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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: TBP.p2

Z-value: 5.077

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_-_5248180	114.995	NM_000518	HBB	hemoglobin, beta
chr5_-_42811959	91.322	NM_001085486 NM_001093726 NM_005410	SEPP1	selenoprotein P, plasma, 1
chr11_+_61129831	86.796		TMEM138	transmembrane protein 138
chr12_-_15038724	82.440	NM_000900 NM_001190839	MGP	matrix Gla protein
chr1_-_59042827	81.505		TACSTD2	tumor-associated calcium signal transducer 2
chr2_-_216300770	76.550	NM_002026 NM_054034 NM_212474 NM_212476 NM_212478 NM_212482	FN1	fibronectin 1
chr7_+_142829169	74.579	NM_002652	PIP	prolactin-induced protein
chr8_-_27472188	71.693		CLU	clusterin
chr16_+_56659584	70.172	NM_175617	MT1E	metallothionein 1E
chr19_-_6720585	68.309	NM_000064	C3	complement component 3
chr16_+_56659679	67.856		MT1E	metallothionein 1E
chr7_+_94024201	60.703		COL1A2	collagen, type I, alpha 2
chr11_+_65190272	59.620
chr16_+_56685810	56.009	NM_005947	MT1B	metallothionein 1B
chr1_+_153330329	55.618	NM_002965	S100A9	S100 calcium binding protein A9
chr3_+_193853937	53.482		HES1	hairy and enhancer of split 1, (Drosophila)
chr3_+_193853930	52.832	NM_005524	HES1	hairy and enhancer of split 1, (Drosophila)
chr1_-_153029987	52.346	NM_005988	SPRR2A	small proline-rich protein 2A
chr1_-_230849863	51.828		AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr1_-_153363544	50.830	NM_002964	S100A8	S100 calcium binding protein A8
chr12_-_11463353	50.306	NM_002723	PRB4	proline-rich protein BstNI subfamily 4
chr19_-_36247917	47.546	NM_144617	HSPB6	heat shock protein, alpha-crystallin-related, B6
chr1_-_230849847	45.408		AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr21_-_28217272	44.729		ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr16_+_56716378	44.116	NM_005952	MT1X	metallothionein 1X
chr20_-_44540685	43.484		PLTP	phospholipid transfer protein
chr17_+_32582295	42.754	NM_002982	CCL2	chemokine (C-C motif) ligand 2
chr1_+_152647770	42.548	NM_178429	LCE2C	late cornified envelope 2C
chr11_-_5275904	41.223	NM_000184	HBG1 HBG2	hemoglobin, gamma A hemoglobin, gamma G
chr19_-_33793429	40.958	NM_004364	CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha
chr21_-_28217692	39.898	NM_006988	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr6_+_31783314	39.415		HSPA1A HSPA1B	heat shock 70kDa protein 1A heat shock 70kDa protein 1B
chr8_-_48650703	39.272	NM_005195	CEBPD	CCAAT/enhancer binding protein (C/EBP), delta
chr8_-_27472298	39.127	NM_001831	CLU	clusterin
chr7_+_30951414	38.844	NM_198098	AQP1	aquaporin 1 (Colton blood group)
chr9_+_130911731	38.714	NM_005564	LCN2	lipocalin 2
chr13_-_45150391	38.044		TSC22D1	TSC22 domain family, member 1
chr18_+_29171729	37.506	NM_000371	TTR	transthyretin
chr6_+_31913852	37.205		CFB	complement factor B
chr1_-_153044083	36.347	NM_001017418	SPRR2B	small proline-rich protein 2B
chr21_+_47518012	36.189	NM_001849 NM_058174 NM_058175	COL6A2	collagen, type VI, alpha 2
chr14_+_75745480	36.179	NM_005252	FOS	FBJ murine osteosarcoma viral oncogene homolog
chr6_-_52860076	36.086	NM_001512	GSTA4	glutathione S-transferase alpha 4
chr19_+_859658	36.065	NM_001928	CFD	complement factor D (adipsin)
chr8_-_24814028	34.918	NM_006158	NEFL	neurofilament, light polypeptide
chr6_-_169653922	34.685		THBS2	thrombospondin 2
chr19_-_33793441	34.663		CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha
chr11_-_2906960	34.413	NM_000076 NM_001122630 NM_001122631	CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr1_-_149858114	34.176	NM_003528	HIST2H2BE	histone cluster 2, H2be
chr12_-_52886971	33.975	NM_005554	KRT6A	keratin 6A
chr17_-_48278874	33.843		COL1A1	collagen, type I, alpha 1
chr11_-_116708334	33.806	NM_000039	APOA1	apolipoprotein A-I
chr7_+_100770378	33.550	NM_000602 NM_001165413	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr11_-_5255712	33.417	NM_000519	HBD	hemoglobin, delta
chr17_-_39780762	32.999	NM_000422	KRT17	keratin 17
chr5_-_153857782	32.818		HAND1	heart and neural crest derivatives expressed 1
chr16_+_72097124	31.970	NM_020995	HPR	haptoglobin-related protein
chr7_+_75931991	31.605		HSPB1	heat shock 27kDa protein 1
chr11_+_1718424	31.308	NM_001012416	KRTAP5-6	keratin associated protein 5-6
chr4_-_74964836	30.971		CXCL2	chemokine (C-X-C motif) ligand 2
chr12_+_52627007	30.616		KRT7	keratin 7
chr1_+_152635871	30.547	NM_178430	LCE2D	late cornified envelope 2D
chr1_-_203155827	30.261		CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)
chr11_-_18270167	29.501	NM_001199744 NM_001127380 NM_030754	SAA2-SAA4 SAA2	SAA2-SAA4 readthrough serum amyloid A2
chr9_+_124048396	29.464		GSN	gelsolin
chr12_-_53012332	29.419	NM_175068	KRT73	keratin 73
chr1_-_95007139	29.345	NM_001178096 NM_001993	F3	coagulation factor III (thromboplastin, tissue factor)
chr1_-_153013593	29.268	NM_006945	SPRR2D	small proline-rich protein 2D
chr16_+_56966025	28.854		HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr16_+_56672577	28.678	NM_005946	MT1A	metallothionein 1A
chr3_-_195310770	28.650		APOD	apolipoprotein D
chr10_-_45474210	28.591	NM_007021	C10orf10	chromosome 10 open reading frame 10
chr9_-_33447527	28.587	NM_004925	AQP3	aquaporin 3 (Gill blood group)
chr11_-_111782447	28.528	NM_001885	CRYAB	crystallin, alpha B
chr11_-_76381787	28.525	NM_001128922	LRRC32	leucine rich repeat containing 32
chr19_+_33793743	28.497		LOC80054	uncharacterized LOC80054
chr12_+_101988746	27.822	NM_002465 NM_206819 NM_206820 NM_206821	MYBPC1	myosin binding protein C, slow type
chr7_+_24323806	27.739	NM_000905	NPY	neuropeptide Y
chr7_+_75931829	27.536	NM_001540	HSPB1	heat shock 27kDa protein 1
chr16_-_15950850	27.340	NM_001040113 NM_001040114 NM_002474 NM_022844	MYH11	myosin, heavy chain 11, smooth muscle
chr17_-_61950997	27.067	NM_020991 NM_022644 NM_022645	CSH2	chorionic somatomammotropin hormone 2
chr12_-_11548485	27.056	NM_006248	PRB1 PRB2	proline-rich protein BstNI subfamily 1 proline-rich protein BstNI subfamily 2
chr9_-_104198045	26.828	NM_000035	ALDOB	aldolase B, fructose-bisphosphate
chr20_+_30193083	26.801	NM_002165 NM_181353	ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr17_-_48278987	26.644	NM_000088	COL1A1	collagen, type I, alpha 1
chr17_-_61996135	26.573	NM_000515 NM_022559 NM_022560 NM_022561 NM_022562	GH1	growth hormone 1
chr16_-_56701904	26.238	NM_005950	MT1G	metallothionein 1G
chr12_-_52867521	25.948	NM_173086	KRT6C	keratin 6C
chr11_+_18287807	25.770	NM_000331 NM_001178006 NM_199161	SAA1	serum amyloid A1
chr11_+_1151578	25.613		MUC5AC	mucin 5AC, oligomeric mucus/gel-forming
chr5_+_78407603	25.449	NM_001713	BHMT	betaine--homocysteine S-methyltransferase
chr17_-_79818406	25.391		P4HB	prolyl 4-hydroxylase, beta polypeptide
chr2_-_21266809	25.286		APOB	apolipoprotein B (including Ag(x) antigen)
chr20_-_39317875	25.196	NM_005461	MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr1_-_182360889	24.907		GLUL	glutamate-ammonia ligase
chr9_+_117085302	24.846	NM_000607	ORM1	orosomucoid 1
chr20_+_31823801	24.834	NM_001243193 NM_016583 NM_130852	BPIFA1	BPI fold containing family A, member 1
chr7_+_116593354	24.738	NM_018412 NM_021908	ST7	suppression of tumorigenicity 7
chr21_-_43735705	24.656	NM_003226	TFF3	trefoil factor 3 (intestinal)
chr17_+_38599651	24.542	NM_001552	IGFBP4	insulin-like growth factor binding protein 4
chr1_-_20306093	24.514	NM_001161729	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)
chrX_-_106960268	23.830	NM_004089	TSC22D3	TSC22 domain family, member 3
chr1_-_203155867	23.778		CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)
chr15_-_63673918	23.762		CA12	carbonic anhydrase XII
chr17_+_56315786	23.463	NM_001160102 NM_006151	LPO	lactoperoxidase
chr3_+_148545587	23.350	NM_001871	CPB1	carboxypeptidase B1 (tissue)
chrX_-_106960028	23.126		TSC22D3	TSC22 domain family, member 3
chr7_+_72742154	23.109	NM_001135211 NM_003602	FKBP6	FK506 binding protein 6, 36kDa
chr6_+_27100784	23.040	NM_021064	HIST1H2AG	histone cluster 1, H2ag
chr10_+_17851342	23.026	NM_002438	MRC1	mannose receptor, C type 1
chr20_-_43977023	23.024	NM_002999	SDC4	syndecan 4
chr1_-_203155813	22.732		CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)
chr12_+_11081833	22.626	NM_005042 NM_001110213	PRH2	proline-rich protein HaeIII subfamily 2
chr4_+_25657434	22.541	NM_001177998 NM_006424	SLC34A2	solute carrier family 34 (sodium phosphate), member 2
chr12_-_11036815	22.305	NM_006250	PRH1	proline-rich protein HaeIII subfamily 1
chr2_-_179672056	22.238	NM_003319 NM_133378 NM_133379 NM_133432 NM_133437	TTN	titin
chr3_+_49449638	22.190	NM_022171	TCTA	T-cell leukemia translocation altered gene
chr2_-_21266915	21.904	NM_000384	APOB	apolipoprotein B (including Ag(x) antigen)
chr7_+_45927958	21.762	NM_000596	IGFBP1	insulin-like growth factor binding protein 1
chr10_+_17271277	21.741		VIM	vimentin
chr17_-_61988614	21.547	NM_001318 NM_022579 NM_022580 NM_022581	CSHL1	chorionic somatomammotropin hormone-like 1
chr10_+_17271276	21.446		VIM	vimentin
chr17_-_48546174	21.424	NM_001267	CHAD	chondroadherin
chr16_+_71392615	21.382	NM_001740 NM_007088	CALB2	calbindin 2
chr17_+_32683470	21.151	NM_005408	CCL13	chemokine (C-C motif) ligand 13
chr15_-_45670624	21.137		GATM	glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr18_+_21718930	20.886	NM_012189 NM_138643 NM_153768 NM_153769 NM_153770	CABYR	calcium binding tyrosine-(Y)-phosphorylation regulated
chr4_+_71296208	20.872	NM_001145006	MUC7	mucin 7, secreted
chr1_+_37940180	20.828		ZC3H12A	zinc finger CCCH-type containing 12A
chr16_-_4292052	20.653	NM_001098814	SRL	sarcalumenin
chr15_-_51630735	20.553	NM_000103 NM_031226	CYP19A1	cytochrome P450, family 19, subfamily A, polypeptide 1
chr18_+_21719025	20.492		CABYR	calcium binding tyrosine-(Y)-phosphorylation regulated
chr14_-_103989195	20.311	NM_001823	CKB	creatine kinase, brain
chr19_+_10381763	20.078		ICAM1	intercellular adhesion molecule 1
chrX_+_46940235	19.984		RGN	regucalcin (senescence marker protein-30)
chr17_-_61973870	19.938	NM_001317	CSH1	chorionic somatomammotropin hormone 1 (placental lactogen)
chr6_+_33239798	19.904	NM_022551	RPS18	ribosomal protein S18
chr19_+_49468587	19.805		FTL	ferritin, light polypeptide
chr16_+_71392637	19.748		CALB2	calbindin 2
chr8_-_82395401	19.744	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chr17_+_32597239	19.717	NM_006273	CCL7	chemokine (C-C motif) ligand 7
chr14_+_93389491	19.677		CHGA	chromogranin A (parathyroid secretory protein 1)
chr13_+_53602829	19.551	NM_006418	OLFM4	olfactomedin 4
chr6_+_131894343	19.535	NM_000045 NM_001244438	ARG1	arginase, liver
chr4_+_74735107	19.513	NM_001511	CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr1_+_153963237	19.408	NM_001030	RPS27	ribosomal protein S27
chr8_+_133879202	19.355	NM_003235	TG	thyroglobulin
chr19_+_49468656	19.027		FTL	ferritin, light polypeptide
chr1_+_159557615	18.821	NM_001639	APCS	amyloid P component, serum
chr1_+_12916940	18.817	NM_023014	PRAMEF2	PRAME family member 2
chr1_+_152881022	18.685	NM_005547	IVL	involucrin
chr5_-_115152322	18.667	NM_001801	CDO1	cysteine dioxygenase, type I
chr18_+_56887389	18.482	NM_001012512 NM_001012513 NM_002091	GRP	gastrin-releasing peptide
chr8_+_19796840	18.377		LPL	lipoprotein lipase
chr8_+_24771276	18.348		NEFM	neurofilament, medium polypeptide
chr5_-_53606387	18.279	NM_019087	ARL15	ADP-ribosylation factor-like 15
chr7_-_45960738	18.127	NM_000598 NM_001013398	IGFBP3	insulin-like growth factor binding protein 3
chr1_+_12851545	18.076	NM_023013	PRAMEF1	PRAME family member 1
chr9_+_117092068	17.733	NM_000608	ORM2	orosomucoid 2
chr3_+_149192479	17.602		TM4SF4	transmembrane 4 L six family member 4
chr1_-_201465700	17.582	NM_001193572	CSRP1	cysteine and glycine-rich protein 1
chr1_+_86046434	17.524	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr11_+_1074869	17.367	NM_002457	MUC2	mucin 2, oligomeric mucus/gel-forming
chr1_-_228613025	17.339	NM_003493	HIST3H3	histone cluster 3, H3
chr11_+_75273245	17.093		SERPINH1	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr6_+_33239855	17.071		RPS18	ribosomal protein S18
chr2_-_163008913	16.838	NM_002054	GCG	glucagon
chr3_+_101546833	16.726	NM_001005474	NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr11_+_62186506	16.673	NM_003357	SCGB1A1	secretoglobin, family 1A, member 1 (uteroglobin)
chr19_+_35773409	16.648	NM_021175	HAMP	hepcidin antimicrobial peptide
chr21_-_43735462	16.402		TFF3	trefoil factor 3 (intestinal)
chr6_-_27806116	16.396	NM_003510	HIST1H2AK	histone cluster 1, H2ak
chr21_-_43786602	16.377	NM_003225	TFF1	trefoil factor 1
chr17_-_39661803	16.323	NM_002274 NM_153490	KRT13	keratin 13
chr20_+_42086533	16.098		SRSF6	serine/arginine-rich splicing factor 6
chr3_+_52529351	16.079	NM_015136	STAB1	stabilin 1
chr14_+_65007418	16.058		HSPA2	heat shock 70kDa protein 2
chr19_+_49468557	16.048	NM_000146	FTL	ferritin, light polypeptide
chr15_+_39873276	15.903	NM_003246	THBS1	thrombospondin 1
chr19_+_12902295	15.843	NM_002229	JUNB	jun B proto-oncogene
chr3_+_133464883	15.693	NM_001063	TF	transferrin
chr6_+_27775898	15.633	NM_003509	HIST1H2AI HIST1H2AM HIST1H3F	histone cluster 1, H2ai histone cluster 1, H2am histone cluster 1, H3f
chr8_-_6735438	15.540	NM_005218	DEFB1	defensin, beta 1
chrX_+_84498993	15.473	NM_021998	ZNF711	zinc finger protein 711
chr19_+_859673	15.447		CFD	complement factor D (adipsin)
chr11_-_6462129	15.424	NM_000613	HPX	hemopexin
chr9_-_37034358	15.089	NM_016734	PAX5	paired box 5
chr12_-_92539614	15.043	NM_001731	BTG1	B-cell translocation gene 1, anti-proliferative
chr6_-_26250832	14.771	NM_021018	HIST1H3J HIST1H3F	histone cluster 1, H3j histone cluster 1, H3f
chr20_+_3052265	14.599	NM_000915	OXT	oxytocin, prepropeptide
chr16_+_202853	14.589	NM_005332	HBZ	hemoglobin, zeta
chr4_-_140098236	14.523
chr8_+_24771268	14.326	NM_005382	NEFM	neurofilament, medium polypeptide
chr17_-_39041436	14.321	NM_019010	KRT20	keratin 20
chr1_-_11714471	13.952		FBXO2	F-box protein 2
chr6_+_12290528	13.810	NM_001168319 NM_001955	EDN1	endothelin 1
chr1_-_27481400	13.788	NM_003047	SLC9A1	solute carrier family 9 (sodium/hydrogen exchanger), member 1
chr17_+_79008945	13.756	NM_001144888 NM_006340 NM_017450 NM_017451	BAIAP2	BAI1-associated protein 2
chr16_+_56691854	13.754	NM_005949	MT1F	metallothionein 1F
chr17_-_61959160	13.649	NM_002059 NM_022556 NM_022557 NM_022558	GH2	growth hormone 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.44	4.99e-26	GO:0042221	response to chemical stimulus
2.24	2.11e-21	GO:0006950	response to stress
3.24	4.86e-17	GO:0006952	defense response
2.58	5.88e-15	GO:0010033	response to organic substance
4.98	7.92e-15	GO:0006954	inflammatory response
1.57	2.32e-14	GO:0032501	multicellular organismal process
2.20	2.36e-14	GO:0048513	organ development
4.86	1.22e-13	GO:0010035	response to inorganic substance
2.86	1.59e-13	GO:0009611	response to wounding
1.47	3.27e-13	GO:0050896	response to stimulus
1.69	1.28e-12	GO:0032502	developmental process
2.83	2.18e-12	GO:0009888	tissue development
2.01	3.87e-12	GO:0065008	regulation of biological quality
2.71	4.15e-12	GO:0070887	cellular response to chemical stimulus
8.07	4.39e-12	GO:0006334	nucleosome assembly
1.77	6.02e-12	GO:0048856	anatomical structure development
7.66	1.53e-11	GO:0031497	chromatin assembly
7.28	4.92e-11	GO:0034728	nucleosome organization
7.01	1.19e-10	GO:0065004	protein-DNA complex assembly
1.78	1.64e-10	GO:0048731	system development
3.29	3.52e-10	GO:0009607	response to biotic stimulus
4.46	4.10e-10	GO:0009617	response to bacterium
6.63	4.15e-10	GO:0071824	protein-DNA complex subunit organization
1.66	5.96e-10	GO:0007275	multicellular organismal development
6.10	8.51e-10	GO:0006323	DNA packaging
2.56	1.74e-09	GO:0051704	multi-organism process
3.49	1.95e-09	GO:0051707	response to other organism
2.24	2.17e-09	GO:0051239	regulation of multicellular organismal process
7.26	2.63e-09	GO:0000302	response to reactive oxygen species
2.92	5.55e-09	GO:0009725	response to hormone stimulus
3.32	5.77e-09	GO:0051094	positive regulation of developmental process
2.48	1.01e-08	GO:0050793	regulation of developmental process
10.76	1.88e-08	GO:0034614	cellular response to reactive oxygen species
5.50	2.50e-08	GO:0006333	chromatin assembly or disassembly
5.24	2.65e-08	GO:0071103	DNA conformation change
2.83	2.86e-08	GO:0048878	chemical homeostasis
8.61	2.88e-08	GO:0034599	cellular response to oxidative stress
2.71	5.09e-08	GO:0009719	response to endogenous stimulus
4.64	6.26e-08	GO:0006979	response to oxidative stress
2.44	6.77e-08	GO:0042592	homeostatic process
7.95	1.09e-07	GO:0042542	response to hydrogen peroxide
2.56	1.15e-07	GO:0006955	immune response
4.42	1.89e-07	GO:0008544	epidermis development
2.61	2.07e-07	GO:0002682	regulation of immune system process
2.31	2.72e-07	GO:0042127	regulation of cell proliferation
3.80	3.10e-07	GO:0048545	response to steroid hormone stimulus
12.69	4.19e-07	GO:0070301	cellular response to hydrogen peroxide
1.66	4.99e-07	GO:0048518	positive regulation of biological process
2.09	7.79e-07	GO:0002376	immune system process
8.37	8.32e-07	GO:0002526	acute inflammatory response
2.25	8.95e-07	GO:0009605	response to external stimulus
5.59	3.34e-06	GO:0008217	regulation of blood pressure
2.62	3.77e-06	GO:0009887	organ morphogenesis
3.85	3.95e-06	GO:0032101	regulation of response to external stimulus
2.38	7.34e-06	GO:2000026	regulation of multicellular organismal development
2.25	1.28e-05	GO:0040011	locomotion
2.26	1.45e-05	GO:0043933	macromolecular complex subunit organization
3.07	1.71e-05	GO:0034622	cellular macromolecular complex assembly
4.55	1.72e-05	GO:0002237	response to molecule of bacterial origin
2.74	2.42e-05	GO:0009628	response to abiotic stimulus
12.11	3.15e-05	GO:0042743	hydrogen peroxide metabolic process
2.57	3.58e-05	GO:0006928	cellular component movement
4.14	4.10e-05	GO:0010038	response to metal ion
1.24	4.70e-05	GO:0065007	biological regulation
3.07	5.06e-05	GO:0051240	positive regulation of multicellular organismal process
2.66	5.25e-05	GO:0034621	cellular macromolecular complex subunit organization
1.61	6.39e-05	GO:0048522	positive regulation of cellular process
3.32	8.96e-05	GO:0006875	cellular metal ion homeostasis
3.04	1.04e-04	GO:0045597	positive regulation of cell differentiation
1.41	1.45e-04	GO:0051716	cellular response to stimulus
1.81	1.54e-04	GO:0009653	anatomical structure morphogenesis
2.62	1.81e-04	GO:0072358	cardiovascular system development
2.62	1.81e-04	GO:0072359	circulatory system development
3.21	1.82e-04	GO:0055065	metal ion homeostasis
4.46	3.00e-04	GO:0051789	response to protein stimulus
5.05	3.15e-04	GO:0009266	response to temperature stimulus
2.24	3.83e-04	GO:0065003	macromolecular complex assembly
8.07	3.99e-04	GO:0072593	reactive oxygen species metabolic process
3.61	4.43e-04	GO:0003013	circulatory system process
3.61	4.43e-04	GO:0008015	blood circulation
4.07	5.48e-04	GO:0042445	hormone metabolic process
4.26	6.04e-04	GO:0032496	response to lipopolysaccharide
3.01	6.30e-04	GO:0030003	cellular cation homeostasis
7.69	6.57e-04	GO:0031424	keratinization
7.69	6.57e-04	GO:0045639	positive regulation of myeloid cell differentiation
12.56	9.92e-04	GO:0042744	hydrogen peroxide catabolic process
2.21	1.04e-03	GO:0045595	regulation of cell differentiation
2.85	1.11e-03	GO:0055080	cation homeostasis
4.57	1.19e-03	GO:0050727	regulation of inflammatory response
3.25	1.45e-03	GO:0008202	steroid metabolic process
2.53	1.49e-03	GO:0055082	cellular chemical homeostasis
3.03	1.61e-03	GO:0001817	regulation of cytokine production
2.35	1.66e-03	GO:0019725	cellular homeostasis
3.46	1.73e-03	GO:0010817	regulation of hormone levels
5.12	1.79e-03	GO:0045637	regulation of myeloid cell differentiation
1.54	1.83e-03	GO:0048519	negative regulation of biological process
3.57	1.98e-03	GO:0003012	muscle system process
7.86	2.12e-03	GO:0030049	muscle filament sliding
7.86	2.12e-03	GO:0033275	actin-myosin filament sliding
3.68	2.44e-03	GO:0006936	muscle contraction
20.18	2.47e-03	GO:0042738	exogenous drug catabolic process
6.73	2.49e-03	GO:0045766	positive regulation of angiogenesis
1.80	2.56e-03	GO:0009893	positive regulation of metabolic process
3.51	2.58e-03	GO:0030855	epithelial cell differentiation
7.65	2.71e-03	GO:0070252	actin-mediated cell contraction
2.55	2.77e-03	GO:0016477	cell migration
2.85	2.86e-03	GO:0034097	response to cytokine stimulus
13.84	3.44e-03	GO:0071347	cellular response to interleukin-1
2.35	3.45e-03	GO:0006935	chemotaxis
2.35	3.45e-03	GO:0042330	taxis
2.89	3.66e-03	GO:0040012	regulation of locomotion
5.24	3.68e-03	GO:0009913	epidermal cell differentiation
3.06	3.84e-03	GO:0051241	negative regulation of multicellular organismal process
1.87	3.87e-03	GO:0022607	cellular component assembly
2.61	4.08e-03	GO:0060429	epithelium development
2.46	4.14e-03	GO:0002684	positive regulation of immune system process
3.71	4.29e-03	GO:0050900	leukocyte migration
2.33	4.38e-03	GO:0008284	positive regulation of cell proliferation
6.33	4.48e-03	GO:0030048	actin filament-based movement
1.57	4.54e-03	GO:0030154	cell differentiation
4.72	4.66e-03	GO:0001818	negative regulation of cytokine production
2.85	4.75e-03	GO:0042493	response to drug
2.69	5.26e-03	GO:0043434	response to peptide hormone stimulus
2.06	5.35e-03	GO:0071844	cellular component assembly at cellular level
5.55	5.49e-03	GO:0030216	keratinocyte differentiation
2.74	6.07e-03	GO:0009991	response to extracellular stimulus
2.45	6.11e-03	GO:0006873	cellular ion homeostasis
2.40	6.83e-03	GO:0048870	cell motility
2.40	6.83e-03	GO:0051674	localization of cell
2.00	6.87e-03	GO:0048584	positive regulation of response to stimulus
2.94	7.69e-03	GO:0030334	regulation of cell migration
1.55	7.71e-03	GO:0048869	cellular developmental process
5.98	7.75e-03	GO:0051591	response to cAMP
2.68	8.69e-03	GO:0031347	regulation of defense response
4.47	8.71e-03	GO:0007586	digestion
7.83	8.78e-03	GO:0070555	response to interleukin-1
3.91	8.93e-03	GO:0031960	response to corticosteroid stimulus
1.11	8.94e-03	GO:0009987	cellular process
2.90	9.40e-03	GO:2000145	regulation of cell motility
4.42	9.83e-03	GO:0045765	regulation of angiogenesis
2.17	1.04e-02	GO:0042060	wound healing
16.15	1.06e-02	GO:0001542	ovulation from ovarian follicle
16.15	1.06e-02	GO:0042737	drug catabolic process
16.15	1.06e-02	GO:0045672	positive regulation of osteoclast differentiation
4.37	1.11e-02	GO:0032103	positive regulation of response to external stimulus
2.34	1.11e-02	GO:0050801	ion homeostasis
9.04	1.25e-02	GO:0002763	positive regulation of myeloid leukocyte differentiation
1.75	1.53e-02	GO:0031325	positive regulation of cellular metabolic process
2.72	1.66e-02	GO:0031667	response to nutrient levels
3.93	1.72e-02	GO:0051384	response to glucocorticoid stimulus
3.90	1.91e-02	GO:0042742	defense response to bacterium
5.38	2.08e-02	GO:0033500	carbohydrate homeostasis
5.38	2.08e-02	GO:0042593	glucose homeostasis
8.37	2.19e-02	GO:0031032	actomyosin structure organization
6.98	2.20e-02	GO:0006953	acute-phase response
3.62	2.33e-02	GO:0009410	response to xenobiotic stimulus
5.93	2.55e-02	GO:0055002	striated muscle cell development
1.73	2.61e-02	GO:0044085	cellular component biogenesis
4.74	2.69e-02	GO:0002576	platelet degranulation
1.74	2.70e-02	GO:0010604	positive regulation of macromolecule metabolic process
8.07	2.85e-02	GO:0032963	collagen metabolic process
3.33	3.37e-02	GO:0070482	response to oxygen levels
9.69	3.81e-02	GO:0045103	intermediate filament-based process
2.73	4.02e-02	GO:0001568	blood vessel development
2.64	4.14e-02	GO:0051270	regulation of cellular component movement
4.97	4.32e-02	GO:0019748	secondary metabolic process
7.54	4.65e-02	GO:0044259	multicellular organismal macromolecule metabolic process
4.12	4.66e-02	GO:0030198	extracellular matrix organization
6.30	4.90e-02	GO:0006721	terpenoid metabolic process
3.59	4.94e-02	GO:0043627	response to estrogen stimulus

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
2.95	2.13e-42	GO:0005576	extracellular region
4.64	1.35e-41	GO:0005615	extracellular space
4.00	2.03e-40	GO:0044421	extracellular region part
12.38	1.02e-17	GO:0000786	nucleosome
7.82	1.08e-12	GO:0032993	protein-DNA complex
5.54	4.75e-12	GO:0005882	intermediate filament
4.80	2.10e-10	GO:0045111	intermediate filament cytoskeleton
3.79	3.14e-07	GO:0000785	chromatin
3.55	3.44e-05	GO:0030141	stored secretory granule
6.83	7.08e-05	GO:0031983	vesicle lumen
2.69	1.09e-04	GO:0031012	extracellular matrix
12.56	1.14e-04	GO:0032982	myosin filament
4.20	1.85e-04	GO:0043292	contractile fiber
4.18	4.41e-04	GO:0030016	myofibril
4.73	1.28e-03	GO:0045095	keratin filament
4.00	1.61e-03	GO:0044449	contractile fiber part
1.43	2.09e-03	GO:0043228	non-membrane-bounded organelle
1.43	2.09e-03	GO:0043232	intracellular non-membrane-bounded organelle
10.76	2.21e-03	GO:0005859	muscle myosin complex
6.06	2.45e-03	GO:0034774	secretory granule lumen
5.81	3.47e-03	GO:0060205	cytoplasmic membrane-bounded vesicle lumen
13.46	3.63e-03	GO:0005833	hemoglobin complex
1.75	3.91e-03	GO:0044430	cytoskeletal part
9.69	4.38e-03	GO:0016460	myosin II complex
9.23	5.98e-03	GO:0001533	cornified envelope
1.57	7.17e-03	GO:0005856	cytoskeleton
2.13	1.39e-02	GO:0044427	chromosomal part
5.50	1.58e-02	GO:0031093	platelet alpha granule lumen
4.54	2.64e-02	GO:0016459	myosin complex
2.32	3.25e-02	GO:0005578	proteinaceous extracellular matrix

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
3.65	4.29e-18	GO:0005198	structural molecule activity
2.81	2.25e-16	GO:0005102	receptor binding
8.81	2.29e-16	GO:0005179	hormone activity
5.16	6.78e-12	GO:0005125	cytokine activity
1.17	1.28e-10	GO:0005488	binding
5.92	2.99e-10	GO:0046906	tetrapyrrole binding
6.04	5.75e-10	GO:0020037	heme binding
4.37	8.12e-09	GO:0005506	iron ion binding
9.83	1.32e-08	GO:0008009	chemokine activity
4.49	5.46e-08	GO:0005126	cytokine receptor binding
8.87	6.22e-08	GO:0042379	chemokine receptor binding
9.33	1.39e-07	GO:0019825	oxygen binding
1.28	3.20e-07	GO:0005515	protein binding
4.32	6.36e-07	GO:0001664	G-protein-coupled receptor binding
5.65	3.28e-05	GO:0004497	monooxygenase activity
5.91	5.43e-05	GO:0005200	structural constituent of cytoskeleton
13.30	1.08e-04	GO:0005212	structural constituent of eye lens
7.51	1.44e-04	GO:0008307	structural constituent of muscle
2.66	2.06e-04	GO:0030246	carbohydrate binding
4.01	2.49e-04	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
14.90	3.49e-04	GO:0005344	oxygen transporter activity
4.37	3.75e-04	GO:0008201	heparin binding
3.66	4.62e-04	GO:0001871	pattern binding
3.66	4.62e-04	GO:0030247	polysaccharide binding
25.83	1.35e-03	GO:0046870	cadmium ion binding
9.42	1.60e-03	GO:0070330	aromatase activity
3.45	1.99e-03	GO:0008083	growth factor activity
8.70	2.88e-03	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
3.52	2.97e-03	GO:0005539	glycosaminoglycan binding
4.44	8.69e-03	GO:0005201	extracellular matrix structural constituent
11.53	1.31e-02	GO:0004089	carbonate dehydratase activity
5.87	1.45e-02	GO:0043498	cell surface binding
3.04	1.82e-02	GO:0009055	electron carrier activity
6.65	1.91e-02	GO:0004601	peroxidase activity
6.65	1.91e-02	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor
10.09	2.73e-02	GO:0008395	steroid hydroxylase activity
24.22	3.65e-02	GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
24.22	3.65e-02	GO:0034875	caffeine oxidase activity
5.07	4.34e-02	GO:0016209	antioxidant activity