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• Activity deltas table
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Motif ID: ZNF143.p2

Z-value: 6.550

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_+_1723212	134.977	NM_006342	TACC3	transforming, acidic coiled-coil containing protein 3
chr17_-_47492215	128.301		PHB	prohibitin
chr20_-_32891075	116.312	NM_000687	AHCY	adenosylhomocysteinase
chr12_+_56498324	109.260		PA2G4	proliferation-associated 2G4, 38kDa
chr12_+_56498347	107.642		PA2G4	proliferation-associated 2G4, 38kDa
chr15_+_40453263	107.174		BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)
chr15_+_40453209	104.125	NM_001211	BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)
chr19_-_48673559	101.616	NM_000234	LIG1	ligase I, DNA, ATP-dependent
chr12_+_32832128	96.640	NM_005690 NM_012062 NM_012063	DNM1L	dynamin 1-like
chr1_-_54304107	96.112	NM_001168551 NM_018087	TMEM48	transmembrane protein 48
chrY_+_59213948	95.454	NM_001145149 NM_001185183 NM_005638	VAMP7	vesicle-associated membrane protein 7
chrX_+_155110942	93.306	NM_001145149 NM_001185183 NM_005638	VAMP7	vesicle-associated membrane protein 7
chr12_+_56498102	90.909	NM_006191	PA2G4	proliferation-associated 2G4, 38kDa
chr17_-_47492216	89.496	NM_002634	PHB	prohibitin
chr11_-_82997376	89.069	NM_021825	CCDC90B	coiled-coil domain containing 90B
chr12_+_56498414	87.077		PA2G4	proliferation-associated 2G4, 38kDa
chr12_+_32832209	80.578		DNM1L	dynamin 1-like
chr4_+_1723233	80.417		TACC3	transforming, acidic coiled-coil containing protein 3
chr11_-_82996898	80.222		CCDC90B	coiled-coil domain containing 90B
chr10_+_124913884	79.841		BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)
chr12_+_56498365	79.401		PA2G4	proliferation-associated 2G4, 38kDa
chr12_+_32832272	78.648		DNM1L	dynamin 1-like
chr13_-_50367027	77.435	NM_002267	KPNA3	karyopherin alpha 3 (importin alpha 4)
chr17_+_76210276	76.807	NM_001012270 NM_001012271 NM_001168	BIRC5	baculoviral IAP repeat containing 5
chr22_-_41682169	76.560		RANGAP1	Ran GTPase activating protein 1
chr22_+_30163351	76.385	NM_001003684 NM_013387	UQCR10	ubiquinol-cytochrome c reductase, complex III subunit X
chr1_+_45205533	75.597		KIF2C	kinesin family member 2C
chr1_+_224544590	74.775	NM_014184	CNIH4	cornichon homolog 4 (Drosophila)
chr22_-_41682187	72.457	NM_002883	RANGAP1	Ran GTPase activating protein 1
chr12_+_56498334	71.578		PA2G4	proliferation-associated 2G4, 38kDa
chr1_+_224544550	71.555		CNIH4	cornichon homolog 4 (Drosophila)
chr17_+_76210329	71.155		BIRC5	baculoviral IAP repeat containing 5
chr19_+_12917391	70.954		RNASEH2A	ribonuclease H2, subunit A
chr9_-_116172658	70.792		POLE3	polymerase (DNA directed), epsilon 3 (p17 subunit)
chr1_+_224544597	69.452		CNIH4	cornichon homolog 4 (Drosophila)
chr1_+_45205558	68.921		KIF2C	kinesin family member 2C
chr4_-_2965036	68.308		NOP14	NOP14 nucleolar protein homolog (yeast)
chr1_-_54303933	67.525		TMEM48	transmembrane protein 48
chr17_-_5322982	67.285	NM_002532	NUP88	nucleoporin 88kDa
chr19_+_54618789	66.037	NM_015629	PRPF31	PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
chr19_-_2456954	64.680	NM_032737	LMNB2	lamin B2
chr9_-_116172635	64.582		POLE3	polymerase (DNA directed), epsilon 3 (p17 subunit)
chr14_-_23398605	63.505	NM_001039619 NM_006109	PRMT5	protein arginine methyltransferase 5
chr14_-_23398563	63.454		PRMT5	protein arginine methyltransferase 5
chr12_-_122985471	63.405	NM_017612	ZCCHC8	zinc finger, CCHC domain containing 8
chr14_+_97263681	63.349	NM_003384	VRK1	vaccinia related kinase 1
chr12_+_53895376	62.805	NM_134324	TARBP2	TAR (HIV-1) RNA binding protein 2
chr1_+_156024516	61.736	NM_001145264 NM_014017	LAMTOR2	late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr20_-_47804903	60.382	NM_001037328 NM_004602 NM_017452 NM_017453 NM_017454	STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)
chr9_-_116172572	60.204		POLE3	polymerase (DNA directed), epsilon 3 (p17 subunit)
chr19_+_41257086	58.420		SNRPA	small nuclear ribonucleoprotein polypeptide A
chr4_-_2965091	56.930		NOP14	NOP14 nucleolar protein homolog (yeast)
chr3_+_133524671	56.114		SRPRB	signal recognition particle receptor, B subunit
chr7_-_150754934	55.608		CDK5	cyclin-dependent kinase 5
chr10_+_124913921	55.288		BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)
chr22_-_36925212	54.960		EIF3D	eukaryotic translation initiation factor 3, subunit D
chr11_+_64808375	54.897	NM_013299	SAC3D1	SAC3 domain containing 1
chr4_-_2965111	54.893	NM_003703	NOP14	NOP14 nucleolar protein homolog (yeast)
chr1_+_45205466	54.446	NM_006845	KIF2C	kinesin family member 2C
chr11_+_16760147	54.332	NM_014267	C11orf58	chromosome 11 open reading frame 58
chr1_-_197115566	54.280	NM_001206846 NM_018136	ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr3_+_133524636	54.122		SRPRB	signal recognition particle receptor, B subunit
chr20_-_48732479	53.980	NM_022442 NM_021988 NM_199144	UBE2V1	ubiquitin-conjugating enzyme E2 variant 1
chr7_-_99063763	53.953	NM_001198879 NM_001003713 NM_001003714 NM_001039178 NM_004889	ATP5J2-PTCD1 ATP5J2	ATP5J2-PTCD1 readthrough ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
chr8_-_144699716	53.946	NM_003313	TSTA3	tissue specific transplantation antigen P35B
chr17_+_30771520	53.666		PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr17_-_62777621	53.008		LOC146880	Rho GTPase activating protein 27 pseudogene
chr10_+_124913759	52.792	NM_001007793 NM_004725	BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)
chr12_-_96429296	52.709	NM_000895	LTA4H	leukotriene A4 hydrolase
chr7_-_150754979	52.558	NM_001164410 NM_004935	CDK5	cyclin-dependent kinase 5
chr11_+_16760175	52.503		C11orf58	chromosome 11 open reading frame 58
chr8_-_144699621	51.715		TSTA3	tissue specific transplantation antigen P35B
chr5_+_85913762	51.613	NM_001867	COX7C	cytochrome c oxidase subunit VIIc
chr11_+_64808395	51.042		SAC3D1	SAC3 domain containing 1
chr17_-_21117647	50.969		TMEM11	transmembrane protein 11
chr1_+_38158129	50.430	NM_018101	CDCA8	cell division cycle associated 8
chr16_-_12009734	50.350		GSPT1	G1 to S phase transition 1
chr12_-_96429397	50.101		LTA4H	leukotriene A4 hydrolase
chr22_-_36925138	49.976		EIF3D	eukaryotic translation initiation factor 3, subunit D
chr3_-_186524226	49.874	NM_002916	RFC4	replication factor C (activator 1) 4, 37kDa
chr8_-_144699695	49.831		TSTA3	tissue specific transplantation antigen P35B
chr10_-_13390018	49.805		SEPHS1	selenophosphate synthetase 1
chr22_-_36925270	49.716	NM_003753	EIF3D	eukaryotic translation initiation factor 3, subunit D
chr3_-_186524483	49.334	NM_181573	RFC4	replication factor C (activator 1) 4, 37kDa
chr1_-_67896081	49.196		SERBP1	SERPINE1 mRNA binding protein 1
chr19_+_12917409	48.595	NM_006397	RNASEH2A	ribonuclease H2, subunit A
chr1_+_156737315	48.417		PRCC	papillary renal cell carcinoma (translocation-associated)
chr11_-_60674039	47.890	NM_014502	PRPF19	PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)
chr16_-_31106049	47.876		VKORC1	vitamin K epoxide reductase complex, subunit 1
chr14_-_105487421	47.527	NM_017955 NM_145701	CDCA4	cell division cycle associated 4
chr17_+_66031814	47.418	NM_002266	KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr12_+_56435685	47.135	NM_001029	RPS26	ribosomal protein S26
chr11_-_64578017	46.899	NM_130800 NM_130801	MEN1	multiple endocrine neoplasia I
chr19_-_47354060	46.453	NM_004069 NM_021575	AP2S1	adaptor-related protein complex 2, sigma 1 subunit
chrX_+_48334400	46.426	NM_012280 NM_177439	FTSJ1	FtsJ homolog 1 (E. coli)
chr3_-_167452593	45.879	NM_007217 NM_145860 NM_145859	PDCD10	programmed cell death 10
chr17_+_66031885	45.604		KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr7_+_2394546	45.530		EIF3B	eukaryotic translation initiation factor 3, subunit B
chr22_-_36925175	44.751		EIF3D	eukaryotic translation initiation factor 3, subunit D
chr17_-_21117899	44.556	NM_003876	TMEM11	transmembrane protein 11
chr11_+_208529	44.553	NM_021932	RIC8A	resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
chr20_-_47804675	44.430		STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)
chr6_-_5004238	44.406	NM_006638	RPP40	ribonuclease P/MRP 40kDa subunit
chr5_+_137514416	44.289	NM_005733	KIF20A	kinesin family member 20A
chr1_-_67896098	43.938	NM_001018067 NM_001018068 NM_001018069 NM_015640	SERBP1	SERPINE1 mRNA binding protein 1
chr21_-_30445949	43.914		CCT8	chaperonin containing TCP1, subunit 8 (theta)
chr7_+_150755298	43.722	NM_001199692	SLC4A2	solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr5_+_85913755	43.511		COX7C	cytochrome c oxidase subunit VIIc
chr12_-_122985396	43.420		ZCCHC8	zinc finger, CCHC domain containing 8
chr21_-_30445913	43.272		CCT8	chaperonin containing TCP1, subunit 8 (theta)
chr9_-_116172951	43.219	NM_017443	POLE3	polymerase (DNA directed), epsilon 3 (p17 subunit)
chr17_-_21117479	43.129		TMEM11	transmembrane protein 11
chr10_+_124913862	43.057		BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)
chr7_-_96339074	42.847		SHFM1	split hand/foot malformation (ectrodactyly) type 1
chr8_-_63951353	41.875		GGH	gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr16_+_3074027	41.807	NM_001142350 NM_024339	THOC6	THO complex 6 homolog (Drosophila)
chr6_+_56954978	41.764		ZNF451	zinc finger protein 451
chr12_+_53895065	41.565		TARBP2	TAR (HIV-1) RNA binding protein 2
chr2_-_74756824	41.390		AUP1	ancient ubiquitous protein 1
chr5_+_137514753	41.317		KIF20A	kinesin family member 20A
chr2_-_242447919	41.212		STK25	serine/threonine kinase 25
chr1_+_156737273	41.039	NM_005973	PRCC	papillary renal cell carcinoma (translocation-associated)
chr9_+_116037955	40.992		PRPF4	PRP4 pre-mRNA processing factor 4 homolog (yeast)
chr12_+_88536045	40.950	NM_181783	TMTC3	transmembrane and tetratricopeptide repeat containing 3
chr7_+_2394428	40.892	NM_001037283 NM_003751	EIF3B	eukaryotic translation initiation factor 3, subunit B
chr2_-_132249946	40.603		MZT2A	mitotic spindle organizing protein 2A
chr11_-_64578176	40.469	NM_000244 NM_130799 NM_130802	MEN1	multiple endocrine neoplasia I
chr12_+_93861265	40.446	NM_014050 NM_172177	MRPL42	mitochondrial ribosomal protein L42
chr12_-_2986095	40.206		FOXM1	forkhead box M1
chr8_-_63951609	40.072	NM_003878	GGH	gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr7_+_2394508	39.897		EIF3B	eukaryotic translation initiation factor 3, subunit B
chr12_+_57881853	39.849		MARS	methionyl-tRNA synthetase
chr3_+_160117444	39.626		SMC4	structural maintenance of chromosomes 4
chr20_-_61847446	39.621	NM_017798	YTHDF1	YTH domain family, member 1
chr1_-_67896097	39.600		SERBP1	SERPINE1 mRNA binding protein 1
chr1_+_38158176	38.965		CDCA8	cell division cycle associated 8
chr12_+_104609501	38.963	NM_001093771	TXNRD1	thioredoxin reductase 1
chr1_-_67896066	38.700		SERBP1	SERPINE1 mRNA binding protein 1
chr2_+_130939781	38.572		MZT2B	mitotic spindle organizing protein 2B
chr19_+_3185860	38.245	NM_020170	NCLN	nicalin
chr12_-_57146081	38.191	NM_000946	PRIM1	primase, DNA, polypeptide 1 (49kDa)
chr11_+_61560352	38.139		FEN1	flap structure-specific endonuclease 1
chr11_+_747428	38.127	NM_006755	TALDO1	transaldolase 1
chr12_-_46663207	37.988	NM_001077484 NM_030674	SLC38A1	solute carrier family 38, member 1
chr6_+_56954801	37.973	NM_001031623 NM_015555	ZNF451	zinc finger protein 451
chr6_+_56954985	37.838		ZNF451	zinc finger protein 451
chr7_+_2394498	37.837		EIF3B	eukaryotic translation initiation factor 3, subunit B
chr16_+_67880784	37.806	NM_005796	NUTF2	nuclear transport factor 2
chr14_+_77924367	37.525	NM_012111	AHSA1	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr17_-_40950682	37.311	NM_001040431	CCDC56	coiled-coil domain containing 56
chr16_+_3074041	37.275		THOC6	THO complex 6 homolog (Drosophila)
chr1_+_244816349	37.230	NM_016076	PPPDE1	PPPDE peptidase domain containing 1
chr16_+_577833	37.017	NM_005632	SOLH	small optic lobes homolog (Drosophila)
chr12_+_64798050	37.005	NM_007235	XPOT	exportin, tRNA (nuclear export receptor for tRNAs)
chr22_+_21922020	36.823		UBE2L3	ubiquitin-conjugating enzyme E2L 3
chr11_+_747424	36.391		TALDO1	transaldolase 1
chr2_+_86333304	36.287	NM_017952	PTCD3	Pentatricopeptide repeat domain 3
chr14_+_77924415	36.236		AHSA1	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr19_+_50180492	36.181		PRMT1	protein arginine methyltransferase 1
chr16_+_3074060	35.857		THOC6	THO complex 6 homolog (Drosophila)
chr22_+_21922026	35.782		UBE2L3	ubiquitin-conjugating enzyme E2L 3
chr16_-_31106125	35.702	NM_024006 NM_206824	VKORC1	vitamin K epoxide reductase complex, subunit 1
chr1_+_19578288	35.532		MRTO4	mRNA turnover 4 homolog (S. cerevisiae)
chr10_+_94352809	35.378	NM_004523	KIF11	kinesin family member 11
chr22_+_24951954	35.351		SNRPD3	small nuclear ribonucleoprotein D3 polypeptide 18kDa
chr17_-_5322870	35.318		NUP88	nucleoporin 88kDa
chr1_+_19578039	35.182	NM_016183	MRTO4	mRNA turnover 4 homolog (S. cerevisiae)
chr22_+_21922004	35.038		UBE2L3	ubiquitin-conjugating enzyme E2L 3
chr11_-_134123138	34.827	NM_001037304 NM_001037305 NM_014174 NM_199297 NM_199298	THYN1	thymocyte nuclear protein 1
chr8_+_145149978	34.759		CYC1	cytochrome c-1
chr4_+_140222668	34.583	NM_057175	NAA15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr10_+_94352873	34.475		KIF11	kinesin family member 11
chr16_+_23690234	34.352		PLK1	polo-like kinase 1
chr14_-_24701472	34.349		NEDD8	neural precursor cell expressed, developmentally down-regulated 8
chr12_-_46662779	34.230		SLC38A1	solute carrier family 38, member 1
chr11_+_61560108	34.039	NM_004111	FEN1	flap structure-specific endonuclease 1
chr7_-_132766834	34.000		CHCHD3	coiled-coil-helix-coiled-coil-helix domain containing 3
chr7_-_132766697	33.953	NM_017812	CHCHD3	coiled-coil-helix-coiled-coil-helix domain containing 3
chr2_-_27593312	33.813	NM_001034116 NM_015636	EIF2B4	eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
chr12_-_2986299	33.731	NM_001243088 NM_001243089 NM_021953 NM_202002 NM_202003	FOXM1	forkhead box M1
chr1_-_186344383	33.689		TPR	translocated promoter region (to activated MET oncogene)
chr19_+_50180408	33.636	NM_001207042 NM_001536 NM_198318	PRMT1	protein arginine methyltransferase 1
chr8_+_145149985	33.620		CYC1	cytochrome c-1
chr11_-_122932806	33.573		HSPA8	heat shock 70kDa protein 8
chr17_+_30771522	33.544		PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr14_-_24701559	33.522		NEDD8	neural precursor cell expressed, developmentally down-regulated 8
chr3_+_127771126	33.064	NM_013336	SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)
chr16_+_3074051	32.895		THOC6	THO complex 6 homolog (Drosophila)
chr18_+_34409058	32.842	NM_020776	KIAA1328	KIAA1328
chr19_-_1095380	32.750	NM_002695	POLR2E	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
chr4_-_174255454	32.539	NM_001130688 NM_002129	HMGB2	high mobility group box 2
chr22_+_24951923	32.271		SNRPD3	small nuclear ribonucleoprotein D3 polypeptide 18kDa
chr1_+_38158189	32.268		CDCA8	cell division cycle associated 8
chr1_-_26232890	32.245	NM_001145454 NM_005563	STMN1	stathmin 1
chr19_+_17378148	32.206	NM_001033549 NM_014173	BABAM1	BRISC and BRCA1 A complex member 1
chr17_+_30771532	32.206		PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr12_-_46662709	32.124		SLC38A1	solute carrier family 38, member 1
chr11_+_67374322	31.971	NM_001166102 NM_007103	NDUFV1	NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
chr12_+_57881735	31.765	NM_004990	MARS	methionyl-tRNA synthetase
chr20_-_524335	31.716	NM_001895 NM_177559 NM_177560	CSNK2A1	casein kinase 2, alpha 1 polypeptide

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.52	1.46e-33	GO:0044237	cellular metabolic process
1.42	5.47e-28	GO:0008152	metabolic process
1.62	7.30e-28	GO:0044260	cellular macromolecule metabolic process
1.84	1.19e-26	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45	1.69e-26	GO:0044238	primary metabolic process
1.73	1.48e-24	GO:0034641	cellular nitrogen compound metabolic process
1.71	2.20e-24	GO:0006807	nitrogen compound metabolic process
1.90	3.71e-23	GO:0090304	nucleic acid metabolic process
1.51	1.32e-22	GO:0043170	macromolecule metabolic process
1.94	1.21e-18	GO:0016070	RNA metabolic process
1.20	3.23e-18	GO:0009987	cellular process
1.68	2.90e-17	GO:0071841	cellular component organization or biogenesis at cellular level
1.86	5.73e-17	GO:0010467	gene expression
2.58	9.24e-15	GO:0000278	mitotic cell cycle
1.65	9.50e-15	GO:0071842	cellular component organization at cellular level
2.61	5.47e-14	GO:0016071	mRNA metabolic process
1.84	6.71e-14	GO:0006996	organelle organization
1.52	1.58e-13	GO:0071840	cellular component organization or biogenesis
3.74	1.74e-13	GO:0000375	RNA splicing, via transesterification reactions
2.41	3.77e-13	GO:0006396	RNA processing
3.09	1.87e-12	GO:0008380	RNA splicing
3.61	6.14e-12	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
3.61	6.14e-12	GO:0000398	nuclear mRNA splicing, via spliceosome
2.72	6.98e-12	GO:0016032	viral reproduction
3.47	9.53e-12	GO:0000075	cell cycle checkpoint
2.28	1.08e-11	GO:0022403	cell cycle phase
3.41	1.14e-11	GO:0071156	regulation of cell cycle arrest
2.01	1.23e-11	GO:0007049	cell cycle
2.15	2.06e-11	GO:0022402	cell cycle process
2.85	2.41e-11	GO:0010564	regulation of cell cycle process
1.49	2.44e-11	GO:0016043	cellular component organization
3.48	1.04e-10	GO:0022613	ribonucleoprotein complex biogenesis
1.57	1.23e-10	GO:0044267	cellular protein metabolic process
1.73	1.73e-10	GO:0034645	cellular macromolecule biosynthetic process
2.46	2.24e-10	GO:0034621	cellular macromolecular complex subunit organization
1.58	3.04e-10	GO:0044249	cellular biosynthetic process
2.65	3.62e-10	GO:0006397	mRNA processing
1.71	5.24e-10	GO:0009059	macromolecule biosynthetic process
3.31	7.95e-10	GO:0071843	cellular component biogenesis at cellular level
1.86	1.46e-09	GO:0044248	cellular catabolic process
2.22	1.65e-09	GO:0051726	regulation of cell cycle
2.91	4.89e-09	GO:0007346	regulation of mitotic cell cycle
1.53	6.13e-09	GO:0009058	biosynthetic process
2.72	2.93e-08	GO:0051329	interphase of mitotic cell cycle
2.67	5.95e-08	GO:0051325	interphase
2.66	6.84e-08	GO:0006412	translation
1.95	8.11e-08	GO:0043933	macromolecular complex subunit organization
1.45	8.53e-08	GO:0019538	protein metabolic process
3.65	1.95e-07	GO:0007093	mitotic cell cycle checkpoint
1.73	8.64e-07	GO:0044085	cellular component biogenesis
2.14	1.18e-06	GO:0044265	cellular macromolecule catabolic process
4.12	1.47e-06	GO:0071826	ribonucleoprotein complex subunit organization
4.19	2.09e-06	GO:0022618	ribonucleoprotein complex assembly
1.63	2.51e-06	GO:0009056	catabolic process
1.68	3.25e-06	GO:0051641	cellular localization
1.85	1.28e-05	GO:0046907	intracellular transport
2.16	2.05e-05	GO:0000279	M phase
2.42	2.33e-05	GO:0000087	M phase of mitotic cell cycle
2.41	2.62e-05	GO:0048285	organelle fission
3.99	2.87e-05	GO:0000216	M/G1 transition of mitotic cell cycle
6.01	3.77e-05	GO:0000245	spliceosome assembly
3.25	4.83e-05	GO:0045333	cellular respiration
3.41	5.37e-05	GO:0000084	S phase of mitotic cell cycle
1.92	6.65e-05	GO:0009057	macromolecule catabolic process
3.06	6.89e-05	GO:0000082	G1/S transition of mitotic cell cycle
2.39	7.24e-05	GO:0000280	nuclear division
2.39	7.24e-05	GO:0007067	mitosis
2.23	7.42e-05	GO:0034622	cellular macromolecular complex assembly
3.35	8.05e-05	GO:0051320	S phase
2.75	8.54e-05	GO:0022411	cellular component disassembly
2.75	8.54e-05	GO:0071845	cellular component disassembly at cellular level
2.37	9.10e-05	GO:0006366	transcription from RNA polymerase II promoter
4.05	1.03e-04	GO:0051352	negative regulation of ligase activity
4.05	1.03e-04	GO:0051444	negative regulation of ubiquitin-protein ligase activity
3.26	1.45e-04	GO:0031570	DNA integrity checkpoint
1.58	1.90e-04	GO:0033036	macromolecule localization
2.39	1.98e-04	GO:0034660	ncRNA metabolic process
2.85	2.23e-04	GO:0010498	proteasomal protein catabolic process
2.85	2.23e-04	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
3.72	2.40e-04	GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
4.01	2.53e-04	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.83	2.60e-04	GO:0031400	negative regulation of protein modification process
1.67	4.54e-04	GO:0032774	RNA biosynthetic process
1.63	4.63e-04	GO:0008104	protein localization
3.46	4.74e-04	GO:0051438	regulation of ubiquitin-protein ligase activity
2.20	4.79e-04	GO:0051603	proteolysis involved in cellular protein catabolic process
1.61	5.27e-04	GO:0051649	establishment of localization in cell
2.21	5.47e-04	GO:0019941	modification-dependent protein catabolic process
3.68	5.79e-04	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.76	6.45e-04	GO:0071844	cellular component assembly at cellular level
2.20	6.68e-04	GO:0043632	modification-dependent macromolecule catabolic process
2.16	8.59e-04	GO:0044257	cellular protein catabolic process
1.85	1.03e-03	GO:0006259	DNA metabolic process
3.31	1.07e-03	GO:0051340	regulation of ligase activity
3.42	1.12e-03	GO:0031397	negative regulation of protein ubiquitination
1.61	1.22e-03	GO:0022607	cellular component assembly
1.76	1.31e-03	GO:0065003	macromolecular complex assembly
2.16	1.91e-03	GO:0006511	ubiquitin-dependent protein catabolic process
1.80	2.28e-03	GO:0051276	chromosome organization
3.07	2.47e-03	GO:0000077	DNA damage checkpoint
2.90	2.65e-03	GO:0006403	RNA localization
3.04	2.94e-03	GO:0032984	macromolecular complex disassembly
3.04	2.94e-03	GO:0034623	cellular macromolecular complex disassembly
3.23	2.99e-03	GO:0022904	respiratory electron transport chain
3.45	3.33e-03	GO:0051443	positive regulation of ubiquitin-protein ligase activity
3.59	3.34e-03	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.02	3.49e-03	GO:0051028	mRNA transport
2.45	3.49e-03	GO:0006457	protein folding
1.86	3.59e-03	GO:0006974	response to DNA damage stimulus
1.79	4.58e-03	GO:0071822	protein complex subunit organization
2.88	4.96e-03	GO:0050657	nucleic acid transport
2.88	4.96e-03	GO:0050658	RNA transport
2.88	4.96e-03	GO:0051236	establishment of RNA localization
3.32	6.12e-03	GO:0007088	regulation of mitosis
3.32	6.12e-03	GO:0051783	regulation of nuclear division
2.02	6.17e-03	GO:0030163	protein catabolic process
3.28	7.44e-03	GO:0051351	positive regulation of ligase activity
2.97	7.76e-03	GO:0090068	positive regulation of cell cycle process
3.71	7.81e-03	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
3.71	7.81e-03	GO:0072395	signal transduction involved in cell cycle checkpoint
3.71	7.81e-03	GO:0072401	signal transduction involved in DNA integrity checkpoint
3.71	7.81e-03	GO:0072404	signal transduction involved in G1/S transition checkpoint
3.71	7.81e-03	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint
3.71	7.81e-03	GO:0072422	signal transduction involved in DNA damage checkpoint
3.71	7.81e-03	GO:0072431	signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
3.71	7.81e-03	GO:0072474	signal transduction involved in mitotic cell cycle G1/S checkpoint
1.62	8.32e-03	GO:0045184	establishment of protein localization
3.24	9.01e-03	GO:0019080	viral genome expression
3.24	9.01e-03	GO:0019083	viral transcription
3.86	9.26e-03	GO:0046782	regulation of viral transcription
3.65	9.84e-03	GO:0048524	positive regulation of viral reproduction
4.05	1.06e-02	GO:0006119	oxidative phosphorylation
2.43	1.21e-02	GO:0006260	DNA replication
2.88	1.26e-02	GO:0031398	positive regulation of protein ubiquitination
1.61	1.28e-02	GO:0015031	protein transport
2.61	1.29e-02	GO:0031396	regulation of protein ubiquitination
4.18	1.53e-02	GO:0042773	ATP synthesis coupled electron transport
4.18	1.53e-02	GO:0042775	mitochondrial ATP synthesis coupled electron transport
3.54	1.54e-02	GO:0006367	transcription initiation from RNA polymerase II promoter
3.54	1.54e-02	GO:0071158	positive regulation of cell cycle arrest
2.98	1.97e-02	GO:0043241	protein complex disassembly
2.98	1.97e-02	GO:0043624	cellular protein complex disassembly
3.06	2.24e-02	GO:0006364	rRNA processing
2.58	2.35e-02	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
1.91	2.59e-02	GO:0032270	positive regulation of cellular protein metabolic process
2.69	2.62e-02	GO:0042254	ribosome biogenesis
2.33	2.69e-02	GO:0034470	ncRNA processing
2.03	2.75e-02	GO:0031401	positive regulation of protein modification process
2.50	2.82e-02	GO:0000226	microtubule cytoskeleton organization
1.94	2.84e-02	GO:0016568	chromatin modification
3.54	2.96e-02	GO:0006368	transcription elongation from RNA polymerase II promoter
2.99	3.15e-02	GO:0006352	transcription initiation, DNA-dependent
3.33	3.53e-02	GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint
3.07	3.56e-02	GO:0000236	mitotic prometaphase
2.57	3.72e-02	GO:0048193	Golgi vesicle transport
1.58	4.45e-02	GO:0033554	cellular response to stress

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.33	2.60e-58	GO:0044424	intracellular part
1.30	1.86e-55	GO:0005622	intracellular
1.40	1.01e-41	GO:0043227	membrane-bounded organelle
1.35	1.31e-41	GO:0043226	organelle
1.35	3.11e-41	GO:0043229	intracellular organelle
1.39	7.99e-41	GO:0043231	intracellular membrane-bounded organelle
1.41	6.30e-40	GO:0005737	cytoplasm
1.52	1.32e-33	GO:0044444	cytoplasmic part
1.54	1.31e-32	GO:0044422	organelle part
1.54	1.42e-32	GO:0044446	intracellular organelle part
1.96	1.35e-27	GO:0044428	nuclear part
1.69	5.78e-27	GO:0032991	macromolecular complex
1.89	3.89e-25	GO:0070013	intracellular organelle lumen
1.87	1.06e-24	GO:0031974	membrane-enclosed lumen
1.86	1.04e-23	GO:0043233	organelle lumen
3.01	3.56e-22	GO:0030529	ribonucleoprotein complex
1.92	8.02e-21	GO:0031981	nuclear lumen
1.42	1.81e-19	GO:0005634	nucleus
1.80	1.58e-18	GO:0005829	cytosol
1.97	7.90e-16	GO:0005654	nucleoplasm
1.88	3.13e-13	GO:0005739	mitochondrion
1.53	1.09e-12	GO:0043234	protein complex
1.56	1.39e-12	GO:0043228	non-membrane-bounded organelle
1.56	1.39e-12	GO:0043232	intracellular non-membrane-bounded organelle
1.08	6.44e-12	GO:0044464	cell part
1.08	6.73e-12	GO:0005623	cell
2.16	3.90e-11	GO:0031967	organelle envelope
2.12	1.22e-10	GO:0031975	envelope
3.70	3.65e-09	GO:0005681	spliceosomal complex
2.00	7.99e-08	GO:0044429	mitochondrial part
4.12	1.40e-06	GO:0071013	catalytic step 2 spliceosome
3.06	1.42e-05	GO:0000793	condensed chromosome
1.85	1.86e-05	GO:0015630	microtubule cytoskeleton
2.03	3.01e-05	GO:0005740	mitochondrial envelope
2.05	3.16e-05	GO:0031966	mitochondrial membrane
1.96	5.89e-05	GO:0005730	nucleolus
2.65	7.52e-05	GO:0005840	ribosome
3.90	8.70e-05	GO:0005643	nuclear pore
1.89	8.97e-05	GO:0005694	chromosome
3.68	1.19e-04	GO:0000779	condensed chromosome, centromeric region
3.74	1.81e-04	GO:0000777	condensed chromosome kinetochore
2.35	2.44e-04	GO:0005635	nuclear envelope
2.95	3.95e-04	GO:0044455	mitochondrial membrane part
3.41	4.39e-04	GO:0046930	pore complex
2.09	4.47e-04	GO:0019866	organelle inner membrane
2.53	4.77e-04	GO:0005819	spindle
2.14	5.23e-04	GO:0005743	mitochondrial inner membrane
1.37	1.17e-03	GO:0031090	organelle membrane
3.22	1.17e-03	GO:0000776	kinetochore
2.61	1.21e-03	GO:0044445	cytosolic part
5.66	1.70e-03	GO:0044452	nucleolar part
3.60	2.54e-03	GO:0000502	proteasome complex
3.43	4.84e-03	GO:0070469	respiratory chain
1.97	4.99e-03	GO:0005815	microtubule organizing center
3.25	5.60e-03	GO:0022626	cytosolic ribosome
2.20	5.67e-03	GO:0005813	centrosome
3.74	5.94e-03	GO:0015935	small ribosomal subunit
1.81	5.99e-03	GO:0044427	chromosomal part
1.63	6.47e-03	GO:0044451	nucleoplasm part
2.10	7.23e-03	GO:0005759	mitochondrial matrix
2.49	9.16e-03	GO:0000775	chromosome, centromeric region
2.13	1.41e-02	GO:0016604	nuclear body
7.72	1.91e-02	GO:0005732	small nucleolar ribonucleoprotein complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.41	6.18e-30	GO:0005515	protein binding
1.17	5.82e-17	GO:0005488	binding
2.04	1.80e-10	GO:0003723	RNA binding
1.48	2.11e-07	GO:0000166	nucleotide binding
1.52	1.16e-06	GO:0035639	purine ribonucleoside triphosphate binding
1.50	2.34e-06	GO:0017076	purine nucleotide binding
1.50	2.52e-06	GO:0032553	ribonucleotide binding
1.50	2.52e-06	GO:0032555	purine ribonucleotide binding
3.08	5.17e-06	GO:0003735	structural constituent of ribosome
1.52	5.65e-05	GO:0005524	ATP binding
1.50	8.90e-05	GO:0032559	adenyl ribonucleotide binding
1.50	1.26e-04	GO:0030554	adenyl nucleotide binding
2.88	2.11e-03	GO:0051082	unfolded protein binding
1.64	2.39e-03	GO:0016462	pyrophosphatase activity
1.63	2.81e-03	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.20	3.26e-03	GO:0003824	catalytic activity
1.63	3.29e-03	GO:0016817	hydrolase activity, acting on acid anhydrides
1.27	3.83e-03	GO:0003676	nucleic acid binding
9.44	5.10e-03	GO:0008139	nuclear localization sequence binding
5.79	5.48e-03	GO:0005048	signal sequence binding
1.62	5.99e-03	GO:0017111	nucleoside-triphosphatase activity
14.16	1.46e-02	GO:0030911	TPR domain binding
3.95	1.74e-02	GO:0016655	oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor