Motif ID: BPTF.p2

Z-value: 2.079


Transcription factors associated with BPTF.p2:

Gene SymbolEntrez IDGene Name
BPTF 2186 bromodomain PHD finger transcription factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
BPTFchr17_+_65822206,
chr17_+_65822242
0.483.2e-14Click!


Activity profile for motif BPTF.p2.

activity profile for motif BPTF.p2


Sorted Z-values histogram for motif BPTF.p2

Sorted Z-values for motif BPTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of BPTF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_216176678 64.286 NM_004044
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr11_-_77348758 56.345 NM_001293
CLNS1A
chloride channel, nucleotide-sensitive, 1A
chr11_-_67450536 47.447 RPL37
ribosomal protein L37
chr2_+_216176808 44.223 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr15_-_72501017 43.772 PKM2
pyruvate kinase, muscle
chr15_-_76603806 42.914 NM_000126
NM_001127716
ETFA

electron-transfer-flavoprotein, alpha polypeptide

chr14_+_67656109 40.658 NM_173526
FAM71D
family with sequence similarity 71, member D
chr5_+_132428394 39.286 HSPA4
heat shock 70kDa protein 4
chr21_+_30400229 37.346 USP16
ubiquitin specific peptidase 16
chr10_-_98321823 34.794 TM9SF3
transmembrane 9 superfamily member 3
chr7_+_56019552 34.721 NM_015969
MRPS17
mitochondrial ribosomal protein S17
chr13_+_37574916 34.417 EXOSC8
exosome component 8
chr6_-_30712294 33.860 NM_003897
IER3
immediate early response 3
chr12_-_58146118 33.721 NM_000075
CDK4
cyclin-dependent kinase 4
chr15_-_76603791 33.659 ETFA
electron-transfer-flavoprotein, alpha polypeptide
chr2_+_85804689 32.583 VAMP8
vesicle-associated membrane protein 8 (endobrevin)
chrX_+_123234462 32.509 STAG2
stromal antigen 2
chr9_+_75766794 32.227 ANXA1
annexin A1
chr14_+_102276125 32.221 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr10_-_98336445 30.816 TM9SF3
transmembrane 9 superfamily member 3
chr12_+_104680712 30.736 NM_003330
NM_182729
NM_182742
NM_182743
TXNRD1



thioredoxin reductase 1



chr9_+_75766777 30.328 NM_000700
ANXA1
annexin A1
chr17_-_1248346 30.278 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr16_+_28699878 29.902 NM_001199142
EIF3C
eukaryotic translation initiation factor 3, subunit C
chr1_-_154580632 29.469 ADAR
adenosine deaminase, RNA-specific
chr12_-_121792011 28.506 NM_001137559
ANAPC5
anaphase promoting complex subunit 5
chr12_-_46633551 27.202 SLC38A1
solute carrier family 38, member 1
chr19_-_13068008 26.983 GADD45GIP1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr19_+_10362598 26.933 NM_015956
NM_146387
NM_146388
MRPL4


mitochondrial ribosomal protein L4


chr8_+_42249383 26.901 VDAC3
voltage-dependent anion channel 3
chr3_+_171757413 26.886 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr13_-_37679800 26.824 NM_145203
CSNK1A1L
casein kinase 1, alpha 1-like
chr19_+_47634118 26.787 SAE1
SUMO1 activating enzyme subunit 1
chr13_+_37574677 26.475 NM_181503
EXOSC8
exosome component 8
chr2_-_152146373 26.265 NM_004688
NMI
N-myc (and STAT) interactor
chr12_-_57146081 26.243 NM_000946
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr19_+_47634044 26.090 NM_001145713
NM_001145714
NM_005500
SAE1


SUMO1 activating enzyme subunit 1


chr2_+_85804613 25.913 NM_003761
VAMP8
vesicle-associated membrane protein 8 (endobrevin)
chr11_-_47664014 25.607 NM_014342
MTCH2
mitochondrial carrier 2
chr12_-_110888152 25.238 NM_005719
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr15_+_59397276 25.216 NM_004701
CCNB2
cyclin B2
chr15_+_57511616 25.207 NM_207040
TCF12
transcription factor 12
chr1_+_223889253 25.124 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr1_+_93297614 25.022 RPL5
ribosomal protein L5
chr7_-_16844606 24.910 NM_006408
AGR2
anterior gradient 2 homolog (Xenopus laevis)
chr12_+_118454505 24.589 NM_001130112
NM_001206801
NM_007370
NM_181578
RFC5



replication factor C (activator 1) 5, 36.5kDa



chr9_-_36276930 24.466 NM_001128227
NM_001190388
GNE

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chr12_+_93861265 24.321 NM_014050
NM_172177
MRPL42

mitochondrial ribosomal protein L42

chr20_+_361675 24.308 TRIB3
tribbles homolog 3 (Drosophila)
chr2_+_201756639 24.170 NM_001142356
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr1_+_93297598 23.966 RPL5
ribosomal protein L5
chr2_+_216176818 23.903 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr1_+_46016524 23.752 AKR1A1
aldo-keto reductase family 1, member A1 (aldehyde reductase)
chr1_+_46016454 23.589 NM_001202413
NM_001202414
NM_006066
NM_153326
AKR1A1



aldo-keto reductase family 1, member A1 (aldehyde reductase)



chr20_+_3776385 23.439 NM_004358
NM_021872
NM_021873
CDC25B


cell division cycle 25 homolog B (S. pombe)


chr6_-_150057659 22.802 NUP43
nucleoporin 43kDa
chr2_-_47134945 22.734 MCFD2
multiple coagulation factor deficiency 2
chr5_-_176836488 22.028 F12
coagulation factor XII (Hageman factor)
chr2_+_86426555 21.909 NM_016622
NM_145644
MRPL35

mitochondrial ribosomal protein L35

chrX_-_102942968 21.893 NM_001142419
NM_001142420
NM_001142421
NM_001142422
NM_001142427
NM_001142428
NM_001142431
NM_001142432
MORF4L2







mortality factor 4 like 2







chr2_-_232326394 21.891 NCL
nucleolin
chr12_+_108079516 21.864 NM_007062
PWP1
PWP1 homolog (S. cerevisiae)
chr1_+_93297532 21.720 NM_000969
RPL5
ribosomal protein L5
chr2_+_3622895 21.676 RPS7
ribosomal protein S7
chr5_+_65372744 21.522 ERBB2IP
erbb2 interacting protein
chr11_-_58343308 21.410 NM_004811
LPXN
leupaxin
chr19_+_41768368 21.395 NM_144732
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr12_-_102512277 21.349 NM_024057
NUP37
nucleoporin 37kDa
chr6_+_24775154 21.250 NM_001251989
NM_001251990
NM_015895
GMNN


geminin, DNA replication inhibitor


chr16_-_58768132 21.215 NM_002080
GOT2
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
chr2_+_3622909 21.058 RPS7
ribosomal protein S7
chr12_-_110888160 21.040 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr13_-_37573474 20.942 NM_001142364
NM_013338
ALG5

asparagine-linked glycosylation 5, dolichyl-phosphate beta-glucosyltransferase homolog (S. cerevisiae)

chr6_-_38670829 20.610 GLO1
glyoxalase I
chr2_-_62115744 20.580 NM_006430
CCT4
chaperonin containing TCP1, subunit 4 (delta)
chr11_+_107992252 20.558 NM_000019
ACAT1
acetyl-CoA acetyltransferase 1
chr2_+_3622846 20.457 NM_001011
RPS7
ribosomal protein S7
chr9_+_79968344 20.435 VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr19_-_13068033 20.426 NM_052850
GADD45GIP1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr19_-_51858041 20.384 NM_001014763
ETFB
electron-transfer-flavoprotein, beta polypeptide
chrX_+_24073060 20.345 NM_001415
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chrX_+_24073071 20.063 EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr18_-_55289026 20.013 NM_004539
NARS
asparaginyl-tRNA synthetase
chr2_-_62115714 19.910 CCT4
chaperonin containing TCP1, subunit 4 (delta)
chr9_-_116172951 19.663 NM_017443
POLE3
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr7_+_55433140 19.486 NM_018697
LANCL2
LanC lantibiotic synthetase component C-like 2 (bacterial)
chr5_+_34687663 19.419 NM_001145523
RAI14
retinoic acid induced 14
chr3_+_183892668 19.373 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr4_+_146031528 19.353 ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr15_+_89787226 19.295 FANCI
Fanconi anemia, complementation group I
chr14_+_54863672 19.271 NM_001130851
NM_005192
CDKN3

cyclin-dependent kinase inhibitor 3

chr2_-_62115641 19.121 CCT4
chaperonin containing TCP1, subunit 4 (delta)
chr2_+_85804724 19.087 VAMP8
vesicle-associated membrane protein 8 (endobrevin)
chr12_+_57623355 19.036 NM_001166356
NM_005412
SHMT2

serine hydroxymethyltransferase 2 (mitochondrial)

chr2_-_225370687 18.936 CUL3
cullin 3
chr20_+_31407696 18.825 NM_012325
MAPRE1
microtubule-associated protein, RP/EB family, member 1
chr5_+_10250440 18.723 CCT5
chaperonin containing TCP1, subunit 5 (epsilon)
chr17_-_7578810 18.709 NM_001126115
NM_001126116
NM_001126117
TP53


tumor protein p53


chr9_+_127962850 18.598 NM_005833
RABEPK
Rab9 effector protein with kelch motifs
chr16_+_88003623 18.539 NM_001173543
BANP
BTG3 associated nuclear protein
chr2_-_85641153 18.410 CAPG
capping protein (actin filament), gelsolin-like
chr5_+_10250403 18.364 CCT5
chaperonin containing TCP1, subunit 5 (epsilon)
chr16_-_28437663 18.346 NM_001199142
EIF3C
eukaryotic translation initiation factor 3, subunit C
chr15_-_78591902 18.311 NM_025234
WDR61
WD repeat domain 61
chr3_+_183892699 18.305 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr19_+_41798147 18.264 HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr1_+_110543548 18.223 NM_001242674
AHCYL1
adenosylhomocysteinase-like 1
chr10_+_102123420 18.216


chr2_-_85637486 18.016 NM_001747
CAPG
capping protein (actin filament), gelsolin-like
chr2_+_231921562 17.922 NM_001191037
NM_002807
PSMD1

proteasome (prosome, macropain) 26S subunit, non-ATPase, 1

chr7_+_28725597 17.856 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr3_-_194188967 17.796 NM_024524
ATP13A3
ATPase type 13A3
chr11_+_17332454 17.677


chr18_+_29671817 17.590 NM_016271
RNF138
ring finger protein 138
chr13_-_46756295 17.498 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr2_+_231921625 17.432 PSMD1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr2_+_231921608 17.399 PSMD1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr2_-_85641128 17.157 CAPG
capping protein (actin filament), gelsolin-like
chr9_-_88715024 17.138 NM_177937
GOLM1
golgi membrane protein 1
chr7_-_99699426 16.990 NM_005916
MCM7
minichromosome maintenance complex component 7
chr1_-_150207025 16.901 NM_001136479
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr18_-_55289014 16.836 NARS
asparaginyl-tRNA synthetase
chr7_-_66057331 16.784 LOC493754
RAB guanine nucleotide exchange factor (GEF) 1 pseudogene
chr2_-_62115726 16.762 CCT4
chaperonin containing TCP1, subunit 4 (delta)
chr19_+_13134782 16.744 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr12_-_123706393 16.637 NM_022782
MPHOSPH9
M-phase phosphoprotein 9
chr9_+_127962809 16.616 NM_001174152
NM_001174153
RABEPK

Rab9 effector protein with kelch motifs

chr3_+_183892662 16.495 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr1_+_203830723 16.485 SNRPE
small nuclear ribonucleoprotein polypeptide E
chr5_+_10250370 16.351 CCT5
chaperonin containing TCP1, subunit 5 (epsilon)
chr3_+_183892647 16.327 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chrX_-_129272014 16.148 NM_001130846
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr7_-_87849341 16.114 SRI
sorcin
chr10_-_58121019 16.061 NM_001005413
NM_007057
NM_032997
ZWINT


ZW10 interactor


chr7_+_55433396 16.054 LANCL2
LanC lantibiotic synthetase component C-like 2 (bacterial)
chr3_-_52569021 15.994 NM_022908
NT5DC2
5'-nucleotidase domain containing 2
chr3_-_79817058 15.985 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr6_+_44187241 15.934 NM_001078174
NM_004955
SLC29A1

solute carrier family 29 (nucleoside transporters), member 1

chr11_-_16996559 15.915 RPL36A
ribosomal protein L36a
chr6_-_38670915 15.879 GLO1
glyoxalase I
chr14_-_55650348 15.875 DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr6_-_38670882 15.813 GLO1
glyoxalase I
chr15_+_89787184 15.807 NM_001113378
NM_018193
FANCI

Fanconi anemia, complementation group I

chr16_+_56817367 15.803 NM_001242796
NUP93
nucleoporin 93kDa
chr3_-_49066813 15.743 IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr1_+_203830732 15.693 NM_003094
SNRPE
small nuclear ribonucleoprotein polypeptide E
chr10_-_58121011 15.514 ZWINT
ZW10 interactor
chr22_-_42343079 15.483 NM_001002876
NM_024053
CENPM

centromere protein M

chr17_+_4699456 15.460 NM_002798
PSMB6
proteasome (prosome, macropain) subunit, beta type, 6
chr6_+_34725266 15.439 SNRPC
small nuclear ribonucleoprotein polypeptide C
chr12_+_16064105 15.372 NM_015954
DERA
deoxyribose-phosphate aldolase (putative)
chr2_+_171784947 15.369 NM_001201428
NM_015530
GORASP2

golgi reassembly stacking protein 2, 55kDa

chr10_-_98325100 15.328 TM9SF3
transmembrane 9 superfamily member 3
chr12_-_120638912 15.307 NM_001002
NM_053275
RPLP0

ribosomal protein, large, P0

chr1_-_45452266 15.161 NM_001166588
NM_020365
EIF2B3

eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa

chr5_+_10250410 15.114 CCT5
chaperonin containing TCP1, subunit 5 (epsilon)
chr2_+_170662044 14.973 SSB
Sjogren syndrome antigen B (autoantigen La)
chr9_-_35079751 14.863 NM_004629
FANCG
Fanconi anemia, complementation group G
chr7_+_94292737 14.803 PEG10
paternally expressed 10
chr1_+_203830763 14.759 SNRPE
small nuclear ribonucleoprotein polypeptide E
chr18_+_29671925 14.751 RNF138
ring finger protein 138
chr12_+_16064232 14.683 DERA
deoxyribose-phosphate aldolase (putative)
chr13_-_46756326 14.602 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr8_-_71581419 14.538 NM_016027
LACTB2
lactamase, beta 2
chr12_+_16064282 14.533 DERA
deoxyribose-phosphate aldolase (putative)
chr2_+_223725675 14.446 NM_004457
NM_203372
ACSL3

acyl-CoA synthetase long-chain family member 3

chr2_+_231921595 14.373 PSMD1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr6_+_119215240 14.341 NM_014034
ASF1A
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr9_-_130700762 14.339 NM_003863
DPM2
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
chr9_+_110047049 14.331 NM_001244713
RAD23B
RAD23 homolog B (S. cerevisiae)
chr3_-_49066858 14.327 NM_000884
IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr12_-_96429397 14.288 LTA4H
leukotriene A4 hydrolase
chr17_+_4699473 14.030 PSMB6
proteasome (prosome, macropain) subunit, beta type, 6
chr6_-_170862326 14.014 PSMB1
proteasome (prosome, macropain) subunit, beta type, 1
chr6_-_38670871 13.995 GLO1
glyoxalase I
chr18_+_3447607 13.921 NM_173207
TGIF1
TGFB-induced factor homeobox 1
chr1_-_154580481 13.848 ADAR
adenosine deaminase, RNA-specific
chr12_+_56915587 13.837 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr1_-_93646245 13.815 NM_001167830
NM_016040
TMED5

transmembrane emp24 protein transport domain containing 5

chr16_-_47005339 13.744 DNAJA2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr7_+_28475233 13.710 NM_004904
CREB5
cAMP responsive element binding protein 5
chr7_+_32996961 13.692 NM_007270
FKBP9
FK506 binding protein 9, 63 kDa
chr3_-_185655806 13.682 TRA2B
transformer 2 beta homolog (Drosophila)
chr7_+_94292816 13.670 PEG10
paternally expressed 10
chr8_-_71520433 13.647 TRAM1
translocation associated membrane protein 1
chr7_-_95064213 13.566 NM_000305
NM_001018161
PON2

paraoxonase 2

chr2_-_18770776 13.553 NM_001199103
NM_001199104
NM_001002006
NM_001199086
NM_001199087
NM_001199088
NM_033253
NT5C1B-RDH14

NT5C1B




NT5C1B-RDH14 readthrough

5'-nucleotidase, cytosolic IB




chr12_+_64803741 13.459 XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr10_-_27057776 13.338 ABI1
abl-interactor 1
chr3_+_183892569 13.335 NM_001025205
NM_004068
AP2M1

adaptor-related protein complex 2, mu 1 subunit

chr19_+_3198813 13.229 NCLN
nicalin
chr9_-_14086901 13.197 NFIB
nuclear factor I/B
chr6_-_24719286 13.068 NM_030939
C6orf62
chromosome 6 open reading frame 62
chr9_+_110046333 12.978 NM_001244724
RAD23B
RAD23 homolog B (S. cerevisiae)
chr12_+_32832128 12.912 NM_005690
NM_012062
NM_012063
DNM1L


dynamin 1-like


chr12_-_120638909 12.857 RPLP0
ribosomal protein, large, P0
chr5_+_162864571 12.761 NM_004060
NM_199246
CCNG1

cyclin G1

chr6_-_38670904 12.755 GLO1
glyoxalase I
chr17_+_26794838 12.747


chr22_-_41252646 12.719 ST13
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.23 1.15e-38 GO:0009987 cellular process
1.43 1.76e-36 GO:0044237 cellular metabolic process
1.37 2.30e-33 GO:0008152 metabolic process
1.39 1.52e-30 GO:0044238 primary metabolic process
1.70 5.80e-29 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.64 9.21e-29 GO:0034641 cellular nitrogen compound metabolic process
1.50 7.02e-28 GO:0044260 cellular macromolecule metabolic process
1.60 6.36e-27 GO:0006807 nitrogen compound metabolic process
1.44 2.53e-25 GO:0043170 macromolecule metabolic process
1.70 8.03e-22 GO:0090304 nucleic acid metabolic process
1.75 5.02e-20 GO:0010467 gene expression
1.74 6.34e-18 GO:0016070 RNA metabolic process
1.52 1.57e-15 GO:0071841 cellular component organization or biogenesis at cellular level
1.43 1.76e-14 GO:0071840 cellular component organization or biogenesis
1.54 1.81e-14 GO:0044249 cellular biosynthetic process
1.52 5.09e-14 GO:0009058 biosynthetic process
1.66 9.47e-14 GO:0009059 macromolecule biosynthetic process
1.66 1.49e-13 GO:0034645 cellular macromolecule biosynthetic process
1.50 2.16e-13 GO:0071842 cellular component organization at cellular level
2.17 1.24e-12 GO:0000278 mitotic cell cycle
1.41 1.36e-12 GO:0016043 cellular component organization
1.83 2.57e-12 GO:0007049 cell cycle
1.95 3.52e-12 GO:0022402 cell cycle process
2.04 3.77e-12 GO:0022403 cell cycle phase
1.62 1.17e-11 GO:0006996 organelle organization
2.52 2.60e-10 GO:0051329 interphase of mitotic cell cycle
2.47 6.71e-10 GO:0051325 interphase
1.44 2.28e-09 GO:0044267 cellular protein metabolic process
1.94 4.93e-09 GO:0006396 RNA processing
2.70 7.70e-09 GO:0000075 cell cycle checkpoint
1.94 9.97e-09 GO:0051726 regulation of cell cycle
2.64 1.25e-08 GO:0071156 regulation of cell cycle arrest
1.43 1.38e-08 GO:0048519 negative regulation of biological process
2.01 1.63e-08 GO:0016071 mRNA metabolic process
1.94 1.79e-08 GO:0051276 chromosome organization
1.72 3.00e-08 GO:0032774 RNA biosynthetic process
2.03 4.96e-08 GO:0034621 cellular macromolecular complex subunit organization
1.36 7.58e-08 GO:0019538 protein metabolic process
2.68 9.53e-08 GO:0022613 ribonucleoprotein complex biogenesis
2.22 1.23e-07 GO:0010564 regulation of cell cycle process
2.97 1.54e-07 GO:0000082 G1/S transition of mitotic cell cycle
2.14 1.77e-07 GO:0006397 mRNA processing
2.59 2.29e-07 GO:0071843 cellular component biogenesis at cellular level
1.42 6.00e-07 GO:0048523 negative regulation of cellular process
2.21 2.25e-06 GO:0008380 RNA splicing
2.19 3.54e-06 GO:0006412 translation
1.69 3.70e-06 GO:0043933 macromolecular complex subunit organization
2.20 3.80e-06 GO:0000087 M phase of mitotic cell cycle
2.16 1.15e-05 GO:0048285 organelle fission
1.94 1.52e-05 GO:0000279 M phase
2.21 1.93e-05 GO:0007346 regulation of mitotic cell cycle
2.16 2.09e-05 GO:0000280 nuclear division
2.16 2.09e-05 GO:0007067 mitosis
2.46 2.73e-05 GO:0022411 cellular component disassembly
2.46 2.73e-05 GO:0071845 cellular component disassembly at cellular level
1.15 2.84e-05 GO:0065007 biological regulation
1.16 3.05e-05 GO:0050789 regulation of biological process
2.39 3.16e-05 GO:0000375 RNA splicing, via transesterification reactions
2.40 3.86e-05 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.40 3.86e-05 GO:0000398 nuclear mRNA splicing, via spliceosome
1.52 4.72e-05 GO:0044085 cellular component biogenesis
2.63 7.90e-05 GO:0031016 pancreas development
1.32 9.18e-05 GO:0048518 positive regulation of biological process
2.79 9.36e-05 GO:0031018 endocrine pancreas development
1.91 9.62e-05 GO:0016032 viral reproduction
2.85 1.53e-04 GO:0032984 macromolecular complex disassembly
2.85 1.53e-04 GO:0034623 cellular macromolecular complex disassembly
1.59 1.80e-04 GO:0006351 transcription, DNA-dependent
3.15 1.87e-04 GO:0022618 ribonucleoprotein complex assembly
1.61 1.93e-04 GO:0033554 cellular response to stress
2.82 1.95e-04 GO:0000084 S phase of mitotic cell cycle
1.32 2.50e-04 GO:0048522 positive regulation of cellular process
2.77 3.09e-04 GO:0051320 S phase
3.08 3.26e-04 GO:0000236 mitotic prometaphase
1.54 3.99e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.81 4.01e-04 GO:0006325 chromatin organization
2.61 5.38e-04 GO:0007093 mitotic cell cycle checkpoint
1.15 6.09e-04 GO:0050794 regulation of cellular process
1.75 6.79e-04 GO:0006974 response to DNA damage stimulus
2.97 7.21e-04 GO:0071826 ribonucleoprotein complex subunit organization
1.89 1.50e-03 GO:0051301 cell division
2.79 1.70e-03 GO:0043241 protein complex disassembly
2.79 1.70e-03 GO:0043624 cellular protein complex disassembly
1.83 1.75e-03 GO:0006091 generation of precursor metabolites and energy
1.87 1.86e-03 GO:0016568 chromatin modification
2.61 2.04e-03 GO:0031570 DNA integrity checkpoint
1.87 2.07e-03 GO:0034622 cellular macromolecular complex assembly
2.85 2.79e-03 GO:0006415 translational termination
2.24 3.39e-03 GO:0035270 endocrine system development
2.50 3.77e-03 GO:0045333 cellular respiration
1.65 3.87e-03 GO:0006259 DNA metabolic process
1.86 4.10e-03 GO:0018193 peptidyl-amino acid modification
2.30 4.70e-03 GO:0022415 viral reproductive process
1.42 4.86e-03 GO:0051641 cellular localization
2.84 5.10e-03 GO:0019080 viral genome expression
2.84 5.10e-03 GO:0019083 viral transcription
1.44 5.24e-03 GO:0044248 cellular catabolic process
2.59 5.34e-03 GO:0000077 DNA damage checkpoint
1.43 5.93e-03 GO:0031325 positive regulation of cellular metabolic process
1.44 7.03e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.67 7.40e-03 GO:0044265 cellular macromolecule catabolic process
1.28 8.19e-03 GO:0006950 response to stress
1.56 1.02e-02 GO:0065003 macromolecular complex assembly
7.64 1.08e-02 GO:0040001 establishment of mitotic spindle localization
1.38 1.15e-02 GO:0009056 catabolic process
1.40 1.20e-02 GO:0009893 positive regulation of metabolic process
1.48 1.27e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.86 1.63e-02 GO:0048610 cellular process involved in reproduction
1.22 1.64e-02 GO:0060255 regulation of macromolecule metabolic process
2.77 2.15e-02 GO:0000216 M/G1 transition of mitotic cell cycle
2.77 2.15e-02 GO:0031575 mitotic cell cycle G1/S transition checkpoint
2.77 2.15e-02 GO:0071779 G1/S transition checkpoint
1.45 2.15e-02 GO:0009892 negative regulation of metabolic process
2.31 2.23e-02 GO:0019058 viral infectious cycle
1.32 2.38e-02 GO:0044281 small molecule metabolic process
1.58 2.45e-02 GO:0009057 macromolecule catabolic process
1.59 2.52e-02 GO:0071822 protein complex subunit organization
1.42 2.67e-02 GO:0008104 protein localization
2.89 2.80e-02 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
2.35 2.86e-02 GO:0042254 ribosome biogenesis
1.43 2.90e-02 GO:0022607 cellular component assembly
1.60 2.94e-02 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
2.51 3.69e-02 GO:0006414 translational elongation
1.42 4.01e-02 GO:0010941 regulation of cell death
1.66 4.25e-02 GO:0060548 negative regulation of cell death
2.43 4.42e-02 GO:0090068 positive regulation of cell cycle process
1.49 4.75e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.40 4.79e-02 GO:0051649 establishment of localization in cell

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.23 5.23e-43 GO:0044424 intracellular part
1.21 2.96e-38 GO:0005622 intracellular
1.28 1.30e-31 GO:0043227 membrane-bounded organelle
1.28 1.39e-31 GO:0043231 intracellular membrane-bounded organelle
1.25 1.39e-30 GO:0043229 intracellular organelle
1.24 1.97e-30 GO:0043226 organelle
1.29 9.55e-30 GO:0005737 cytoplasm
1.41 4.06e-29 GO:0044446 intracellular organelle part
1.41 9.22e-29 GO:0044422 organelle part
1.76 2.88e-27 GO:0044428 nuclear part
1.69 6.89e-25 GO:0031974 membrane-enclosed lumen
1.70 9.98e-25 GO:0043233 organelle lumen
1.69 2.86e-23 GO:0070013 intracellular organelle lumen
1.77 1.37e-22 GO:0031981 nuclear lumen
1.33 4.32e-21 GO:0044444 cytoplasmic part
1.35 2.25e-20 GO:0005634 nucleus
1.45 7.70e-18 GO:0032991 macromolecular complex
1.82 1.69e-17 GO:0005654 nucleoplasm
1.61 1.36e-16 GO:0005829 cytosol
2.09 7.94e-11 GO:0030529 ribonucleoprotein complex
1.40 3.02e-10 GO:0043228 non-membrane-bounded organelle
1.40 3.02e-10 GO:0043232 intracellular non-membrane-bounded organelle
1.59 3.28e-09 GO:0005739 mitochondrion
1.06 5.16e-09 GO:0044464 cell part
1.06 5.42e-09 GO:0005623 cell
1.95 6.92e-09 GO:0005694 chromosome
1.36 7.96e-09 GO:0043234 protein complex
1.74 3.95e-07 GO:0044451 nucleoplasm part
1.90 1.82e-06 GO:0044427 chromosomal part
1.71 2.39e-06 GO:0031967 organelle envelope
1.69 3.54e-06 GO:0031975 envelope
1.32 3.44e-04 GO:0031090 organelle membrane
1.71 3.83e-04 GO:0005730 nucleolus
2.05 4.02e-04 GO:0005635 nuclear envelope
2.16 1.02e-03 GO:0005840 ribosome
2.35 1.65e-03 GO:0005681 spliceosomal complex
1.54 3.08e-03 GO:0044429 mitochondrial part
1.92 6.39e-03 GO:0000785 chromatin
2.03 1.05e-02 GO:0005819 spindle
1.63 1.24e-02 GO:0031966 mitochondrial membrane
3.80 1.30e-02 GO:0030532 small nuclear ribonucleoprotein complex
1.92 1.60e-02 GO:0000228 nuclear chromosome
1.88 2.00e-02 GO:0016604 nuclear body
2.21 2.89e-02 GO:0044455 mitochondrial membrane part
2.07 4.01e-02 GO:0000775 chromosome, centromeric region

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.38 9.44e-40 GO:0005515 protein binding
1.17 5.86e-25 GO:0005488 binding
1.80 8.15e-10 GO:0003723 RNA binding
1.28 9.65e-06 GO:0003676 nucleic acid binding
1.33 3.75e-05 GO:0000166 nucleotide binding
1.86 1.98e-04 GO:0003712 transcription cofactor activity
1.86 2.20e-04 GO:0000988 protein binding transcription factor activity
1.86 2.20e-04 GO:0000989 transcription factor binding transcription factor activity
2.34 1.00e-03 GO:0003735 structural constituent of ribosome
1.17 1.67e-03 GO:0003824 catalytic activity
1.54 1.74e-03 GO:0019899 enzyme binding
2.24 5.64e-03 GO:0003714 transcription corepressor activity
3.34 6.77e-03 GO:0051287 NAD binding
1.72 1.66e-02 GO:0016887 ATPase activity
2.55 3.37e-02 GO:0016651 oxidoreductase activity, acting on NADH or NADPH
1.45 3.60e-02 GO:0017111 nucleoside-triphosphatase activity
1.44 4.13e-02 GO:0016462 pyrophosphatase activity
1.44 4.88e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides