Motif ID: ZEB1.p2

Z-value: 1.709


Transcription factors associated with ZEB1.p2:

Gene SymbolEntrez IDGene Name
ZEB1 6935 zinc finger E-box binding homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZEB1chr10_+_31607419-0.433.8e-11Click!


Activity profile for motif ZEB1.p2.

activity profile for motif ZEB1.p2


Sorted Z-values histogram for motif ZEB1.p2

Sorted Z-values for motif ZEB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZEB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_38755097 49.281 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr19_+_38755238 48.152 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_38755422 46.062 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_35739778 23.743 LSR
lipolysis stimulated lipoprotein receptor
chr19_+_35739519 23.185 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor


chr2_+_47596447 22.760 EPCAM
epithelial cell adhesion molecule
chr2_+_47596286 22.377 NM_002354
EPCAM
epithelial cell adhesion molecule
chr9_-_97401588 22.236 FBP1
fructose-1,6-bisphosphatase 1
chr17_-_39942937 18.999 NM_002230
NM_021991
JUP

junction plakoglobin

chr9_-_97401746 18.653 FBP1
fructose-1,6-bisphosphatase 1
chr17_-_39684499 18.623 KRT19
keratin 19
chr6_+_7541837 18.119 DSP
desmoplakin
chr17_-_7165788 17.957 CLDN7
claudin 7
chr6_+_7541892 16.811 DSP
desmoplakin
chr19_+_35739282 16.771 LSR
lipolysis stimulated lipoprotein receptor
chr19_+_35739838 16.713 LSR
lipolysis stimulated lipoprotein receptor
chr16_+_68771192 16.501 NM_004360
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr6_+_7541863 15.522 NM_001008844
NM_004415
DSP

desmoplakin

chr9_-_97401833 14.479 NM_000507
FBP1
fructose-1,6-bisphosphatase 1
chr17_-_7166263 14.270 NM_001185023
NM_001307
CLDN7

claudin 7

chr16_+_68771214 13.380 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr11_-_63933493 12.652 NM_014067
MACROD1
MACRO domain containing 1
chr4_+_75310852 11.694 NM_001657
AREG
amphiregulin
chr14_-_61747956 11.560 TMEM30B
transmembrane protein 30B
chr7_-_73184535 10.968 NM_001306
CLDN3
claudin 3
chr4_+_75480628 10.834 NM_001657
AREG
amphiregulin
chr1_+_1981902 10.790 NM_002744
PRKCZ
protein kinase C, zeta
chr8_+_95653272 10.614 ESRP1
epithelial splicing regulatory protein 1
chr11_-_63933204 10.267 MACROD1
MACRO domain containing 1
chr17_-_31203889 10.098 NM_015194
MYO1D
myosin ID
chr14_-_67878859 8.172 PLEK2
pleckstrin 2
chr19_+_7702010 8.148 STXBP2
syntaxin binding protein 2
chr14_-_67878770 8.107 NM_016445
PLEK2
pleckstrin 2
chr17_+_7211260 7.984 NM_001143761
EIF5A
eukaryotic translation initiation factor 5A
chr19_+_7701976 7.752 NM_001127396
NM_006949
STXBP2

syntaxin binding protein 2

chr11_-_66139064 7.659 NM_001532
SLC29A2
solute carrier family 29 (nucleoside transporters), member 2
chr18_-_71959109 7.569 NM_001190807
NM_001914
NM_148923
CYB5A


cytochrome b5 type A (microsomal)


chr12_+_56473808 7.236 NM_001982
NM_001005915
ERBB3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

chr12_+_56473944 7.133 ERBB3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
chr14_-_61748510 7.078 NM_001017970
TMEM30B
transmembrane protein 30B
chr3_+_47021146 6.999 NM_015175
NBEAL2
neurobeachin-like 2
chr17_+_73521744 6.976 NM_001015002
NM_001031803
NM_004524
LLGL2


lethal giant larvae homolog 2 (Drosophila)


chr15_-_52587851 6.958 NM_018728
MYO5C
myosin VC
chr2_+_163200582 6.866 NM_012198
GCA
grancalcin, EF-hand calcium binding protein
chr20_-_6103562 6.820 FERMT1
fermitin family member 1
chr20_-_60942300 6.750 NM_005560
LAMA5
laminin, alpha 5
chr9_+_133320093 6.568 NM_000050
NM_054012
ASS1

argininosuccinate synthase 1

chr6_+_36098261 6.531 NM_002754
MAPK13
mitogen-activated protein kinase 13
chrX_+_13671224 6.493 NM_152634
TCEANC
transcription elongation factor A (SII) N-terminal and central domain containing
chr2_+_163200623 6.436 GCA
grancalcin, EF-hand calcium binding protein
chr19_+_7702020 6.419 STXBP2
syntaxin binding protein 2
chr1_-_160990862 6.405 F11R
F11 receptor
chr6_+_111303240 6.362 NM_032194
RPF2
ribosome production factor 2 homolog (S. cerevisiae)
chr11_+_69924407 6.330 NM_018043
ANO1
anoctamin 1, calcium activated chloride channel
chr18_+_29078026 6.305 NM_001943
DSG2
desmoglein 2
chr15_+_50474357 6.244 NM_001159629
NM_003645
SLC27A2

solute carrier family 27 (fatty acid transporter), member 2

chr11_-_1330891 6.209 NM_019009
TOLLIP
toll interacting protein
chr17_+_7210841 6.148 NM_001970
EIF5A
eukaryotic translation initiation factor 5A
chr7_-_994259 5.949 NM_006869
ADAP1
ArfGAP with dual PH domains 1
chr11_+_65779461 5.697 NM_001323
CST6
cystatin E/M
chr2_+_17721806 5.663 NM_003385
VSNL1
visinin-like 1
chr17_+_7210929 5.611 EIF5A
eukaryotic translation initiation factor 5A
chr1_-_27816542 5.610 WASF2
WAS protein family, member 2
chr1_-_209979388 5.525 NM_001206696
NM_006147
IRF6

interferon regulatory factor 6

chr11_+_722282 5.499 EPS8L2
EPS8-like 2
chr22_+_41777932 5.434 NM_003216
TEF
thyrotrophic embryonic factor
chr11_+_121322848 5.370 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr17_-_39684585 5.175 NM_002276
KRT19
keratin 19
chr2_+_17721983 5.108 VSNL1
visinin-like 1
chr11_-_1330808 5.098 TOLLIP
toll interacting protein
chr7_+_16793320 5.086 NM_014399
TSPAN13
tetraspanin 13
chr2_-_20424627 5.050 NM_002997
SDC1
syndecan 1
chr1_-_161008710 5.019 TSTD1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr11_-_1330840 4.936 TOLLIP
toll interacting protein
chr19_+_40854331 4.926 NM_001031696
NM_012268
PLD3

phospholipase D family, member 3

chr19_+_18794487 4.908 CRTC1
CREB regulated transcription coactivator 1
chr2_-_166650770 4.890 NM_004482
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr1_-_59042827 4.887 TACSTD2
tumor-associated calcium signal transducer 2
chr19_+_40854529 4.881 PLD3
phospholipase D family, member 3
chr1_-_59043165 4.874 NM_002353
TACSTD2
tumor-associated calcium signal transducer 2
chr11_-_1330883 4.827 TOLLIP
toll interacting protein
chr19_-_12886421 4.814 NM_001100176
NM_013312
HOOK2

hook homolog 2 (Drosophila)

chr19_-_12886263 4.810 HOOK2
hook homolog 2 (Drosophila)
chr16_-_68269948 4.790 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr1_-_2322990 4.734 NM_024848
MORN1
MORN repeat containing 1
chr16_+_68679229 4.724 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr17_+_73717515 4.684 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr16_+_50099907 4.667 HEATR3
HEAT repeat containing 3
chr1_-_161008733 4.640 NM_001113205
NM_001113206
NM_001113207
TSTD1


F11R
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1


F11 receptor
chr16_-_4987056 4.543 NM_002705
PPL
periplakin
chr20_+_43991739 4.519 NM_001099791
NM_033542
SYS1-DBNDD2
SYS1

SYS1-DBNDD2 readthrough
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)

chr1_-_2322996 4.483 MORN1
MORN repeat containing 1
chr17_-_19648771 4.482 NM_001135168
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr4_+_79472741 4.468 NM_005139
ANXA3
annexin A3
chr22_+_23222897 4.440 CYAT1
immunoglobulin lambda light chain-like
chr12_+_7055753 4.397 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr9_+_130911731 4.310 NM_005564
LCN2
lipocalin 2
chr8_-_145638929 4.308 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr1_+_229406835 4.186 NM_004578
RAB4A
RAB4A, member RAS oncogene family
chr3_-_45187861 4.147 CDCP1
CUB domain containing protein 1
chr19_-_6279797 4.096


chr5_+_68788387 4.083 NM_001205254
OCLN
occludin
chr12_+_6420098 4.065 NM_001144856
PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr10_-_21462987 4.065 NEBL
nebulette
chr10_-_21463019 4.052 NM_001173484
NM_213569
NEBL

nebulette

chr16_-_31085503 4.049 NM_024706
ZNF668
zinc finger protein 668
chr11_+_20385686 4.046 NM_001098523
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr21_-_43187197 4.023 NM_020639
RIPK4
receptor-interacting serine-threonine kinase 4
chr6_-_159240399 3.997 EZR
ezrin
chr5_+_76114832 3.969 NM_005242
F2RL1
coagulation factor II (thrombin) receptor-like 1
chr7_-_22396511 3.955 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr8_+_95653340 3.871 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr6_-_159240398 3.870 EZR
ezrin
chr19_+_18284578 3.852 NM_006332
IFI30
interferon, gamma-inducible protein 30
chr17_+_58227278 3.812 NM_000717
CA4
carbonic anhydrase IV
chr6_+_89855745 3.766 NM_001010853
PM20D2
peptidase M20 domain containing 2
chr4_-_25864430 3.766 NM_015187
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr11_-_1330680 3.765 TOLLIP
toll interacting protein
chr17_-_15902907 3.760 NM_001042697
NM_001042698
ZSWIM7

zinc finger, SWIM-type containing 7

chr7_-_150498362 3.717 NM_014020
TMEM176B
transmembrane protein 176B
chr22_-_29196537 3.714 NM_001079539
NM_005080
XBP1

X-box binding protein 1

chr19_-_18632857 3.712 ELL
elongation factor RNA polymerase II
chr15_+_41136622 3.696 NM_001032367
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr8_+_95653399 3.669 ESRP1
epithelial splicing regulatory protein 1
chr19_+_55591759 3.664 NM_017729
EPS8L1
EPS8-like 1
chr7_+_150020269 3.657 NM_001142928
NM_023942
LRRC61

leucine rich repeat containing 61

chr12_-_52914080 3.645 NM_000424
KRT5
keratin 5
chr3_-_45187897 3.640 NM_022842
NM_178181
CDCP1

CUB domain containing protein 1

chr8_-_110657025 3.636 NM_001099753
NM_001099754
NM_001099755
SYBU


syntabulin (syntaxin-interacting)


chr14_-_105635114 3.635 NM_002226
NM_145159
JAG2

jagged 2

chr19_+_49055421 3.613 NM_177973
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
chr1_+_24969766 3.606 SRRM1
serine/arginine repetitive matrix 1
chr7_+_45614179 3.600 ADCY1
adenylate cyclase 1 (brain)
chr9_+_140513443 3.600 NM_001145527
NM_024757
EHMT1

euchromatic histone-lysine N-methyltransferase 1

chr11_+_130029773 3.599 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr16_-_2390737 3.596 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr7_-_150038689 3.592 NM_002889
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr5_+_167718485 3.588 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chr19_-_18632886 3.575 NM_006532
ELL
elongation factor RNA polymerase II
chr6_+_31783530 3.573 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr6_-_159240367 3.548 EZR
ezrin
chr17_+_21279667 3.545 NM_021012
KCNJ12
potassium inwardly-rectifying channel, subfamily J, member 12
chr14_-_105634708 3.542 JAG2
jagged 2
chr18_+_11981552 3.538 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr11_+_32851469 3.523 NM_024081
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr17_+_58227330 3.516 CA4
carbonic anhydrase IV
chr16_+_811049 3.512 NM_013404
MSLN
mesothelin
chr6_-_159240433 3.497 NM_001111077
EZR
ezrin
chr21_+_45553485 3.459 NM_004649
NM_198155
C21orf33

chromosome 21 open reading frame 33

chr21_-_43187265 3.456 RIPK4
receptor-interacting serine-threonine kinase 4
chr5_+_76114881 3.447 F2RL1
coagulation factor II (thrombin) receptor-like 1
chr14_-_38064440 3.446 NM_004496
FOXA1
forkhead box A1
chr9_-_139940595 3.440 NM_015392
NPDC1
neural proliferation, differentiation and control, 1
chr19_+_18284619 3.428 IFI30
interferon, gamma-inducible protein 30
chr12_+_7055736 3.417 NM_080548
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr11_-_71159371 3.411 DHCR7
7-dehydrocholesterol reductase
chr19_-_5340700 3.405 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr17_+_73717556 3.404 ITGB4
integrin, beta 4
chr21_+_43933983 3.394 SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr11_+_130029663 3.370 NM_021978
ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr22_-_31686707 3.364 PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr7_-_994008 3.344 ADAP1
ArfGAP with dual PH domains 1
chr3_-_45187843 3.343 CDCP1
CUB domain containing protein 1
chr10_-_11653529 3.320 NM_014688
USP6NL
USP6 N-terminal like
chr10_+_71211215 3.309 NM_012339
TSPAN15
tetraspanin 15
chr16_+_31085722 3.294 NM_014699
ZNF646
zinc finger protein 646
chr14_-_54423448 3.290 NM_001202
NM_130850
BMP4

bone morphogenetic protein 4

chr16_+_30710461 3.287 NM_006662
SRCAP
Snf2-related CREBBP activator protein
chr2_+_46524448 3.277 NM_001430
EPAS1
endothelial PAS domain protein 1
chr11_-_33890931 3.264 LMO2
LIM domain only 2 (rhombotin-like 1)
chr16_+_31085751 3.262 ZNF646
zinc finger protein 646
chr14_-_38064176 3.257 FOXA1
forkhead box A1
chr19_-_2783225 3.257 SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr11_+_130029712 3.243 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr13_-_107187312 3.222 NM_004093
EFNB2
ephrin-B2
chr16_+_68771304 3.214 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr19_-_2783313 3.196 SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr22_-_36903033 3.196 FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr6_+_8435852 3.178 LOC100506207
uncharacterized LOC100506207
chr17_+_73717596 3.165 ITGB4
integrin, beta 4
chr20_+_44035203 3.151 NM_001048223
NM_001048224
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr11_+_130029699 3.141 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chrX_-_133119475 3.141 GPC3
glypican 3
chr12_-_121734543 3.135 NM_172226
CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr9_-_136857285 3.132 NM_001134398
NM_003371
VAV2

vav 2 guanine nucleotide exchange factor

chr6_-_32551993 3.119 HLA-DRB1
HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr1_+_46646199 3.109 TSPAN1
tetraspanin 1
chr16_+_27214806 3.095 NM_024773
JMJD5
jumonji domain containing 5
chr15_-_93198602 3.093 NM_207446
FAM174B
family with sequence similarity 174, member B
chr11_+_68079999 3.083 NM_002335
LRP5
low density lipoprotein receptor-related protein 5
chr6_+_30294224 3.080


chr17_+_73975297 3.079 NM_001113324
TEN1
TEN1-CDK3
TEN1 telomerase capping complex subunit homolog (S. cerevisiae)
TEN1-CDK3 readthrough
chr1_+_183155393 3.065 LAMC2
laminin, gamma 2
chr5_+_79783799 3.043 NM_205548
FAM151B
family with sequence similarity 151, member B
chr22_+_19701968 3.015 NM_002688
SEPT5
septin 5
chr1_-_20306908 3.009 NM_000300
NM_001161727
NM_001161728
PLA2G2A


phospholipase A2, group IIA (platelets, synovial fluid)


chr2_-_20425166 3.007 NM_001006946
SDC1
syndecan 1
chr15_+_40886442 3.004 NM_144508
NM_170589
CASC5

cancer susceptibility candidate 5

chr3_-_195717100 2.983 SDHAP1
SDHAP2
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2
chr4_-_16228071 2.978 TAPT1
transmembrane anterior posterior transformation 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.20 3.25e-18 GO:0065007 biological regulation
1.12 2.34e-15 GO:0009987 cellular process
1.20 3.57e-15 GO:0050789 regulation of biological process
1.19 4.66e-13 GO:0050794 regulation of cellular process
1.30 2.03e-12 GO:0023052 signaling
1.28 8.86e-10 GO:0007165 signal transduction
1.29 2.69e-09 GO:0048856 anatomical structure development
1.26 5.97e-09 GO:0032502 developmental process
1.27 1.02e-08 GO:0007275 multicellular organismal development
1.29 4.96e-08 GO:0048731 system development
1.30 6.49e-08 GO:0048518 positive regulation of biological process
1.37 8.19e-08 GO:0048583 regulation of response to stimulus
1.22 4.30e-07 GO:0051716 cellular response to stimulus
1.44 5.23e-07 GO:0051239 regulation of multicellular organismal process
1.36 9.97e-07 GO:0007166 cell surface receptor linked signaling pathway
1.39 4.51e-06 GO:0009966 regulation of signal transduction
1.36 5.38e-06 GO:0023051 regulation of signaling
1.17 5.95e-06 GO:0032501 multicellular organismal process
1.49 1.33e-05 GO:0006351 transcription, DNA-dependent
1.13 2.72e-05 GO:0008152 metabolic process
1.14 6.53e-05 GO:0050896 response to stimulus
1.28 7.16e-05 GO:0042221 response to chemical stimulus
1.31 7.55e-05 GO:0048513 organ development
1.14 9.45e-05 GO:0044238 primary metabolic process
1.26 9.65e-05 GO:0048522 positive regulation of cellular process
1.43 2.25e-04 GO:0032774 RNA biosynthetic process
1.18 5.36e-04 GO:0019222 regulation of metabolic process
1.13 5.41e-04 GO:0044237 cellular metabolic process
1.33 1.24e-03 GO:0035556 intracellular signal transduction
1.26 1.30e-03 GO:0065008 regulation of biological quality
1.41 1.86e-03 GO:0050793 regulation of developmental process
1.38 3.09e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.33 3.49e-03 GO:0010033 response to organic substance
1.18 3.68e-03 GO:0080090 regulation of primary metabolic process
1.30 4.68e-03 GO:0007399 nervous system development
1.37 6.16e-03 GO:0006793 phosphorus metabolic process
1.37 6.16e-03 GO:0006796 phosphate metabolic process
1.43 6.37e-03 GO:0006468 protein phosphorylation
1.43 6.70e-03 GO:2000026 regulation of multicellular organismal development
1.47 1.04e-02 GO:0009725 response to hormone stimulus
1.22 1.12e-02 GO:0048519 negative regulation of biological process
1.17 1.15e-02 GO:0031323 regulation of cellular metabolic process
1.20 1.68e-02 GO:0009889 regulation of biosynthetic process
1.23 2.23e-02 GO:0048523 negative regulation of cellular process
1.53 2.57e-02 GO:0051094 positive regulation of developmental process
1.27 2.98e-02 GO:0009653 anatomical structure morphogenesis
1.37 3.60e-02 GO:0016310 phosphorylation
1.42 3.99e-02 GO:0010628 positive regulation of gene expression
1.19 4.04e-02 GO:0031326 regulation of cellular biosynthetic process
1.16 4.37e-02 GO:0051179 localization
1.17 4.68e-02 GO:0060255 regulation of macromolecule metabolic process
1.22 4.72e-02 GO:0030154 cell differentiation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 5.01e-12 GO:0005737 cytoplasm
1.37 3.26e-11 GO:0044459 plasma membrane part
1.45 3.32e-08 GO:0005887 integral to plasma membrane
1.43 6.02e-08 GO:0031226 intrinsic to plasma membrane
1.53 1.18e-07 GO:0005626 insoluble fraction
1.53 3.76e-07 GO:0005624 membrane fraction
1.08 1.40e-06 GO:0005622 intracellular
1.08 1.43e-06 GO:0044424 intracellular part
1.40 1.03e-05 GO:0000267 cell fraction
1.13 7.52e-05 GO:0044444 cytoplasmic part
1.44 3.06e-04 GO:0031988 membrane-bounded vesicle
1.43 6.33e-04 GO:0016023 cytoplasmic membrane-bounded vesicle
1.41 9.09e-04 GO:0031982 vesicle
1.41 1.11e-03 GO:0031410 cytoplasmic vesicle
1.52 1.01e-02 GO:0043005 neuron projection
1.36 1.14e-02 GO:0005615 extracellular space
1.32 1.26e-02 GO:0005794 Golgi apparatus
1.07 2.62e-02 GO:0043227 membrane-bounded organelle
1.07 2.88e-02 GO:0043231 intracellular membrane-bounded organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.18 9.63e-13 GO:0005515 protein binding
1.08 6.51e-08 GO:0005488 binding
1.44 9.40e-06 GO:0001071 nucleic acid binding transcription factor activity
1.44 9.40e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.43 3.32e-03 GO:0043565 sequence-specific DNA binding
1.39 6.19e-03 GO:0019899 enzyme binding
1.85 1.42e-02 GO:0005085 guanyl-nucleotide exchange factor activity
1.74 1.76e-02 GO:0015291 secondary active transmembrane transporter activity
1.52 4.30e-02 GO:0022804 active transmembrane transporter activity
1.36 4.76e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor