Motif ID: AGCUUAU

Z-value: 0.818


Mature miRNA associated with seed AGCUUAU:

NamemiRBase Accession
hsa-miR-21 MIMAT0000076
hsa-miR-590-5p MIMAT0003258



Activity profile for motif AGCUUAU.

activity profile for motif AGCUUAU


Sorted Z-values histogram for motif AGCUUAU

Sorted Z-values for motif AGCUUAU



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCUUAU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_18466759 10.406 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr7_-_139876718 9.884 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr5_+_67586466 9.402 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr3_-_18480203 8.995 NM_001131010
SATB1
SATB homeobox 1
chr10_+_112631552 8.462 NM_001199492
NM_014456
NM_145341
PDCD4


programmed cell death 4 (neoplastic transformation inhibitor)


chr22_+_33196801 8.019 NM_000362
TIMP3
TIMP metallopeptidase inhibitor 3
chr5_+_67584251 7.174 NM_181524
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr5_+_67511578 7.019 NM_181523
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr5_+_67588395 6.553 NM_001242466
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr22_+_40573879 6.434 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr2_-_64371444 5.539 NM_020651
PELI1
pellino homolog 1 (Drosophila)
chr22_+_40440664 5.182 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr10_-_3827418 5.120 NM_001160124
NM_001160125
NM_001300
KLF6


Kruppel-like factor 6


chr15_-_38856830 5.040 NM_001128602
NM_005739
RASGRP1

RAS guanyl releasing protein 1 (calcium and DAG-regulated)

chr18_-_29523087 4.815 NM_014939
TRAPPC8
trafficking protein particle complex 8
chr4_-_89744154 4.697 NM_001015045
FAM13A
family with sequence similarity 13, member A
chr1_+_203274646 4.692 NM_006763
BTG2
BTG family, member 2
chr3_+_152017193 4.564 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
MBNL1




muscleblind-like (Drosophila)




chr3_+_30647901 4.481 NM_001024847
NM_003242
TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

chr8_+_98881277 4.359 NM_002380
NM_030583
MATN2

matrilin 2

chr4_+_38665587 4.330 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr9_+_36036900 4.066 NM_021111
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
chr10_+_124134093 4.057 NM_001001974
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr3_+_151985828 4.044 NM_021038
NM_207292
MBNL1

muscleblind-like (Drosophila)

chr4_-_89978117 4.028 NM_014883
FAM13A
family with sequence similarity 13, member A
chr17_+_59477169 3.752 NM_005994
TBX2
T-box 2
chrX_+_123095555 3.554 NM_001042750
NM_001042751
NM_006603
STAG2


stromal antigen 2


chr2_-_43453737 3.490 NM_006887
ZFP36L2
zinc finger protein 36, C3H type-like 2
chr8_-_57123858 3.484 NM_001114634
NM_001114635
NM_002655
PLAG1


pleiomorphic adenoma gene 1


chr13_+_73633097 3.217 NM_001730
KLF5
Kruppel-like factor 5 (intestinal)
chr1_+_2160133 3.170 NM_003036
SKI
v-ski sarcoma viral oncogene homolog (avian)
chr12_-_24102563 3.076 NM_006940
SOX5
SRY (sex determining region Y)-box 5
chr6_+_32939371 3.071 NM_001199455
BRD2
bromodomain containing 2
chr4_-_140060601 3.008 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chr12_-_9913415 2.996 NM_001781
CD69
CD69 molecule
chr6_+_32936400 2.989 NM_005104
BRD2
bromodomain containing 2
chr10_+_124145584 2.910 NM_001195608
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr4_+_124317884 2.899 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr3_+_186739643 2.859 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr3_+_186648273 2.834 NM_173216
NM_173217
ST6GAL1

