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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: XBP1.p3

Z-value: 4.530

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr3_+_171758289	148.665	NM_001135095	FNDC3B	fibronectin type III domain containing 3B
chr3_-_57583080	129.257		ARF4	ADP-ribosylation factor 4
chr7_-_6523689	108.154	NM_001100603 NM_006854	KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr3_-_57582866	103.965		ARF4	ADP-ribosylation factor 4
chr3_-_57583090	101.055		ARF4	ADP-ribosylation factor 4
chr2_-_69614321	99.375	NM_001244710 NM_002056	GFPT1	glutamine--fructose-6-phosphate transaminase 1
chr6_-_7910716	96.791	NM_030810	TXNDC5	thioredoxin domain containing 5 (endoplasmic reticulum)
chr1_-_43736600	95.112		EBNA1BP2	EBNA1 binding protein 2
chr6_-_7910278	94.470	NM_001145549	TXNDC5	thioredoxin domain containing 5 (endoplasmic reticulum)
chr3_-_57583153	90.534	NM_001660	ARF4	ADP-ribosylation factor 4
chr7_+_128379345	88.452	NM_001130674 NM_001199671 NM_001199672 NM_001199673 NM_001199674 NM_001219	CALU	calumenin
chr15_+_79603427	87.183	NM_007364	TMED3	transmembrane emp24 protein transport domain containing 3
chr15_+_79603497	86.420		TMED3	transmembrane emp24 protein transport domain containing 3
chr3_+_133524671	80.540		SRPRB	signal recognition particle receptor, B subunit
chr15_-_60690115	79.251	NM_001002857 NM_001002858 NM_001136015 NM_004039	ANXA2	annexin A2
chr3_+_133524636	76.326		SRPRB	signal recognition particle receptor, B subunit
chr12_-_106641675	74.922	NM_006825	CKAP4	cytoskeleton-associated protein 4
chr3_+_127771287	73.237		SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)
chr7_+_128379400	69.663		CALU	calumenin
chr7_-_54826864	68.085		SEC61G	Sec61 gamma subunit
chr7_+_128379428	67.323		CALU	calumenin
chr7_+_128379452	67.220		CALU	calumenin
chr7_+_128379395	66.641		CALU	calumenin
chr1_-_24126031	66.119	NM_001127621	GALE	UDP-galactose-4-epimerase
chr2_+_171785624	60.017		GORASP2	golgi reassembly stacking protein 2, 55kDa
chr5_-_10761344	57.758	NM_004394	DAP	death-associated protein
chr11_-_66056607	56.783	NM_020470	YIF1A	Yip1 interacting factor homolog A (S. cerevisiae)
chr5_-_131563481	55.116	NM_001017974 NM_001142598 NM_001142599	P4HA2	prolyl 4-hydroxylase, alpha polypeptide II
chr2_+_171785780	54.987		GORASP2	golgi reassembly stacking protein 2, 55kDa
chr3_+_100428393	54.896		TFG	TRK-fused gene
chr5_-_10761341	54.534		DAP	death-associated protein
chr7_+_94023872	54.170	NM_000089	COL1A2	collagen, type I, alpha 2
chr11_+_17298278	53.836	NM_005013	NUCB2	nucleobindin 2
chr11_-_66056455	51.684		YIF1A	Yip1 interacting factor homolog A (S. cerevisiae)
chr3_-_128369525	51.045		RPN1	ribophorin I
chr5_-_10761179	50.924		DAP	death-associated protein
chr2_-_20251788	50.507	NM_014713	LAPTM4A	lysosomal protein transmembrane 4 alpha
chr12_+_124069053	50.468	NM_006815	TMED2	transmembrane emp24 domain trafficking protein 2
chr5_-_121414011	49.159	NM_002317	LOX	lysyl oxidase
chr5_+_115177616	48.136	NM_001284	AP3S1	adaptor-related protein complex 3, sigma 1 subunit
chr2_-_33824294	48.100	NM_015475	FAM98A	family with sequence similarity 98, member A
chr11_+_61560352	47.833		FEN1	flap structure-specific endonuclease 1
chr14_-_24664758	47.398	NM_001014842 NM_006405	TM9SF1	transmembrane 9 superfamily member 1
chr14_-_24664606	47.046		TM9SF1	transmembrane 9 superfamily member 1
chr6_-_108279307	45.959		SEC63	SEC63 homolog (S. cerevisiae)
chr6_-_108279320	45.513		SEC63	SEC63 homolog (S. cerevisiae)
chr3_+_100428133	44.716	NM_001007565 NM_001195479 NM_006070	TFG	TRK-fused gene
chr16_-_75529278	44.353
chr10_+_89419352	43.972	NM_001015880 NM_004670	PAPSS2	3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr11_+_61560108	43.808	NM_004111	FEN1	flap structure-specific endonuclease 1
chr14_-_39572414	43.324	NM_006364	SEC23A	Sec23 homolog A (S. cerevisiae)
chr12_+_124069099	42.806		TMED2	transmembrane emp24 domain trafficking protein 2
chr11_+_32112414	42.097	NM_002901	RCN1	reticulocalbin 1, EF-hand calcium binding domain
chr5_-_137088952	41.537		HNRNPA0	heterogeneous nuclear ribonucleoprotein A0
chr9_+_100818941	41.425	NM_018946	NANS	N-acetylneuraminic acid synthase
chr2_-_242212244	41.203	NM_001243900 NM_203346	HDLBP	high density lipoprotein binding protein
chr1_+_161123755	41.143		UFC1	ubiquitin-fold modifier conjugating enzyme 1
chr21_-_18985104	40.952		BTG3	BTG family, member 3
chr7_-_54826899	40.823	NM_001012456 NM_014302	SEC61G	Sec61 gamma subunit
chr11_-_118927872	40.808	NM_006389 NM_001130991	HYOU1	hypoxia up-regulated 1
chr6_-_109703553	40.056		CD164	CD164 molecule, sialomucin
chrX_+_153060073	39.754		SSR4	signal sequence receptor, delta
chr11_+_69455938	39.225		CCND1	cyclin D1
chr11_-_61560052	38.876	NM_014206	C11orf10	chromosome 11 open reading frame 10
chr4_+_38869346	38.531	NM_138389	FAM114A1	family with sequence similarity 114, member A1
chr12_+_124069080	38.426		TMED2	transmembrane emp24 domain trafficking protein 2
chr8_-_124054491	38.368		DERL1	Der1-like domain family, member 1
chr14_+_52456322	38.270		C14orf166	chromosome 14 open reading frame 166
chr11_-_118927851	37.234		HYOU1	hypoxia up-regulated 1
chr1_-_11120001	37.109		SRM	spermidine synthase
chr17_-_40575117	36.992	NM_012232	PTRF	polymerase I and transcript release factor
chr17_+_15848230	36.751	NM_000676	ADORA2B	adenosine A2b receptor
chr20_+_44044706	36.133	NM_001184728 NM_001184729 NM_001184730 NM_015937	PIGT	phosphatidylinositol glycan anchor biosynthesis, class T
chr21_-_18985224	36.116	NM_001130914 NM_006806	BTG3	BTG family, member 3
chr14_+_52456192	35.738	NM_016039	C14orf166	chromosome 14 open reading frame 166
chr18_+_34409058	35.221	NM_020776	KIAA1328	KIAA1328
chr14_-_50087326	35.165	NM_001001	RPL36AL	ribosomal protein L36a-like
chr1_-_87379784	34.254		SEP15	15 kDa selenoprotein
chr1_-_87379808	33.901		SEP15	15 kDa selenoprotein
chr11_+_32605337	33.575		EIF3M	eukaryotic translation initiation factor 3, subunit M
chrX_+_153059903	33.249	NM_001204526 NM_006280	SSR4	signal sequence receptor, delta
chr2_+_85132762	32.984	NM_021103	TMSB10	thymosin beta 10
chr10_-_120840296	32.963		EIF3A	eukaryotic translation initiation factor 3, subunit A
chr21_-_18985189	32.482		BTG3	BTG family, member 3
chr3_+_33155447	32.131	NM_006371	CRTAP	cartilage associated protein
chr3_+_100428361	32.077	NM_001195478	TFG	TRK-fused gene
chrX_+_153059629	32.058	NM_001204527	SSR4	signal sequence receptor, delta
chr1_-_11120076	31.833		SRM	spermidine synthase
chr11_+_32112607	31.697		RCN1	reticulocalbin 1, EF-hand calcium binding domain
chr6_+_33168602	31.608	NM_001077516 NM_006979	SLC39A7	solute carrier family 39 (zinc transporter), member 7
chr20_+_31407696	31.579	NM_012325	MAPRE1	microtubule-associated protein, RP/EB family, member 1
chr3_+_122785855	31.549	NM_006810	PDIA5	protein disulfide isomerase family A, member 5
chr11_-_118927815	31.413		HYOU1	hypoxia up-regulated 1
chr7_-_30066124	31.262	NM_017946	FKBP14	FK506 binding protein 14, 22 kDa
chr1_-_11120081	31.045	NM_003132	SRM	spermidine synthase
chr1_-_45988561	30.839	NM_001202431	PRDX1	peroxiredoxin 1
chr10_-_71930185	30.418	NM_001142648 NM_020150	SAR1A	SAR1 homolog A (S. cerevisiae)
chr8_-_124054540	29.533		DERL1	Der1-like domain family, member 1
chr1_-_11120047	29.478		SRM	spermidine synthase
chr13_-_31040035	29.050	NM_002128	HMGB1	high mobility group box 1
chr11_+_118443140	28.967		ARCN1	archain 1
chr1_+_228270429	28.788		ARF1	ADP-ribosylation factor 1
chr4_-_119757183	28.722		SEC24D	SEC24 family, member D (S. cerevisiae)
chr9_-_35732226	28.449		TLN1	talin 1
chr2_+_85132999	28.414		TMSB10	thymosin beta 10
chr2_+_242254722	28.109	NM_001008491 NM_006155	SEPT2	septin 2
chr11_+_61560401	28.024		FEN1	flap structure-specific endonuclease 1
chr19_-_29704021	27.619		UQCRFS1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr2_-_20251400	27.538		LAPTM4A	lysosomal protein transmembrane 4 alpha
chr1_+_110527327	27.465	NM_001242673 NM_006621	AHCYL1	adenosylhomocysteinase-like 1
chr8_-_124054591	27.228	NM_001134671 NM_024295	DERL1	Der1-like domain family, member 1
chrX_+_67718868	26.888		YIPF6	Yip1 domain family, member 6
chr10_-_98346594	26.812		TM9SF3	transmembrane 9 superfamily member 3
chr9_+_114393543	26.513	NM_001015882 NM_004125	DNAJC25 DNAJC25-GNG10	DnaJ (Hsp40) homolog, subfamily C , member 25 DNAJC25-GNG10 readthrough
chr11_-_62414086	26.485		GANAB	glucosidase, alpha; neutral AB
chr18_-_47018842	26.353	NM_001199356 NM_000985 NM_001035006 NM_001199340 NM_001199345	RPL17-C18ORF32 RPL17	RPL17-C18orf32 readthrough ribosomal protein L17
chr2_-_242254984	26.215		HDLBP	high density lipoprotein binding protein
chr6_-_90062349	26.141		UBE2J1	ubiquitin-conjugating enzyme E2, J1, U
chr6_+_30294224	26.040
chr18_-_47018777	25.954		RPL17	ribosomal protein L17
chr6_+_116692098	25.824	NM_013352	DSE	dermatan sulfate epimerase
chr18_-_47018822	25.752	NM_001199341 NM_001199342 NM_001199343 NM_001199344	RPL17	ribosomal protein L17
chr1_+_87170486	25.604		SH3GLB1	SH3-domain GRB2-like endophilin B1
chr17_+_15848422	25.558		ADORA2B	adenosine A2b receptor
chr21_+_42539727	25.497	NM_012105 NM_138991 NM_138992	BACE2	beta-site APP-cleaving enzyme 2
chr13_-_31039966	25.044		HMGB1	high mobility group box 1
chr11_-_118972529	24.975		DPAGT1	dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr11_+_118443091	24.768	NM_001142281 NM_001655	ARCN1	archain 1
chr4_-_119757288	24.651	NM_014822	SEC24D	SEC24 family, member D (S. cerevisiae)
chr19_-_29704107	24.352	NM_006003	UQCRFS1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr15_+_44038483	24.217	NM_005313	PDIA3	protein disulfide isomerase family A, member 3
chr11_-_62414063	24.001		GANAB	glucosidase, alpha; neutral AB
chr15_+_44038649	23.607		PDIA3	protein disulfide isomerase family A, member 3
chr11_-_62414096	23.456	NM_198334 NM_198335	GANAB	glucosidase, alpha; neutral AB
chr17_+_37026309	23.408		LASP1	LIM and SH3 protein 1
chrX_+_77359665	23.127	NM_000291	PGK1	phosphoglycerate kinase 1
chr2_-_20251280	23.010		LAPTM4A	lysosomal protein transmembrane 4 alpha
chr2_+_216176808	22.803		ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr10_-_98346793	22.797	NM_020123	TM9SF3	transmembrane 9 superfamily member 3
chr1_-_87380008	22.706	NM_004261 NM_203341	SEP15	15 kDa selenoprotein
chr5_-_121413906	22.411		LOX	lysyl oxidase
chrX_+_77359768	22.012		PGK1	phosphoglycerate kinase 1
chrX_+_77359754	21.931		PGK1	phosphoglycerate kinase 1
chr12_+_58120029	21.656		LOC100130776	uncharacterized LOC100130776
chr22_-_43253186	21.632		ARFGAP3	ADP-ribosylation factor GTPase activating protein 3
chr12_-_101801499	21.528	NM_001177	ARL1	ADP-ribosylation factor-like 1
chr1_+_110527432	21.338		AHCYL1	adenosylhomocysteinase-like 1
chr2_-_99952779	20.887	NM_005783	TXNDC9	thioredoxin domain containing 9
chr3_-_49395751	20.532	NM_000581 NM_201397	GPX1	glutathione peroxidase 1
chr9_-_35732175	20.422		TLN1	talin 1
chr15_-_90645621	19.989		IDH2	isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr17_+_37026351	19.519		LASP1	LIM and SH3 protein 1
chr9_+_91926109	19.502	NM_001827	CKS2	CDC28 protein kinase regulatory subunit 2
chrX_+_77359712	19.405		PGK1	phosphoglycerate kinase 1
chr12_-_109125289	19.393	NM_014325	CORO1C	coronin, actin binding protein, 1C
chr9_-_35072545	19.367		VCP	valosin containing protein
chr9_+_35732629	19.281		CREB3	cAMP responsive element binding protein 3
chr7_+_94024201	19.084		COL1A2	collagen, type I, alpha 2
chr6_-_90062439	19.034		UBE2J1	ubiquitin-conjugating enzyme E2, J1, U
chr2_+_198365113	18.969		HSPE1	heat shock 10kDa protein 1 (chaperonin 10)
chr19_-_2038937	18.852		MKNK2	MAP kinase interacting serine/threonine kinase 2
chr8_-_81083660	18.522	NM_001025253 NM_005079	TPD52	tumor protein D52
chr11_+_125462751	18.503		STT3A	STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
chr9_+_35732498	18.421		CREB3	cAMP responsive element binding protein 3
chr4_-_47916498	18.205	NM_152995	NFXL1	nuclear transcription factor, X-box binding-like 1
chr15_+_44038659	18.026		PDIA3	protein disulfide isomerase family A, member 3
chrX_+_47050208	18.000		UBA1	ubiquitin-like modifier activating enzyme 1
chr1_+_110527307	17.468		AHCYL1	adenosylhomocysteinase-like 1
chr12_+_54718927	17.233		COPZ1	coatomer protein complex, subunit zeta 1
chr6_-_109702902	17.217		CD164	CD164 molecule, sialomucin
chr9_-_35732115	17.132		TLN1	talin 1
chr1_+_87170515	17.097		SH3GLB1	SH3-domain GRB2-like endophilin B1
chr22_-_43253304	17.038	NM_001142293 NM_014570	ARFGAP3	ADP-ribosylation factor GTPase activating protein 3
chr6_+_34204663	17.004		HMGA1	high mobility group AT-hook 1
chr3_-_10362724	16.951	NM_001136232	SEC13	SEC13 homolog (S. cerevisiae)
