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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: bHLH_family.p2

Z-value: 3.919

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_-_58146108	283.386		CDK4	cyclin-dependent kinase 4
chr12_-_58146110	280.453		CDK4	cyclin-dependent kinase 4
chr12_-_58146025	280.326		CDK4	cyclin-dependent kinase 4
chr12_-_58146118	264.246	NM_000075	CDK4	cyclin-dependent kinase 4
chr2_+_216176818	89.213		ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr2_+_216176808	86.379		ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr17_+_76164624	83.300	NM_004710	SYNGR2	synaptogyrin 2
chr8_+_97274106	80.650		PTDSS1	phosphatidylserine synthase 1
chr2_+_216176678	76.734	NM_004044	ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr2_-_10588451	74.329	NM_002539	ODC1	ornithine decarboxylase 1
chr4_-_100871482	71.323	NM_002106	H2AFZ	H2A histone family, member Z
chr20_+_44519924	71.206		CTSA	cathepsin A
chr20_+_44519965	69.443		CTSA	cathepsin A
chr11_-_64014381	67.786		PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr14_+_20923705	66.832		APEX1	APEX nuclease (multifunctional DNA repair enzyme) 1
chr8_+_55047780	64.741	NM_014175	MRPL15	mitochondrial ribosomal protein L15
chr20_+_44519590	63.488	NM_000308 NM_001127695 NM_001167594	CTSA	cathepsin A
chr11_-_64014264	62.374		PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr14_+_20923364	61.603		APEX1	APEX nuclease (multifunctional DNA repair enzyme) 1
chr11_+_61560352	58.401		FEN1	flap structure-specific endonuclease 1
chr2_-_198364560	58.026		HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr14_+_20923341	57.854		APEX1	APEX nuclease (multifunctional DNA repair enzyme) 1
chr20_+_44520203	57.251		CTSA	cathepsin A
chr2_-_10588273	57.102		ODC1	ornithine decarboxylase 1
chr3_+_52719935	56.826	NM_014366 NM_206825 NM_206826	GNL3	guanine nucleotide binding protein-like 3 (nucleolar)
chr1_-_26233367	55.789	NM_203399	STMN1	stathmin 1
chr8_+_98656428	55.632		MTDH	metadherin
chr20_+_44520021	55.465		CTSA	cathepsin A
chr5_+_34656482	55.197		RAI14	retinoic acid induced 14
chr19_+_50180492	54.945		PRMT1	protein arginine methyltransferase 1
chr14_+_20923289	54.389	NM_001244249 NM_001641 NM_080648 NM_080649	APEX1	APEX nuclease (multifunctional DNA repair enzyme) 1
chr8_+_98656329	53.063	NM_178812	MTDH	metadherin
chr19_+_50180408	51.657	NM_001207042 NM_001536 NM_198318	PRMT1	protein arginine methyltransferase 1
chr19_+_10765106	51.572		ILF3	interleukin enhancer binding factor 3, 90kDa
chr7_-_99698993	51.156		MCM7	minichromosome maintenance complex component 7
chr11_-_64014140	51.097		PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr1_-_155231941	50.905		SCAMP3	secretory carrier membrane protein 3
chr7_-_99699030	50.514		MCM7	minichromosome maintenance complex component 7
chr1_-_78148326	50.229	NM_015534	ZZZ3	zinc finger, ZZ-type containing 3
chr4_-_100871431	49.853		H2AFZ	H2A histone family, member Z
chr6_-_43197178	49.727	NM_006443 NM_199184	C6orf108	chromosome 6 open reading frame 108
chr8_+_98656494	47.553		MTDH	metadherin
chr7_+_100464949	47.159	NM_003302	TRIP6	thyroid hormone receptor interactor 6
chr19_-_42806928	46.987	NM_001145939 NM_001145940	PAFAH1B3	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr1_-_159895258	46.704		TAGLN2	transgelin 2
chr5_-_61699598	46.572		DIMT1	DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
chr17_+_49230938	45.916		NME1 NME1-NME2	non-metastatic cells 1, protein (NM23A) expressed in NME1-NME2 readthrough
chr4_+_57301898	45.347	NM_006452	PAICS	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr8_+_22224997	45.132	NM_001135153	SLC39A14	solute carrier family 39 (zinc transporter), member 14
chr11_+_61560108	44.637	NM_004111	FEN1	flap structure-specific endonuclease 1
chr7_-_99698916	44.219		MCM7	minichromosome maintenance complex component 7
chr8_+_98788014	44.051		LAPTM4B	lysosomal protein transmembrane 4 beta
chr4_+_140222668	44.001	NM_057175	NAA15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr1_-_155232091	43.890	NM_005698 NM_052837	SCAMP3	secretory carrier membrane protein 3
chr1_+_44440623	43.584		ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr12_-_49318663	43.530	NM_001143781	FKBP11	FK506 binding protein 11, 19 kDa
chr1_-_26232890	43.473	NM_001145454 NM_005563	STMN1	stathmin 1
chr19_+_41256758	43.348	NM_004596	SNRPA	small nuclear ribonucleoprotein polypeptide A
chr17_+_49230954	43.184		NME1 NME1-NME2	non-metastatic cells 1, protein (NM23A) expressed in NME1-NME2 readthrough
chr2_+_113403433	43.059	NM_005415	SLC20A1	solute carrier family 20 (phosphate transporter), member 1
chr11_-_64014407	42.807	NM_138689	PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr17_+_49230929	42.764		NME1	non-metastatic cells 1, protein (NM23A) expressed in
chr1_-_159895279	42.313	NM_003564	TAGLN2	transgelin 2
chr8_+_22224758	41.764	NM_001128431 NM_001135154 NM_015359	SLC39A14	solute carrier family 39 (zinc transporter), member 14
chr11_+_61560401	40.579		FEN1	flap structure-specific endonuclease 1
chr5_+_34656595	40.552	NM_001145520	RAI14	retinoic acid induced 14
chrX_+_118602391	40.508		SLC25A5	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr1_-_155231994	40.110		SCAMP3	secretory carrier membrane protein 3
chr1_+_44440595	39.952	NM_001039457 NM_004047	ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr3_+_49059046	39.354	NM_199069 NM_199070	NDUFAF3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr16_-_103557	39.296	NM_016310	POLR3K	polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
chr13_+_76123885	39.292	NM_006002	UCHL3	ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr1_-_8938745	39.205		ENO1	enolase 1, (alpha)
chr12_+_6833425	38.432	NM_001164093	COPS7A	COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
chr11_+_69455837	38.136	NM_053056	CCND1	cyclin D1
chr1_+_182992694	38.116
chr12_+_53645369	38.096	NM_001170790	MFSD5	major facilitator superfamily domain containing 5
chr17_+_49230896	37.570	NM_000269 NM_198175 NM_001018136	NME1 NME1-NME2	non-metastatic cells 1, protein (NM23A) expressed in NME1-NME2 readthrough
chr16_+_103009	37.306		SNRNP25	small nuclear ribonucleoprotein 25kDa (U11/U12)
chr1_-_78149093	37.288		ZZZ3	zinc finger, ZZ-type containing 3
chr6_-_33386064	37.212	NM_001014433 NM_001014837 NM_001014838 NM_001014840 NM_015921	CUTA	cutA divalent cation tolerance homolog (E. coli)
chr6_+_44191504	37.111		SLC29A1	solute carrier family 29 (nucleoside transporters), member 1
chr16_+_23690234	37.065		PLK1	polo-like kinase 1
chr11_+_118958696	37.012	NM_001024382	HMBS	hydroxymethylbilane synthase
chr9_-_34048887	37.005	NM_018449	UBAP2	ubiquitin associated protein 2
chr3_+_49059490	36.736		NDUFAF3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr16_+_23690160	36.732		PLK1	polo-like kinase 1
chr5_+_34656367	36.082	NM_001145522 NM_015577	RAI14	retinoic acid induced 14
chr1_-_8938727	36.055		ENO1	enolase 1, (alpha)
chr6_+_44191276	35.930	NM_001078175 NM_001078176 NM_001078177	SLC29A1	solute carrier family 29 (nucleoside transporters), member 1
chr2_-_198364522	35.672		HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr20_+_48552902	35.626	NM_018683	RNF114	ring finger protein 114
chr4_-_100871418	35.506		H2AFZ	H2A histone family, member Z
chr17_-_5342424	35.452	NM_001212	C1QBP	complement component 1, q subcomponent binding protein
chr1_+_44440673	35.248		ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chrX_+_131157635	35.087	NM_001042452	MST4	serine/threonine protein kinase MST4
chr9_+_131452253	34.844	NM_001248001	SET	SET nuclear oncogene
chr2_-_198364623	34.681	NM_002156	HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr6_-_97345747	34.650		NDUFAF4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4
chrX_+_118602362	34.479	NM_001152	SLC25A5	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr1_-_40042072	34.313		PABPC4	poly(A) binding protein, cytoplasmic 4 (inducible form)
chr6_-_17706617	34.142	NM_005124	NUP153	nucleoporin 153kDa
chr1_+_44440642	34.032		ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr5_-_150466696	33.949	NM_001252391 NM_001252392	TNIP1	TNFAIP3 interacting protein 1
chr6_-_33385662	33.722		CUTA	cutA divalent cation tolerance homolog (E. coli)
chr4_-_47465646	33.560	NM_017845	COMMD8	COMM domain containing 8
chr1_-_8938691	33.508		ENO1	enolase 1, (alpha)
chr19_+_47634044	33.507	NM_001145713 NM_001145714 NM_005500	SAE1	SUMO1 activating enzyme subunit 1
chrX_+_23685613	33.292		PRDX4	peroxiredoxin 4
chr11_-_118972529	33.155		DPAGT1	dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr3_-_49066760	33.148		IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2
chr16_+_103827	33.103	NM_024571	SNRNP25	small nuclear ribonucleoprotein 25kDa (U11/U12)
chr16_+_23690191	33.086	NM_005030	PLK1	polo-like kinase 1
chr7_-_23509972	33.053	NM_006547	IGF2BP3	insulin-like growth factor 2 mRNA binding protein 3
chr11_-_64084980	32.914	NM_016404	TRMT112	tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr11_-_36310974	32.831	NM_001101653 NM_014186	COMMD9	COMM domain containing 9
chr12_+_49658862	32.631	NM_032704	TUBA1C	tubulin, alpha 1c
chr1_+_43148359	32.583		YBX1	Y box binding protein 1
chr17_+_7476023	32.395	NM_001204510 NM_001416	EIF4A1	eukaryotic translation initiation factor 4A1
chr11_-_118972784	32.141	NM_001382	DPAGT1	dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr7_-_105162551	32.076	NM_019042	PUS7	pseudouridylate synthase 7 homolog (S. cerevisiae)
chr4_-_99850280	31.990		EIF4E	eukaryotic translation initiation factor 4E
chr16_+_103859	31.897		SNRNP25	small nuclear ribonucleoprotein 25kDa (U11/U12)
chr4_-_47465719	31.863		COMMD8	COMM domain containing 8
chr2_-_61764661	31.860		XPO1	exportin 1 (CRM1 homolog, yeast)
chr16_+_103892	31.811		SNRNP25	small nuclear ribonucleoprotein 25kDa (U11/U12)
chr16_+_23690190	31.671		PLK1	polo-like kinase 1
chr6_-_109703661	31.639		CD164	CD164 molecule, sialomucin
chr17_+_49244082	31.521	NM_001018138	NME2	non-metastatic cells 2, protein (NM23B) expressed in
chrX_+_23685658	31.313		PRDX4	peroxiredoxin 4
chr1_-_26232643	31.307	NM_203401	STMN1	stathmin 1
chr6_-_33385814	31.305
chr19_+_54695103	31.267	NM_001077446	TSEN34	tRNA splicing endonuclease 34 homolog (S. cerevisiae)
chr3_-_50360109	31.243	NM_003773 NM_033158	HYAL2	hyaluronoglucosaminidase 2
chrX_+_23685637	31.241	NM_006406	PRDX4	peroxiredoxin 4
chr15_+_44084517	31.077	NM_001199878	SERF2-C15ORF63 SERF2	SERF2-C15orf63 readthrough small EDRK-rich factor 2
chr1_-_11120001	31.029		SRM	spermidine synthase
chr16_+_23690212	31.021		PLK1	polo-like kinase 1
chr12_-_123380608	30.983
chr8_+_22224786	30.747		SLC39A14	solute carrier family 39 (zinc transporter), member 14
chr17_-_46688362	30.426	NM_004502	HOXB7	homeobox B7
chr5_+_179126009	30.323		CANX	calnexin
chr12_-_46662779	30.266		SLC38A1	solute carrier family 38, member 1
chr6_-_8102753	30.167	NM_001135650 NM_004280	EEF1E1	eukaryotic translation elongation factor 1 epsilon 1
chr6_-_97345760	30.014	NM_014165	NDUFAF4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4
chr1_-_110950241	29.999		HBXIP	hepatitis B virus x interacting protein
chr8_+_97274137	29.880		PTDSS1	phosphatidylserine synthase 1
chr8_+_22436253	29.564	NM_021630	PDLIM2	PDZ and LIM domain 2 (mystique)
chr11_+_18344113	29.557		GTF2H1	general transcription factor IIH, polypeptide 1, 62kDa
chr17_+_49243632	29.333	NM_001198682 NM_002512	NME2	non-metastatic cells 2, protein (NM23B) expressed in
chr11_-_47664014	29.234	NM_014342	MTCH2	mitochondrial carrier 2
chr1_+_166808721	29.151	NM_017542	POGK	pogo transposable element with KRAB domain
chr5_+_110074708	29.030		SLC25A46	solute carrier family 25, member 46
chr2_+_198365012	28.996		HSPE1	heat shock 10kDa protein 1 (chaperonin 10)
chr6_-_28891409	28.965		TRIM27	tripartite motif containing 27
chr1_+_218458646	28.941		RRP15	ribosomal RNA processing 15 homolog (S. cerevisiae)
chr1_+_154193757	28.787		UBAP2L	ubiquitin associated protein 2-like
chr19_-_8386245	28.698		NDUFA7	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
chr19_+_797390	28.667	NM_002819 NM_031990 NM_031991 NM_175847	PTBP1	polypyrimidine tract binding protein 1
chr12_-_65153189	28.514	NM_002076	GNS	glucosamine (N-acetyl)-6-sulfatase
chr1_-_150669499	28.337	NM_018178	GOLPH3L	golgi phosphoprotein 3-like
chr5_+_110074740	28.170	NM_138773	SLC25A46	solute carrier family 25, member 46
chr8_+_145582208	28.113	NM_001253816 NM_001253815	GPR172A	G protein-coupled receptor 172A
chr4_+_57302448	28.111		PAICS	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr10_+_75910908	28.045	NM_001202450 NM_006721	ADK	adenosine kinase
chr12_-_102512277	27.952	NM_024057	NUP37	nucleoporin 37kDa
chr17_+_49243770	27.763	NM_001018139	NME2	non-metastatic cells 2, protein (NM23B) expressed in
chr9_-_34637623	27.640		SIGMAR1	sigma non-opioid intracellular receptor 1
chr14_-_58894217	27.558	NM_012460	TIMM9	translocase of inner mitochondrial membrane 9 homolog (yeast)
chr20_+_48552935	27.522		RNF114	ring finger protein 114
chr22_-_42343079	27.445	NM_001002876 NM_024053	CENPM	centromere protein M
chr9_-_34637752	27.285	NM_005866 NM_147157	SIGMAR1	sigma non-opioid intracellular receptor 1
chr3_+_158519888	27.209		MFSD1	major facilitator superfamily domain containing 1
chr8_-_103667882	27.024	NM_005655	KLF10	Kruppel-like factor 10
chr3_+_184032849	26.927	NM_182917	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr19_+_47634133	26.920		SAE1	SUMO1 activating enzyme subunit 1
chr4_-_157892545	26.836	NM_016205	PDGFC	platelet derived growth factor C
chr3_-_49066813	26.795		IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2
chr3_+_158519877	26.794		MFSD1	major facilitator superfamily domain containing 1
chr12_+_131356557	26.554	NM_006325	RAN	RAN, member RAS oncogene family
chrX_+_131157231	26.517	NM_001042453 NM_016542	MST4	serine/threonine protein kinase MST4
chr3_+_158519714	26.330	NM_001167903 NM_022736	MFSD1	major facilitator superfamily domain containing 1
chr20_+_17550598	26.163	NM_001011546 NM_006870	DSTN	destrin (actin depolymerizing factor)
chr19_+_49458151	26.141		BAX	BCL2-associated X protein
chr1_-_183604850	26.110		ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa
chr2_+_198364720	26.094	NM_001202485 NM_002157	HSPE1-MOB4 HSPE1	HSPE1-MOB4 readthrough heat shock 10kDa protein 1 (chaperonin 10)
chr19_-_8386273	25.928	NM_005001	NDUFA7	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
chr17_+_55163077	25.909	NM_001242903 NM_001242902	AKAP1	A kinase (PRKA) anchor protein 1
chr10_-_120840241	25.819		EIF3A	eukaryotic translation initiation factor 3, subunit A
chr1_-_183604885	25.778	NM_005717	ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa
chr2_+_198365113	25.590		HSPE1	heat shock 10kDa protein 1 (chaperonin 10)
chr1_+_214776494	25.531	NM_016343	CENPF	centromere protein F, 350/400kDa (mitosin)
chr8_+_97274158	25.295	NM_014754	PTDSS1	phosphatidylserine synthase 1
chr9_+_117350097	25.257		ATP6V1G1	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr12_+_53342842	25.219	NM_000224	KRT18	keratin 18
chr16_-_81129882	25.113	NM_004483	GCSH	glycine cleavage system protein H (aminomethyl carrier)
chr15_-_72523713	25.050	NM_001206796 NM_001206797 NM_001206798 NM_002654 NM_182470 NM_182471	PKM2	pyruvate kinase, muscle
chr2_+_29117503	24.996	NM_015131	WDR43	WD repeat domain 43
chr20_+_48552928	24.985		RNF114	ring finger protein 114
chr7_+_16685757	24.963	NM_001159767 NM_014038	BZW2	basic leucine zipper and W2 domains 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.25	3.85e-51	GO:0009987	cellular process
1.46	1.71e-48	GO:0044237	cellular metabolic process
1.38	6.40e-41	GO:0008152	metabolic process
1.40	2.65e-36	GO:0044238	primary metabolic process
1.63	1.12e-34	GO:0006807	nitrogen compound metabolic process
1.64	4.99e-34	GO:0034641	cellular nitrogen compound metabolic process
1.50	2.11e-33	GO:0044260	cellular macromolecule metabolic process
1.66	7.04e-31	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.42	1.12e-27	GO:0043170	macromolecule metabolic process
1.68	1.03e-24	GO:0090304	nucleic acid metabolic process
1.68	1.13e-19	GO:0010467	gene expression
1.70	3.51e-19	GO:0016070	RNA metabolic process
1.55	1.14e-17	GO:0044249	cellular biosynthetic process
1.52	1.04e-16	GO:0009058	biosynthetic process
1.41	1.22e-15	GO:0071840	cellular component organization or biogenesis
1.47	7.00e-15	GO:0071841	cellular component organization or biogenesis at cellular level
2.08	1.13e-14	GO:0006396	RNA processing
1.73	1.75e-13	GO:0044085	cellular component biogenesis
1.37	4.32e-12	GO:0016043	cellular component organization
1.45	5.56e-12	GO:0044267	cellular protein metabolic process
1.54	6.60e-12	GO:0044281	small molecule metabolic process
1.41	1.32e-10	GO:0071842	cellular component organization at cellular level
1.54	1.98e-10	GO:0034645	cellular macromolecule biosynthetic process
1.52	4.87e-10	GO:0009059	macromolecule biosynthetic process
1.98	1.33e-09	GO:0016071	mRNA metabolic process
1.61	1.23e-08	GO:0044248	cellular catabolic process
1.53	1.71e-08	GO:0009056	catabolic process
2.58	2.25e-08	GO:0022613	ribonucleoprotein complex biogenesis
3.01	3.28e-08	GO:0042254	ribosome biogenesis
2.49	7.10e-08	GO:0071843	cellular component biogenesis at cellular level
1.48	8.33e-08	GO:0006996	organelle organization
1.40	1.21e-07	GO:0048523	negative regulation of cellular process
1.33	1.21e-07	GO:0019538	protein metabolic process
1.60	2.79e-07	GO:0022607	cellular component assembly
2.22	5.40e-07	GO:0034660	ncRNA metabolic process
2.05	6.06e-07	GO:0044419	interspecies interaction between organisms
2.47	8.07e-07	GO:0034470	ncRNA processing
1.68	1.04e-06	GO:0046907	intracellular transport
2.12	1.09e-06	GO:0006412	translation
1.77	1.33e-06	GO:0009057	macromolecule catabolic process
1.35	1.73e-06	GO:0048522	positive regulation of cellular process
1.28	1.74e-06	GO:0051179	localization
1.36	1.95e-06	GO:0048519	negative regulation of biological process
1.15	3.36e-06	GO:0065007	biological regulation
1.63	3.38e-06	GO:0043933	macromolecular complex subunit organization
1.63	3.93e-06	GO:0033554	cellular response to stress
1.81	4.77e-06	GO:0044265	cellular macromolecule catabolic process
1.94	7.52e-06	GO:0006397	mRNA processing
1.55	7.70e-06	GO:0007049	cell cycle
1.65	9.97e-06	GO:0071844	cellular component assembly at cellular level
1.48	1.20e-05	GO:0051641	cellular localization
1.73	1.45e-05	GO:0071822	protein complex subunit organization
1.31	1.79e-05	GO:0048518	positive regulation of biological process
1.15	2.28e-05	GO:0050789	regulation of biological process
1.72	2.59e-05	GO:0006259	DNA metabolic process
1.16	3.05e-05	GO:0050794	regulation of cellular process
1.51	3.22e-05	GO:0051649	establishment of localization in cell
1.73	3.98e-05	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
1.54	4.13e-05	GO:0009892	negative regulation of metabolic process
1.28	4.23e-05	GO:0006810	transport
1.56	4.95e-05	GO:0010605	negative regulation of macromolecule metabolic process
2.00	6.46e-05	GO:0008380	RNA splicing
1.28	6.53e-05	GO:0051234	establishment of localization
1.65	9.65e-05	GO:0046483	heterocycle metabolic process
1.56	1.19e-04	GO:0008219	cell death
2.50	1.20e-04	GO:0007005	mitochondrion organization
2.57	1.25e-04	GO:0006403	RNA localization
2.89	1.30e-04	GO:0006364	rRNA processing
1.75	1.33e-04	GO:0034621	cellular macromolecular complex subunit organization
2.58	1.61e-04	GO:0050657	nucleic acid transport
2.58	1.61e-04	GO:0050658	RNA transport
2.58	1.61e-04	GO:0051236	establishment of RNA localization
1.55	1.65e-04	GO:0016265	death
2.19	1.82e-04	GO:0000375	RNA splicing, via transesterification reactions
1.43	2.33e-04	GO:0033036	macromolecule localization
1.79	2.64e-04	GO:0072521	purine-containing compound metabolic process
2.41	3.63e-04	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
1.52	3.74e-04	GO:0031324	negative regulation of cellular metabolic process
2.73	5.32e-04	GO:0016072	rRNA metabolic process
1.59	5.85e-04	GO:0065003	macromolecular complex assembly
1.82	6.90e-04	GO:0044271	cellular nitrogen compound biosynthetic process
1.43	9.32e-04	GO:0031325	positive regulation of cellular metabolic process
2.16	9.42e-04	GO:0022411	cellular component disassembly
2.16	9.42e-04	GO:0071845	cellular component disassembly at cellular level
1.30	1.12e-03	GO:0042221	response to chemical stimulus
2.04	1.26e-03	GO:0051186	cofactor metabolic process
2.12	1.41e-03	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.12	1.41e-03	GO:0000398	nuclear mRNA splicing, via spliceosome
1.45	1.63e-03	GO:0008104	protein localization
1.60	1.88e-03	GO:0051726	regulation of cell cycle
1.87	2.32e-03	GO:0051325	interphase
1.71	2.40e-03	GO:0008283	cell proliferation
1.87	2.67e-03	GO:0051329	interphase of mitotic cell cycle
1.65	3.42e-03	GO:0006753	nucleoside phosphate metabolic process
1.65	3.42e-03	GO:0009117	nucleotide metabolic process
1.81	3.58e-03	GO:0009259	ribonucleotide metabolic process
1.69	3.80e-03	GO:0016044	cellular membrane organization
1.69	4.66e-03	GO:0061024	membrane organization
1.72	4.77e-03	GO:0016032	viral reproduction
4.09	4.78e-03	GO:0043488	regulation of mRNA stability
1.27	4.88e-03	GO:0006950	response to stress
2.75	4.93e-03	GO:0006839	mitochondrial transport
1.39	5.00e-03	GO:0009893	positive regulation of metabolic process
1.48	5.56e-03	GO:0045184	establishment of protein localization
1.49	5.84e-03	GO:0022402	cell cycle process
1.19	7.14e-03	GO:0051716	cellular response to stimulus
1.93	7.25e-03	GO:0032269	negative regulation of cellular protein metabolic process
1.86	7.99e-03	GO:0010608	posttranscriptional regulation of gene expression
3.95	7.99e-03	GO:0043487	regulation of RNA stability
1.44	8.14e-03	GO:0032774	RNA biosynthetic process
1.42	8.24e-03	GO:0042981	regulation of apoptosis
1.47	9.08e-03	GO:0015031	protein transport
1.53	1.00e-02	GO:0022403	cell cycle phase
1.44	1.07e-02	GO:0042127	regulation of cell proliferation
1.92	1.09e-02	GO:0018130	heterocycle biosynthetic process
1.89	1.24e-02	GO:0051248	negative regulation of protein metabolic process
1.41	1.36e-02	GO:0043067	regulation of programmed cell death
1.41	1.42e-02	GO:0010941	regulation of cell death
2.07	1.45e-02	GO:0006732	coenzyme metabolic process
1.62	1.67e-02	GO:0006461	protein complex assembly
1.59	1.68e-02	GO:0044282	small molecule catabolic process
1.77	1.84e-02	GO:0009150	purine ribonucleotide metabolic process
1.74	1.85e-02	GO:0006520	cellular amino acid metabolic process
3.39	1.86e-02	GO:0006413	translational initiation
2.92	1.94e-02	GO:0009119	ribonucleoside metabolic process
1.29	1.95e-02	GO:0043412	macromolecule modification
2.42	2.02e-02	GO:0006414	translational elongation
1.61	2.20e-02	GO:0070271	protein complex biogenesis
1.23	2.32e-02	GO:0048731	system development
1.66	2.40e-02	GO:0044106	cellular amine metabolic process
1.59	2.70e-02	GO:0044283	small molecule biosynthetic process
1.58	2.85e-02	GO:0006974	response to DNA damage stimulus
1.67	2.93e-02	GO:0006163	purine nucleotide metabolic process
1.59	2.95e-02	GO:0009308	amine metabolic process
1.21	3.01e-02	GO:0048856	anatomical structure development
1.55	3.09e-02	GO:0000278	mitotic cell cycle
5.64	4.15e-02	GO:0042451	purine nucleoside biosynthetic process
5.64	4.15e-02	GO:0042455	ribonucleoside biosynthetic process
5.64	4.15e-02	GO:0046129	purine ribonucleoside biosynthetic process
1.47	4.19e-02	GO:0016192	vesicle-mediated transport
2.29	4.30e-02	GO:0032984	macromolecular complex disassembly
2.29	4.30e-02	GO:0034623	cellular macromolecular complex disassembly
1.61	4.31e-02	GO:0044262	cellular carbohydrate metabolic process
3.91	4.91e-02	GO:0009156	ribonucleoside monophosphate biosynthetic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.23	9.17e-49	GO:0044424	intracellular part
1.34	4.89e-47	GO:0005737	cytoplasm
1.21	4.86e-45	GO:0005622	intracellular
1.45	8.90e-40	GO:0044446	intracellular organelle part
1.44	2.86e-39	GO:0044422	organelle part
1.41	5.30e-37	GO:0044444	cytoplasmic part
1.23	6.87e-30	GO:0043229	intracellular organelle
1.23	1.11e-29	GO:0043226	organelle
1.73	2.71e-29	GO:0044428	nuclear part
1.68	7.08e-28	GO:0031974	membrane-enclosed lumen
1.24	1.54e-26	GO:0043231	intracellular membrane-bounded organelle
1.24	1.58e-26	GO:0043227	membrane-bounded organelle
1.70	9.22e-26	GO:0005829	cytosol
1.65	1.94e-25	GO:0043233	organelle lumen
1.66	3.39e-25	GO:0070013	intracellular organelle lumen
1.72	9.19e-24	GO:0031981	nuclear lumen
1.47	8.46e-23	GO:0032991	macromolecular complex
2.23	4.69e-16	GO:0005730	nucleolus
1.44	3.31e-14	GO:0043228	non-membrane-bounded organelle
1.44	3.31e-14	GO:0043232	intracellular non-membrane-bounded organelle
1.94	1.04e-13	GO:0031967	organelle envelope
1.41	1.15e-13	GO:0043234	protein complex
1.26	1.92e-13	GO:0005634	nucleus
1.65	2.24e-13	GO:0005654	nucleoplasm
1.92	2.38e-13	GO:0031975	envelope
2.08	1.13e-12	GO:0030529	ribonucleoprotein complex
1.43	8.41e-10	GO:0031090	organelle membrane
1.51	3.72e-08	GO:0005739	mitochondrion
1.05	2.53e-07	GO:0044464	cell part
1.05	2.65e-07	GO:0005623	cell
1.85	7.96e-07	GO:0005740	mitochondrial envelope
6.11	2.27e-06	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
1.65	5.31e-06	GO:0044429	mitochondrial part
2.13	6.59e-06	GO:0005635	nuclear envelope
1.81	7.35e-06	GO:0031966	mitochondrial membrane
1.90	2.13e-05	GO:0019866	organelle inner membrane
1.37	1.04e-04	GO:0012505	endomembrane system
1.54	3.79e-04	GO:0044451	nucleoplasm part
1.82	7.59e-04	GO:0005743	mitochondrial inner membrane
1.40	1.06e-03	GO:0000267	cell fraction
2.57	1.33e-03	GO:0042470	melanosome
2.57	1.33e-03	GO:0048770	pigment granule
1.66	1.13e-02	GO:0048471	perinuclear region of cytoplasm
1.41	1.20e-02	GO:0005626	insoluble fraction
5.21	1.53e-02	GO:0005852	eukaryotic translation initiation factor 3 complex
1.41	2.31e-02	GO:0005624	membrane fraction
3.72	3.08e-02	GO:0044452	nucleolar part
1.34	3.42e-02	GO:0005783	endoplasmic reticulum
2.35	3.58e-02	GO:0046930	pore complex
5.39	3.74e-02	GO:0005732	small nucleolar ribonucleoprotein complex
3.24	3.91e-02	GO:0042645	mitochondrial nucleoid

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.44	1.24e-61	GO:0005515	protein binding
1.16	9.99e-27	GO:0005488	binding
1.86	2.08e-13	GO:0003723	RNA binding
1.20	5.39e-07	GO:0003824	catalytic activity
1.35	7.87e-07	GO:0000166	nucleotide binding
2.16	3.79e-03	GO:0003714	transcription corepressor activity
1.29	8.25e-03	GO:0016740	transferase activity
1.28	8.95e-03	GO:0032553	ribonucleotide binding
1.28	8.95e-03	GO:0032555	purine ribonucleotide binding
1.28	9.48e-03	GO:0035639	purine ribonucleoside triphosphate binding
1.51	9.99e-03	GO:0005198	structural molecule activity
2.51	1.28e-02	GO:0008135	translation factor activity, nucleic acid binding
1.65	1.31e-02	GO:0003712	transcription cofactor activity
1.27	1.37e-02	GO:0017076	purine nucleotide binding
1.45	1.40e-02	GO:0042802	identical protein binding
1.65	1.44e-02	GO:0000988	protein binding transcription factor activity
1.65	1.44e-02	GO:0000989	transcription factor binding transcription factor activity
3.29	2.86e-02	GO:0004536	deoxyribonuclease activity
1.42	4.01e-02	GO:0019899	enzyme binding