Motif ID: CCAGUGU

Z-value: 0.996


Mature miRNA associated with seed CCAGUGU:

NamemiRBase Accession
hsa-miR-199a-5p MIMAT0000231
hsa-miR-199b-5p MIMAT0000263



Activity profile for motif CCAGUGU.

activity profile for motif CCAGUGU


Sorted Z-values histogram for motif CCAGUGU

Sorted Z-values for motif CCAGUGU



Network of associatons between targets according to the STRING database.



First level regulatory network of CCAGUGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_116166346 27.406 NM_001172896
NM_001172897
CAV1

caveolin 1, caveolae protein, 22kDa

chr7_+_116164838 26.999 NM_001753
CAV1
caveolin 1, caveolae protein, 22kDa
chr7_+_116165043 26.034 NM_001172895
CAV1
caveolin 1, caveolae protein, 22kDa
chrX_-_99891690 17.544 NM_003270
TSPAN6
tetraspanin 6
chr1_-_94703252 15.588 NM_004815
ARHGAP29
Rho GTPase activating protein 29
chr1_+_182992329 14.033 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr17_+_48133331 13.508 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr12_+_13043955 12.630 NM_003979
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr8_+_104310660 12.246 NM_001164615
FZD6
frizzled family receptor 6
chr8_+_104311058 12.162 NM_001164616
NM_003506
FZD6

frizzled family receptor 6

chr7_+_100770378 11.827 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr6_+_30851860 11.546 NM_001954
DDR1
discoidin domain receptor tyrosine kinase 1
chr7_-_131241321 10.455 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr6_+_30852326 10.375 NM_013993
DDR1
discoidin domain receptor tyrosine kinase 1
chr6_+_30852756 10.252 NM_001202523
DDR1
discoidin domain receptor tyrosine kinase 1
chr6_+_30856462 10.201 NM_001202521
NM_001202522
NM_013994
DDR1


discoidin domain receptor tyrosine kinase 1


chr1_+_19969722 9.698 NM_182744
NBL1
neuroblastoma, suppression of tumorigenicity 1
chr1_+_19972259 9.459 NM_001204086
NBL1
neuroblastoma, suppression of tumorigenicity 1
chr7_+_872137 9.318 NM_001130965
SUN1
Sad1 and UNC84 domain containing 1
chr1_+_19970207 8.869 NM_001204084
NBL1
neuroblastoma, suppression of tumorigenicity 1
chr1_+_19971865 8.851 NM_001204085
NBL1
neuroblastoma, suppression of tumorigenicity 1
chr8_-_12973752 8.503 NM_001164271
DLC1
deleted in liver cancer 1
chr4_-_40517913 8.383 NM_019027
RBM47
RNA binding motif protein 47
chr2_-_242255114 8.349 NM_005336
HDLBP
high density lipoprotein binding protein
chr1_+_19970674 7.976 NM_005380
NBL1
neuroblastoma, suppression of tumorigenicity 1
chr8_-_12990731 7.836 NM_006094
DLC1
deleted in liver cancer 1
chr19_-_11308184 7.396 NM_001136191
KANK2
KN motif and ankyrin repeat domains 2
chr5_-_179233772 7.208 NM_014275
MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr17_-_15165873 7.151 NM_153321
PMP22
peripheral myelin protein 22
chr17_-_15168590 6.956 NM_000304
PMP22
peripheral myelin protein 22
chr8_+_98881277 6.940 NM_002380
NM_030583
MATN2

matrilin 2

chr3_+_180630054 6.895 NM_001013438
NM_001013439
NM_005087
FXR1


fragile X mental retardation, autosomal homolog 1


chr19_-_11305186 6.881 NM_015493
KANK2
KN motif and ankyrin repeat domains 2
chr9_-_128003634 6.703 NM_005347
HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr8_+_30241943 6.427 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr17_-_15164043 6.360 NM_153322
PMP22
peripheral myelin protein 22
chr17_-_46682333 6.280 NM_018952
HOXB6
homeobox B6
chr16_+_55515468 6.266 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr5_+_68530621 6.177 NM_001799
CDK7
cyclin-dependent kinase 7
chr2_+_36583369 6.116 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr5_-_179229874 6.068 NM_054013
MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr15_-_77363519 6.006 NM_001168412
NM_005724
NM_198902
TSPAN3


tetraspanin 3


chr9_+_110045516 5.870 NM_002874
RAD23B
RAD23 homolog B (S. cerevisiae)
chr12_-_54653317 5.831 NM_001127322
CBX5
chromobox homolog 5
chr17_+_55163077 5.534 NM_001242903
NM_001242902
AKAP1

A kinase (PRKA) anchor protein 1

chr2_-_47143250 5.525 NM_001171507
NM_001171510
MCFD2

multiple coagulation factor deficiency 2

chr16_+_55512801 5.477 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr19_+_11649578 5.447 NM_001299
CNN1
calponin 1, basic, smooth muscle
chr6_+_43737937 5.440 NM_001025366
NM_001025367
NM_001025368
NM_001025369
NM_001025370
NM_001033756
NM_001171622
NM_001171623
NM_001171624
NM_001171625
NM_001171626
NM_001171627
NM_001171628
NM_001171629
NM_001171630
NM_001204384
NM_001204385
NM_003376
VEGFA

















vascular endothelial growth factor A

















chr2_-_47142950 5.410 NM_001171506
NM_001171509
NM_139279
MCFD2


multiple coagulation factor deficiency 2


chr10_+_70883856 5.316 NM_001035260
NM_004896
VPS26A

vacuolar protein sorting 26 homolog A (S. pombe)

chr17_+_55162530 5.310 NM_003488
AKAP1
A kinase (PRKA) anchor protein 1
chr12_-_120687956 5.258 NM_025157
PXN
paxillin
chr14_+_62162042 5.251 NM_001530
NM_181054
HIF1A

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

chr12_-_54653369 5.236 NM_001127321
CBX5
chromobox homolog 5
chr2_-_242212244 5.221 NM_001243900
NM_203346
HDLBP

high density lipoprotein binding protein

chr12_-_120703549 5.167 NM_001080855
NM_001243756
NM_002859
PXN


paxillin


chr4_-_40631846 5.079 NM_001098634
RBM47
RNA binding motif protein 47
chr2_-_47168902 4.987 NM_001171508
NM_001171511
MCFD2

multiple coagulation factor deficiency 2

chr8_-_93029864 4.790 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_153573858 4.760 NM_017892
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr20_-_10654429 4.724 NM_000214
JAG1
jagged 1
chr20_-_62601140 4.585 NM_020713
ZNF512B
zinc finger protein 512B
chr6_+_21593963 4.574 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr11_-_102323353 4.529 NM_052932
TMEM123
transmembrane protein 123
chr7_-_50800018 4.286 NM_001001549
NM_005311
GRB10

growth factor receptor-bound protein 10

chrX_+_23801274 4.137 NM_002970
SAT1
spermidine/spermine N1-acetyltransferase 1
chr16_+_31483066 4.134 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr7_-_50772997 3.974 NM_001001550
GRB10
growth factor receptor-bound protein 10
chr14_+_67707825 3.859 NM_022474
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr11_-_86666211 3.793 NM_012193
FZD4
frizzled family receptor 4
chr7_+_144052432 3.791 NM_005435
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr11_+_12399024 3.559 NM_018222
PARVA
parvin, alpha
chr2_-_101767714 3.502 NM_001102426
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr17_+_40761357 3.491 NM_001070
TUBG1
tubulin, gamma 1
chr17_-_47439326 3.465 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr1_+_19923457 3.375 NM_001204088
NM_001204089
NM_001032363
NM_001204082
NM_001204083
C1orf151-NBL1

MINOS1


C1orf151-NBL1 readthrough

mitochondrial inner membrane organizing system 1


chr9_-_107690526 3.336 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr7_-_50861114 3.317 NM_001001555
GRB10
growth factor receptor-bound protein 10
chr16_+_31484497 3.286 NM_015927
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr5_+_154320628 3.285 NM_001014990
NM_014180
MRPL22

mitochondrial ribosomal protein L22

chr3_-_176915012 3.221 NM_024665
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr4_+_140222668 3.161 NM_057175
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr19_+_45312294 3.083 NM_001013257
NM_005581
BCAM

basal cell adhesion molecule (Lutheran blood group)

chr10_-_101945787 3.080 NM_001100626
ERLIN1
ER lipid raft associated 1
chr17_-_35656691 3.042 NM_198837
NM_198838
ACACA

acetyl-CoA carboxylase alpha

chr3_+_141043054 2.881 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr2_-_39664129 2.851 NM_003618
MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr10_-_101945686 2.748 NM_006459
ERLIN1
ER lipid raft associated 1
chr11_+_86748870 2.724 NM_001168724
NM_022918
TMEM135

transmembrane protein 135

chr15_-_42264749 2.724 NM_139265
EHD4
EH-domain containing 4
chrX_-_73834460 2.658 NM_016120
NM_183353
RLIM

ring finger protein, LIM domain interacting

chr19_+_45349392 2.653 NM_001042724
NM_002856
PVRL2

poliovirus receptor-related 2 (herpesvirus entry mediator B)

chr22_-_36784055 2.574 NM_002473
MYH9
myosin, heavy chain 9, non-muscle
chr20_+_11898536 2.560 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr1_+_89149836 2.527 NM_006256
PKN2
protein kinase N2
chrX_-_77150907 2.471 NM_032121
MAGT1
magnesium transporter 1
chr12_+_50478942 2.461 NM_003076
NM_139071
SMARCD1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1

chr16_-_52581713 2.456 NM_001146188
TOX3
TOX high mobility group box family member 3
chr8_+_70405027 2.447 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr6_-_132272311 2.399 NM_001901
CTGF
connective tissue growth factor
chr14_-_35099296 2.397 NM_021249
NM_152233
SNX6

sorting nexin 6

chr17_+_45727274 2.363 NM_002265
KPNB1
karyopherin (importin) beta 1
chr12_+_109535922 2.354 NM_003362
UNG
uracil-DNA glycosylase
chr2_+_101436491 2.333 NM_002518
NPAS2
neuronal PAS domain protein 2
chr12_+_109535377 2.307 NM_080911
UNG
uracil-DNA glycosylase
chr1_-_24127157 2.298 NM_001008216
GALE
UDP-galactose-4-epimerase
chr10_-_98346793 2.279 NM_020123
TM9SF3
transmembrane 9 superfamily member 3
chr11_+_9406123 2.251 NM_006391
IPO7
importin 7
chr17_-_39968450 2.232 NM_006455
LEPREL4
leprecan-like 4
chr2_+_241938254 2.203 NM_001080437
SNED1
sushi, nidogen and EGF-like domains 1
chr17_-_35766762 2.198 NM_198834
NM_198839
ACACA

acetyl-CoA carboxylase alpha

chr11_+_34073188 2.178 NM_005898
NM_203364
CAPRIN1

cell cycle associated protein 1

chr12_+_52347163 2.158 NM_020327
ACVR1B
activin A receptor, type IB
chr19_+_39616384 2.130 NM_001014831
NM_001014832
NM_001014834
NM_001014835
NM_005884
PAK4




p21 protein (Cdc42/Rac)-activated kinase 4




chr12_-_122907083 2.124 NM_001247997
NM_002956
NM_198240
CLIP1


CAP-GLY domain containing linker protein 1


chr6_+_10555948 2.117 NM_001491
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr6_+_10585978 2.082 NM_145655
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr12_-_54673901 2.076 NM_012117
CBX5
chromobox homolog 5
chr12_+_102271082 1.996 NM_018370
DRAM1
DNA-damage regulated autophagy modulator 1
chr1_+_28764660 1.991 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr8_-_93107442 1.977 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr7_+_130794854 1.966 NM_001145354
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr17_+_43224683 1.958 NM_006460
HEXIM1
hexamethylene bis-acetamide inducible 1
chr20_+_19870209 1.930 NM_018993
RIN2
Ras and Rab interactor 2
chr1_-_24126031 1.917 NM_001127621
GALE
UDP-galactose-4-epimerase
chr12_+_50794591 1.907 NM_001170803
NM_001170804
NM_001170808
NM_052879
NM_199188
NM_199190
LARP4





La ribonucleoprotein domain family, member 4





chr3_-_189840225 1.894 NM_001134418
LEPREL1
leprecan-like 1
chr17_+_35849950 1.884 NM_007026
DUSP14
dual specificity phosphatase 14
chr12_+_104609501 1.866 NM_001093771
TXNRD1
thioredoxin reductase 1
chr12_+_104680712 1.844 NM_003330
NM_182729
NM_182742
NM_182743
TXNRD1



thioredoxin reductase 1



chr5_-_83016850 1.836 NM_001884
HAPLN1
hyaluronan and proteoglycan link protein 1
chr8_+_110346549 1.832 NM_001193557
NM_020189
ENY2

enhancer of yellow 2 homolog (Drosophila)

chr1_+_166808721 1.828 NM_017542
POGK
pogo transposable element with KRAB domain
chr17_+_46125675 1.819 NM_003204
NFE2L1
nuclear factor (erythroid-derived 2)-like 1
chr17_-_4269814 1.801 NM_003342
UBE2G1
ubiquitin-conjugating enzyme E2G 1
chr3_-_183273407 1.795 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr16_-_71842892 1.783 NM_001030007
NM_001128
AP1G1

adaptor-related protein complex 1, gamma 1 subunit

chr20_+_19867075 1.759 NM_001242581
RIN2
Ras and Rab interactor 2
chr13_-_24007822 1.748 NM_014363
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr3_-_189838907 1.668 NM_018192
LEPREL1
leprecan-like 1
chr3_-_160283361 1.621 NM_002268
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr14_+_92788924 1.620 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr1_+_13910251 1.604 NM_006474
NM_198389
PDPN

podoplanin

chr5_+_179921371 1.601 NM_015455
CNOT6
CCR4-NOT transcription complex, subunit 6
chr11_-_27528298 1.597 NM_018362
LIN7C
lin-7 homolog C (C. elegans)
chr7_+_856251 1.575 NM_001171944
NM_001171945
NM_025154
SUN1


Sad1 and UNC84 domain containing 1


chr1_-_24126891 1.559 NM_000403
GALE
UDP-galactose-4-epimerase
chr2_-_70781146 1.556 NM_001099691
NM_003236
TGFA

transforming growth factor, alpha

chr2_+_70485204 1.546 NM_016297
PCYOX1
prenylcysteine oxidase 1
chr16_-_30798206 1.546 NM_001080417
ZNF629
zinc finger protein 629
chr1_+_28696056 1.542 NM_001048183
PHACTR4
phosphatase and actin regulator 4
chr2_+_109335906 1.537 NM_006267
RANBP2
RAN binding protein 2
chr21_+_40177847 1.536 NM_005239
ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr5_+_149887673 1.532 NM_001543
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr3_-_125094003 1.532 NM_021964
ZNF148
zinc finger protein 148
chr10_-_71930185 1.526 NM_001142648
NM_020150
SAR1A

SAR1 homolog A (S. cerevisiae)

chr5_-_176778683 1.524 NM_006816
LMAN2
lectin, mannose-binding 2
chr15_-_34394016 1.494 NM_020154
C15orf24
chromosome 15 open reading frame 24
chr1_-_205719340 1.471 NM_022731
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr11_-_57298180 1.445 NM_012456
TIMM10
translocase of inner mitochondrial membrane 10 homolog (yeast)
chr18_-_54305839 1.439 NM_004786
TXNL1
thioredoxin-like 1
chr12_+_72148653 1.432 NM_014999
RAB21
RAB21, member RAS oncogene family
chr1_+_212788359 1.429 NM_001206486
ATF3
activating transcription factor 3
chr1_+_212738675 1.428 NM_001030287
ATF3
activating transcription factor 3
chr1_+_218518675 1.396 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr8_-_77913279 1.388 NM_001172086
NM_001172087
PEX2

peroxisomal biogenesis factor 2

chr1_+_13911966 1.373 NM_001006624
NM_001006625
PDPN

podoplanin

chr3_-_195270004 1.359 NM_006241
PPP1R2
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr2_+_170590241 1.358 NM_144711
KLHL23
kelch-like 23 (Drosophila)
chr11_-_62414096 1.337 NM_198334
NM_198335
GANAB

glucosidase, alpha; neutral AB

chr12_-_46766563 1.329 NM_018976
SLC38A2
solute carrier family 38, member 2
chr8_-_77912296 1.315 NM_000318
NM_001079867
PEX2

peroxisomal biogenesis factor 2

chr7_-_105162551 1.309 NM_019042
PUS7
pseudouridylate synthase 7 homolog (S. cerevisiae)
chr1_-_214724974 1.304 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr16_+_16043206 1.300 NM_004996
NM_019862
NM_019898
NM_019899
NM_019900
ABCC1




ATP-binding cassette, sub-family C (CFTR/MRP), member 1




chrX_+_40944858 1.297 NM_001039590
NM_001039591
USP9X

ubiquitin specific peptidase 9, X-linked

chrX_-_77395108 1.296 NM_015975
TAF9B
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
chr20_-_24973410 1.279 NM_020531
C20orf3
chromosome 20 open reading frame 3
chr12_-_56652118 1.239 NM_173595
ANKRD52
ankyrin repeat domain 52
chr1_+_212781969 1.235 NM_001040619
NM_001206484
NM_001206488
NM_001674
ATF3



activating transcription factor 3



chr1_-_145826928 1.201 NM_001097612
NM_001097613
GPR89B
GPR89A

G protein-coupled receptor 89B
G protein-coupled receptor 89A

chr9_-_127952037 1.192 NM_001123355
NM_001123369
NM_002721
PPP6C


protein phosphatase 6, catalytic subunit


chr20_+_11871364 1.188 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr2_+_178257371 1.177 NM_003659
AGPS
alkylglycerone phosphate synthase
chr20_-_25566137 1.169 NM_025176
NINL
ninein-like
chr19_+_11925077 1.144 NM_152357
ZNF440
zinc finger protein 440
chr7_-_134855530 1.143 NM_001243749
NM_001243751
NM_001243754
NM_024033
C7orf49



chromosome 7 open reading frame 49



chr9_-_94186140 1.137 NM_005384
NFIL3
nuclear factor, interleukin 3 regulated
chr17_-_56065596 1.090 NM_007146
VEZF1
vascular endothelial zinc finger 1
chrX_+_128674181 1.076 NM_000276
NM_001587
OCRL

oculocerebrorenal syndrome of Lowe

chr1_-_155881163 1.074 NM_006912
RIT1
Ras-like without CAAX 1
chr16_+_57673206 1.063 NM_001145774
GPR56
G protein-coupled receptor 56
chr8_-_102217868 1.056 NM_001042511
ZNF706
zinc finger protein 706
chr8_-_102217907 1.032 NM_001042510
NM_016096
ZNF706

zinc finger protein 706

chr20_-_48184652 1.029 NM_000961
PTGIS
prostaglandin I2 (prostacyclin) synthase
chr3_+_63884074 1.027 NM_001177387
ATXN7
ataxin 7
chr22_-_18507151 1.022 NM_001122731
NM_001136004
NM_015241
MICAL3


microtubule associated monoxygenase, calponin and LIM domain containing 3


chr12_-_4754275 1.010 NM_006422
AKAP3
A kinase (PRKA) anchor protein 3
chr3_+_50192847 1.006 NM_004186
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.38 8.64e-06 GO:0065007 biological regulation
1.39 3.70e-05 GO:0050789 regulation of biological process
1.40 5.15e-05 GO:0050794 regulation of cellular process
1.58 5.56e-05 GO:0044260 cellular macromolecule metabolic process
1.23 6.76e-05 GO:0009987 cellular process
2.17 1.31e-04 GO:0009966 regulation of signal transduction
2.03 3.45e-04 GO:0023051 regulation of signaling
2.88 2.09e-03 GO:0010647 positive regulation of cell communication
4.16 2.35e-03 GO:0048514 blood vessel morphogenesis
2.22 2.71e-03 GO:0010646 regulation of cell communication
2.09 2.96e-03 GO:0051641 cellular localization
1.86 3.06e-03 GO:0048583 regulation of response to stimulus
2.17 3.48e-03 GO:0051649 establishment of localization in cell
1.44 4.42e-03 GO:0043170 macromolecule metabolic process
3.56 4.95e-03 GO:0001944 vasculature development
2.36 6.39e-03 GO:0051128 regulation of cellular component organization
1.76 6.73e-03 GO:0048523 negative regulation of cellular process
3.62 7.41e-03 GO:0001568 blood vessel development
2.75 7.42e-03 GO:0023056 positive regulation of signaling
52.94 8.76e-03 GO:0032927 positive regulation of activin receptor signaling pathway
2.78 9.31e-03 GO:0009967 positive regulation of signal transduction
1.35 1.59e-02 GO:0044237 cellular metabolic process
2.09 2.04e-02 GO:0008104 protein localization
1.65 2.82e-02 GO:0048522 positive regulation of cellular process
1.65 3.43e-02 GO:0048519 negative regulation of biological process
1.63 3.47e-02 GO:0044267 cellular protein metabolic process
2.71 3.48e-02 GO:0072358 cardiovascular system development
2.71 3.48e-02 GO:0072359 circulatory system development
1.93 3.85e-02 GO:0033036 macromolecule localization
2.60 4.28e-02 GO:0034613 cellular protein localization
7.57 4.64e-02 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
2.58 4.72e-02 GO:0070727 cellular macromolecule localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.20 1.12e-04 GO:0005622 intracellular
1.18 1.63e-03 GO:0044424 intracellular part
1.26 3.18e-03 GO:0005737 cytoplasm
2.12 3.63e-03 GO:0005794 Golgi apparatus
1.20 1.31e-02 GO:0043229 intracellular organelle
1.20 1.50e-02 GO:0043226 organelle
3.91 3.23e-02 GO:0005912 adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.39 3.25e-06 GO:0005515 protein binding
3.49 4.08e-05 GO:0003712 transcription cofactor activity
3.48 4.29e-05 GO:0000988 protein binding transcription factor activity
3.48 4.29e-05 GO:0000989 transcription factor binding transcription factor activity
30.25 1.35e-03 GO:0017002 activin receptor activity
19.25 1.20e-02 GO:0048185 activin binding
1.15 1.82e-02 GO:0005488 binding
5.73 2.48e-02 GO:0042393 histone binding
4.02 3.24e-02 GO:0003714 transcription corepressor activity