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• Activity deltas table
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Motif ID: ZNF423.p2

Z-value: 1.718

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_27952591	22.541	NM_001042747	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chrX_-_107019001	17.698	NM_198057	TSC22D3	TSC22 domain family, member 3
chr14_+_92790151	17.334	NM_153646	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr19_+_45971249	16.861	NM_001114171 NM_006732	FOSB	FBJ murine osteosarcoma viral oncogene homolog B
chr1_+_26644458	15.928		CD52	CD52 molecule
chr10_+_99079017	15.701	NM_005479	FRAT1	frequently rearranged in advanced T-cell lymphomas
chr5_+_150400132	14.052		GPX3	glutathione peroxidase 3 (plasma)
chr9_+_93564063	13.987		SYK	spleen tyrosine kinase
chr9_+_93564099	13.920		SYK	spleen tyrosine kinase
chr3_+_52529351	13.549	NM_015136	STAB1	stabilin 1
chr3_+_52529370	13.521		STAB1	stabilin 1
chr9_+_93564073	13.474		SYK	spleen tyrosine kinase
chr5_+_150399980	13.210	NM_002084	GPX3	glutathione peroxidase 3 (plasma)
chr16_+_70148213	12.494		PDPR	pyruvate dehydrogenase phosphatase regulatory subunit
chr9_+_93564204	12.020	NM_001174168	SYK	spleen tyrosine kinase
chr12_+_54332575	11.939	NM_017410	HOXC13	homeobox C13
chr19_-_2041862	11.914		MKNK2	MAP kinase interacting serine/threonine kinase 2
chrX_-_102319080	11.899		BEX1	brain expressed, X-linked 1
chr2_-_145274916	11.682		ZEB2	zinc finger E-box binding homeobox 2
chr8_-_133492556	11.557		KCNQ3	potassium voltage-gated channel, KQT-like subfamily, member 3
chr19_-_3786279	11.458		MATK	megakaryocyte-associated tyrosine kinase
chr11_+_1892098	11.371	NM_001013254 NM_001013255	LSP1	lymphocyte-specific protein 1
chr3_+_138067969	11.363	NM_001252090	MRAS	muscle RAS oncogene homolog
chr17_-_37764165	11.078	NM_006160	NEUROD2	neurogenic differentiation 2
chr5_+_170736287	10.815	NM_021025	TLX3	T-cell leukemia homeobox 3
chr16_-_74401991	10.574		LOC283922	pyruvate dehydrogenase phosphatase regulatory subunit pseudogene
chr1_+_26644380	10.546	NM_001803	CD52	CD52 molecule
chr8_-_121823696	10.541		SNTB1	syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chrX_-_51239426	10.247	NM_018159	NUDT11	nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr19_-_2042022	10.221		MKNK2	MAP kinase interacting serine/threonine kinase 2
chr6_+_89791510	10.216		PNRC1	proline-rich nuclear receptor coactivator 1
chr19_-_5622794	9.950	NM_014649	SAFB2	scaffold attachment factor B2
chr9_+_93564011	9.693	NM_001135052 NM_003177	SYK	spleen tyrosine kinase
chr15_-_75660944	9.649		MAN2C1	mannosidase, alpha, class 2C, member 1
chr19_+_50016500	9.628		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr3_+_133465250	9.596		TF	transferrin
chr1_-_156470506	9.526	NM_005920	MEF2D	myocyte enhancer factor 2D
chr22_+_22786283	9.379
chr9_-_100881515	9.297		TRIM14	tripartite motif containing 14
chr13_-_46626845	9.273	NM_015070	ZC3H13	zinc finger CCCH-type containing 13
chr3_+_32726659	9.221	NM_015442	CNOT10	CCR4-NOT transcription complex, subunit 10
chr19_+_50016490	9.091		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr3_+_133465204	9.091		TF	transferrin
chr6_+_33244916	9.048	NM_003782	B3GALT4	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
chr15_+_90931509	8.972		IQGAP1	IQ motif containing GTPase activating protein 1
chr19_+_58095507	8.626	NM_001010879	ZIK1	zinc finger protein interacting with K protein 1 homolog (mouse)
chr15_+_90931489	8.608		IQGAP1	IQ motif containing GTPase activating protein 1
chr11_+_14665308	8.570		PDE3B	phosphodiesterase 3B, cGMP-inhibited
chr3_-_58563070	8.539		FAM107A	family with sequence similarity 107, member A
chr12_-_120554558	8.492		RAB35	RAB35, member RAS oncogene family
chr4_-_169401571	8.487		DDX60L	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr11_+_14665338	8.486		PDE3B	phosphodiesterase 3B, cGMP-inhibited
chr8_-_133492751	8.404		KCNQ3	potassium voltage-gated channel, KQT-like subfamily, member 3
chr6_+_42897184	8.376		CNPY3	canopy 3 homolog (zebrafish)
chr20_+_30639981	8.341	NM_001172129 NM_001172130 NM_001172131 NM_001172132 NM_001172133 NM_002110	HCK	hemopoietic cell kinase
chr20_+_23015949	8.322	NM_001052	SSTR4	somatostatin receptor 4
chrX_-_107018889	8.075		TSC22D3	TSC22 domain family, member 3
chr14_-_60097314	7.982		RTN1	reticulon 1
chr2_-_206950895	7.820	NM_017759	INO80D	INO80 complex subunit D
chr5_+_141303366	7.805	NM_001142603 NM_014773	KIAA0141	KIAA0141
chr8_-_21966812	7.759	NM_024815	NUDT18	nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr19_+_39833096	7.754		SAMD4B	sterile alpha motif domain containing 4B
chr16_+_58498216	7.687		NDRG4	NDRG family member 4
chr12_-_120554551	7.645		RAB35	RAB35, member RAS oncogene family
chr5_-_140998480	7.577		DIAPH1	diaphanous homolog 1 (Drosophila)
chr12_-_6665220	7.496	NM_001039670 NM_001193457 NM_080730	IFFO1	intermediate filament family orphan 1
chr19_-_38714781	7.472	NM_001135155 NM_004647	DPF1	D4, zinc and double PHD fingers family 1
chr22_+_22735134	7.439		CYAT1	immunoglobulin lambda light chain-like
chr10_+_99894426	7.422		C10orf28	chromosome 10 open reading frame 28
chr20_-_23402038	7.343	NM_022080	NAPB	N-ethylmaleimide-sensitive factor attachment protein, beta
chr15_-_83316621	7.271	NM_030594	CPEB1	cytoplasmic polyadenylation element binding protein 1
chr15_+_64443909	7.241	NM_024798	SNX22	sorting nexin 22
chr12_-_120554453	7.233		RAB35	RAB35, member RAS oncogene family
chr9_-_37904098	7.221		MCART1	mitochondrial carrier triple repeat 1
chr19_+_45582469	7.174	NM_001007270 NM_001007269 NM_024707	GEMIN7	gem (nuclear organelle) associated protein 7
chr1_+_27719151	7.162	NM_005281	GPR3	G protein-coupled receptor 3
chr5_+_78407603	7.076	NM_001713	BHMT	betaine--homocysteine S-methyltransferase
chr3_-_50374749	7.026		RASSF1	Ras association (RalGDS/AF-6) domain family member 1
chr3_-_50374795	6.905		RASSF1	Ras association (RalGDS/AF-6) domain family member 1
chr1_-_156470538	6.871		MEF2D	myocyte enhancer factor 2D
chr22_-_20104745	6.848	NM_022727 NM_182984	TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr3_-_16555128	6.808	NM_015150	RFTN1	raftlin, lipid raft linker 1
chr12_-_120554557	6.806		RAB35	RAB35, member RAS oncogene family
chr5_-_176057324	6.772	NM_001001502 NM_003085	SNCB	synuclein, beta
chr5_+_176784843	6.765	NM_006480	RGS14	regulator of G-protein signaling 14
chrX_-_51239295	6.760		NUDT11	nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr16_+_28986024	6.743	NM_001142448 NM_001142449 NM_001142450 NM_001142451 NM_032038	SPIN1 SPNS1	spindlin 1 spinster homolog 1 (Drosophila)
chr19_-_3786382	6.712	NM_139354 NM_139355	MATK	megakaryocyte-associated tyrosine kinase
chr16_+_69796237	6.599	NM_007014 NM_199423	WWP2	WW domain containing E3 ubiquitin protein ligase 2
chr9_+_131549561	6.589		TBC1D13	TBC1 domain family, member 13
chr20_+_62368035	6.583		LIME1	Lck interacting transmembrane adaptor 1
chr19_-_10679620	6.578	NM_001800 NM_079421	CDKN2D	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr19_-_11689765	6.555	NM_001111035 NM_001111036	ACP5	acid phosphatase 5, tartrate resistant
chr14_-_53258329	6.513	NM_198066	GNPNAT1	glucosamine-phosphate N-acetyltransferase 1
chr9_+_4985243	6.509	NM_004972	JAK2	Janus kinase 2
chr18_-_51750460	6.500		MBD2	methyl-CpG binding domain protein 2
chr3_+_53529030	6.402	NM_000720 NM_001128839 NM_001128840	CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit
chr4_+_4388804	6.391		D4S234E	DNA segment on chromosome 4 (unique) 234 expressed sequence
chr2_+_242641310	6.376	NM_032329	ING5	inhibitor of growth family, member 5
chr5_+_141303463	6.367		KIAA0141	KIAA0141
chr17_+_18012019	6.352	NM_016239	MYO15A	myosin XVA
chr16_+_27325244	6.345	NM_000418 NM_001008699	IL4R	interleukin 4 receptor
chr19_+_14544100	6.313	NM_002741	PKN1	protein kinase N1
chr21_+_27012067	6.252		JAM2	junctional adhesion molecule 2
chr11_-_64684606	6.212	NM_015104	ATG2A	ATG2 autophagy related 2 homolog A (S. cerevisiae)
chr21_-_35831856	6.192	NM_001127668 NM_001127669	KCNE1	potassium voltage-gated channel, Isk-related family, member 1
chr7_-_100254048	6.178	NM_016188	ACTL6B	actin-like 6B
chr16_-_56459302	6.170		AMFR	autocrine motility factor receptor
chr8_-_80679897	6.151	NM_001040708 NM_012258	HEY1	hairy/enhancer-of-split related with YRPW motif 1
chr15_+_25200069	6.147	NM_003097 NM_022804 NM_005678	SNRPN SNURF	small nuclear ribonucleoprotein polypeptide N SNRPN upstream reading frame
chrX_+_70315637	6.111	NM_001170931 NM_005938	FOXO4	forkhead box O4
chr21_+_27011766	6.110		JAM2	junctional adhesion molecule 2
chr6_+_42897236	6.077		CNPY3	canopy 3 homolog (zebrafish)
chr9_-_139094886	6.069	NM_014564	LHX3	LIM homeobox 3
chr1_+_236849753	6.048	NM_001103	ACTN2	actinin, alpha 2
chr4_+_4388717	6.020		D4S234E	DNA segment on chromosome 4 (unique) 234 expressed sequence
chr3_-_16554992	6.008		RFTN1	raftlin, lipid raft linker 1
chr19_-_57183122	5.995	NM_001005850	ZNF835	zinc finger protein 835
chr9_+_137967401	5.966		OLFM1	olfactomedin 1
chr11_+_17757494	5.949	NM_001112741 NM_004976	KCNC1	potassium voltage-gated channel, Shaw-related subfamily, member 1
chr14_+_103995535	5.784		TRMT61A	tRNA methyltransferase 61 homolog A (S. cerevisiae)
chr11_+_12695851	5.748	NM_021961	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr11_+_14665268	5.732	NM_000922	PDE3B	phosphodiesterase 3B, cGMP-inhibited
chr1_+_110254863	5.692	NM_000851	GSTM5	glutathione S-transferase mu 5
chr11_+_819696	5.640		PNPLA2	patatin-like phospholipase domain containing 2
chr7_-_152373163	5.632	NM_005431	XRCC2	X-ray repair complementing defective repair in Chinese hamster cells 2
chr8_-_133493003	5.631	NM_004519	KCNQ3	potassium voltage-gated channel, KQT-like subfamily, member 3
chr3_+_6902812	5.612		GRM7	glutamate receptor, metabotropic 7
chr9_-_130742803	5.549	NM_001035254	FAM102A	family with sequence similarity 102, member A
chr19_+_39833099	5.545	NM_018028	SAMD4B	sterile alpha motif domain containing 4B
chr3_-_50374875	5.535	NM_170713	RASSF1	Ras association (RalGDS/AF-6) domain family member 1
chr20_-_23066828	5.520	NM_012072	CD93	CD93 molecule
chr9_-_91793375	5.503		SHC3	SHC (Src homology 2 domain containing) transforming protein 3
chr20_+_44650260	5.487	NM_001134771	SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5
chr19_-_11689591	5.486	NM_001111034	ACP5	acid phosphatase 5, tartrate resistant
chr14_+_103995473	5.465	NM_152307	TRMT61A	tRNA methyltransferase 61 homolog A (S. cerevisiae)
chr12_-_4554779	5.428	NM_020996	FGF6	fibroblast growth factor 6
chr22_-_20104695	5.427		TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr1_-_27953046	5.421	NM_001042729	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr1_-_212873197	5.379		BATF3	basic leucine zipper transcription factor, ATF-like 3
chr8_-_144241918	5.362	NM_001130478	LY6H	lymphocyte antigen 6 complex, locus H
chr19_-_36523540	5.343	NM_001199570	CLIP3	CAP-GLY domain containing linker protein 3
chr16_+_230332	5.341	NM_005331	HBQ1	hemoglobin, theta 1
chr5_+_176784947	5.301
chr22_+_37257004	5.298	NM_000631 NM_013416	NCF4	neutrophil cytosolic factor 4, 40kDa
chr20_+_24929862	5.296	NM_003650	CST7	cystatin F (leukocystatin)
chr9_+_131549509	5.290	NM_018201	TBC1D13	TBC1 domain family, member 13
chr19_+_36359346	5.286	NM_001024807 NM_005166	APLP1	amyloid beta (A4) precursor-like protein 1
chr9_-_100881462	5.258	NM_014788 NM_033219 NM_033220	TRIM14	tripartite motif containing 14
chr9_-_37904331	5.193	NM_033412	MCART1	mitochondrial carrier triple repeat 1
chr3_+_137483133	5.167	NM_004189	SOX14	SRY (sex determining region Y)-box 14
chr21_+_45719964	5.152		PFKL	phosphofructokinase, liver
chr18_-_5543967	5.146	NM_012307	EPB41L3	erythrocyte membrane protein band 4.1-like 3
chr21_+_47744032	5.144	NM_006031	PCNT	pericentrin
chr7_+_6629658	5.143	NM_024067	C7orf26	chromosome 7 open reading frame 26
chr19_-_5622725	5.140		SAFB2	scaffold attachment factor B2
chr16_-_56459371	5.123	NM_001144	AMFR	autocrine motility factor receptor
chrX_+_133507299	5.083	NM_001015877 NM_032335 NM_032458	PHF6	PHD finger protein 6
chr21_+_45719921	5.069	NM_002626	PFKL	phosphofructokinase, liver
chr15_-_79382839	5.050		RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1
chr14_-_53258145	5.044		GNPNAT1	glucosamine-phosphate N-acetyltransferase 1
chr19_+_22235278	5.031		ZNF257	zinc finger protein 257
chr6_-_32160289	5.008		GPSM3	G-protein signaling modulator 3
chr19_-_15311773	4.992	NM_000435	NOTCH3	notch 3
chr9_+_4985082	4.978		JAK2	Janus kinase 2
chr10_+_99894380	4.929	NM_014472	C10orf28	chromosome 10 open reading frame 28
chr9_+_6757919	4.917		KDM4C	lysine (K)-specific demethylase 4C
chr4_-_120549115	4.915	NM_033437	PDE5A	phosphodiesterase 5A, cGMP-specific
chr19_-_38806546	4.886	NM_001039672 NM_001039673 NM_001145463	YIF1B	Yip1 interacting factor homolog B (S. cerevisiae)
chr4_+_76439653	4.857	NM_144721	THAP6	THAP domain containing 6
chr19_-_12777540	4.845	NM_000528 NM_001173498	MAN2B1	mannosidase, alpha, class 2B, member 1
chr14_-_60097531	4.841	NM_206852	RTN1	reticulon 1
chr19_-_14117096	4.820	NM_002918	RFX1	regulatory factor X, 1 (influences HLA class II expression)
chr16_-_1843652	4.810	NM_001146006 NM_004970	IGFALS	insulin-like growth factor binding protein, acid labile subunit
chr11_+_76883823	4.807		MYO7A	myosin VIIA
chr4_+_71570768	4.804		RUFY3	RUN and FYVE domain containing 3
chrX_+_152770083	4.797		BGN	biglycan
chr19_-_16653202	4.790		CHERP	calcium homeostasis endoplasmic reticulum protein
chr7_-_100253976	4.769
chr10_+_88428263	4.762	NM_001080116 NM_001080114 NM_001080115 NM_001171611 NM_007078	LDB3	LIM domain binding 3
chr22_+_22735207	4.761		IGLJ3	immunoglobulin lambda joining 3
chr19_+_45754551	4.730		MARK4	MAP/microtubule affinity-regulating kinase 4
chr17_+_77020278	4.718		C1QTNF1	C1q and tumor necrosis factor related protein 1
chr19_+_55085237	4.708	NM_001130917 NM_006866	LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
chr19_+_22235253	4.699	NM_033468	ZNF257	zinc finger protein 257
chr15_-_75660905	4.685	NM_006715	MAN2C1	mannosidase, alpha, class 2C, member 1
chr19_-_46389307	4.683	NM_015649	IRF2BP1	interferon regulatory factor 2 binding protein 1
chr8_+_121823538	4.681
chr3_-_9885684	4.622		RPUSD3	RNA pseudouridylate synthase domain containing 3
chr14_-_60097223	4.606		RTN1	reticulon 1
chr14_+_65381178	4.599		CHURC1-FNTB CHURC1	CHURC1-FNTB readthrough churchill domain containing 1
chr11_+_819563	4.596		PNPLA2	patatin-like phospholipase domain containing 2
chr21_+_27012045	4.588		JAM2	junctional adhesion molecule 2
chr6_+_292033	4.581	NM_020185	DUSP22	dual specificity phosphatase 22
chr1_-_183559463	4.561		NCF2	neutrophil cytosolic factor 2
chr11_-_1036654	4.551	NM_005961	MUC6	mucin 6, oligomeric mucus/gel-forming
chr9_-_135230129	4.545		SETX	senataxin
chr16_+_71392615	4.544	NM_001740 NM_007088	CALB2	calbindin 2
chr8_-_145669796	4.535	NM_013432	TONSL	tonsoku-like, DNA repair protein
chr22_+_22735202	4.524

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.26	3.35e-12	GO:0065007	biological regulation
1.25	6.36e-10	GO:0050789	regulation of biological process
1.26	4.49e-09	GO:0050794	regulation of cellular process
1.14	1.14e-07	GO:0009987	cellular process
1.37	2.95e-07	GO:0032502	developmental process
1.35	3.07e-06	GO:0023052	signaling
1.32	8.66e-06	GO:0051716	cellular response to stimulus
1.35	1.03e-05	GO:0007275	multicellular organismal development
1.36	1.32e-05	GO:0007165	signal transduction
1.36	2.93e-05	GO:0048856	anatomical structure development
1.37	1.78e-04	GO:0048731	system development
1.53	3.02e-04	GO:0009653	anatomical structure morphogenesis
1.47	3.69e-04	GO:0007166	cell surface receptor linked signaling pathway
1.21	3.96e-04	GO:0050896	response to stimulus
1.39	4.59e-04	GO:0048519	negative regulation of biological process
1.23	6.38e-04	GO:0032501	multicellular organismal process
1.39	8.31e-04	GO:0042221	response to chemical stimulus
1.50	1.31e-03	GO:0007399	nervous system development
1.40	1.94e-03	GO:0048869	cellular developmental process
1.39	1.98e-03	GO:0048523	negative regulation of cellular process
1.39	2.28e-03	GO:0065008	regulation of biological quality
1.39	4.04e-03	GO:0030154	cell differentiation
1.73	6.00e-03	GO:0009719	response to endogenous stimulus
2.06	6.84e-03	GO:0071495	cellular response to endogenous stimulus
1.40	7.71e-03	GO:0048583	regulation of response to stimulus
1.25	8.69e-03	GO:0019222	regulation of metabolic process
1.32	1.02e-02	GO:0048518	positive regulation of biological process
1.68	1.35e-02	GO:0002682	regulation of immune system process
1.56	1.36e-02	GO:0009605	response to external stimulus
1.48	1.69e-02	GO:0051239	regulation of multicellular organismal process
1.31	1.75e-02	GO:0031326	regulation of cellular biosynthetic process
1.31	1.88e-02	GO:0009889	regulation of biosynthetic process
1.55	2.23e-02	GO:0006357	regulation of transcription from RNA polymerase II promoter
2.59	2.75e-02	GO:0060627	regulation of vesicle-mediated transport
1.26	2.80e-02	GO:0080090	regulation of primary metabolic process
1.87	2.87e-02	GO:0040008	regulation of growth
2.02	3.10e-02	GO:0032870	cellular response to hormone stimulus
1.30	3.59e-02	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.47	4.46e-07	GO:0044459	plasma membrane part
1.25	6.22e-04	GO:0005886	plasma membrane
1.24	9.75e-04	GO:0071944	cell periphery
1.47	4.12e-03	GO:0005887	integral to plasma membrane
1.44	9.90e-03	GO:0031226	intrinsic to plasma membrane
1.12	2.60e-02	GO:0005737	cytoplasm
1.74	4.30e-02	GO:0045202	synapse

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.19	6.28e-06	GO:0005515	protein binding
1.72	3.70e-04	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.78	4.96e-04	GO:0004672	protein kinase activity
1.62	5.68e-04	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.67	6.18e-04	GO:0016301	kinase activity
2.52	6.80e-03	GO:0022843	voltage-gated cation channel activity
1.08	7.83e-03	GO:0005488	binding
1.60	9.83e-03	GO:0015075	ion transmembrane transporter activity
1.63	1.10e-02	GO:0043565	sequence-specific DNA binding
4.14	1.10e-02	GO:0003823	antigen binding
1.50	1.70e-02	GO:0001071	nucleic acid binding transcription factor activity
1.50	1.70e-02	GO:0003700	sequence-specific DNA binding transcription factor activity
1.67	2.04e-02	GO:0008324	cation transmembrane transporter activity
1.35	2.97e-02	GO:0016740	transferase activity
1.56	3.27e-02	GO:0019899	enzyme binding