Motif ID: CCCUGAG

Z-value: 2.070


Mature miRNA associated with seed CCCUGAG:

NamemiRBase Accession
hsa-miR-125a-5p MIMAT0000443
hsa-miR-125b MIMAT0000423
hsa-miR-4319 MIMAT0016870



Activity profile for motif CCCUGAG.

activity profile for motif CCCUGAG


Sorted Z-values histogram for motif CCCUGAG

Sorted Z-values for motif CCCUGAG



Network of associatons between targets according to the STRING database.



First level regulatory network of CCCUGAG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_31619043 38.547 NM_015995
KLF13
Kruppel-like factor 13
chr6_+_138188352 28.764 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr20_+_55966440 24.322 NM_017495
NM_183425
RBM38

RNA binding motif protein 38

chr16_-_28936454 23.963 NM_024816
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr22_-_39548448 23.746 NM_175709
CBX7
chromobox homolog 7
chrX_+_64708614 23.582 NM_001010888
ZC3H12B
zinc finger CCCH-type containing 12B
chr4_-_2263706 23.410 NM_006454
MXD4
MAX dimerization protein 4
chr3_-_57678594 22.351 NM_152678
FAM116A
family with sequence similarity 116, member A
chr2_+_30454396 21.877 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr17_-_61777478 21.509 NM_030576
LIMD2
LIM domain containing 2
chr15_-_61521478 20.815 NM_134261
RORA
RAR-related orphan receptor A
chr14_+_69865380 20.568 NM_001252148
NM_001252150
NM_018375
SLC39A9


solute carrier family 39 (zinc transporter), member 9


chr2_-_206950895 20.522 NM_017759
INO80D
INO80 complex subunit D
chr3_+_186648273 20.234 NM_173216
NM_173217
ST6GAL1

ST6 beta-galactosamide alpha-2,6-sialyltranferase 1

chr3_+_186739643 20.137 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr22_-_44258210 19.898 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr19_-_18632886 19.617 NM_006532
ELL
elongation factor RNA polymerase II
chr8_+_38034066 19.445 NM_001204878
NM_004874
BAG4

BCL2-associated athanogene 4

chr19_+_7968764 18.747 NM_145185
MAP2K7
mitogen-activated protein kinase kinase 7
chr19_+_42387249 18.388 NM_004706
NM_198977
ARHGEF1

Rho guanine nucleotide exchange factor (GEF) 1

chr17_+_18218569 17.924 NM_144775
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr17_-_76778306 16.916 NM_004762
NM_017456
CYTH1

cytohesin 1

chr15_-_60884615 16.892 NM_134262
RORA
RAR-related orphan receptor A
chr12_-_6665220 16.832 NM_001039670
NM_001193457
NM_080730
IFFO1


intermediate filament family orphan 1


chr17_-_66287256 16.644 NM_001174166
NM_004694
SLC16A6

solute carrier family 16, member 6 (monocarboxylic acid transporter 7)

chr15_-_90358057 16.513 NM_001150
ANPEP
alanyl (membrane) aminopeptidase
chr19_+_4969123 16.505 NM_015015
KDM4B
lysine (K)-specific demethylase 4B
chr12_-_120806893 16.417 NM_002442
MSI1
musashi homolog 1 (Drosophila)
chr1_+_26856240 16.323 NM_002953
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr17_-_8093492 16.290 NM_017622
C17orf59
chromosome 17 open reading frame 59
chr19_+_42388445 16.220 NM_199002
ARHGEF1
Rho guanine nucleotide exchange factor (GEF) 1
chr15_+_81589240 16.194 NM_004513
IL16
interleukin 16
chr6_-_24911194 16.111 NM_014722
FAM65B
family with sequence similarity 65, member B
chr15_+_74833517 16.083 NM_006465
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr1_-_156470506 15.999 NM_005920
MEF2D
myocyte enhancer factor 2D
chr11_+_117857062 15.949 NM_001558
IL10RA
interleukin 10 receptor, alpha
chr16_-_2264776 15.728 NM_001042371
PGP
phosphoglycolate phosphatase
chr17_+_61699786 15.718 NM_002401
NM_203351
MAP3K3

mitogen-activated protein kinase kinase kinase 3

chr9_-_123476578 15.714 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr19_-_4723814 15.471 NM_139159
DPP9
dipeptidyl-peptidase 9
chr3_+_5229357 15.424 NM_014674
EDEM1
ER degradation enhancer, mannosidase alpha-like 1
chr15_-_79383080 15.380 NM_001145648
NM_002891
RASGRF1

Ras protein-specific guanine nucleotide-releasing factor 1

chr6_+_138483024 15.339 NM_020340
KIAA1244
KIAA1244
chr22_+_45705766 15.261 NM_017911
FAM118A
family with sequence similarity 118, member A
chr15_-_23086290 15.088 NM_144599
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr12_-_51717905 14.961 NM_016293
BIN2
bridging integrator 2
chr11_-_128392061 14.937 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr3_+_58223228 14.923 NM_020676
ABHD6
abhydrolase domain containing 6
chr1_+_12227050 14.859 NM_001066
TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr7_-_139876718 14.848 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr4_+_95679075 14.839 NM_001203
BMPR1B
bone morphogenetic protein receptor, type IB
chr11_-_128457452 14.822 NM_001143820
ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr11_-_117102810 14.821 NM_004716
PCSK7
proprotein convertase subtilisin/kexin type 7
chrX_-_103401607 14.662 NM_001012755
MCART6
mitochondrial carrier triple repeat 6
chr10_-_5708542 14.280 NM_024701
ASB13
ankyrin repeat and SOCS box containing 13
chr19_-_19754452 14.090 NM_016573
GMIP
GEM interacting protein
chr3_+_183353355 14.067 NM_017644
KLHL24
kelch-like 24 (Drosophila)
chr11_+_67033889 13.859 NM_001619
ADRBK1
adrenergic, beta, receptor kinase 1
chr2_+_74273449 13.844 NM_144993
TET3
tet methylcytosine dioxygenase 3
chr9_-_92094610 13.757 NM_001142287
NM_006378
SEMA4D

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D

chr6_+_106546736 13.592 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr3_+_47021146 13.369 NM_015175
NBEAL2
neurobeachin-like 2
chr1_-_23857711 13.307 NM_004091
E2F2
E2F transcription factor 2
chr15_+_85923739 13.182 NM_006738
NM_007200
AKAP13

A kinase (PRKA) anchor protein 13

chr16_+_4897911 13.180 NM_001079514
UBN1
ubinuclein 1
chr1_+_9711781 13.132 NM_005026
PIK3CD
phosphoinositide-3-kinase, catalytic, delta polypeptide
chr4_-_25032306 12.990 NM_018176
LGI2
leucine-rich repeat LGI family, member 2
chr17_-_40333190 12.784 NM_012285
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr1_+_203274646 12.680 NM_006763
BTG2
BTG family, member 2
chr18_+_55102777 12.630 NM_004852
ONECUT2
one cut homeobox 2
chr8_-_67579446 12.196 NM_025054
VCPIP1
valosin containing protein (p97)/p47 complex interacting protein 1
chr2_-_213403280 12.193 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr14_+_56584854 12.147 NM_021255
PELI2
pellino homolog 2 (Drosophila)
chr15_+_81517639 12.134 NM_172217
IL16
interleukin 16
chr9_-_100954883 12.108 NM_052820
CORO2A
coronin, actin binding protein, 2A
chr9_+_140772228 11.977 NM_000718
NM_001243812
CACNA1B

calcium channel, voltage-dependent, N type, alpha 1B subunit

chr15_+_81489218 11.934 NM_001172128
IL16
interleukin 16
chr19_-_37701385 11.798 NM_152279
ZNF585B
zinc finger protein 585B
chr15_-_77712436 11.692 NM_024776
PEAK1
NKF3 kinase family member
chr8_-_74791098 11.662 NM_001001481
NM_018299
UBE2W

ubiquitin-conjugating enzyme E2W (putative)

chr6_+_35227478 11.638 NM_003427
ZNF76
zinc finger protein 76
chr3_-_13461802 11.531 NM_024923
NUP210
nucleoporin 210kDa
chr12_+_11802726 11.355 NM_001987
ETV6
ets variant 6
chr22_+_21771661 11.338 NM_015094
HIC2
hypermethylated in cancer 2
chr19_-_11450254 11.323 NM_004283
RAB3D
RAB3D, member RAS oncogene family
chr18_+_32558207 11.276 NM_001143827
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr14_-_21945031 11.247 NM_032846
RAB2B
RAB2B, member RAS oncogene family
chr17_-_37844266 11.237 NM_033419
PGAP3
post-GPI attachment to proteins 3
chr11_-_65381641 11.226 NM_002419
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr5_-_175964223 11.164 NM_014901
RNF44
ring finger protein 44
chr15_-_60919642 11.133 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr16_-_23521803 11.037 NM_015044
GGA2
golgi-associated, gamma adaptin ear containing, ARF binding protein 2
chr1_+_178694273 10.959 NM_152663
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr14_-_21944826 10.826 NM_001163380
RAB2B
RAB2B, member RAS oncogene family
chr6_-_90062610 10.707 NM_016021
UBE2J1
ubiquitin-conjugating enzyme E2, J1, U
chr6_+_106534188 10.695 NM_001198
PRDM1
PR domain containing 1, with ZNF domain
chr16_-_18937722 10.691 NM_015092
SMG1
smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr2_-_99347588 10.690 NM_012214
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr1_-_211307314 10.613 NM_002238
NM_172362
KCNH1

potassium voltage-gated channel, subfamily H (eag-related), member 1

chr6_+_11538486 10.364 NM_001100829
TMEM170B
transmembrane protein 170B
chr1_-_202679415 10.058 NM_177402
SYT2
synaptotagmin II
chrX_-_131623994 10.037 NM_001170704
MBNL3
muscleblind-like 3 (Drosophila)
chr8_-_66753968 9.931 NM_001242318
PDE7A
phosphodiesterase 7A
chr17_-_46651809 9.834 NM_002146
HOXB3
homeobox B3
chr15_-_70390229 9.818 NM_001105192
NM_005078
NM_020908
TLE3


transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)


chr14_-_88789531 9.801 NM_138317
KCNK10
potassium channel, subfamily K, member 10
chr22_+_45704821 9.777 NM_001104595
FAM118A
family with sequence similarity 118, member A
chr18_-_43652153 9.776 NM_024430
PSTPIP2
proline-serine-threonine phosphatase interacting protein 2
chr14_+_70078309 9.733 NM_014734
KIAA0247
KIAA0247
chr8_-_41754244 9.682 NM_001142446
ANK1
ankyrin 1, erythrocytic
chr2_-_74710356 9.626 NM_032779
CCDC142
coiled-coil domain containing 142
chr22_+_41777932 9.394 NM_003216
TEF
thyrotrophic embryonic factor
chr1_+_182758583 9.385 NM_001200050
NM_001200051
NM_001200052
NM_001200056
NM_030769
NPL




N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)




chr4_+_75858205 9.369 NM_015393
PARM1
prostate androgen-regulated mucin-like protein 1
chr16_+_4902076 9.361 NM_016936
UBN1
ubinuclein 1
chr13_-_73356070 9.336 NM_001128226
NM_014953
DIS3

DIS3 mitotic control homolog (S. cerevisiae)

chr18_+_48556483 9.323 NM_005359
SMAD4
SMAD family member 4
chr7_-_143059696 9.297 NM_001031690
FAM131B
family with sequence similarity 131, member B
chr6_+_391738 9.283 NM_001195286
NM_002460
IRF4

interferon regulatory factor 4

chr11_+_63606346 9.102 NM_001039469
NM_001163296
NM_001163297
NM_004954
MARK2



MAP/microtubule affinity-regulating kinase 2



chr1_+_151584514 9.100 NM_030918
SNX27
sorting nexin family member 27
chr18_+_32556891 9.013 NM_001143826
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr11_-_119234859 8.973 NM_171997
USP2
ubiquitin specific peptidase 2
chr5_+_56110899 8.871 NM_005921
MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr7_-_143059144 8.621 NM_014690
FAM131B
family with sequence similarity 131, member B
chr2_+_131113579 8.593 NM_001142370
NM_014369
PTPN18

protein tyrosine phosphatase, non-receptor type 18 (brain-derived)

chr5_-_38556682 8.560 NM_001127671
LIFR
leukemia inhibitory factor receptor alpha
chr5_+_133861685 8.474 NM_015288
PHF15
PHD finger protein 15
chr3_+_49591897 8.468 NM_003458
BSN
bassoon (presynaptic cytomatrix protein)
chr18_+_32621299 8.456 NM_014268
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr5_-_159739482 8.430 NM_024565
CCNJL
cyclin J-like
chr15_+_86220267 8.303 NM_144767
AKAP13
A kinase (PRKA) anchor protein 13
chr7_+_2557496 8.294 NM_002304
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr19_-_5340700 8.267 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr3_-_50378238 8.255 NM_001206957
NM_007182
NM_170714
RASSF1


Ras association (RalGDS/AF-6) domain family member 1


chr9_-_72287097 8.223 NM_001163
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr1_+_78245306 8.146 NM_198549
FAM73A
family with sequence similarity 73, member A
chr11_+_1411089 8.067 NM_003957
BRSK2
BR serine/threonine kinase 2
chr20_+_35201948 7.958 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr5_-_37839781 7.942 NM_000514
GDNF
glial cell derived neurotrophic factor
chr4_+_72052354 7.922 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr11_+_71639767 7.917 NM_018320
RNF121
ring finger protein 121
chr15_-_73661604 7.887 NM_005477
HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chrX_+_153639868 7.868 NM_000116
NM_181311
NM_181312
NM_181313
TAZ



tafazzin



chr17_-_36956145 7.863 NM_003559
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr1_-_200992824 7.855 NM_001252100
NM_001252102
NM_001252103
NM_017596
KIF21B



kinesin family member 21B



chr10_-_103879933 7.810 NM_001113407
LDB1
LIM domain binding 1
chr1_-_212208779 7.771 NM_001199809
NM_001199811
NM_001199812
NM_015434
INTS7



integrator complex subunit 7



chr1_+_54519259 7.693 NM_153035
TCEANC2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr11_+_94277005 7.680 NM_002033
PIWIL4
FUT4
piwi-like 4 (Drosophila)
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr4_+_37455551 7.679 NM_001104629
C4orf19
chromosome 4 open reading frame 19
chr16_+_27561441 7.654 NM_015202
KIAA0556
KIAA0556
chr1_-_21616888 7.544 NM_001397
ECE1
endothelin converting enzyme 1
chr19_+_18794391 7.500 NM_001098482
NM_015321
CRTC1

CREB regulated transcription coactivator 1

chr4_+_7045142 7.440 NM_152293
TADA2B
transcriptional adaptor 2B
chr19_-_17799005 7.371 NM_001080421
UNC13A
unc-13 homolog A (C. elegans)
chr11_+_75526211 7.341 NM_003369
UVRAG
UV radiation resistance associated gene
chr20_+_34359904 7.336 NM_016436
PHF20
PHD finger protein 20
chr14_-_92572950 7.332 NM_001127696
NM_001127697
NM_001164774
NM_001164776
NM_001164777
NM_001164778
NM_001164779
NM_001164780
NM_001164781
NM_001164782
NM_004993
NM_030660
ATXN3











ataxin 3











chr19_-_4066739 7.241 NM_015898
ZBTB7A
zinc finger and BTB domain containing 7A
chr12_+_51632507 7.194 NM_001136264
NM_001136266
NM_001136267
NM_001136268
NM_001136269
NM_014764
DAZAP2





DAZ associated protein 2





chr12_-_42538432 7.107 NM_001099650
NM_173601
GXYLT1

glucoside xylosyltransferase 1

chr12_-_123380682 7.087 NM_024667
VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr7_-_98741681 7.064 NM_001199847
NM_020429
NM_181349
SMURF1


SMAD specific E3 ubiquitin protein ligase 1


chr13_-_29292961 7.053 NM_001135919
NM_181785
SLC46A3

solute carrier family 46, member 3

chr3_-_52090090 7.044 NM_001947
DUSP7
dual specificity phosphatase 7
chr12_+_53773924 7.032 NM_001251825
NM_138473
SP1

Sp1 transcription factor

chr3_+_9773427 7.012 NM_001003694
NM_004634
BRPF1

bromodomain and PHD finger containing, 1

chr3_-_50374875 6.978 NM_170713
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr9_-_115095933 6.974 NM_001163788
NM_001163790
NM_001244896
NM_001244897
NM_005156
PTBP3




polypyrimidine tract binding protein 3




chr3_+_185000714 6.919 NM_001242314
NM_001242317
MAP3K13

mitogen-activated protein kinase kinase kinase 13

chr1_-_150552127 6.899 NM_001197320
NM_021960
NM_182763
MCL1


myeloid cell leukemia sequence 1 (BCL2-related)


chr1_+_205197031 6.886 NM_014858
TMCC2
transmembrane and coiled-coil domain family 2
chr14_-_90085325 6.879 NM_001085471
FOXN3
forkhead box N3
chr3_-_133748828 6.806 NM_005630
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr3_+_15469052 6.799 NM_033083
EAF1
ELL associated factor 1
chr2_-_201936389 6.778 NM_173822
FAM126B
family with sequence similarity 126, member B
chr19_+_13261272 6.748 NM_004907
IER2
immediate early response 2
chr1_-_108507474 6.729 NM_006113
VAV3
vav 3 guanine nucleotide exchange factor
chr3_-_170626425 6.680 NM_020390
EIF5A2
eukaryotic translation initiation factor 5A2
chr3_+_46923738 6.642 NM_001184744
PTH1R
parathyroid hormone 1 receptor
chr20_+_35201854 6.624 NM_001199513
NM_001199514
TGIF2

TGFB-induced factor homeobox 2

chr20_+_54933982 6.620 NM_080821
FAM210B
family with sequence similarity 210, member B
chr17_+_21279667 6.618 NM_021012
KCNJ12
potassium inwardly-rectifying channel, subfamily J, member 12
chr14_+_102228134 6.595 NM_001161725
NM_001161726
PPP2R5C

protein phosphatase 2, regulatory subunit B', gamma

chr9_-_99382073 6.552 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr14_-_82000198 6.527 NM_001244984
NM_005065
SEL1L

sel-1 suppressor of lin-12-like (C. elegans)

chr4_+_38665587 6.515 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr2_+_61292999 6.513 NM_001129993
KIAA1841
KIAA1841
chr12_+_51818592 6.414 NM_001039960
NM_004858
SLC4A8

solute carrier family 4, sodium bicarbonate cotransporter, member 8

chr18_-_60986508 6.385 NM_000633
NM_000657
BCL2

B-cell CLL/lymphoma 2

chr21_-_40685697 6.384 NM_001007246
NM_018963
NM_033656
BRWD1


bromodomain and WD repeat domain containing 1


chr1_-_20834609 6.377 NM_024544
MUL1
mitochondrial E3 ubiquitin protein ligase 1
chr1_-_173176314 6.376 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr16_+_68298326 6.329 NM_001076785
NM_003983
SLC7A6

solute carrier family 7 (amino acid transporter light chain, y+L system), member 6

chr5_+_96294154 6.320 NM_175920
LNPEP
leucyl/cystinyl aminopeptidase
chr12_+_5019048 6.317 NM_000217
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr17_-_27224708 6.311 NM_004475
FLOT2
flotillin 2
chr19_-_2051222 6.303 NM_017572
NM_199054
MKNK2

MAP kinase interacting serine/threonine kinase 2

chr3_-_49823972 6.297 NM_001006115
NM_153273
IP6K1

inositol hexakisphosphate kinase 1


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.57 4.89e-11 GO:0023052 signaling
1.33 5.70e-09 GO:0050794 regulation of cellular process
1.30 1.80e-08 GO:0050789 regulation of biological process
1.80 2.74e-08 GO:0007166 cell surface receptor linked signaling pathway
1.61 6.21e-08 GO:0048518 positive regulation of biological process
1.53 6.71e-08 GO:0007165 signal transduction
1.27 2.61e-07 GO:0065007 biological regulation
2.33 9.67e-07 GO:0007167 enzyme linked receptor protein signaling pathway
1.44 9.93e-07 GO:0019222 regulation of metabolic process
1.60 1.77e-06 GO:0048522 positive regulation of cellular process
1.46 3.85e-06 GO:0031323 regulation of cellular metabolic process
1.56 5.58e-06 GO:0010468 regulation of gene expression
1.45 9.03e-06 GO:0080090 regulation of primary metabolic process
1.52 9.54e-06 GO:0048731 system development
2.42 9.84e-06 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.80 1.36e-05 GO:0035556 intracellular signal transduction
1.40 1.44e-05 GO:0051716 cellular response to stimulus
1.45 1.46e-05 GO:0007275 multicellular organismal development
1.42 1.59e-05 GO:0032502 developmental process
1.75 1.90e-05 GO:0007399 nervous system development
1.16 2.00e-05 GO:0009987 cellular process
1.58 2.01e-05 GO:0051252 regulation of RNA metabolic process
1.66 2.05e-05 GO:0006464 protein modification process
1.47 2.31e-05 GO:0048856 anatomical structure development
1.61 2.90e-05 GO:0030154 cell differentiation
1.98 2.93e-05 GO:0022008 neurogenesis
1.80 3.15e-05 GO:0051239 regulation of multicellular organismal process
1.69 3.80e-05 GO:0023051 regulation of signaling
1.64 3.88e-05 GO:0048583 regulation of response to stimulus
1.59 4.94e-05 GO:0048869 cellular developmental process
1.92 5.47e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.50 5.49e-05 GO:0009889 regulation of biosynthetic process
1.74 5.91e-05 GO:0009966 regulation of signal transduction
1.50 7.22e-05 GO:0031326 regulation of cellular biosynthetic process
2.45 7.55e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
1.78 9.51e-05 GO:0009893 positive regulation of metabolic process
1.49 1.21e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.43 1.31e-04 GO:0060255 regulation of macromolecule metabolic process
2.22 1.32e-04 GO:0048666 neuron development
1.60 1.35e-04 GO:0043412 macromolecule modification
1.96 1.37e-04 GO:0048699 generation of neurons
1.55 1.65e-04 GO:0006355 regulation of transcription, DNA-dependent
3.23 1.73e-04 GO:0043408 regulation of MAPKKK cascade
2.30 1.85e-04 GO:0000904 cell morphogenesis involved in differentiation
2.07 1.91e-04 GO:0030182 neuron differentiation
1.49 2.04e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.69 2.23e-04 GO:0009653 anatomical structure morphogenesis
2.02 2.48e-04 GO:2000026 regulation of multicellular organismal development
1.50 2.99e-04 GO:0010556 regulation of macromolecule biosynthetic process
2.35 3.41e-04 GO:0048812 neuron projection morphogenesis
2.13 4.49e-04 GO:0000902 cell morphogenesis
1.50 4.55e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.84 4.62e-04 GO:0006793 phosphorus metabolic process
1.84 4.62e-04 GO:0006796 phosphate metabolic process
1.77 4.65e-04 GO:0010604 positive regulation of macromolecule metabolic process
2.37 5.47e-04 GO:0007409 axonogenesis
2.23 8.61e-04 GO:0031175 neuron projection development
1.50 1.10e-03 GO:0042221 response to chemical stimulus
2.88 1.21e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.85 1.30e-03 GO:0050793 regulation of developmental process
1.87 1.35e-03 GO:0006351 transcription, DNA-dependent
2.19 1.42e-03 GO:0048858 cell projection morphogenesis
2.03 1.57e-03 GO:0030030 cell projection organization
1.83 1.77e-03 GO:0048468 cell development
1.99 1.81e-03 GO:0010628 positive regulation of gene expression
2.17 1.82e-03 GO:0032990 cell part morphogenesis
2.02 2.30e-03 GO:0032989 cellular component morphogenesis
2.27 3.24e-03 GO:0007243 intracellular protein kinase cascade
2.27 3.24e-03 GO:0023014 signal transduction via phosphorylation event
1.92 3.24e-03 GO:0006468 protein phosphorylation
1.62 3.48e-03 GO:0065009 regulation of molecular function
2.40 5.47e-03 GO:0007411 axon guidance
1.84 6.40e-03 GO:0048584 positive regulation of response to stimulus
2.44 8.05e-03 GO:0022603 regulation of anatomical structure morphogenesis
2.62 8.13e-03 GO:0000165 MAPKKK cascade
1.51 8.20e-03 GO:0048513 organ development
1.66 1.00e-02 GO:0031325 positive regulation of cellular metabolic process
1.81 1.03e-02 GO:0016310 phosphorylation
1.91 1.03e-02 GO:0045595 regulation of cell differentiation
1.91 1.35e-02 GO:0051254 positive regulation of RNA metabolic process
1.27 1.69e-02 GO:0043170 macromolecule metabolic process
1.93 1.78e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.82 1.84e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
3.45 1.87e-02 GO:0031098 stress-activated protein kinase signaling cascade
2.13 2.03e-02 GO:0032583 regulation of gene-specific transcription
3.99 2.03e-02 GO:0034142 toll-like receptor 4 signaling pathway
1.45 2.24e-02 GO:0048523 negative regulation of cellular process
2.02 2.59e-02 GO:0043065 positive regulation of apoptosis
1.81 2.97e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.01 3.04e-02 GO:0043068 positive regulation of programmed cell death
1.91 3.53e-02 GO:0010629 negative regulation of gene expression
1.42 3.62e-02 GO:0048519 negative regulation of biological process
4.34 3.71e-02 GO:0061039 ovum-producing ovary development
1.28 3.72e-02 GO:0044260 cellular macromolecule metabolic process
2.07 3.80e-02 GO:0051094 positive regulation of developmental process
2.19 3.87e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.75 3.96e-02 GO:0031328 positive regulation of cellular biosynthetic process
2.22 3.96e-02 GO:0018193 peptidyl-amino acid modification
1.68 4.57e-02 GO:0032774 RNA biosynthetic process
1.97 4.59e-02 GO:0010942 positive regulation of cell death

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.34 9.73e-05 GO:0005886 plasma membrane
1.50 1.63e-04 GO:0044459 plasma membrane part
1.33 2.12e-04 GO:0071944 cell periphery
4.28 5.51e-04 GO:0033267 axon part
1.61 2.74e-03 GO:0005887 integral to plasma membrane
1.60 3.19e-03 GO:0031226 intrinsic to plasma membrane
1.06 4.56e-03 GO:0044464 cell part
1.06 4.65e-03 GO:0005623 cell
2.89 1.65e-02 GO:0034703 cation channel complex
1.96 4.32e-02 GO:0045202 synapse

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.07 9.57e-06 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.87 2.82e-05 GO:0001071 nucleic acid binding transcription factor activity
1.87 2.82e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.96 6.44e-05 GO:0016301 kinase activity
4.12 7.22e-05 GO:0005057 receptor signaling protein activity
3.27 1.65e-04 GO:0005085 guanyl-nucleotide exchange factor activity
1.58 2.69e-04 GO:0016740 transferase activity
1.98 1.03e-03 GO:0004672 protein kinase activity
1.74 2.88e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
4.87 5.91e-03 GO:0004702 receptor signaling protein serine/threonine kinase activity
1.10 1.35e-02 GO:0005488 binding
2.90 1.59e-02 GO:0022843 voltage-gated cation channel activity
1.95 2.46e-02 GO:0030695 GTPase regulator activity
2.21 3.25e-02 GO:0005083 small GTPase regulator activity
3.34 3.76e-02 GO:0005088 Ras guanyl-nucleotide exchange factor activity
3.48 4.32e-02 GO:0019199 transmembrane receptor protein kinase activity
1.60 4.35e-02 GO:0030528 transcription regulator activity
1.90 4.42e-02 GO:0060589 nucleoside-triphosphatase regulator activity