Motif ID: UGUGCUU

Z-value: 2.998


Mature miRNA associated with seed UGUGCUU:

NamemiRBase Accession
hsa-miR-218 MIMAT0000275



Activity profile for motif UGUGCUU.

activity profile for motif UGUGCUU


Sorted Z-values histogram for motif UGUGCUU

Sorted Z-values for motif UGUGCUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UGUGCUU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_130374466 62.415 NM_001032221
NM_003165
STXBP1

syntaxin binding protein 1

chr16_+_58498725 58.575 NM_022910
NDRG4
NDRG family member 4
chr16_+_58534045 56.708 NM_001242833
NM_001242834
NM_001242835
NM_001242836
NDRG4



NDRG family member 4



chr16_+_58497993 52.823 NM_001130487
NDRG4
NDRG family member 4
chr15_+_74422589 50.192 NM_001130138
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr16_+_58497548 49.456 NM_020465
NDRG4
NDRG family member 4
chr12_-_16760935 47.920 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr18_+_21594349 47.533 NM_001135993
NM_001243425
TTC39C

tetratricopeptide repeat domain 39C

chr7_-_37393271 47.019 NM_001206482
ELMO1
engulfment and cell motility 1
chr12_-_16759531 46.481 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr15_+_74422742 45.649 NM_020851
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr15_+_74421698 45.602 NM_001130136
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr14_+_92790151 45.456 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr15_+_74421986 45.389 NM_001130137
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr4_+_158141735 43.780 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr1_-_149889362 43.063 NM_014849
SV2A
synaptic vesicle glycoprotein 2A
chr9_-_93405066 41.364 NM_017594
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr5_-_176057324 41.186 NM_001001502
NM_003085
SNCB

synuclein, beta

chr7_+_153584383 40.385 NM_001039350
DPP6
dipeptidyl-peptidase 6
chr11_-_134281725 39.080 NM_018644
NM_054025
B3GAT1

beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

chr11_+_62475113 38.637 NM_012202
GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr19_+_19322763 37.937 NM_004386
NCAN
neurocan
chr3_+_11034419 37.611 NM_003042
SLC6A1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr14_+_92789536 37.532 NM_153647
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr22_-_39548448 36.970 NM_175709
CBX7
chromobox homolog 7
chr12_+_79257772 36.048 NM_001135805
SYT1
synaptotagmin I
chr20_-_4804067 35.684 NM_014737
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr7_+_153749740 35.520 NM_130797
DPP6
dipeptidyl-peptidase 6
chr2_+_231729501 35.510 NM_001012514
NM_001012516
NM_030926
ITM2C


integral membrane protein 2C


chr15_+_91643429 35.057 NM_014848
SV2B
synaptic vesicle glycoprotein 2B
chr7_-_37024664 34.918 NM_001039459
ELMO1
engulfment and cell motility 1
chr7_-_37488554 34.436 NM_014800
ELMO1
engulfment and cell motility 1
chr5_-_11903964 34.417 NM_001332
CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr11_+_63448868 33.661 NM_006054
NM_201428
NM_201429
NM_201430
RTN3



reticulon 3



chr12_+_79439432 33.327 NM_001135806
SYT1
synaptotagmin I
chr3_+_167453431 33.041 NM_001122752
NM_005025
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr5_-_88179278 32.962 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr7_-_37488894 32.764 NM_001206480
ELMO1
engulfment and cell motility 1
chr15_+_91643181 32.345 NM_001167580
SV2B
synaptic vesicle glycoprotein 2B
chr12_+_79258448 32.266 NM_005639
SYT1
synaptotagmin I
chr20_+_34742656 32.255 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr13_+_27131799 32.159 NM_006646
WASF3
WAS protein family, member 3
chr20_-_4795768 31.645 NM_170774
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr3_+_49591897 31.644 NM_003458
BSN
bassoon (presynaptic cytomatrix protein)
chr16_+_22825806 31.277 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr12_-_131002409 30.366 NM_015347
RIMBP2
RIMS binding protein 2
chr3_+_238274 30.335 NM_001253387
NM_006614
CHL1

cell adhesion molecule with homology to L1CAM (close homolog of L1)

chr18_+_21572736 29.977 NM_153211
TTC39C
tetratricopeptide repeat domain 39C
chr1_-_52831817 28.873 NM_032449
CC2D1B
coiled-coil and C2 domain containing 1B
chr7_-_79082870 28.227 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_-_2334887 28.190 NM_015025
MYT1L
myelin transcription factor 1-like
chr10_-_75910525 27.722 NM_012095
NM_207012
AP3M1

adaptor-related protein complex 3, mu 1 subunit

chr14_-_51562421 27.334 NM_015163
NM_052978
TRIM9

tripartite motif containing 9

chr14_+_92788924 27.243 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr20_+_34700257 27.133 NM_177996
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr1_-_21995793 26.673 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr6_+_101846860 25.035 NM_001166247
NM_021956
NM_175768
GRIK2


glutamate receptor, ionotropic, kainate 2


chr6_+_69344939 24.792 NM_001704
BAI3
brain-specific angiogenesis inhibitor 3
chr19_+_32896515 24.656 NM_001172774
DPY19L3
dpy-19-like 3 (C. elegans)
chr19_-_38720312 24.447 NM_001135156
DPF1
D4, zinc and double PHD fingers family 1
chr2_-_26205437 24.334 NM_002254
KIF3C
kinesin family member 3C
chr1_-_154155698 23.947 NM_001043351
NM_001043352
NM_001043353
NM_153649
TPM3



tropomyosin 3



chr13_-_36705513 23.651 NM_004734
DCLK1
doublecortin-like kinase 1
chr7_+_154002194 23.625 NM_001936
DPP6
dipeptidyl-peptidase 6
chr7_+_97361270 23.142 NM_003182
NM_013996
NM_013997
NM_013998
TAC1



tachykinin, precursor 1



chr2_-_152830448 23.021 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr20_+_43991739 23.015 NM_001099791
NM_033542
SYS1-DBNDD2
SYS1

SYS1-DBNDD2 readthrough
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)

chr1_-_41131323 22.758 NM_014747
RIMS3
regulating synaptic membrane exocytosis 3
chr1_-_21978287 22.739 NM_001145658
RAP1GAP
RAP1 GTPase activating protein
chr11_-_70507911 22.688 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr7_-_103629962 22.492 NM_005045
NM_173054
RELN

reelin

chr7_+_45614081 22.155 NM_021116
ADCY1
adenylate cyclase 1 (brain)
chr9_+_34958171 21.942 NM_015297
KIAA1045
KIAA1045
chr11_-_45307617 21.239 NM_001247987
NM_020826
SYT13

synaptotagmin XIII

chr17_+_53342320 21.184 NM_002126
HLF
hepatic leukemia factor
chr12_+_78225068 20.584 NM_014903
NAV3
neuron navigator 3
chr7_-_17980102 20.185 NM_015132
SNX13
sorting nexin 13
chr18_-_6414900 20.020 NM_173464
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr15_+_75287829 19.748 NM_001178111
NM_001178112
NM_138967
SCAMP5


secretory carrier membrane protein 5


chr4_-_99579540 19.682 NM_005723
TSPAN5
tetraspanin 5
chr2_+_113033146 19.508 NM_198581
ZC3H6
zinc finger CCCH-type containing 6
chr19_-_4559713 19.395 NM_032108
SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr2_-_152955208 18.768 NM_001005746
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr18_+_55102777 18.681 NM_004852
ONECUT2
one cut homeobox 2
chr11_-_70935807 18.520 NM_012309
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr6_+_31126114 18.442 NM_001077511
NM_007109
TCF19

transcription factor 19

chr10_-_97321094 18.322 NM_015385
NM_024991
SORBS1

sorbin and SH3 domain containing 1

chr3_+_23987514 18.147 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr19_-_17799005 17.862 NM_001080421
UNC13A
unc-13 homolog A (C. elegans)
chr5_+_67511578 17.763 NM_181523
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr13_-_36429798 17.733 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr6_+_150920998 17.670 NM_001029884
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr5_-_115910406 17.644 NM_020796
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr16_-_68482373 17.598 NM_018667
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr16_+_1756161 17.552 NM_001040439
NM_015133
MAPK8IP3

mitogen-activated protein kinase 8 interacting protein 3

chr1_-_200992824 17.521 NM_001252100
NM_001252102
NM_001252103
NM_017596
KIF21B



kinesin family member 21B



chr6_+_72922513 17.410 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr19_+_34112854 17.387 NM_001127895
NM_001127896
CHST8

carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8

chr3_+_33318911 16.945 NM_012157
NM_001171713
FBXL2

F-box and leucine-rich repeat protein 2

chr9_-_91793681 16.857 NM_016848
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr2_-_152955502 16.857 NM_000726
NM_001145798
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr1_+_99729847 16.701 NM_001166252
NM_014839
LPPR4

lipid phosphate phosphatase-related protein type 4

chr15_+_59063389 16.416 NM_001040450
NM_001040453
FAM63B

family with sequence similarity 63, member B

chr8_-_18871163 16.296 NM_015310
PSD3
pleckstrin and Sec7 domain containing 3
chrX_+_153665258 16.263 NM_001493
GDI1
GDP dissociation inhibitor 1
chr5_+_67584251 15.958 NM_181524
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr8_-_56685869 15.841 NM_152417
TMEM68
transmembrane protein 68
chr14_-_73360792 15.786 NM_012074
DPF3
D4, zinc and double PHD fingers, family 3
chr14_+_90863302 15.632 NM_006888
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr12_+_50451486 15.546 NM_001095
NM_020039
ACCN2

amiloride-sensitive cation channel 2, neuronal

chr13_-_30424795 15.523 NM_007106
UBL3
ubiquitin-like 3
chr13_+_35516390 15.393 NM_015678
NBEA
neurobeachin
chr7_-_22396511 15.376 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr2_-_73298815 15.168 NM_144579
SFXN5
sideroflexin 5
chr3_+_32148000 15.159 NM_015141
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr4_-_164253946 15.056 NM_000909
NPY1R
neuropeptide Y receptor Y1
chr17_+_14204326 15.015 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr2_+_236402685 14.889 NM_001037131
NM_001244888
NM_014914
AGAP1


ArfGAP with GTPase domain, ankyrin repeat and PH domain 1


chr2_+_173686314 14.803 NM_001100397
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr2_+_173600519 14.793 NM_007023
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr5_-_88199868 14.651 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr3_-_56502364 14.479 NM_015576
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr11_+_111473099 14.347 NM_015191
SIK2
salt-inducible kinase 2
chr4_-_176734181 14.319 NM_201591
GPM6A
glycoprotein M6A
chr19_-_14316980 14.301 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr19_-_38714781 14.216 NM_001135155
NM_004647
DPF1

D4, zinc and double PHD fingers family 1

chr1_-_6321034 14.158 NM_207370
GPR153
G protein-coupled receptor 153
chr8_+_28559143 14.153 NM_001440
EXTL3
exostoses (multiple)-like 3
chr7_+_138916230 14.122 NM_173569
UBN2
ubinuclein 2
chr19_-_4723814 14.119 NM_139159
DPP9
dipeptidyl-peptidase 9
chr8_-_66753968 14.041 NM_001242318
PDE7A
phosphodiesterase 7A
chr5_+_76506705 13.815 NM_001029851
NM_001029852
NM_001029853
NM_001029854
NM_003719
PDE8B




phosphodiesterase 8B




chr2_-_73496595 13.794 NM_001080410
FBXO41
F-box protein 41
chr20_-_47894591 13.792 NM_021035
ZNFX1
zinc finger, NFX1-type containing 1
chr10_-_21463019 13.721 NM_001173484
NM_213569
NEBL

nebulette

chr4_-_176923572 13.712 NM_005277
NM_201592
GPM6A

glycoprotein M6A

chr17_+_36507708 13.698 NM_014598
SOCS7
suppressor of cytokine signaling 7
chr6_+_30594607 13.463 NM_024909
NM_001031722
NM_001190724
ATAT1


alpha tubulin acetyltransferase 1


chr4_-_122872908 13.270 NM_001130698
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr5_+_173472692 13.255 NM_015980
HMP19
HMP19 protein
chr15_-_52861177 13.186 NM_006628
ARPP19
cAMP-regulated phosphoprotein, 19kDa
chr13_+_103451398 13.138 NM_001159596
NM_017693
BIVM

basic, immunoglobulin-like variable motif containing

chr12_+_32654976 12.850 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr10_-_120514669 12.841 NM_153810
C10orf46
chromosome 10 open reading frame 46
chr9_-_123476578 12.761 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr18_-_53255734 12.581 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr8_-_18666295 12.399 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr11_-_73472057 12.379 NM_001243718
NM_002869
NM_198896
RAB6A


RAB6A, member RAS oncogene family


chr18_-_11148760 12.257 NM_022068
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr10_-_104473957 12.231 NM_004311
ARL3
ADP-ribosylation factor-like 3
chr1_-_109584589 12.003 NM_001142550
NM_001142551
NM_014969
WDR47


WD repeat domain 47


chr3_+_123813527 11.984 NM_001024660
NM_003947
KALRN

kalirin, RhoGEF kinase

chr8_-_41754244 11.700 NM_001142446
ANK1
ankyrin 1, erythrocytic
chr5_-_93447237 11.675 NM_001163417
NM_001163418
NM_032042
FAM172A


family with sequence similarity 172, member A


chrX_-_153236621 11.601 NM_005334
HCFC1
host cell factor C1 (VP16-accessory protein)
chr3_+_39093480 11.558 NM_020839
WDR48
WD repeat domain 48
chr16_+_19535178 11.472 NM_001199022
NM_014711
CCP110

centriolar coiled coil protein 110kDa

chr15_-_26874236 11.432 NM_001191321
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr2_-_213403280 11.415 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr6_+_72926144 11.007 NM_001168409
RIMS1
regulating synaptic membrane exocytosis 1
chr12_+_72666462 10.977 NM_013381
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr5_-_160975124 10.957 NM_000813
NM_021911
GABRB2

gamma-aminobutyric acid (GABA) A receptor, beta 2

chr16_-_62070738 10.864 NM_001796
CDH8
cadherin 8, type 2
chr1_+_53192021 10.704 NM_024646
ZYG11B
zyg-11 homolog B (C. elegans)
chr11_-_35441099 10.638 NM_004171
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chrX_+_64708614 10.607 NM_001010888
ZC3H12B
zinc finger CCCH-type containing 12B
chr6_+_43543877 10.518 NM_006502
POLH
polymerase (DNA directed), eta
chr14_+_69658193 10.516 NM_001193360
NM_001193361
NM_018199
EXD2


exonuclease 3'-5' domain containing 2


chr21_-_34100316 10.461 NM_003895
NM_203446
SYNJ1

synaptojanin 1

chr3_-_66550844 10.360 NM_015541
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr2_-_51259536 10.337 NM_001135659
NM_004801
NRXN1

neurexin 1

chr14_+_69658482 10.281 NM_001193362
NM_001193363
EXD2

exonuclease 3'-5' domain containing 2

chr3_-_171177851 10.169 NM_001161560
NM_001161561
NM_001161562
NM_001161563
NM_001161564
NM_001161565
NM_001161566
NM_015028
TNIK







TRAF2 and NCK interacting kinase







chr8_-_53322200 10.150 NM_014682
ST18
suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)
chr3_-_14583587 10.126 NM_001080423
GRIP2
glutamate receptor interacting protein 2
chr8_-_82024277 10.011 NM_018440
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr6_+_73076431 9.960 NM_001168411
RIMS1
regulating synaptic membrane exocytosis 1
chr21_+_27107257 9.919 NM_001197297
GABPA
GA binding protein transcription factor, alpha subunit 60kDa
chr20_-_41818464 9.901 NM_007050
NM_133170
PTPRT

protein tyrosine phosphatase, receptor type, T

chr11_+_63606346 9.898 NM_001039469
NM_001163296
NM_001163297
NM_004954
MARK2



MAP/microtubule affinity-regulating kinase 2



chr15_+_63569748 9.891 NM_001145646
NM_031301
APH1B

anterior pharynx defective 1 homolog B (C. elegans)

chr6_-_80656870 9.890 NM_022726
ELOVL4
ELOVL fatty acid elongase 4
chr7_-_44924946 9.845 NM_033224
PURB
purine-rich element binding protein B
chr11_-_75236418 9.810 NM_030792
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr18_-_25757351 9.615 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr2_-_208489972 9.614 NM_001127395
METTL21A
methyltransferase like 21A
chr21_-_34100228 9.578 NM_001160302
NM_001160306
SYNJ1

synaptojanin 1

chr7_+_106685007 9.551 NM_002736
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr10_-_118765087 9.517 NM_001127211
NM_018330
KIAA1598

KIAA1598

chr11_+_121322848 9.469 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr5_+_61601944 9.450 NM_001098511
NM_001243952
NM_001243953
NM_004520
KIF2A



kinesin heavy chain member 2A



chr5_+_139493689 9.364 NM_005859
PURA
purine-rich element binding protein A
chr11_+_73882316 9.277 NM_016147
PPME1
protein phosphatase methylesterase 1
chr5_-_132299263 9.271 NM_014423
AFF4
AF4/FMR2 family, member 4
chr12_-_112819755 9.177 NM_001109662
C12orf51
chromosome 12 open reading frame 51
chrX_+_133507299 9.172 NM_001015877
NM_032335
NM_032458
PHF6


PHD finger protein 6


chr2_-_44588943 9.148 NM_001171603
NM_001171617
PREPL

prolyl endopeptidase-like

chr11_-_78052925 9.122 NM_012296
GAB2
GRB2-associated binding protein 2
chr2_+_105858199 9.119 NM_007227
GPR45
G protein-coupled receptor 45
chr3_+_124303505 9.003 NM_007064
KALRN
kalirin, RhoGEF kinase

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.54 8.28e-15 GO:0007399 nervous system development
1.67 4.08e-09 GO:0023052 signaling
3.44 1.67e-08 GO:0007268 synaptic transmission
3.21 4.38e-08 GO:0019226 transmission of nerve impulse
3.21 4.38e-08 GO:0035637 multicellular organismal signaling
2.52 1.98e-07 GO:0048699 generation of neurons
2.46 2.39e-07 GO:0022008 neurogenesis
2.91 3.88e-07 GO:0048666 neuron development
2.60 4.96e-07 GO:0007267 cell-cell signaling
2.67 6.28e-07 GO:0030182 neuron differentiation
2.40 9.22e-07 GO:0048468 cell development
1.36 9.86e-07 GO:0050794 regulation of cellular process
1.32 1.05e-06 GO:0065007 biological regulation
2.98 1.99e-06 GO:0031175 neuron projection development
1.34 2.37e-06 GO:0050789 regulation of biological process
1.62 5.32e-06 GO:0048856 anatomical structure development
1.53 1.58e-05 GO:0032502 developmental process
2.95 1.84e-05 GO:0048812 neuron projection morphogenesis
1.56 2.13e-05 GO:0007275 multicellular organismal development
2.56 2.88e-05 GO:0030030 cell projection organization
1.40 5.60e-05 GO:0032501 multicellular organismal process
1.62 5.85e-05 GO:0048731 system development
2.72 6.46e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
2.15 7.18e-05 GO:0007154 cell communication
1.18 1.08e-04 GO:0009987 cellular process
2.71 1.08e-04 GO:0048858 cell projection morphogenesis
2.84 1.30e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
2.68 1.34e-04 GO:0032990 cell part morphogenesis
2.85 1.83e-04 GO:0007409 axonogenesis
1.72 2.09e-04 GO:0030154 cell differentiation
2.39 3.79e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.51 4.26e-04 GO:0007165 signal transduction
1.49 6.84e-04 GO:0051179 localization
1.68 7.20e-04 GO:0048869 cellular developmental process
2.57 8.17e-04 GO:0000904 cell morphogenesis involved in differentiation
1.86 1.27e-03 GO:0035556 intracellular signal transduction
2.35 2.24e-03 GO:0000902 cell morphogenesis
2.79 6.36e-03 GO:0007411 axon guidance
2.23 7.55e-03 GO:0032989 cellular component morphogenesis
2.38 9.19e-03 GO:0007417 central nervous system development
1.92 9.91e-03 GO:0006793 phosphorus metabolic process
1.92 9.91e-03 GO:0006796 phosphate metabolic process
1.64 1.12e-02 GO:0006464 protein modification process
1.62 1.30e-02 GO:0043412 macromolecule modification
2.60 1.49e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.47 1.81e-02 GO:0006810 transport
1.46 2.18e-02 GO:0051234 establishment of localization
4.13 2.39e-02 GO:0019933 cAMP-mediated signaling
1.36 3.29e-02 GO:0051716 cellular response to stimulus
1.64 3.98e-02 GO:0023051 regulation of signaling
7.49 4.61e-02 GO:0071377 cellular response to glucagon stimulus
1.41 4.66e-02 GO:0016043 cellular component organization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
3.45 5.28e-09 GO:0045202 synapse
1.32 2.90e-07 GO:0016020 membrane
1.52 2.98e-07 GO:0005886 plasma membrane
3.57 5.12e-07 GO:0044456 synapse part
1.50 9.27e-07 GO:0071944 cell periphery
1.73 4.26e-06 GO:0044459 plasma membrane part
2.42 7.70e-05 GO:0030054 cell junction
2.29 7.96e-04 GO:0044431 Golgi apparatus part
2.42 1.25e-03 GO:0000139 Golgi membrane
1.93 1.37e-03 GO:0005794 Golgi apparatus
4.50 1.70e-03 GO:0019717 synaptosome
1.26 5.55e-03 GO:0044425 membrane part
2.42 6.94e-03 GO:0043005 neuron projection
1.07 7.55e-03 GO:0044464 cell part
1.07 7.67e-03 GO:0005623 cell
3.55 1.17e-02 GO:0034703 cation channel complex
1.72 1.18e-02 GO:0005887 integral to plasma membrane
1.69 1.99e-02 GO:0031226 intrinsic to plasma membrane
6.48 2.32e-02 GO:0042734 presynaptic membrane
2.80 3.83e-02 GO:0034702 ion channel complex
1.57 4.68e-02 GO:0005856 cytoskeleton

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.01 4.22e-04 GO:0005083 small GTPase regulator activity
2.47 1.06e-03 GO:0030695 GTPase regulator activity
2.85 1.13e-03 GO:0022836 gated channel activity
2.41 1.86e-03 GO:0060589 nucleoside-triphosphatase regulator activity
2.49 2.65e-03 GO:0015267 channel activity
2.49 2.78e-03 GO:0022803 passive transmembrane transporter activity
2.52 3.10e-03 GO:0005216 ion channel activity
2.48 4.15e-03 GO:0022838 substrate-specific channel activity
2.73 1.32e-02 GO:0005261 cation channel activity
3.38 2.76e-02 GO:0022843 voltage-gated cation channel activity
1.89 4.28e-02 GO:0015075 ion transmembrane transporter activity
2.93 4.76e-02 GO:0005244 voltage-gated ion channel activity
2.93 4.76e-02 GO:0022832 voltage-gated channel activity
9.52 4.87e-02 GO:0008601 protein phosphatase type 2A regulator activity