Motif ID: ARID5B.p2

Z-value: 0.654


Transcription factors associated with ARID5B.p2:

Gene SymbolEntrez IDGene Name
ARID5B 84159 AT rich interactive domain 5B (MRF1-like)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ARID5Bchr10_+_63808968,
chr10_+_63661012
-0.036.6e-01Click!


Activity profile for motif ARID5B.p2.

activity profile for motif ARID5B.p2


Sorted Z-values histogram for motif ARID5B.p2

Sorted Z-values for motif ARID5B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ARID5B.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_102123420 18.161


chrX_+_119738542 11.996 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chr7_+_116660291 11.304 ST7
suppression of tumorigenicity 7
chr1_-_8931634 9.444 NM_001201483
ENO1
enolase 1, (alpha)
chr3_-_79817058 9.321 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr4_+_1902352 9.200 NM_133334
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr5_+_52856460 9.124 NM_002495
NDUFS4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr5_+_52856472 8.662 NDUFS4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr7_-_104909442 7.993 NM_182691
SRPK2
SRSF protein kinase 2
chr2_+_172821874 7.761 HAT1
histone acetyltransferase 1
chr10_+_71029755 7.725 NM_033497
NM_033498
NM_033500
HK1


hexokinase 1


chrX_+_119737743 7.561 NM_014060
MCTS1
malignant T cell amplified sequence 1
chr7_+_77469446 7.446 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr5_+_137673223 7.382 NM_001135647
FAM53C
family with sequence similarity 53, member C
chr13_+_53216564 7.300 HNRNPA1L2
heterogeneous nuclear ribonucleoprotein A1-like 2
chr2_-_55199894 7.126


chr7_-_24797557 7.044 NM_001127454
NM_004403
DFNA5

deafness, autosomal dominant 5

chr2_-_170430312 6.718 NM_024622
FASTKD1
FAST kinase domains 1
chr1_-_85742586 6.112 NM_003921
BCL10
B-cell CLL/lymphoma 10
chr14_+_67831484 6.093 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr12_-_102512277 6.082 NM_024057
NUP37
nucleoporin 37kDa
chr17_-_1248346 6.058 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr15_+_80364902 5.935 NM_001242915
NM_001242916
ZFAND6

zinc finger, AN1-type domain 6

chr5_+_65372744 5.825 ERBB2IP
erbb2 interacting protein
chr4_+_41700736 5.723 LIMCH1
LIM and calponin homology domains 1
chr6_-_86351156 5.651 NM_001159675
NM_001159676
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr12_-_50616425 5.636 NM_001113547
LIMA1
LIM domain and actin binding 1
chr7_+_143079925 5.600 ZYX
zyxin
chr6_-_79675672 5.566 PHIP
pleckstrin homology domain interacting protein
chr10_-_75193297 5.552 NM_001024593
ZMYND17
zinc finger, MYND-type containing 17
chr4_+_54292035 5.501 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr10_-_98290309 5.493 TM9SF3
transmembrane 9 superfamily member 3
chr14_+_62164339 5.410 NM_001243084
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr1_+_116925991 5.393 NM_001160234
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr11_+_101983170 5.376 NM_001195045
YAP1
Yes-associated protein 1
chr15_-_55562483 5.336 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr2_+_27851514 5.270 NM_001145047
NM_001145048
NM_001145049
GPN1


GPN-loop GTPase 1


chr15_+_52201590 5.167 TMOD3
tropomodulin 3 (ubiquitous)
chr2_+_170662044 5.068 SSB
Sjogren syndrome antigen B (autoantigen La)
chr6_+_24775154 4.898 NM_001251989
NM_001251990
NM_015895
GMNN


geminin, DNA replication inhibitor


chr6_-_32139156 4.876 AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr9_+_706744 4.863 NM_153186
KANK1
KN motif and ankyrin repeat domains 1
chr6_+_64286348 4.774 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr6_-_32812711 4.703 NM_004159
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr2_-_37544165 4.563 NM_005813
PRKD3
protein kinase D3
chr14_+_64680858 4.520 NM_182913
SYNE2
spectrin repeat containing, nuclear envelope 2
chr2_+_183608329 4.411 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr2_-_74382352 4.284


chr2_+_102508333 4.276 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_-_200329810 4.066 NM_001172517
SATB2
SATB homeobox 2
chr20_+_19915716 4.004 RIN2
Ras and Rab interactor 2
chr5_-_98262217 3.782 NM_001270
CHD1
chromodomain helicase DNA binding protein 1
chr2_+_102508377 3.742 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_+_201756639 3.621 NM_001142356
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr1_-_247054277 3.588 AHCTF1
AT hook containing transcription factor 1
chr2_+_183582667 3.565 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr14_+_102276279 3.545 PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr1_+_171481164 3.477 PRRC2C
proline-rich coiled-coil 2C
chrX_-_10535476 3.429 NM_001193278
NM_001193279
NM_001193280
NM_001193281
MID1



midline 1 (Opitz/BBB syndrome)



chr3_-_49399969 3.413 RHOA
ras homolog gene family, member A
chr2_+_223725675 3.320 NM_004457
NM_203372
ACSL3

acyl-CoA synthetase long-chain family member 3

chr15_+_66694216 3.277 MAP2K1
mitogen-activated protein kinase kinase 1
chr14_+_102276125 3.140 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr9_+_12693385 3.047 NM_000550
TYRP1
tyrosinase-related protein 1
chr5_+_132432880 3.031 HSPA4
heat shock 70kDa protein 4
chr2_+_198380294 2.834 NM_199482
MOB4
MOB family member 4, phocein
chr4_+_76995862 2.814 NM_001130016
NM_001179
ART3

ADP-ribosyltransferase 3

chr5_+_154393259 2.793 NM_001099293
KIF4B
kinesin family member 4B
chr10_+_124913759 2.792 NM_001007793
NM_004725
BUB3

budding uninhibited by benzimidazoles 3 homolog (yeast)

chr3_+_159557649 2.777 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr5_+_68462836 2.728 NM_031966
CCNB1
cyclin B1
chr3_+_23851933 2.728 NM_001202476
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr1_+_84647342 2.723 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr5_-_94224601 2.722 MCTP1
multiple C2 domains, transmembrane 1
chr4_+_88896838 2.703 SPP1
secreted phosphoprotein 1
chr1_-_51425918 2.701 NM_007051
FAF1
Fas (TNFRSF6) associated factor 1
chr3_+_172472246 2.661 NM_018098
ECT2
epithelial cell transforming sequence 2 oncogene
chr8_+_17822093 2.602 PCM1
pericentriolar material 1
chr3_-_185641596 2.561 TRA2B
transformer 2 beta homolog (Drosophila)
chr12_+_48516428 2.483 NM_001166687
NM_001166688
PFKM

phosphofructokinase, muscle

chr17_-_41276112 2.466 NM_007298
BRCA1
breast cancer 1, early onset
chr1_-_51887740 2.408 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr1_+_236557643 2.395 NM_145861
EDARADD
EDAR-associated death domain
chr13_-_37679800 2.379 NM_145203
CSNK1A1L
casein kinase 1, alpha 1-like
chrX_-_110654373 2.369 NM_000555
DCX
doublecortin
chr11_-_71746966 2.325


chr10_-_98336445 2.317 TM9SF3
transmembrane 9 superfamily member 3
chr7_+_116660263 2.244 ST7
suppression of tumorigenicity 7
chr14_+_74035762 2.235 NM_006821
ACOT2
acyl-CoA thioesterase 2
chr18_-_46469118 2.164 NM_001190823
SMAD7
SMAD family member 7
chr3_-_141747434 2.142 NM_001178141
NM_001178142
NM_006286
TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chr15_-_25650647 2.116 NM_130838
UBE3A
ubiquitin protein ligase E3A
chr2_-_44586854 2.116 NM_001042385
NM_001042386
PREPL

prolyl endopeptidase-like

chrX_-_33229428 2.096 NM_004006
DMD
dystrophin
chr1_+_210001399 2.091 DIEXF
digestive organ expansion factor homolog (zebrafish)
chr8_+_74903563 2.064 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr12_-_50595303 2.062 NM_001243775
LIMA1
LIM domain and actin binding 1
chr15_-_56209305 2.038 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr4_+_88896801 2.011 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr5_-_142815076 1.970 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr18_+_72166822 1.921 NM_001168499
CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr15_-_42749710 1.858 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr17_-_8424217 1.832 MYH10
myosin, heavy chain 10, non-muscle
chr6_+_97010423 1.763 NM_001170807
NM_020482
FHL5

four and a half LIM domains 5

chrX_-_131547536 1.748 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr1_+_52082545 1.740 NM_024586
NM_148906
NM_148908
NM_148909
OSBPL9



oxysterol binding protein-like 9



chr3_-_98241748 1.732 CLDND1
claudin domain containing 1
chr15_-_80263460 1.714 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr22_-_43042976 1.711 NM_001129819
NM_001171661
NM_007326
CYB5R3


cytochrome b5 reductase 3


chr1_+_210001267 1.703 NM_014388
DIEXF
digestive organ expansion factor homolog (zebrafish)
chr18_+_9102618 1.701 NM_021074
NDUFV2
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr20_+_11898536 1.697 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr9_-_88715024 1.692 NM_177937
GOLM1
golgi membrane protein 1
chr15_+_42696957 1.676 NM_173089
NM_173090
CAPN3

calpain 3, (p94)

chr20_+_1093905 1.667 NM_178578
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr4_+_88896868 1.647 SPP1
secreted phosphoprotein 1
chr12_+_64803741 1.633 XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr3_+_159557745 1.603 SCHIP1
schwannomin interacting protein 1
chr1_+_36636690 1.599 MAP7D1
MAP7 domain containing 1
chr7_-_41742666 1.590 NM_002192
INHBA
inhibin, beta A
chr6_+_64231626 1.587 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr4_+_169013687 1.574 NM_007193
ANXA10
annexin A10
chr18_+_20513277 1.563 NM_002894
RBBP8
retinoblastoma binding protein 8
chr6_-_42185603 1.493 NM_018141
MRPS10
mitochondrial ribosomal protein S10
chr11_+_17332454 1.469


chr1_+_161123510 1.469 NM_016406
UFC1
ubiquitin-fold modifier conjugating enzyme 1
chr7_+_94292816 1.464 PEG10
paternally expressed 10
chr17_+_61086897 1.456 NM_025185
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr7_-_99717463 1.439 NM_001190415
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr3_-_98241357 1.432 CLDND1
claudin domain containing 1
chr6_-_131321868 1.400 NM_001252660
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr1_-_151414641 1.394 NM_207171
POGZ
pogo transposable element with ZNF domain
chr1_-_51425829 1.363 FAF1
Fas (TNFRSF6) associated factor 1
chr3_-_52713728 1.358 NM_018165
NM_181042
PBRM1

polybromo 1

chr1_-_197552304 1.343 DENND1B
DENN/MADD domain containing 1B
chr2_-_242556883 1.342 NM_001164356
THAP4
THAP domain containing 4
chr1_+_210501595 1.328 NM_001122834
NM_001170564
HHAT

hedgehog acyltransferase

chr6_-_2840683 1.327 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr5_-_179044835 1.303 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr3_+_156394452 1.302 NM_001184718
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr12_-_121792011 1.302 NM_001137559
ANAPC5
anaphase promoting complex subunit 5
chr1_+_148558187 1.301 NM_001170755
NBPF15
neuroblastoma breakpoint family, member 15
chr11_+_129979330 1.249 APLP2
amyloid beta (A4) precursor-like protein 2
chr18_+_72166568 1.243 CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr10_+_91498724 1.240 KIF20B
kinesin family member 20B
chr19_+_17378148 1.219 NM_001033549
NM_014173
BABAM1

BRISC and BRCA1 A complex member 1

chr4_+_114214102 1.218 ANK2
ankyrin 2, neuronal
chr12_+_54410893 1.213 HOXC5
HOXC6
homeobox C5
homeobox C6
chr1_-_168106810 1.209 GPR161
G protein-coupled receptor 161
chr16_+_29471206 1.177 NM_001017390
NM_177552
SULT1A4
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr20_+_62795826 1.174 NM_004535
MYT1
myelin transcription factor 1
chr11_+_67376926 1.142 NDUFV1
NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
chr1_-_150669499 1.140 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr6_-_64029847 1.139 NM_001143940
NM_016571
LGSN

lengsin, lens protein with glutamine synthetase domain

chr3_+_130569368 1.129 NM_001199180
NM_001199181
NM_001199182
ATP2C1


ATPase, Ca++ transporting, type 2C, member 1


chr2_+_109271267 1.126 NM_001193485
LIMS1
LIM and senescent cell antigen-like domains 1
chr18_+_21032786 1.118 NM_003831
RIOK3
RIO kinase 3 (yeast)
chr4_+_170581212 1.112 NM_001243374
CLCN3
chloride channel 3
chr2_-_171923482 1.103 NM_001136555
TLK1
tousled-like kinase 1
chr11_-_47510518 1.089 NM_001025596
NM_001172640
CELF1

CUGBP, Elav-like family member 1

chr8_-_72268720 1.076 NM_172058
NM_172059
NM_172060
EYA1


eyes absent homolog 1 (Drosophila)


chr19_-_55767103 1.075 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr5_+_70944968 1.074 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr14_+_96722546 1.072 NM_000710
BDKRB1
bradykinin receptor B1
chr3_-_69037498 1.042 C3orf64
chromosome 3 open reading frame 64
chrX_-_10544852 1.030 NM_001193277
MID1
midline 1 (Opitz/BBB syndrome)
chr10_-_29923900 1.007 NM_021738
SVIL
supervillin
chr1_-_85741992 1.005 BCL10
B-cell CLL/lymphoma 10
chr2_-_216241321 0.997 FN1
fibronectin 1
chr7_+_76054251 0.988 NM_001110354
ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chr5_+_43609261 0.988 NNT
nicotinamide nucleotide transhydrogenase
chr22_+_20909221 0.958 MED15
mediator complex subunit 15
chr1_-_205601999 0.933 NM_001973
NM_021795
ELK4

ELK4, ETS-domain protein (SRF accessory protein 1)

chr3_-_126327397 0.923 NM_001039783
TXNRD3NB
thioredoxin reductase 3 neighbor
chr16_+_30210548 0.923 NM_001017390
NM_177552
SULT1A4
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr1_+_210001351 0.912 DIEXF
digestive organ expansion factor homolog (zebrafish)
chr18_-_43668132 0.910 ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr22_+_40573879 0.904 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr11_-_111750144 0.898 NM_138378
FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr1_+_35851101 0.897 ZMYM4
zinc finger, MYM-type 4
chr6_-_47254143 0.884 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chrX_+_54834107 0.858 NM_177433
MAGED2
melanoma antigen family D, 2
chr12_+_57828457 0.846 NM_005538
INHBC
inhibin, beta C
chr11_+_73882316 0.845 NM_016147
PPME1
protein phosphatase methylesterase 1
chr11_-_118900078 0.838 NM_001164280
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr3_+_184038050 0.833 NM_004953
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr17_+_75181294 0.830 NM_001144001
SEC14L1
SEC14-like 1 (S. cerevisiae)
chr3_+_49506079 0.826 NM_001177643
DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr6_+_52935770 0.820 NM_012347
FBXO9
F-box protein 9
chr1_+_151739130 0.820 NM_016178
OAZ3
ornithine decarboxylase antizyme 3
chr6_-_47253962 0.812 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr17_-_39197663 0.788 NM_030967
KRTAP1-3
KRTAP1-1
keratin associated protein 1-3
keratin associated protein 1-1
chrX_-_57164057 0.766 NM_019003
SPIN2A
spindlin family, member 2A
chr1_+_93300359 0.759 RPL5
ribosomal protein L5
chr15_+_49715374 0.759 NM_002009
FGF7
fibroblast growth factor 7
chr5_+_155753755 0.750 NM_000337
NM_001128209
NM_172244
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr1_-_103496768 0.744 COL11A1
collagen, type XI, alpha 1
chrX_-_10645726 0.728 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr5_+_161277702 0.725 NM_001127648
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr5_+_140560979 0.712 NM_020957
PCDHB16
protocadherin beta 16

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.30 2.41e-03 GO:0007049 cell cycle
1.62 2.52e-03 GO:0016043 cellular component organization
1.67 4.84e-03 GO:0048731 system development
1.57 7.16e-03 GO:0007275 multicellular organismal development
2.72 7.72e-03 GO:0000278 mitotic cell cycle
1.53 8.39e-03 GO:0032502 developmental process
1.56 9.39e-03 GO:0071840 cellular component organization or biogenesis
1.83 1.08e-02 GO:0048513 organ development
2.35 1.63e-02 GO:0022402 cell cycle process
1.40 1.79e-02 GO:0032501 multicellular organismal process
1.58 1.87e-02 GO:0048856 anatomical structure development
1.32 2.25e-02 GO:0050794 regulation of cellular process
42.94 2.73e-02 GO:0006828 manganese ion transport
1.29 3.46e-02 GO:0050789 regulation of biological process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.41 6.23e-09 GO:0005737 cytoplasm
1.65 5.31e-04 GO:0043234 protein complex
1.18 2.27e-03 GO:0044424 intracellular part
5.07 6.57e-03 GO:0044449 contractile fiber part
1.50 6.77e-03 GO:0032991 macromolecular complex
4.94 8.25e-03 GO:0030016 myofibril
4.66 1.36e-02 GO:0043292 contractile fiber
1.16 1.54e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.32 1.03e-03 GO:0005515 protein binding
42.94 6.07e-03 GO:0005384 manganese ion transmembrane transporter activity
2.56 1.09e-02 GO:0008092 cytoskeletal protein binding
2.92 3.85e-02 GO:0003779 actin binding
1.14 4.85e-02 GO:0005488 binding