chr2_+_200819928	16.757	NM_024520	C2orf47	chromosome 2 open reading frame 47
chr12_+_54718910	16.433	NM_016057	COPZ1	coatomer protein complex, subunit zeta 1
chr12_-_92539614	16.350	NM_001731	BTG1	B-cell translocation gene 1, anti-proliferative
chr12_+_54718925	16.279		COPZ1	coatomer protein complex, subunit zeta 1
chr2_+_27255745	16.244	NM_001083590 NM_017727	TMEM214	transmembrane protein 214
chr2_+_27255837	16.230		TMEM214	transmembrane protein 214
chr6_+_7107986	16.132	NM_001003698 NM_001003699 NM_001003700	RREB1	ras responsive element binding protein 1
chr12_-_82752154	15.727	NM_014167	CCDC59	coiled-coil domain containing 59
chr2_-_242212198	15.705		HDLBP	high density lipoprotein binding protein
chr5_+_34656367	15.524	NM_001145522 NM_015577	RAI14	retinoic acid induced 14
chr7_-_128045995	15.345	NM_001142573 NM_001142574 NM_001142575	IMPDH1	IMP (inosine 5'-monophosphate) dehydrogenase 1
chr14_-_39572278	15.250		SEC23A	Sec23 homolog A (S. cerevisiae)
chr11_+_65819803	15.229	NM_006842	SF3B2	splicing factor 3b, subunit 2, 145kDa
chr10_-_16859336	15.040		RSU1	Ras suppressor protein 1
chr9_+_35732207	15.016	NM_006368	CREB3	cAMP responsive element binding protein 3
chr16_-_22385596	14.980	NM_001802	CDR2	cerebellar degeneration-related protein 2, 62kDa
chr6_+_34204690	14.745		HMGA1	high mobility group AT-hook 1
chr20_-_17662828	14.633	NM_001042576 NM_004587	RRBP1	ribosome binding protein 1 homolog 180kDa (dog)
chr15_-_90645709	14.586		IDH2	isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr12_+_57623827	14.394	NM_001166358 NM_001166359 NM_001166357	SHMT2	serine hydroxymethyltransferase 2 (mitochondrial)
chr5_+_149340287	14.379	NM_000112	SLC26A2	solute carrier family 26 (sulfate transporter), member 2
chr5_-_9546157	14.368	NM_003966	SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr16_+_66586479	14.057		CKLF	chemokine-like factor
chr19_+_54618789	14.028	NM_015629	PRPF31	PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
chr3_+_127771126	13.921	NM_013336	SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
11.07	6.32e-12	GO:0006487	protein N-linked glycosylation
3.48	1.19e-11	GO:0015031	protein transport
3.41	2.40e-11	GO:0045184	establishment of protein localization
11.22	2.60e-11	GO:0018196	peptidyl-asparagine modification
11.22	2.60e-11	GO:0018279	protein N-linked glycosylation via asparagine
8.53	5.57e-11	GO:0048193	Golgi vesicle transport
3.47	1.74e-10	GO:0046907	intracellular transport
4.74	3.26e-10	GO:0006886	intracellular protein transport
3.00	3.59e-10	GO:0008104	protein localization
2.95	4.37e-10	GO:0051649	establishment of localization in cell
2.78	6.98e-10	GO:0051641	cellular localization
26.81	8.05e-10	GO:0048199	vesicle targeting, to, from or within Golgi
2.13	1.46e-09	GO:0044267	cellular protein metabolic process
1.57	1.65e-09	GO:0044237	cellular metabolic process
1.29	2.07e-09	GO:0009987	cellular process
4.00	3.31e-09	GO:0034613	cellular protein localization
3.98	3.97e-09	GO:0070727	cellular macromolecule localization
6.79	5.54e-09	GO:0043687	post-translational protein modification
22.34	8.00e-09	GO:0006901	vesicle coating
4.20	8.74e-09	GO:0044262	cellular carbohydrate metabolic process
2.63	1.05e-08	GO:0033036	macromolecule localization
3.30	1.06e-08	GO:0016192	vesicle-mediated transport
21.45	1.31e-08	GO:0006900	membrane budding
6.66	2.54e-08	GO:0006486	protein glycosylation
6.66	2.54e-08	GO:0043413	macromolecule glycosylation
6.62	2.85e-08	GO:0070085	glycosylation
1.47	6.50e-08	GO:0008152	metabolic process
5.87	9.15e-08	GO:0009101	glycoprotein biosynthetic process
17.87	1.11e-07	GO:0006903	vesicle targeting
1.88	3.21e-07	GO:0019538	protein metabolic process
1.49	8.53e-07	GO:0044238	primary metabolic process
1.65	9.77e-07	GO:0044260	cellular macromolecule metabolic process
3.23	2.17e-06	GO:0005975	carbohydrate metabolic process
4.17	2.23e-06	GO:0018193	peptidyl-amino acid modification
9.90	2.78e-06	GO:0016050	vesicle organization
5.34	3.72e-06	GO:0006457	protein folding
4.79	3.83e-06	GO:0009100	glycoprotein metabolic process
12.77	4.46e-06	GO:0051650	establishment of vesicle localization
1.81	5.52e-06	GO:0051234	establishment of localization
1.81	5.76e-06	GO:0006810	transport
1.72	7.89e-06	GO:0051179	localization
22.08	1.41e-05	GO:0070972	protein localization in endoplasmic reticulum
1.53	3.59e-05	GO:0043170	macromolecule metabolic process
8.94	4.00e-05	GO:0045454	cell redox homeostasis
10.12	4.92e-05	GO:0051648	vesicle localization
1.82	2.57e-04	GO:0044249	cellular biosynthetic process
29.79	3.01e-04	GO:0048194	Golgi vesicle budding
29.79	3.01e-04	GO:0048200	Golgi transport vesicle coating
29.79	3.01e-04	GO:0048205	COPI coating of Golgi vesicle
29.79	3.01e-04	GO:0048207	vesicle targeting, rough ER to cis-Golgi
29.79	3.01e-04	GO:0048208	COPII vesicle coating
29.79	3.01e-04	GO:0090114	COPII-coated vesicle budding
1.79	3.22e-04	GO:0009058	biosynthetic process
1.95	3.59e-04	GO:0006464	protein modification process
7.19	4.00e-04	GO:0051656	establishment of organelle localization
1.99	5.49e-04	GO:0009059	macromolecule biosynthetic process
1.98	8.58e-04	GO:0034645	cellular macromolecule biosynthetic process
1.89	9.60e-04	GO:0043412	macromolecule modification
24.37	1.07e-03	GO:0006613	cotranslational protein targeting to membrane
5.70	1.54e-03	GO:0051640	organelle localization
15.32	2.00e-03	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
3.01	3.37e-03	GO:0016044	cellular membrane organization
3.00	3.65e-03	GO:0061024	membrane organization
9.63	7.86e-03	GO:0006888	ER to Golgi vesicle-mediated transport
26.81	9.08e-03	GO:0045047	protein targeting to ER
26.81	9.08e-03	GO:0072599	establishment of protein localization in endoplasmic reticulum
10.73	1.90e-02	GO:0006984	ER-nucleus signaling pathway
14.11	2.38e-02	GO:0030968	endoplasmic reticulum unfolded protein response
14.11	2.38e-02	GO:0034620	cellular response to unfolded protein
6.70	2.78e-02	GO:0006986	response to unfolded protein
9.75	3.37e-02	GO:0034976	response to endoplasmic reticulum stress
4.44	4.64e-02	GO:0060627	regulation of vesicle-mediated transport

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.95	3.38e-28	GO:0044444	cytoplasmic part
1.64	6.28e-25	GO:0005737	cytoplasm
3.95	4.03e-23	GO:0005783	endoplasmic reticulum
4.36	2.39e-19	GO:0044432	endoplasmic reticulum part
1.81	3.90e-18	GO:0044422	organelle part
1.36	4.97e-18	GO:0044424	intracellular part
1.82	6.13e-18	GO:0044446	intracellular organelle part
2.62	3.02e-17	GO:0031090	organelle membrane
1.32	8.54e-16	GO:0005622	intracellular
2.80	9.14e-15	GO:0012505	endomembrane system
1.39	4.30e-13	GO:0043229	intracellular organelle
1.45	4.53e-13	GO:0043231	intracellular membrane-bounded organelle
1.44	5.27e-13	GO:0043227	membrane-bounded organelle
1.39	5.60e-13	GO:0043226	organelle
3.72	5.41e-12	GO:0042175	nuclear membrane-endoplasmic reticulum network
3.72	1.05e-11	GO:0005789	endoplasmic reticulum membrane
2.84	7.62e-09	GO:0005794	Golgi apparatus
8.67	9.69e-09	GO:0005788	endoplasmic reticulum lumen
3.43	1.97e-06	GO:0000139	Golgi membrane
10.12	9.97e-06	GO:0005793	ER-Golgi intermediate compartment
2.75	1.54e-05	GO:0016023	cytoplasmic membrane-bounded vesicle
2.66	2.23e-05	GO:0031410	cytoplasmic vesicle
2.70	2.43e-05	GO:0031988	membrane-bounded vesicle
22.98	2.50e-05	GO:0030663	COPI coated vesicle membrane
2.91	4.28e-05	GO:0044431	Golgi apparatus part
2.57	4.95e-05	GO:0031982	vesicle
8.13	8.70e-05	GO:0030117	membrane coat
8.13	8.70e-05	GO:0048475	coated membrane
18.92	9.81e-05	GO:0030137	COPI-coated vesicle
11.00	1.17e-04	GO:0030120	vesicle coat
1.81	3.15e-04	GO:0005829	cytosol
1.09	1.28e-03	GO:0044464	cell part
1.09	1.30e-03	GO:0005623	cell
17.87	1.32e-03	GO:0030867	rough endoplasmic reticulum membrane
7.80	1.79e-03	GO:0030176	integral to endoplasmic reticulum membrane
26.81	1.84e-03	GO:0030127	COPII vesicle coat
16.76	1.89e-03	GO:0012507	ER to Golgi transport vesicle membrane
1.71	2.06e-03	GO:0070013	intracellular organelle lumen
5.13	2.38e-03	GO:0030662	coated vesicle membrane
1.67	3.94e-03	GO:0043233	organelle lumen
2.63	3.95e-03	GO:0030529	ribonucleoprotein complex
1.51	3.96e-03	GO:0032991	macromolecular complex
14.11	4.81e-03	GO:0030134	ER to Golgi transport vesicle
10.05	5.67e-03	GO:0030660	Golgi-associated vesicle membrane
1.64	6.64e-03	GO:0031974	membrane-enclosed lumen
3.33	6.80e-03	GO:0030659	cytoplasmic vesicle membrane
5.42	9.84e-03	GO:0042470	melanosome
5.42	9.84e-03	GO:0048770	pigment granule
3.22	1.03e-02	GO:0012506	vesicle membrane
17.87	1.23e-02	GO:0030126	COPI vesicle coat
5.96	1.34e-02	GO:0031227	intrinsic to endoplasmic reticulum membrane
6.95	1.44e-02	GO:0005798	Golgi-associated vesicle
32.17	1.47e-02	GO:0005797	Golgi medial cisterna
8.47	1.57e-02	GO:0005791	rough endoplasmic reticulum
3.54	2.04e-02	GO:0030135	coated vesicle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
5.87	3.31e-05	GO:0016853	isomerase activity
1.36	5.10e-05	GO:0005515	protein binding
13.41	1.72e-04	GO:0015035	protein disulfide oxidoreductase activity
12.11	3.64e-04	GO:0015036	disulfide oxidoreductase activity
6.31	1.11e-03	GO:0008565	protein transporter activity
8.41	1.18e-03	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors
2.41	2.41e-03	GO:0016491	oxidoreductase activity
23.83	3.85e-03	GO:0003756	protein disulfide isomerase activity
23.83	3.85e-03	GO:0016862	intramolecular oxidoreductase activity, interconverting keto- and enol-groups
23.83	3.85e-03	GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds
1.35	1.24e-02	GO:0003824	catalytic activity