Motif ID: CACAGUG

Z-value: 1.402


Mature miRNA associated with seed CACAGUG:

NamemiRBase Accession
hsa-miR-128 MIMAT0000424



Activity profile for motif CACAGUG.

activity profile for motif CACAGUG


Sorted Z-values histogram for motif CACAGUG

Sorted Z-values for motif CACAGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of CACAGUG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_92790151 54.876 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr14_+_92789536 49.460 NM_153647
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr14_+_92788924 40.094 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chrX_+_64708614 36.150 NM_001010888
ZC3H12B
zinc finger CCCH-type containing 12B
chr20_+_10199455 31.110 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr17_+_18218569 30.069 NM_144775
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr19_+_32896515 27.794 NM_001172774
DPY19L3
dpy-19-like 3 (C. elegans)
chr2_+_242641310 27.048 NM_032329
ING5
inhibitor of growth family, member 5
chr12_+_121078421 25.525 NM_001033677
CABP1
calcium binding protein 1
chr18_+_55102777 24.813 NM_004852
ONECUT2
one cut homeobox 2
chr1_-_85725315 23.884 NM_198077
C1orf52
chromosome 1 open reading frame 52
chr11_-_18655962 23.224 NM_194285
SPTY2D1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr19_+_7968764 22.461 NM_145185
MAP2K7
mitogen-activated protein kinase kinase 7
chr6_+_122793061 22.336 NM_181794
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr2_-_206950895 22.173 NM_017759
INO80D
INO80 complex subunit D
chr16_-_4292052 20.869 NM_001098814
SRL
sarcalumenin
chr12_+_121088370 20.636 NM_004276
NM_031205
CABP1

calcium binding protein 1

chr12_-_123451031 20.609 NM_001243013
NM_001243014
NM_019624
NM_019625
NM_203444
ABCB9




ATP-binding cassette, sub-family B (MDR/TAP), member 9




chr6_+_41606193 20.585 NM_005586
MDFI
MyoD family inhibitor
chr13_-_37494370 20.201 NM_001127217
NM_005905
SMAD9

SMAD family member 9

chr11_+_12695851 20.004 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr7_-_103629962 19.768 NM_005045
NM_173054
RELN

reelin

chr12_+_79257772 19.611 NM_001135805
SYT1
synaptotagmin I
chr5_-_115910406 19.291 NM_020796
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr2_+_31456879 18.532 NM_014600
EHD3
EH-domain containing 3
chr16_-_70719854 18.445 NM_138383
MTSS1L
metastasis suppressor 1-like
chr12_-_42538432 18.154 NM_001099650
NM_173601
GXYLT1

glucoside xylosyltransferase 1

chr7_-_37393271 18.073 NM_001206482
ELMO1
engulfment and cell motility 1
chr1_+_180601121 18.025 NM_001135669
NM_004736
XPR1

xenotropic and polytropic retrovirus receptor 1

chr6_+_11538486 17.953 NM_001100829
TMEM170B
transmembrane protein 170B
chrX_-_40594774 17.471 NM_004229
MED14
mediator complex subunit 14
chr8_-_41754244 17.348 NM_001142446
ANK1
ankyrin 1, erythrocytic
chrX_-_54384436 17.315 NM_001002838
NM_020922
WNK3

WNK lysine deficient protein kinase 3

chr10_-_90750955 17.171 NM_001141945
ACTA2
actin, alpha 2, smooth muscle, aorta
chr5_-_132299263 17.127 NM_014423
AFF4
AF4/FMR2 family, member 4
chr7_+_138916230 16.996 NM_173569
UBN2
ubinuclein 2
chr14_+_99947732 16.664 NM_001099402
CCNK
cyclin K
chr12_+_79439432 16.494 NM_001135806
SYT1
synaptotagmin I
chr16_+_66914380 16.445 NM_020786
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr3_+_11034419 16.350 NM_003042
SLC6A1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr16_+_2587951 16.255 NM_002613
NM_031268
PDPK1

