Motif ID: TBX4,5.p2

Z-value: 2.557


Transcription factors associated with TBX4,5.p2:

Gene SymbolEntrez IDGene Name
TBX4 9496 T-box 4
TBX5 6910 T-box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TBX5chr12_-_1148417020.665.5e-29Click!
TBX4chr17_+_595338060.572.3e-20Click!


Activity profile for motif TBX4,5.p2.

activity profile for motif TBX4,5.p2


Sorted Z-values histogram for motif TBX4,5.p2

Sorted Z-values for motif TBX4,5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBX4,5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_44581045 35.829 CASC4
cancer susceptibility candidate 4
chr15_+_74421986 32.746 NM_001130137
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr3_+_167453431 29.133 NM_001122752
NM_005025
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr9_+_139872014 28.805 PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr15_+_74421698 28.790 NM_001130136
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr12_-_45270071 27.480 NELL2
NEL-like 2 (chicken)
chr1_+_156698270 25.018 RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr1_-_156399183 24.476 NM_006365
C1orf61
chromosome 1 open reading frame 61
chr15_+_44580954 24.113 CASC4
cancer susceptibility candidate 4
chr14_+_95078713 23.540 NM_001085
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr12_+_66218879 23.422 HMGA2
high mobility group AT-hook 2
chr15_+_44580870 23.203 NM_138423
NM_177974
CASC4

cancer susceptibility candidate 4

chrX_+_75392763 23.112 NM_016500
CXorf26
chromosome X open reading frame 26
chr16_+_22825481 22.268 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chrX_+_101906293 21.641 NM_001099410
NM_001099411
NM_014710
NM_001184727
GPRASP1



G protein-coupled receptor associated sorting protein 1



chr11_+_71791376 21.375 NM_001145307
NM_001145308
NM_001205138
NM_145309
LRTOMT



leucine rich transmembrane and 0-methyltransferase domain containing



chrY_+_15016698 20.161 NM_004660
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr1_+_156698250 20.005 NM_001142560
NM_015997
RRNAD1

ribosomal RNA adenine dimethylase domain containing 1

chr5_-_131132642 19.992 FNIP1
folliculin interacting protein 1
chr12_-_45270157 19.500 NM_001145108
NM_006159
NELL2

NEL-like 2 (chicken)

chr8_+_21912327 18.817 NM_001114136
NM_001114139
EPB49

erythrocyte membrane protein band 4.9 (dematin)

chr12_-_91576579 18.734 DCN
decorin
chr12_-_45269953 18.234 NELL2
NEL-like 2 (chicken)
chr12_-_6798528 18.149 NM_133476
ZNF384
zinc finger protein 384
chr22_+_23229959 18.092 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr1_+_16062808 18.051 NM_207348
SLC25A34
solute carrier family 25, member 34
chr15_-_77197743 17.838 SCAPER
S-phase cyclin A-associated protein in the ER
chr5_-_42811959 17.650 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr4_-_8160435 17.013 NM_001130083
NM_001130084
NM_001130085
NM_001130086
NM_001130087
NM_001130088
NM_032432
ABLIM2






actin binding LIM protein family, member 2






chr2_-_175869910 16.874 NM_001822
NM_001025201
CHN1

chimerin (chimaerin) 1

chr7_-_111846384 16.872 NM_014705
DOCK4
dedicator of cytokinesis 4
chr2_-_89165652 16.544


chr17_-_42580745 16.257 GPATCH8
G patch domain containing 8
chr17_+_28256873 16.228 NM_001145053
EFCAB5
EF-hand calcium binding domain 5
chr20_-_4804067 16.154 NM_014737
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr7_-_994008 16.072 ADAP1
ArfGAP with dual PH domains 1
chr10_-_46970595 15.873 NM_031912
NM_181519
SYT15

synaptotagmin XV

chr2_-_145090028 15.803 GTDC1
glycosyltransferase-like domain containing 1
chr19_-_36247917 15.801 NM_144617
HSPB6
heat shock protein, alpha-crystallin-related, B6
chr11_+_73358593 15.733 NM_001130034
NM_001130035
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr9_-_123837410 15.722 C5
complement component 5
chr5_-_130970851 15.694 RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6
chr7_-_994259 15.496 NM_006869
ADAP1
ArfGAP with dual PH domains 1
chr7_+_135347211 15.232 NM_001130929
SLC13A4
C7orf73
solute carrier family 13 (sodium/sulfate symporters), member 4
chromosome 7 open reading frame 73
chr4_-_44728518 14.761 NM_138335
GNPDA2
glucosamine-6-phosphate deaminase 2
chr5_-_130970907 14.629 NM_001164386
NM_001164387
NM_001164388
NM_001164389
NM_001164390
NM_016340
RAPGEF6





Rap guanine nucleotide exchange factor (GEF) 6





chr19_-_39390168 14.533 NM_012237
NM_001193286
NM_030593
SIRT2


sirtuin 2


chr5_-_108745569 14.410 NM_014819
PJA2
praja ring finger 2
chr12_-_91576805 14.145 NM_001920
DCN
decorin
chr3_+_133465098 14.118 TF
transferrin
chr1_+_38022514 14.040 NM_003462
DNALI1
dynein, axonemal, light intermediate chain 1
chr7_+_29234111 14.030 NM_004067
CHN2
chimerin (chimaerin) 2
chr7_-_100026284 13.867 NM_017984
ZCWPW1
zinc finger, CW type with PWWP domain 1
chr14_-_107113943 13.825 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr2_+_230787195 13.660 NM_174899
FBXO36
F-box protein 36
chr16_+_2587989 13.537 PDPK1
3-phosphoinositide dependent protein kinase-1
chr7_+_29234325 13.364 CHN2
chimerin (chimaerin) 2
chr19_+_507475 13.341 NM_033513
TPGS1
tubulin polyglutamylase complex subunit 1
chr16_+_24267474 13.313 CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr12_-_56211503 13.296 SARNP
SAP domain containing ribonucleoprotein
chr4_-_4249928 12.999 NM_032927
TMEM128
transmembrane protein 128
chr6_+_31982538 12.736 NM_001242823
NM_001252204
NM_007293
NM_001002029
LOC100293534
C4A

C4B
complement C4-B-like
complement component 4A (Rodgers blood group)

complement component 4B (Chido blood group)
chr22_-_51016343 12.556 NM_001145137
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr2_-_65454716 12.492 LOC729324
hCG1986447
chrX_+_153237990 12.489 NM_003492
TMEM187
transmembrane protein 187
chr7_+_87257704 12.456 NM_001134405
NM_001134406
NM_138290
RUNDC3B


RUN domain containing 3B


chr2_-_152955810 12.432 CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chrY_+_15016018 12.338 NM_001122665
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr17_+_34431219 12.307 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr16_+_24267672 12.268 CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr11_-_695010 12.197 DEAF1
deformed epidermal autoregulatory factor 1 (Drosophila)
chr12_-_48152180 12.141 NM_001098532
NM_006105
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr19_+_50879681 12.132 NM_007121
NR1H2
nuclear receptor subfamily 1, group H, member 2
chr5_-_134914968 12.129 NM_004887
CXCL14
chemokine (C-X-C motif) ligand 14
chr7_+_86274076 12.014 GRM3
glutamate receptor, metabotropic 3
chr11_+_46722564 11.965 NM_001184751
ZNF408
zinc finger protein 408
chrX_+_69642880 11.896 NM_001171191
NM_001171192
NM_001171193
NM_017711
GDPD2



glycerophosphodiester phosphodiesterase domain containing 2



chr1_-_178062734 11.818 LOC100302401
uncharacterized LOC100302401
chr3_-_179169330 11.818 NM_021629
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr9_+_140032774 11.758 GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr18_+_23806385 11.726 NM_005640
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr19_+_35521591 11.691 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr2_+_170590454 11.683 KLHL23
kelch-like 23 (Drosophila)
chr12_-_45270632 11.627 NM_001145107
NELL2
NEL-like 2 (chicken)
chr11_-_236833 11.548 SIRT3
sirtuin 3
chr2_-_145090038 11.545 NM_001164629
GTDC1
glycosyltransferase-like domain containing 1
chr7_+_30951414 11.444 NM_198098
AQP1
aquaporin 1 (Colton blood group)
chr17_-_7123368 11.437 NM_001365
DLG4
discs, large homolog 4 (Drosophila)
chr2_-_237172987 11.404 NM_212556
ASB18
ankyrin repeat and SOCS box containing 18
chr10_-_93392857 11.320 NM_005398
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr18_+_11981457 11.318 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr16_+_2588000 11.280 PDPK1
3-phosphoinositide dependent protein kinase-1
chr10_-_93392744 11.264 PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr19_-_9731883 11.262 NM_152289
ZNF561
zinc finger protein 561
chr6_-_28303910 11.235 NM_001135216
NM_001243243
ZNF323

zinc finger protein 323

chrX_+_102470003 11.216 NM_001080425
NM_001127688
BEX4

brain expressed, X-linked 4

chr12_+_51318743 10.983 METTL7A
methyltransferase like 7A
chr22_-_51016845 10.974 NM_004377
NM_152246
NM_001145134
NM_001145135
NM_001145136
NM_152245
CPT1B





carnitine palmitoyltransferase 1B (muscle)





chr10_+_114135013 10.950 NM_203380
ACSL5
acyl-CoA synthetase long-chain family member 5
chr11_-_695069 10.708 DEAF1
deformed epidermal autoregulatory factor 1 (Drosophila)
chr18_+_55102777 10.669 NM_004852
ONECUT2
one cut homeobox 2
chr1_-_241520384 10.615 RGS7
regulator of G-protein signaling 7
chr6_+_31949800 10.609 NM_001242823
NM_001252204
NM_007293
NM_001002029
LOC100293534
C4A

C4B
complement C4-B-like
complement component 4A (Rodgers blood group)

complement component 4B (Chido blood group)
chr19_-_54327428 10.528 NM_144687
NLRP12
NLR family, pyrin domain containing 12
chr19_-_46295647 10.516 DMWD
dystrophia myotonica, WD repeat containing
chr1_-_11907741 10.510 NM_006172
NPPA
natriuretic peptide A
chr19_-_39108534 10.505 NM_001042600
NM_007181
MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1

chr7_+_100612689 10.489


chr3_+_133465204 10.485 TF
transferrin
chr19_+_38755097 10.444 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr19_-_36499583 10.441 NM_001039876
C19orf46
chromosome 19 open reading frame 46
chr5_+_54320083 10.384 NM_002104
GZMK
granzyme K (granzyme 3; tryptase II)
chr2_-_73053030 10.304 NM_015189
EXOC6B
exocyst complex component 6B
chr2_+_61108702 10.297 REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr1_+_151584514 10.288 NM_030918
SNX27
sorting nexin family member 27
chrX_+_8432870 10.218 NM_001001888
VCX3B
VCX3A
variable charge, X-linked 3B
variable charge, X-linked 3A
chr19_+_7828034 10.212 NM_001144904
NM_001144905
NM_001144906
NM_001144907
NM_001144908
NM_001144909
NM_001144910
NM_001144911
NM_014257
CLEC4M








C-type lectin domain family 4, member M








chr3_+_133464883 10.209 NM_001063
TF
transferrin
chr1_+_44412418 10.189 NM_014652
IPO13
importin 13
chr19_+_49838700 10.176 CD37
CD37 molecule
chr16_+_31271277 10.148 NM_000632
NM_001145808
ITGAM

integrin, alpha M (complement component 3 receptor 3 subunit)

chr1_-_241520467 10.029 NM_002924
RGS7
regulator of G-protein signaling 7
chr19_+_49838734 10.005 CD37
CD37 molecule
chr6_-_84937313 9.994 NM_014895
KIAA1009
KIAA1009
chr12_+_79258794 9.907 SYT1
synaptotagmin I
chr2_+_61108724 9.905 NM_002908
REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr17_+_30814708 9.901


chr3_-_133748828 9.813 NM_005630
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr8_-_27101240 9.806 STMN4
stathmin-like 4
chr1_+_118148506 9.781 NM_017709
FAM46C
family with sequence similarity 46, member C
chr16_+_31271311 9.775 ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr11_-_75236418 9.767 NM_030792
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr11_-_64490654 9.753 NM_015080
NM_138732
NRXN2

neurexin 2

chr7_-_103629962 9.746 NM_005045
NM_173054
RELN

reelin

chr12_+_51818592 9.728 NM_001039960
NM_004858
SLC4A8

solute carrier family 4, sodium bicarbonate cotransporter, member 8

chrX_-_70331297 9.636 NM_000206
IL2RG
interleukin 2 receptor, gamma
chr19_+_38755238 9.632 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr16_+_50776012 9.609 NM_001042412
CYLD
cylindromatosis (turban tumor syndrome)
chr16_+_2588021 9.578 PDPK1
3-phosphoinositide dependent protein kinase-1
chr10_-_100206643 9.546 HPS1
Hermansky-Pudlak syndrome 1
chr11_-_59383616 9.529 NM_002556
OSBP
oxysterol binding protein
chr21_+_34398210 9.509 NM_005806
OLIG2
oligodendrocyte lineage transcription factor 2
chr11_-_46722139 9.509 ARHGAP1
Rho GTPase activating protein 1
chr1_+_17846818 9.501 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr6_-_159420796 9.488 RSPH3
radial spoke 3 homolog (Chlamydomonas)
chr9_+_74526527 9.484 C9orf85
chromosome 9 open reading frame 85
chr4_-_99579540 9.483 NM_005723
TSPAN5
tetraspanin 5
chr2_+_176972005 9.433 NM_021192
HOXD11
homeobox D11
chr10_-_99393175 9.422 NM_178832
MORN4
MORN repeat containing 4
chr12_+_51818669 9.411 SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr11_-_129062092 9.385 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chrX_-_48693934 9.367 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr11_+_46958228 9.345 NM_001003676
NM_001003677
NM_001003678
NM_024113
C11orf49



chromosome 11 open reading frame 49



chr11_+_125774271 9.289 NM_013264
DDX25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr1_+_35225341 9.273 NM_153212
GJB4
gap junction protein, beta 4, 30.3kDa
chr1_+_118148668 9.236 FAM46C
family with sequence similarity 46, member C
chr19_+_50706868 9.221 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr11_+_1889902 9.181 NM_001013253
LSP1
lymphocyte-specific protein 1
chr10_+_135192694 9.159 NM_152911
NM_207127
NM_207128
PAOX


polyamine oxidase (exo-N4-amino)


chr13_-_45150391 9.105 TSC22D1
TSC22 domain family, member 1
chr10_-_99531712 9.075 NM_003015
SFRP5
secreted frizzled-related protein 5
chr11_+_46722316 9.048 NM_024741
ZNF408
zinc finger protein 408
chr5_-_39203061 9.030 FYB
FYN binding protein
chr14_-_107013474 9.027 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr12_-_6579754 9.010 NM_014231
NM_016830
NM_199245
VAMP1


vesicle-associated membrane protein 1 (synaptobrevin 1)


chr19_-_5622794 8.919 NM_014649
SAFB2
scaffold attachment factor B2
chr3_-_133748727 8.900 SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr17_+_14204326 8.900 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr1_+_156589085 8.815 NM_021817
HAPLN2
hyaluronan and proteoglycan link protein 2
chr2_+_242127923 8.800 NM_001001666
NM_001001891
ANO7

anoctamin 7

chr19_+_49838673 8.792 NM_001040031
NM_001774
CD37

CD37 molecule

chr9_+_124048869 8.760 GSN
gelsolin
chr14_-_105886075 8.753 LOC100507437
uncharacterized LOC100507437
chr1_-_156786500 8.723 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr15_+_68871285 8.714 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr19_+_2096930 8.664 IZUMO4
IZUMO family member 4
chr6_-_6320875 8.656 F13A1
coagulation factor XIII, A1 polypeptide
chr1_-_202129118 8.634 NM_080588
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr10_-_100206698 8.605 NM_000195
NM_182639
HPS1

Hermansky-Pudlak syndrome 1

chr1_-_169862982 8.580 SCYL3
SCY1-like 3 (S. cerevisiae)
chr5_-_134914447 8.566 CXCL14
chemokine (C-X-C motif) ligand 14
chr7_-_6312137 8.562 NM_004227
CYTH3
cytohesin 3
chr12_+_69742130 8.517 NM_000239
LYZ
lysozyme
chr11_+_61197574 8.489 NM_017841
SDHAF2
succinate dehydrogenase complex assembly factor 2
chr19_+_39833132 8.485 SAMD4B
sterile alpha motif domain containing 4B
chr1_-_85725315 8.436 NM_198077
C1orf52
chromosome 1 open reading frame 52
chr19_-_57183122 8.434 NM_001005850
ZNF835
zinc finger protein 835
chr8_+_21915371 8.401 NM_001114135
EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr17_-_39968823 8.399 LEPREL4
leprecan-like 4
chr7_-_37025696 8.353 ELMO1
engulfment and cell motility 1
chr9_+_72873985 8.342 SMC5
structural maintenance of chromosomes 5
chr9_-_136024522 8.336 NM_001042368
RALGDS
ral guanine nucleotide dissociation stimulator
chr5_-_149669400 8.294 NM_015981
NM_171825
CAMK2A

calcium/calmodulin-dependent protein kinase II alpha

chr16_+_50775960 8.292 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr9_-_35115844 8.286 NM_025182
FAM214B
family with sequence similarity 214, member B
chr11_-_71791734 8.279 NUMA1
nuclear mitotic apparatus protein 1
chr11_-_33891258 8.278 LMO2
LIM domain only 2 (rhombotin-like 1)
chr4_-_57547845 8.244 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr12_+_69742140 8.226 LYZ
lysozyme
chr15_-_65412175 8.222 PDCD7
programmed cell death 7

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.24 3.92e-18 GO:0065007 biological regulation
1.42 8.15e-18 GO:0023052 signaling
1.23 2.03e-14 GO:0050789 regulation of biological process
1.13 1.43e-12 GO:0009987 cellular process
1.23 1.53e-12 GO:0050794 regulation of cellular process
1.86 8.18e-11 GO:0007267 cell-cell signaling
1.71 5.87e-10 GO:0007154 cell communication
1.33 3.89e-09 GO:0007165 signal transduction
1.21 1.45e-08 GO:0050896 response to stimulus
1.24 2.13e-08 GO:0032501 multicellular organismal process
1.28 3.08e-08 GO:0051716 cellular response to stimulus
1.54 1.68e-07 GO:0051239 regulation of multicellular organismal process
1.28 2.20e-07 GO:0032502 developmental process
1.42 5.92e-07 GO:0048583 regulation of response to stimulus
1.31 7.20e-07 GO:0048856 anatomical structure development
1.38 3.45e-06 GO:0048869 cellular developmental process
1.38 8.80e-06 GO:0030154 cell differentiation
1.61 9.52e-06 GO:0040011 locomotion
1.83 1.06e-05 GO:0019226 transmission of nerve impulse
1.83 1.06e-05 GO:0035637 multicellular organismal signaling
1.49 2.16e-05 GO:0002376 immune system process
1.61 1.08e-04 GO:0006955 immune response
1.41 2.52e-04 GO:0007399 nervous system development
1.24 2.59e-04 GO:0007275 multicellular organismal development
1.27 3.43e-04 GO:0048731 system development
1.72 3.70e-04 GO:0006935 chemotaxis
1.72 3.70e-04 GO:0042330 taxis
1.31 5.12e-04 GO:0042221 response to chemical stimulus
1.51 6.61e-04 GO:0048468 cell development
1.75 1.07e-03 GO:0007268 synaptic transmission
1.39 1.18e-03 GO:0009966 regulation of signal transduction
1.73 1.93e-03 GO:0032583 regulation of gene-specific transcription
1.57 2.63e-03 GO:0010628 positive regulation of gene expression
1.46 3.00e-03 GO:0009605 response to external stimulus
1.48 3.11e-03 GO:0009611 response to wounding
1.35 3.34e-03 GO:0023051 regulation of signaling
1.61 4.21e-03 GO:0048666 neuron development
1.32 4.53e-03 GO:0007166 cell surface receptor linked signaling pathway
1.58 5.07e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.54 6.95e-03 GO:0030182 neuron differentiation
1.28 7.52e-03 GO:0065008 regulation of biological quality
1.60 1.02e-02 GO:0006928 cellular component movement
1.24 1.14e-02 GO:0048518 positive regulation of biological process
1.45 1.68e-02 GO:0006811 ion transport
1.33 2.10e-02 GO:0009653 anatomical structure morphogenesis
1.44 2.12e-02 GO:0050793 regulation of developmental process
1.82 2.25e-02 GO:0006954 inflammatory response
1.42 2.41e-02 GO:0032879 regulation of localization
1.66 2.51e-02 GO:0040008 regulation of growth
1.45 2.64e-02 GO:0048699 generation of neurons
1.43 3.35e-02 GO:0022008 neurogenesis
2.87 4.38e-02 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
1.59 4.78e-02 GO:0030001 metal ion transport

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.50 7.42e-14 GO:0044459 plasma membrane part
1.53 4.65e-08 GO:0005887 integral to plasma membrane
1.53 5.00e-08 GO:0031226 intrinsic to plasma membrane
1.24 4.43e-07 GO:0005886 plasma membrane
1.24 4.45e-07 GO:0071944 cell periphery
1.88 3.26e-03 GO:0016323 basolateral plasma membrane
1.49 1.51e-02 GO:0030054 cell junction
1.40 3.04e-02 GO:0005624 membrane fraction
1.68 3.27e-02 GO:0044456 synapse part
1.38 3.34e-02 GO:0042995 cell projection
2.00 4.22e-02 GO:0009897 external side of plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.18 2.60e-09 GO:0005515 protein binding
1.10 2.41e-08 GO:0005488 binding
4.31 2.08e-06 GO:0003823 antigen binding
1.50 3.11e-05 GO:0005102 receptor binding
1.71 2.45e-04 GO:0030695 GTPase regulator activity
1.66 8.05e-04 GO:0060589 nucleoside-triphosphatase regulator activity
3.19 9.66e-04 GO:0004879 ligand-dependent nuclear receptor activity
1.44 1.25e-03 GO:0001071 nucleic acid binding transcription factor activity
1.44 1.25e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
3.21 1.61e-03 GO:0003707 steroid hormone receptor activity
2.28 3.31e-03 GO:0015276 ligand-gated ion channel activity
2.28 3.31e-03 GO:0022834 ligand-gated channel activity
1.66 3.79e-03 GO:0015267 channel activity
1.66 4.17e-03 GO:0022803 passive transmembrane transporter activity
1.42 4.70e-03 GO:0030234 enzyme regulator activity
1.80 9.05e-03 GO:0005261 cation channel activity
1.53 1.29e-02 GO:0008324 cation transmembrane transporter activity
1.45 1.32e-02 GO:0015075 ion transmembrane transporter activity
1.72 1.53e-02 GO:0022836 gated channel activity
1.45 2.02e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.01 2.05e-02 GO:0005085 guanyl-nucleotide exchange factor activity
1.46 2.33e-02 GO:0043565 sequence-specific DNA binding
1.48 2.67e-02 GO:0004672 protein kinase activity
1.60 2.74e-02 GO:0022838 substrate-specific channel activity
1.69 4.35e-02 GO:0005083 small GTPase regulator activity