Motif ID: AAGUGCU

Z-value: 1.087


Mature miRNA associated with seed AAGUGCU:

NamemiRBase Accession
hsa-miR-302a MIMAT0000684
hsa-miR-302b MIMAT0000715
hsa-miR-302c MIMAT0000717
hsa-miR-302d MIMAT0000718
hsa-miR-302e MIMAT0005931
hsa-miR-372 MIMAT0000724
hsa-miR-373 MIMAT0000726
hsa-miR-520a-3p MIMAT0002834
hsa-miR-520b MIMAT0002843
hsa-miR-520c-3p MIMAT0002846
hsa-miR-520d-3p MIMAT0002856
hsa-miR-520e MIMAT0002825



Activity profile for motif AAGUGCU.

activity profile for motif AAGUGCU


Sorted Z-values histogram for motif AAGUGCU

Sorted Z-values for motif AAGUGCU



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGUGCU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_60337350 21.858 NM_021136
RTN1
reticulon 1
chr14_-_60097531 18.343 NM_206852
RTN1
reticulon 1
chr1_+_145438437 16.776 NM_006472
TXNIP
thioredoxin interacting protein
chr12_-_45269340 15.805 NM_001145109
NELL2
NEL-like 2 (chicken)
chr12_-_45270157 15.646 NM_001145108
NM_006159
NELL2

NEL-like 2 (chicken)

chr12_-_45270632 13.583 NM_001145107
NELL2
NEL-like 2 (chicken)
chr12_-_45307710 13.538 NM_001145110
NELL2
NEL-like 2 (chicken)
chr3_-_57113292 13.018 NM_001128615
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr20_-_4804067 12.825 NM_014737
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr12_-_16760935 12.655 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr3_-_13114547 12.413 NM_001134382
IQSEC1
IQ motif and Sec7 domain 1
chr3_-_13008959 11.463 NM_014869
IQSEC1
IQ motif and Sec7 domain 1
chr20_-_4795768 11.400 NM_170774
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr4_-_44728518 10.661 NM_138335
GNPDA2
glucosamine-6-phosphate deaminase 2
chr2_-_96811138 10.563 NM_004418
DUSP2
dual specificity phosphatase 2
chr6_+_41040687 10.357 NM_002505
NM_021705
NFYA

nuclear transcription factor Y, alpha

chr12_-_16759531 10.186 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_+_4382882 9.830 NM_001759
CCND2
cyclin D2
chr3_-_56835829 9.688 NM_019555
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr3_+_43328001 9.660 NM_001100594
NM_017719
SNRK

SNF related kinase

chr1_-_23857711 9.631 NM_004091
E2F2
E2F transcription factor 2
chr5_-_134914968 9.627 NM_004887
CXCL14
chemokine (C-X-C motif) ligand 14
chr16_-_2185824 9.383 NM_000296
NM_001009944
PKD1

polycystic kidney disease 1 (autosomal dominant)

chr11_-_133402227 9.370 NM_001012393
OPCML
opioid binding protein/cell adhesion molecule-like
chr16_+_85061303 9.315 NM_014732
KIAA0513
KIAA0513
chr15_+_31619043 9.050 NM_015995
KLF13
Kruppel-like factor 13
chr10_-_61469322 8.711 NM_194298
LOC100129721
SLC16A9
uncharacterized LOC100129721
solute carrier family 16, member 9 (monocarboxylic acid transporter 9)
chr14_-_45431121 8.630 NM_017658
KLHL28
kelch-like 28 (Drosophila)
chr13_-_26796343 8.407 NM_005977
RNF6
ring finger protein (C3H2C3 type) 6
chr11_-_132812870 8.397 NM_002545
OPCML
opioid binding protein/cell adhesion molecule-like
chr14_+_24630421 8.392 NM_006084
IRF9
interferon regulatory factor 9
chr1_-_230513390 8.385 NM_024554
PGBD5
piggyBac transposable element derived 5
chr1_-_114354906 8.326 NM_018364
RSBN1
round spermatid basic protein 1
chr4_-_176734181 8.277 NM_201591
GPM6A
glycoprotein M6A
chr20_+_36149606 8.081 NM_005386
NM_181689
NNAT

neuronatin

chr15_+_68871285 8.038 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr17_+_53342320 8.029 NM_002126
HLF
hepatic leukemia factor
chr6_-_32095993 8.025 NM_001136153
NM_004381
ATF6B

activating transcription factor 6 beta

chr9_-_23821842 7.986 NM_001171195
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr3_+_23987514 7.958 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr8_+_28747885 7.716 NM_001135726
HMBOX1
homeobox containing 1
chr3_-_56809594 7.649 NM_001128616
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr9_+_82186846 7.528 NM_007005
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr3_-_50605062 7.454 NM_001171740
NM_001171743
NM_016210
C3orf18


chromosome 3 open reading frame 18


chr2_-_240322620 7.450 NM_006037
HDAC4
histone deacetylase 4
chr15_-_83316621 7.410 NM_030594
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr5_+_74807580 7.368 NM_016218
POLK
polymerase (DNA directed) kappa
chr11_+_76156059 7.367 NM_020193
C11orf30
chromosome 11 open reading frame 30
chr14_+_71108373 7.209 NM_015351
TTC9
tetratricopeptide repeat domain 9
chr15_+_68924326 7.142 NM_001190457
CORO2B
coronin, actin binding protein, 2B
chr17_+_7184978 7.141 NM_001042
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr1_-_155532322 7.033 NM_018489
ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chr7_+_86781869 6.946 NM_021145
DMTF1
cyclin D binding myb-like transcription factor 1
chr13_-_46626845 6.934 NM_015070
ZC3H13
zinc finger CCCH-type containing 13
chr14_-_53620032 6.831 NM_001160147
NM_001160148
NM_030637
DDHD1


DDHD domain containing 1


chr1_-_45956795 6.763 NM_007170
TESK2
testis-specific kinase 2
chr2_+_198669316 6.745 NM_006226
PLCL1
phospholipase C-like 1
chr3_-_15106806 6.715 NM_022497
MRPS25
mitochondrial ribosomal protein S25
chr7_+_138916230 6.694 NM_173569
UBN2
ubinuclein 2
chr15_+_68908878 6.689 NM_001190456
CORO2B
coronin, actin binding protein, 2B
chr3_-_187463474 6.676 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr5_-_88179278 6.585 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr7_+_149535508 6.573 NM_001099220
ZNF862
zinc finger protein 862
chr2_-_136875629 6.569 NM_003467
CXCR4
chemokine (C-X-C motif) receptor 4
chr7_+_86781644 6.517 NM_001142326
NM_001142327
DMTF1

cyclin D binding myb-like transcription factor 1

chr3_+_47324329 6.474 NM_025010
KLHL18
kelch-like 18 (Drosophila)
chr8_+_28748030 6.458 NM_024567
HMBOX1
homeobox containing 1
chr1_+_26438267 6.421 NM_001243533
NM_152835
PDIK1L

PDLIM1 interacting kinase 1 like

chr7_-_44924946 6.417 NM_033224
PURB
purine-rich element binding protein B
chr2_-_157189040 6.385 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr2_-_86116016 6.351 NM_003896
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr17_-_43568124 6.344 NM_014798
PLEKHM1
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr7_-_22396511 6.325 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr2_-_235405692 6.303 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr11_+_61520000 6.260 NM_001127392
C11orf9
chromosome 11 open reading frame 9
chr13_+_22245083 6.253 NM_002010
FGF9
fibroblast growth factor 9 (glia-activating factor)
chr2_-_136873740 6.243 NM_001008540
CXCR4
chemokine (C-X-C motif) receptor 4
chr6_+_126111782 6.216 NM_001122842
NM_001199621
NM_181782
NCOA7


nuclear receptor coactivator 7


chr4_-_176923572 6.197 NM_005277
NM_201592
GPM6A

glycoprotein M6A

chr6_+_126102278 6.191 NM_001199619
NM_001199620
NCOA7

nuclear receptor coactivator 7

chr8_-_18871163 6.186 NM_015310
PSD3
pleckstrin and Sec7 domain containing 3
chr4_+_154125589 6.075 NM_015271
TRIM2
tripartite motif containing 2
chr5_-_174871162 5.982 NM_000794
DRD1
dopamine receptor D1
chr2_+_74273449 5.924 NM_144993
TET3
tet methylcytosine dioxygenase 3
chr4_+_154074269 5.920 NM_001130067
TRIM2
tripartite motif containing 2
chr16_-_4323000 5.873 NM_003223
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr11_+_63606346 5.865 NM_001039469
NM_001163296
NM_001163297
NM_004954
MARK2



MAP/microtubule affinity-regulating kinase 2



chr6_-_167040700 5.855 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr8_-_134584012 5.818 NM_003033
NM_173344
ST3GAL1

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

chr17_-_40897025 5.799 NM_001991
EZH1
enhancer of zeste homolog 1 (Drosophila)
chrX_+_16737661 5.774 NM_032796
SYAP1
synapse associated protein 1
chr2_+_16080639 5.773 NM_005378
MYCN
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr13_-_26795927 5.738 NM_183043
RNF6
ring finger protein (C3H2C3 type) 6
chr17_-_66287256 5.643 NM_001174166
NM_004694
SLC16A6

solute carrier family 16, member 6 (monocarboxylic acid transporter 7)

chr16_+_19125243 5.643 NM_001034841
ITPRIPL2
inositol 1,4,5-trisphosphate receptor interacting protein-like 2
chr1_+_183605207 5.631 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr20_-_47894591 5.566 NM_021035
ZNFX1
zinc finger, NFX1-type containing 1
chr3_-_171177851 5.558 NM_001161560
NM_001161561
NM_001161562
NM_001161563
NM_001161564
NM_001161565
NM_001161566
NM_015028
TNIK







TRAF2 and NCK interacting kinase







chr9_-_130742803 5.546 NM_001035254
FAM102A
family with sequence similarity 102, member A
chr15_-_77712436 5.483 NM_024776
PEAK1
NKF3 kinase family member
chr11_+_61522860 5.432 NM_013279
C11orf9
chromosome 11 open reading frame 9
chr12_+_32654976 5.403 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr9_-_23826062 5.402 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr2_-_213403280 5.375 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr1_+_3569098 5.324 NM_001204184
NM_001204185
NM_001204186
NM_001204187
NM_001204188
NM_005427
TP73





tumor protein p73





chr5_+_49962771 5.323 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr9_-_23821477 5.281 NM_001171197
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr2_-_2334887 5.228 NM_015025
MYT1L
myelin transcription factor 1-like
chr6_+_126240369 5.222 NM_001199622
NCOA7
nuclear receptor coactivator 7
chr4_+_156588811 5.183 NM_001130684
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr11_+_73019662 5.136 NM_014786
ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17
chr19_+_38397841 5.102 NM_015073
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr4_-_109087876 5.034 NM_001166119
LEF1
lymphoid enhancer-binding factor 1
chr7_+_100136784 4.988 NM_006076
AGFG2
ArfGAP with FG repeats 2
chr8_-_17579729 4.971 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr12_+_132379262 4.963 NM_003565
ULK1
unc-51-like kinase 1 (C. elegans)
chr20_-_36156082 4.947 NM_001167822
NM_001167821
BLCAP

bladder cancer associated protein

chr2_+_97481977 4.930 NM_017623
NM_199078
CNNM3

cyclin M3

chr8_+_42752019 4.927 NM_032410
HOOK3
hook homolog 3 (Drosophila)
chr15_-_61521478 4.924 NM_134261
RORA
RAR-related orphan receptor A
chr8_-_17658385 4.915 NM_001001924
NM_001001925
MTUS1

microtubule associated tumor suppressor 1

chr7_-_99756275 4.915 NM_018275
C7orf43
chromosome 7 open reading frame 43
chr7_-_5821250 4.913 NM_207111
NM_207116
RNF216

ring finger protein 216

chr13_+_39612440 4.892 NM_001012754
NM_001017370
NHLRC3

NHL repeat containing 3

chr1_-_226076766 4.885 NM_020997
LEFTY1
left-right determination factor 1
chr19_+_15218141 4.863 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr15_+_92937104 4.852 NM_006011
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr8_-_18666295 4.806 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chrX_+_133507299 4.769 NM_001015877
NM_032335
NM_032458
PHF6


PHD finger protein 6


chr11_+_120894756 4.756 NM_001130047
NM_152715
TBCEL

tubulin folding cofactor E-like

chr17_+_42264300 4.753 NM_001076674
NM_024107
TMUB2

transmembrane and ubiquitin-like domain containing 2

chr5_-_1882764 4.751 NM_016358
IRX4
iroquois homeobox 4
chr10_+_1102741 4.702 NM_014023
WDR37
WD repeat domain 37
chr2_+_70142152 4.661 NM_001202513
NM_001202514
NM_002357
MXD1


MAX dimerization protein 1


chr12_+_51632507 4.651 NM_001136264
NM_001136266
NM_001136267
NM_001136268
NM_001136269
NM_014764
DAZAP2





DAZ associated protein 2





chr11_-_62494785 4.643 NM_001079559
HNRNPUL2-BSCL2
HNRNPUL2
HNRNPUL2-BSCL2 readthrough
heterogeneous nuclear ribonucleoprotein U-like 2
chr6_+_108487214 4.619 NM_003269
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr2_-_214016332 4.608 NM_001079526
IKZF2
IKAROS family zinc finger 2 (Helios)
chr4_+_6271558 4.606 NM_001145853
NM_006005
WFS1

Wolfram syndrome 1 (wolframin)

chr7_+_94536926 4.606 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory subunit 9A

chr19_+_14016955 4.602 NM_017721
CC2D1A
coiled-coil and C2 domain containing 1A
chr20_-_35724401 4.590 NM_002895
NM_183404
RBL1

retinoblastoma-like 1 (p107)

chr12_+_72666462 4.586 NM_013381
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr10_-_90342947 4.565 NM_001031709
NM_018363
RNLS

renalase, FAD-dependent amine oxidase

chr8_-_82024277 4.560 NM_018440
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr1_+_6845381 4.556 NM_001195563
NM_001242701
NM_015215
CAMTA1


calmodulin binding transcription activator 1


chr5_+_49961732 4.528 NM_001178055
PARP8
poly (ADP-ribose) polymerase family, member 8
chr20_-_36156282 4.512 NM_001167820
NM_006698
BLCAP

bladder cancer associated protein

chr17_+_42264573 4.477 NM_177441
TMUB2
transmembrane and ubiquitin-like domain containing 2
chr12_-_56652118 4.436 NM_173595
ANKRD52
ankyrin repeat domain 52
chr9_-_130712866 4.417 NM_203305
FAM102A
family with sequence similarity 102, member A
chr3_-_123603144 4.404 NM_053025
NM_053026
NM_053027
NM_053028
MYLK



myosin light chain kinase



chr3_-_187452669 4.339 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr13_-_27334777 4.335 NM_005288
GPR12
G protein-coupled receptor 12
chr10_+_115803805 4.318 NM_000684
ADRB1
adrenergic, beta-1-, receptor
chr10_-_81205091 4.308 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr10_-_91295310 4.271 NM_213606
SLC16A12
solute carrier family 16, member 12 (monocarboxylic acid transporter 12)
chr13_-_20735182 4.244 NM_021954
GJA3
gap junction protein, alpha 3, 46kDa
chr15_-_83953465 4.215 NM_001717
BNC1
basonuclin 1
chr3_+_14989076 4.199 NM_003298
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr9_-_135996287 4.153 NM_006266
RALGDS
ral guanine nucleotide dissociation stimulator
chr9_-_10612722 4.122 NM_002839
PTPRD
protein tyrosine phosphatase, receptor type, D
chr18_+_42260774 4.118 NM_015559
SETBP1
SET binding protein 1
chr14_-_92506284 4.103 NM_004239
TRIP11
thyroid hormone receptor interactor 11
chr17_+_5185551 4.101 NM_001083585
NM_004703
RABEP1

rabaptin, RAB GTPase binding effector protein 1

chr12_-_21927614 4.085 NM_004982
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr12_+_112563293 4.083 NM_001143906
NM_006700
TRAFD1

TRAF-type zinc finger domain containing 1

chr15_+_44580870 4.064 NM_138423
NM_177974
CASC4

cancer susceptibility candidate 4

chr5_+_133706869 4.056 NM_003337
UBE2B
ubiquitin-conjugating enzyme E2B
chr10_-_23003443 4.036 NM_005028
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr8_+_28351694 4.018 NM_017412
NM_145866
FZD3

frizzled family receptor 3

chr14_+_33408458 4.015 NM_001164749
NM_001165893
NM_022123
NM_173159
NPAS3



neuronal PAS domain protein 3



chr4_-_170947428 4.003 NM_021647
MFAP3L
microfibrillar-associated protein 3-like
chr13_-_26795821 3.998 NM_183044
RNF6
ring finger protein (C3H2C3 type) 6
chr2_-_68479481 3.992 NM_000945
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr4_+_126237566 3.964 NM_024582
FAT4
FAT tumor suppressor homolog 4 (Drosophila)
chr3_-_187454247 3.884 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr6_+_1390068 3.883 NM_001452
FOXF2
forkhead box F2
chr19_-_37019169 3.851 NM_001012756
NM_001166036
NM_001166037
NM_001166038
ZNF260



zinc finger protein 260



chr11_+_35684342 3.850 NM_017583
TRIM44
tripartite motif containing 44
chr1_+_245318245 3.837 NM_018012
KIF26B
kinesin family member 26B
chr19_-_45004482 3.837 NM_013256
ZNF180
zinc finger protein 180
chr21_-_32931289 3.823 NM_003253
TIAM1
T-cell lymphoma invasion and metastasis 1
chr22_+_33196801 3.819 NM_000362
TIMP3
TIMP metallopeptidase inhibitor 3
chr2_-_145090038 3.809 NM_001164629
GTDC1
glycosyltransferase-like domain containing 1
chr2_-_86094792 3.804 NM_001042437
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr3_-_169899519 3.802 NM_024947
PHC3
polyhomeotic homolog 3 (Drosophila)
chr20_+_46130600 3.766 NM_001174087
NM_001174088
NM_006534
NM_181659
NCOA3



nuclear receptor coactivator 3



chr17_+_4736612 3.729 NM_001024937
NM_015716
NM_153827
NM_170663
MINK1



misshapen-like kinase 1



chr12_+_122459791 3.725 NM_001024808
NM_020993
BCL7A

B-cell CLL/lymphoma 7A

chr5_+_172483285 3.695 NM_001168393
NM_001168394
NM_153607
C5orf41


chromosome 5 open reading frame 41


chr17_-_2304217 3.692 NM_020310
MNT
MAX binding protein
chr1_+_84609941 3.656 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr5_+_56110899 3.595 NM_005921
MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr9_-_37465384 3.593 NM_014872
ZBTB5
zinc finger and BTB domain containing 5
chr9_-_36400817 3.575 NM_194328
NM_194332
RNF38

ring finger protein 38

chr3_+_20081523 3.536 NM_003884
KAT2B
K(lysine) acetyltransferase 2B
chr5_+_112043188 3.523 NM_001127511
APC
adenomatous polyposis coli
chr4_+_156587861 3.492 NM_000856
NM_001130682
NM_001130686
NM_001130687
NM_001130683
NM_001130685
GUCY1A3





guanylate cyclase 1, soluble, alpha 3





chr11_+_129245834 3.480 NM_003658
BARX2
BARX homeobox 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.69 1.70e-09 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.75 5.94e-09 GO:0006351 transcription, DNA-dependent
2.87 7.70e-09 GO:0051173 positive regulation of nitrogen compound metabolic process
2.90 8.18e-09 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.12 1.24e-08 GO:0045893 positive regulation of transcription, DNA-dependent
1.95 1.46e-08 GO:0051252 regulation of RNA metabolic process
2.25 1.53e-08 GO:0007399 nervous system development
1.97 1.91e-08 GO:0006355 regulation of transcription, DNA-dependent
3.45 2.64e-08 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.71 2.77e-08 GO:0007275 multicellular organismal development
2.97 3.97e-08 GO:0051254 positive regulation of RNA metabolic process
1.68 5.16e-08 GO:0031323 regulation of cellular metabolic process
1.83 5.37e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.94 5.57e-08 GO:0010628 positive regulation of gene expression
1.81 7.69e-08 GO:0051171 regulation of nitrogen compound metabolic process
2.67 1.06e-07 GO:0031328 positive regulation of cellular biosynthetic process
1.70 1.42e-07 GO:0060255 regulation of macromolecule metabolic process
2.63 1.98e-07 GO:0009891 positive regulation of biosynthetic process
1.40 2.67e-07 GO:0050794 regulation of cellular process
1.85 3.19e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.66 3.28e-07 GO:0080090 regulation of primary metabolic process
1.37 3.40e-07 GO:0050789 regulation of biological process
2.48 3.41e-07 GO:0032774 RNA biosynthetic process
2.73 4.83e-07 GO:0010557 positive regulation of macromolecule biosynthetic process
1.75 5.33e-07 GO:0048731 system development
1.82 6.76e-07 GO:0010556 regulation of macromolecule biosynthetic process
1.62 7.59e-07 GO:0032502 developmental process
1.80 8.26e-07 GO:0010468 regulation of gene expression
1.59 1.03e-06 GO:0019222 regulation of metabolic process
1.77 1.13e-06 GO:0031326 regulation of cellular biosynthetic process
1.34 1.28e-06 GO:0065007 biological regulation
1.75 2.17e-06 GO:0009889 regulation of biosynthetic process
2.99 3.04e-06 GO:0045892 negative regulation of transcription, DNA-dependent
2.93 5.35e-06 GO:0051253 negative regulation of RNA metabolic process
1.66 5.78e-06 GO:0048856 anatomical structure development
2.12 1.83e-05 GO:0009893 positive regulation of metabolic process
2.73 2.32e-05 GO:0010629 negative regulation of gene expression
3.07 3.24e-05 GO:0032583 regulation of gene-specific transcription
2.64 5.84e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.59 6.64e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
2.13 6.75e-05 GO:0010604 positive regulation of macromolecule metabolic process
2.62 1.03e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.18 1.19e-04 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
2.59 1.43e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.77 1.74e-04 GO:0030154 cell differentiation
2.07 1.79e-04 GO:0031325 positive regulation of cellular metabolic process
2.48 2.02e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.74 2.88e-04 GO:0048869 cellular developmental process
2.43 3.49e-04 GO:0009890 negative regulation of biosynthetic process
1.62 5.18e-04 GO:0048518 positive regulation of biological process
1.66 6.12e-04 GO:0048522 positive regulation of cellular process
2.05 2.01e-03 GO:0042981 regulation of apoptosis
2.17 2.56e-03 GO:0016310 phosphorylation
2.03 2.57e-03 GO:0043067 regulation of programmed cell death
1.47 2.81e-03 GO:0023052 signaling
6.69 2.95e-03 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
1.49 3.55e-03 GO:0007165 signal transduction
2.09 3.90e-03 GO:0010605 negative regulation of macromolecule metabolic process
2.09 3.90e-03 GO:0022008 neurogenesis
2.00 4.02e-03 GO:0010941 regulation of cell death
2.23 4.11e-03 GO:0006468 protein phosphorylation
1.71 5.20e-03 GO:0010467 gene expression
2.73 6.30e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.07 6.79e-03 GO:0031324 negative regulation of cellular metabolic process
1.39 9.01e-03 GO:0044260 cellular macromolecule metabolic process
3.54 1.02e-02 GO:0032582 negative regulation of gene-specific transcription
2.07 1.09e-02 GO:0048699 generation of neurons
1.82 1.13e-02 GO:0035556 intracellular signal transduction
1.97 1.14e-02 GO:0006793 phosphorus metabolic process
1.97 1.14e-02 GO:0006796 phosphate metabolic process
1.98 1.29e-02 GO:0009892 negative regulation of metabolic process
1.67 1.68e-02 GO:0006464 protein modification process
2.67 2.07e-02 GO:0051056 regulation of small GTPase mediated signal transduction
2.40 2.17e-02 GO:0043065 positive regulation of apoptosis
2.38 2.45e-02 GO:0043068 positive regulation of programmed cell death
1.33 2.49e-02 GO:0032501 multicellular organismal process
1.67 2.73e-02 GO:0016070 RNA metabolic process
1.69 2.84e-02 GO:0034645 cellular macromolecule biosynthetic process
2.34 3.36e-02 GO:0010942 positive regulation of cell death
1.34 3.57e-02 GO:0043170 macromolecule metabolic process
1.62 4.13e-02 GO:0048513 organ development
1.67 4.13e-02 GO:0009059 macromolecule biosynthetic process
1.67 4.99e-02 GO:0023051 regulation of signaling

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.48 1.92e-08 GO:0005634 nucleus
2.19 1.01e-03 GO:0044451 nucleoplasm part
1.83 1.18e-03 GO:0005654 nucleoplasm
1.67 2.15e-03 GO:0031981 nuclear lumen
1.18 6.70e-03 GO:0043226 organelle
1.18 8.57e-03 GO:0043229 intracellular organelle
1.14 1.21e-02 GO:0005622 intracellular
2.83 1.94e-02 GO:0005667 transcription factor complex
1.07 2.93e-02 GO:0044464 cell part
1.07 2.97e-02 GO:0005623 cell
1.51 3.28e-02 GO:0044428 nuclear part
1.18 4.26e-02 GO:0043227 membrane-bounded organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.96 2.88e-14 GO:0001071 nucleic acid binding transcription factor activity
2.96 2.88e-14 GO:0003700 sequence-specific DNA binding transcription factor activity
2.00 4.91e-11 GO:0003677 DNA binding
3.03 5.93e-10 GO:0043565 sequence-specific DNA binding
2.56 1.21e-09 GO:0030528 transcription regulator activity
9.72 1.46e-07 GO:0003707 steroid hormone receptor activity
1.65 2.13e-07 GO:0003676 nucleic acid binding
9.18 3.16e-07 GO:0004879 ligand-dependent nuclear receptor activity
3.34 1.55e-05 GO:0016563 transcription activator activity
1.49 5.31e-05 GO:0046872 metal ion binding
1.47 1.06e-04 GO:0043169 cation binding
1.47 1.23e-04 GO:0043167 ion binding
1.69 2.74e-04 GO:0008270 zinc ion binding
3.05 4.53e-04 GO:0016564 transcription repressor activity
2.21 8.45e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
5.03 1.43e-03 GO:0005088 Ras guanyl-nucleotide exchange factor activity
1.15 1.65e-03 GO:0005488 binding
2.11 1.98e-03 GO:0016301 kinase activity
2.55 2.09e-03 GO:0004674 protein serine/threonine kinase activity
3.40 2.14e-03 GO:0000975 regulatory region DNA binding
3.40 2.14e-03 GO:0001067 regulatory region nucleic acid binding
3.40 2.14e-03 GO:0044212 transcription regulatory region DNA binding
2.94 2.20e-03 GO:0005083 small GTPase regulator activity
1.57 2.46e-03 GO:0046914 transition metal ion binding
2.23 3.87e-03 GO:0004672 protein kinase activity
3.60 6.32e-03 GO:0005085 guanyl-nucleotide exchange factor activity
1.91 1.28e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
3.15 1.77e-02 GO:0010843 promoter binding
2.67 2.32e-02 GO:0008134 transcription factor binding
2.23 4.05e-02 GO:0030695 GTPase regulator activity
13.86 4.16e-02 GO:0046875 ephrin receptor binding