ST6 beta-galactosamide alpha-2,6-sialyltranferase 1

chrX_-_131623994 2.818 NM_001170704
MBNL3
muscleblind-like 3 (Drosophila)
chr10_+_124151818 2.817 NM_021622
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr12_-_24715349 2.800 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chrX_+_123094377 2.671 NM_001042749
STAG2
stromal antigen 2
chr2_+_66662516 2.661 NM_002398
MEIS1
Meis homeobox 1
chr6_+_32938658 2.659 NM_001113182
BRD2
bromodomain containing 2
chr20_-_23030141 2.621 NM_000361
THBD
thrombomodulin
chr10_+_75757847 2.507 NM_003373
NM_014000
VCL

vinculin

chr4_-_140005464 2.471 NM_006874
ELF2
E74-like factor 2 (ets domain transcription factor)
chr7_-_44924946 2.407 NM_033224
PURB
purine-rich element binding protein B
chr12_+_53845884 2.391 NM_001098620
NM_001128911
NM_001128912
NM_001128913
NM_001128914
NM_005016
NM_031989
PCBP2






poly(rC) binding protein 2






chr15_-_33360084 2.389 NM_001103184
FMN1
formin 1
chr6_+_32940860 2.380 NM_001199456
BRD2
bromodomain containing 2
chr6_-_109415514 2.374 NM_014454
SESN1
sestrin 1
chr17_+_21187967 2.338 NM_145109
MAP2K3
mitogen-activated protein kinase kinase 3
chr4_+_124320664 2.301 NM_005841
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr2_+_70314560 2.279 NM_006196
PCBP1
poly(rC) binding protein 1
chr10_+_72163860 2.270 NM_004096
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr7_+_101460881 2.267 NM_181552
CUX1
cut-like homeobox 1
chr6_-_109330190 2.174 NM_001199934
SESN1
sestrin 1
chr6_-_109330752 2.127 NM_001199933
SESN1
sestrin 1
chr16_+_69599868 2.127 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr16_-_4292052 2.090 NM_001098814
SRL
sarcalumenin
chr15_+_40733302 1.999 NM_014952
BAHD1
bromo adjacent homology domain containing 1
chr2_-_60780404 1.997 NM_018014
NM_022893
NM_138559
BCL11A


B-cell CLL/lymphoma 11A (zinc finger protein)


chr3_-_52719514 1.970 NM_018313
PBRM1
polybromo 1
chr1_+_178694273 1.960 NM_152663
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr16_+_69220940 1.933 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr2_-_218808705 1.862 NM_022648
TNS1
tensin 1
chr12_+_65563339 1.793 NM_001167614
NM_014319
LEMD3

LEM domain containing 3

chr5_-_32313069 1.777 NM_001040446
MTMR12
myotubularin related protein 12
chr17_+_21191347 1.774 NM_002756
MAP2K3
mitogen-activated protein kinase kinase 3
chr8_-_82024277 1.761 NM_018440
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr8_+_87354958 1.747 NM_007013
WWP1
WW domain containing E3 ubiquitin protein ligase 1
chr12_+_122242580 1.731 NM_015048
SETD1B
SET domain containing 1B
chr13_-_41706587 1.714 NM_152903
KBTBD6
kelch repeat and BTB (POZ) domain containing 6
chr15_-_42840992 1.703 NM_153260
LRRC57
leucine rich repeat containing 57
chr7_+_138916230 1.699 NM_173569
UBN2
ubinuclein 2
chrX_-_131573638 1.692 NM_018388
NM_133486
MBNL3

muscleblind-like 3 (Drosophila)

chr13_-_110959441 1.691 NM_001845
COL4A1
collagen, type IV, alpha 1
chr14_-_99737821 1.685 NM_022898
NM_138576
BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein)

chr10_-_75910525 1.656 NM_012095
NM_207012
AP3M1

adaptor-related protein complex 3, mu 1 subunit

chrX_-_100641143 1.612 NM_000061
BTK
Bruton agammaglobulinemia tyrosine kinase
chr3_-_24536176 1.568 NM_000461
NM_001128176
NM_001128177
NM_001252634
THRB



thyroid hormone receptor, beta



chr5_+_56110899 1.547 NM_005921
MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr11_-_64646053 1.541 NM_006795
EHD1
EH-domain containing 1
chr13_+_28712379 1.531 NM_175854
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr20_-_52199635 1.530 NM_006526
ZNF217
zinc finger protein 217
chr9_-_95244750 1.459 NM_001193335
NM_017680
ASPN

asporin

chr2_+_166428845 1.437 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr12_-_23737507 1.400 NM_178010
SOX5
SRY (sex determining region Y)-box 5
chr18_-_60986508 1.378 NM_000633
NM_000657
BCL2

B-cell CLL/lymphoma 2

chr3_+_43328001 1.311 NM_001100594
NM_017719
SNRK

SNF related kinase

chr1_-_115053758 1.301 NM_015906
NM_033020
TRIM33

tripartite motif containing 33

chr21_-_39870303 1.291 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr20_-_10654429 1.263 NM_000214
JAG1
jagged 1
chr3_-_52713728 1.259 NM_018165
NM_181042
PBRM1

polybromo 1

chr14_+_57046490 1.252 NM_017799
C14orf101
chromosome 14 open reading frame 101
chr5_-_38556682 1.248 NM_001127671
LIFR
leukemia inhibitory factor receptor alpha
chr16_+_68298326 1.169 NM_001076785
NM_003983
SLC7A6

solute carrier family 7 (amino acid transporter light chain, y+L system), member 6

chrX_-_131547536 1.159 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr1_+_118148506 1.156 NM_017709
FAM46C
family with sequence similarity 46, member C
chr5_-_88199868 1.147 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr11_-_63536112 1.106 NM_001144936
C11orf95
chromosome 11 open reading frame 95
chr1_+_15853348 1.106 NM_015291
DNAJC16
DnaJ (Hsp40) homolog, subfamily C, member 16
chr12_+_12764755 1.103 NM_001310
CREBL2
cAMP responsive element binding protein-like 2
chr4_-_103790002 1.102 NM_181893
NM_181890
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chrX_-_18372777 1.086 NM_006089
SCML2
sex comb on midleg-like 2 (Drosophila)
chr16_-_4588379 1.059 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr4_+_86851425 1.027 NM_031305
ARHGAP24
Rho GTPase activating protein 24
chr7_+_20370724 0.995 NM_002214
ITGB8
integrin, beta 8
chr8_+_61591239 0.990 NM_017780
CHD7
chromodomain helicase DNA binding protein 7
chr5_-_160975124 0.985 NM_000813
NM_021911
GABRB2

gamma-aminobutyric acid (GABA) A receptor, beta 2

chr4_-_103748649 0.981 NM_181887
NM_181891
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr12_+_32654976 0.977 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr4_-_111563278 0.963 NM_001204397
NM_001204398
NM_001204399
NM_153426
NM_153427
PITX2




paired-like homeodomain 2




chr2_+_148602569 0.931 NM_001616
ACVR2A
activin A receptor, type IIA
chr1_-_151966713 0.920 NM_002966
S100A10
S100 calcium binding protein A10
chr22_+_39101806 0.916 NM_004286
GTPBP1
GTP binding protein 1
chr17_-_40540491 0.915 NM_003150
NM_139276
STAT3

signal transducer and activator of transcription 3 (acute-phase response factor)

chr5_+_72112417 0.909 NM_002270
TNPO1
transportin 1
chr17_-_40540359 0.897 NM_213662
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr16_-_4588738 0.863 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr5_-_88179278 0.851 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr19_+_14491920 0.831 NM_001025160
NM_001784
NM_078481
CD97


CD97 molecule


chr4_+_113152838 0.830 NM_001128426
NM_018569
AP1AR

adaptor-related protein complex 1 associated regulatory protein

chr9_-_98270830 0.825 NM_000264
PTCH1
patched 1
chr4_+_81952118 0.816 NM_001201
BMP3
bone morphogenetic protein 3
chr17_+_17942584 0.799 NM_024052
C17orf39
chromosome 17 open reading frame 39
chr1_+_53192021 0.782 NM_024646
ZYG11B
zyg-11 homolog B (C. elegans)
chr6_+_4021500 0.778 NM_003913
PRPF4B
PRP4 pre-mRNA processing factor 4 homolog B (yeast)
chr12_+_5019048 0.769 NM_000217
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr4_-_111544206 0.763 NM_000325
PITX2
paired-like homeodomain 2
chr12_+_122459791 0.745 NM_001024808
NM_020993
BCL7A

B-cell CLL/lymphoma 7A

chr1_+_36273786 0.716 NM_017629
EIF2C4
eukaryotic translation initiation factor 2C, 4
chr3_+_88188261 0.714 NM_018293
ZNF654
zinc finger protein 654
chr15_-_50978983 0.704 NM_017672
TRPM7
transient receptor potential cation channel, subfamily M, member 7
chr2_+_45878912 0.703 NM_005400
PRKCE
protein kinase C, epsilon
chr9_-_98270321 0.692 NM_001083604
NM_001083605
PTCH1

patched 1

chr9_-_98279246 0.691 NM_001083602
NM_001083603
PTCH1

patched 1

chr15_+_59063389 0.680 NM_001040450
NM_001040453
FAM63B

family with sequence similarity 63, member B

chr7_-_138665853 0.674 NM_001164665
NM_020910
KIAA1549

KIAA1549

chr5_+_139493689 0.669 NM_005859
PURA
purine-rich element binding protein A
chr15_+_94841429 0.669 NM_001159643
NM_018349
MCTP2

multiple C2 domains, transmembrane 2

chr7_-_92463211 0.669 NM_001259
CDK6
cyclin-dependent kinase 6
chr1_-_40367539 0.668 NM_001033081
NM_001033082
NM_005376
MYCL1


v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)


chr7_+_28452143 0.664 NM_182898
CREB5
cAMP responsive element binding protein 5
chr18_+_67956136 0.663 NM_004232
SOCS6
suppressor of cytokine signaling 6
chr19_+_34745452 0.658 NM_014686
KIAA0355
KIAA0355
chr17_+_61627818 0.652 NM_005828
DCAF7
DDB1 and CUL4 associated factor 7
chr7_-_92465929 0.638 NM_001145306
CDK6
cyclin-dependent kinase 6
chr10_-_7661613 0.615 NM_032817
ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr4_-_103748966 0.605 NM_003340
NM_181886
NM_181888
NM_181889
UBE2D3



ubiquitin-conjugating enzyme E2D 3



chr1_+_154377668 0.601 NM_000565
NM_001206866
NM_181359
IL6R


interleukin 6 receptor


chr7_+_28725597 0.587 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr3_+_182511284 0.570 NM_014616
ATP11B
ATPase, class VI, type 11B
chr4_-_103748254 0.556 NM_181892
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr7_-_91875296 0.554 NM_194455
NM_194456
KRIT1

KRIT1, ankyrin repeat containing

chr2_+_20646831 0.550 NM_004040
RHOB
ras homolog gene family, member B
chr3_-_16646244 0.545 NM_001190811
DAZL
deleted in azoospermia-like
chr2_-_201936389 0.544 NM_173822
FAM126B
family with sequence similarity 126, member B
chr13_+_20532788 0.533 NM_003453
NM_197968
NM_001190964
ZMYM2


zinc finger, MYM-type 2


chr21_-_40033617 0.518 NM_001243432
NM_001136154
NM_004449
ERG


v-ets erythroblastosis virus E26 oncogene homolog (avian)


chr17_+_30264039 0.495 NM_015355
SUZ12
suppressor of zeste 12 homolog (Drosophila)
chr4_+_144257982 0.490 NM_002039
NM_207123
GAB1

GRB2-associated binding protein 1

chr13_+_20532906 0.483 NM_001190965
ZMYM2
zinc finger, MYM-type 2
chr12_-_121342050 0.478 NM_139015
SPPL3
signal peptide peptidase-like 3
chr18_-_46477080 0.465 NM_001190821
NM_005904
SMAD7

SMAD family member 7

chr10_+_30722856 0.449 NM_001244134
NM_005204
MAP3K8

mitogen-activated protein kinase kinase kinase 8

chr14_+_33408458 0.446 NM_001164749
NM_001165893
NM_022123
NM_173159
NPAS3



neuronal PAS domain protein 3



chr1_-_220101925 0.438 NM_018713
SLC30A10
solute carrier family 30, member 10
chr3_+_49507470 0.435 NM_001165928
NM_001177634
NM_001177635
NM_001177636
NM_001177637
NM_001177638
NM_001177639
NM_001177640
NM_001177641
NM_001177642
NM_001177644
NM_004393
DAG1











dystroglycan 1 (dystrophin-associated glycoprotein 1)











chr6_-_46922533 0.435 NM_015234
GPR116
G protein-coupled receptor 116
chr16_-_4897265 0.430 NM_032569
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr9_-_16870719 0.424 NM_017637
BNC2
basonuclin 2
chr5_-_150080597 0.407 NM_018047
RBM22
RNA binding motif protein 22
chr16_+_57392694 0.387 NM_002990
CCL22
chemokine (C-C motif) ligand 22
chr7_-_91875108 0.384 NM_004912
NM_001013406
NM_194454
KRIT1


KRIT1, ankyrin repeat containing


chr11_-_44331612 0.380 NM_021926
ALX4
ALX homeobox 4
chr3_+_153839136 0.371 NM_001251963
NM_015595
ARHGEF26

Rho guanine nucleotide exchange factor (GEF) 26

chr6_-_46889620 0.370 NM_001098518
GPR116
G protein-coupled receptor 116
chr7_+_101459092 0.368 NM_001202543
NM_001202544
NM_001202545
NM_001913
NM_181500
NM_001202546
CUX1





cut-like homeobox 1





chr3_-_16646927 0.367 NM_001351
DAZL
deleted in azoospermia-like
chrX_-_19140581 0.342 NM_001079858
NM_001079859
NM_001079860
NM_001184833
NM_001184834
NM_001184835
NM_001184836
NM_001184837
NM_005756
GPR64








G protein-coupled receptor 64








chr11_+_32851469 0.342 NM_024081
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr22_+_46546498 0.302 NM_001001928
NM_005036
PPARA

peroxisome proliferator-activated receptor alpha

chr1_+_33004771 0.301 NM_001040441
ZBTB8A
zinc finger and BTB domain containing 8A
chr12_+_5541273 0.295 NM_001102654
NTF3
neurotrophin 3
chr10_-_94050799 0.288 NM_014912
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr2_+_65283485 0.285 NM_015147
CEP68
centrosomal protein 68kDa
chr9_-_123476578 0.276 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr12_+_85673884 0.256 NM_006982
ALX1
ALX homeobox 1
chr7_+_28338939 0.254 NM_182899
CREB5
cAMP responsive element binding protein 5
chr2_+_7017795 0.246 NM_080657
RSAD2
radical S-adenosyl methionine domain containing 2
chr14_-_92506284 0.242 NM_004239
TRIP11
thyroid hormone receptor interactor 11
chr8_-_119964059 0.232 NM_002546
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr12_-_40013842 0.226 NM_005164
ABCD2
ATP-binding cassette, sub-family D (ALD), member 2
chr1_+_222791151 0.208 NM_198551
MIA3
melanoma inhibitory activity family, member 3
chr14_-_61447711 0.206 NM_020810
TRMT5
TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
chr3_+_10183318 0.205 NM_000551
NM_198156
VHL

von Hippel-Lindau tumor suppressor


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.63 1.21e-08 GO:0050789 regulation of biological process
1.66 2.95e-08 GO:0050794 regulation of cellular process
2.43 2.46e-07 GO:0048519 negative regulation of biological process
1.55 5.54e-07 GO:0065007 biological regulation
2.41 2.71e-06 GO:0048523 negative regulation of cellular process
1.99 1.51e-05 GO:0060255 regulation of macromolecule metabolic process
2.12 3.38e-05 GO:0048518 positive regulation of biological process
3.24 3.73e-05 GO:0050793 regulation of developmental process
2.80 4.11e-05 GO:0051239 regulation of multicellular organismal process
1.85 1.16e-04 GO:0032502 developmental process
1.95 1.68e-04 GO:0048856 anatomical structure development
3.36 1.99e-04 GO:2000026 regulation of multicellular organismal development
2.07 2.56e-04 GO:0010468 regulation of gene expression
1.87 2.72e-04 GO:0007275 multicellular organismal development
1.86 2.74e-04 GO:0080090 regulation of primary metabolic process
2.30 2.84e-04 GO:0048513 organ development
2.96 4.05e-04 GO:0042127 regulation of cell proliferation
1.98 4.27e-04 GO:0048731 system development
1.83 4.52e-04 GO:0031323 regulation of cellular metabolic process
3.41 5.33e-04 GO:0045595 regulation of cell differentiation
14.14 5.66e-04 GO:0030510 regulation of BMP signaling pathway
3.06 6.45e-04 GO:0009888 tissue development
2.04 1.02e-03 GO:0048522 positive regulation of cellular process
3.40 1.04e-03 GO:0007167 enzyme linked receptor protein signaling pathway
2.65 1.41e-03 GO:0010604 positive regulation of macromolecule metabolic process
15.82 1.89e-03 GO:0045768 positive regulation of anti-apoptosis
2.58 2.49e-03 GO:0031325 positive regulation of cellular metabolic process
1.72 2.82e-03 GO:0019222 regulation of metabolic process
2.89 3.00e-03 GO:0006351 transcription, DNA-dependent
2.35 3.57e-03 GO:0009653 anatomical structure morphogenesis
3.22 4.31e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
3.33 4.71e-03 GO:0009887 organ morphogenesis
2.01 4.99e-03 GO:0051252 regulation of RNA metabolic process
3.31 5.10e-03 GO:0010629 negative regulation of gene expression
2.78 5.79e-03 GO:0010605 negative regulation of macromolecule metabolic process
12.94 6.38e-03 GO:0045767 regulation of anti-apoptosis
12.94 6.38e-03 GO:0060021 palate development
4.91 6.64e-03 GO:0051241 negative regulation of multicellular organismal process
8.08 6.70e-03 GO:0030278 regulation of ossification
3.72 7.12e-03 GO:0051094 positive regulation of developmental process
2.43 7.59e-03 GO:0009893 positive regulation of metabolic process
1.63 7.70e-03 GO:0044260 cellular macromolecule metabolic process
29.20 7.90e-03 GO:0032925 regulation of activin receptor signaling pathway
3.20 8.31e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.92 9.60e-03 GO:0010556 regulation of macromolecule biosynthetic process
4.71 1.02e-02 GO:0030334 regulation of cell migration
3.03 1.08e-02 GO:0009890 negative regulation of biosynthetic process
1.93 1.13e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
4.65 1.15e-02 GO:2000145 regulation of cell motility
2.15 1.22e-02 GO:0016070 RNA metabolic process
4.58 1.35e-02 GO:0001568 blood vessel development
3.53 1.37e-02 GO:0072358 cardiovascular system development
3.53 1.37e-02 GO:0072359 circulatory system development
2.60 1.70e-02 GO:0032774 RNA biosynthetic process
4.12 1.83e-02 GO:0051093 negative regulation of developmental process
2.07 1.95e-02 GO:0010467 gene expression
2.57 2.08e-02 GO:0009892 negative regulation of metabolic process
2.99 2.11e-02 GO:0051254 positive regulation of RNA metabolic process
2.15 2.21e-02 GO:0023051 regulation of signaling
4.01 2.41e-02 GO:0045597 positive regulation of cell differentiation
2.97 2.42e-02 GO:0010628 positive regulation of gene expression
2.94 2.77e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.83 2.80e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4.25 2.81e-02 GO:0001944 vasculature development
4.25 2.81e-02 GO:0040012 regulation of locomotion
3.04 2.84e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.23 2.91e-02 GO:0009987 cellular process
4.24 2.91e-02 GO:0051270 regulation of cellular component movement
6.61 2.95e-02 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
2.78 3.68e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.22 4.12e-02 GO:0008284 positive regulation of cell proliferation
2.30 4.24e-02 GO:0002376 immune system process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.58 8.03e-05 GO:0005634 nucleus

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.07 7.22e-06 GO:0001071 nucleic acid binding transcription factor activity
3.07 7.22e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.48 3.16e-05 GO:0005515 protein binding
1.81 2.79e-04 GO:0003676 nucleic acid binding
2.01 4.17e-04 GO:0003677 DNA binding
3.10 8.18e-04 GO:0043565 sequence-specific DNA binding
12.66 1.37e-03 GO:0046332 SMAD binding
7.10 3.28e-03 GO:0019838 growth factor binding
1.21 4.59e-03 GO:0005488 binding