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• Activity deltas table
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Motif ID: TCF4_dimer.p2

Z-value: 2.809

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chrX_-_13956530	53.798		GPM6B	glycoprotein M6B
chr12_-_49392909	51.755	NM_015086	DDN	dendrin
chr3_-_195310985	51.495	NM_001647	APOD	apolipoprotein D
chr18_-_74691951	51.429		MBP	myelin basic protein
chrX_-_13956644	49.023	NM_001001994	GPM6B	glycoprotein M6B
chr1_+_1981902	43.194	NM_002744	PRKCZ	protein kinase C, zeta
chrX_-_13956445	40.238
chr17_+_38119225	39.974	NM_178171	GSDMA	gasdermin A
chr11_+_73358593	39.937	NM_001130034 NM_001130035	PLEKHB1	pleckstrin homology domain containing, family B (evectins) member 1
chr3_-_195310770	39.812		APOD	apolipoprotein D
chr22_+_41777932	38.633	NM_003216	TEF	thyrotrophic embryonic factor
chr5_+_173472692	36.860	NM_015980	HMP19	HMP19 protein
chr1_+_150255228	35.380	NM_144697	C1orf51	chromosome 1 open reading frame 51
chr7_-_124405029	33.203		GPR37	G protein-coupled receptor 37 (endothelin receptor type B-like)
chr14_-_23821423	30.012	NM_020372	SLC22A17	solute carrier family 22, member 17
chr19_+_36359346	29.897	NM_001024807 NM_005166	APLP1	amyloid beta (A4) precursor-like protein 1
chr22_-_19511777	29.371		CLDN5	claudin 5
chr7_-_22396511	28.705	NM_012294	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5
chr6_-_136871542	28.473		MAP7	microtubule-associated protein 7
chr10_+_124220990	28.338	NM_002775	HTRA1	HtrA serine peptidase 1
chr19_+_18794487	28.255		CRTC1	CREB regulated transcription coactivator 1
chr15_-_76030958	28.069		DNM1P35	DNM1 pseudogene 35
chrX_+_110339374	28.062	NM_002578	PAK3	p21 protein (Cdc42/Rac)-activated kinase 3
chr14_+_100150596	27.926	NM_006668	CYP46A1	cytochrome P450, family 46, subfamily A, polypeptide 1
chr11_-_66725790	27.680	NM_000920 NM_001040716	PC	pyruvate carboxylase
chr5_+_140864626	26.974	NM_018928 NM_032406	PCDHGC4	protocadherin gamma subfamily C, 4
chr3_+_111717585	26.803	NM_001008272 NM_013259	TAGLN3	transgelin 3
chr9_+_17578952	26.529	NM_003026	SH3GL2	SH3-domain GRB2-like 2
chr17_+_40811261	25.344	NM_016437	TUBG2	tubulin, gamma 2
chrX_+_110187468	25.123	NM_001128166 NM_001128167	PAK3	p21 protein (Cdc42/Rac)-activated kinase 3
chr3_+_167453431	24.693	NM_001122752 NM_005025	SERPINI1	serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr2_+_173600519	24.314	NM_007023	RAPGEF4	Rap guanine nucleotide exchange factor (GEF) 4
chr2_+_220283098	24.032	NM_001927	DES	desmin
chr4_+_113970784	23.711	NM_001148 NM_020977	ANK2	ankyrin 2, neuronal
chr15_+_75118950	23.634	NM_001030005	CPLX3	complexin 3
chr3_-_42305438	23.465	NM_001174138	CCK	cholecystokinin
chr19_-_6502224	23.253	NM_006087	TUBB4A	tubulin, beta 4A class IVa
chr5_+_113698304	23.196		KCNN2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr12_-_109458844	22.988	NM_018711	SVOP	SV2 related protein homolog (rat)
chr1_-_144931707	22.841		PDE4DIP	phosphodiesterase 4D interacting protein
chr1_+_60280462	22.760	NM_015888	HOOK1	hook homolog 1 (Drosophila)
chr21_-_42219038	22.610	NM_001389	DSCAM	Down syndrome cell adhesion molecule
chr15_+_44580954	22.378		CASC4	cancer susceptibility candidate 4
chr9_-_93405066	22.323	NM_017594	DIRAS2	DIRAS family, GTP-binding RAS-like 2
chr11_+_118401873	22.176		TMEM25	transmembrane protein 25
chrX_-_13835187	22.095		GPM6B	glycoprotein M6B
chr2_+_79740059	21.723	NM_001164883 NM_004389	CTNNA2	catenin (cadherin-associated protein), alpha 2
chr20_-_590909	21.632	NM_004609	TCF15	transcription factor 15 (basic helix-loop-helix)
chr8_-_110657025	21.421	NM_001099753 NM_001099754 NM_001099755	SYBU	syntabulin (syntaxin-interacting)
chr1_-_233431458	21.189	NM_014801	PCNXL2	pecanex-like 2 (Drosophila)
chr20_+_42839599	21.105		LOC100505783	uncharacterized LOC100505783
chr3_-_195306274	21.079		APOD	apolipoprotein D
chr1_+_2005424	20.786	NM_001242874	PRKCZ	protein kinase C, zeta
chr6_+_31783314	20.774		HSPA1A HSPA1B	heat shock 70kDa protein 1A heat shock 70kDa protein 1B
chr3_+_32148136	20.500		GPD1L	glycerol-3-phosphate dehydrogenase 1-like
chr10_-_135150368	20.333		CALY	calcyon neuron-specific vesicular protein
chr5_+_173472737	20.212		HMP19	HMP19 protein
chr4_-_176923533	20.140		GPM6A	glycoprotein M6A
chr5_+_113698015	19.637	NM_021614	KCNN2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr1_+_65720091	19.632		LOC645195 DNAJC6	uncharacterized LOC645195 DnaJ (Hsp40) homolog, subfamily C, member 6
chr4_+_41258941	19.488		UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr12_-_16759430	19.457		LMO3	LIM domain only 3 (rhombotin-like 2)
chr4_-_176923480	19.362		GPM6A	glycoprotein M6A
chr3_+_35681008	19.215		ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr6_-_62995852	19.070	NM_152688	KHDRBS2	KH domain containing, RNA binding, signal transduction associated 2
chr2_+_173600634	19.043		RAPGEF4	Rap guanine nucleotide exchange factor (GEF) 4
chr5_-_1295022	19.013	NM_001193376 NM_198253	TERT	telomerase reverse transcriptase
chr1_-_17445865	18.921	NM_007365	PADI2	peptidyl arginine deiminase, type II
chr4_-_57976550	18.894	NM_001253835 NM_001553	IGFBP7	insulin-like growth factor binding protein 7
chr19_+_14017038	18.871		CC2D1A	coiled-coil and C2 domain containing 1A
chrX_+_70443055	18.845	NM_000166	GJB1	gap junction protein, beta 1, 32kDa
chr4_-_176923572	18.828	NM_005277 NM_201592	GPM6A	glycoprotein M6A
chr19_+_54058493	18.644	NM_001079907	ZNF331	zinc finger protein 331
chr11_+_62475165	18.624		GNG3	guanine nucleotide binding protein (G protein), gamma 3
chr4_-_57976516	18.602		IGFBP7	insulin-like growth factor binding protein 7
chr19_-_18632857	18.590		ELL	elongation factor RNA polymerase II
chr10_-_135150474	18.560	NM_015722	CALY	calcyon neuron-specific vesicular protein
chr12_-_16759531	18.444	NM_018640	LMO3	LIM domain only 3 (rhombotin-like 2)
chr11_+_113931228	18.434	NM_001018011	ZBTB16	zinc finger and BTB domain containing 16
chr13_+_35516390	18.405	NM_015678	NBEA	neurobeachin
chr2_+_46524448	18.394	NM_001430	EPAS1	endothelial PAS domain protein 1
chr16_+_330605	18.336	NM_001176	ARHGDIG	Rho GDP dissociation inhibitor (GDI) gamma
chr3_+_50712671	17.955	NM_004947	DOCK3	dedicator of cytokinesis 3
chr1_+_203097427	17.874		ADORA1	adenosine A1 receptor
chr17_+_1665233	17.752	NM_002615	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr2_-_224702200	17.719		AP1S3	adaptor-related protein complex 1, sigma 3 subunit
chr19_+_5904842	17.671	NM_001017921	VMAC	vimentin-type intermediate filament associated coiled-coil protein
chr15_-_75660944	17.664		MAN2C1	mannosidase, alpha, class 2C, member 1
chr2_+_17721806	17.631	NM_003385	VSNL1	visinin-like 1
chr17_+_1665281	17.533		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr15_+_74833517	17.360	NM_006465	ARID3B	AT rich interactive domain 3B (BRIGHT-like)
chr6_+_72892371	17.329		RIMS1	regulating synaptic membrane exocytosis 1
chr2_-_68384575	17.282	NM_138458	WDR92	WD repeat domain 92
chr6_+_31783530	17.176		HSPA1A HSPA1B	heat shock 70kDa protein 1A heat shock 70kDa protein 1B
chr17_+_47653474	17.166		NXPH3	neurexophilin 3
chrX_-_13835012	17.154		GPM6B	glycoprotein M6B
chr17_+_42385780	17.091	NM_001144825 NM_001144826 NM_006695	RUNDC3A	RUN domain containing 3A
chr12_-_16758839	16.996	NM_001243612	LMO3	LIM domain only 3 (rhombotin-like 2)
chr4_-_140005344	16.885		ELF2	E74-like factor 2 (ets domain transcription factor)
chr22_-_31741565	16.772		PATZ1	POZ (BTB) and AT hook containing zinc finger 1
chr10_-_21462987	16.671		NEBL	nebulette
chr6_-_46459010	16.649	NM_001251974	RCAN2	regulator of calcineurin 2
chr20_-_3149070	16.633	NM_014731	ProSAPiP1	ProSAPiP1 protein
chr11_+_113930430	16.621	NM_006006	ZBTB16	zinc finger and BTB domain containing 16
chrX_-_50557019	16.601	NM_020717	SHROOM4	shroom family member 4
chr19_-_10341947	16.472	NM_004230	S1PR2	sphingosine-1-phosphate receptor 2
chr6_-_84418705	16.457	NM_001242792	SNAP91	synaptosomal-associated protein, 91kDa homolog (mouse)
chr20_+_44657812	16.396	NM_020708	SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5
chr6_+_111303240	16.386	NM_032194	RPF2	ribosome production factor 2 homolog (S. cerevisiae)
chr17_-_7123368	16.356	NM_001365	DLG4	discs, large homolog 4 (Drosophila)
chr20_+_44657858	16.334		SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5
chrX_-_13835213	16.328		GPM6B	glycoprotein M6B
chr2_+_17721983	16.192		VSNL1	visinin-like 1
chr6_-_136871956	16.135	NM_001198616 NM_001198617 NM_003980	MAP7	microtubule-associated protein 7
chr15_-_83316621	16.026	NM_030594	CPEB1	cytoplasmic polyadenylation element binding protein 1
chr8_+_136470108	15.980		KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3
chr3_+_111718006	15.933	NM_001008273	TAGLN3	transgelin 3
chr11_+_6280903	15.779	NM_176875	CCKBR	cholecystokinin B receptor
chr22_+_22712091	15.777		IGLV1-44 IGL@	immunoglobulin lambda variable 1-44 immunoglobulin lambda locus
chr2_+_233562042	15.560		GIGYF2	GRB10 interacting GYF protein 2
chr9_-_91793375	15.557		SHC3	SHC (Src homology 2 domain containing) transforming protein 3
chr17_+_1665306	15.539		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr8_-_22089517	15.523		PHYHIP	phytanoyl-CoA 2-hydroxylase interacting protein
chr10_-_11653529	15.486	NM_014688	USP6NL	USP6 N-terminal like
chr9_+_6757636	15.455	NM_001146694 NM_001146695 NM_015061	KDM4C	lysine (K)-specific demethylase 4C
chr9_-_35689902	15.405	NM_003289 NM_213674	TPM2	tropomyosin 2 (beta)
chr1_+_206224282	15.369	NM_000707	AVPR1B	arginine vasopressin receptor 1B
chr2_+_173600595	15.317		RAPGEF4	Rap guanine nucleotide exchange factor (GEF) 4
chr16_-_4322695	15.316		TFAP4	transcription factor AP-4 (activating enhancer binding protein 4)
chr7_-_767286	15.220	NM_001164758 NM_001164759	PRKAR1B	protein kinase, cAMP-dependent, regulatory, type I, beta
chr1_-_182361311	15.191	NM_001033044 NM_002065	GLUL	glutamate-ammonia ligase
chr2_-_89292396	15.181		IGKC	immunoglobulin kappa constant
chr19_-_36523540	15.155	NM_001199570	CLIP3	CAP-GLY domain containing linker protein 3
chr19_-_12886263	15.145		HOOK2	hook homolog 2 (Drosophila)
chr1_-_52831817	15.135	NM_032449	CC2D1B	coiled-coil and C2 domain containing 1B
chr17_+_47653176	15.130	NM_007225	NXPH3	neurexophilin 3
chr4_-_57522469	15.121	NM_001145459 NM_139211	HOPX	HOP homeobox
chr17_+_53342356	15.117		HLF	hepatic leukemia factor
chr10_+_99258615	15.081	NM_024954	UBTD1	ubiquitin domain containing 1
chr12_+_79258517	15.078		SYT1	synaptotagmin I
chr12_+_122459791	15.067	NM_001024808 NM_020993	BCL7A	B-cell CLL/lymphoma 7A
chr6_-_39197225	15.054	NM_003740	KCNK5	potassium channel, subfamily K, member 5
chr19_+_35773409	15.022	NM_021175	HAMP	hepcidin antimicrobial peptide
chr14_-_64970319	15.021	NM_006977	ZBTB25	zinc finger and BTB domain containing 25
chrX_+_103031797	15.017		PLP1	proteolipid protein 1
chr19_+_54042041	14.923	NM_001253800	ZNF331	zinc finger protein 331
chr5_-_178772328	14.918		ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr4_-_57976355	14.918		IGFBP7	insulin-like growth factor binding protein 7
chr22_-_38379868	14.908		SOX10	SRY (sex determining region Y)-box 10
chr7_-_79082870	14.893	NM_012301	MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr8_-_144241456	14.843	NM_002347	LY6H	lymphocyte antigen 6 complex, locus H
chr10_-_62149487	14.835	NM_020987	ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chr18_-_5630629	14.800		EPB41L3	erythrocyte membrane protein band 4.1-like 3
chr7_-_8301767	14.799	NM_001136020	ICA1	islet cell autoantigen 1, 69kDa
chr13_+_48877950	14.751		RB1	retinoblastoma 1
chr10_-_21463019	14.747	NM_001173484 NM_213569	NEBL	nebulette
chr5_+_156693051	14.736	NM_001037333 NM_001037332	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr10_-_102988688	14.612	NM_006562	LBX1	ladybird homeobox 1
chr11_-_125366048	14.586	NM_005103 NM_022549	FEZ1	fasciculation and elongation protein zeta 1 (zygin I)
chr17_-_29624249	14.583	NM_002544	OMG	oligodendrocyte myelin glycoprotein
chr19_-_49658645	14.577	NM_002152	HRC	histidine rich calcium binding protein
chr5_+_55033844	14.569	NM_001142549 NM_001166533 NM_024415	DDX4	DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr13_-_28674646	14.550	NM_004119	FLT3	fms-related tyrosine kinase 3
chr11_-_695010	14.532		DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)
chr19_-_18632886	14.517	NM_006532	ELL	elongation factor RNA polymerase II
chr8_+_38034066	14.495	NM_001204878 NM_004874	BAG4	BCL2-associated athanogene 4
chr17_-_7197811	14.478		YBX2	Y box binding protein 2
chr21_-_42218587	14.458		DSCAM	Down syndrome cell adhesion molecule
chr19_-_46974663	14.451		PNMAL1	PNMA-like 1
chr14_+_69865380	14.439	NM_001252148 NM_001252150 NM_018375	SLC39A9	solute carrier family 39 (zinc transporter), member 9
chr20_+_1246959	14.409	NM_014723	SNPH	syntaphilin
chr2_+_46524901	14.354		EPAS1	endothelial PAS domain protein 1
chr16_-_57318574	14.335	NM_015993	PLLP	plasmolipin
chr11_+_125774271	14.204	NM_013264	DDX25	DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr8_-_127570465	14.201		FAM84B	family with sequence similarity 84, member B
chr2_+_203499819	14.152	NM_173511	FAM117B	family with sequence similarity 117, member B
chr19_+_35782988	14.127	NM_001199216 NM_002361 NM_080600	MAG	myelin associated glycoprotein
chr10_+_105037441	14.055		INA	internexin neuronal intermediate filament protein, alpha
chr3_+_52444673	13.990		PHF7	PHD finger protein 7
chr7_+_94023872	13.913	NM_000089	COL1A2	collagen, type I, alpha 2
chr22_+_22735207	13.899		IGLJ3	immunoglobulin lambda joining 3
chr11_-_33890931	13.887		LMO2	LIM domain only 2 (rhombotin-like 1)
chr11_+_12132063	13.878	NM_014632	MICAL2	microtubule associated monoxygenase, calponin and LIM domain containing 2
chr17_-_79139871	13.877	NM_001080395	AATK	apoptosis-associated tyrosine kinase
chr17_-_7197896	13.853		YBX2	Y box binding protein 2
chr19_+_19322763	13.840	NM_004386	NCAN	neurocan
chr7_-_3083346	13.781	NM_032415	CARD11	caspase recruitment domain family, member 11
chr6_+_89855745	13.763	NM_001010853	PM20D2	peptidase M20 domain containing 2
chr7_-_143059144	13.753	NM_014690	FAM131B	family with sequence similarity 131, member B
chr6_-_46293404	13.746		RCAN2	regulator of calcineurin 2
chr1_-_182360889	13.692		GLUL	glutamate-ammonia ligase
chr6_+_87865261	13.664	NM_015021	ZNF292	zinc finger protein 292
chr11_+_62475113	13.575	NM_012202	GNG3	guanine nucleotide binding protein (G protein), gamma 3
chr12_+_79258588	13.564		SYT1	synaptotagmin I
chr16_+_69796237	13.531	NM_007014 NM_199423	WWP2	WW domain containing E3 ubiquitin protein ligase 2
chr19_+_41107220	13.523	NM_001042545	LTBP4	latent transforming growth factor beta binding protein 4
chr19_+_40973049	13.512	NM_020971	SPTBN4	spectrin, beta, non-erythrocytic 4
chr11_-_45307617	13.508	NM_001247987 NM_020826	SYT13	synaptotagmin XIII
chr14_+_69865095	13.478	NM_001252151 NM_001252152	SLC39A9	solute carrier family 39 (zinc transporter), member 9
chr17_+_5972425	13.431		WSCD1	WSC domain containing 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.42	1.82e-38	GO:0048856	anatomical structure development
1.44	2.71e-36	GO:0048731	system development
1.35	3.89e-33	GO:0032502	developmental process
1.37	1.08e-32	GO:0007275	multicellular organismal development
1.27	1.89e-31	GO:0032501	multicellular organismal process
1.20	3.97e-31	GO:0065007	biological regulation
1.33	4.40e-29	GO:0023052	signaling
1.54	3.11e-25	GO:0007399	nervous system development
1.11	1.29e-24	GO:0009987	cellular process
1.18	8.40e-24	GO:0050789	regulation of biological process
1.44	2.94e-22	GO:0048513	organ development
1.18	7.59e-22	GO:0050794	regulation of cellular process
1.71	7.11e-21	GO:0007267	cell-cell signaling
1.41	1.39e-20	GO:0030154	cell differentiation
1.39	5.59e-20	GO:0048869	cellular developmental process
1.52	1.19e-19	GO:0051239	regulation of multicellular organismal process
1.29	8.03e-19	GO:0007165	signal transduction
1.47	8.19e-19	GO:0009653	anatomical structure morphogenesis
1.37	1.51e-17	GO:0065008	regulation of biological quality
1.56	1.82e-17	GO:0007154	cell communication
1.24	3.25e-17	GO:0051716	cellular response to stimulus
1.80	2.40e-16	GO:0019226	transmission of nerve impulse
1.80	2.40e-16	GO:0035637	multicellular organismal signaling
1.57	2.66e-16	GO:0048468	cell development
1.34	2.71e-16	GO:0042221	response to chemical stimulus
1.17	8.81e-16	GO:0050896	response to stimulus
1.38	2.81e-15	GO:0007166	cell surface receptor linked signaling pathway
1.80	1.67e-14	GO:0007268	synaptic transmission
1.52	2.05e-13	GO:0022008	neurogenesis
1.54	3.35e-13	GO:0048699	generation of neurons
1.65	3.39e-13	GO:0009887	organ morphogenesis
1.60	3.53e-13	GO:0030182	neuron differentiation
1.51	1.40e-12	GO:0050793	regulation of developmental process
1.56	3.97e-12	GO:2000026	regulation of multicellular organismal development
1.63	1.24e-11	GO:0048666	neuron development
2.14	1.41e-11	GO:0003012	muscle system process
2.17	3.54e-11	GO:0006936	muscle contraction
1.80	1.41e-10	GO:0044057	regulation of system process
1.34	2.64e-10	GO:0023051	regulation of signaling
1.25	4.20e-10	GO:0048518	positive regulation of biological process
1.47	8.72e-10	GO:0040011	locomotion
1.21	1.66e-09	GO:0051179	localization
1.43	2.56e-09	GO:0032879	regulation of localization
1.77	5.18e-09	GO:0007610	behavior
1.60	7.84e-09	GO:0007417	central nervous system development
1.28	3.95e-08	GO:0048583	regulation of response to stimulus
1.32	5.10e-08	GO:0065009	regulation of molecular function
1.24	1.64e-07	GO:0048522	positive regulation of cellular process
1.56	1.81e-07	GO:0000904	cell morphogenesis involved in differentiation
1.50	2.13e-07	GO:0048878	chemical homeostasis
1.41	2.13e-07	GO:0006811	ion transport
1.60	2.16e-07	GO:0048667	cell morphogenesis involved in neuron differentiation
1.59	2.35e-07	GO:0051094	positive regulation of developmental process
1.52	3.66e-07	GO:0007186	G-protein coupled receptor protein signaling pathway
1.48	5.95e-07	GO:0032989	cellular component morphogenesis
1.59	6.88e-07	GO:0007409	axonogenesis
1.46	7.49e-07	GO:0045595	regulation of cell differentiation
1.36	7.97e-07	GO:0010646	regulation of cell communication
1.34	8.53e-07	GO:0050790	regulation of catalytic activity
1.70	9.15e-07	GO:0019932	second-messenger-mediated signaling
1.57	9.88e-07	GO:0048812	neuron projection morphogenesis
1.17	1.07e-06	GO:0019222	regulation of metabolic process
1.23	1.12e-06	GO:0048519	negative regulation of biological process
1.47	1.34e-06	GO:0030030	cell projection organization
1.24	1.60e-06	GO:0048523	negative regulation of cellular process
1.55	1.66e-06	GO:0050801	ion homeostasis
1.51	2.94e-06	GO:0006935	chemotaxis
1.51	2.94e-06	GO:0042330	taxis
1.39	3.48e-06	GO:0009888	tissue development
1.66	4.17e-06	GO:0022603	regulation of anatomical structure morphogenesis
1.65	4.84e-06	GO:0001501	skeletal system development
1.36	5.35e-06	GO:0009605	response to external stimulus
1.55	5.76e-06	GO:0006873	cellular ion homeostasis
1.53	5.79e-06	GO:0072358	cardiovascular system development
1.53	5.79e-06	GO:0072359	circulatory system development
1.51	6.42e-06	GO:0031175	neuron projection development
2.17	6.96e-06	GO:0045761	regulation of adenylate cyclase activity
1.54	6.98e-06	GO:0055082	cellular chemical homeostasis
1.36	7.09e-06	GO:0042127	regulation of cell proliferation
1.29	7.45e-06	GO:0009966	regulation of signal transduction
1.98	8.59e-06	GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger
1.68	8.73e-06	GO:0007423	sensory organ development
1.62	8.86e-06	GO:0007411	axon guidance
1.40	1.02e-05	GO:0007155	cell adhesion
1.40	1.02e-05	GO:0022610	biological adhesion
1.26	1.15e-05	GO:0003008	system process
1.64	1.46e-05	GO:0006140	regulation of nucleotide metabolic process
1.92	1.59e-05	GO:0019935	cyclic-nucleotide-mediated signaling
2.13	1.78e-05	GO:0031279	regulation of cyclase activity
2.01	1.88e-05	GO:0030802	regulation of cyclic nucleotide biosynthetic process
2.01	1.88e-05	GO:0030808	regulation of nucleotide biosynthetic process
1.99	2.04e-05	GO:0030799	regulation of cyclic nucleotide metabolic process
1.45	2.36e-05	GO:0000902	cell morphogenesis
1.78	2.97e-05	GO:0003013	circulatory system process
1.78	2.97e-05	GO:0008015	blood circulation
1.29	3.09e-05	GO:0035556	intracellular signal transduction
1.96	3.23e-05	GO:0042391	regulation of membrane potential
1.46	3.45e-05	GO:0051336	regulation of hydrolase activity
1.18	3.55e-05	GO:0006810	transport
2.04	3.99e-05	GO:0019933	cAMP-mediated signaling
1.18	4.05e-05	GO:0051234	establishment of localization
1.34	4.28e-05	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.42	4.29e-05	GO:0007167	enzyme linked receptor protein signaling pathway
2.09	4.37e-05	GO:0051339	regulation of lyase activity
2.03	4.41e-05	GO:0030817	regulation of cAMP biosynthetic process
2.09	5.99e-05	GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger
2.01	6.61e-05	GO:0030814	regulation of cAMP metabolic process
2.01	6.61e-05	GO:0050804	regulation of synaptic transmission
1.37	6.66e-05	GO:0055085	transmembrane transport
1.39	6.71e-05	GO:0051049	regulation of transport
1.47	9.16e-05	GO:0048858	cell projection morphogenesis
1.58	9.49e-05	GO:0045597	positive regulation of cell differentiation
1.47	1.02e-04	GO:0032990	cell part morphogenesis
1.40	1.47e-04	GO:0010628	positive regulation of gene expression
2.76	1.82e-04	GO:0006941	striated muscle contraction
1.15	1.84e-04	GO:0080090	regulation of primary metabolic process
1.90	1.91e-04	GO:0060191	regulation of lipase activity
2.04	1.93e-04	GO:0007202	activation of phospholipase C activity
1.48	2.41e-04	GO:0048870	cell motility
1.48	2.41e-04	GO:0051674	localization of cell
1.91	2.49e-04	GO:0051969	regulation of transmission of nerve impulse
1.97	2.71e-04	GO:0060193	positive regulation of lipase activity
2.02	2.92e-04	GO:0010863	positive regulation of phospholipase C activity
2.15	3.00e-04	GO:0008016	regulation of heart contraction
1.61	3.16e-04	GO:0061061	muscle structure development
1.53	3.60e-04	GO:0007420	brain development
1.33	3.85e-04	GO:0042592	homeostatic process
1.46	4.00e-04	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.33	4.47e-04	GO:0009611	response to wounding
1.18	4.73e-04	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.98	4.74e-04	GO:0010518	positive regulation of phospholipase activity
1.38	4.87e-04	GO:0009719	response to endogenous stimulus
1.48	6.31e-04	GO:0016477	cell migration
1.71	7.10e-04	GO:0007517	muscle organ development
1.54	1.02e-03	GO:0051093	negative regulation of developmental process
1.82	1.04e-03	GO:0031644	regulation of neurological system process
1.93	1.07e-03	GO:0010517	regulation of phospholipase activity
1.26	1.08e-03	GO:0010033	response to organic substance
1.43	1.26e-03	GO:0001775	cell activation
1.14	1.37e-03	GO:0031323	regulation of cellular metabolic process
1.30	1.52e-03	GO:0070887	cellular response to chemical stimulus
1.41	1.55e-03	GO:0019725	cellular homeostasis
1.40	1.83e-03	GO:0006928	cellular component movement
1.34	1.90e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.45	2.01e-03	GO:0007422	peripheral nervous system development
2.07	2.18e-03	GO:0048706	embryonic skeletal system development
2.58	2.31e-03	GO:0070252	actin-mediated cell contraction
1.76	2.58e-03	GO:0048562	embryonic organ morphogenesis
1.32	2.65e-03	GO:0044093	positive regulation of molecular function
1.41	2.79e-03	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.26	3.01e-03	GO:0002376	immune system process
2.26	3.45e-03	GO:0007194	negative regulation of adenylate cyclase activity
2.26	3.45e-03	GO:0031280	negative regulation of cyclase activity
2.26	3.45e-03	GO:0051350	negative regulation of lyase activity
1.16	3.78e-03	GO:0051171	regulation of nitrogen compound metabolic process
1.37	4.18e-03	GO:0009725	response to hormone stimulus
1.34	4.30e-03	GO:0043085	positive regulation of catalytic activity
1.32	4.34e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.80	4.71e-03	GO:0001503	ossification
1.36	5.46e-03	GO:0045893	positive regulation of transcription, DNA-dependent
1.87	5.76e-03	GO:0007611	learning or memory
2.54	6.03e-03	GO:0030049	muscle filament sliding
2.54	6.03e-03	GO:0033275	actin-myosin filament sliding
1.80	6.37e-03	GO:0048705	skeletal system morphogenesis
1.44	6.86e-03	GO:0040008	regulation of growth
1.43	7.55e-03	GO:0008285	negative regulation of cell proliferation
1.88	7.60e-03	GO:0006836	neurotransmitter transport
1.37	8.10e-03	GO:0006812	cation transport
1.14	8.38e-03	GO:0016043	cellular component organization
1.82	8.48e-03	GO:0050890	cognition
1.53	8.66e-03	GO:0051345	positive regulation of hydrolase activity
1.50	9.17e-03	GO:0051046	regulation of secretion
1.58	9.17e-03	GO:0007507	heart development
1.58	9.61e-03	GO:0030168	platelet activation
1.16	1.00e-02	GO:0031326	regulation of cellular biosynthetic process
1.47	1.10e-02	GO:0051240	positive regulation of multicellular organismal process
2.38	1.22e-02	GO:0007193	inhibition of adenylate cyclase activity by G-protein signaling pathway
2.24	1.47e-02	GO:0030048	actin filament-based movement
1.57	1.55e-02	GO:0048568	embryonic organ development
1.15	1.61e-02	GO:0009889	regulation of biosynthetic process
1.41	1.64e-02	GO:0060341	regulation of cellular localization
1.63	1.69e-02	GO:0048732	gland development
1.50	1.86e-02	GO:0051270	regulation of cellular component movement
1.47	1.98e-02	GO:0032535	regulation of cellular component size
1.41	2.08e-02	GO:0032583	regulation of gene-specific transcription
2.15	2.11e-02	GO:0034339	regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
1.53	2.55e-02	GO:0008361	regulation of cell size
1.32	2.68e-02	GO:0051254	positive regulation of RNA metabolic process
2.08	2.76e-02	GO:0001508	regulation of action potential
1.50	2.85e-02	GO:0040012	regulation of locomotion
1.43	2.87e-02	GO:0090066	regulation of anatomical structure size
1.40	3.18e-02	GO:0071702	organic substance transport
1.60	3.21e-02	GO:0010817	regulation of hormone levels
1.81	3.83e-02	GO:0008217	regulation of blood pressure
1.16	3.90e-02	GO:0006950	response to stress
3.01	4.21e-02	GO:0042551	neuron maturation
1.37	4.23e-02	GO:0048585	negative regulation of response to stimulus
1.22	4.37e-02	GO:0009893	positive regulation of metabolic process
1.46	4.50e-02	GO:0060284	regulation of cell development
1.37	4.51e-02	GO:0030001	metal ion transport
1.32	4.59e-02	GO:0001932	regulation of protein phosphorylation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.44	4.63e-29	GO:0044459	plasma membrane part
1.53	3.46e-22	GO:0031226	intrinsic to plasma membrane
1.53	8.65e-22	GO:0005887	integral to plasma membrane
1.20	5.91e-13	GO:0005886	plasma membrane
1.20	2.72e-12	GO:0071944	cell periphery
1.48	1.03e-10	GO:0005615	extracellular space
1.46	2.29e-10	GO:0005626	insoluble fraction
1.41	2.39e-10	GO:0044421	extracellular region part
1.45	1.02e-09	GO:0005624	membrane fraction
1.34	1.20e-07	GO:0000267	cell fraction
1.48	1.22e-07	GO:0030054	cell junction
1.58	1.78e-07	GO:0045202	synapse
1.56	9.54e-07	GO:0043005	neuron projection
1.22	4.36e-06	GO:0005576	extracellular region
1.80	7.22e-06	GO:0044297	cell body
1.80	9.69e-06	GO:0043025	neuronal cell body
1.34	1.11e-05	GO:0042995	cell projection
1.08	1.60e-05	GO:0005737	cytoplasm
1.64	6.27e-05	GO:0016323	basolateral plasma membrane
1.89	6.52e-05	GO:0043292	contractile fiber
1.48	1.85e-04	GO:0031012	extracellular matrix
1.32	2.44e-04	GO:0031982	vesicle
1.87	3.17e-04	GO:0030016	myofibril
1.33	3.44e-04	GO:0031988	membrane-bounded vesicle
1.63	3.64e-04	GO:0034702	ion channel complex
1.65	5.93e-04	GO:0030425	dendrite
1.32	6.29e-04	GO:0031410	cytoplasmic vesicle
1.67	6.72e-04	GO:0030424	axon
1.32	9.29e-04	GO:0016023	cytoplasmic membrane-bounded vesicle
1.07	1.75e-03	GO:0016020	membrane
1.47	1.99e-03	GO:0044433	cytoplasmic vesicle part
1.48	3.84e-03	GO:0044456	synapse part
1.77	5.21e-03	GO:0044449	contractile fiber part
2.38	9.76e-03	GO:0005581	collagen
1.54	1.47e-02	GO:0005911	cell-cell junction
1.45	1.87e-02	GO:0012506	vesicle membrane
1.75	3.14e-02	GO:0030017	sarcomere
2.37	4.35e-02	GO:0043204	perikaryon
1.35	4.40e-02	GO:0044463	cell projection part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.14	1.21e-13	GO:0005515	protein binding
1.07	1.21e-11	GO:0005488	binding
1.42	2.67e-10	GO:0005102	receptor binding
1.46	1.05e-07	GO:0043565	sequence-specific DNA binding
1.37	1.08e-07	GO:0001071	nucleic acid binding transcription factor activity
1.37	1.08e-07	GO:0003700	sequence-specific DNA binding transcription factor activity
1.38	1.41e-07	GO:0022857	transmembrane transporter activity
1.32	8.03e-07	GO:0005215	transporter activity
1.35	8.96e-07	GO:0022892	substrate-specific transporter activity
1.37	1.18e-06	GO:0022891	substrate-specific transmembrane transporter activity
1.40	3.24e-06	GO:0015075	ion transmembrane transporter activity
1.50	2.75e-05	GO:0022803	passive transmembrane transporter activity
2.33	2.87e-05	GO:0005496	steroid binding
1.50	4.21e-05	GO:0015267	channel activity
2.49	4.82e-05	GO:0003707	steroid hormone receptor activity
1.31	6.64e-05	GO:0030528	transcription regulator activity
2.42	6.88e-05	GO:0004879	ligand-dependent nuclear receptor activity
1.40	2.72e-04	GO:0008324	cation transmembrane transporter activity
1.47	3.17e-04	GO:0022838	substrate-specific channel activity
1.53	3.30e-04	GO:0022836	gated channel activity
1.34	3.55e-04	GO:0042802	identical protein binding
1.46	6.36e-04	GO:0005216	ion channel activity
1.42	6.63e-04	GO:0060589	nucleoside-triphosphatase regulator activity
1.42	8.59e-04	GO:0030695	GTPase regulator activity
1.43	9.01e-04	GO:0008289	lipid binding
1.35	1.02e-03	GO:0046983	protein dimerization activity
1.42	1.79e-03	GO:0042803	protein homodimerization activity
1.27	2.49e-03	GO:0030234	enzyme regulator activity
3.32	3.70e-03	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity
1.67	4.45e-03	GO:0005085	guanyl-nucleotide exchange factor activity
1.50	6.65e-03	GO:0005261	cation channel activity
1.48	8.02e-03	GO:0005083	small GTPase regulator activity
1.43	9.50e-03	GO:0022804	active transmembrane transporter activity
1.67	1.10e-02	GO:0008509	anion transmembrane transporter activity
2.73	1.91e-02	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
1.33	2.77e-02	GO:0008092	cytoskeletal protein binding
1.65	3.38e-02	GO:0005516	calmodulin binding
1.42	3.83e-02	GO:0016563	transcription activator activity
2.62	4.09e-02	GO:0004112	cyclic-nucleotide phosphodiesterase activity