Motif ID: ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Z-value: 3.162


Transcription factors associated with ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2:

Gene SymbolEntrez IDGene Name
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2
BHLHB2 8553 basic helix-loop-helix domain containing, class B, 2
MAX 4149 MYC associated factor X
MYC 4609 v-myc myelocytomatosis viral oncogene homolog (avian)
USF1 7391 upstream transcription factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYCchr8_+_1287483120.733.6e-38Click!
ARNT2chr15_+_80696569-0.491.2e-14Click!
MAXchr14_-_655690560.261.0e-04Click!
ARNTchr1_-_150849211-0.228.5e-04Click!
BHLHE40chr3_+_5021141-0.126.7e-02Click!


Activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2.

activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2


Sorted Z-values histogram for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Sorted Z-values for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_58146108 302.760 CDK4
cyclin-dependent kinase 4
chr12_-_58146110 299.674 CDK4
cyclin-dependent kinase 4
chr12_-_58146025 299.008 CDK4
cyclin-dependent kinase 4
chr12_-_58146118 271.636 NM_000075
CDK4
cyclin-dependent kinase 4
chr2_-_10588451 157.598 NM_002539
ODC1
ornithine decarboxylase 1
chr14_+_20923341 135.218 APEX1
APEX nuclease (multifunctional DNA repair enzyme) 1
chr8_+_98656428 112.966 MTDH
metadherin
chr2_+_216176818 104.570 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr14_+_20923289 102.646 NM_001244249
NM_001641
NM_080648
NM_080649
APEX1



APEX nuclease (multifunctional DNA repair enzyme) 1



chr19_+_10765106 101.532 ILF3
interleukin enhancer binding factor 3, 90kDa
chr2_+_216176808 101.483 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr8_+_98656329 101.007 NM_178812
MTDH
metadherin
chr1_-_26232890 99.249 NM_001145454
NM_005563
STMN1

stathmin 1

chr8_+_98656494 95.044 MTDH
metadherin
chr3_+_158519911 92.531 MFSD1
major facilitator superfamily domain containing 1
chr14_+_20923705 90.389 APEX1
APEX nuclease (multifunctional DNA repair enzyme) 1
chr4_-_100871431 89.802 H2AFZ
H2A histone family, member Z
chr3_+_158519888 88.588 MFSD1
major facilitator superfamily domain containing 1
chr6_-_43197178 82.437 NM_006443
NM_199184
C6orf108

chromosome 6 open reading frame 108

chr17_+_49337882 81.503 UTP18
UTP18 small subunit (SSU) processome component homolog (yeast)
chr17_+_49337892 80.759 NM_016001
UTP18
UTP18 small subunit (SSU) processome component homolog (yeast)
chr14_+_20923364 78.719 APEX1
APEX nuclease (multifunctional DNA repair enzyme) 1
chrX_+_100663205 78.387 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr2_+_113403433 77.558 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr17_+_49337909 76.232 UTP18
UTP18 small subunit (SSU) processome component homolog (yeast)
chr6_+_160390128 75.632 NM_000876
IGF2R
insulin-like growth factor 2 receptor
chr1_+_44440642 75.591 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr4_-_100871482 75.078 NM_002106
H2AFZ
H2A histone family, member Z
chr11_-_64014381 73.952 PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr6_-_109703661 71.100 CD164
CD164 molecule, sialomucin
chr3_-_112280764 71.043 ATG3
ATG3 autophagy related 3 homolog (S. cerevisiae)
chr17_+_49230954 70.476 NME1
NME1-NME2
non-metastatic cells 1, protein (NM23A) expressed in
NME1-NME2 readthrough
chr3_+_127317271 70.199 MCM2
minichromosome maintenance complex component 2
chrX_-_100662905 69.660 NM_000169
GLA
galactosidase, alpha
chr7_-_99698993 69.204 MCM7
minichromosome maintenance complex component 7
chr11_-_64014264 69.109 PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr11_-_64014407 68.466 NM_138689
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr3_+_127317274 68.300 MCM2
minichromosome maintenance complex component 2
chr7_-_99699030 67.218 MCM7
minichromosome maintenance complex component 7
chr1_+_44440623 66.928 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr10_+_124913884 66.616 BUB3
budding uninhibited by benzimidazoles 3 homolog (yeast)
chr1_+_44440673 66.191 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr19_+_49458151 65.819 BAX
BCL2-associated X protein
chrX_+_100663229 65.605 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr6_+_36562135 65.365 SRSF3
serine/arginine-rich splicing factor 3
chr4_-_99850280 64.969 EIF4E
eukaryotic translation initiation factor 4E
chrX_-_100662788 64.504 GLA
galactosidase, alpha
chr2_+_109204745 64.180 NM_004987
LIMS1
LIM and senescent cell antigen-like domains 1
chr1_+_44440595 63.654 NM_001039457
NM_004047
ATP6V0B

ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b

chr3_+_158519877 63.042 MFSD1
major facilitator superfamily domain containing 1
chr20_+_44519965 62.977 CTSA
cathepsin A
chr17_+_49230929 62.832 NME1
non-metastatic cells 1, protein (NM23A) expressed in
chr3_+_158519714 62.508 NM_001167903
NM_022736
MFSD1

major facilitator superfamily domain containing 1

chr20_+_44520021 62.296 CTSA
cathepsin A
chr19_+_50180408 62.090 NM_001207042
NM_001536
NM_198318
PRMT1


protein arginine methyltransferase 1


chr3_+_127317212 61.663 NM_004526
MCM2
minichromosome maintenance complex component 2
chr1_-_154531083 60.731 NM_017582
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr2_+_27440342 60.204 CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr1_-_115259381 60.193 NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr1_-_26233367 59.878 NM_203399
STMN1
stathmin 1
chr11_-_64014140 59.732 PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr2_-_10588273 59.661 ODC1
ornithine decarboxylase 1
chr4_-_100871418 59.539 H2AFZ
H2A histone family, member Z
chr17_+_49244082 59.283 NM_001018138
NME2
non-metastatic cells 2, protein (NM23B) expressed in
chr17_+_46970128 58.691 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr19_+_47634118 58.542 SAE1
SUMO1 activating enzyme subunit 1
chr7_-_99698916 58.318 MCM7
minichromosome maintenance complex component 7
chr11_+_61560108 58.141 NM_004111
FEN1
flap structure-specific endonuclease 1
chr20_+_44519924 57.885 CTSA
cathepsin A
chr10_+_75936524 57.681 ADK
adenosine kinase
chr4_+_57301898 57.605 NM_006452
PAICS
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr19_+_47634133 57.553 SAE1
SUMO1 activating enzyme subunit 1
chr21_-_46237978 56.375 SUMO3
SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
chr10_+_75936546 56.238 ADK
adenosine kinase
chr19_+_8509869 55.934 HNRNPM
heterogeneous nuclear ribonucleoprotein M
chr4_+_57302448 55.869 PAICS
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr19_+_49458031 55.708 NM_004324
NM_138761
NM_138763
NM_138764
BAX



BCL2-associated X protein



chr9_-_34048887 55.706 NM_018449
UBAP2
ubiquitin associated protein 2
chr3_+_158519925 55.331 MFSD1
major facilitator superfamily domain containing 1
chr11_-_47664014 55.318 NM_014342
MTCH2
mitochondrial carrier 2
chr6_-_7313352 55.063 NM_003144
SSR1
signal sequence receptor, alpha
chr2_-_198364560 55.036 HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr10_+_75936220 54.952 NM_001123
NM_001202449
ADK

adenosine kinase

chr19_+_49458129 54.401 BAX
BCL2-associated X protein
chr16_+_88923490 53.961 NM_016209
TRAPPC2L
trafficking protein particle complex 2-like
chr8_+_55047780 53.590 NM_014175
MRPL15
mitochondrial ribosomal protein L15
chr2_-_198364522 52.295 HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr15_+_44084517 52.289 NM_001199878
SERF2-C15ORF63
SERF2
SERF2-C15orf63 readthrough
small EDRK-rich factor 2
chr6_-_109703703 51.680 NM_001142401
NM_001142402
NM_001142403
NM_001142404
NM_006016
CD164




CD164 molecule, sialomucin




chr6_-_33385814 51.059


chr2_-_198364623 51.031 NM_002156
HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr2_+_216176678 50.841 NM_004044
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr19_+_47634148 50.625 SAE1
SUMO1 activating enzyme subunit 1
chr12_-_2986299 50.278 NM_001243088
NM_001243089
NM_021953
NM_202002
NM_202003
FOXM1




forkhead box M1




chr1_-_27226928 50.132 GPATCH3
G patch domain containing 3
chr4_-_47465719 49.897 COMMD8
COMM domain containing 8
chr21_-_46237974 49.727 SUMO3
SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
chr10_-_120840311 49.296 NM_003750
EIF3A
eukaryotic translation initiation factor 3, subunit A
chr6_+_36562139 48.625 SRSF3
serine/arginine-rich splicing factor 3
chr19_+_8509802 48.593 NM_005968
NM_031203
HNRNPM

heterogeneous nuclear ribonucleoprotein M

chr4_-_47465646 47.263 NM_017845
COMMD8
COMM domain containing 8
chr12_+_104359557 46.627 NM_003211
TDG
thymine-DNA glycosylase
chr10_+_124913759 46.572 NM_001007793
NM_004725
BUB3

budding uninhibited by benzimidazoles 3 homolog (yeast)

chr12_-_76953561 46.531 NM_001003712
NM_020841
OSBPL8

oxysterol binding protein-like 8

chr10_-_120840296 46.487 EIF3A
eukaryotic translation initiation factor 3, subunit A
chr19_+_797390 45.881 NM_002819
NM_031990
NM_031991
NM_175847
PTBP1



polypyrimidine tract binding protein 1



chr6_-_8102753 45.762 NM_001135650
NM_004280
EEF1E1

eukaryotic translation elongation factor 1 epsilon 1

chr17_+_49230896 45.718 NM_000269
NM_198175
NM_001018136
NME1

NME1-NME2
non-metastatic cells 1, protein (NM23A) expressed in

NME1-NME2 readthrough
chr12_-_2986095 45.653 FOXM1
forkhead box M1
chr18_+_77866914 45.448 NM_014913
ADNP2
ADNP homeobox 2
chr1_+_214776494 44.989 NM_016343
CENPF
centromere protein F, 350/400kDa (mitosin)
chr1_-_154600446 44.984 NM_001025107
ADAR
adenosine deaminase, RNA-specific
chr1_-_11120081 44.540 NM_003132
SRM
spermidine synthase
chr1_-_183604885 44.270 NM_005717
ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr6_-_33386064 44.253 NM_001014433
NM_001014837
NM_001014838
NM_001014840
NM_015921
CUTA




cutA divalent cation tolerance homolog (E. coli)




chr1_-_183604850 43.936 ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr10_+_75936443 43.875 ADK
adenosine kinase
chr17_+_49230938 43.163 NME1
NME1-NME2
non-metastatic cells 1, protein (NM23A) expressed in
NME1-NME2 readthrough
chr5_+_133707105 43.079 UBE2B
ubiquitin-conjugating enzyme E2B
chr1_-_154600383 43.037 ADAR
adenosine deaminase, RNA-specific
chr1_+_43148359 42.717 YBX1
Y box binding protein 1
chr8_-_104427373 42.648 NM_030780
SLC25A32
solute carrier family 25, member 32
chr11_+_61560352 42.614 FEN1
flap structure-specific endonuclease 1
chr3_-_49066760 41.621 IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr10_+_124913921 41.544 BUB3
budding uninhibited by benzimidazoles 3 homolog (yeast)
chr4_-_99850242 41.168 NM_001130678
EIF4E
eukaryotic translation initiation factor 4E
chr1_+_154193757 40.875 UBAP2L
ubiquitin associated protein 2-like
chr19_-_5720155 40.780 LONP1
lon peptidase 1, mitochondrial
chr1_-_26232643 40.282 NM_203401
STMN1
stathmin 1
chr1_-_115259433 40.246 NM_002524
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr6_+_34204647 39.770 NM_145901
NM_145902
HMGA1

high mobility group AT-hook 1

chrX_+_23685613 39.561 PRDX4
peroxiredoxin 4
chr19_+_47634044 39.470 NM_001145713
NM_001145714
NM_005500
SAE1


SUMO1 activating enzyme subunit 1


chr6_-_109703617 39.291 CD164
CD164 molecule, sialomucin
chr19_+_50180492 39.091 PRMT1
protein arginine methyltransferase 1
chr6_-_109703553 38.957 CD164
CD164 molecule, sialomucin
chr5_+_68530621 38.891 NM_001799
CDK7
cyclin-dependent kinase 7
chr9_-_116172658 38.855 POLE3
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr3_-_113465101 38.786 NM_025146
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr21_-_46237966 38.776 SUMO3
SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
chr19_+_13049413 38.549 NM_004343
CALR
calreticulin
chr2_-_44223039 38.448 LRPPRC
leucine-rich PPR-motif containing
chr17_-_5342380 38.332 C1QBP
complement component 1, q subcomponent binding protein
chr18_+_158480 38.208 NM_001037334
NM_005151
USP14

ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)

chrX_+_23685658 37.928 PRDX4
peroxiredoxin 4
chr2_-_61764661 37.658 XPO1
exportin 1 (CRM1 homolog, yeast)
chr12_+_132413776 37.567 NM_001002019
NM_025215
PUS1

pseudouridylate synthase 1

chr21_-_38445389 37.537 NM_153682
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr1_-_11120047 37.480 SRM
spermidine synthase
chr19_-_2427874 37.408 NM_012458
TIMM13
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr8_+_98788014 37.365 LAPTM4B
lysosomal protein transmembrane 4 beta
chrX_+_23685637 37.297 NM_006406
PRDX4
peroxiredoxin 4
chr19_+_12848281 37.047 NM_004317
ASNA1
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr11_+_18344113 37.004 GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr22_+_20105145 36.922 RANBP1
RAN binding protein 1
chr6_+_36562089 36.741 NM_003017
SRSF3
serine/arginine-rich splicing factor 3
chr2_-_44223131 36.704 NM_133259
LRPPRC
leucine-rich PPR-motif containing
chr1_-_78148326 36.659 NM_015534
ZZZ3
zinc finger, ZZ-type containing 3
chr1_+_33116748 36.441 NM_001135255
NM_005610
NM_001135256
RBBP4


retinoblastoma binding protein 4


chr5_+_68530713 36.297 CDK7
cyclin-dependent kinase 7
chr2_-_44223112 35.861 LRPPRC
leucine-rich PPR-motif containing
chr19_-_5720136 35.688 LONP1
lon peptidase 1, mitochondrial
chr16_+_31044414 35.513 STX4
syntaxin 4
chr1_+_111992105 35.268 ATP5F1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr6_-_28891409 35.237 TRIM27
tripartite motif containing 27
chrX_+_100663120 35.164 NM_001032393
NM_019597
HNRNPH2

heterogeneous nuclear ribonucleoprotein H2 (H')

chr2_-_26101301 34.818 NM_018263
ASXL2
additional sex combs like 2 (Drosophila)
chr10_+_22605300 34.791 NM_001204062
NM_012071
COMMD3-BMI1
COMMD3
COMMD3-BMI1 readthrough
COMM domain containing 3
chr1_+_214776582 34.781 CENPF
centromere protein F, 350/400kDa (mitosin)
chr7_-_132766834 34.712 CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr5_-_137911039 34.697 HSPA9
heat shock 70kDa protein 9 (mortalin)
chr12_+_49658862 34.534 NM_032704
TUBA1C
tubulin, alpha 1c
chr19_-_13227212 34.502 NM_001142554
NM_017722
NM_001136035
TRMT1


TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)


chr12_-_65153189 34.500 NM_002076
GNS
glucosamine (N-acetyl)-6-sulfatase
chr10_+_124913862 34.354 BUB3
budding uninhibited by benzimidazoles 3 homolog (yeast)
chr19_+_8509594 34.184 HNRNPM
heterogeneous nuclear ribonucleoprotein M
chr12_-_76953259 34.129 OSBPL8
oxysterol binding protein-like 8
chr1_+_45477888 34.128 UROD
uroporphyrinogen decarboxylase
chr8_+_22224758 34.107 NM_001128431
NM_001135154
NM_015359
SLC39A14


solute carrier family 39 (zinc transporter), member 14


chr12_+_49658865 34.061 TUBA1C
tubulin, alpha 1c
chr20_+_44520203 33.979 CTSA
cathepsin A
chr1_-_183604793 33.942 ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr7_-_132766697 33.879 NM_017812
CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr2_+_109204777 33.789 LIMS1
LIM and senescent cell antigen-like domains 1
chr9_-_116172635 33.664 POLE3
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr7_+_150759633 33.644 NM_001199693
NM_001199694
SLC4A2

solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)

chr12_-_49318663 33.450 NM_001143781
FKBP11
FK506 binding protein 11, 19 kDa
chr13_+_76123885 33.444 NM_006002
UCHL3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr21_-_45196200 33.344 NM_000100
CSTB
cystatin B (stefin B)
chr3_-_112280359 33.301 NM_022488
ATG3
ATG3 autophagy related 3 homolog (S. cerevisiae)
chr19_-_42806928 33.202 NM_001145939
NM_001145940
PAFAH1B3

platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)

chr1_-_155232091 33.040 NM_005698
NM_052837
SCAMP3

secretory carrier membrane protein 3

chr6_-_114292312 33.029 NM_001527
HDAC2
histone deacetylase 2
chr8_-_126103873 33.001 KIAA0196
KIAA0196
chr11_+_8008866 32.836 NM_003754
EIF3F
eukaryotic translation initiation factor 3, subunit F
chr2_+_178077421 32.836 NM_194247
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3
chr19_+_41256758 32.794 NM_004596
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr8_-_104427268 32.706 SLC25A32
solute carrier family 25, member 32
chr7_-_99699426 32.660 NM_005916
MCM7
minichromosome maintenance complex component 7
chr18_+_158586 32.587 USP14
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.88 4.33e-31 GO:0034641 cellular nitrogen compound metabolic process
1.52 1.67e-30 GO:0044237 cellular metabolic process
1.84 1.22e-29 GO:0006807 nitrogen compound metabolic process
1.94 1.75e-29 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.47 1.58e-25 GO:0044238 primary metabolic process
1.42 5.58e-25 GO:0008152 metabolic process
1.23 1.60e-22 GO:0009987 cellular process
1.59 4.79e-22 GO:0044260 cellular macromolecule metabolic process
1.87 3.88e-19 GO:0090304 nucleic acid metabolic process
1.48 1.20e-17 GO:0043170 macromolecule metabolic process
1.71 5.66e-14 GO:0044249 cellular biosynthetic process
1.81 2.88e-13 GO:0010467 gene expression
1.66 1.28e-12 GO:0009058 biosynthetic process
1.81 4.25e-12 GO:0016070 RNA metabolic process
1.69 4.87e-09 GO:0044281 small molecule metabolic process
1.45 7.99e-09 GO:0071840 cellular component organization or biogenesis
2.89 8.14e-09 GO:0006412 translation
2.25 8.26e-09 GO:0006396 RNA processing
1.56 9.93e-09 GO:0044267 cellular protein metabolic process
1.52 2.09e-08 GO:0071841 cellular component organization or biogenesis at cellular level
2.08 2.22e-08 GO:0046907 intracellular transport
2.29 5.25e-08 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.67 1.71e-07 GO:0034645 cellular macromolecule biosynthetic process
1.65 4.21e-07 GO:0009059 macromolecule biosynthetic process
1.81 4.31e-07 GO:0044248 cellular catabolic process
2.28 5.82e-07 GO:0006753 nucleoside phosphate metabolic process
2.28 5.82e-07 GO:0009117 nucleotide metabolic process
1.75 9.38e-07 GO:0051641 cellular localization
2.52 9.79e-07 GO:0044419 interspecies interaction between organisms
1.69 1.12e-06 GO:0009056 catabolic process
2.07 1.56e-06 GO:0046483 heterocycle metabolic process
2.14 1.60e-06 GO:0006259 DNA metabolic process
1.41 1.84e-06 GO:0016043 cellular component organization
1.79 2.53e-06 GO:0051649 establishment of localization in cell
2.18 4.17e-06 GO:0044265 cellular macromolecule catabolic process
1.70 4.93e-06 GO:0033036 macromolecule localization
2.16 6.39e-06 GO:0016071 mRNA metabolic process
2.98 7.88e-06 GO:0000375 RNA splicing, via transesterification reactions
1.45 9.63e-06 GO:0071842 cellular component organization at cellular level
1.60 1.08e-05 GO:0006996 organelle organization
2.05 1.09e-05 GO:0009057 macromolecule catabolic process
2.31 1.27e-05 GO:0016032 viral reproduction
3.21 1.48e-05 GO:0022415 viral reproductive process
1.71 2.16e-05 GO:0044085 cellular component biogenesis
2.17 2.18e-05 GO:0034621 cellular macromolecular complex subunit organization
3.38 2.38e-05 GO:0019058 viral infectious cycle
1.40 3.06e-05 GO:0019538 protein metabolic process
2.02 5.47e-05 GO:0071822 protein complex subunit organization
2.92 5.50e-05 GO:0022411 cellular component disassembly
2.92 5.50e-05 GO:0071845 cellular component disassembly at cellular level
3.74 6.70e-05 GO:0006414 translational elongation
2.27 7.78e-05 GO:0006397 mRNA processing
1.82 9.39e-05 GO:0033554 cellular response to stress
2.20 9.77e-05 GO:0072521 purine-containing compound metabolic process
2.27 1.45e-04 GO:0044271 cellular nitrogen compound biosynthetic process
2.80 1.64e-04 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.80 1.64e-04 GO:0000398 nuclear mRNA splicing, via spliceosome
2.06 2.41e-04 GO:0044283 small molecule biosynthetic process
1.79 2.56e-04 GO:0043933 macromolecular complex subunit organization
1.69 2.74e-04 GO:0008104 protein localization
2.77 3.22e-04 GO:0034404 nucleobase, nucleoside and nucleotide biosynthetic process
2.77 3.22e-04 GO:0034654 nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process
3.43 3.79e-04 GO:0032984 macromolecular complex disassembly
3.43 3.79e-04 GO:0034623 cellular macromolecular complex disassembly
2.36 4.50e-04 GO:0008380 RNA splicing
2.27 5.06e-04 GO:0006520 cellular amino acid metabolic process
2.58 5.11e-04 GO:0051186 cofactor metabolic process
1.76 6.00e-04 GO:0015031 protein transport
2.28 6.30e-04 GO:0009259 ribonucleotide metabolic process
1.75 6.67e-04 GO:0045184 establishment of protein localization
3.16 1.00e-03 GO:0042254 ribosome biogenesis
2.48 1.40e-03 GO:0018130 heterocycle biosynthetic process
2.75 1.45e-03 GO:0006732 coenzyme metabolic process
2.08 1.63e-03 GO:0044106 cellular amine metabolic process
1.35 1.91e-03 GO:0006810 transport
3.11 2.39e-03 GO:0050657 nucleic acid transport
3.11 2.39e-03 GO:0050658 RNA transport
3.11 2.39e-03 GO:0051236 establishment of RNA localization
2.69 2.40e-03 GO:0051169 nuclear transport
2.59 2.41e-03 GO:0006457 protein folding
5.85 2.46e-03 GO:0015682 ferric iron transport
5.85 2.46e-03 GO:0033572 transferrin transport
1.34 2.66e-03 GO:0051234 establishment of localization
2.91 2.98e-03 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
3.25 3.27e-03 GO:0009260 ribonucleotide biosynthetic process
3.36 3.42e-03 GO:0043241 protein complex disassembly
3.36 3.42e-03 GO:0043624 cellular protein complex disassembly
2.31 3.82e-03 GO:0034660 ncRNA metabolic process
3.01 4.39e-03 GO:0006403 RNA localization
6.13 4.60e-03 GO:0009156 ribonucleoside monophosphate biosynthetic process
2.28 5.56e-03 GO:0010608 posttranscriptional regulation of gene expression
2.63 5.91e-03 GO:0006913 nucleocytoplasmic transport
1.29 6.94e-03 GO:0051179 localization
1.90 7.19e-03 GO:0006974 response to DNA damage stimulus
3.10 7.29e-03 GO:0051028 mRNA transport
2.08 7.54e-03 GO:0030163 protein catabolic process
2.04 7.59e-03 GO:0006163 purine nucleotide metabolic process
1.65 7.63e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.66 7.80e-03 GO:0051704 multi-organism process
2.81 8.92e-03 GO:0072522 purine-containing compound biosynthetic process
2.68 9.47e-03 GO:0043623 cellular protein complex assembly
4.14 9.90e-03 GO:0009112 nucleobase metabolic process
5.16 1.02e-02 GO:0006144 purine base metabolic process
1.59 1.32e-02 GO:0007049 cell cycle
1.88 1.38e-02 GO:0009308 amine metabolic process
5.50 1.46e-02 GO:0009161 ribonucleoside monophosphate metabolic process
2.08 1.75e-02 GO:0044257 cellular protein catabolic process
5.32 2.07e-02 GO:0015988 energy coupled proton transport, against electrochemical gradient
5.32 2.07e-02 GO:0015991 ATP hydrolysis coupled proton transport
2.09 2.36e-02 GO:0009150 purine ribonucleotide metabolic process
2.07 2.38e-02 GO:0071495 cellular response to endogenous stimulus
2.54 2.43e-02 GO:0009165 nucleotide biosynthetic process
2.07 2.57e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
3.31 2.58e-02 GO:0009116 nucleoside metabolic process
2.46 3.09e-02 GO:0006260 DNA replication
2.52 4.12e-02 GO:0006417 regulation of translation
3.31 4.51e-02 GO:0006839 mitochondrial transport
1.55 4.53e-02 GO:0022607 cellular component assembly
1.56 4.79e-02 GO:0009892 negative regulation of metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.29 2.14e-39 GO:0044424 intracellular part
1.26 3.53e-36 GO:0005622 intracellular
1.39 2.02e-31 GO:0005737 cytoplasm
1.57 2.16e-31 GO:0044446 intracellular organelle part
2.04 3.46e-31 GO:0031974 membrane-enclosed lumen
1.55 1.24e-30 GO:0044422 organelle part
2.02 4.11e-29 GO:0043233 organelle lumen
2.03 6.06e-29 GO:0070013 intracellular organelle lumen
2.01 8.17e-27 GO:0044428 nuclear part
1.34 3.00e-26 GO:0043227 membrane-bounded organelle
1.33 4.17e-26 GO:0043231 intracellular membrane-bounded organelle
1.29 6.06e-25 GO:0043226 organelle
1.29 6.33e-25 GO:0043229 intracellular organelle
2.03 6.65e-23 GO:0031981 nuclear lumen
1.43 1.47e-20 GO:0044444 cytoplasmic part
1.43 2.91e-18 GO:0005634 nucleus
2.84 4.64e-16 GO:0005730 nucleolus
1.56 5.93e-16 GO:0032991 macromolecular complex
2.03 1.59e-15 GO:0005654 nucleoplasm
1.76 1.31e-14 GO:0005829 cytosol
2.61 7.11e-13 GO:0030529 ribonucleoprotein complex
2.22 8.97e-11 GO:0031967 organelle envelope
2.18 2.58e-10 GO:0031975 envelope
1.48 4.45e-08 GO:0043228 non-membrane-bounded organelle
1.48 4.45e-08 GO:0043232 intracellular non-membrane-bounded organelle
1.45 5.06e-08 GO:0043234 protein complex
9.75 4.76e-07 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
1.68 6.60e-07 GO:0005739 mitochondrion
2.01 6.79e-07 GO:0044429 mitochondrial part
1.07 8.09e-07 GO:0044464 cell part
1.07 8.36e-07 GO:0005623 cell
2.21 1.65e-06 GO:0005740 mitochondrial envelope
2.20 5.05e-06 GO:0031966 mitochondrial membrane
1.91 5.77e-06 GO:0044451 nucleoplasm part
2.36 1.04e-05 GO:0019866 organelle inner membrane
2.30 1.07e-04 GO:0005743 mitochondrial inner membrane
2.55 1.19e-04 GO:0016604 nuclear body
7.18 5.19e-04 GO:0033176 proton-transporting V-type ATPase complex
1.40 7.52e-04 GO:0031090 organelle membrane
3.41 8.25e-04 GO:0042470 melanosome
3.41 8.25e-04 GO:0048770 pigment granule
4.45 3.48e-03 GO:0016469 proton-transporting two-sector ATPase complex
8.70 8.41e-03 GO:0005744 mitochondrial inner membrane presequence translocase complex
2.17 1.16e-02 GO:0005635 nuclear envelope
2.62 1.20e-02 GO:0005681 spliceosomal complex
1.71 2.63e-02 GO:0005694 chromosome
8.86 3.90e-02 GO:0016281 eukaryotic translation initiation factor 4F complex
8.86 3.90e-02 GO:0033180 proton-transporting V-type ATPase, V1 domain

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.47 1.49e-34 GO:0005515 protein binding
2.36 1.70e-15 GO:0003723 RNA binding
1.17 2.80e-15 GO:0005488 binding
3.74 2.68e-04 GO:0008135 translation factor activity, nucleic acid binding
1.40 2.87e-04 GO:0000166 nucleotide binding
1.31 5.43e-04 GO:0003676 nucleic acid binding
1.92 2.24e-03 GO:0016874 ligase activity
5.70 2.52e-03 GO:0003727 single-stranded RNA binding
7.09 3.48e-03 GO:0046961 proton-transporting ATPase activity, rotational mechanism
1.20 5.28e-03 GO:0003824 catalytic activity
2.09 7.98e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
6.38 8.95e-03 GO:0003746 translation elongation factor activity
4.78 3.76e-02 GO:0019829 cation-transporting ATPase activity
3.11 4.47e-02 GO:0003729 mRNA binding