Motif ID: CEBPA,B_DDIT3.p2

Z-value: 1.001


Transcription factors associated with CEBPA,B_DDIT3.p2:

Gene SymbolEntrez IDGene Name
CEBPA 1050 CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB 1051 CCAAT/enhancer binding protein (C/EBP), beta
DDIT3 1649 DNA-damage-inducible transcript 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CEBPAchr19_-_337934410.371.2e-08Click!
DDIT3chr12_-_579142870.187.6e-03Click!
CEBPBchr20_+_488071190.171.1e-02Click!


Activity profile for motif CEBPA,B_DDIT3.p2.

activity profile for motif CEBPA,B_DDIT3.p2


Sorted Z-values histogram for motif CEBPA,B_DDIT3.p2

Sorted Z-values for motif CEBPA,B_DDIT3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CEBPA,B_DDIT3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_140013285 16.597 NM_001040021
NM_001174104
NM_001174105
CD14


CD14 molecule


chr5_-_140012730 16.479 CD14
CD14 molecule
chr3_+_186330859 16.077 AHSG
alpha-2-HS-glycoprotein
chr3_+_186330844 16.041 NM_001622
AHSG
alpha-2-HS-glycoprotein
chr3_+_186330711 13.985 AHSG
alpha-2-HS-glycoprotein
chr19_+_45452427 10.149 APOC2
apolipoprotein C-II
chr3_+_157154579 10.032 NM_002852
PTX3
pentraxin 3, long
chr2_-_216300770 9.897 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr17_-_64225496 9.490 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr5_-_140013034 8.478 NM_000591
CD14
CD14 molecule
chr9_+_117085302 7.549 NM_000607
ORM1
orosomucoid 1
chr16_+_56966025 7.324 HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr11_+_114167168 7.267 NNMT
nicotinamide N-methyltransferase
chrX_-_13835187 6.705 GPM6B
glycoprotein M6B
chr9_+_117092068 6.701 NM_000608
ORM2
orosomucoid 2
chr2_-_113594325 6.619 NM_000576
IL1B
interleukin 1, beta
chr11_-_33913835 6.492 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr11_+_114167197 6.041 NNMT
nicotinamide N-methyltransferase
chr17_-_34524054 6.011 NM_001001437
NM_021006
CCL3L3
CCL3
CCL3L1
chemokine (C-C motif) ligand 3-like 3
chemokine (C-C motif) ligand 3
chemokine (C-C motif) ligand 3-like 1
chr9_-_77502262 5.627 NM_001177311
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr12_-_122296619 5.382 NM_002150
HPD
4-hydroxyphenylpyruvate dioxygenase
chr16_-_70323343 5.246 AARS
alanyl-tRNA synthetase
chr16_-_70323407 5.153 NM_001605
AARS
alanyl-tRNA synthetase
chr9_-_77503009 5.051 NM_017662
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr1_+_111770280 4.966 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr7_-_56101830 4.956 PSPH
phosphoserine phosphatase
chr6_+_31895401 4.927 C2
complement component 2
chr19_-_44174497 4.753 NM_001005376
NM_001005377
NM_002659
PLAUR


plasminogen activator, urokinase receptor


chr8_-_17743062 4.743 FGL1
fibrinogen-like 1
chr2_-_63815581 4.722 WDPCP
WD repeat containing planar cell polarity effector
chr8_-_27115935 4.678 STMN4
stathmin-like 4
chr15_+_41245635 4.589 NM_001142776
NM_024111
CHAC1

ChaC, cation transport regulator homolog 1 (E. coli)

chr6_+_31895201 4.478 NM_000063
NM_001145903
C2

complement component 2

chrX_-_13835213 4.326 GPM6B
glycoprotein M6B
chr17_+_1665281 4.293 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr6_+_131894343 4.288 NM_000045
NM_001244438
ARG1

arginase, liver

chr16_+_75252882 4.141 NM_001906
CTRB1
chymotrypsinogen B1
chr12_-_113841654 4.086 NM_006843
SDS
serine dehydratase
chr4_-_10023094 3.900 NM_020041
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr4_-_71532341 3.899 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr16_+_24266873 3.876 NM_006539
CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr5_-_24645084 3.825 NM_006727
CDH10
cadherin 10, type 2 (T2-cadherin)
chr1_-_230513390 3.765 NM_024554
PGBD5
piggyBac transposable element derived 5
chr17_+_1665306 3.722 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr16_-_28550227 3.674 NUPR1
nuclear protein, transcriptional regulator, 1
chr9_+_125132823 3.560 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr9_-_123812535 3.507 NM_001735
C5
complement component 5
chr11_+_59824129 3.505 MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr14_-_60337350 3.489 NM_021136
RTN1
reticulon 1
chr2_+_128175989 3.405 NM_000312
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr9_+_80911990 3.382 NM_021154
NM_058179
PSAT1

phosphoserine aminotransferase 1

chr16_-_21663962 3.346 NM_005849
IGSF6
immunoglobulin superfamily, member 6
chr5_+_161275897 3.345 NM_001127646
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr17_+_1665342 3.274 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr12_-_121736110 3.269 NM_006549
NM_153499
NM_153500
NM_172214
NM_172215
NM_172216
CAMKK2





calcium/calmodulin-dependent protein kinase kinase 2, beta





chr8_-_110657745 3.259 NM_001099751
NM_001099752
SYBU

syntabulin (syntaxin-interacting)

chr6_+_32605182 3.196 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr22_+_23054862 3.122 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr8_+_24151579 3.115 NM_014265
NM_021777
ADAM28

ADAM metallopeptidase domain 28

chr8_-_27115897 3.115 NM_030795
STMN4
stathmin-like 4
chr11_-_102668892 2.992 NM_001145938
NM_002421
MMP1

matrix metallopeptidase 1 (interstitial collagenase)

chr6_+_31913852 2.976 CFB
complement factor B
chr16_-_28550324 2.965 NM_001042483
NM_012385
NUPR1

nuclear protein, transcriptional regulator, 1

chr19_+_47813074 2.946 NM_001736
C5AR1
complement component 5a receptor 1
chr8_+_22019167 2.926 NM_001172357
NM_001172410
NM_003018
SFTPC


surfactant protein C


chr4_+_157997181 2.891 NM_000824
NM_001166061
NM_001166060
GLRB


glycine receptor, beta


chr1_+_196621007 2.879 NM_000186
NM_001014975
CFH

complement factor H

chr14_+_21359542 2.875 NM_002935
RNASE3
ribonuclease, RNase A family, 3
chr2_-_74542149 2.840 NM_021196
SLC4A5
solute carrier family 4, sodium bicarbonate cotransporter, member 5
chr17_+_56315786 2.830 NM_001160102
NM_006151
LPO

lactoperoxidase

chr17_+_1665233 2.820 NM_002615
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr5_-_147211141 2.797 SPINK1
serine peptidase inhibitor, Kazal type 1
chr11_+_59824054 2.792 NM_001031666
NM_001031809
NM_006138
MS4A3


membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)


chr1_-_151345156 2.760 NM_003944
SELENBP1
selenium binding protein 1
chr14_+_21423627 2.756 NM_002934
RNASE2
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr9_-_77502635 2.667 NM_001177310
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr1_-_31345361 2.558 SDC3
syndecan 3
chr8_-_110661007 2.558 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chrX_+_144908927 2.393 NM_004709
CXorf1
chromosome X open reading frame 1
chr17_-_55980749 2.329 NM_017949
CUEDC1
CUE domain containing 1
chr3_-_46505077 2.328 NM_001199149
LTF
lactotransferrin
chr16_+_27438578 2.289 NM_021798
IL21R
interleukin 21 receptor
chr11_+_71846755 2.226 NM_000804
FOLR3
folate receptor 3 (gamma)
chr6_-_11779279 2.209 NM_001143948
NM_032744
C6orf105

chromosome 6 open reading frame 105

chr12_+_5153084 2.198 NM_002234
KCNA5
potassium voltage-gated channel, shaker-related subfamily, member 5
chr6_-_41254392 2.177 NM_001242589
NM_001242590
NM_018643
TREM1


triggering receptor expressed on myeloid cells 1


chr5_-_66492574 2.155 NM_005582
CD180
CD180 molecule
chr19_+_11350282 2.089 NM_018687
C19orf80
chromosome 19 open reading frame 80
chr19_+_41497182 2.080 NM_000767
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chrX_-_13835012 2.037 GPM6B
glycoprotein M6B
chr3_-_42305438 2.034 NM_001174138
CCK
cholecystokinin
chr1_-_173886401 2.019 SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr12_-_52867521 2.008 NM_173086
KRT6C
keratin 6C
chr4_+_113739203 1.983 NM_001127493
ANK2
ankyrin 2, neuronal
chr12_-_52845862 1.926 NM_005555
KRT6B
keratin 6B
chr19_+_41430123 1.911 CYP2B7P1
cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
chr17_-_34625628 1.892 NM_001001437
NM_021006
CCL3L3
CCL3
CCL3L1
chemokine (C-C motif) ligand 3-like 3
chemokine (C-C motif) ligand 3
chemokine (C-C motif) ligand 3-like 1
chr7_-_64023444 1.864


chr7_-_37024664 1.860 NM_001039459
ELMO1
engulfment and cell motility 1
chr17_-_15523017 1.852 NM_006382
CDRT1
CMT1A duplicated region transcript 1
chr7_-_83270746 1.836 NM_001178129
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr6_+_36644236 1.792 NM_001220777
NM_078467
CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

chr7_+_90339146 1.775 CDK14
cyclin-dependent kinase 14
chr12_-_25101993 1.769 BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr12_-_15114495 1.750 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr3_+_1134619 1.749 NM_014461
CNTN6
contactin 6
chrX_-_138724851 1.734 NM_001171877
NM_001171878
NM_001171879
NM_005369
MCF2



MCF.2 cell line derived transforming sequence



chr7_+_90338711 1.710 NM_012395
CDK14
cyclin-dependent kinase 14
chr1_+_153330329 1.692 NM_002965
S100A9
S100 calcium binding protein A9
chr12_-_25101923 1.691 BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr12_-_57914287 1.686 NM_001195053
NM_001195054
NM_001195055
NM_001195056
NM_001195057
NM_004083
DDIT3





DNA-damage-inducible transcript 3





chr11_-_66675334 1.686 NM_022172
PC
pyruvate carboxylase
chr11_+_18287807 1.652 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chr1_+_196857143 1.641 NM_001201550
NM_001201551
NM_006684
CFHR4


complement factor H-related 4


chr12_+_54426831 1.620 NM_018953
HOXC5
homeobox C5
chr3_+_186435097 1.600 NM_000893
NM_001102416
NM_001166451
KNG1


kininogen 1


chr8_+_42552561 1.595 NM_000749
CHRNB3
cholinergic receptor, nicotinic, beta 3
chr19_-_18197632 1.584 NM_005535
NM_153701
IL12RB1

interleukin 12 receptor, beta 1

chr16_-_21663908 1.583 IGSF6
immunoglobulin superfamily, member 6
chr12_-_10151689 1.575 NM_001099431
NM_016509
CLEC1B

C-type lectin domain family 1, member B

chr17_+_73996986 1.565 NM_001258
CDK3
cyclin-dependent kinase 3
chr3_+_149192479 1.554 TM4SF4
transmembrane 4 L six family member 4
chrX_-_13835313 1.547 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr18_+_61637262 1.501 NM_001031848
NM_002640
NM_198833
SERPINB8


serpin peptidase inhibitor, clade B (ovalbumin), member 8


chr1_-_20250051 1.496 NM_014589
PLA2G2E
phospholipase A2, group IIE
chr14_-_70263871 1.478 NM_003049
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr9_-_125675571 1.433 NM_006626
ZBTB6
zinc finger and BTB domain containing 6
chr19_+_1450208 1.379 APC2
adenomatosis polyposis coli 2
chr11_-_102668822 1.308 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr19_+_49078992 1.299 NM_004605
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
chr4_-_71532206 1.296 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr5_-_94224601 1.287 MCTP1
multiple C2 domains, transmembrane 1
chr2_+_113816684 1.283 NM_012275
IL36RN
interleukin 36 receptor antagonist
chr18_-_55289014 1.276 NARS
asparaginyl-tRNA synthetase
chr3_+_186739643 1.253 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr6_+_31913920 1.249 CFB
complement factor B
chr5_-_151066445 1.247 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr11_+_71927818 1.240 NM_000803
NM_001113534
NM_001113535
NM_001113536
FOLR2



folate receptor 2 (fetal)



chr5_-_176836488 1.229 F12
coagulation factor XII (Hageman factor)
chr12_-_25102281 1.228 NM_001178091
NM_001178092
NM_005504
BCAT1


branched chain amino-acid transaminase 1, cytosolic


chr4_+_159131400 1.206 NM_018342
TMEM144
transmembrane protein 144
chr11_+_60260250 1.196 NM_001164470
NM_017716
MS4A12

membrane-spanning 4-domains, subfamily A, member 12

chrX_-_101112548 1.187 NM_032946
NXF5
nuclear RNA export factor 5
chr1_-_9129666 1.165 NM_001135585
NM_003039
SLC2A5

solute carrier family 2 (facilitated glucose/fructose transporter), member 5

chr3_-_129599220 1.160 NM_001017395
TMCC1
transmembrane and coiled-coil domain family 1
chr3_+_46395574 1.147 CCR2
chemokine (C-C motif) receptor 2
chr4_-_15940362 1.137 NM_005130
FGFBP1
fibroblast growth factor binding protein 1
chr1_-_144997110 1.130 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr2_+_237478379 1.130 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr13_-_30169584 1.121 SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr1_+_161185061 1.120 FCER1G
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr12_+_21679190 1.106 NM_030572
C12orf39
chromosome 12 open reading frame 39
chr2_+_236402948 1.099 AGAP1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr16_+_3405888 1.086 NM_012368
OR2C1
olfactory receptor, family 2, subfamily C, member 1
chr15_+_58724174 1.069 NM_000236
LIPC
lipase, hepatic
chr5_+_140734767 1.069 NM_018917
NM_032053
PCDHGA4

protocadherin gamma subfamily A, 4

chr19_+_44084695 1.065 NM_001193622
LOC390940
uncharacterized protein ENSP00000244321
chr19_+_50015535 1.063 NM_001136019
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr19_-_47128293 1.054 NM_000960
PTGIR
prostaglandin I2 (prostacyclin) receptor (IP)
chr1_-_161207879 1.050 NM_001077469
NM_001077470
NM_001077471
NM_001077472
NM_001077473
NM_001077474
NM_001077475
NM_001077476
NM_001077477
NM_001077478
NM_001077479
NM_001077480
NM_001077481
NM_001077482
NM_005122
NR1I3














nuclear receptor subfamily 1, group I, member 3














chr21_+_43619798 1.030 NM_207627
NM_207628
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr4_-_70826712 1.017 NM_001891
CSN2
casein beta
chr12_-_16759531 1.009 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr19_-_48614013 0.997 NM_001159322
NM_001159323
NM_003706
PLA2G4C


phospholipase A2, group IVC (cytosolic, calcium-independent)


chr21_-_15918635 0.995 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr16_-_90076528 0.985 NM_024043
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr12_-_63328857 0.982 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr12_-_13103317 0.980 NM_018654
GPRC5D
G protein-coupled receptor, family C, group 5, member D
chr7_+_143657019 0.971 NM_012369
OR2F1
olfactory receptor, family 2, subfamily F, member 1
chr7_+_28338939 0.947 NM_182899
CREB5
cAMP responsive element binding protein 5
chr14_-_106494166 0.944 IGHV4-31
IGHA1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
chr3_+_46395224 0.936 NM_001123041
NM_001123396
CCR2

chemokine (C-C motif) receptor 2

chr18_-_55288951 0.934 NARS
asparaginyl-tRNA synthetase
chr16_+_19467771 0.933 NM_024780
TMC5
transmembrane channel-like 5
chrX_-_13956644 0.918 NM_001001994
GPM6B
glycoprotein M6B
chr6_-_157744536 0.917 TMEM242
transmembrane protein 242
chrX_+_46940235 0.917 RGN
regucalcin (senescence marker protein-30)
chr10_-_47173917 0.913 NM_001040084
NM_001098845
ANXA8L2
ANXA8
ANXA8L1
annexin A8-like 2
annexin A8
annexin A8-like 1
chr17_+_32683470 0.909 NM_005408
CCL13
chemokine (C-C motif) ligand 13
chr9_+_135937364 0.897 NM_001807
CEL
carboxyl ester lipase (bile salt-stimulated lipase)
chr6_+_131958441 0.868 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr4_-_176733413 0.868 GPM6A
glycoprotein M6A
chr5_+_125758818 0.866 NM_001146320
NM_001146321
NM_023927
GRAMD3


GRAM domain containing 3


chr11_+_22689653 0.861 NM_177553
GAS2
growth arrest-specific 2
chr7_-_97619350 0.850 NM_006188
OCM2
oncomodulin 2
chr5_-_151066492 0.850 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr3_+_32993065 0.848 NM_005508
CCR4
chemokine (C-C motif) receptor 4
chr14_-_89016806 0.833 PTPN21
protein tyrosine phosphatase, non-receptor type 21
chrX_-_40506666 0.826 CXorf38
chromosome X open reading frame 38
chr2_+_113816214 0.826 NM_173170
IL36RN
interleukin 36 receptor antagonist
chr7_-_44530178 0.826 NM_015332
NUDCD3
NudC domain containing 3
chr16_+_202853 0.817 NM_005332
HBZ
hemoglobin, zeta
chr16_-_84651519 0.802 COTL1
coactosin-like 1 (Dictyostelium)
chr19_+_6887576 0.797 NM_001974
EMR1
egf-like module containing, mucin-like, hormone receptor-like 1
chr2_-_211018294 0.790 C2orf67
chromosome 2 open reading frame 67
chr5_-_176836535 0.788 NM_000505
F12
coagulation factor XII (Hageman factor)
chr16_+_67381252 0.788 NM_001161575
LRRC36
leucine rich repeat containing 36
chr7_+_26400503 0.788 NM_001199837
SNX10
sorting nexin 10
chr12_-_49259549 0.786 NM_014470
RND1
Rho family GTPase 1
chr9_+_116342939 0.776 NM_021106
RGS3
regulator of G-protein signaling 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.87 2.16e-15 GO:0006955 immune response
1.61 1.39e-12 GO:0050896 response to stimulus
2.79 2.21e-11 GO:0002376 immune system process
3.06 5.56e-09 GO:0006952 defense response
2.03 3.71e-08 GO:0042221 response to chemical stimulus
4.25 3.51e-06 GO:0006954 inflammatory response
2.48 9.94e-06 GO:0009605 response to external stimulus
1.84 1.30e-05 GO:0006950 response to stress
2.49 4.32e-05 GO:0009611 response to wounding
4.32 5.83e-05 GO:0032101 regulation of response to external stimulus
1.83 1.69e-04 GO:0065008 regulation of biological quality
2.15 1.71e-04 GO:0010033 response to organic substance
1.52 3.80e-04 GO:0051716 cellular response to stimulus
1.59 4.02e-04 GO:0007165 signal transduction
3.29 4.55e-04 GO:0045087 innate immune response
7.71 7.70e-04 GO:0072376 protein activation cascade
4.15 1.09e-03 GO:0072507 divalent inorganic cation homeostasis
3.59 1.15e-03 GO:0055065 metal ion homeostasis
6.47 1.30e-03 GO:0006959 humoral immune response
3.87 1.42e-03 GO:0008202 steroid metabolic process
2.98 1.66e-03 GO:0006873 cellular ion homeostasis
2.86 2.18e-03 GO:0050801 ion homeostasis
3.54 2.78e-03 GO:0006875 cellular metal ion homeostasis
3.37 3.07e-03 GO:0030003 cellular cation homeostasis
2.88 3.12e-03 GO:0055082 cellular chemical homeostasis
4.05 3.14e-03 GO:0055074 calcium ion homeostasis
4.05 3.14e-03 GO:0072503 cellular divalent inorganic cation homeostasis
3.23 3.42e-03 GO:0055080 cation homeostasis
1.50 4.17e-03 GO:0023052 signaling
2.25 4.91e-03 GO:0040011 locomotion
4.71 5.42e-03 GO:0001819 positive regulation of cytokine production
3.13 5.67e-03 GO:0051240 positive regulation of multicellular organismal process
2.66 8.43e-03 GO:0009607 response to biotic stimulus
3.92 9.62e-03 GO:0006874 cellular calcium ion homeostasis
2.57 9.91e-03 GO:0019725 cellular homeostasis
4.14 1.03e-02 GO:0010876 lipid localization
2.44 1.23e-02 GO:0048878 chemical homeostasis
15.68 1.46e-02 GO:0010574 regulation of vascular endothelial growth factor production
1.26 1.66e-02 GO:0065007 biological regulation
6.05 2.25e-02 GO:0032102 negative regulation of response to external stimulus
3.03 2.54e-02 GO:0009991 response to extracellular stimulus
1.27 2.96e-02 GO:0050789 regulation of biological process
10.08 3.07e-02 GO:0030195 negative regulation of blood coagulation
5.80 3.18e-02 GO:0050671 positive regulation of lymphocyte proliferation
5.72 3.55e-02 GO:0032946 positive regulation of mononuclear cell proliferation
1.87 3.63e-02 GO:0051239 regulation of multicellular organismal process
9.73 3.80e-02 GO:0050819 negative regulation of coagulation
5.65 3.96e-02 GO:0070665 positive regulation of leukocyte proliferation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.37 3.35e-14 GO:0005576 extracellular region
3.10 2.84e-10 GO:0005615 extracellular space
2.68 3.47e-09 GO:0044421 extracellular region part
1.47 3.28e-04 GO:0005886 plasma membrane
1.46 3.99e-04 GO:0071944 cell periphery
2.21 1.03e-03 GO:0005626 insoluble fraction
2.22 1.25e-03 GO:0005624 membrane fraction
8.23 3.58e-03 GO:0043679 axon terminus
1.95 3.60e-03 GO:0000267 cell fraction
7.84 4.99e-03 GO:0044306 neuron projection terminus
1.83 1.10e-02 GO:0005887 integral to plasma membrane
1.80 1.71e-02 GO:0031226 intrinsic to plasma membrane
9.80 2.46e-02 GO:0043195 terminal button
1.55 2.97e-02 GO:0044459 plasma membrane part
4.95 3.91e-02 GO:0033267 axon part

Gene overrepresentation in function category:

enrichment   p-value GO term description
9.41 5.08e-04 GO:0003823 antigen binding
1.79 1.74e-03 GO:0004872 receptor activity
1.66 4.94e-03 GO:0004871 signal transducer activity
1.66 4.94e-03 GO:0060089 molecular transducer activity
3.85 1.10e-02 GO:0001871 pattern binding
3.85 1.10e-02 GO:0030247 polysaccharide binding
3.40 3.94e-02 GO:0005126 cytokine receptor binding
4.24 3.95e-02 GO:0008201 heparin binding