Motif ID: ETS1,2.p2

Z-value: 2.348


Transcription factors associated with ETS1,2.p2:

Gene SymbolEntrez IDGene Name
ETS1 2113 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
ETS2 2114 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ETS1chr11_-_1284574520.505.0e-15Click!
ETS2chr21_+_401778470.235.4e-04Click!


Activity profile for motif ETS1,2.p2.

activity profile for motif ETS1,2.p2


Sorted Z-values histogram for motif ETS1,2.p2

Sorted Z-values for motif ETS1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ETS1,2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr21_-_46340874 52.542 NM_000211
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr21_-_46340821 50.174 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr19_+_49838734 45.781 CD37
CD37 molecule
chr13_+_31287614 45.453 NM_001204406
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr19_+_49838700 45.450 CD37
CD37 molecule
chr9_-_137809710 42.810 NM_002003
FCN1
ficolin (collagen/fibrinogen domain containing) 1
chr1_-_31230594 41.733 LAPTM5
lysosomal protein transmembrane 5
chr13_-_46756295 41.515 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr21_-_46340776 40.057 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_-_31230673 37.987 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr19_+_49838673 37.972 NM_001040031
NM_001774
CD37

CD37 molecule

chr6_+_31553955 36.079 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr8_+_38034066 35.913 NM_001204878
NM_004874
BAG4

BCL2-associated athanogene 4

chr19_+_49838646 35.843 CD37
CD37 molecule
chr22_-_17680485 34.682 NM_177405
CECR1
cat eye syndrome chromosome region, candidate 1
chr9_-_88969323 33.823 NM_001185059
NM_001185074
NM_024617
ZCCHC6


zinc finger, CCHC domain containing 6


chr16_+_30194925 33.303 CORO1A
coronin, actin binding protein, 1A
chr5_-_149792276 32.319 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr12_-_6798419 31.792 ZNF384
zinc finger protein 384
chr19_+_42387249 31.566 NM_004706
NM_198977
ARHGEF1

Rho guanine nucleotide exchange factor (GEF) 1

chr1_+_111415721 31.438 NM_000560
CD53
CD53 molecule
chr11_+_46722564 31.021 NM_001184751
ZNF408
zinc finger protein 408
chr11_-_46722139 30.596 ARHGAP1
Rho GTPase activating protein 1
chr11_-_46722160 30.455 ARHGAP1
Rho GTPase activating protein 1
chr8_-_38034168 29.891 LSM1
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr14_-_94856926 29.886 NM_001002235
NM_001002236
NM_001127700
NM_001127701
NM_001127702
NM_001127703
NM_001127704
NM_001127705
NM_001127706
NM_001127707
SERPINA1









serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1









chr19_+_16435734 29.363 KLF2
Kruppel-like factor 2 (lung)
chr1_+_111415791 29.085 CD53
CD53 molecule
chr13_-_46756326 28.554 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr19_+_47759802 28.298 CCDC9
coiled-coil domain containing 9
chr19_+_47759730 27.621 NM_015603
CCDC9
coiled-coil domain containing 9
chr11_+_46722316 27.494 NM_024741
ZNF408
zinc finger protein 408
chr19_+_42387307 26.457 ARHGEF1
Rho guanine nucleotide exchange factor (GEF) 1
chr22_+_37257004 26.297 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr1_-_183559669 25.651 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr12_+_7055736 24.798 NM_080548
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chrY_+_2709596 24.763 NM_001008
RPS4Y1
ribosomal protein S4, Y-linked 1
chr10_-_72362513 24.674 NM_001083116
NM_005041
PRF1

perforin 1 (pore forming protein)

chr10_-_72362441 24.336 PRF1
perforin 1 (pore forming protein)
chrY_+_2709630 24.223 RPS4Y1
ribosomal protein S4, Y-linked 1
chr14_+_21249209 24.173 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chr16_+_31085722 24.106 NM_014699
ZNF646
zinc finger protein 646
chr12_-_6798528 23.980 NM_133476
ZNF384
zinc finger protein 384
chr12_+_7055753 23.840 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr18_-_72264808 23.788 LOC400657
uncharacterized LOC400657
chr1_+_153330329 23.646 NM_002965
S100A9
S100 calcium binding protein A9
chr19_+_3178735 23.526 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chrX_-_107019001 23.502 NM_198057
TSC22D3
TSC22 domain family, member 3
chr8_+_38034296 23.449 BAG4
BCL2-associated athanogene 4
chr1_-_161520412 23.174 NM_001127593
NM_001127595
NM_001127596
FCGR3A


Fc fragment of IgG, low affinity IIIa, receptor (CD16a)


chr12_-_6798619 23.095 NM_001039920
NM_001135734
ZNF384

zinc finger protein 384

chr14_-_23284617 22.762 SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr19_-_37701385 22.514 NM_152279
ZNF585B
zinc finger protein 585B
chr16_+_30483959 22.237 NM_001114380
NM_002209
ITGAL

integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)

chr8_+_56792345 22.071 NM_001111097
NM_002350
LYN

v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

chr8_+_56792392 21.766 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr17_-_79269082 21.690 NM_001037984
NM_138570
SLC38A10

solute carrier family 38, member 10

chr1_-_183559463 21.485 NCF2
neutrophil cytosolic factor 2
chr16_+_31085751 21.330 ZNF646
zinc finger protein 646
chr16_+_30484049 21.313 ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr5_-_149380121 21.239 NM_001243253
LOC728287
TIGD6
uncharacterized LOC728287
tigger transposable element derived 6
chr12_+_69742130 20.968 NM_000239
LYZ
lysozyme
chr7_-_5569200 20.929 ACTB
actin, beta
chr1_-_183560010 20.528 NM_001127651
NCF2
neutrophil cytosolic factor 2
chr19_-_56632644 20.188 NM_001002836
ZNF787
zinc finger protein 787
chr19_-_10450262 20.123 NM_002162
ICAM3
intercellular adhesion molecule 3
chr12_+_69742140 19.463 LYZ
lysozyme
chr5_-_130970851 19.296 RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6
chr16_-_31085503 19.242 NM_024706
ZNF668
zinc finger protein 668
chr1_-_27952591 19.135 NM_001042747
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr3_-_121379757 19.116 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr18_-_72265038 18.952 LOC400657
uncharacterized LOC400657
chr8_+_56792399 18.871 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr1_-_52831817 18.846 NM_032449
CC2D1B
coiled-coil and C2 domain containing 1B
chr2_+_69001932 18.553 NM_001166276
NM_014882
ARHGAP25

Rho GTPase activating protein 25

chr5_-_149792370 18.407 NM_001025158
NM_001025159
NM_004355
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr4_+_2813966 18.373 SH3BP2
SH3-domain binding protein 2
chrX_+_128913881 18.179 NM_018990
SASH3
SAM and SH3 domain containing 3
chr22_+_37678565 17.744 CYTH4
cytohesin 4
chr16_+_29674564 17.694 SPN
sialophorin
chr14_+_105953531 17.690 CRIP1
cysteine-rich protein 1 (intestinal)
chrX_+_128913897 17.611 SASH3
SAM and SH3 domain containing 3
chr11_+_61197574 17.486 NM_017841
SDHAF2
succinate dehydrogenase complex assembly factor 2
chr15_-_40599872 17.429 PLCB2
phospholipase C, beta 2
chr22_-_31688329 17.414 NM_001135911
NM_052880
PIK3IP1

phosphoinositide-3-kinase interacting protein 1

chr16_-_31214054 17.373 NM_013258
NM_145182
PYCARD

PYD and CARD domain containing

chr19_+_39899749 17.337


chr3_-_121379701 17.079 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr10_-_88717319 16.929 NM_024756
MMRN2
multimerin 2
chr1_+_26644458 16.570 CD52
CD52 molecule
chr2_-_69870837 16.460 AAK1
AP2 associated kinase 1
chr1_-_161519817 16.417 NM_000569
NM_001127592
FCGR3A

Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

chr1_-_161601752 16.214 NM_000570
FCGR3B
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr19_-_36505102 16.090 ALKBH6
alkB, alkylation repair homolog 6 (E. coli)
chr15_+_91427664 16.041 NM_001143785
NM_002005
FES

feline sarcoma oncogene

chr19_+_57752051 15.883 NM_001023563
NM_001145078
ZNF805

zinc finger protein 805

chr13_-_46756291 15.881 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr15_-_40600118 15.308 NM_004573
PLCB2
phospholipase C, beta 2
chr21_-_15918635 15.236 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr6_-_109776942 15.185 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chrX_-_107018889 15.177 TSC22D3
TSC22 domain family, member 3
chr11_-_64512925 15.159 NM_153819
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr2_+_85804613 15.087 NM_003761
VAMP8
vesicle-associated membrane protein 8 (endobrevin)
chr10_+_26727692 15.059 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr13_-_44453825 15.012 NM_144974
CCDC122
coiled-coil domain containing 122
chr2_+_113931549 14.986 NM_012455
PSD4
pleckstrin and Sec7 domain containing 4
chr22_-_21213069 14.970 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr19_+_48248798 14.947 GLTSCR2
glioma tumor suppressor candidate region gene 2
chr22_+_17565844 14.946 NM_014339
IL17RA
interleukin 17 receptor A
chr1_-_1590403 14.938 CDK11A
CDK11B
cyclin-dependent kinase 11A
cyclin-dependent kinase 11B
chr22_+_37678423 14.922 NM_013385
CYTH4
cytohesin 4
chrX_-_47489703 14.814 NM_002621
CFP
complement factor properdin
chr14_-_24711767 14.779 NM_001099274
NM_012461
TINF2

TERF1 (TRF1)-interacting nuclear factor 2

chr6_-_109776946 14.766 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr5_-_130970907 14.680 NM_001164386
NM_001164387
NM_001164388
NM_001164389
NM_001164390
NM_016340
RAPGEF6





Rap guanine nucleotide exchange factor (GEF) 6





chr19_+_48248792 14.488 NM_015710
GLTSCR2
glioma tumor suppressor candidate region gene 2
chr19_-_36399120 14.422 TYROBP
TYRO protein tyrosine kinase binding protein
chr6_-_33267128 14.401 NM_001243738
NM_004761
RGL2

ral guanine nucleotide dissociation stimulator-like 2

chr18_+_11851388 14.148 NM_020412
CHMP1B
charged multivesicular body protein 1B
chr6_+_31554975 14.107 NM_001166538
NM_007161
NM_205840
LST1


leukocyte specific transcript 1


chr2_+_113931565 14.057 PSD4
pleckstrin and Sec7 domain containing 4
chr2_-_69870705 14.046 AAK1
AP2 associated kinase 1
chr21_-_44299605 13.986 WDR4
WD repeat domain 4
chr12_-_6233684 13.953 NM_000552
VWF
von Willebrand factor
chr1_+_150266261 13.929 NM_018997
NM_031901
MRPS21

mitochondrial ribosomal protein S21

chr22_-_37545944 13.894 NM_000878
IL2RB
interleukin 2 receptor, beta
chr10_+_26727651 13.887 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr13_+_31191829 13.869 NM_005800
USPL1
ubiquitin specific peptidase like 1
chr14_-_24036532 13.848 AP1G2
adaptor-related protein complex 1, gamma 2 subunit
chr12_-_51717835 13.768 BIN2
bridging integrator 2
chr9_+_77703412 13.721 OSTF1
osteoclast stimulating factor 1
chr19_+_16999871 13.661 F2RL3
coagulation factor II (thrombin) receptor-like 3
chr7_-_102105161 13.616 ALKBH4
alkB, alkylation repair homolog 4 (E. coli)
chr6_-_133084585 13.525 NM_078488
VNN2
vanin 2
chr12_+_54892567 13.518 NM_001184976
NCKAP1L
NCK-associated protein 1-like
chr3_+_47324329 13.501 NM_025010
KLHL18
kelch-like 18 (Drosophila)
chr15_+_81589240 13.452 NM_004513
IL16
interleukin 16
chr12_+_7060433 13.376 NM_002831
NM_080549
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr2_+_68961912 13.372 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr14_+_69865380 13.328 NM_001252148
NM_001252150
NM_018375
SLC39A9


solute carrier family 39 (zinc transporter), member 9


chr15_-_40600025 13.276 PLCB2
phospholipase C, beta 2
chr7_+_108210188 13.197 NM_012328
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr2_+_103035148 13.190 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr7_+_108210291 13.185 DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr20_-_23066828 13.150 NM_012072
CD93
CD93 molecule
chr14_-_23284565 13.135 SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr7_+_150264457 13.116 NM_018326
GIMAP4
GTPase, IMAP family member 4
chr11_-_67771527 13.095 NM_030930
UNC93B1
unc-93 homolog B1 (C. elegans)
chr6_-_109777171 13.048 NM_001159291
NM_022765
MICAL1

microtubule associated monoxygenase, calponin and LIM domain containing 1

chr14_+_69865095 12.984 NM_001252151
NM_001252152
SLC39A9

solute carrier family 39 (zinc transporter), member 9

chr12_-_51717905 12.874 NM_016293
BIN2
bridging integrator 2
chr7_+_150434435 12.742 NM_018384
GIMAP5
GTPase, IMAP family member 5
chr6_+_31554475 12.730 NM_205837
LST1
leukocyte specific transcript 1
chr16_+_29465821 12.641 NM_001014999
NM_001015000
NM_024044
NM_178044
SLX1A-SULT1A3
SLX1A

SLX1B

SLX1A-SULT1A3 readthrough
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)

SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)

chr20_+_42839599 12.640 LOC100505783
uncharacterized LOC100505783
chr12_-_15114495 12.609 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr2_-_96811138 12.609 NM_004418
DUSP2
dual specificity phosphatase 2
chr2_+_17935124 12.593 NM_182625
GEN1
Gen endonuclease homolog 1 (Drosophila)
chr1_+_24882565 12.542 NM_001010980
C1orf130
chromosome 1 open reading frame 130
chr22_-_37640287 12.536 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr19_+_16296211 12.529 NM_014077
FAM32A
family with sequence similarity 32, member A
chr11_+_5710816 12.507 NM_001199573
NM_006074
TRIM22

tripartite motif containing 22

chr2_+_17935379 12.475 NM_001130009
GEN1
Gen endonuclease homolog 1 (Drosophila)
chrX_+_48542159 12.461 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr14_+_75745480 12.396 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr6_-_32095993 12.389 NM_001136153
NM_004381
ATF6B

activating transcription factor 6 beta

chrX_+_67913490 12.323 STARD8
StAR-related lipid transfer (START) domain containing 8
chr2_+_143886898 12.290 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chrX_+_67913479 12.286 NM_001142504
STARD8
StAR-related lipid transfer (START) domain containing 8
chr22_+_37678519 12.265 CYTH4
cytohesin 4
chr1_+_10003485 12.221 NM_022787
NMNAT1
nicotinamide nucleotide adenylyltransferase 1
chr15_+_75074417 12.141 NM_001127190
NM_004383
CSK

c-src tyrosine kinase

chr1_+_28995214 12.137 NM_006582
NM_024482
GMEB1

glucocorticoid modulatory element binding protein 1

chr19_-_5680910 12.132 NM_205767
C19orf70
chromosome 19 open reading frame 70
chr19_-_13213973 12.131 NM_005583
LYL1
lymphoblastic leukemia derived sequence 1
chr16_+_69166538 12.120 CIRH1A
cirrhosis, autosomal recessive 1A (cirhin)
chr12_+_6898705 12.096 CD4
CD4 molecule
chr12_+_51318515 12.049 NM_014033
METTL7A
methyltransferase like 7A
chr5_+_156693051 12.042 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr6_-_170102098 11.921 NM_001202550
NM_182552
WDR27

WD repeat domain 27

chr1_+_158801105 11.888 NM_002432
MNDA
myeloid cell nuclear differentiation antigen
chr16_-_30366681 11.803 NM_006110
CD2BP2
CD2 (cytoplasmic tail) binding protein 2
chr16_+_28505920 11.797 NM_018690
APOBR
apolipoprotein B receptor
chr5_+_118604417 11.793 NM_001077654
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr11_+_117857123 11.781 IL10RA
interleukin 10 receptor, alpha
chr11_+_65190272 11.772


chr12_-_51717941 11.735 BIN2
bridging integrator 2
chr22_-_21213099 11.721 NM_058004
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr6_-_32497925 11.650 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr6_+_110012423 11.560 NM_014845
FIG4
FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
chr12_+_112856701 11.490 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr2_+_143886969 11.477 ARHGAP15
Rho GTPase activating protein 15
chr22_+_22786283 11.472


chr1_+_26644380 11.374 NM_001803
CD52
CD52 molecule
chr19_+_58694444 11.372 ZNF274
zinc finger protein 274
chr6_-_32095974 11.354 ATF6B
activating transcription factor 6 beta
chr19_+_56186426 11.342 NM_001130072
NM_013333
EPN1

epsin 1

chr1_-_161519526 11.331 FCGR3A
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr15_-_64648359 11.325 NM_022048
CSNK1G1
casein kinase 1, gamma 1
chr12_-_92539614 11.235 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.15 1.72e-21 GO:0009987 cellular process
1.22 1.20e-20 GO:0065007 biological regulation
1.74 2.92e-19 GO:0002376 immune system process
1.23 5.08e-17 GO:0050794 regulation of cellular process
1.21 1.13e-16 GO:0050789 regulation of biological process
1.52 1.56e-15 GO:0048583 regulation of response to stimulus
1.86 8.98e-15 GO:0006955 immune response
1.86 9.29e-14 GO:0002682 regulation of immune system process
1.34 5.93e-13 GO:0007165 signal transduction
1.30 1.55e-11 GO:0023052 signaling
1.27 8.94e-11 GO:0051716 cellular response to stimulus
1.96 4.24e-10 GO:0002684 positive regulation of immune system process
1.94 8.88e-10 GO:0050776 regulation of immune response
1.23 1.13e-09 GO:0043170 macromolecule metabolic process
1.36 1.41e-09 GO:0006950 response to stress
1.87 1.93e-09 GO:0001775 cell activation
1.66 3.99e-09 GO:0006952 defense response
1.18 1.46e-08 GO:0050896 response to stimulus
1.46 4.59e-08 GO:0009966 regulation of signal transduction
1.23 7.21e-08 GO:0044260 cellular macromolecule metabolic process
1.24 1.41e-07 GO:0019222 regulation of metabolic process
1.44 8.40e-07 GO:0035556 intracellular signal transduction
1.52 1.31e-06 GO:0032774 RNA biosynthetic process
1.24 1.63e-06 GO:0031323 regulation of cellular metabolic process
1.36 2.47e-06 GO:0006464 protein modification process
1.53 3.38e-06 GO:0009611 response to wounding
2.12 3.73e-06 GO:0051249 regulation of lymphocyte activation
1.28 3.91e-06 GO:0048518 positive regulation of biological process
2.03 6.38e-06 GO:0050865 regulation of cell activation
2.05 6.71e-06 GO:0002694 regulation of leukocyte activation
1.37 1.29e-05 GO:0023051 regulation of signaling
1.92 1.89e-05 GO:0050778 positive regulation of immune response
1.33 1.94e-05 GO:0043412 macromolecule modification
2.03 2.22e-05 GO:0030168 platelet activation
1.15 2.83e-05 GO:0044238 primary metabolic process
1.23 2.87e-05 GO:0080090 regulation of primary metabolic process
2.03 3.50e-05 GO:0002253 activation of immune response
1.50 4.26e-05 GO:0006351 transcription, DNA-dependent
1.33 5.78e-05 GO:0007166 cell surface receptor linked signaling pathway
1.67 6.10e-05 GO:0007596 blood coagulation
1.67 6.10e-05 GO:0050817 coagulation
1.26 6.12e-05 GO:0031326 regulation of cellular biosynthetic process
2.13 6.79e-05 GO:0002764 immune response-regulating signaling pathway
1.77 7.26e-05 GO:0051056 regulation of small GTPase mediated signal transduction
2.14 7.59e-05 GO:0002757 immune response-activating signal transduction
1.66 8.97e-05 GO:0007599 hemostasis
1.26 9.77e-05 GO:0009889 regulation of biosynthetic process
1.22 1.08e-04 GO:0016043 cellular component organization
1.22 1.34e-04 GO:0060255 regulation of macromolecule metabolic process
1.59 1.43e-04 GO:0042060 wound healing
1.47 1.50e-04 GO:0051704 multi-organism process
1.94 1.52e-04 GO:0045321 leukocyte activation
1.25 1.65e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.54 1.86e-04 GO:0050851 antigen receptor-mediated signaling pathway
1.13 1.93e-04 GO:0008152 metabolic process
1.23 2.95e-04 GO:0019538 protein metabolic process
2.10 3.22e-04 GO:0051251 positive regulation of lymphocyte activation
1.14 3.24e-04 GO:0044237 cellular metabolic process
1.48 3.48e-04 GO:0048584 positive regulation of response to stimulus
1.26 3.65e-04 GO:0010556 regulation of macromolecule biosynthetic process
2.04 4.21e-04 GO:0050867 positive regulation of cell activation
2.08 4.95e-04 GO:0050863 regulation of T cell activation
1.24 5.62e-04 GO:0051171 regulation of nitrogen compound metabolic process
2.38 5.69e-04 GO:0002768 immune response-regulating cell surface receptor signaling pathway
1.27 5.77e-04 GO:0006355 regulation of transcription, DNA-dependent
2.04 5.85e-04 GO:0002696 positive regulation of leukocyte activation
2.41 6.00e-04 GO:0002429 immune response-activating cell surface receptor signaling pathway
1.25 9.37e-04 GO:0044267 cellular protein metabolic process
1.25 1.14e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.20 1.38e-03 GO:0071840 cellular component organization or biogenesis
1.48 1.51e-03 GO:0006468 protein phosphorylation
1.29 1.64e-03 GO:0010467 gene expression
1.26 1.82e-03 GO:0051252 regulation of RNA metabolic process
1.55 1.99e-03 GO:0050878 regulation of body fluid levels
1.24 2.20e-03 GO:0048522 positive regulation of cellular process
2.12 3.38e-03 GO:0050870 positive regulation of T cell activation
1.56 3.40e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.39 3.73e-03 GO:0006793 phosphorus metabolic process
1.39 3.73e-03 GO:0006796 phosphate metabolic process
1.23 4.27e-03 GO:0010468 regulation of gene expression
1.45 5.79e-03 GO:0016192 vesicle-mediated transport
1.54 9.19e-03 GO:0080134 regulation of response to stress
1.28 9.39e-03 GO:0016070 RNA metabolic process
1.73 1.02e-02 GO:0006954 inflammatory response
1.57 1.39e-02 GO:0016044 cellular membrane organization
1.46 1.59e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.61 1.62e-02 GO:0007264 small GTPase mediated signal transduction
1.61 1.62e-02 GO:0010627 regulation of intracellular protein kinase cascade
1.56 1.72e-02 GO:0061024 membrane organization
1.62 1.80e-02 GO:0045087 innate immune response
1.86 1.80e-02 GO:0046649 lymphocyte activation
2.40 2.18e-02 GO:0007015 actin filament organization
1.40 2.35e-02 GO:0016310 phosphorylation
1.74 3.00e-02 GO:0030036 actin cytoskeleton organization
1.51 3.03e-02 GO:0009607 response to biotic stimulus
1.29 3.05e-02 GO:0065009 regulation of molecular function
1.39 3.98e-02 GO:0044093 positive regulation of molecular function
1.34 4.38e-02 GO:0042981 regulation of apoptosis
1.95 4.43e-02 GO:0002252 immune effector process
1.93 4.63e-02 GO:0002697 regulation of immune effector process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.08 8.29e-07 GO:0005622 intracellular
1.08 9.62e-07 GO:0044424 intracellular part
1.26 1.11e-04 GO:0044459 plasma membrane part
1.26 2.50e-04 GO:0005829 cytosol
1.59 5.30e-04 GO:0005768 endosome
3.11 3.26e-03 GO:0032587 ruffle membrane
1.12 4.15e-03 GO:0005634 nucleus
1.30 6.56e-03 GO:0005887 integral to plasma membrane
1.29 1.18e-02 GO:0031226 intrinsic to plasma membrane
2.43 1.24e-02 GO:0031256 leading edge membrane
1.03 1.57e-02 GO:0044464 cell part
1.03 1.63e-02 GO:0005623 cell
1.08 1.94e-02 GO:0005737 cytoplasm
1.08 2.13e-02 GO:0043227 membrane-bounded organelle
1.07 2.38e-02 GO:0043226 organelle
2.77 3.41e-02 GO:0030120 vesicle coat
1.07 3.83e-02 GO:0043229 intracellular organelle
1.07 4.09e-02 GO:0043231 intracellular membrane-bounded organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.20 1.96e-16 GO:0005515 protein binding
1.11 1.32e-14 GO:0005488 binding
3.55 2.53e-05 GO:0003823 antigen binding
1.60 4.10e-04 GO:0030695 GTPase regulator activity
1.59 4.77e-04 GO:0060589 nucleoside-triphosphatase regulator activity
2.00 1.35e-03 GO:0005085 guanyl-nucleotide exchange factor activity
2.23 3.63e-03 GO:0005057 receptor signaling protein activity
1.36 3.92e-03 GO:0001071 nucleic acid binding transcription factor activity
1.36 3.92e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
2.59 6.42e-03 GO:0035591 signaling adaptor activity
1.36 7.66e-03 GO:0030234 enzyme regulator activity
4.23 1.59e-02 GO:0019865 immunoglobulin binding
1.64 1.65e-02 GO:0005083 small GTPase regulator activity
1.20 3.47e-02 GO:0003677 DNA binding
1.49 4.10e-02 GO:0019904 protein domain specific binding
1.63 4.14e-02 GO:0032403 protein complex binding
1.37 4.63e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor