Motif ID: AGUGCAA

Z-value: 1.127


Mature miRNA associated with seed AGUGCAA:

NamemiRBase Accession
hsa-miR-130a MIMAT0000425
hsa-miR-130b MIMAT0000691
hsa-miR-301a MIMAT0000688
hsa-miR-301b MIMAT0004958
hsa-miR-3666 MIMAT0018088
hsa-miR-4295 MIMAT0016844
hsa-miR-454 MIMAT0003885



Activity profile for motif AGUGCAA.

activity profile for motif AGUGCAA


Sorted Z-values histogram for motif AGUGCAA

Sorted Z-values for motif AGUGCAA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGUGCAA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_60337350 31.661 NM_021136
RTN1
reticulon 1
chr20_+_10199455 29.206 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr14_-_60097531 29.028 NM_206852
RTN1
reticulon 1
chr8_+_26435339 19.639 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chr20_+_44650260 19.201 NM_001134771
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr8_+_26371461 18.494 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr20_+_44657812 17.898 NM_020708
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr14_-_21493910 17.774 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr3_+_115342150 16.757 NM_001130064
NM_002045
GAP43

growth associated protein 43

chr14_-_21493122 16.254 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr1_-_204380903 15.944 NM_032833
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr2_+_131674223 15.874 NM_015320
NM_032995
ARHGEF4

Rho guanine nucleotide exchange factor (GEF) 4

chr8_-_110657025 14.181 NM_001099753
NM_001099754
NM_001099755
SYBU


syntabulin (syntaxin-interacting)


chr8_-_110704019 14.019 NM_001099743
NM_001099744
SYBU

syntabulin (syntaxin-interacting)

chr17_-_78450247 13.809 NM_002522
NPTX1
neuronal pentraxin I
chr1_+_160085519 13.766 NM_000702
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr15_-_83316621 13.664 NM_030594
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr16_-_57318574 13.644 NM_015993
PLLP
plasmolipin
chr11_-_45687135 13.559 NM_003654
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr8_-_110693233 13.281 NM_001099745
NM_001099746
SYBU

syntabulin (syntaxin-interacting)

chr8_-_110657745 13.107 NM_001099751
NM_001099752
SYBU

syntabulin (syntaxin-interacting)

chr9_-_79520878 13.002 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr22_-_21213099 12.733 NM_058004
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr3_+_50712671 12.643 NM_004947
DOCK3
dedicator of cytokinesis 3
chr1_+_28099682 11.877 NM_177424
STX12
syntaxin 12
chr8_-_110655418 11.819 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr8_-_110661007 11.776 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chr1_-_52831817 11.204 NM_032449
CC2D1B
coiled-coil and C2 domain containing 1B
chr2_-_86565205 11.162 NM_001164730
REEP1
receptor accessory protein 1
chr2_-_2334887 11.075 NM_015025
MYT1L
myelin transcription factor 1-like
chr2_-_86564632 11.069 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr12_-_26277807 10.942 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr9_-_138987096 10.771 NM_144653
NACC2
NACC family member 2, BEN and BTB (POZ) domain containing
chr5_-_138211054 10.644 NM_015564
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr17_+_18218569 10.626 NM_144775
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr1_+_11866206 10.073 NM_001286
NM_021735
NM_021736
NM_021737
CLCN6



chloride channel 6



chr4_-_36245893 10.005 NM_015230
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr20_+_34742656 9.973 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr8_+_11141983 9.850 NM_015458
MTMR9
myotubularin related protein 9
chr7_+_45614081 9.719 NM_021116
ADCY1
adenylate cyclase 1 (brain)
chr11_-_46939908 9.541 NM_002334
LRP4
low density lipoprotein receptor-related protein 4
chrX_+_53111482 9.497 NM_022117
TSPYL2
TSPY-like 2
chr6_-_91006460 9.393 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr6_-_88875766 8.986 NM_001160226
NM_001160258
NM_001160259
NM_016083
CNR1



cannabinoid receptor 1 (brain)



chr22_-_21088954 8.916 NM_002650
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr7_+_94138991 8.906 NM_022900
CASD1
CAS1 domain containing 1
chr19_-_17799005 8.851 NM_001080421
UNC13A
unc-13 homolog A (C. elegans)
chr5_-_136834887 8.801 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr1_-_51984994 8.725 NM_001981
EPS15
epidermal growth factor receptor pathway substrate 15
chr6_-_108145507 8.658 NM_198081
SCML4
sex comb on midleg-like 4 (Drosophila)
chr1_-_226926875 8.558 NM_002221
ITPKB
inositol-trisphosphate 3-kinase B
chr8_-_91094924 8.399 NM_004929
CALB1
calbindin 1, 28kDa
chr11_-_113746205 8.356 NM_020886
USP28
ubiquitin specific peptidase 28
chr6_-_91006580 8.343 NM_001170794
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr19_+_49122789 8.334 NM_001204159
SPHK2
sphingosine kinase 2
chr19_+_49122547 8.270 NM_001204158
NM_001243876
NM_020126
SPHK2


sphingosine kinase 2


chr5_+_71403040 8.254 NM_005909
MAP1B
microtubule-associated protein 1B
chr10_-_126432893 8.163 NM_014661
FAM53B
family with sequence similarity 53, member B
chr20_+_1246959 8.077 NM_014723
SNPH
syntaphilin
chr20_+_34700257 8.046 NM_177996
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr19_-_10341947 7.921 NM_004230
S1PR2
sphingosine-1-phosphate receptor 2
chr4_+_55523906 7.780 NM_000222
NM_001093772
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr17_-_56406120 7.615 NM_004758
NM_024418
BZRAP1

benzodiazapine receptor (peripheral) associated protein 1

chr17_+_8339135 7.603 NM_001025579
NM_030808
NDEL1

nudE nuclear distribution gene E homolog (A. nidulans)-like 1

chr11_-_70507911 7.568 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr20_-_48532067 7.512 NM_006038
SPATA2
spermatogenesis associated 2
chr10_-_104178900 7.455 NM_002779
PSD
pleckstrin and Sec7 domain containing
chr9_-_135819995 7.399 NM_000368
NM_001162426
NM_001162427
TSC1


tuberous sclerosis 1


chr8_-_53322200 7.042 NM_014682
ST18
suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)
chr1_+_244214552 6.948 NM_205768
ZNF238
zinc finger protein 238
chr1_+_101702304 6.828 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chr6_+_44238479 6.799 NM_001137560
TMEM151B
transmembrane protein 151B
chr1_+_84609941 6.752 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr20_+_11871364 6.715 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr9_-_10612722 6.623 NM_002839
PTPRD
protein tyrosine phosphatase, receptor type, D
chr9_+_99212379 6.599 NM_014282
HABP4
hyaluronan binding protein 4
chr6_+_101846860 6.546 NM_001166247
NM_021956
NM_175768
GRIK2


glutamate receptor, ionotropic, kainate 2


chr18_-_65183922 6.531 NM_032160
DSEL
dermatan sulfate epimerase-like
chr10_-_73611050 6.527 NM_001042465
NM_001042466
NM_002778
PSAP


prosaposin


chrX_-_54384436 6.508 NM_001002838
NM_020922
WNK3

WNK lysine deficient protein kinase 3

chr18_+_23806385 6.481 NM_005640
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr1_-_202612580 6.340 NM_001136504
SYT2
synaptotagmin II
chr10_-_81205091 6.301 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr3_+_4535030 6.279 NM_001099952
NM_001168272
NM_002222
ITPR1


inositol 1,4,5-trisphosphate receptor, type 1


chr3_-_10547267 6.277 NM_001001331
NM_001683
ATP2B2

ATPase, Ca++ transporting, plasma membrane 2

chr2_-_27718098 6.239 NM_022823
FNDC4
fibronectin type III domain containing 4
chr9_-_36400817 6.125 NM_194328
NM_194332
RNF38

ring finger protein 38

chr5_+_7396030 6.122 NM_020546
ADCY2
adenylate cyclase 2 (brain)
chr1_-_109584589 6.103 NM_001142550
NM_001142551
NM_014969
WDR47


WD repeat domain 47


chr15_+_99645152 6.068 NM_015286
NM_145728
SYNM

synemin, intermediate filament protein

chr1_+_84630014 5.954 NM_001242857
NM_001242858
NM_001242859
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr6_+_46097700 5.925 NM_014936
ENPP4
ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
chr9_+_100263818 5.890 NM_003275
TMOD1
tropomodulin 1
chr1_-_202679415 5.883 NM_177402
SYT2
synaptotagmin II
chr2_+_173600519 5.865 NM_007023
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr16_+_50776012 5.837 NM_001042412
CYLD
cylindromatosis (turban tumor syndrome)
chr9_+_100263461 5.813 NM_001166116
TMOD1
tropomodulin 1
chr13_-_36920777 5.791 NM_001142295
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr16_+_50775960 5.778 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr5_-_58334936 5.776 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr1_+_6845381 5.774 NM_001195563
NM_001242701
NM_015215
CAMTA1


calmodulin binding transcription activator 1


chr8_-_22550708 5.766 NM_004430
EGR3
early growth response 3
chr17_+_53342320 5.721 NM_002126
HLF
hepatic leukemia factor
chr20_-_36156082 5.697 NM_001167822
NM_001167821
BLCAP

bladder cancer associated protein

chr11_-_70935807 5.694 NM_012309
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr15_-_49338496 5.666 NM_001193489
NM_014701
SECISBP2L

SECIS binding protein 2-like

chr6_-_136871956 5.660 NM_001198616
NM_001198617
NM_003980
MAP7


microtubule-associated protein 7


chr1_-_23857711 5.619 NM_004091
E2F2
E2F transcription factor 2
chr1_-_45956795 5.587 NM_007170
TESK2
testis-specific kinase 2
chr1_+_78245306 5.570 NM_198549
FAM73A
family with sequence similarity 73, member A
chr1_-_6240082 5.565 NM_015557
CHD5
chromodomain helicase DNA binding protein 5
chr2_+_173686314 5.462 NM_001100397
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr20_-_36156282 5.455 NM_001167820
NM_006698
BLCAP

bladder cancer associated protein

chr4_-_87028805 5.441 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr11_-_18655962 5.381 NM_194285
SPTY2D1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr16_+_85061303 5.378 NM_014732
KIAA0513
KIAA0513
chr3_-_15900928 5.312 NM_015199
ANKRD28
ankyrin repeat domain 28
chr13_+_42846255 5.305 NM_016248
AKAP11
A kinase (PRKA) anchor protein 11
chr20_+_19193282 5.249 NM_020689
SLC24A3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr10_-_30348433 5.238 NM_020848
KIAA1462
KIAA1462
chr9_-_36401149 5.225 NM_194330
RNF38
ring finger protein 38
chr6_-_167040700 5.154 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr3_-_66550844 5.130 NM_015541
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr8_-_22549901 5.121 NM_001199880
EGR3
early growth response 3
chr18_+_54318561 5.026 NM_015285
NM_052834
WDR7

WD repeat domain 7

chr11_-_31839447 4.994 NM_001127612
PAX6
paired box 6
chr2_-_182545212 4.972 NM_002500
CERKL
NEUROD1
ceramide kinase-like
neurogenic differentiation 1
chr13_-_36920603 4.968 NM_001142296
NM_015087
SPG20

spastic paraplegia 20 (Troyer syndrome)

chr15_+_31619043 4.964 NM_015995
KLF13
Kruppel-like factor 13
chr1_-_243418675 4.938 NM_001042404
NM_001042405
NM_014812
CEP170


centrosomal protein 170kDa


chr2_+_74273449 4.877 NM_144993
TET3
tet methylcytosine dioxygenase 3
chr18_+_48556483 4.867 NM_005359
SMAD4
SMAD family member 4
chr14_-_50698090 4.835 NM_006939
SOS2
son of sevenless homolog 2 (Drosophila)
chr9_-_26947435 4.826 NM_001031689
PLAA
phospholipase A2-activating protein
chr13_-_95364248 4.774 NM_007084
SOX21
SRY (sex determining region Y)-box 21
chr14_-_45431121 4.768 NM_017658
KLHL28
kelch-like 28 (Drosophila)
chr1_+_84647342 4.753 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr2_-_213403280 4.742 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr7_-_50861114 4.729 NM_001001555
GRB10
growth factor receptor-bound protein 10
chr3_-_15140652 4.716 NM_022340
ZFYVE20
zinc finger, FYVE domain containing 20
chr1_+_244216506 4.697 NM_006352
ZNF238
zinc finger protein 238
chr11_-_118661898 4.695 NM_004397
DDX6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
chr2_+_25016174 4.685 NM_001199803
NM_024322
CENPO

centromere protein O

chr1_+_151584514 4.645 NM_030918
SNX27
sorting nexin family member 27
chr15_-_83240499 4.535 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr20_+_4666796 4.514 NM_000311
NM_001080121
NM_001080122
NM_183079
NM_001080123
PRNP




prion protein




chr4_-_87374282 4.483 NM_002753
MAPK10
mitogen-activated protein kinase 10
chr10_+_86088156 4.470 NM_018999
FAM190B
family with sequence similarity 190, member B
chr2_+_70142152 4.393 NM_001202513
NM_001202514
NM_002357
MXD1


MAX dimerization protein 1


chr12_-_113574020 4.392 NM_001193520
NM_004658
RASAL1

RAS protein activator like 1 (GAP1 like)

chr5_-_171433876 4.323 NM_012300
NM_033644
NM_033645
FBXW11


F-box and WD repeat domain containing 11


chr2_-_70781146 4.279 NM_001099691
NM_003236
TGFA

transforming growth factor, alpha

chr2_-_11484699 4.217 NM_004850
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr9_-_132805456 4.182 NM_015033
FNBP1
formin binding protein 1
chr4_-_87281374 4.093 NM_138980
NM_138982
MAPK10

mitogen-activated protein kinase 10

chr17_-_42580927 4.033 NM_001002909
GPATCH8
G patch domain containing 8
chr22_+_38004454 4.000 NM_001001560
NM_001001561
NM_001172687
NM_013365
GGA1



golgi-associated, gamma adaptin ear containing, ARF binding protein 1



chr13_-_45150601 3.985 NM_001243799
NM_183422
TSC22D1

TSC22 domain family, member 1

chr2_+_149632772 3.980 NM_004522
KIF5C
kinesin family member 5C
chr12_-_53893195 3.965 NM_001193511
NM_006301
MAP3K12

mitogen-activated protein kinase kinase kinase 12

chr6_+_69344939 3.958 NM_001704
BAI3
brain-specific angiogenesis inhibitor 3
chr11_-_46722115 3.952 NM_004308
ARHGAP1
Rho GTPase activating protein 1
chr3_+_16926451 3.907 NM_001144382
PLCL2
phospholipase C-like 2
chr6_-_90121966 3.899 NM_021244
RRAGD
Ras-related GTP binding D
chr8_-_22550057 3.896 NM_001199881
EGR3
early growth response 3
chr18_-_53255734 3.888 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr5_-_58295758 3.855 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_-_183731279 3.841 NM_001463
FRZB
frizzled-related protein
chr12_-_113573267 3.818 NM_001193521
RASAL1
RAS protein activator like 1 (GAP1 like)
chr15_-_64648359 3.773 NM_022048
CSNK1G1
casein kinase 1, gamma 1
chr12_-_56615679 3.772 NM_005785
NM_194358
NM_194359
RNF41


ring finger protein 41


chr7_+_138916230 3.760 NM_173569
UBN2
ubinuclein 2
chrX_+_38660653 3.746 NM_001098790
NM_001098791
MID1IP1

MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))

chr18_+_9136742 3.742 NM_001083625
NM_015208
ANKRD12

ankyrin repeat domain 12

chr4_+_139936938 3.734 NM_012118
CCRN4L
CCR4 carbon catabolite repression 4-like (S. cerevisiae)
chr1_-_36023005 3.721 NM_024874
KIAA0319L
KIAA0319-like
chr4_+_95679075 3.717 NM_001203
BMPR1B
bone morphogenetic protein receptor, type IB
chr15_+_40509628 3.711 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr7_-_27159213 3.687 NM_030661
HOXA3
homeobox A3
chr5_-_133512641 3.668 NM_006930
NM_170679
SKP1

S-phase kinase-associated protein 1

chr5_-_58652671 3.663 NM_001197219
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_-_18480203 3.610 NM_001131010
SATB1
SATB homeobox 1
chr6_-_167275657 3.600 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr8_+_59323822 3.588 NM_001077619
UBXN2B
UBX domain protein 2B
chr6_+_121756744 3.582 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr4_+_86396251 3.567 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr10_+_31610063 3.559 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr2_+_177053306 3.555 NM_024501
HOXD1
homeobox D1
chr6_-_143266283 3.531 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr15_-_34502269 3.526 NM_024713
C15orf29
chromosome 15 open reading frame 29
chr6_-_136847743 3.513 NM_001198614
NM_001198618
NM_001198619
MAP7


microtubule-associated protein 7


chr6_-_136788012 3.494 NM_001198615
MAP7
microtubule-associated protein 7
chr1_+_84630575 3.488 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr5_-_65017874 3.483 NM_019072
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr3_-_48130633 3.465 NM_001134364
NM_002375
NM_030885
MAP4


microtubule-associated protein 4


chr13_-_45011059 3.461 NM_006022
TSC22D1
TSC22 domain family, member 1
chr16_+_19125243 3.444 NM_001034841
ITPRIPL2
inositol 1,4,5-trisphosphate receptor interacting protein-like 2
chr1_-_51887740 3.437 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr13_+_35516390 3.420 NM_015678
NBEA
neurobeachin
chr22_-_50523780 3.413 NM_139202
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.89 3.35e-13 GO:0023052 signaling
2.59 3.07e-12 GO:0007399 nervous system development
1.52 4.76e-12 GO:0050794 regulation of cellular process
1.47 4.86e-12 GO:0065007 biological regulation
1.49 5.80e-12 GO:0050789 regulation of biological process
1.85 3.14e-10 GO:0007165 signal transduction
2.10 5.08e-09 GO:0048869 cellular developmental process
2.11 6.95e-09 GO:0030154 cell differentiation
1.70 5.15e-08 GO:0032502 developmental process
1.85 5.36e-08 GO:0048731 system development
1.79 8.36e-08 GO:0048856 anatomical structure development
1.65 1.07e-07 GO:0051716 cellular response to stimulus
1.70 6.07e-07 GO:0007275 multicellular organismal development
2.12 1.39e-06 GO:0023051 regulation of signaling
2.92 2.23e-06 GO:0007167 enzyme linked receptor protein signaling pathway
1.60 7.39e-06 GO:0019222 regulation of metabolic process
2.55 9.61e-06 GO:0048699 generation of neurons
2.34 1.76e-05 GO:0010646 regulation of cell communication
2.08 1.92e-05 GO:0009653 anatomical structure morphogenesis
2.46 2.09e-05 GO:0022008 neurogenesis
3.03 2.76e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.61 4.31e-05 GO:0080090 regulation of primary metabolic process
1.46 4.52e-05 GO:0032501 multicellular organismal process
1.60 5.00e-05 GO:0031323 regulation of cellular metabolic process
1.20 1.79e-04 GO:0009987 cellular process
1.37 3.94e-04 GO:0050896 response to stimulus
2.53 4.03e-04 GO:0030182 neuron differentiation
3.21 5.34e-04 GO:0007420 brain development
2.79 7.41e-04 GO:0007417 central nervous system development
2.17 1.12e-03 GO:0007154 cell communication
2.78 1.29e-03 GO:0019226 transmission of nerve impulse
2.78 1.29e-03 GO:0035637 multicellular organismal signaling
1.97 1.35e-03 GO:0035556 intracellular signal transduction
16.08 1.60e-03 GO:0021846 cell proliferation in forebrain
2.38 1.73e-03 GO:0006468 protein phosphorylation
1.80 1.93e-03 GO:0006464 protein modification process
1.93 2.29e-03 GO:0009966 regulation of signal transduction
1.54 2.41e-03 GO:0060255 regulation of macromolecule metabolic process
1.97 3.00e-03 GO:0051239 regulation of multicellular organismal process
2.31 3.36e-03 GO:0007267 cell-cell signaling
1.61 3.77e-03 GO:0031326 regulation of cellular biosynthetic process
1.59 6.02e-03 GO:0009889 regulation of biosynthetic process
1.73 6.21e-03 GO:0043412 macromolecule modification
2.07 6.38e-03 GO:0006793 phosphorus metabolic process
2.07 6.38e-03 GO:0006796 phosphate metabolic process
2.28 6.60e-03 GO:2000026 regulation of multicellular organismal development
1.61 7.33e-03 GO:0010468 regulation of gene expression
2.71 7.63e-03 GO:0008283 cell proliferation
1.75 8.12e-03 GO:0007166 cell surface receptor linked signaling pathway
1.62 9.45e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.16 1.26e-02 GO:0016310 phosphorylation
1.60 1.41e-02 GO:0010556 regulation of macromolecule biosynthetic process
2.07 1.83e-02 GO:0048468 cell development
1.70 1.89e-02 GO:0048513 organ development
2.26 2.01e-02 GO:0019220 regulation of phosphate metabolic process
2.26 2.01e-02 GO:0051174 regulation of phosphorus metabolic process
2.90 2.29e-02 GO:0070647 protein modification by small protein conjugation or removal
2.23 2.52e-02 GO:0043085 positive regulation of catalytic activity
2.25 2.82e-02 GO:0010628 positive regulation of gene expression
2.25 2.82e-02 GO:0042325 regulation of phosphorylation
1.62 2.88e-02 GO:0006355 regulation of transcription, DNA-dependent
2.94 2.97e-02 GO:0033674 positive regulation of kinase activity
2.04 3.46e-02 GO:0050793 regulation of developmental process
1.54 3.65e-02 GO:0048518 positive regulation of biological process
2.42 3.86e-02 GO:0010647 positive regulation of cell communication
1.54 3.93e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.58 4.15e-02 GO:0048519 negative regulation of biological process
1.57 4.26e-02 GO:0048522 positive regulation of cellular process
2.40 4.30e-02 GO:0023056 positive regulation of signaling
2.09 4.41e-02 GO:0044093 positive regulation of molecular function
2.85 4.59e-02 GO:0051347 positive regulation of transferase activity

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
4.50 3.08e-04 GO:0005769 early endosome
6.35 7.83e-03 GO:0031901 early endosome membrane
1.14 1.39e-02 GO:0005622 intracellular
2.39 1.89e-02 GO:0005768 endosome
1.14 3.36e-02 GO:0044424 intracellular part
3.48 4.40e-02 GO:0045121 membrane raft

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.36 1.54e-06 GO:0005515 protein binding
1.19 3.93e-06 GO:0005488 binding
2.61 4.85e-06 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.43 3.56e-05 GO:0016301 kinase activity
2.22 6.58e-05 GO:0001071 nucleic acid binding transcription factor activity
2.22 6.58e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
2.15 6.79e-04 GO:0016772 transferase activity, transferring phosphorus-containing groups
2.03 1.75e-03 GO:0030528 transcription regulator activity
2.66 2.04e-03 GO:0004674 protein serine/threonine kinase activity
2.36 2.17e-03 GO:0004672 protein kinase activity
1.77 3.61e-03 GO:0030554 adenyl nucleotide binding
1.75 6.03e-03 GO:0032559 adenyl ribonucleotide binding
1.66 6.34e-03 GO:0017076 purine nucleotide binding
2.20 6.64e-03 GO:0043565 sequence-specific DNA binding
1.74 7.54e-03 GO:0005524 ATP binding
1.64 9.80e-03 GO:0032553 ribonucleotide binding
1.64 9.80e-03 GO:0032555 purine ribonucleotide binding
1.62 1.97e-02 GO:0035639 purine ribonucleoside triphosphate binding
7.35 4.39e-02 GO:0004843 ubiquitin-specific protease activity