_001243227
NM_001243228
TCF4

transcription factor 4

chr4_-_2263706 7.306 NM_006454
MXD4
MAX dimerization protein 4
chr6_-_112080284 7.298 NM_153048
FYN
FYN oncogene related to SRC, FGR, YES
chrX_+_110339374 7.287 NM_002578
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chr4_+_113739203 7.262 NM_001127493
ANK2
ankyrin 2, neuronal
chr22_+_19711065 7.256 NM_000407
GP1BB
glycoprotein Ib (platelet), beta polypeptide
chr7_-_99145988 7.089 FAM200A
family with sequence similarity 200, member A
chrX_-_48693934 7.075 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr1_+_2005424 7.056 NM_001242874
PRKCZ
protein kinase C, zeta
chr14_+_35514112 6.983 NM_001079519
FAM177A1
family with sequence similarity 177, member A1
chr18_+_56530060 6.933 NM_018181
ZNF532
zinc finger protein 532
chr20_+_34556528 6.924 NM_001207076
NM_080834
C20orf152

chromosome 20 open reading frame 152

chr17_+_36861398 6.916 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr12_+_32654976 6.897 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr12_-_6233684 6.893 NM_000552
VWF
von Willebrand factor
chr1_-_31345361 6.859 SDC3
syndecan 3
chr11_-_76155704 6.838


chr5_+_161275897 6.828 NM_001127646
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr17_-_9939873 6.798 GAS7
growth arrest-specific 7
chr5_-_997408 6.759 NM_001242737
LOC100506688
uncharacterized LOC100506688
chr2_-_86565205 6.672 NM_001164730
REEP1
receptor accessory protein 1
chr4_+_110749149 6.627 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.28 1.50e-11 GO:0032501 multicellular organismal process
1.34 1.92e-10 GO:0023052 signaling
1.87 2.31e-10 GO:0007155 cell adhesion
1.87 2.31e-10 GO:0022610 biological adhesion
1.31 7.00e-09 GO:0032502 developmental process
1.33 1.59e-08 GO:0007275 multicellular organismal development
1.34 5.18e-08 GO:0048856 anatomical structure development
1.52 8.54e-08 GO:0007399 nervous system development
2.26 1.33e-07 GO:0016337 cell-cell adhesion
1.35 1.49e-07 GO:0048731 system development
2.93 1.73e-07 GO:0007156 homophilic cell adhesion
1.31 3.24e-07 GO:0007165 signal transduction
1.10 6.31e-07 GO:0009987 cellular process
1.16 1.54e-06 GO:0065007 biological regulation
1.39 3.04e-06 GO:0048869 cellular developmental process
1.24 2.73e-05 GO:0051716 cellular response to stimulus
1.40 3.31e-05 GO:0007166 cell surface receptor linked signaling pathway
1.36 5.20e-05 GO:0030154 cell differentiation
1.40 5.62e-04 GO:0009653 anatomical structure morphogenesis
1.64 7.94e-04 GO:0032989 cellular component morphogenesis
1.14 9.62e-04 GO:0050794 regulation of cellular process
1.53 1.10e-03 GO:0040011 locomotion
1.13 1.35e-03 GO:0050789 regulation of biological process
1.63 2.63e-03 GO:0000902 cell morphogenesis
1.57 3.15e-03 GO:0030182 neuron differentiation
2.20 6.43e-03 GO:0001654 eye development
1.14 6.87e-03 GO:0050896 response to stimulus
1.47 8.69e-03 GO:0022008 neurogenesis
1.48 1.28e-02 GO:0048699 generation of neurons
1.46 1.36e-02 GO:0048468 cell development
1.63 1.62e-02 GO:0000904 cell morphogenesis involved in differentiation
1.59 1.79e-02 GO:0048666 neuron development
2.29 2.37e-02 GO:0043010 camera-type eye development
1.60 3.82e-02 GO:0048858 cell projection morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.35 3.03e-06 GO:0044459 plasma membrane part
1.48 5.98e-06 GO:0005887 integral to plasma membrane
1.46 1.52e-05 GO:0031226 intrinsic to plasma membrane
1.18 1.39e-03 GO:0005886 plasma membrane
1.17 4.47e-03 GO:0071944 cell periphery
1.37 1.71e-02 GO:0044421 extracellular region part
1.59 2.72e-02 GO:0044463 cell projection part
1.60 4.86e-02 GO:0031012 extracellular matrix

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.70 2.96e-06 GO:0005509 calcium ion binding
1.07 1.59e-04 GO:0005488 binding
2.88 3.03e-02 GO:0004879 ligand-dependent nuclear receptor activity