Motif ID: ACAGUAU

Z-value: 1.121


Mature miRNA associated with seed ACAGUAU:

NamemiRBase Accession
hsa-miR-144 MIMAT0000436



Activity profile for motif ACAGUAU.

activity profile for motif ACAGUAU


Sorted Z-values histogram for motif ACAGUAU

Sorted Z-values for motif ACAGUAU



Network of associatons between targets according to the STRING database.



First level regulatory network of ACAGUAU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_195808958 34.292 NM_003234
TFRC
transferrin receptor (p90, CD71)
chr3_-_195808997 33.766 NM_001128148
TFRC
transferrin receptor (p90, CD71)
chr17_-_38574042 24.541 NM_001067
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr12_-_31479120 23.252 NM_001135811
NM_021238
NM_001135812
FAM60A


family with sequence similarity 60, member A


chr20_-_32899607 17.845 NM_001161766
AHCY
adenosylhomocysteinase
chr11_+_16760147 17.167 NM_014267
C11orf58
chromosome 11 open reading frame 58
chr20_-_32891075 16.666 NM_000687
AHCY
adenosylhomocysteinase
chr3_+_151985828 16.413 NM_021038
NM_207292
MBNL1

muscleblind-like (Drosophila)

chr1_-_225616556 16.404 NM_194442
LBR
lamin B receptor
chr1_-_95392501 16.018 NM_001839
CNN3
calponin 3, acidic
chr4_-_139163222 15.884 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr3_+_150321065 15.812 NM_016275
SELT
selenoprotein T
chr9_+_112542496 15.179 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr2_-_227663454 14.717 NM_005544
IRS1
insulin receptor substrate 1
chr3_+_152017193 14.318 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
MBNL1




muscleblind-like (Drosophila)




chr18_+_3453771 14.234 NM_173211
TGIF1
TGFB-induced factor homeobox 1
chr1_+_167298280 14.135 NM_001198783
POU2F1
POU class 2 homeobox 1
chr18_+_3449972 14.069 NM_173209
NM_173208
NM_003244
TGIF1


TGFB-induced factor homeobox 1


chr1_-_225615787 13.948 NM_002296
LBR
lamin B receptor
chr18_+_3447607 13.873 NM_173207
TGIF1
TGFB-induced factor homeobox 1
chr11_-_10830581 13.793 NM_001042559
NM_001418
EIF4G2

eukaryotic translation initiation factor 4 gamma, 2

chr18_+_3412071 13.678 NM_174886
TGIF1
TGFB-induced factor homeobox 1
chrX_-_108976509 13.626 NM_004458
NM_022977
ACSL4

acyl-CoA synthetase long-chain family member 4

chr6_+_64281910 13.479 NM_003463
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr1_-_68299047 13.456 NM_018841
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr5_+_72112417 13.336 NM_002270
TNPO1
transportin 1
chr18_+_3451589 13.254 NM_170695
NM_173210
TGIF1

TGFB-induced factor homeobox 1

chr17_-_4269814 12.918 NM_003342
UBE2G1
ubiquitin-conjugating enzyme E2G 1
chr2_-_175113284 12.402 NM_001011708
NM_013341
OLA1

Obg-like ATPase 1

chr7_-_131241321 12.272 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr1_+_165796652 12.073 NM_012474
UCK2
uridine-cytidine kinase 2
chr14_-_21737506 11.869 NM_001077442
NM_001077443
NM_004500
NM_031314
HNRNPC



heterogeneous nuclear ribonucleoprotein C (C1/C2)



chr6_-_86352635 11.786 NM_001159673
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr16_-_12010518 11.518 NM_001130007
GSPT1
G1 to S phase transition 1
chr6_-_86352564 11.492 NM_001159674
NM_001253771
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr15_+_101420004 11.428 NM_000693
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr12_-_111180730 11.284 NM_001244974
NM_002710
PPP1CC

protein phosphatase 1, catalytic subunit, gamma isozyme

chr4_+_174089889 11.025 NM_017423
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr6_-_86351156 10.806 NM_001159675
NM_001159676
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr7_+_116139619 10.741 NM_001206747
NM_001233
NM_198212
CAV2


caveolin 2


chr16_-_12009804 10.614 NM_001130006
NM_002094
GSPT1

G1 to S phase transition 1

chr5_+_72143929 10.469 NM_153188
TNPO1
transportin 1
chr5_-_127873734 10.431 NM_001999
FBN2
fibrillin 2
chr20_-_52199635 10.426 NM_006526
ZNF217
zinc finger protein 217
chr8_-_42065193 10.278 NM_000930
NM_033011
PLAT

plasminogen activator, tissue

chr15_-_49447765 10.210 NM_001143887
NM_004236
COPS2

COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)

chr1_+_955468 10.193 NM_198576
AGRN
agrin
chr8_+_126442557 10.171 NM_025195
TRIB1
tribbles homolog 1 (Drosophila)
chr9_+_112887780 10.157 NM_001136562
AKAP2
A kinase (PRKA) anchor protein 2
chr7_+_116140097 10.039 NM_001206748
CAV2
caveolin 2
chr12_+_50135591 9.871 NM_001098576
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr4_+_144434555 9.829 NM_003601
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr7_-_27213873 9.742 NM_018951
HOXA10
homeobox A10
chr2_-_216300770 9.724 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr9_+_112810877 9.696 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr15_+_96869156 9.407 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chrX_-_109683457 9.242 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr6_+_114178516 9.227 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr21_-_43346780 9.100 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr19_+_34663311 9.038 NM_001114093
NM_015578
LSM14A

LSM14A, SCD6 homolog A (S. cerevisiae)

chr3_+_30647901 8.942 NM_001024847
NM_003242
TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

chr17_-_77813049 8.921 NM_003655
CBX4
chromobox homolog 4
chr1_+_26798901 8.893 NM_005517
HMGN2
high mobility group nucleosomal binding domain 2
chr9_+_118916069 8.862 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr1_+_27022521 8.688 NM_006015
NM_139135
ARID1A

AT rich interactive domain 1A (SWI-like)

chr3_-_125094003 8.437 NM_021964
ZNF148
zinc finger protein 148
chr10_+_5488521 8.382 NM_005863
NET1
neuroepithelial cell transforming 1
chr7_+_101460881 8.366 NM_181552
CUX1
cut-like homeobox 1
chr5_-_142783975 8.351 NM_001018076
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr10_+_89623091 8.331 NM_000314
PTEN
phosphatase and tensin homolog
chr6_+_136172802 8.331 NM_018945
PDE7B
phosphodiesterase 7B
chrX_+_118714297 8.128 NM_181777
UBE2A
ubiquitin-conjugating enzyme E2A
chr13_-_110959441 8.118 NM_001845
COL4A1
collagen, type IV, alpha 1
chr12_-_54070511 8.070 NM_001002031
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr21_-_43373938 8.053 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr12_+_4430346 7.992 NM_020375
C12orf5
chromosome 12 open reading frame 5
chr4_-_103748649 7.847 NM_181887
NM_181891
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr18_+_33234532 7.824 NM_020474
GALNT1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chr4_-_103748254 7.632 NM_181892
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr9_+_128510477 7.267 NM_001134778
PBX3
pre-B-cell leukemia homeobox 3
chr15_-_48937795 7.049 NM_000138
FBN1
fibrillin 1
chr5_+_65440662 6.983 NM_139168
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr4_-_103748966 6.940 NM_003340
NM_181886
NM_181888
NM_181889
UBE2D3



ubiquitin-conjugating enzyme E2D 3



chr2_+_85198176 6.920 NM_020122
KCMF1
potassium channel modulatory factor 1
chr2_+_201676260 6.889 NM_001207067
NM_014670
BZW1

basic leucine zipper and W2 domains 1

chrX_-_109561314 6.850 NM_001025580
NM_015365
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr12_+_13349601 6.825 NM_001423
EMP1
epithelial membrane protein 1
chr5_+_65440004 6.737 NM_001077199
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr12_-_54070108 6.729 NM_005176
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr10_+_94352809 6.626 NM_004523
KIF11
kinesin family member 11
chr14_-_95599794 6.559 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr6_-_86352982 6.515 NM_001159677
NM_006372
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr13_+_41363546 6.446 NM_014252
SLC25A15
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
chr7_+_115863004 6.433 NM_152829
TES
testis derived transcript (3 LIM domains)
chr8_+_26150731 6.307 NM_001177591
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr6_-_24719286 6.296 NM_030939
C6orf62
chromosome 6 open reading frame 62
chr8_+_26149004 6.265 NM_002717
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr17_+_30677138 6.128 NM_001032293
NM_001098507
NM_003457
ZNF207


zinc finger protein 207


chr15_+_96876568 6.056 NM_001145157
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr10_-_126849066 6.046 NM_001329
CTBP2
C-terminal binding protein 2
chr1_-_235490801 6.012 NM_001206794
ARID4B
AT rich interactive domain 4B (RBP1-like)
chr13_-_50367027 5.924 NM_002267
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr2_-_37899227 5.923 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr10_-_43892697 5.843 NM_001098207
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr12_+_50135292 5.837 NM_003217
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr2_+_198380294 5.833 NM_199482
MOB4
MOB family member 4, phocein
chr3_+_141043054 5.821 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr10_-_43903220 5.809 NM_001098206
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr10_+_5454516 5.805 NM_001047160
NET1
neuroepithelial cell transforming 1
chr10_-_43892160 5.742 NM_001098208
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr16_-_88851371 5.732 NM_001142864
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr16_-_65155881 5.709 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr7_-_93633527 5.687 NM_005868
BET1
blocked early in transport 1 homolog (S. cerevisiae)
chr1_+_167189948 5.682 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr8_-_12973752 5.659 NM_001164271
DLC1
deleted in liver cancer 1
chr9_+_128509616 5.641 NM_006195
PBX3
pre-B-cell leukemia homeobox 3
chr1_-_245027808 5.612 NM_004501
NM_031844
HNRNPU

heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)

chr15_-_37391596 5.611 NM_172316
MEIS2
Meis homeobox 2
chr1_-_225840660 5.595 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr3_+_69812620 5.589 NM_001184967
MITF
microphthalmia-associated transcription factor
chr1_-_31538553 5.578 NM_001020658
NM_014676
PUM1

pumilio homolog 1 (Drosophila)

chr2_-_37544165 5.578 NM_005813
PRKD3
protein kinase D3
chr1_+_116184573 5.555 NM_001172411
NM_138959
VANGL1

vang-like 1 (van gogh, Drosophila)

chr7_-_148580600 5.551 NM_001203249
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr6_+_160390128 5.492 NM_000876
IGF2R
insulin-like growth factor 2 receptor
chr1_+_2985730 5.477 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr7_+_115850546 5.463 NM_015641
TES
testis derived transcript (3 LIM domains)
chr2_+_118572254 5.450 NM_006773
DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr7_-_105752974 5.443 NM_006754
SYPL1
synaptophysin-like 1
chr2_-_43453737 5.432 NM_006887
ZFP36L2
zinc finger protein 36, C3H type-like 2
chr5_+_154092461 5.360 NM_015315
LARP1
La ribonucleoprotein domain family, member 1
chr3_+_107241782 5.357 NM_001142568
NM_020235
BBX

bobby sox homolog (Drosophila)

chr8_+_125486949 5.287 NM_007218
RNF139
ring finger protein 139
chr3_-_124774735 5.274 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chrX_+_118708476 5.244 NM_003336
NM_181762
UBE2A

ubiquitin-conjugating enzyme E2A

chr3_-_81810914 5.223 NM_000158
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr14_+_23789396 5.215 NM_004643
PABPN1
poly(A) binding protein, nuclear 1
chr12_+_104359557 5.184 NM_003211
TDG
thymine-DNA glycosylase
chr3_-_149375584 5.180 NM_001168280
NM_015472
WWTR1

WW domain containing transcription regulator 1

chr1_+_87170222 5.168 NM_001206651
NM_001206652
NM_001206653
NM_016009
SH3GLB1



SH3-domain GRB2-like endophilin B1



chr16_-_84651639 5.153 NM_021149
COTL1
coactosin-like 1 (Dictyostelium)
chr3_-_47823386 5.145 NM_003074
SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr3_+_69812961 4.996 NM_006722
MITF
microphthalmia-associated transcription factor
chr5_+_176560056 4.984 NM_172349
NSD1
nuclear receptor binding SET domain protein 1
chr5_-_142815076 4.977 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr7_-_105752718 4.975 NM_182715
SYPL1
synaptophysin-like 1
chr1_+_116185249 4.942 NM_001172412
VANGL1
vang-like 1 (van gogh, Drosophila)
chr14_+_103801160 4.901 NM_183004
EIF5
eukaryotic translation initiation factor 5
chr20_+_61427804 4.891 NM_018270
C20orf20
chromosome 20 open reading frame 20
chr10_-_126716452 4.859 NM_022802
CTBP2
C-terminal binding protein 2
chr6_+_7107986 4.853 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr2_+_74056095 4.776 NM_006463
NM_213622
STAMBP

STAM binding protein

chr12_-_56652118 4.760 NM_173595
ANKRD52
ankyrin repeat domain 52
chr2_+_208394615 4.752 NM_004379
NM_134442
CREB1

cAMP responsive element binding protein 1

chr15_+_96875793 4.734 NM_001145156
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr3_-_149421059 4.722 NM_001168278
WWTR1
WW domain containing transcription regulator 1
chr17_+_48133331 4.692 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr10_+_112257624 4.619 NM_004419
DUSP5
dual specificity phosphatase 5
chr1_-_235491494 4.600 NM_016374
NM_031371
ARID4B

AT rich interactive domain 4B (RBP1-like)

chr11_-_27494232 4.558 NM_018490
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr6_-_82462374 4.551 NM_017633
FAM46A
family with sequence similarity 46, member A
chr20_-_48729664 4.537 NM_001032288
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr1_-_93646245 4.530 NM_001167830
NM_016040
TMED5

transmembrane emp24 protein transport domain containing 5

chr4_-_71705188 4.512 NM_001098477
GRSF1
G-rich RNA sequence binding factor 1
chr15_-_37390372 4.467 NM_172315
MEIS2
Meis homeobox 2
chr10_-_43904306 4.428 NM_001098205
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr10_+_17686123 4.414 NM_003473
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr11_+_9685624 4.366 NM_015055
SWAP70
SWAP switching B-cell complex 70kDa subunit
chr16_-_87525317 4.333 NM_015144
ZCCHC14
zinc finger, CCHC domain containing 14
chr4_-_103790002 4.331 NM_181893
NM_181890
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr15_+_77223942 4.319 NM_002902
RCN2
reticulocalbin 2, EF-hand calcium binding domain
chr14_-_64010063 4.306 NM_006246
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr21_-_36421586 4.252 NM_001754
RUNX1
runt-related transcription factor 1
chr7_+_116312412 4.227 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr2_+_74056042 4.184 NM_201647
STAMBP
STAM binding protein
chr10_+_95256348 4.167 NM_001127182
NM_018131
CEP55

centrosomal protein 55kDa

chr5_-_126366439 4.162 NM_178450
MARCH3
membrane-associated ring finger (C3HC4) 3
chr3_+_152880024 4.161 NM_002886
RAP2B
RAP2B, member of RAS oncogene family
chrX_+_40944858 4.151 NM_001039590
NM_001039591
USP9X

ubiquitin specific peptidase 9, X-linked

chr1_+_110091185 4.131 NM_006496
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr20_-_48732479 4.123 NM_022442
NM_021988
NM_199144
UBE2V1


ubiquitin-conjugating enzyme E2 variant 1


chrX_-_99891690 4.118 NM_003270
TSPAN6
tetraspanin 6
chr18_+_8717368 4.111 NM_015210
CCDC165
coiled-coil domain containing 165
chr15_+_39873276 4.110 NM_003246
THBS1
thrombospondin 1
chr14_+_73525187 4.097 NM_021239
RBM25
RNA binding motif protein 25
chr12_-_76425375 4.088 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr21_-_46238040 4.077 NM_006936
SUMO3
SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
chr5_-_83016850 4.042 NM_001884
HAPLN1
hyaluronan and proteoglycan link protein 1
chr1_+_153606457 3.970 NM_001206612
NM_001244664
NM_015607
CHTOP


chromatin target of PRMT1


chr10_-_43904598 3.926 NM_004966
NM_001098204
HNRNPF

heterogeneous nuclear ribonucleoprotein F

chr2_-_178128527 3.911 NM_001145412
NM_001145413
NFE2L2

nuclear factor (erythroid-derived 2)-like 2

chr8_-_12990731 3.910 NM_006094
DLC1
deleted in liver cancer 1
chr2_-_65357249 3.879 NM_004161
NM_015543
RAB1A

RAB1A, member RAS oncogene family

chr3_+_69788562 3.857 NM_198159
MITF
microphthalmia-associated transcription factor
chr9_-_107690526 3.847 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr3_-_136471186 3.798 NM_005862
STAG1
stromal antigen 1
chr11_+_107879407 3.784 NM_003478
CUL5
cullin 5
chr11_+_11862955 3.783 NM_017944
USP47
ubiquitin specific peptidase 47
chr7_-_47621741 3.741 NM_022748
TNS3
tensin 3
chr2_+_160568973 3.723 NM_022826
MARCH7
membrane-associated ring finger (C3HC4) 7

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.86 2.04e-10 GO:0080090 regulation of primary metabolic process
1.85 2.46e-10 GO:0031323 regulation of cellular metabolic process
1.88 3.17e-10 GO:0060255 regulation of macromolecule metabolic process
1.48 4.26e-09 GO:0050794 regulation of cellular process
1.97 1.65e-08 GO:0010468 regulation of gene expression
1.72 2.96e-08 GO:0019222 regulation of metabolic process
1.42 1.22e-07 GO:0050789 regulation of biological process
1.39 1.36e-07 GO:0065007 biological regulation
1.94 2.94e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.91 5.20e-07 GO:0010556 regulation of macromolecule biosynthetic process
1.60 1.24e-06 GO:0044260 cellular macromolecule metabolic process
1.94 1.52e-06 GO:0051252 regulation of RNA metabolic process
1.83 2.26e-06 GO:0031326 regulation of cellular biosynthetic process
1.23 3.90e-06 GO:0009987 cellular process
1.81 4.09e-06 GO:0009889 regulation of biosynthetic process
2.49 8.08e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.79 1.05e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.89 1.82e-05 GO:0048523 negative regulation of cellular process
1.76 2.27e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.41 4.62e-05 GO:0044237 cellular metabolic process
1.79 1.08e-04 GO:0048519 negative regulation of biological process
2.76 1.45e-04 GO:0045893 positive regulation of transcription, DNA-dependent
1.82 1.49e-04 GO:0006355 regulation of transcription, DNA-dependent
1.47 2.03e-04 GO:0043170 macromolecule metabolic process
2.44 2.15e-04 GO:0009891 positive regulation of biosynthetic process
1.75 2.27e-04 GO:0048522 positive regulation of cellular process
2.65 2.54e-04 GO:0051254 positive regulation of RNA metabolic process
1.56 3.11e-04 GO:0032502 developmental process
2.63 3.22e-04 GO:0010628 positive regulation of gene expression
2.42 3.76e-04 GO:0031328 positive regulation of cellular biosynthetic process
2.52 4.14e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
2.10 4.96e-04 GO:0009893 positive regulation of metabolic process
1.58 6.12e-04 GO:0007275 multicellular organismal development
2.09 1.20e-03 GO:0031325 positive regulation of cellular metabolic process
2.11 1.26e-03 GO:0010604 positive regulation of macromolecule metabolic process
2.40 1.32e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
2.86 1.62e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.40 1.75e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.25 2.31e-03 GO:0031324 negative regulation of cellular metabolic process
1.35 2.97e-03 GO:0044238 primary metabolic process
2.51 4.14e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.62 4.69e-03 GO:0048518 positive regulation of biological process
2.64 5.03e-03 GO:0045892 negative regulation of transcription, DNA-dependent
4.15 5.37e-03 GO:0030900 forebrain development
2.58 7.41e-03 GO:0051253 negative regulation of RNA metabolic process
2.20 7.45e-03 GO:0006351 transcription, DNA-dependent
2.17 7.47e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.75 7.99e-03 GO:0048513 organ development
2.11 8.21e-03 GO:0009892 negative regulation of metabolic process
2.89 8.90e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.38 8.92e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.74 9.41e-03 GO:0043412 macromolecule modification
2.40 1.03e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.29 1.26e-02 GO:0008152 metabolic process
1.75 1.31e-02 GO:0006464 protein modification process
2.33 1.37e-02 GO:0009890 negative regulation of biosynthetic process
2.43 1.62e-02 GO:0010629 negative regulation of gene expression
3.17 2.60e-02 GO:0010608 posttranscriptional regulation of gene expression
1.64 2.77e-02 GO:0090304 nucleic acid metabolic process
1.71 2.81e-02 GO:0010467 gene expression
1.54 3.06e-02 GO:0048731 system development
1.96 3.59e-02 GO:0051246 regulation of protein metabolic process
3.21 3.86e-02 GO:0030334 regulation of cell migration
3.17 4.52e-02 GO:2000145 regulation of cell motility

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.46 2.61e-06 GO:0005634 nucleus
1.21 6.48e-06 GO:0044424 intracellular part
1.20 1.64e-05 GO:0005622 intracellular
1.74 2.78e-04 GO:0044428 nuclear part
1.97 4.39e-04 GO:0005654 nucleoplasm
1.24 1.69e-03 GO:0043231 intracellular membrane-bounded organelle
1.24 1.86e-03 GO:0043227 membrane-bounded organelle
1.72 2.95e-03 GO:0031981 nuclear lumen
1.61 4.40e-03 GO:0031974 membrane-enclosed lumen
1.62 4.56e-03 GO:0043233 organelle lumen
1.32 1.02e-02 GO:0044446 intracellular organelle part
1.19 1.12e-02 GO:0043229 intracellular organelle
1.19 1.30e-02 GO:0043226 organelle
1.58 1.38e-02 GO:0070013 intracellular organelle lumen
1.31 1.44e-02 GO:0044422 organelle part
4.52 4.44e-02 GO:0016585 chromatin remodeling complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.26 4.24e-12 GO:0005488 binding
1.44 1.34e-09 GO:0005515 protein binding
1.76 3.05e-08 GO:0003676 nucleic acid binding
1.76 4.13e-05 GO:0003677 DNA binding
2.26 6.79e-05 GO:0001071 nucleic acid binding transcription factor activity
2.26 6.79e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
2.16 3.36e-04 GO:0030528 transcription regulator activity
3.26 4.33e-04 GO:0016563 transcription activator activity
1.69 4.65e-04 GO:0000166 nucleotide binding
4.41 1.24e-03 GO:0003714 transcription corepressor activity
2.35 1.88e-03 GO:0043565 sequence-specific DNA binding
2.26 2.21e-03 GO:0019899 enzyme binding
1.65 1.82e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.73 1.87e-02 GO:0005524 ATP binding
2.64 1.90e-02 GO:0003712 transcription cofactor activity
2.63 1.98e-02 GO:0000988 protein binding transcription factor activity
2.63 1.98e-02 GO:0000989 transcription factor binding transcription factor activity
1.70 2.80e-02 GO:0032559 adenyl ribonucleotide binding
1.62 2.94e-02 GO:0032553 ribonucleotide binding
1.62 2.94e-02 GO:0032555 purine ribonucleotide binding
1.69 3.23e-02 GO:0030554 adenyl nucleotide binding
1.61 3.45e-02 GO:0017076 purine nucleotide binding
2.74 3.89e-02 GO:0016564 transcription repressor activity