Motif ID: TFEB.p2

Z-value: 2.361


Transcription factors associated with TFEB.p2:

Gene SymbolEntrez IDGene Name
TFEB 7942 transcription factor EB

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFEBchr6_-_41702734,
chr6_-_41703938
0.211.9e-03Click!


Activity profile for motif TFEB.p2.

activity profile for motif TFEB.p2


Sorted Z-values histogram for motif TFEB.p2

Sorted Z-values for motif TFEB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFEB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_113951537 91.759 LAMP1
lysosomal-associated membrane protein 1
chr1_-_154193044 83.179 C1orf43
chromosome 1 open reading frame 43
chr13_+_113951461 80.153 NM_005561
LAMP1
lysosomal-associated membrane protein 1
chr19_-_10764449 72.680 LOC147727
uncharacterized LOC147727
chr20_+_44520021 69.536 CTSA
cathepsin A
chr19_+_40854529 64.063 PLD3
phospholipase D family, member 3
chr13_+_113951589 61.333 LAMP1
lysosomal-associated membrane protein 1
chr16_-_1525020 61.067 CLCN7
chloride channel 7
chr20_+_44519924 58.729 CTSA
cathepsin A
chr20_+_44519965 55.447 CTSA
cathepsin A
chr1_+_11866240 49.304 CLCN6
chloride channel 6
chr16_-_67514989 48.954 NM_004691
ATP6V0D1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr15_-_72668184 47.654 HEXA
hexosaminidase A (alpha polypeptide)
chr16_-_1525006 45.935 CLCN7
chloride channel 7
chr18_+_9708322 39.285 RAB31
RAB31, member RAS oncogene family
chr19_+_7587436 37.730 NM_020533
MCOLN1
mucolipin 1
chr4_+_128651518 34.403 NM_031291
SLC25A31
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr19_+_5681139 33.956 HSD11B1L
hydroxysteroid (11-beta) dehydrogenase 1-like
chr1_+_154193294 33.611 NM_014847
UBAP2L
ubiquitin associated protein 2-like
chr1_-_11865963 33.300 MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr18_+_9708299 33.118 RAB31
RAB31, member RAS oncogene family
chr16_+_69796237 31.844 NM_007014
NM_199423
WWP2

WW domain containing E3 ubiquitin protein ligase 2

chrX_+_102470003 31.728 NM_001080425
NM_001127688
BEX4

brain expressed, X-linked 4

chr11_-_1785104 31.464 CTSD
cathepsin D
chr5_-_172198160 30.984 NM_004417
DUSP1
dual specificity phosphatase 1
chr3_+_112280911 30.885 SLC35A5
solute carrier family 35, member A5
chr3_+_158519911 30.791 MFSD1
major facilitator superfamily domain containing 1
chr7_+_23286390 30.490 GPNMB
glycoprotein (transmembrane) nmb
chr7_+_23286384 30.151 GPNMB
glycoprotein (transmembrane) nmb
chr16_-_1525040 30.124 NM_001114331
NM_001287
CLCN7

chloride channel 7

chr20_+_44520203 30.090 CTSA
cathepsin A
chr7_+_23286386 29.886 GPNMB
glycoprotein (transmembrane) nmb
chrX_+_102631408 29.622 NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr11_-_1785087 29.481 CTSD
cathepsin D
chr3_-_4508939 29.211 SUMF1
sulfatase modifying factor 1
chr3_+_112280871 29.140 NM_017945
SLC35A5
solute carrier family 35, member A5
chr17_+_18218569 28.692 NM_144775
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr6_+_31982538 28.599 NM_001242823
NM_001252204
NM_007293
NM_001002029
LOC100293534
C4A

C4B
complement C4-B-like
complement component 4A (Rodgers blood group)

complement component 4B (Chido blood group)
chr18_+_9708269 28.399 RAB31
RAB31, member RAS oncogene family
chr6_+_31949800 27.947 NM_001242823
NM_001252204
NM_007293
NM_001002029
LOC100293534
C4A

C4B
complement C4-B-like
complement component 4A (Rodgers blood group)

complement component 4B (Chido blood group)
chr12_-_56122748 27.687 CD63
CD63 molecule
chr12_-_56122840 27.563 NM_001040034
NM_001780
CD63

CD63 molecule

chr16_+_8806825 27.469 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr17_+_6915952 27.437 RNASEK
ribonuclease, RNase K
chr12_-_56122792 27.435 CD63
CD63 molecule
chr12_-_65153189 26.901 NM_002076
GNS
glucosamine (N-acetyl)-6-sulfatase
chr15_-_72668301 26.773 NM_000520
HEXA
hexosaminidase A (alpha polypeptide)
chr15_-_73925555 26.270 NPTN
neuroplastin
chr10_-_73610958 26.095 PSAP
prosaposin
chr12_-_56122800 26.044 CD63
CD63 molecule
chr17_+_79885567 26.004 LOC92659
uncharacterized LOC92659
chr11_+_118938528 25.542 VPS11
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr3_+_128445024 25.152 RAB7A
RAB7A, member RAS oncogene family
chr3_-_20227618 24.957 NM_001012409
NM_001012410
NM_001012411
NM_001012412
NM_001012413
NM_138484
NM_001199251
NM_001199252
NM_001199253
NM_001199254
NM_001199255
NM_001199256
NM_001199257
SGOL1












shugoshin-like 1 (S. pombe)












chr17_+_78075390 24.892 GAA
glucosidase, alpha; acid
chr15_-_50978983 24.864 NM_017672
TRPM7
transient receptor potential cation channel, subfamily M, member 7
chr19_-_48018317 24.590 NM_003827
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chrX_-_100914816 24.448 NM_014782
NM_177949
ARMCX2

armadillo repeat containing, X-linked 2

chr9_+_74526527 24.357 C9orf85
chromosome 9 open reading frame 85
chr9_+_115913266 24.310 SLC31A2
solute carrier family 31 (copper transporters), member 2
chr11_+_118938515 24.102 VPS11
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr14_-_81687265 23.766 NM_015859
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr11_+_118938473 23.753 NM_021729
VPS11
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr9_+_115913227 23.704 NM_001860
SLC31A2
solute carrier family 31 (copper transporters), member 2
chr7_+_23286420 23.704 GPNMB
glycoprotein (transmembrane) nmb
chr3_+_51428720 23.420 RBM15B
RNA binding motif protein 15B
chr9_-_123476578 23.369 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr16_+_85061303 23.311 NM_014732
KIAA0513
KIAA0513
chr3_-_112280759 22.985 ATG3
ATG3 autophagy related 3 homolog (S. cerevisiae)
chr3_+_128444978 22.861 NM_004637
RAB7A
RAB7A, member RAS oncogene family
chr2_+_220042901 22.774 NM_024293
FAM134A
family with sequence similarity 134, member A
chr17_-_46688279 22.687 HOXB7
homeobox B7
chr18_+_9708187 22.561 NM_006868
RAB31
RAB31, member RAS oncogene family
chr1_+_11866206 22.447 NM_001286
NM_021735
NM_021736
NM_021737
CLCN6



chloride channel 6



chr14_+_74551655 22.446 NM_001024674
LIN52
lin-52 homolog (C. elegans)
chr19_+_45409003 22.435 NM_000041
APOE
apolipoprotein E
chr9_-_133454818 22.331 LOC100272217
uncharacterized LOC100272217
chr6_-_84937313 22.328 NM_014895
KIAA1009
KIAA1009
chr1_-_153508597 22.323 NM_014624
S100A6
S100 calcium binding protein A6
chr19_-_5340700 22.312 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chrX_+_101380659 22.172 NM_080390
TCEAL2
transcription elongation factor A (SII)-like 2
chr8_-_11725509 22.169 CTSB
cathepsin B
chr16_-_88923233 22.153 GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chrX_-_13835313 22.099 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr12_+_112451229 22.036


chr3_+_147127151 21.828 NM_003412
ZIC1
Zic family member 1
chr15_-_73925658 21.686 NM_001161363
NM_001161364
NM_012428
NM_017455
NPTN



neuroplastin



chr5_+_172483285 21.650 NM_001168393
NM_001168394
NM_153607
C5orf41


chromosome 5 open reading frame 41


chr19_-_48018277 21.622 NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr12_-_65153182 21.606 GNS
glucosamine (N-acetyl)-6-sulfatase
chr2_+_220042948 21.351 FAM134A
family with sequence similarity 134, member A
chr11_-_1785126 21.320 CTSD
cathepsin D
chr8_-_54755821 21.141 ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr13_-_110438896 21.036 NM_003749
IRS2
insulin receptor substrate 2
chr17_-_7137722 21.019 NM_004422
DVL2
dishevelled, dsh homolog 2 (Drosophila)
chr11_+_118938530 20.997 VPS11
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr5_-_131132642 20.966 FNIP1
folliculin interacting protein 1
chr3_-_49395697 20.927 GPX1
glutathione peroxidase 1
chr8_-_54755836 20.900 NM_015941
NM_213619
ATP6V1H

ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H

chr5_+_150827138 20.642 NM_078483
SLC36A1
solute carrier family 36 (proton/amino acid symporter), member 1
chr7_-_47622127 20.452 TNS3
tensin 3
chr5_-_133706717 20.258 CDKL3
cyclin-dependent kinase-like 3
chr1_+_150255228 20.191 NM_144697
C1orf51
chromosome 1 open reading frame 51
chrX_-_102319080 19.711 BEX1
brain expressed, X-linked 1
chr3_-_49395751 19.707 NM_000581
NM_201397
GPX1

glutathione peroxidase 1

chr7_+_97910978 19.625 NM_001159491
NM_015379
BRI3

brain protein I3

chrX_-_106960268 19.569 NM_004089
TSC22D3
TSC22 domain family, member 3
chr4_+_76439653 19.358 NM_144721
THAP6
THAP domain containing 6
chr8_-_17941598 19.324 ASAH1
N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr7_+_151722774 19.051 NM_022087
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr1_-_11866079 18.991 NM_005957
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr16_+_2570322 18.952 NM_001145815
NM_015944
AMDHD2

amidohydrolase domain containing 2

chr2_+_220042986 18.910 FAM134A
family with sequence similarity 134, member A
chr3_-_170626381 18.770 EIF5A2
eukaryotic translation initiation factor 5A2
chr19_+_5681016 18.685 NM_198704
NM_198705
NM_198533
NM_198707
NM_198706
NM_198708
HSD11B1L





hydroxysteroid (11-beta) dehydrogenase 1-like





chr22_+_35777087 18.518 HMOX1
heme oxygenase (decycling) 1
chr8_-_22089517 18.509 PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr2_-_172967627 18.404 DLX2
distal-less homeobox 2
chr14_-_81687574 18.225 NM_201595
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr1_-_52831817 18.220 NM_032449
CC2D1B
coiled-coil and C2 domain containing 1B
chr17_-_7137580 17.980 DVL2
dishevelled, dsh homolog 2 (Drosophila)
chrX_-_15872882 17.900 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr3_-_170626425 17.891 NM_020390
EIF5A2
eukaryotic translation initiation factor 5A2
chr17_-_18218203 17.814 NM_004618
TOP3A
topoisomerase (DNA) III alpha
chr3_+_158519888 17.773 MFSD1
major facilitator superfamily domain containing 1
chr8_-_17941614 17.746 ASAH1
N-acylsphingosine amidohydrolase (acid ceramidase) 1
chrX_-_102319096 17.692 NM_018476
BEX1
brain expressed, X-linked 1
chr17_-_66951381 17.615 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr11_-_9286832 17.607 NM_001243254
NM_015213
DENND5A

DENN/MADD domain containing 5A

chr1_-_241520467 17.559 NM_002924
RGS7
regulator of G-protein signaling 7
chr19_-_5680910 17.532 NM_205767
C19orf70
chromosome 19 open reading frame 70
chr12_+_51632620 17.454 DAZAP2
DAZ associated protein 2
chr16_+_30960413 17.295 ORAI3
ORAI calcium release-activated calcium modulator 3
chr2_-_176866925 17.213 NM_030650
KIAA1715
KIAA1715
chr3_+_51428698 17.162 NM_013286
RBM15B
RNA binding motif protein 15B
chrX_-_15872938 17.100 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr3_+_128445033 17.092 RAB7A
RAB7A, member RAS oncogene family
chr6_+_7590405 17.076 NM_152551
SNRNP48
small nuclear ribonucleoprotein 48kDa (U11/U12)
chr1_-_68697997 16.906 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr16_+_30960434 16.741 ORAI3
ORAI calcium release-activated calcium modulator 3
chr20_+_43595119 16.718 NM_006282
STK4
serine/threonine kinase 4
chr19_-_11688484 16.695 ACP5
acid phosphatase 5, tartrate resistant
chr12_-_65153148 16.552 GNS
glucosamine (N-acetyl)-6-sulfatase
chr7_-_47621741 16.549 NM_022748
TNS3
tensin 3
chr19_-_11688508 16.495 NM_001611
ACP5
acid phosphatase 5, tartrate resistant
chr8_+_59465727 16.322 NM_001007067
NM_001007068
NM_001007069
NM_001007070
NM_005625
SDCBP




syndecan binding protein (syntenin)




chr12_-_121342050 16.151 NM_139015
SPPL3
signal peptide peptidase-like 3
chr1_-_154928595 16.108 PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr12_+_51632654 16.108 DAZAP2
DAZ associated protein 2
chr2_-_220042731 16.067 CNPPD1
cyclin Pas1/PHO80 domain containing 1
chr16_+_30960377 15.989 NM_152288
ORAI3
ORAI calcium release-activated calcium modulator 3
chr17_+_55055467 15.967 NM_021626
SCPEP1
serine carboxypeptidase 1
chr17_-_73851377 15.884 NM_012478
WBP2
WW domain binding protein 2
chr16_-_5083933 15.873 NM_016256
NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr12_+_51632589 15.817 DAZAP2
DAZ associated protein 2
chr8_-_54755546 15.779 NM_213620
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr6_-_134497069 15.748 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr22_-_21213069 15.584 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr3_-_187463474 15.518 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr16_-_5083913 15.515 NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr22_-_21213099 15.482 NM_058004
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chrX_-_15873094 15.429 NM_003916
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr20_+_43595176 15.382 STK4
serine/threonine kinase 4
chr17_-_38256905 15.140 NM_021724
NR1D1
nuclear receptor subfamily 1, group D, member 1
chrX_-_15872871 14.934 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr1_-_155211049 14.927 NM_001171812
NM_000157
GBA

glucosidase, beta, acid

chr6_-_84418705 14.927 NM_001242792
SNAP91
synaptosomal-associated protein, 91kDa homolog (mouse)
chr8_+_59465798 14.870 SDCBP
syndecan binding protein (syntenin)
chrX_-_106960028 14.853 TSC22D3
TSC22 domain family, member 3
chr9_-_131709783 14.762 NM_014908
DOLK
dolichol kinase
chrX_-_15872921 14.739 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr15_+_74422920 14.703 ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr1_-_241520384 14.701 RGS7
regulator of G-protein signaling 7
chr10_-_14050453 14.700 FRMD4A
FERM domain containing 4A
chr12_-_112450914 14.683 NM_001193453
NM_001193531
NM_138341
LOC728543
TMEM116


uncharacterized LOC728543
transmembrane protein 116


chr11_-_1785190 14.599 NM_001909
CTSD
cathepsin D
chr12_+_12878718 14.562 NM_001130415
APOLD1
apolipoprotein L domain containing 1
chr16_-_58718607 14.487 NM_018231
SLC38A7
solute carrier family 38, member 7
chr7_-_44530178 14.473 NM_015332
NUDCD3
NudC domain containing 3
chr8_+_59465818 14.460 SDCBP
syndecan binding protein (syntenin)
chr22_+_38599026 14.373 NM_001161573
MAFF
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr12_+_50898744 14.316 NM_173602
DIP2B
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr2_-_172864747 14.213


chr18_-_21977785 14.203 NM_080597
OSBPL1A
oxysterol binding protein-like 1A
chr8_+_17780492 14.086 PCM1
pericentriolar material 1
chrX_+_102840412 13.997 NM_001006935
NM_001006937
NM_024863
TCEAL4


transcription elongation factor A (SII)-like 4


chr11_-_6640644 13.846 TPP1
tripeptidyl peptidase I
chr22_+_35695872 13.720 TOM1
target of myb1 (chicken)
chr22_+_42394728 13.570 NM_152613
WBP2NL
WBP2 N-terminal like
chr11_-_1330840 13.569 TOLLIP
toll interacting protein
chr17_+_42422627 13.568 GRN
granulin
chr1_+_236305831 13.549 NM_003272
GPR137B
G protein-coupled receptor 137B
chr4_+_113739203 13.503 NM_001127493
ANK2
ankyrin 2, neuronal
chr3_+_158519714 13.353 NM_001167903
NM_022736
MFSD1

major facilitator superfamily domain containing 1

chr14_-_88459459 13.309 GALC
galactosylceramidase
chr9_+_6757919 13.308 KDM4C
lysine (K)-specific demethylase 4C
chr22_-_21213012 13.149 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr16_-_88923348 13.096 NM_000512
GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chrX_+_100878350 12.976 NM_177948
ARMCX3
armadillo repeat containing, X-linked 3
chr6_-_158589202 12.958 SERAC1
serine active site containing 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.53 5.25e-08 GO:0051179 localization
1.54 1.59e-06 GO:0051234 establishment of localization
1.90 2.20e-06 GO:0051641 cellular localization
1.53 2.71e-06 GO:0006810 transport
9.23 3.48e-06 GO:0015682 ferric iron transport
9.23 3.48e-06 GO:0015988 energy coupled proton transport, against electrochemical gradient
9.23 3.48e-06 GO:0015991 ATP hydrolysis coupled proton transport
9.23 3.48e-06 GO:0033572 transferrin transport
6.73 1.85e-05 GO:0007033 vacuole organization
1.16 2.58e-05 GO:0009987 cellular process
1.81 2.95e-05 GO:0033036 macromolecule localization
1.89 3.71e-05 GO:0051649 establishment of localization in cell
1.87 1.50e-04 GO:0008104 protein localization
5.57 2.59e-04 GO:0015992 proton transport
5.38 4.09e-04 GO:0006818 hydrogen transport
2.00 7.02e-04 GO:0016192 vesicle-mediated transport
2.55 1.21e-03 GO:0071495 cellular response to endogenous stimulus
4.75 2.10e-03 GO:0055072 iron ion homeostasis
7.69 2.43e-03 GO:0007040 lysosome organization
1.91 2.89e-03 GO:0046907 intracellular transport
2.79 4.73e-03 GO:0032868 response to insulin stimulus
2.49 5.97e-03 GO:0032870 cellular response to hormone stimulus
2.12 6.57e-03 GO:0034613 cellular protein localization
4.62 7.18e-03 GO:0006879 cellular iron ion homeostasis
2.10 7.74e-03 GO:0070727 cellular macromolecule localization
4.86 9.66e-03 GO:0006826 iron ion transport
2.37 1.24e-02 GO:0043434 response to peptide hormone stimulus
3.66 1.39e-02 GO:0000041 transition metal ion transport
1.79 1.56e-02 GO:0045184 establishment of protein localization
1.79 1.78e-02 GO:0015031 protein transport
1.75 2.11e-02 GO:0070887 cellular response to chemical stimulus
2.82 2.35e-02 GO:0034220 ion transmembrane transport
2.61 2.41e-02 GO:0006897 endocytosis
2.61 2.41e-02 GO:0010324 membrane invagination
1.46 2.43e-02 GO:0065008 regulation of biological quality
5.13 3.61e-02 GO:0048167 regulation of synaptic plasticity
1.92 3.86e-02 GO:0009725 response to hormone stimulus
1.86 4.57e-02 GO:0009719 response to endogenous stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
4.12 6.50e-17 GO:0005773 vacuole
3.63 2.44e-10 GO:0000323 lytic vacuole
3.63 2.44e-10 GO:0005764 lysosome
4.65 4.80e-10 GO:0005774 vacuolar membrane
4.44 1.66e-09 GO:0044437 vacuolar part
5.19 3.40e-07 GO:0042470 melanosome
5.19 3.40e-07 GO:0048770 pigment granule
2.58 6.48e-07 GO:0005768 endosome
11.54 9.11e-07 GO:0033176 proton-transporting V-type ATPase complex
1.31 1.84e-06 GO:0044444 cytoplasmic part
2.03 1.22e-05 GO:0031982 vesicle
4.05 2.96e-05 GO:0005765 lysosomal membrane
2.00 4.21e-05 GO:0031410 cytoplasmic vesicle
3.94 4.62e-05 GO:0005770 late endosome
1.20 5.31e-05 GO:0005737 cytoplasm
6.44 5.95e-05 GO:0016469 proton-transporting two-sector ATPase complex
3.55 7.63e-05 GO:0005769 early endosome
1.18 1.93e-04 GO:0043227 membrane-bounded organelle
1.95 2.35e-04 GO:0031988 membrane-bounded vesicle
1.18 2.44e-04 GO:0043231 intracellular membrane-bounded organelle
1.96 2.76e-04 GO:0016023 cytoplasmic membrane-bounded vesicle
2.62 1.14e-03 GO:0010008 endosome membrane
2.60 1.34e-03 GO:0044440 endosomal part
1.12 1.58e-03 GO:0044424 intracellular part
1.12 1.79e-03 GO:0005622 intracellular
8.97 1.92e-03 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain
1.15 2.69e-03 GO:0043226 organelle
1.14 4.25e-03 GO:0043229 intracellular organelle
12.82 5.39e-03 GO:0033180 proton-transporting V-type ATPase, V1 domain
15.38 1.60e-02 GO:0033179 proton-transporting V-type ATPase, V0 domain
1.72 1.61e-02 GO:0005624 membrane fraction
1.70 2.08e-02 GO:0005626 insoluble fraction

Gene overrepresentation in function category:

enrichment   p-value GO term description
11.54 8.10e-06 GO:0046961 proton-transporting ATPase activity, rotational mechanism
7.69 1.39e-04 GO:0019829 cation-transporting ATPase activity
3.73 2.40e-03 GO:0042626 ATPase activity, coupled to transmembrane movement of substances
3.69 2.75e-03 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
3.69 2.75e-03 GO:0043492 ATPase activity, coupled to movement of substances
1.20 2.80e-03 GO:0005515 protein binding
4.35 3.25e-03 GO:0042625 ATPase activity, coupled to transmembrane movement of ions
2.24 6.45e-03 GO:0022804 active transmembrane transporter activity
3.39 8.47e-03 GO:0015399 primary active transmembrane transporter activity
3.39 8.47e-03 GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity
3.33 3.36e-02 GO:0015078 hydrogen ion transmembrane transporter activity