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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: ZFP161.p2

Z-value: 2.461

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr14_+_100438095	35.954		EVL	Enah/Vasp-like
chr16_+_2039945	30.075	NM_004209	SYNGR3	synaptogyrin 3
chr16_+_58497993	28.676	NM_001130487	NDRG4	NDRG family member 4
chr11_-_33890931	27.614		LMO2	LIM domain only 2 (rhombotin-like 1)
chr16_+_58497628	27.611		NDRG4	NDRG family member 4
chr16_+_56225301	26.788		GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr17_+_44668034	26.134	NM_006178	NSF	N-ethylmaleimide-sensitive factor
chr8_+_26435339	25.922	NM_001386	DPYSL2	dihydropyrimidinase-like 2
chr16_+_56623266	25.097	NM_005954	MT3	metallothionein 3
chr16_+_58497548	23.678	NM_020465	NDRG4	NDRG family member 4
chr1_-_9884024	23.225		CLSTN1	calsyntenin 1
chr1_-_9884549	23.200	NM_001009566 NM_014944	CLSTN1	calsyntenin 1
chr17_+_43971868	22.633		MAPT	microtubule-associated protein tau
chr17_+_43971998	22.003		MAPT	microtubule-associated protein tau
chr22_-_39548448	21.910	NM_175709	CBX7	chromobox homolog 7
chr10_+_105037441	21.760		INA	internexin neuronal intermediate filament protein, alpha
chr20_+_17207669	21.167		PCSK2	proprotein convertase subtilisin/kexin type 2
chr19_-_19006868	20.962	NM_021267 NM_198207 NM_001492	CERS1 GDF1	ceramide synthase 1 growth differentiation factor 1
chr9_-_136024522	20.559	NM_001042368	RALGDS	ral guanine nucleotide dissociation stimulator
chrX_+_153665468	20.363		GDI1	GDP dissociation inhibitor 1
chr5_-_88179278	20.325	NM_001193350 NM_002397	MEF2C	myocyte enhancer factor 2C
chr11_-_33891258	20.019		LMO2	LIM domain only 2 (rhombotin-like 1)
chr11_-_6440631	19.723	NM_145689	APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr16_+_58498182	19.651		NDRG4	NDRG family member 4
chr8_+_26435466	19.350		DPYSL2	dihydropyrimidinase-like 2
chr16_+_58498216	19.259		NDRG4	NDRG family member 4
chr10_+_124220990	19.004	NM_002775	HTRA1	HtrA serine peptidase 1
chr5_-_11904127	18.811		CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr15_+_75287829	18.264	NM_001178111 NM_001178112 NM_138967	SCAMP5	secretory carrier membrane protein 5
chr17_+_43972014	18.085		MAPT	microtubule-associated protein tau
chr20_+_44657858	17.888		SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5
chr4_-_102268333	17.809		PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr17_+_43971655	17.729	NM_001123066 NM_001123067 NM_001203251 NM_001203252 NM_005910 NM_016834 NM_016835 NM_016841	MAPT	microtubule-associated protein tau
chr11_-_134281725	17.725	NM_018644 NM_054025	B3GAT1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr1_+_228675042	17.329	NM_001010858	RNF187	ring finger protein 187
chr11_-_6440288	17.302	NM_001164	APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr4_-_1242742	17.281		CTBP1	C-terminal binding protein 1
chrX_+_38420690	16.982	NM_004615	TSPAN7	tetraspanin 7
chr3_+_142838596	16.924	NM_004267	CHST2	carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr10_+_111985628	16.766	NM_005962	MXI1	MAX interactor 1
chr5_-_11903964	16.686	NM_001332	CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr6_-_6007632	16.000	NM_016588	NRN1	neuritin 1
chr17_+_40118696	15.884	NM_033133	CNP	2',3'-cyclic nucleotide 3' phosphodiesterase
chr4_+_158141735	15.598	NM_000826 NM_001083619 NM_001083620	GRIA2	glutamate receptor, ionotropic, AMPA 2
chr1_-_20812727	15.549	NM_018584	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr7_+_45614081	15.364	NM_021116	ADCY1	adenylate cyclase 1 (brain)
chr13_-_36705432	15.350		DCLK1	doublecortin-like kinase 1
chr5_-_88178964	15.272		MEF2C	myocyte enhancer factor 2C
chr20_+_17207680	15.239		PCSK2	proprotein convertase subtilisin/kexin type 2
chr20_+_44657812	14.570	NM_020708	SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5
chr19_+_47104559	14.456		CALM3	calmodulin 3 (phosphorylase kinase, delta)
chr3_-_127541975	14.365	NM_001003794	MGLL	monoglyceride lipase
chr7_+_153584383	14.302	NM_001039350	DPP6	dipeptidyl-peptidase 6
chr16_+_30194730	14.263	NM_001193333 NM_007074	CORO1A	coronin, actin binding protein, 1A
chrX_+_153665258	14.223	NM_001493	GDI1	GDP dissociation inhibitor 1
chr9_+_34958320	14.198		KIAA1045	KIAA1045
chr16_+_30194925	14.176		CORO1A	coronin, actin binding protein, 1A
chr12_-_124457099	14.051	NM_025140	CCDC92	coiled-coil domain containing 92
chr11_+_121322848	14.014	NM_003105	SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr12_-_121734543	14.007	NM_172226	CAMKK2	calcium/calmodulin-dependent protein kinase kinase 2, beta
chr22_-_39152008	13.912	NM_001199579 NM_015374	SUN2	Sad1 and UNC84 domain containing 2
chr7_-_44365019	13.781	NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084	CAMK2B	calcium/calmodulin-dependent protein kinase II beta
chr16_+_56225250	13.762	NM_020988 NM_138736	GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr22_-_39268214	13.706		CBX6	chromobox homolog 6
chr9_+_137967401	13.585		OLFM1	olfactomedin 1
chr13_+_113622758	13.428		MCF2L	MCF.2 cell line derived transforming sequence-like
chr10_-_73611005	13.368		PSAP	prosaposin
chr4_-_176923480	13.189		GPM6A	glycoprotein M6A
chr15_+_91643429	13.148	NM_014848	SV2B	synaptic vesicle glycoprotein 2B
chr11_-_125366048	13.069	NM_005103 NM_022549	FEZ1	fasciculation and elongation protein zeta 1 (zygin I)
chr11_+_46368881	13.030	NM_001199266 NM_001199267 NM_001199268 NM_003646	DGKZ	diacylglycerol kinase, zeta
chr11_-_1593149	12.983	NM_004420	DUSP8	dual specificity phosphatase 8
chr9_+_130374466	12.821	NM_001032221 NM_003165	STXBP1	syntaxin binding protein 1
chr20_+_57464156	12.788		GNAS	GNAS complex locus
chr8_-_125740650	12.758	NM_014751	MTSS1	metastasis suppressor 1
chr10_+_11060105	12.649		CELF2	CUGBP, Elav-like family member 2
chr20_+_17207596	12.610	NM_001201529 NM_002594	PCSK2	proprotein convertase subtilisin/kexin type 2
chr12_+_13197284	12.560	NM_020853	KIAA1467	KIAA1467
chr8_+_1922030	12.540	NM_014867	KBTBD11	kelch repeat and BTB (POZ) domain containing 11
chr12_-_121734474	12.290		CAMKK2	calcium/calmodulin-dependent protein kinase kinase 2, beta
chr22_-_39268169	12.287		CBX6	chromobox homolog 6
chr11_-_33891361	12.248	NM_001142316	LMO2	LIM domain only 2 (rhombotin-like 1)
chr22_-_45636760	12.239		KIAA0930	KIAA0930
chr3_-_133614421	12.237	NM_016577	RAB6B	RAB6B, member RAS oncogene family
chr9_-_139922705	12.188	NM_001606	ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2
chr19_+_47104490	12.088	NM_005184	CALM3	calmodulin 3 (phosphorylase kinase, delta)
chr18_-_74844762	12.060	NM_001025100 NM_001025101	MBP	myelin basic protein
chr8_-_144241918	11.986	NM_001130478	LY6H	lymphocyte antigen 6 complex, locus H
chr3_+_50712671	11.818	NM_004947	DOCK3	dedicator of cytokinesis 3
chr22_-_39151979	11.775		SUN2	Sad1 and UNC84 domain containing 2
chr9_+_137967088	11.697	NM_014279 NM_006334	OLFM1	olfactomedin 1
chr9_-_132805456	11.690	NM_015033	FNBP1	formin binding protein 1
chr1_+_204797774	11.681	NM_001005388 NM_001005389 NM_001160332 NM_001160333 NM_015090	NFASC	neurofascin
chr17_+_79651052	11.611
chr4_-_5894695	11.516	NM_001014809	CRMP1	collapsin response mediator protein 1
chr19_-_42498320	11.503	NM_152296	ATP1A3	ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr22_-_39268230	11.460	NM_014292	CBX6	chromobox homolog 6
chr10_-_104179468	11.451		PSD	pleckstrin and Sec7 domain containing
chr6_-_13486382	11.432	NM_001242628	GFOD1	glucose-fructose oxidoreductase domain containing 1
chr14_+_105780903	11.273		PACS2	phosphofurin acidic cluster sorting protein 2
chr4_-_1242882	11.269	NM_001012614 NM_001328	CTBP1	C-terminal binding protein 1
chr22_-_20104695	11.179		TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr9_+_137967366	11.160		OLFM1	olfactomedin 1
chr19_-_5340700	11.113	NM_002850 NM_130853 NM_130854 NM_130855	PTPRS	protein tyrosine phosphatase, receptor type, S
chr14_-_93651242	11.076	NM_022151	MOAP1	modulator of apoptosis 1
chr17_+_40118792	11.028		CNP	2',3'-cyclic nucleotide 3' phosphodiesterase
chr10_+_11059854	10.872	NM_006561	CELF2	CUGBP, Elav-like family member 2
chr11_-_64410785	10.847	NM_138734	NRXN2	neurexin 2
chr14_-_93651182	10.813		MOAP1	modulator of apoptosis 1
chr19_-_42498221	10.643		ATP1A3	ATPase, Na+/K+ transporting, alpha 3 polypeptide
chrX_-_107018889	10.616		TSC22D3	TSC22 domain family, member 3
chr9_+_131314669	10.455	NM_001130438 NM_001195532 NM_003127	SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
chr19_+_35634153	10.360	NM_022006	FXYD7	FXYD domain containing ion transport regulator 7
chr4_-_102268626	10.324	NM_000944 NM_001130691 NM_001130692	PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr8_-_144241678	10.298		LY6H	lymphocyte antigen 6 complex, locus H
chr10_+_11060069	10.154		CELF2	CUGBP, Elav-like family member 2
chrX_-_107019001	10.153	NM_198057	TSC22D3	TSC22 domain family, member 3
chr20_+_11871364	10.152	NM_181443	BTBD3	BTB (POZ) domain containing 3
chr22_+_32340592	10.146		YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr17_+_73043319	10.125		KCTD2	potassium channel tetramerisation domain containing 2
chr13_+_113623496	10.079	NM_001112732	MCF2L	MCF.2 cell line derived transforming sequence-like
chr9_-_139922595	10.043		ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2
chr4_+_6784453	9.876	NM_001100590 NM_014743	KIAA0232	KIAA0232
chr20_+_57466721	9.803		GNAS	GNAS complex locus
chrX_-_153362979	9.777		MECP2 LOC728653	methyl CpG binding protein 2 (Rett syndrome) uncharacterized LOC728653
chrX_-_137793394	9.769		FGF13	fibroblast growth factor 13
chr9_+_103235634	9.752		TMEFF1	transmembrane protein with EGF-like and two follistatin-like domains 1
chr1_+_84543629	9.566	NM_002731 NM_207578	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr2_+_207308280	9.555	NM_003812	ADAM23	ADAM metallopeptidase domain 23
chr4_-_109684053	9.546	NM_001146590 NM_001146627 NM_031279	AGXT2L1	alanine-glyoxylate aminotransferase 2-like 1
chr1_-_32229635	9.519	NM_001703	BAI2	brain-specific angiogenesis inhibitor 2
chr15_-_38856830	9.486	NM_001128602 NM_005739	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr19_-_1885431	9.475		FAM108A1	family with sequence similarity 108, member A1
chr17_-_78450247	9.380	NM_002522	NPTX1	neuronal pentraxin I
chr12_+_121078421	9.295	NM_001033677	CABP1	calcium binding protein 1
chr17_-_57184034	9.176		TRIM37	tripartite motif containing 37
chr17_-_57184174	9.171	NM_001005207 NM_015294	TRIM37	tripartite motif containing 37
chr19_-_1885375	9.053		FAM108A1	family with sequence similarity 108, member A1
chr11_+_63448868	9.023	NM_006054 NM_201428 NM_201429 NM_201430	RTN3	reticulon 3
chr10_-_73611041	9.020		PSAP	prosaposin
chr4_+_6784487	8.916		KIAA0232	KIAA0232
chr19_-_1885485	8.851	NM_001130111 NM_031213	FAM108A1	family with sequence similarity 108, member A1
chr19_-_1885462	8.790		FAM108A1	family with sequence similarity 108, member A1
chr4_+_6784462	8.700		KIAA0232	KIAA0232
chr3_-_127541160	8.583	NM_007283	MGLL	monoglyceride lipase
chr12_-_99038401	8.576	NM_153687 NM_201612 NM_201613	IKBIP	IKBKB interacting protein
chr20_+_57466509	8.525		GNAS	GNAS complex locus
chr13_-_77460432	8.512	NM_138444	KCTD12	potassium channel tetramerisation domain containing 12
chr19_+_35521591	8.464	NM_001037 NM_199037	SCN1B	sodium channel, voltage-gated, type I, beta
chr2_+_79740059	8.460	NM_001164883 NM_004389	CTNNA2	catenin (cadherin-associated protein), alpha 2
chr16_+_6533758	8.418		RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr5_+_76506705	8.391	NM_001029851 NM_001029852 NM_001029853 NM_001029854 NM_003719	PDE8B	phosphodiesterase 8B
chr1_-_200992824	8.383	NM_001252100 NM_001252102 NM_001252103 NM_017596	KIF21B	kinesin family member 21B
chr7_-_55640070	8.350		VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1
chr14_+_105781180	8.321		PACS2	phosphofurin acidic cluster sorting protein 2
chr4_+_166128823	8.266		KLHL2	kelch-like 2, Mayven (Drosophila)
chr17_+_73043154	8.260	NM_015353	KCTD2	potassium channel tetramerisation domain containing 2
chr11_-_695069	8.235		DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)
chr22_-_20104745	8.208	NM_022727 NM_182984	TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr9_+_34958171	8.194	NM_015297	KIAA1045	KIAA1045
chr2_+_11052062	8.188	NM_002236	KCNF1	potassium voltage-gated channel, subfamily F, member 1
chr1_-_241520384	8.175		RGS7	regulator of G-protein signaling 7
chr12_+_112451229	8.172
chr16_-_1832576	8.113	NM_080861	SPSB3	splA/ryanodine receptor domain and SOCS box containing 3
chr4_+_71859391	8.034		DCK	deoxycytidine kinase
chr10_+_104179570	8.034	NM_024326	FBXL15	F-box and leucine-rich repeat protein 15
chr13_-_77901176	8.032	NM_015057	MYCBP2	MYC binding protein 2
chr18_-_74844710	7.985		MBP	myelin basic protein
chr16_-_1832304	7.982		SPSB3	splA/ryanodine receptor domain and SOCS box containing 3
chr14_-_60097314	7.949		RTN1	reticulon 1
chr13_-_36705513	7.935	NM_004734	DCLK1	doublecortin-like kinase 1
chr12_+_108956293	7.895	NM_014301 NM_213595	ISCU	iron-sulfur cluster scaffold homolog (E. coli)
chr7_-_150974179	7.881	NM_003078	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr20_+_20348744	7.874	NM_002196	INSM1	insulinoma-associated 1
chr9_-_135996287	7.827	NM_006266	RALGDS	ral guanine nucleotide dissociation stimulator
chr1_+_226736500	7.801	NM_001003665	C1orf95	chromosome 1 open reading frame 95
chr3_+_23987514	7.768	NM_001145425	NR1D2	nuclear receptor subfamily 1, group D, member 2
chr16_-_4852571	7.740	NM_024589	ROGDI	rogdi homolog (Drosophila)
chr4_-_15656944	7.719		FBXL5	F-box and leucine-rich repeat protein 5
chr4_+_41362750	7.715	NM_001112717 NM_001112718 NM_014988	LIMCH1	LIM and calponin homology domains 1
chr7_-_55640104	7.698		VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1
chr10_-_88854686	7.668	NM_005271	GLUD1	glutamate dehydrogenase 1
chr17_+_2240795	7.660	NM_014853 NM_001098509	SGSM2	small G protein signaling modulator 2
chr4_-_83351294	7.603	NM_001207000 NM_031372	HNRPDL	heterogeneous nuclear ribonucleoprotein D-like
chrX_+_51927918	7.592	NM_001098800 NM_001242362 NM_030801 NM_177535 NM_177537	MAGED4 MAGED4B	melanoma antigen family D, 4 melanoma antigen family D, 4B
chr14_-_60097223	7.578		RTN1	reticulon 1
chr11_-_64511550	7.563	NM_001098671	RASGRP2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr2_+_234263141	7.529	NM_152879	DGKD	diacylglycerol kinase, delta 130kDa
chr3_-_56502364	7.477	NM_015576	ERC2	ELKS/RAB6-interacting/CAST family member 2
chr1_-_29508263	7.461		SRSF4	serine/arginine-rich splicing factor 4
chr12_-_112450914	7.436	NM_001193453 NM_001193531 NM_138341	LOC728543 TMEM116	uncharacterized LOC728543 transmembrane protein 116
chr7_-_55640131	7.392		VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1
chr9_+_77703412	7.368		OSTF1	osteoclast stimulating factor 1
chr8_-_144241725	7.345	NM_001135655	LY6H	lymphocyte antigen 6 complex, locus H
chr19_+_47104389	7.337		CALM3	calmodulin 3 (phosphorylase kinase, delta)
chr1_-_241520467	7.280	NM_002924	RGS7	regulator of G-protein signaling 7
chr1_+_6845381	7.258	NM_001195563 NM_001242701 NM_015215	CAMTA1	calmodulin binding transcription activator 1
chr9_-_92112887	7.220		SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr3_+_40351193	7.198		EIF1B	eukaryotic translation initiation factor 1B
chr16_-_5083933	7.183	NM_016256	NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.27	2.35e-25	GO:0050794	regulation of cellular process
1.25	4.23e-24	GO:0050789	regulation of biological process
1.75	6.18e-24	GO:0007399	nervous system development
1.24	5.01e-23	GO:0065007	biological regulation
1.39	3.14e-20	GO:0023052	signaling
1.14	6.86e-20	GO:0009987	cellular process
1.62	3.43e-18	GO:0023051	regulation of signaling
1.79	1.72e-17	GO:0006793	phosphorus metabolic process
1.79	1.72e-17	GO:0006796	phosphate metabolic process
1.54	6.31e-16	GO:0006464	protein modification process
1.78	5.69e-15	GO:0022008	neurogenesis
1.36	9.35e-15	GO:0007165	signal transduction
1.80	9.87e-15	GO:0048699	generation of neurons
1.50	3.42e-14	GO:0043412	macromolecule modification
1.60	1.33e-13	GO:0035556	intracellular signal transduction
1.57	3.51e-13	GO:0009966	regulation of signal transduction
1.76	6.53e-13	GO:0016310	phosphorylation
1.22	3.04e-12	GO:0044237	cellular metabolic process
1.45	3.36e-12	GO:0030154	cell differentiation
1.32	6.24e-12	GO:0051179	localization
1.30	6.78e-12	GO:0032502	developmental process
1.44	8.72e-12	GO:0048869	cellular developmental process
1.78	9.09e-12	GO:0006468	protein phosphorylation
1.32	2.51e-11	GO:0007275	multicellular organismal development
1.35	8.37e-11	GO:0048731	system development
1.32	1.80e-10	GO:0048856	anatomical structure development
1.80	2.18e-10	GO:0007167	enzyme linked receptor protein signaling pathway
1.75	4.99e-10	GO:0030182	neuron differentiation
1.29	5.36e-10	GO:0031323	regulation of cellular metabolic process
1.29	7.44e-10	GO:0080090	regulation of primary metabolic process
1.27	8.06e-10	GO:0019222	regulation of metabolic process
1.37	1.05e-09	GO:0048519	negative regulation of biological process
1.63	1.30e-09	GO:0048468	cell development
1.82	1.43e-09	GO:0048666	neuron development
1.26	1.45e-09	GO:0051716	cellular response to stimulus
1.42	1.61e-09	GO:0048583	regulation of response to stimulus
1.57	3.60e-09	GO:0010646	regulation of cell communication
1.38	4.93e-09	GO:0048523	negative regulation of cellular process
1.62	7.29e-09	GO:0050793	regulation of developmental process
1.84	1.07e-08	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.85	1.21e-08	GO:0019226	transmission of nerve impulse
1.85	1.21e-08	GO:0035637	multicellular organismal signaling
1.29	1.39e-08	GO:0060255	regulation of macromolecule metabolic process
1.41	2.34e-08	GO:0007166	cell surface receptor linked signaling pathway
1.49	4.34e-08	GO:0051239	regulation of multicellular organismal process
1.82	5.97e-08	GO:0031175	neuron projection development
1.86	1.43e-07	GO:0007268	synaptic transmission
1.86	1.43e-07	GO:0048667	cell morphogenesis involved in neuron differentiation
1.68	1.55e-07	GO:0045595	regulation of cell differentiation
1.29	1.98e-07	GO:0051234	establishment of localization
1.32	2.67e-07	GO:0048522	positive regulation of cellular process
1.84	2.74e-07	GO:0023057	negative regulation of signaling
1.69	2.86e-07	GO:0030030	cell projection organization
1.84	3.22e-07	GO:0010648	negative regulation of cell communication
1.31	3.37e-07	GO:0010468	regulation of gene expression
1.77	4.35e-07	GO:0007417	central nervous system development
1.83	4.43e-07	GO:0048812	neuron projection morphogenesis
1.28	7.06e-07	GO:0006810	transport
1.84	8.11e-07	GO:0007409	axonogenesis
1.76	9.23e-07	GO:0048858	cell projection morphogenesis
1.31	1.03e-06	GO:0044267	cellular protein metabolic process
1.15	1.25e-06	GO:0008152	metabolic process
1.76	1.25e-06	GO:0000904	cell morphogenesis involved in differentiation
1.61	1.30e-06	GO:2000026	regulation of multicellular organismal development
1.29	1.49e-06	GO:0048518	positive regulation of biological process
1.84	1.50e-06	GO:0009968	negative regulation of signal transduction
1.75	1.64e-06	GO:0032990	cell part morphogenesis
1.31	1.77e-06	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.21	1.98e-06	GO:0044260	cellular macromolecule metabolic process
1.84	2.76e-06	GO:0007264	small GTPase mediated signal transduction
2.13	2.89e-06	GO:0048011	nerve growth factor receptor signaling pathway
1.25	3.21e-06	GO:0016043	cellular component organization
1.29	3.51e-06	GO:0009889	regulation of biosynthetic process
1.63	3.74e-06	GO:0009719	response to endogenous stimulus
1.51	4.20e-06	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.30	4.69e-06	GO:0010556	regulation of macromolecule biosynthetic process
1.16	5.90e-06	GO:0044238	primary metabolic process
1.28	6.20e-06	GO:0031326	regulation of cellular biosynthetic process
1.43	8.09e-06	GO:0051641	cellular localization
1.28	8.85e-06	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.88	1.20e-05	GO:0045597	positive regulation of cell differentiation
1.49	1.34e-05	GO:0032879	regulation of localization
1.70	1.41e-05	GO:0048585	negative regulation of response to stimulus
1.47	2.01e-05	GO:0032268	regulation of cellular protein metabolic process
1.58	2.03e-05	GO:0019220	regulation of phosphate metabolic process
1.58	2.03e-05	GO:0051174	regulation of phosphorus metabolic process
1.63	2.83e-05	GO:0000902	cell morphogenesis
1.60	3.75e-05	GO:0032989	cellular component morphogenesis
1.45	3.81e-05	GO:0051246	regulation of protein metabolic process
1.30	5.32e-05	GO:0065008	regulation of biological quality
1.58	5.48e-05	GO:0042325	regulation of phosphorylation
1.61	5.75e-05	GO:0010629	negative regulation of gene expression
1.92	5.87e-05	GO:0051960	regulation of nervous system development
1.26	6.69e-05	GO:0051171	regulation of nitrogen compound metabolic process
1.60	7.81e-05	GO:0009725	response to hormone stimulus
1.29	9.08e-05	GO:0006355	regulation of transcription, DNA-dependent
1.22	1.01e-04	GO:0071840	cellular component organization or biogenesis
1.51	1.02e-04	GO:0051128	regulation of cellular component organization
1.46	1.07e-04	GO:0009892	negative regulation of metabolic process
1.58	1.08e-04	GO:0001932	regulation of protein phosphorylation
1.29	1.09e-04	GO:0042221	response to chemical stimulus
1.26	1.10e-04	GO:0071842	cellular component organization at cellular level
1.95	1.33e-04	GO:0050767	regulation of neurogenesis
1.62	1.57e-04	GO:0051253	negative regulation of RNA metabolic process
1.99	1.60e-04	GO:0071375	cellular response to peptide hormone stimulus
1.63	1.68e-04	GO:0045892	negative regulation of transcription, DNA-dependent
1.94	1.92e-04	GO:0000165	MAPKKK cascade
1.28	2.20e-04	GO:0051252	regulation of RNA metabolic process
1.68	2.38e-04	GO:0051094	positive regulation of developmental process
1.35	2.65e-04	GO:0009653	anatomical structure morphogenesis
1.49	3.02e-04	GO:0031399	regulation of protein modification process
1.47	3.36e-04	GO:0040011	locomotion
1.37	3.62e-04	GO:0033036	macromolecule localization
1.45	5.49e-04	GO:0010605	negative regulation of macromolecule metabolic process
1.40	6.89e-04	GO:0051649	establishment of localization in cell
1.46	7.06e-04	GO:0006351	transcription, DNA-dependent
1.53	7.32e-04	GO:0010558	negative regulation of macromolecule biosynthetic process
1.55	8.31e-04	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.54	8.39e-04	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.66	8.39e-04	GO:0032583	regulation of gene-specific transcription
2.62	8.93e-04	GO:0030178	negative regulation of Wnt receptor signaling pathway
2.35	9.19e-04	GO:0031098	stress-activated protein kinase signaling cascade
2.04	1.03e-03	GO:0032869	cellular response to insulin stimulus
1.74	1.07e-03	GO:0043434	response to peptide hormone stimulus
1.75	1.08e-03	GO:0007411	axon guidance
1.34	1.19e-03	GO:0065009	regulation of molecular function
1.51	1.20e-03	GO:0009890	negative regulation of biosynthetic process
1.38	1.47e-03	GO:0010604	positive regulation of macromolecule metabolic process
1.79	1.53e-03	GO:0009205	purine ribonucleoside triphosphate metabolic process
2.18	1.59e-03	GO:0008286	insulin receptor signaling pathway
1.53	1.71e-03	GO:0051172	negative regulation of nitrogen compound metabolic process
2.60	1.72e-03	GO:0034142	toll-like receptor 4 signaling pathway
1.70	1.74e-03	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.65	1.77e-03	GO:0007243	intracellular protein kinase cascade
1.65	1.77e-03	GO:0023014	signal transduction via phosphorylation event
1.78	1.78e-03	GO:0009199	ribonucleoside triphosphate metabolic process
1.36	2.15e-03	GO:0009893	positive regulation of metabolic process
2.45	2.16e-03	GO:0002221	pattern recognition receptor signaling pathway
2.48	2.25e-03	GO:0002224	toll-like receptor signaling pathway
1.66	2.26e-03	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.75	2.35e-03	GO:0032870	cellular response to hormone stimulus
1.77	2.39e-03	GO:0009144	purine nucleoside triphosphate metabolic process
1.72	2.56e-03	GO:0071495	cellular response to endogenous stimulus
1.49	2.87e-03	GO:0031327	negative regulation of cellular biosynthetic process
1.74	3.09e-03	GO:0060284	regulation of cell development
1.93	3.15e-03	GO:0045664	regulation of neuron differentiation
1.75	3.17e-03	GO:0009141	nucleoside triphosphate metabolic process
1.77	3.25e-03	GO:0051270	regulation of cellular component movement
1.23	3.35e-03	GO:0071841	cellular component organization or biogenesis at cellular level
1.45	3.36e-03	GO:0046907	intracellular transport
1.87	3.61e-03	GO:0032868	response to insulin stimulus
2.70	4.48e-03	GO:0034138	toll-like receptor 3 signaling pathway
2.37	5.04e-03	GO:0002758	innate immune response-activating signal transduction
1.70	5.15e-03	GO:0009259	ribonucleotide metabolic process
1.67	5.20e-03	GO:0007420	brain development
1.61	5.24e-03	GO:0072521	purine-containing compound metabolic process
2.21	5.43e-03	GO:0007265	Ras protein signal transduction
1.49	5.49e-03	GO:0071310	cellular response to organic substance
1.37	5.49e-03	GO:0008104	protein localization
1.70	5.89e-03	GO:0044057	regulation of system process
2.51	6.17e-03	GO:0008063	Toll signaling pathway
3.64	6.80e-03	GO:0021954	central nervous system neuron development
1.41	6.96e-03	GO:0031324	negative regulation of cellular metabolic process
2.92	7.23e-03	GO:0051403	stress-activated MAPK cascade
1.55	8.56e-03	GO:0006753	nucleoside phosphate metabolic process
1.55	8.56e-03	GO:0009117	nucleotide metabolic process
2.32	8.61e-03	GO:0002218	activation of innate immune response
2.56	8.80e-03	GO:0034130	toll-like receptor 1 signaling pathway
2.56	8.80e-03	GO:0034134	toll-like receptor 2 signaling pathway
1.69	9.38e-03	GO:0009150	purine ribonucleotide metabolic process
1.33	1.12e-02	GO:0010033	response to organic substance
1.34	1.19e-02	GO:0031325	positive regulation of cellular metabolic process
2.02	1.20e-02	GO:0001666	response to hypoxia
1.63	1.40e-02	GO:0090066	regulation of anatomical structure size
1.76	1.48e-02	GO:0009166	nucleotide catabolic process
1.63	1.58e-02	GO:0051056	regulation of small GTPase mediated signal transduction
1.61	1.60e-02	GO:0006163	purine nucleotide metabolic process
1.37	1.60e-02	GO:0007154	cell communication
1.28	1.65e-02	GO:0006996	organelle organization
2.02	1.92e-02	GO:0006184	GTP catabolic process
1.71	2.17e-02	GO:0034655	nucleobase, nucleoside, nucleotide and nucleic acid catabolic process
1.71	2.17e-02	GO:0034656	nucleobase, nucleoside and nucleotide catabolic process
1.68	2.22e-02	GO:0007610	behavior
1.77	2.38e-02	GO:0006195	purine nucleotide catabolic process
1.80	2.40e-02	GO:0009261	ribonucleotide catabolic process
1.66	2.70e-02	GO:0051093	negative regulation of developmental process
1.75	2.73e-02	GO:0072523	purine-containing compound catabolic process
1.58	2.79e-02	GO:0016477	cell migration
2.05	2.84e-02	GO:0030111	regulation of Wnt receptor signaling pathway
2.42	2.94e-02	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
2.51	3.21e-02	GO:0002756	MyD88-independent toll-like receptor signaling pathway
1.84	3.21e-02	GO:0044087	regulation of cellular component biogenesis
1.14	3.41e-02	GO:0043170	macromolecule metabolic process
1.88	3.56e-02	GO:0006913	nucleocytoplasmic transport
1.78	3.79e-02	GO:0009154	purine ribonucleotide catabolic process
1.41	4.28e-02	GO:0007267	cell-cell signaling
1.94	4.34e-02	GO:0046039	GTP metabolic process
1.13	4.67e-02	GO:0032501	multicellular organismal process
1.71	4.72e-02	GO:0030334	regulation of cell migration
1.53	4.93e-02	GO:0048870	cell motility
1.53	4.93e-02	GO:0051674	localization of cell
1.86	4.98e-02	GO:0051169	nuclear transport

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.13	4.10e-19	GO:0044424	intracellular part
1.13	1.76e-18	GO:0005622	intracellular
1.18	1.01e-15	GO:0005737	cytoplasm
1.14	8.44e-14	GO:0043226	organelle
1.14	3.23e-13	GO:0043229	intracellular organelle
1.15	2.16e-12	GO:0043227	membrane-bounded organelle
1.15	5.40e-12	GO:0043231	intracellular membrane-bounded organelle
1.19	2.57e-08	GO:0005634	nucleus
1.17	1.79e-07	GO:0044444	cytoplasmic part
1.54	1.42e-06	GO:0031982	vesicle
1.48	1.73e-06	GO:0005794	Golgi apparatus
1.77	1.80e-06	GO:0045202	synapse
1.53	6.16e-06	GO:0031410	cytoplasmic vesicle
1.74	7.90e-06	GO:0043005	neuron projection
1.30	1.36e-05	GO:0005829	cytosol
1.04	1.71e-05	GO:0044464	cell part
1.04	1.79e-05	GO:0005623	cell
1.51	3.55e-05	GO:0016023	cytoplasmic membrane-bounded vesicle
1.50	4.27e-05	GO:0031988	membrane-bounded vesicle
1.56	7.21e-05	GO:0044431	Golgi apparatus part
2.05	7.34e-05	GO:0030424	axon
1.57	5.62e-04	GO:0000139	Golgi membrane
2.51	8.55e-04	GO:0033267	axon part
1.70	1.55e-03	GO:0044456	synapse part
1.44	2.60e-03	GO:0015630	microtubule cytoskeleton
1.13	2.77e-03	GO:0044446	intracellular organelle part
2.20	4.16e-03	GO:0019717	synaptosome
1.13	4.63e-03	GO:0044422	organelle part
1.38	5.99e-03	GO:0005626	insoluble fraction
1.30	6.08e-03	GO:0005654	nucleoplasm
1.66	7.18e-03	GO:0005874	microtubule
2.09	1.80e-02	GO:0019898	extrinsic to membrane
1.35	2.74e-02	GO:0005624	membrane fraction
1.34	2.76e-02	GO:0042995	cell projection

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.23	9.24e-21	GO:0005515	protein binding
1.12	3.22e-19	GO:0005488	binding
1.76	4.05e-12	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.72	8.13e-12	GO:0016301	kinase activity
1.37	1.34e-10	GO:0000166	nucleotide binding
1.78	2.22e-10	GO:0004672	protein kinase activity
1.93	2.60e-10	GO:0004674	protein serine/threonine kinase activity
1.39	3.05e-09	GO:0017076	purine nucleotide binding
1.59	3.65e-09	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.39	5.49e-09	GO:0032553	ribonucleotide binding
1.39	5.49e-09	GO:0032555	purine ribonucleotide binding
1.38	1.38e-08	GO:0035639	purine ribonucleoside triphosphate binding
1.60	1.40e-07	GO:0019899	enzyme binding
1.75	1.49e-06	GO:0019904	protein domain specific binding
1.16	1.55e-05	GO:0003824	catalytic activity
1.34	3.45e-05	GO:0030554	adenyl nucleotide binding
1.44	5.43e-05	GO:0001071	nucleic acid binding transcription factor activity
1.44	5.43e-05	GO:0003700	sequence-specific DNA binding transcription factor activity
1.34	6.63e-05	GO:0032559	adenyl ribonucleotide binding
1.42	8.81e-05	GO:0030528	transcription regulator activity
1.33	1.10e-04	GO:0005524	ATP binding
1.81	1.15e-04	GO:0008134	transcription factor binding
1.31	1.41e-04	GO:0016740	transferase activity
1.60	3.91e-04	GO:0060589	nucleoside-triphosphatase regulator activity
1.69	7.91e-04	GO:0042578	phosphoric ester hydrolase activity
1.58	1.13e-03	GO:0030695	GTPase regulator activity
1.85	2.38e-03	GO:0003924	GTPase activity
1.98	2.49e-03	GO:0004721	phosphoprotein phosphatase activity
1.76	4.43e-03	GO:0016791	phosphatase activity
2.18	9.70e-03	GO:0005057	receptor signaling protein activity
1.58	1.05e-02	GO:0019001	guanyl nucleotide binding
1.58	1.05e-02	GO:0032561	guanyl ribonucleotide binding
1.96	1.06e-02	GO:0022843	voltage-gated cation channel activity
1.57	1.85e-02	GO:0005525	GTP binding
1.40	3.33e-02	GO:0043565	sequence-specific DNA binding
1.20	3.99e-02	GO:0003677	DNA binding