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Motif ID: TP53.p2

Z-value: 2.109

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_-_64455184	39.376		PPIB	peptidylprolyl isomerase B (cyclophilin B)
chr15_-_64455206	37.642		PPIB	peptidylprolyl isomerase B (cyclophilin B)
chr15_-_64455158	36.840		PPIB	peptidylprolyl isomerase B (cyclophilin B)
chr15_-_64455190	36.717		PPIB	peptidylprolyl isomerase B (cyclophilin B)
chr15_-_64455299	35.464	NM_000942	PPIB	peptidylprolyl isomerase B (cyclophilin B)
chr6_+_36644236	34.946	NM_001220777 NM_078467	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr20_-_32891075	32.064	NM_000687	AHCY	adenosylhomocysteinase
chr1_+_156052330	30.992		LMNA	lamin A/C
chr17_+_76210329	28.562		BIRC5	baculoviral IAP repeat containing 5
chr2_-_74756824	27.604		AUP1	ancient ubiquitous protein 1
chr17_+_76210276	25.226	NM_001012270 NM_001012271 NM_001168	BIRC5	baculoviral IAP repeat containing 5
chr6_-_138428477	25.028	NM_022121	PERP	PERP, TP53 apoptosis effector
chr12_+_56498324	24.855		PA2G4	proliferation-associated 2G4, 38kDa
chr20_+_35234152	24.576		C20orf24	chromosome 20 open reading frame 24
chr6_-_30712294	24.416	NM_003897	IER3	immediate early response 3
chr4_-_10118358	24.234		WDR1	WD repeat domain 1
chr1_+_224544550	23.621		CNIH4	cornichon homolog 4 (Drosophila)
chr3_+_127771287	23.326		SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)
chr12_+_56498347	23.135		PA2G4	proliferation-associated 2G4, 38kDa
chr4_-_10118378	23.040		WDR1	WD repeat domain 1
chr3_+_23851933	23.019	NM_001202476	UBE2E1	ubiquitin-conjugating enzyme E2E 1
chr19_-_2456954	22.999	NM_032737	LMNB2	lamin B2
chr1_+_203830732	22.775	NM_003094	SNRPE	small nuclear ribonucleoprotein polypeptide E
chr20_+_35234077	22.545	NM_001199534 NM_018840 NM_199483	C20orf24	chromosome 20 open reading frame 24
chr9_+_116037913	22.489	NM_001244926 NM_004697	PRPF4	PRP4 pre-mRNA processing factor 4 homolog (yeast)
chr20_+_35234210	22.162		C20orf24	chromosome 20 open reading frame 24
chr5_-_175788714	22.116	NM_001079684 NM_001079685 NM_020444	KIAA1191	KIAA1191
chr1_+_224544590	21.696	NM_014184	CNIH4	cornichon homolog 4 (Drosophila)
chr18_+_57567191	21.599	NM_021127	PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1
chrX_+_154114609	21.520	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated 2 coagulation factor VIII-associated 3 coagulation factor VIII-associated 1
chr3_+_160118346	21.135	NM_005496	SMC4	structural maintenance of chromosomes 4
chr1_+_203830763	21.020		SNRPE	small nuclear ribonucleoprotein polypeptide E
chr3_+_127771126	20.478	NM_013336	SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)
chr10_-_135186836	20.454	NM_004092	ECHS1	enoyl CoA hydratase, short chain, 1, mitochondrial
chr20_-_47804675	19.939		STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)
chr22_-_18257221	19.436		BID	BH3 interacting domain death agonist
chr4_+_41937105	19.212	NM_018126	TMEM33	transmembrane protein 33
chr11_+_74660290	18.861	NM_014752	LOC653566 SPCS2	signal peptidase complex subunit 2 homolog pseudogene signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr10_+_120863558	18.706		FAM45A	family with sequence similarity 45, member A
chrX_+_154611748	18.416	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated 2 coagulation factor VIII-associated 3 coagulation factor VIII-associated 1
chrX_-_154688260	18.305	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated 2 coagulation factor VIII-associated 3 coagulation factor VIII-associated 1
chr2_-_47168870	18.227		MCFD2	multiple coagulation factor deficiency 2
chr1_-_156710902	18.082	NM_024540 NM_145729	MRPL24	mitochondrial ribosomal protein L24
chr7_+_101006121	17.838	NM_133457	EMID2	EMI domain containing 2
chrX_-_153285262	17.619		IRAK1	interleukin-1 receptor-associated kinase 1
chr2_-_47168902	17.349	NM_001171508 NM_001171511	MCFD2	multiple coagulation factor deficiency 2
chr1_+_224544597	17.297		CNIH4	cornichon homolog 4 (Drosophila)
chr18_+_34409058	17.217	NM_020776	KIAA1328	KIAA1328
chr16_-_31106049	17.016		VKORC1	vitamin K epoxide reductase complex, subunit 1
chr9_-_138853146	16.788	NM_016172	UBAC1	UBA domain containing 1
chr22_-_18257194	16.771		BID	BH3 interacting domain death agonist
chr12_+_56498414	16.757		PA2G4	proliferation-associated 2G4, 38kDa
chr20_-_47804903	16.605	NM_001037328 NM_004602 NM_017452 NM_017453 NM_017454	STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)
chr11_+_74660317	16.343		SPCS2	signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr1_+_41444968	16.263	NM_001905	CTPS	CTP synthase
chr5_+_72794273	16.184		BTF3	basic transcription factor 3
chr4_-_10118296	15.922		WDR1	WD repeat domain 1
chr5_+_72794247	15.666	NM_001037637 NM_001207	BTF3	basic transcription factor 3
chr4_-_10118286	15.316
chr20_-_5100443	15.112	NM_182649	PCNA	proliferating cell nuclear antigen
chr11_+_74660321	15.058		SPCS2	signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr10_+_120863610	15.008	NM_207009	FAM45A	family with sequence similarity 45, member A
chr1_+_43148359	14.763		YBX1	Y box binding protein 1
chr3_-_113465101	14.758	NM_025146	NAA50	N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr16_-_31106125	14.722	NM_024006 NM_206824	VKORC1	vitamin K epoxide reductase complex, subunit 1
chrX_-_109561314	14.470	NM_001025580 NM_015365	AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr9_-_138853007	14.202		UBAC1	UBA domain containing 1
chr12_+_56498365	14.168		PA2G4	proliferation-associated 2G4, 38kDa
chr9_+_37422645	14.113	NM_012203	GRHPR	glyoxylate reductase/hydroxypyruvate reductase
chr9_-_104160876	14.011	NM_019051	MRPL50	mitochondrial ribosomal protein L50
chr8_-_22926490	13.675	NM_003842 NM_147187	TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b
chr20_-_1373702	13.622		FKBP1A-SDCBP2 FKBP1A	FKBP1A-SDCBP2 readthrough (non-protein coding) FK506 binding protein 1A, 12kDa
chr12_+_56498334	13.536		PA2G4	proliferation-associated 2G4, 38kDa
chr7_-_74867340	13.008	NM_001145064	GTF2IP1 GATSL2	general transcription factor IIi, pseudogene 1 GATS protein-like 2
chr4_-_10118444	12.896		WDR1	WD repeat domain 1
chr7_+_98972351	12.855		ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa
chr4_-_47916498	12.764	NM_152995	NFXL1	nuclear transcription factor, X-box binding-like 1
chr18_+_12947972	12.521	NM_001013437 NM_031216	SEH1L	SEH1-like (S. cerevisiae)
chr10_+_120863626	12.318		FAM45A FAM45B	family with sequence similarity 45, member A family with sequence similarity 45, member A pseudogene
chr1_-_10532603	12.261	NM_004401 NM_213566	DFFA	DNA fragmentation factor, 45kDa, alpha polypeptide
chr2_-_198364997	11.958	NM_199440	HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr1_+_43824598	11.845	NM_001255	CDC20	cell division cycle 20 homolog (S. cerevisiae)
chr19_+_17970670	11.785	NM_000980	RPL18A	ribosomal protein L18a
chr5_+_162864571	11.750	NM_004060 NM_199246	CCNG1	cyclin G1
chr7_-_42971730	11.746		PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2
chr22_-_18257160	11.594		BID	BH3 interacting domain death agonist
chr7_+_140396463	11.529	NM_004546	NDUFB2	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr1_-_93645903	11.519		TMED5	transmembrane emp24 protein transport domain containing 5
chr1_-_93646245	11.321	NM_001167830 NM_016040	TMED5	transmembrane emp24 protein transport domain containing 5
chr6_-_101329197	11.308	NM_006828 NM_022091	ASCC3	activating signal cointegrator 1 complex subunit 3
chrX_+_40440229	11.103		ATP6AP2	ATPase, H+ transporting, lysosomal accessory protein 2
chr11_-_47399903	11.090
chr19_+_42364322	11.082		RPS19	ribosomal protein S19
chr19_+_38865424	11.015		PSMD8	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr12_+_12966249	10.994	NM_016355 NM_201224	DDX47	DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chrX_+_38663503	10.991		MID1IP1	MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr18_+_9913954	10.943	NM_003574 NM_194434	VAPA	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr5_+_135364583	10.907	NM_000358	TGFBI	transforming growth factor, beta-induced, 68kDa
chr9_+_116037955	10.875		PRPF4	PRP4 pre-mRNA processing factor 4 homolog (yeast)
chr22_-_18257238	10.842	NM_001196 NM_001244569 NM_001244570 NM_197967 NM_001244567	BID	BH3 interacting domain death agonist
chr7_-_132766834	10.764		CHCHD3	coiled-coil-helix-coiled-coil-helix domain containing 3
chrX_+_40440261	10.752		ATP6AP2	ATPase, H+ transporting, lysosomal accessory protein 2
chr15_+_40453209	10.749	NM_001211	BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)
chr4_-_10118500	10.680	NM_005112 NM_017491	WDR1	WD repeat domain 1
chr8_-_146017774	10.626		RPL8	ribosomal protein L8
chr15_-_63449479	10.615	NM_015920	RPS27L	ribosomal protein S27-like
chr16_-_31106093	10.600		VKORC1	vitamin K epoxide reductase complex, subunit 1
chr12_+_53895376	10.589	NM_134324	TARBP2	TAR (HIV-1) RNA binding protein 2
chr2_+_169312793	10.578	NM_203463	CERS6	ceramide synthase 6
chr16_+_447175	10.405	NM_005009	NME4	non-metastatic cells 4, protein expressed in
chr9_+_80911990	10.398	NM_021154 NM_058179	PSAT1	phosphoserine aminotransferase 1
chr20_-_33543582	10.354	NM_000178	GSS	glutathione synthetase
chr15_-_90777144	10.248		CIB1	calcium and integrin binding 1 (calmyrin)
chr1_+_223900212	10.241		CAPN2	calpain 2, (m/II) large subunit
chr11_-_47400096	10.086	NM_001080547 NM_003120	SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr5_-_176831385	9.976		F12	coagulation factor XII (Hageman factor)
chr7_-_132766697	9.960	NM_017812	CHCHD3	coiled-coil-helix-coiled-coil-helix domain containing 3
chr12_+_109535377	9.801	NM_080911	UNG	uracil-DNA glycosylase
chr18_+_9914032	9.764		VAPA	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr2_-_74756755	9.757		AUP1	ancient ubiquitous protein 1
chr12_+_116997185	9.710	NM_001085481	MAP1LC3B2	microtubule-associated protein 1 light chain 3 beta 2
chr20_-_33543548	9.683		GSS	glutathione synthetase
chr19_+_3572903	9.540	NM_006339	HMG20B	high mobility group 20B
chr2_+_198365012	9.507		HSPE1	heat shock 10kDa protein 1 (chaperonin 10)
chr12_+_53894704	9.488	NM_004178 NM_134323	TARBP2	TAR (HIV-1) RNA binding protein 2
chr1_-_38412725	9.476	NM_005540	INPP5B	inositol polyphosphate-5-phosphatase, 75kDa
chr2_-_24307179	9.458	NM_001206802	TP53I3	tumor protein p53 inducible protein 3
chr3_-_113464991	9.421		NAA50	N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr16_+_67880784	9.415	NM_005796	NUTF2	nuclear transport factor 2
chr19_+_3572950	9.412		HMG20B	high mobility group 20B
chr12_-_76424474	9.314		PHLDA1	pleckstrin homology-like domain, family A, member 1
chrX_+_40440145	9.280	NM_005765	ATP6AP2	ATPase, H+ transporting, lysosomal accessory protein 2
chrX_-_109561298	9.218		AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr12_-_122712019	9.206	NM_019887 NM_138929	DIABLO	diablo, IAP-binding mitochondrial protein
chr15_-_34635306	9.204	NM_018648	NOP10	NOP10 ribonucleoprotein homolog (yeast)
chr12_-_54070108	9.171	NM_005176	ATP5G2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr12_+_53645985	9.128		MFSD5	major facilitator superfamily domain containing 5
chr7_+_100770378	9.099	NM_000602 NM_001165413	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr7_+_98972326	8.935		ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa
chr19_+_42364262	8.900		RPS19	ribosomal protein S19
chr1_+_203830723	8.763		SNRPE	small nuclear ribonucleoprotein polypeptide E
chr19_+_3572958	8.724		HMG20B	high mobility group 20B
chr12_+_53645869	8.653	NM_032889	MFSD5	major facilitator superfamily domain containing 5
chr2_+_113403433	8.517	NM_005415	SLC20A1	solute carrier family 20 (phosphate transporter), member 1
chr3_+_196466724	8.495	NM_002577	PAK2	p21 protein (Cdc42/Rac)-activated kinase 2
chr10_-_95241943	8.488	NM_013451 NM_133337	MYOF	myoferlin
chr20_-_1373744	8.371	NM_000801 NM_001199786 NM_054014	FKBP1A	FK506 binding protein 1A, 12kDa
chr6_+_34204690	8.330		HMGA1	high mobility group AT-hook 1
chr22_-_36925212	8.316		EIF3D	eukaryotic translation initiation factor 3, subunit D
chr8_-_146017716	8.303	NM_033301	RPL8	ribosomal protein L8
chr10_+_88854900	8.280	NM_019054	FAM35A	family with sequence similarity 35, member A
chr11_+_125439373	8.276		EI24	etoposide induced 2.4 mRNA
chr2_+_69969250	8.244		ANXA4	annexin A4
chr3_+_183892569	8.111	NM_001025205 NM_004068	AP2M1	adaptor-related protein complex 2, mu 1 subunit
chr5_-_179233772	8.081	NM_014275	MGAT4B	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr20_-_48732479	8.080	NM_022442 NM_021988 NM_199144	UBE2V1	ubiquitin-conjugating enzyme E2 variant 1
chr20_+_3869485	7.962	NM_024960	PANK2	pantothenate kinase 2
chr1_+_223900226	7.916		CAPN2	calpain 2, (m/II) large subunit
chr11_+_64889802	7.897		MRPL49	mitochondrial ribosomal protein L49
chr3_+_183892647	7.860		AP2M1	adaptor-related protein complex 2, mu 1 subunit
chr21_-_44846927	7.833	NM_173354	SIK1	salt-inducible kinase 1
chr5_-_176778683	7.805	NM_006816	LMAN2	lectin, mannose-binding 2
chr7_-_42971779	7.747	NM_002787	PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2
chr11_+_125439363	7.718		EI24	etoposide induced 2.4 mRNA
chr7_+_72569025	7.639		GTF2IP1	general transcription factor IIi, pseudogene 1
chr8_-_22926406	7.635		TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b
chr11_+_64889699	7.626	NM_004927	MRPL49	mitochondrial ribosomal protein L49
chr6_-_114292312	7.619	NM_001527	HDAC2	histone deacetylase 2
chr1_-_153508495	7.546		S100A6	S100 calcium binding protein A6
chr12_+_53895065	7.481		TARBP2	TAR (HIV-1) RNA binding protein 2
chrX_+_38663450	7.464		MID1IP1	MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr10_-_5931800	7.417	NM_001009941 NM_001009943 NM_019046	ANKRD16	ankyrin repeat domain 16
chr7_+_116166346	7.371	NM_001172896 NM_001172897	CAV1	caveolin 1, caveolae protein, 22kDa
chr18_-_34408699	7.316		TPGS2	tubulin polyglutamylase complex subunit 2
chr20_-_61847446	7.300	NM_017798	YTHDF1	YTH domain family, member 1
chr3_+_183892668	7.272		AP2M1	adaptor-related protein complex 2, mu 1 subunit
chr1_-_156710855	7.201		MRPL24	mitochondrial ribosomal protein L24
chr20_+_3869593	7.095	NM_153638	PANK2	pantothenate kinase 2
chr12_+_53645906	7.060		MFSD5	major facilitator superfamily domain containing 5
chr3_+_183892662	7.017		AP2M1	adaptor-related protein complex 2, mu 1 subunit
chr2_-_120980971	6.891	NM_024121	TMEM185B	transmembrane protein 185B
chr1_+_32645322	6.856	NM_175852	TXLNA	taxilin alpha
chrX_+_38663072	6.840	NM_021242	MID1IP1	MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr12_-_6451156	6.809	NM_001065	TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A
chr1_-_6453362	6.764		ACOT7	acyl-CoA thioesterase 7
chr1_-_54411245	6.707	NM_016126	HSPB11	heat shock protein family B (small), member 11
chr17_-_80407601	6.659	NM_001193655	C17orf62	chromosome 17 open reading frame 62
chr15_-_65477441	6.637	NM_006660	CLPX	ClpX caseinolytic peptidase X homolog (E. coli)
chr15_-_65477645	6.615		CLPX	ClpX caseinolytic peptidase X homolog (E. coli)
chr19_-_2051222	6.612	NM_017572 NM_199054	MKNK2	MAP kinase interacting serine/threonine kinase 2
chr11_+_125439294	6.549	NM_001007277 NM_004879	EI24	etoposide induced 2.4 mRNA
chr5_+_141348692	6.538	NM_183401	RNF14	ring finger protein 14
chr2_-_74756838	6.445		AUP1	ancient ubiquitous protein 1
chr2_-_47142880	6.432		MCFD2	multiple coagulation factor deficiency 2
chr3_-_49066858	6.417	NM_000884	IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2
chr6_+_24403144	6.387	NM_020662	MRS2	MRS2 magnesium homeostasis factor homolog (S. cerevisiae)
chr11_+_9685624	6.345	NM_015055	SWAP70	SWAP switching B-cell complex 70kDa subunit
chr1_+_215178884	6.330	NM_001017424	KCNK2	potassium channel, subfamily K, member 2
chr1_-_153508463	6.264		S100A6	S100 calcium binding protein A6
chr14_-_68141328	6.237	NM_006370	VTI1B	vesicle transport through interaction with t-SNAREs homolog 1B (yeast)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.43	1.38e-09	GO:0008152	metabolic process
1.47	3.28e-09	GO:0044237	cellular metabolic process
1.22	4.74e-07	GO:0009987	cellular process
1.41	1.13e-06	GO:0044238	primary metabolic process
2.25	1.72e-05	GO:0042981	regulation of apoptosis
2.24	2.32e-05	GO:0043067	regulation of programmed cell death
2.20	4.02e-05	GO:0010941	regulation of cell death
1.68	1.83e-04	GO:0048522	positive regulation of cellular process
1.61	6.04e-04	GO:0048518	positive regulation of biological process
1.43	1.07e-03	GO:0044260	cellular macromolecule metabolic process
1.64	1.28e-03	GO:0044249	cellular biosynthetic process
1.62	1.41e-03	GO:0009058	biosynthetic process
1.38	2.10e-03	GO:0043170	macromolecule metabolic process
1.51	7.20e-03	GO:0019538	protein metabolic process
2.73	1.06e-02	GO:0044271	cellular nitrogen compound biosynthetic process
4.17	1.17e-02	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
2.77	1.24e-02	GO:0006917	induction of apoptosis
1.56	1.27e-02	GO:0044267	cellular protein metabolic process
2.76	1.30e-02	GO:0012502	induction of programmed cell death
1.66	1.88e-02	GO:0044281	small molecule metabolic process
1.46	2.15e-02	GO:0006807	nitrogen compound metabolic process
1.51	2.28e-02	GO:0071841	cellular component organization or biogenesis at cellular level
3.63	3.00e-02	GO:0031400	negative regulation of protein modification process
2.36	3.28e-02	GO:0043065	positive regulation of apoptosis
3.81	3.35e-02	GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade
2.34	3.69e-02	GO:0043068	positive regulation of programmed cell death
1.42	4.17e-02	GO:0071840	cellular component organization or biogenesis
1.50	4.53e-02	GO:0071842	cellular component organization at cellular level
2.09	4.72e-02	GO:0006915	apoptosis

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.61	7.38e-17	GO:0044444	cytoplasmic part
1.43	1.31e-15	GO:0005737	cytoplasm
1.24	2.60e-10	GO:0044424	intracellular part
2.01	5.62e-10	GO:0005829	cytosol
1.21	7.70e-09	GO:0005622	intracellular
1.45	1.59e-07	GO:0044446	intracellular organelle part
1.44	1.78e-07	GO:0044422	organelle part
1.28	8.09e-07	GO:0043227	membrane-bounded organelle
2.09	1.11e-06	GO:0005739	mitochondrion
1.28	1.26e-06	GO:0043231	intracellular membrane-bounded organelle
1.24	2.84e-06	GO:0043226	organelle
2.53	3.12e-06	GO:0031967	organelle envelope
1.24	3.99e-06	GO:0043229	intracellular organelle
2.49	5.33e-06	GO:0031975	envelope
1.48	3.14e-04	GO:0032991	macromolecular complex
1.64	6.34e-04	GO:0031090	organelle membrane
5.06	1.17e-03	GO:0042470	melanosome
5.06	1.17e-03	GO:0048770	pigment granule
1.59	1.25e-03	GO:0031974	membrane-enclosed lumen
2.48	2.14e-03	GO:0005740	mitochondrial envelope
2.19	2.16e-03	GO:0044429	mitochondrial part
2.66	6.23e-03	GO:0019866	organelle inner membrane
2.41	7.17e-03	GO:0031966	mitochondrial membrane
1.52	1.11e-02	GO:0043233	organelle lumen
1.54	1.19e-02	GO:0044428	nuclear part
1.50	2.68e-02	GO:0070013	intracellular organelle lumen
1.60	3.50e-02	GO:0012505	endomembrane system
1.41	3.91e-02	GO:0043234	protein complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.39	3.07e-09	GO:0005515	protein binding
1.14	1.65e-03	GO:0005488	binding
1.29	1.60e-02	GO:0003824	catalytic activity