• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: ZNF148.p2

Z-value: 2.128

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_-_31704070	27.174		CLIC1	chloride intracellular channel 1
chr2_-_10588273	25.521		ODC1	ornithine decarboxylase 1
chr6_-_31704093	25.509		CLIC1	chloride intracellular channel 1
chr20_+_3776905	24.544		CDC25B	cell division cycle 25 homolog B (S. pombe)
chr1_+_26606443	24.487		SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3
chr4_-_2936458	23.200		MFSD10	major facilitator superfamily domain containing 10
chr1_+_26606586	22.622		SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3
chr1_+_26606580	21.793		SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3
chrX_-_153599719	21.648		FLNA	filamin A, alpha
chr2_-_10588451	21.288	NM_002539	ODC1	ornithine decarboxylase 1
chr1_+_26606621	21.152		SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3
chr19_+_35645640	20.789	NM_144779 NM_001164605	FXYD5	FXYD domain containing ion transport regulator 5
chr19_+_35645614	20.311	NM_014164	FXYD5	FXYD domain containing ion transport regulator 5
chr4_-_2935851	19.916	NM_001120	MFSD10	major facilitator superfamily domain containing 10
chr4_-_2936563	19.894	NM_001146069	MFSD10	major facilitator superfamily domain containing 10
chr11_-_64014407	19.743	NM_138689	PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr11_-_64014381	19.604		PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chrX_-_153599581	19.601		FLNA	filamin A, alpha
chr11_-_64014264	18.834		PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr6_+_32821924	18.456	NM_002800	PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
chr19_+_35646006	17.996		FXYD5	FXYD domain containing ion transport regulator 5
chrX_-_152989822	17.046	NM_005745	BCAP31	B-cell receptor-associated protein 31
chr22_-_36925212	16.630		EIF3D	eukaryotic translation initiation factor 3, subunit D
chr22_-_36783851	16.598		MYH9	myosin, heavy chain 9, non-muscle
chrX_-_153602998	16.503	NM_001110556 NM_001456	FLNA	filamin A, alpha
chr19_-_2038937	16.258		MKNK2	MAP kinase interacting serine/threonine kinase 2
chr4_-_2935650	16.096		MFSD10	major facilitator superfamily domain containing 10
chrX_-_152989851	16.024		BCAP31	B-cell receptor-associated protein 31
chr3_-_185542807	15.864	NM_001007225 NM_006548	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr22_-_36925270	15.697	NM_003753	EIF3D	eukaryotic translation initiation factor 3, subunit D
chr19_-_41859830	15.696	NM_000660	TGFB1	transforming growth factor, beta 1
chr6_-_32821592	15.692		TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr22_-_36925138	15.273		EIF3D	eukaryotic translation initiation factor 3, subunit D
chr19_-_2046229	15.150		MKNK2	MAP kinase interacting serine/threonine kinase 2
chr18_+_12308236	14.683		TUBB6	tubulin, beta 6 class V
chr22_-_36783977	14.635		MYH9	myosin, heavy chain 9, non-muscle
chr2_+_85132762	14.623	NM_021103	TMSB10	thymosin beta 10
chr2_+_181845605	14.434		UBE2E3	ubiquitin-conjugating enzyme E2E 3
chr6_-_31704281	14.417		CLIC1	chloride intracellular channel 1
chr6_-_32821743	14.256	NM_000593	TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr6_-_31704318	14.168	NM_001288	CLIC1	chloride intracellular channel 1
chr6_-_31704287	14.066		CLIC1	chloride intracellular channel 1
chr7_+_98972351	14.012		ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa
chr6_-_31704272	13.913		CLIC1	chloride intracellular channel 1
chr19_+_50180408	13.864	NM_001207042 NM_001536 NM_198318	PRMT1	protein arginine methyltransferase 1
chr11_+_844062	13.766	NM_001025234	TSPAN4	tetraspanin 4
chr12_-_122231554	13.529	NM_019034	RHOF	ras homolog gene family, member F (in filopodia)
chr2_-_85637473	13.505		CAPG	capping protein (actin filament), gelsolin-like
chr22_-_36925175	13.313		EIF3D	eukaryotic translation initiation factor 3, subunit D
chr13_+_28196029	13.312		POLR1D	polymerase (RNA) I polypeptide D, 16kDa
chr13_+_28196004	13.291		POLR1D	polymerase (RNA) I polypeptide D, 16kDa
chr3_+_49711434	13.063	NM_001640	APEH	N-acylaminoacyl-peptide hydrolase
chr13_+_28196024	13.004		POLR1D	polymerase (RNA) I polypeptide D, 16kDa
chrX_-_152989807	12.980
chr3_-_185542744	12.880		IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr22_-_36784001	12.767		MYH9	myosin, heavy chain 9, non-muscle
chr22_-_36784055	12.576	NM_002473	MYH9	myosin, heavy chain 9, non-muscle
chr11_-_46142955	12.563	NM_001101802 NM_016621	PHF21A	PHD finger protein 21A
chr19_+_50180492	12.526		PRMT1	protein arginine methyltransferase 1
chr11_+_64948685	12.494	NM_001198868	CAPN1	calpain 1, (mu/I) large subunit
chr19_+_48828820	12.477		EMP3	epithelial membrane protein 3
chr12_+_53342842	12.410	NM_000224	KRT18	keratin 18
chr18_+_12308242	12.342	NM_032525	TUBB6	tubulin, beta 6 class V
chr3_-_32544358	12.303	NM_017801	CMTM6	CKLF-like MARVEL transmembrane domain containing 6
chr6_-_4135701	12.036	NM_001166010 NM_006117 NM_206836	ECI2	enoyl-CoA delta isomerase 2
chr2_-_20424627	11.980	NM_002997	SDC1	syndecan 1
chr19_-_41859519	11.914		TGFB1	transforming growth factor, beta 1
chr17_-_62657997	11.828		SMURF2	SMAD specific E3 ubiquitin protein ligase 2
chr12_-_46662779	11.813		SLC38A1	solute carrier family 38, member 1
chr17_-_62658311	11.719	NM_022739	SMURF2	SMAD specific E3 ubiquitin protein ligase 2
chr13_+_28195913	11.612	NM_015972 NM_152705	POLR1D	polymerase (RNA) I polypeptide D, 16kDa
chrX_+_154114609	11.559	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated 2 coagulation factor VIII-associated 3 coagulation factor VIII-associated 1
chr12_-_46662709	11.401		SLC38A1	solute carrier family 38, member 1
chr6_+_34204690	11.373		HMGA1	high mobility group AT-hook 1
chr7_+_98972326	11.331		ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa
chr19_-_41859332	11.283		TGFB1	transforming growth factor, beta 1
chr12_-_109125289	11.160	NM_014325	CORO1C	coronin, actin binding protein, 1C
chr3_+_50273745	11.157		GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr13_-_99229037	11.066		STK24	serine/threonine kinase 24
chr7_-_65447233	10.927	NM_000181	GUSB	glucuronidase, beta
chr12_-_109125275	10.823		CORO1C	coronin, actin binding protein, 1C
chr9_-_113018802	10.816		TXN	thioredoxin
chr1_+_32757707	10.544	NM_004964	HDAC1	histone deacetylase 1
chr15_+_90931470	10.452	NM_003870	IQGAP1	IQ motif containing GTPase activating protein 1
chr1_-_33283632	10.362	NM_003680	YARS	tyrosyl-tRNA synthetase
chr5_-_176900653	10.226	NM_004395	DBN1	drebrin 1
chr5_+_122110778	10.172		SNX2	sorting nexin 2
chr12_-_2986299	10.135	NM_001243088 NM_001243089 NM_021953 NM_202002 NM_202003	FOXM1	forkhead box M1
chr14_-_106092256	10.087		IGHG4	immunoglobulin heavy constant gamma 4 (G4m marker)
chr9_-_113018711	10.061		TXN	thioredoxin
chr1_+_948846	10.004	NM_005101	ISG15	ISG15 ubiquitin-like modifier
chr15_-_60690115	9.962	NM_001002857 NM_001002858 NM_001136015 NM_004039	ANXA2	annexin A2
chrX_-_153602928	9.960		FLNA	filamin A, alpha
chr1_-_8939150	9.918	NM_001428	ENO1	enolase 1, (alpha)
chr16_+_30194730	9.891	NM_001193333 NM_007074	CORO1A	coronin, actin binding protein, 1A
chr3_+_49711751	9.890		APEH	N-acylaminoacyl-peptide hydrolase
chr16_+_30194925	9.880		CORO1A	coronin, actin binding protein, 1A
chr12_-_46662533	9.878		SLC38A1	solute carrier family 38, member 1
chr21_-_40721010	9.774	NM_004965	HMGN1	high mobility group nucleosome binding domain 1
chr2_+_85132999	9.735		TMSB10	thymosin beta 10
chr2_+_181845088	9.709	NM_182678 NM_006357	UBE2E3	ubiquitin-conjugating enzyme E2E 3
chr7_+_26240830	9.699	NM_007276	CBX3	chromobox homolog 3
chr7_-_65447206	9.688		GUSB	glucuronidase, beta
chr2_-_32235603	9.565	NM_001137602 NM_015955	MEMO1	mediator of cell motility 1
chr19_-_50143350	9.438	NM_006270	RRAS	related RAS viral (r-ras) oncogene homolog
chr1_-_94374949	9.391		GCLM	glutamate-cysteine ligase, modifier subunit
chr19_-_14529853	9.380		DDX39A	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr1_+_32757702	9.370		HDAC1	histone deacetylase 1
chr12_+_53342654	9.341	NM_199187	KRT18	keratin 18
chr3_+_49711816	9.317		APEH	N-acylaminoacyl-peptide hydrolase
chr19_-_14530129	9.268		DDX39A	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr2_+_181845368	9.263		UBE2E3	ubiquitin-conjugating enzyme E2E 3
chr8_-_101734313	9.250	NM_002568	PABPC1	poly(A) binding protein, cytoplasmic 1
chr19_-_14530155	9.158	NM_005804	DDX39A	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr6_-_86352982	9.149	NM_001159677 NM_006372	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr16_-_88878316	9.071	NM_000485 NM_001030018	APRT	adenine phosphoribosyltransferase
chr7_+_26241329	9.069		CBX3	chromobox homolog 3
chr6_+_41754419	9.060		TOMM6	translocase of outer mitochondrial membrane 6 homolog (yeast)
chr17_-_47492215	9.052		PHB	prohibitin
chr11_-_64014140	9.038		PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr12_-_109125254	8.986		CORO1C	coronin, actin binding protein, 1C
chr16_+_29817810	8.972	NM_001042539 NM_002383	MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr3_+_184032849	8.935	NM_182917	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr17_+_76164624	8.925	NM_004710	SYNGR2	synaptogyrin 2
chr15_-_91537724	8.923	NM_003981 NM_199413 NM_199414	PRC1	protein regulator of cytokinesis 1
chr1_-_94374986	8.919	NM_002061	GCLM	glutamate-cysteine ligase, modifier subunit
chr6_-_36515245	8.896	NM_007271	STK38	serine/threonine kinase 38
chr14_-_74959976	8.873		NPC2	Niemann-Pick disease, type C2
chr20_+_62371109	8.846	NM_020062	SLC2A4RG	SLC2A4 regulator
chr9_+_110046333	8.791	NM_001244724	RAD23B	RAD23 homolog B (S. cerevisiae)
chr8_-_101734290	8.791		PABPC1	poly(A) binding protein, cytoplasmic 1
chr2_-_61765345	8.746		XPO1	exportin 1 (CRM1 homolog, yeast)
chr14_-_100841926	8.738	NM_004184 NM_213646	WARS	tryptophanyl-tRNA synthetase
chr3_-_52567708	8.636	NM_001134231	NT5DC2	5'-nucleotidase domain containing 2
chr19_-_47217576	8.625	NM_001079882	PRKD2	protein kinase D2
chr5_-_176900591	8.619		DBN1	drebrin 1
chr2_-_61765394	8.595	NM_003400	XPO1	exportin 1 (CRM1 homolog, yeast)
chr5_+_95998678	8.593		CAST	calpastatin
chr7_+_143058794	8.591		ZYX	zyxin
chr8_-_101963353	8.526	NM_001135700 NM_001135701	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr1_-_1822501	8.515		GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1
chr20_+_62371218	8.504		SLC2A4RG	SLC2A4 regulator
chr1_-_43637788	8.485		EBNA1BP2	EBNA1 binding protein 2
chr1_-_23670743	8.446	NM_001102397 NM_001102398 NM_001102399 NM_005826	HNRNPR	heterogeneous nuclear ribonucleoprotein R
chr1_-_153538305	8.386	NM_005978	S100A2	S100 calcium binding protein A2
chr3_-_52567809	8.314		NT5DC2	5'-nucleotidase domain containing 2
chr7_-_65447162	8.301		GUSB	glucuronidase, beta
chr1_+_32757711	8.254		HDAC1	histone deacetylase 1
chr18_+_12948010	8.253		SEH1L	SEH1-like (S. cerevisiae)
chr6_+_34205369	8.169		HMGA1	high mobility group AT-hook 1
chr2_+_85198176	8.164	NM_020122	KCMF1	potassium channel modulatory factor 1
chr14_+_23340955	8.106	NM_014045	LRP10	low density lipoprotein receptor-related protein 10
chr19_+_54695103	8.093	NM_001077446	TSEN34	tRNA splicing endonuclease 34 homolog (S. cerevisiae)
chr7_+_17338182	8.092	NM_001621	AHR	aryl hydrocarbon receptor
chr1_+_87170515	8.090		SH3GLB1	SH3-domain GRB2-like endophilin B1
chr9_+_110045516	8.073	NM_002874	RAD23B	RAD23 homolog B (S. cerevisiae)
chr19_-_50432952	8.061	NM_016553	NUP62	nucleoporin 62kDa
chr3_-_184870727	8.061	NM_001025266	C3orf70	chromosome 3 open reading frame 70
chr3_+_128997713	7.993	NM_001006109	C3orf37	chromosome 3 open reading frame 37
chr1_+_10459084	7.984	NM_002631	PGD	phosphogluconate dehydrogenase
chr6_-_31704304	7.982		CLIC1	chloride intracellular channel 1
chr6_+_30689414	7.905		TUBB	tubulin, beta class I
chr1_-_33282844	7.835		YARS	tyrosyl-tRNA synthetase
chr1_-_1822493	7.799		GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1
chr11_-_67169252	7.649		PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme
chr18_+_29078026	7.642	NM_001943	DSG2	desmoglein 2
chrX_+_64887534	7.642		MSN	moesin
chr19_+_10982244	7.638	NM_199141	CARM1	coactivator-associated arginine methyltransferase 1
chr12_+_56522202	7.632		ESYT1	extended synaptotagmin-like protein 1
chr1_+_44440642	7.608		ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr6_-_159065739	7.580	NM_006519	DYNLT1	dynein, light chain, Tctex-type 1
chr11_-_64545864	7.552		SF1	splicing factor 1
chr17_-_5342380	7.546		C1QBP	complement component 1, q subcomponent binding protein
chr8_+_26149080	7.507		PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr7_-_65447187	7.452		GUSB	glucuronidase, beta
chr17_-_5342424	7.435	NM_001212	C1QBP	complement component 1, q subcomponent binding protein
chr10_+_70883856	7.426	NM_001035260 NM_004896	VPS26A	vacuolar protein sorting 26 homolog A (S. pombe)
chr18_+_11981421	7.420	NM_014214	IMPA2	inositol(myo)-1(or 4)-monophosphatase 2
chr20_+_32581553	7.343		RALY	RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr9_+_110045551	7.333		RAD23B	RAD23 homolog B (S. cerevisiae)
chr12_-_2986095	7.330		FOXM1	forkhead box M1
chr19_+_797452	7.272		PTBP1	polypyrimidine tract binding protein 1
chr3_-_12705626	7.263	NM_002880	RAF1	v-raf-1 murine leukemia viral oncogene homolog 1
chr7_-_55640198	7.258	NM_030796	VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1
chr9_+_140149768	7.235		COBRA1	cofactor of BRCA1
chr1_-_1822432	7.206		GNB1 CDK11B	guanine nucleotide binding protein (G protein), beta polypeptide 1 cyclin-dependent kinase 11B
chr10_-_126849066	7.130	NM_001329	CTBP2	C-terminal binding protein 2
chr16_+_29831755	7.117		MVP	major vault protein
chr19_+_16187306	7.104		TPM4	tropomyosin 4
chr16_+_128233	7.084		MPG	N-methylpurine-DNA glycosylase
chr3_+_128997616	7.072	NM_020187	C3orf37	chromosome 3 open reading frame 37
chr10_-_126849010	7.059		CTBP2	C-terminal binding protein 2
chr2_-_61765367	7.039		XPO1	exportin 1 (CRM1 homolog, yeast)
chr7_+_26241281	6.960	NM_016587	CBX3	chromobox homolog 3
chr12_+_64798050	6.908	NM_007235	XPOT	exportin, tRNA (nuclear export receptor for tRNAs)
chr8_-_101734162	6.883		PABPC1	poly(A) binding protein, cytoplasmic 1
chr21_+_34775189	6.883	NM_005534	IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)
chr9_+_140149756	6.875	NM_015456	COBRA1	cofactor of BRCA1
chr12_+_104324214	6.839		HSP90B1	heat shock protein 90kDa beta (Grp94), member 1
chr1_-_94375028	6.832		GCLM	glutamate-cysteine ligase, modifier subunit

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.22	2.76e-55	GO:0009987	cellular process
1.38	1.25e-43	GO:0044237	cellular metabolic process
1.32	2.12e-38	GO:0008152	metabolic process
1.35	3.73e-37	GO:0044238	primary metabolic process
1.44	2.06e-34	GO:0044260	cellular macromolecule metabolic process
1.39	5.95e-32	GO:0043170	macromolecule metabolic process
1.26	3.39e-26	GO:0050789	regulation of biological process
1.24	4.12e-25	GO:0065007	biological regulation
1.26	5.39e-24	GO:0050794	regulation of cellular process
1.53	1.90e-23	GO:0044267	cellular protein metabolic process
1.43	4.04e-23	GO:0071840	cellular component organization or biogenesis
1.44	6.07e-23	GO:0016043	cellular component organization
1.47	4.72e-21	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.52	1.18e-20	GO:0048519	negative regulation of biological process
1.47	2.80e-20	GO:0071841	cellular component organization or biogenesis at cellular level
1.36	3.10e-20	GO:0051716	cellular response to stimulus
1.48	7.08e-20	GO:0071842	cellular component organization at cellular level
1.54	7.29e-20	GO:0048523	negative regulation of cellular process
1.41	1.95e-19	GO:0006807	nitrogen compound metabolic process
1.46	2.10e-19	GO:0048518	positive regulation of biological process
1.43	5.01e-19	GO:0019538	protein metabolic process
1.48	2.11e-18	GO:0006950	response to stress
1.48	2.31e-18	GO:0048522	positive regulation of cellular process
1.40	2.18e-17	GO:0034641	cellular nitrogen compound metabolic process
1.59	7.72e-17	GO:0006996	organelle organization
1.37	1.42e-16	GO:0007165	signal transduction
1.65	2.97e-15	GO:0002376	immune system process
1.51	2.20e-14	GO:0006464	protein modification process
2.23	4.37e-14	GO:0044419	interspecies interaction between organisms
1.48	7.55e-14	GO:0043412	macromolecule modification
1.31	8.29e-14	GO:0019222	regulation of metabolic process
1.41	8.47e-14	GO:0009058	biosynthetic process
1.42	8.83e-14	GO:0044249	cellular biosynthetic process
1.22	1.05e-13	GO:0050896	response to stimulus
1.31	5.63e-13	GO:0023052	signaling
1.43	7.11e-13	GO:0090304	nucleic acid metabolic process
1.33	7.33e-13	GO:0060255	regulation of macromolecule metabolic process
1.42	1.48e-12	GO:0042221	response to chemical stimulus
1.77	1.48e-12	GO:0046907	intracellular transport
1.66	1.52e-12	GO:0032268	regulation of cellular protein metabolic process
1.64	1.81e-12	GO:0051246	regulation of protein metabolic process
1.31	1.29e-11	GO:0031323	regulation of cellular metabolic process
1.31	2.50e-11	GO:0080090	regulation of primary metabolic process
1.47	5.09e-11	GO:0009059	macromolecule biosynthetic process
1.55	7.65e-11	GO:0010033	response to organic substance
1.54	8.67e-11	GO:0033036	macromolecule localization
1.54	1.54e-10	GO:0051641	cellular localization
1.46	2.16e-10	GO:0034645	cellular macromolecule biosynthetic process
1.43	2.30e-10	GO:0048583	regulation of response to stimulus
1.55	4.22e-10	GO:0031325	positive regulation of cellular metabolic process
1.53	6.59e-10	GO:0009893	positive regulation of metabolic process
1.55	7.35e-10	GO:0044248	cellular catabolic process
1.59	1.31e-09	GO:0007049	cell cycle
1.55	1.71e-09	GO:0010604	positive regulation of macromolecule metabolic process
1.54	2.27e-09	GO:0044085	cellular component biogenesis
1.48	2.32e-09	GO:0009056	catabolic process
1.65	3.15e-09	GO:0051128	regulation of cellular component organization
1.55	4.61e-09	GO:0051649	establishment of localization in cell
1.75	4.62e-09	GO:0051726	regulation of cell cycle
1.61	6.65e-09	GO:0051704	multi-organism process
1.64	6.67e-09	GO:0033554	cellular response to stress
1.55	1.07e-08	GO:0022607	cellular component assembly
1.57	1.14e-08	GO:0009892	negative regulation of metabolic process
1.46	1.88e-08	GO:0009966	regulation of signal transduction
1.40	2.39e-08	GO:0010467	gene expression
1.59	2.78e-08	GO:0010605	negative regulation of macromolecule metabolic process
1.54	3.05e-08	GO:0008104	protein localization
1.59	3.31e-08	GO:0031324	negative regulation of cellular metabolic process
1.74	4.06e-08	GO:0071822	protein complex subunit organization
1.73	6.28e-08	GO:0042060	wound healing
1.55	1.01e-07	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.52	1.14e-07	GO:0010941	regulation of cell death
1.53	1.28e-07	GO:0043067	regulation of programmed cell death
1.25	1.42e-07	GO:0032502	developmental process
1.52	1.70e-07	GO:0042981	regulation of apoptosis
1.67	3.17e-07	GO:0007167	enzyme linked receptor protein signaling pathway
1.74	4.01e-07	GO:0044265	cellular macromolecule catabolic process
1.61	4.27e-07	GO:0016192	vesicle-mediated transport
1.64	4.68e-07	GO:0002682	regulation of immune system process
1.68	5.05e-07	GO:0009057	macromolecule catabolic process
1.58	5.40e-07	GO:0022402	cell cycle process
1.38	5.81e-07	GO:0016070	RNA metabolic process
1.70	6.12e-07	GO:0000278	mitotic cell cycle
2.02	1.02e-06	GO:0010608	posttranscriptional regulation of gene expression
1.74	1.26e-06	GO:0006753	nucleoside phosphate metabolic process
1.74	1.26e-06	GO:0009117	nucleotide metabolic process
1.39	1.40e-06	GO:0023051	regulation of signaling
1.75	1.43e-06	GO:0007010	cytoskeleton organization
1.74	1.66e-06	GO:0070271	protein complex biogenesis
1.33	1.67e-06	GO:0065008	regulation of biological quality
1.56	1.70e-06	GO:0043933	macromolecular complex subunit organization
1.74	1.92e-06	GO:0007596	blood coagulation
1.74	1.92e-06	GO:0050817	coagulation
1.53	2.54e-06	GO:0009611	response to wounding
1.56	2.75e-06	GO:0031399	regulation of protein modification process
1.73	2.98e-06	GO:0007599	hemostasis
1.29	3.97e-06	GO:0010468	regulation of gene expression
1.58	4.54e-06	GO:0071844	cellular component assembly at cellular level
1.72	4.56e-06	GO:0006461	protein complex assembly
1.67	4.84e-06	GO:0050878	regulation of body fluid levels
1.80	5.29e-06	GO:0051247	positive regulation of protein metabolic process
1.67	6.45e-06	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
1.75	6.86e-06	GO:0060548	negative regulation of cell death
1.56	7.99e-06	GO:0006955	immune response
1.48	1.12e-05	GO:0006793	phosphorus metabolic process
1.48	1.12e-05	GO:0006796	phosphate metabolic process
1.25	1.21e-05	GO:0048856	anatomical structure development
1.49	1.26e-05	GO:0070887	cellular response to chemical stimulus
1.79	1.69e-05	GO:0032270	positive regulation of cellular protein metabolic process
1.51	2.05e-05	GO:0045184	establishment of protein localization
1.99	2.14e-05	GO:0030036	actin cytoskeleton organization
1.37	2.46e-05	GO:0009653	anatomical structure morphogenesis
1.50	2.88e-05	GO:0008219	cell death
1.47	3.04e-05	GO:0042127	regulation of cell proliferation
1.49	4.28e-05	GO:0016265	death
1.50	4.38e-05	GO:0015031	protein transport
1.83	4.69e-05	GO:0009259	ribonucleotide metabolic process
1.37	4.90e-05	GO:0065009	regulation of molecular function
1.44	5.53e-05	GO:0010646	regulation of cell communication
1.28	6.66e-05	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.56	6.74e-05	GO:0022403	cell cycle phase
1.33	6.91e-05	GO:0007166	cell surface receptor linked signaling pathway
2.19	7.63e-05	GO:0022415	viral reproductive process
1.22	7.82e-05	GO:0051179	localization
1.38	8.50e-05	GO:0035556	intracellular signal transduction
2.12	8.61e-05	GO:0051169	nuclear transport
1.22	8.69e-05	GO:0007275	multicellular organismal development
1.70	8.92e-05	GO:0043069	negative regulation of programmed cell death
1.69	1.01e-04	GO:0008283	cell proliferation
1.70	1.03e-04	GO:0043066	negative regulation of apoptosis
1.70	1.03e-04	GO:0072521	purine-containing compound metabolic process
1.57	1.08e-04	GO:0071310	cellular response to organic substance
1.86	1.11e-04	GO:0030029	actin filament-based process
1.49	1.29e-04	GO:0031328	positive regulation of cellular biosynthetic process
1.50	1.30e-04	GO:0048584	positive regulation of response to stimulus
1.73	1.36e-04	GO:0006163	purine nucleotide metabolic process
2.10	1.49e-04	GO:0006913	nucleocytoplasmic transport
1.57	1.56e-04	GO:0051172	negative regulation of nitrogen compound metabolic process
1.32	1.72e-04	GO:0044281	small molecule metabolic process
1.80	1.81e-04	GO:0009150	purine ribonucleotide metabolic process
1.76	2.01e-04	GO:0051301	cell division
1.58	2.02e-04	GO:0006259	DNA metabolic process
1.52	2.02e-04	GO:0012501	programmed cell death
2.21	2.17e-04	GO:0034330	cell junction organization
1.48	2.24e-04	GO:0044093	positive regulation of molecular function
1.53	2.27e-04	GO:0019220	regulation of phosphate metabolic process
1.53	2.27e-04	GO:0051174	regulation of phosphorus metabolic process
1.82	2.32e-04	GO:0009141	nucleoside triphosphate metabolic process
1.57	2.32e-04	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.49	2.98e-04	GO:0051173	positive regulation of nitrogen compound metabolic process
1.61	3.13e-04	GO:0070727	cellular macromolecule localization
1.69	3.15e-04	GO:0016032	viral reproduction
1.62	3.20e-04	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.26	3.26e-04	GO:0010556	regulation of macromolecule biosynthetic process
1.24	3.55e-04	GO:0051171	regulation of nitrogen compound metabolic process
1.96	3.60e-04	GO:0045786	negative regulation of cell cycle
1.73	3.66e-04	GO:0016568	chromatin modification
1.94	3.86e-04	GO:0048011	nerve growth factor receptor signaling pathway
1.65	3.88e-04	GO:0050776	regulation of immune response
1.77	3.97e-04	GO:0033043	regulation of organelle organization
1.77	3.97e-04	GO:0051098	regulation of binding
1.61	4.08e-04	GO:0034613	cellular protein localization
1.75	4.16e-04	GO:0018193	peptidyl-amino acid modification
1.46	4.40e-04	GO:0009891	positive regulation of biosynthetic process
1.24	4.69e-04	GO:0031326	regulation of cellular biosynthetic process
2.24	4.76e-04	GO:0034329	cell junction assembly
2.02	4.85e-04	GO:0022411	cellular component disassembly
2.02	4.85e-04	GO:0071845	cellular component disassembly at cellular level
1.79	5.04e-04	GO:0008380	RNA splicing
1.24	5.45e-04	GO:0009889	regulation of biosynthetic process
1.80	5.65e-04	GO:0009199	ribonucleoside triphosphate metabolic process
1.50	6.45e-04	GO:0006915	apoptosis
1.54	7.16e-04	GO:0051276	chromosome organization
1.74	7.33e-04	GO:0070647	protein modification by small protein conjugation or removal
1.58	7.43e-04	GO:0051253	negative regulation of RNA metabolic process
1.51	7.52e-04	GO:0009890	negative regulation of biosynthetic process
1.79	7.76e-04	GO:0009144	purine nucleoside triphosphate metabolic process
1.49	8.12e-04	GO:0010557	positive regulation of macromolecule biosynthetic process
2.16	8.51e-04	GO:0051052	regulation of DNA metabolic process
1.26	9.28e-04	GO:0051252	regulation of RNA metabolic process
1.51	9.68e-04	GO:0042325	regulation of phosphorylation
1.72	9.89e-04	GO:0010564	regulation of cell cycle process
1.51	1.03e-03	GO:0031327	negative regulation of cellular biosynthetic process
1.79	1.04e-03	GO:0009205	purine ribonucleoside triphosphate metabolic process
2.21	1.09e-03	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
2.22	1.17e-03	GO:0006403	RNA localization
2.63	1.20e-03	GO:0007173	epidermal growth factor receptor signaling pathway
1.51	1.24e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
2.01	1.25e-03	GO:0002757	immune response-activating signal transduction
2.24	1.25e-03	GO:0050657	nucleic acid transport
2.24	1.25e-03	GO:0050658	RNA transport
2.24	1.25e-03	GO:0051236	establishment of RNA localization
1.53	1.35e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.41	1.36e-03	GO:0032774	RNA biosynthetic process
1.49	1.36e-03	GO:0065003	macromolecular complex assembly
1.77	1.44e-03	GO:0051329	interphase of mitotic cell cycle
1.76	1.46e-03	GO:0051325	interphase
1.47	1.51e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.44	1.61e-03	GO:0016310	phosphorylation
2.16	1.62e-03	GO:0019058	viral infectious cycle
1.62	1.63e-03	GO:0002684	positive regulation of immune system process
1.53	1.72e-03	GO:0010629	negative regulation of gene expression
2.05	1.94e-03	GO:0043623	cellular protein complex assembly
1.22	2.00e-03	GO:0048731	system development
1.58	2.11e-03	GO:0009967	positive regulation of signal transduction
1.23	2.17e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.50	2.18e-03	GO:0046483	heterocycle metabolic process
1.71	2.31e-03	GO:0051603	proteolysis involved in cellular protein catabolic process
1.97	2.78e-03	GO:0002764	immune response-regulating signaling pathway
2.06	2.97e-03	GO:0050900	leukocyte migration
1.97	3.13e-03	GO:0016569	covalent chromatin modification
1.55	3.27e-03	GO:0023056	positive regulation of signaling
1.67	3.39e-03	GO:0030163	protein catabolic process
1.81	3.56e-03	GO:0051248	negative regulation of protein metabolic process
1.56	3.70e-03	GO:0043065	positive regulation of apoptosis
1.78	3.79e-03	GO:0007346	regulation of mitotic cell cycle
1.60	3.86e-03	GO:0016044	cellular membrane organization
1.48	3.89e-03	GO:0009719	response to endogenous stimulus
1.35	3.90e-03	GO:0050790	regulation of catalytic activity
1.55	4.19e-03	GO:0010647	positive regulation of cell communication
1.77	4.42e-03	GO:0010740	positive regulation of intracellular protein kinase cascade
2.17	4.64e-03	GO:0043388	positive regulation of DNA binding
1.59	4.87e-03	GO:0061024	membrane organization
2.08	5.03e-03	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
1.56	5.05e-03	GO:0034621	cellular macromolecular complex subunit organization
1.55	5.14e-03	GO:0043068	positive regulation of programmed cell death
1.49	5.15e-03	GO:0001932	regulation of protein phosphorylation
1.68	5.27e-03	GO:0044257	cellular protein catabolic process
1.98	5.42e-03	GO:0030155	regulation of cell adhesion
2.67	5.61e-03	GO:0060333	interferon-gamma-mediated signaling pathway
1.84	5.76e-03	GO:0009261	ribonucleotide catabolic process
1.60	5.90e-03	GO:0032583	regulation of gene-specific transcription
1.69	6.14e-03	GO:0019941	modification-dependent protein catabolic process
1.71	6.18e-03	GO:0031401	positive regulation of protein modification process
1.53	6.21e-03	GO:0016071	mRNA metabolic process
2.06	6.25e-03	GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade
2.06	6.25e-03	GO:0051099	positive regulation of binding
2.17	6.41e-03	GO:0043254	regulation of protein complex assembly
3.01	6.75e-03	GO:0045767	regulation of anti-apoptosis
1.83	6.81e-03	GO:0002253	activation of immune response
1.54	6.87e-03	GO:0010942	positive regulation of cell death
1.63	6.99e-03	GO:0010627	regulation of intracellular protein kinase cascade
1.80	7.38e-03	GO:0032269	negative regulation of cellular protein metabolic process
1.53	7.92e-03	GO:0045892	negative regulation of transcription, DNA-dependent
1.68	8.06e-03	GO:0043632	modification-dependent macromolecule catabolic process
2.57	8.25e-03	GO:0044403	symbiosis, encompassing mutualism through parasitism
1.52	8.75e-03	GO:0006928	cellular component movement
1.97	9.03e-03	GO:0006417	regulation of translation
1.83	9.18e-03	GO:0009154	purine ribonucleotide catabolic process
1.71	9.43e-03	GO:0051130	positive regulation of cellular component organization
2.03	9.55e-03	GO:0007568	aging
1.53	9.75e-03	GO:0006974	response to DNA damage stimulus
1.53	9.75e-03	GO:0080134	regulation of response to stress
1.93	1.04e-02	GO:0016570	histone modification
1.83	1.05e-02	GO:0009203	ribonucleoside triphosphate catabolic process
1.83	1.05e-02	GO:0009207	purine ribonucleoside triphosphate catabolic process
1.48	1.12e-02	GO:0009725	response to hormone stimulus
1.46	1.12e-02	GO:0045595	regulation of cell differentiation
1.59	1.14e-02	GO:0008285	negative regulation of cell proliferation
1.61	1.14e-02	GO:0006886	intracellular protein transport
1.46	1.23e-02	GO:0051254	positive regulation of RNA metabolic process
1.82	1.24e-02	GO:0009146	purine nucleoside triphosphate catabolic process
1.72	1.25e-02	GO:0032446	protein modification by small protein conjugation
1.59	1.38e-02	GO:0009968	negative regulation of signal transduction
1.68	1.42e-02	GO:0006412	translation
1.86	1.51e-02	GO:0044087	regulation of cellular component biogenesis
1.98	1.57e-02	GO:0046039	GTP metabolic process
1.43	1.66e-02	GO:0006468	protein phosphorylation
1.44	1.68e-02	GO:0043085	positive regulation of catalytic activity
1.36	1.72e-02	GO:0009605	response to external stimulus
1.54	1.81e-02	GO:0006325	chromatin organization
3.42	1.84e-02	GO:0043488	regulation of mRNA stability
1.74	1.89e-02	GO:0009166	nucleotide catabolic process
1.56	1.89e-02	GO:0023057	negative regulation of signaling
2.34	1.97e-02	GO:0051168	nuclear export
1.80	2.01e-02	GO:0009143	nucleoside triphosphate catabolic process
1.66	2.10e-02	GO:0006511	ubiquitin-dependent protein catabolic process
2.14	2.14e-02	GO:0016197	endosome transport
1.71	2.53e-02	GO:0051101	regulation of DNA binding
1.46	2.59e-02	GO:0045893	positive regulation of transcription, DNA-dependent
2.72	2.61e-02	GO:0051701	interaction with host
2.21	2.75e-02	GO:0051235	maintenance of location
1.75	2.86e-02	GO:0006195	purine nucleotide catabolic process
1.83	2.86e-02	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.83	2.86e-02	GO:0000398	nuclear mRNA splicing, via spliceosome
1.68	2.86e-02	GO:0042493	response to drug
1.82	2.95e-02	GO:0000375	RNA splicing, via transesterification reactions
1.92	2.98e-02	GO:0031400	negative regulation of protein modification process
2.09	3.07e-02	GO:0007265	Ras protein signal transduction
1.19	3.08e-02	GO:0051234	establishment of localization
3.31	3.16e-02	GO:0043487	regulation of RNA stability
1.37	3.19e-02	GO:0050793	regulation of developmental process
2.16	3.23e-02	GO:0002429	immune response-activating cell surface receptor signaling pathway
1.73	3.33e-02	GO:0072523	purine-containing compound catabolic process
1.67	3.74e-02	GO:0002520	immune system development
1.54	3.74e-02	GO:0010648	negative regulation of cell communication
2.21	3.81e-02	GO:0050851	antigen receptor-mediated signaling pathway
1.87	3.95e-02	GO:0043687	post-translational protein modification
1.23	3.98e-02	GO:0048869	cellular developmental process
1.37	3.98e-02	GO:0006351	transcription, DNA-dependent
2.43	3.99e-02	GO:0071346	cellular response to interferon-gamma
2.54	4.02e-02	GO:0009411	response to UV
2.90	4.06e-02	GO:0007569	cell aging
1.19	4.52e-02	GO:0006810	transport
1.66	4.91e-02	GO:0050778	positive regulation of immune response

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.33	3.47e-58	GO:0005737	cytoplasm
1.22	9.10e-58	GO:0044424	intracellular part
1.20	5.53e-51	GO:0005622	intracellular
1.23	1.67e-42	GO:0043229	intracellular organelle
1.23	3.83e-42	GO:0043226	organelle
1.37	4.42e-40	GO:0044444	cytoplasmic part
1.39	6.41e-40	GO:0044446	intracellular organelle part
1.38	1.48e-39	GO:0044422	organelle part
1.25	1.28e-37	GO:0043231	intracellular membrane-bounded organelle
1.25	1.57e-37	GO:0043227	membrane-bounded organelle
1.70	5.23e-37	GO:0044428	nuclear part
1.71	9.58e-36	GO:0005829	cytosol
1.61	5.20e-31	GO:0031974	membrane-enclosed lumen
1.62	7.11e-31	GO:0043233	organelle lumen
1.62	6.41e-30	GO:0070013	intracellular organelle lumen
1.68	1.32e-28	GO:0031981	nuclear lumen
1.45	1.67e-28	GO:0032991	macromolecular complex
1.30	4.97e-24	GO:0005634	nucleus
1.45	9.99e-23	GO:0043234	protein complex
1.72	3.25e-22	GO:0005654	nucleoplasm
1.40	6.24e-16	GO:0043228	non-membrane-bounded organelle
1.40	6.24e-16	GO:0043232	intracellular non-membrane-bounded organelle
1.06	2.63e-11	GO:0044464	cell part
1.06	2.81e-11	GO:0005623	cell
1.64	1.15e-08	GO:0031967	organelle envelope
1.63	1.42e-08	GO:0031975	envelope
2.14	1.55e-08	GO:0005635	nuclear envelope
1.73	1.26e-07	GO:0005730	nucleolus
1.94	3.43e-07	GO:0015629	actin cytoskeleton
1.56	1.58e-06	GO:0044451	nucleoplasm part
1.30	2.56e-06	GO:0031090	organelle membrane
1.36	2.65e-06	GO:0012505	endomembrane system
1.65	4.48e-06	GO:0030529	ribonucleoprotein complex
2.13	2.00e-05	GO:0070161	anchoring junction
1.33	7.70e-05	GO:0005856	cytoskeleton
2.16	9.44e-05	GO:0031965	nuclear membrane
2.41	1.03e-04	GO:0005925	focal adhesion
2.33	1.27e-04	GO:0030055	cell-substrate junction
2.35	1.32e-04	GO:0005924	cell-substrate adherens junction
2.09	2.14e-04	GO:0005912	adherens junction
4.41	6.67e-04	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
1.38	6.94e-04	GO:0005794	Golgi apparatus
1.36	8.76e-04	GO:0005783	endoplasmic reticulum
1.63	1.89e-03	GO:0048471	perinuclear region of cytoplasm
1.88	2.12e-03	GO:0031252	cell leading edge
1.49	2.39e-03	GO:0005694	chromosome
1.52	4.52e-03	GO:0044427	chromosomal part
1.75	5.78e-03	GO:0016604	nuclear body
2.23	6.29e-03	GO:0042470	melanosome
2.23	6.29e-03	GO:0048770	pigment granule
1.32	6.49e-03	GO:0000267	cell fraction
2.40	8.21e-03	GO:0005643	nuclear pore
1.59	1.05e-02	GO:0005625	soluble fraction
2.23	1.21e-02	GO:0046930	pore complex
1.36	2.51e-02	GO:0044432	endoplasmic reticulum part
1.83	3.75e-02	GO:0045121	membrane raft
1.37	4.48e-02	GO:0015630	microtubule cytoskeleton
1.34	4.88e-02	GO:0031982	vesicle
1.74	4.89e-02	GO:0005819	spindle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.43	2.18e-79	GO:0005515	protein binding
1.17	2.54e-40	GO:0005488	binding
1.66	1.20e-09	GO:0019899	enzyme binding
1.34	4.61e-09	GO:0000166	nucleotide binding
1.63	8.61e-09	GO:0042802	identical protein binding
1.56	1.51e-07	GO:0003723	RNA binding
1.31	1.03e-05	GO:0017076	purine nucleotide binding
1.31	1.70e-05	GO:0035639	purine ribonucleoside triphosphate binding
1.31	2.44e-05	GO:0032553	ribonucleotide binding
1.31	2.44e-05	GO:0032555	purine ribonucleotide binding
1.55	2.54e-05	GO:0046983	protein dimerization activity
1.67	2.99e-05	GO:0019904	protein domain specific binding
2.03	6.75e-05	GO:0003682	chromatin binding
1.15	9.13e-05	GO:0003824	catalytic activity
1.67	3.29e-04	GO:0000988	protein binding transcription factor activity
1.67	3.29e-04	GO:0000989	transcription factor binding transcription factor activity
1.89	5.35e-04	GO:0003924	GTPase activity
1.65	5.62e-04	GO:0003712	transcription cofactor activity
1.30	6.89e-04	GO:0030554	adenyl nucleotide binding
2.05	1.07e-03	GO:0003714	transcription corepressor activity
2.50	1.61e-03	GO:0042393	histone binding
1.71	1.62e-03	GO:0008134	transcription factor binding
1.29	1.76e-03	GO:0032559	adenyl ribonucleotide binding
1.29	1.92e-03	GO:0005524	ATP binding
1.48	1.99e-03	GO:0005198	structural molecule activity
1.57	2.54e-03	GO:0042803	protein homodimerization activity
2.01	2.76e-03	GO:0008022	protein C-terminus binding
1.77	3.62e-03	GO:0019900	kinase binding
1.36	1.11e-02	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.40	1.25e-02	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.38	1.29e-02	GO:0016301	kinase activity
1.77	1.71e-02	GO:0019901	protein kinase binding
1.84	1.99e-02	GO:0000287	magnesium ion binding
2.26	2.22e-02	GO:0031625	ubiquitin protein ligase binding
1.59	2.74e-02	GO:0016563	transcription activator activity
2.81	3.15e-02	GO:0003823	antigen binding
1.24	3.29e-02	GO:0016740	transferase activity
1.44	3.63e-02	GO:0008092	cytoskeletal protein binding
2.65	4.93e-02	GO:0046332	SMAD binding