3-phosphoinositide dependent protein kinase-1

chr12_-_124457099 16.116 NM_025140
CCDC92
coiled-coil domain containing 92
chr16_+_1756161 15.901 NM_001040439
NM_015133
MAPK8IP3

mitogen-activated protein kinase 8 interacting protein 3

chr6_-_119399759 15.531 NM_024581
FAM184A
family with sequence similarity 184, member A
chr7_-_28998028 15.477 NM_014817
TRIL
TLR4 interactor with leucine-rich repeats
chr5_-_95297597 15.467 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr2_-_71454200 15.215 NM_020459
PAIP2B
poly(A) binding protein interacting protein 2B
chr12_+_79258448 15.093 NM_005639
SYT1
synaptotagmin I
chr6_-_46293628 15.088 NM_005822
RCAN2
regulator of calcineurin 2
chr20_+_24449834 14.842 NM_024893
SYNDIG1
synapse differentiation inducing 1
chr1_-_92371558 14.751 NM_001195684
TGFBR3
transforming growth factor, beta receptor III
chr9_-_26947435 14.726 NM_001031689
PLAA
phospholipase A2-activating protein
chr5_-_93447237 14.686 NM_001163417
NM_001163418
NM_032042
FAM172A


family with sequence similarity 172, member A


chr10_-_21463019 14.470 NM_001173484
NM_213569
NEBL

nebulette

chr2_-_27718098 14.463 NM_022823
FNDC4
fibronectin type III domain containing 4
chr7_-_27183225 14.448 NM_019102
HOXA5
homeobox A5
chr13_+_113623496 14.434 NM_001112732
MCF2L
MCF.2 cell line derived transforming sequence-like
chr5_-_111754738 14.381 NM_022140
EPB41L4A
erythrocyte membrane protein band 4.1 like 4A
chr14_+_35515347 14.353 NM_173607
FAM177A1
family with sequence similarity 177, member A1
chr15_-_77712436 14.171 NM_024776
PEAK1
NKF3 kinase family member
chr9_+_34958171 14.158 NM_015297
KIAA1045
KIAA1045
chr8_-_10587942 14.132 NM_031439
SOX7
SRY (sex determining region Y)-box 7
chr7_-_139876718 13.937 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr19_-_13617037 13.932 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr16_-_4588379 13.905 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr13_-_41240607 13.817 NM_002015
FOXO1
forkhead box O1
chr3_-_170303774 13.812 NM_020949
SLC7A14
solute carrier family 7 (orphan transporter), member 14
chr6_+_126240369 13.803 NM_001199622
NCOA7
nuclear receptor coactivator 7
chr3_+_23987514 13.705 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr17_-_37557851 13.660 NM_001184906
NM_032875
FBXL20

F-box and leucine-rich repeat protein 20

chr6_+_126111782 13.612 NM_001122842
NM_001199621
NM_181782
NCOA7


nuclear receptor coactivator 7


chr1_+_38261079 13.573 NM_152496
MANEAL
mannosidase, endo-alpha-like
chr11_-_102962903 13.440 NM_032299
DCUN1D5
DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
chr1_-_57045235 13.257 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr11_-_117186918 13.209 NM_012104
NM_138971
NM_138972
NM_138973
BACE1



beta-site APP-cleaving enzyme 1



chrX_+_70315637 13.183 NM_001170931
NM_005938
FOXO4

forkhead box O4

chr2_-_201936389 12.886 NM_173822
FAM126B
family with sequence similarity 126, member B
chr1_+_54519259 12.820 NM_153035
TCEANC2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr6_+_126102278 12.742 NM_001199619
NM_001199620
NCOA7

nuclear receptor coactivator 7

chr18_+_43753986 12.737 NM_001008239
NM_145055
C18orf25

chromosome 18 open reading frame 25

chr10_-_91403630 12.572 NM_138316
NM_148978
PANK1

pantothenate kinase 1

chr1_-_202679415 12.554 NM_177402
SYT2
synaptotagmin II
chr8_-_127570710 12.472 NM_174911
FAM84B
family with sequence similarity 84, member B
chr4_+_85504056 12.422 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr17_-_63052884 12.396 NM_006572
GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr7_-_37488554 12.340 NM_014800
ELMO1
engulfment and cell motility 1
chr20_-_48532067 12.306 NM_006038
SPATA2
spermatogenesis associated 2
chr16_-_4588738 12.182 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr6_-_149806116 12.170 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr10_+_104503724 12.125 NM_001083913
C10orf26
chromosome 10 open reading frame 26
chr16_-_402617 12.086 NM_003502
NM_181050
AXIN1

axin 1

chr17_+_47865980 12.070 NM_001199155
NM_001199156
NM_001199157
NM_001199158
NM_007067
KAT7




K(lysine) acetyltransferase 7




chr10_+_18429605 11.913 NM_201593
NM_201596
NM_201597
NM_001167945
NM_201571
NM_201572
CACNB2





calcium channel, voltage-dependent, beta 2 subunit





chr1_+_11866206 11.874 NM_001286
NM_021735
NM_021736
NM_021737
CLCN6



chloride channel 6



chr6_-_41747586 11.863 NM_006653
FRS3
fibroblast growth factor receptor substrate 3
chr3_-_13114547 11.857 NM_001134382
IQSEC1
IQ motif and Sec7 domain 1
chr4_-_153456152 11.825 NM_033632
FBXW7
F-box and WD repeat domain containing 7
chr1_+_38259458 11.794 NM_001031740
NM_001113482
MANEAL

mannosidase, endo-alpha-like

chr20_+_48599511 11.762 NM_005985
SNAI1
snail homolog 1 (Drosophila)
chr15_+_29213839 11.687 NM_001130414
NM_005503
APBA2

amyloid beta (A4) precursor protein-binding, family A, member 2

chr19_-_344778 11.662 NM_017550
MIER2
mesoderm induction early response 1, family member 2
chr15_-_73661604 11.655 NM_005477
HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr7_+_45067232 11.610 NM_001029835
CCM2
cerebral cavernous malformation 2
chr4_-_7941092 11.604 NM_001134647
NM_198595
AFAP1

actin filament associated protein 1

chr17_+_56833231 11.583 NM_014906
PPM1E
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr1_-_92351613 11.545 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr13_-_80915041 11.508 NM_005842
SPRY2
sprouty homolog 2 (Drosophila)
chr2_+_43864433 11.470 NM_172069
PLEKHH2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr11_+_14665268 11.442 NM_000922
PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr14_-_53620032 11.313 NM_001160147
NM_001160148
NM_030637
DDHD1


DDHD domain containing 1


chr3_-_129612371 11.238 NM_001128224
TMCC1
transmembrane and coiled-coil domain family 1
chr1_-_202612580 11.141 NM_001136504
SYT2
synaptotagmin II
chr17_+_47572592 11.050 NM_002507
NGFR
nerve growth factor receptor
chr19_+_18794391 10.945 NM_001098482
NM_015321
CRTC1

CREB regulated transcription coactivator 1

chr22_-_28197469 10.870 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr8_-_41166931 10.827 NM_003012
SFRP1
secreted frizzled-related protein 1
chr4_+_55095263 10.549 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr3_+_183993798 10.534 NM_001037324
NM_001100120
NM_001100121
ECE2


endothelin converting enzyme 2


chr5_-_64920149 10.319 NM_001656
NM_033227
NM_033228
TRIM23


tripartite motif containing 23


chr7_-_37488894 10.318 NM_001206480
ELMO1
engulfment and cell motility 1
chr19_+_38397841 10.230 NM_015073
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr19_+_45971249 10.085 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr4_-_153303663 10.074 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr7_-_37024664 10.044 NM_001039459
ELMO1
engulfment and cell motility 1
chr14_+_35514112 10.028 NM_001079519
FAM177A1
family with sequence similarity 177, member A1
chr8_-_22550708 9.983 NM_004430
EGR3
early growth response 3
chr6_-_33267128 9.813 NM_001243738
NM_004761
RGL2

ral guanine nucleotide dissociation stimulator-like 2

chr4_+_144257982 9.741 NM_002039
NM_207123
GAB1

GRB2-associated binding protein 1

chr16_-_30107492 9.529 NM_031477
NM_001145524
YPEL3

yippee-like 3 (Drosophila)

chr8_+_1922030 9.399 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr3_-_128206704 9.297 NM_001145662
GATA2
GATA binding protein 2
chr1_+_27561006 9.289 NM_015023
WDTC1
WD and tetratricopeptide repeats 1
chr1_-_184006828 9.249 NM_015101
GLT25D2
glycosyltransferase 25 domain containing 2
chr1_+_221052735 9.217 NM_021958
HLX
H2.0-like homeobox
chr12_+_53773924 9.062 NM_001251825
NM_138473
SP1

Sp1 transcription factor

chr1_-_21616888 9.049 NM_001397
ECE1
endothelin converting enzyme 1
chr20_+_34742656 9.034 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr5_+_65017993 8.929 NM_020726
NLN
neurolysin (metallopeptidase M3 family)
chr6_-_29595934 8.907 NM_021903
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr6_-_88875766 8.818 NM_001160226
NM_001160258
NM_001160259
NM_016083
CNR1



cannabinoid receptor 1 (brain)



chr11_-_45687135 8.773 NM_003654
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr1_-_184724021 8.752 NM_025191
EDEM3
ER degradation enhancer, mannosidase alpha-like 3
chr17_+_25621105 8.746 NM_015626
NM_134265
WSB1

WD repeat and SOCS box containing 1

chr1_-_149889362 8.733 NM_014849
SV2A
synaptic vesicle glycoprotein 2A
chr16_-_68482373 8.726 NM_018667
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr3_-_129599220 8.713 NM_001017395
TMCC1
transmembrane and coiled-coil domain family 1
chr22_-_39240016 8.700 NM_014293
NPTXR
neuronal pentraxin receptor
chr17_+_29421941 8.584 NM_000267
NM_001042492
NM_001128147
NF1


neurofibromin 1


chrX_-_67653169 8.546 NM_002547
OPHN1
oligophrenin 1
chr16_-_48644087 8.508 NM_153029
N4BP1
NEDD4 binding protein 1
chr9_-_110252045 8.489 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr1_+_203274646 8.478 NM_006763
BTG2
BTG family, member 2
chr17_+_42385780 8.423 NM_001144825
NM_001144826
NM_006695
RUNDC3A


RUN domain containing 3A


chr10_-_81205091 8.355 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr2_-_100721792 8.296 NM_001025108
AFF3
AF4/FMR2 family, member 3
chr1_-_8483701 8.275 NM_001042682
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr9_+_112403067 8.273 NM_001037293
PALM2
paralemmin 2
chr7_+_148959219 8.234 NM_001195220
ZNF783
zinc finger family member 783
chr1_-_154474524 8.230 NM_001010846
SHE
Src homology 2 domain containing E
chr12_+_103981050 8.190 NM_017564
STAB2
stabilin 2
chr2_-_100758970 8.165 NM_002285
AFF3
AF4/FMR2 family, member 3
chr3_-_155421996 8.151 NM_014996
PLCH1
phospholipase C, eta 1
chr17_-_78450247 8.128 NM_002522
NPTX1
neuronal pentraxin I
chr4_+_113739203 7.947 NM_001127493
ANK2
ankyrin 2, neuronal
chr19_+_15218141 7.941 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr9_-_99382073 7.878 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr17_+_1959512 7.869 NM_001098202
HIC1
hypermethylated in cancer 1
chrX_+_16804531 7.860 NM_001168683
NM_018360
TXLNG

taxilin gamma

chr12_+_55413728 7.846 NM_021191
NEUROD4
neurogenic differentiation 4
chr20_+_20348744 7.844 NM_002196
INSM1
insulinoma-associated 1
chr9_-_100395961 7.836 NM_139246
TSTD2
thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
chr1_-_33815498 7.834 NM_004427
PHC2
polyhomeotic homolog 2 (Drosophila)
chr3_+_36421944 7.817 NM_003149
STAC
SH3 and cysteine rich domain
chr5_-_160279045 7.804 NM_025153
ATP10B
ATPase, class V, type 10B
chr14_-_92414004 7.789 NM_006329
FBLN5
fibulin 5
chr9_-_36400817 7.783 NM_194328
NM_194332
RNF38

ring finger protein 38

chr10_+_18549583 7.773 NM_000724
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr8_-_41655139 7.748 NM_000037
NM_020475
NM_020476
NM_020477
ANK1



ankyrin 1, erythrocytic



chr10_-_90712510 7.743 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr3_+_183967414 7.724 NM_014693
NM_032331
ECE2

endothelin converting enzyme 2

chr11_-_123525300 7.696 NM_001040151
NM_018400
SCN3B

sodium channel, voltage-gated, type III, beta

chr12_+_53774422 7.678 NM_003109
SP1
Sp1 transcription factor
chr16_+_66878281 7.658 NM_005182
CA7
carbonic anhydrase VII
chr6_-_88854989 7.652 NM_033181
CNR1
cannabinoid receptor 1 (brain)
chr16_+_66878840 7.643 NM_001014435
CA7
carbonic anhydrase VII
chr2_-_109605668 7.586 NM_022336
EDAR
ectodysplasin A receptor
chr14_-_27066959 7.568 NM_002515
NM_006489
NM_006491
NOVA1


neuro-oncological ventral antigen 1


chr1_+_204913353 7.552 NM_001160331
NFASC
neurofascin
chrX_+_122318095 7.542 NM_000828
NM_007325
GRIA3

glutamate receptor, ionotrophic, AMPA 3

chr11_-_74109417 7.533 NM_173582
PGM2L1
phosphoglucomutase 2-like 1
chr17_+_45973515 7.500 NM_003110
SP2
Sp2 transcription factor
chr4_+_56815036 7.490 NM_025009
CEP135
centrosomal protein 135kDa
chr3_-_129325175 7.482 NM_015103
PLXND1
plexin D1
chr9_+_101867401 7.438 NM_001130916
NM_004612
TGFBR1

transforming growth factor, beta receptor 1

chr9_-_23821842 7.433 NM_001171195
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr9_-_93405066 7.429 NM_017594
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr16_+_66400524 7.407 NM_001795
CDH5
cadherin 5, type 2 (vascular endothelium)
chr2_+_192542860 7.386 NM_001031716
OBFC2A
oligonucleotide/oligosaccharide-binding fold containing 2A
chr6_-_13486382 7.364 NM_001242628
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr8_-_22549901 7.355 NM_001199880
EGR3
early growth response 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.01 3.01e-19 GO:0007275 multicellular organismal development
1.92 6.88e-18 GO:0032502 developmental process
1.94 1.26e-14 GO:0048856 anatomical structure development
2.01 1.40e-14 GO:0048731 system development
1.64 4.07e-14 GO:0032501 multicellular organismal process
2.50 6.13e-14 GO:0009653 anatomical structure morphogenesis
1.50 7.48e-14 GO:0050794 regulation of cellular process
2.45 8.66e-13 GO:0007399 nervous system development
1.45 4.50e-12 GO:0050789 regulation of biological process
1.77 5.06e-12 GO:0023052 signaling
2.11 9.45e-12 GO:0048869 cellular developmental process
2.11 2.30e-11 GO:0030154 cell differentiation
1.41 2.43e-11 GO:0065007 biological regulation
3.15 9.44e-11 GO:0010628 positive regulation of gene expression
2.90 9.46e-10 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.71 1.25e-09 GO:0031323 regulation of cellular metabolic process
1.86 1.57e-09 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.91 1.80e-09 GO:0048522 positive regulation of cellular process
3.48 2.40e-09 GO:0072358 cardiovascular system development
3.48 2.40e-09 GO:0072359 circulatory system development
3.10 2.57e-09 GO:0045893 positive regulation of transcription, DNA-dependent
2.82 3.29e-09 GO:0051173 positive regulation of nitrogen compound metabolic process
1.84 3.97e-09 GO:0048518 positive regulation of biological process
1.64 7.09e-09 GO:0019222 regulation of metabolic process
2.83 7.34e-09 GO:2000026 regulation of multicellular organismal development
1.69 7.65e-09 GO:0080090 regulation of primary metabolic process
2.04 8.08e-09 GO:0048513 organ development
2.95 1.02e-08 GO:0051254 positive regulation of RNA metabolic process
1.81 1.34e-08 GO:0051171 regulation of nitrogen compound metabolic process
2.38 1.68e-08 GO:0010604 positive regulation of macromolecule metabolic process
2.80 1.69e-08 GO:0010557 positive regulation of macromolecule biosynthetic process
2.59 1.87e-08 GO:0022008 neurogenesis
2.59 1.87e-08 GO:0050793 regulation of developmental process
2.34 2.30e-08 GO:0031325 positive regulation of cellular metabolic process
1.80 3.68e-08 GO:0031326 regulation of cellular biosynthetic process
3.31 3.76e-08 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.61 4.56e-08 GO:0048699 generation of neurons
2.28 4.71e-08 GO:0009893 positive regulation of metabolic process
1.78 7.80e-08 GO:0009889 regulation of biosynthetic process
1.67 9.00e-08 GO:0007165 signal transduction
2.46 1.15e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.58 1.62e-07 GO:0031328 positive regulation of cellular biosynthetic process
2.79 2.02e-07 GO:0045595 regulation of cell differentiation
2.48 2.26e-07 GO:0048468 cell development
2.54 3.10e-07 GO:0009891 positive regulation of biosynthetic process
1.85 5.62e-07 GO:0006355 regulation of transcription, DNA-dependent
1.80 5.65e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.82 1.08e-06 GO:0051252 regulation of RNA metabolic process
2.83 1.18e-06 GO:0009887 organ morphogenesis
2.68 1.22e-06 GO:0009790 embryo development
3.37 2.39e-06 GO:0048598 embryonic morphogenesis
1.75 2.69e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.73 3.69e-06 GO:0010468 regulation of gene expression
2.61 4.30e-06 GO:0030182 neuron differentiation
1.61 4.76e-06 GO:0060255 regulation of macromolecule metabolic process
3.84 4.85e-06 GO:0045596 negative regulation of cell differentiation
3.42 5.54e-06 GO:0007389 pattern specification process
2.29 6.52e-06 GO:0032879 regulation of localization
2.08 1.11e-05 GO:0051239 regulation of multicellular organismal process
1.51 1.73e-05 GO:0051716 cellular response to stimulus
1.91 2.76e-05 GO:0023051 regulation of signaling
2.69 3.19e-05 GO:0048666 neuron development
2.29 4.57e-05 GO:0006351 transcription, DNA-dependent
3.50 6.68e-05 GO:0035295 tube development
2.29 6.90e-05 GO:0009888 tissue development
2.59 9.01e-05 GO:0000902 cell morphogenesis
3.25 9.58e-05 GO:0051093 negative regulation of developmental process
3.38 1.34e-04 GO:0001944 vasculature development
2.69 2.44e-04 GO:0000904 cell morphogenesis involved in differentiation
3.59 2.53e-04 GO:0007507 heart development
1.76 3.52e-04 GO:0048583 regulation of response to stimulus
2.45 3.65e-04 GO:0032989 cellular component morphogenesis
2.97 3.86e-04 GO:0043009 chordate embryonic development
2.73 4.04e-04 GO:0048646 anatomical structure formation involved in morphogenesis
1.89 4.39e-04 GO:0009966 regulation of signal transduction
2.94 4.95e-04 GO:0009792 embryo development ending in birth or egg hatching
3.24 5.44e-04 GO:0051270 regulation of cellular component movement
2.75 5.47e-04 GO:0048812 neuron projection morphogenesis
2.64 5.63e-04 GO:0031175 neuron projection development
3.05 5.93e-04 GO:0045597 positive regulation of cell differentiation
2.73 6.45e-04 GO:0051094 positive regulation of developmental process
3.08 8.29e-04 GO:0060284 regulation of cell development
2.09 8.39e-04 GO:0042127 regulation of cell proliferation
2.60 8.49e-04 GO:0048858 cell projection morphogenesis
2.58 1.04e-03 GO:0032990 cell part morphogenesis
2.71 1.15e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
2.07 1.19e-03 GO:0032774 RNA biosynthetic process
2.36 1.41e-03 GO:0030030 cell projection organization
1.83 1.49e-03 GO:0065009 regulation of molecular function
2.72 1.64e-03 GO:0007409 axonogenesis
3.22 1.81e-03 GO:0001568 blood vessel development
2.95 1.90e-03 GO:0007411 axon guidance
2.81 1.92e-03 GO:0060429 epithelium development
2.49 3.10e-03 GO:0007417 central nervous system development
3.01 3.53e-03 GO:0048729 tissue morphogenesis
3.17 4.06e-03 GO:0030334 regulation of cell migration
3.13 4.98e-03 GO:2000145 regulation of cell motility
3.60 5.60e-03 GO:0035239 tube morphogenesis
2.99 6.39e-03 GO:0040012 regulation of locomotion
2.81 7.38e-03 GO:0009894 regulation of catabolic process
1.61 8.43e-03 GO:0048523 negative regulation of cellular process
3.46 9.81e-03 GO:0048732 gland development
1.57 1.15e-02 GO:0048519 negative regulation of biological process
3.14 1.35e-02 GO:0003002 regionalization
1.66 1.35e-02 GO:0007166 cell surface receptor linked signaling pathway
2.32 1.42e-02 GO:0051253 negative regulation of RNA metabolic process
1.90 1.47e-02 GO:0010646 regulation of cell communication
1.77 1.60e-02 GO:0035556 intracellular signal transduction
2.15 1.69e-02 GO:0031327 negative regulation of cellular biosynthetic process
2.81 1.77e-02 GO:0022603 regulation of anatomical structure morphogenesis
2.21 2.31e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.30 2.41e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.15 2.54e-02 GO:0009987 cellular process
2.11 2.71e-02 GO:0009890 negative regulation of biosynthetic process
2.08 2.71e-02 GO:0051049 regulation of transport
2.18 3.02e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
2.79 3.17e-02 GO:0006366 transcription from RNA polymerase II promoter
1.28 3.26e-02 GO:0050896 response to stimulus
2.33 3.39e-02 GO:0019226 transmission of nerve impulse
2.33 3.39e-02 GO:0035637 multicellular organismal signaling
2.14 3.43e-02 GO:0007167 enzyme linked receptor protein signaling pathway
2.16 3.51e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.03 3.78e-02 GO:0007267 cell-cell signaling
2.83 4.02e-02 GO:0051960 regulation of nervous system development
1.93 4.05e-02 GO:0031324 negative regulation of cellular metabolic process
3.12 4.16e-02 GO:0043193 positive regulation of gene-specific transcription
2.54 4.23e-02 GO:0051056 regulation of small GTPase mediated signal transduction
4.67 4.28e-02 GO:0045637 regulation of myeloid cell differentiation
1.88 4.54e-02 GO:0009605 response to external stimulus
2.13 4.71e-02 GO:0001932 regulation of protein phosphorylation
1.99 4.98e-02 GO:0031399 regulation of protein modification process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
3.05 2.30e-06 GO:0045202 synapse
2.91 1.94e-05 GO:0043005 neuron projection
2.90 8.78e-04 GO:0044456 synapse part
1.57 1.84e-03 GO:0044459 plasma membrane part
1.35 8.88e-03 GO:0005886 plasma membrane
1.34 1.24e-02 GO:0071944 cell periphery
5.57 2.12e-02 GO:0044309 neuron spine
26.12 2.36e-02 GO:0042583 chromaffin granule
26.12 2.36e-02 GO:0042584 chromaffin granule membrane
3.30 2.50e-02 GO:0045211 postsynaptic membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.51 1.30e-09 GO:0001071 nucleic acid binding transcription factor activity
2.51 1.30e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
2.34 8.21e-08 GO:0030528 transcription regulator activity
2.60 6.61e-07 GO:0043565 sequence-specific DNA binding
2.94 4.28e-04 GO:0016563 transcription activator activity
6.45 1.12e-03 GO:0004879 ligand-dependent nuclear receptor activity
1.26 1.16e-03 GO:0005515 protein binding
3.28 2.59e-03 GO:0000975 regulatory region DNA binding
3.28 2.59e-03 GO:0001067 regulatory region nucleic acid binding
3.28 2.59e-03 GO:0044212 transcription regulatory region DNA binding
8.71 4.46e-03 GO:0008066 glutamate receptor activity
6.15 5.33e-03 GO:0003707 steroid hormone receptor activity
1.86 6.31e-03 GO:0005102 receptor binding
1.13 1.12e-02 GO:0005488 binding
2.68 1.23e-02 GO:0008134 transcription factor binding
2.83 1.28e-02 GO:0003702 RNA polymerase II transcription factor activity
3.05 1.96e-02 GO:0010843 promoter binding
10.88 2.63e-02 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity