Motif ID: EVI1.p2

Z-value: 2.472


Transcription factors associated with EVI1.p2:

Gene SymbolEntrez IDGene Name
EVI1 2122 ecotropic viral integration site 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MECOMchr3_-_1693814170.581.2e-20Click!


Activity profile for motif EVI1.p2.

activity profile for motif EVI1.p2


Sorted Z-values histogram for motif EVI1.p2

Sorted Z-values for motif EVI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EVI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_88450243 91.312 SPARCL1
SPARC-like 1 (hevin)
chr9_+_139871954 68.202 NM_000954
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr8_-_27115897 62.831 NM_030795
STMN4
stathmin-like 4
chr17_+_53344966 50.667 HLF
hepatic leukemia factor
chr2_-_224467095 49.880 SCG2
secretogranin II
chr12_-_15038724 48.480 NM_000900
NM_001190839
MGP

matrix Gla protein

chr6_-_31514620 43.243 NM_001204078
NM_130463
NM_138282
ATP6V1G2


ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2


chr8_-_27115935 41.642 STMN4
stathmin-like 4
chr10_+_106034886 39.622 NM_001191014
NM_001191015
GSTO2

glutathione S-transferase omega 2

chr14_-_76447445 39.253 TGFB3
transforming growth factor, beta 3
chr19_-_36643770 38.626 NM_001864
COX7A1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr2_-_224467049 38.550 SCG2
secretogranin II
chr1_-_93399531 37.088


chr10_+_7745341 36.641 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr15_+_66874506 35.756


chr10_+_7745325 30.903 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr2_-_224467142 30.842 NM_003469
SCG2
secretogranin II
chr17_-_66951381 30.409 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr12_-_16758312 29.744 NM_001243611
LMO3
LIM domain only 3 (rhombotin-like 2)
chr6_+_31515391 28.886 NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr8_-_27941387 28.637 NM_001010906
C8orf80
chromosome 8 open reading frame 80
chr2_-_89165652 28.571


chr2_-_145274916 28.421 ZEB2
zinc finger E-box binding homeobox 2
chr12_-_16757944 28.195 LMO3
LIM domain only 3 (rhombotin-like 2)
chr8_+_80523376 27.948 STMN2
stathmin-like 2
chr5_+_140739589 27.204 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr6_-_22297729 27.162 NM_000948
PRL
prolactin
chr15_+_34261088 26.598 NM_012125
CHRM5
cholinergic receptor, muscarinic 5
chr12_+_20848288 26.107 NM_001145945
NM_001145946
NM_001145944
NM_017435
SLCO1C1



solute carrier organic anion transporter family, member 1C1



chr12_-_8218930 26.031 NM_004054
C3AR1
complement component 3a receptor 1
chr16_+_55542909 26.014 NM_017839
LPCAT2
lysophosphatidylcholine acyltransferase 2
chr12_-_8219001 25.900 C3AR1
complement component 3a receptor 1
chr10_+_7745284 25.774 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr11_+_92085261 25.523 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr10_-_88717319 25.318 NM_024756
MMRN2
multimerin 2
chr22_+_29138018 25.276 NM_172002
HSCB
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr6_-_116422408 25.274


chr6_+_31515352 25.269 NM_001144961
NM_005007
NFKBIL1

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1

chr4_+_106631966 24.912 NM_001031720
GSTCD
glutathione S-transferase, C-terminal domain containing
chr8_-_110655418 24.319 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr2_+_189839132 23.777 COL3A1
collagen, type III, alpha 1
chr12_-_371994 23.356 NM_001190997
NM_001243392
NM_016615
SLC6A13


solute carrier family 6 (neurotransmitter transporter, GABA), member 13


chrX_+_101502093 23.222 NM_022053
NM_001099686
NXF2
NXF2B
nuclear RNA export factor 2
nuclear RNA export factor 2B
chr10_+_7745354 22.927 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr14_+_95047758 22.747 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chrX_+_103031753 22.695 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr12_-_9268440 22.571 A2M
alpha-2-macroglobulin
chr5_+_55147206 22.450 NM_001242637
NM_001242638
NM_139017
IL31RA


interleukin 31 receptor A


chr5_+_175511848 21.957 NM_001079529
FAM153B
family with sequence similarity 153, member B
chrX_-_101694848 21.956 NM_022053
NM_001099686
NXF2
NXF2B
nuclear RNA export factor 2
nuclear RNA export factor 2B
chr19_-_20844312 21.405 NM_001076675
NM_145297
ZNF626

zinc finger protein 626

chr22_-_31688329 21.379 NM_001135911
NM_052880
PIK3IP1

phosphoinositide-3-kinase interacting protein 1

chr4_-_176923572 21.304 NM_005277
NM_201592
GPM6A

glycoprotein M6A

chr6_+_126240369 20.961 NM_001199622
NCOA7
nuclear receptor coactivator 7
chr1_-_182357871 20.703 GLUL
glutamate-ammonia ligase
chr6_+_52529157 20.691 LOC730101
uncharacterized LOC730101
chr3_-_145968819 20.525 PLSCR4
phospholipid scramblase 4
chr22_-_19512859 20.322 NM_001130861
NM_003277
CLDN5

claudin 5

chr3_-_145968958 20.277 NM_001128306
NM_001177304
NM_020353
PLSCR4


phospholipid scramblase 4


chr19_+_50031232 19.920 RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr6_+_29624757 19.843 NM_001008228
NM_001008229
NM_001170418
NM_002433
NM_206809
NM_206810
NM_206811
NM_206812
NM_206814
MOG








myelin oligodendrocyte glycoprotein








chr14_+_95047792 19.703 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr2_+_26403584 19.473 NM_001191033
FAM59B
family with sequence similarity 59, member B
chr1_+_104292439 19.453 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr19_-_21950322 19.127 NM_173531
ZNF100
zinc finger protein 100
chr20_-_44455932 19.006 NM_003279
TNNC2
troponin C type 2 (fast)
chr1_+_209859524 18.894 NM_001206741
NM_181755
HSD11B1

hydroxysteroid (11-beta) dehydrogenase 1

chr3_+_147127151 18.421 NM_003412
ZIC1
Zic family member 1
chr6_+_160327972 17.851 NM_002377
MAS1
MAS1 oncogene
chr9_-_107690435 17.835 ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chrX_+_103031433 17.428 NM_001128834
PLP1
proteolipid protein 1
chr12_+_85430098 17.416 NM_001079910
LRRIQ1
leucine-rich repeats and IQ motif containing 1
chr18_-_53303129 17.212 NM_001243226
TCF4
transcription factor 4
chr13_+_46626949 17.178 LOC100509894
uncharacterized LOC100509894
chrX_+_103031797 17.075 PLP1
proteolipid protein 1
chr13_+_49280619 17.006 NM_020377
CYSLTR2
cysteinyl leukotriene receptor 2
chr2_+_169929009 16.973 NM_001142270
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr7_-_8302141 16.744 NM_004968
ICA1
islet cell autoantigen 1, 69kDa
chrX_+_100805415 16.680 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr1_-_182357757 16.436 GLUL
glutamate-ammonia ligase
chr5_+_64920830 16.375 C5orf44
chromosome 5 open reading frame 44
chr2_+_166150340 16.124 NM_021007
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr9_+_40700290 16.016 NM_001083124
FAM75A3
family with sequence similarity 75, member A3
chr19_+_48964505 16.015 NM_170720
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr11_-_128894008 16.003 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr2_+_189839113 15.999 COL3A1
collagen, type III, alpha 1
chr4_-_76944585 15.982 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr22_+_36113917 15.852 NM_030642
APOL5
apolipoprotein L, 5
chr5_-_147162175 15.799 JAKMIP2
janus kinase and microtubule interacting protein 2
chr1_+_162602198 15.777 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chr10_+_7745229 15.744 NM_002216
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr19_+_22235278 15.646 ZNF257
zinc finger protein 257
chr1_+_1385068 15.510 NM_001039211
ATAD3C
ATPase family, AAA domain containing 3C
chr9_-_95244750 15.461 NM_001193335
NM_017680
ASPN

asporin

chr19_-_52133589 15.412 NM_003830
SIGLEC5
sialic acid binding Ig-like lectin 5
chr2_+_189839078 15.284 NM_000090
COL3A1
collagen, type III, alpha 1
chrX_+_2959511 14.963 NM_001201539
ARSF
arylsulfatase F
chr20_-_48099178 14.886 NM_004975
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr1_+_152881022 14.847 NM_005547
IVL
involucrin
chr5_+_140588267 14.774 NM_018932
PCDHB12
protocadherin beta 12
chr5_-_64920100 14.749 TRIM23
tripartite motif containing 23
chr19_+_6135650 14.703 NM_030924
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr1_-_161279724 14.688 NM_000530
MPZ
myelin protein zero
chr6_+_123100645 14.660 NM_001446
FABP7
fatty acid binding protein 7, brain
chr6_-_88854989 14.656 NM_033181
CNR1
cannabinoid receptor 1 (brain)
chr12_-_9268513 14.417 A2M
alpha-2-macroglobulin
chr7_-_15601574 14.364 NM_001004320
AGMO
alkylglycerol monooxygenase
chr3_-_58200397 14.315 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr8_+_22857413 14.149 RHOBTB2
Rho-related BTB domain containing 2
chr4_+_62362838 14.055 NM_015236
LPHN3
latrophilin 3
chr19_+_19976625 14.055 NM_021047
ZNF253
zinc finger protein 253
chr9_+_82187469 14.023 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr3_-_46608039 14.022 NM_024512
LRRC2
leucine rich repeat containing 2
chr1_+_162332772 13.850 NM_001126060
NOS1AP
nitric oxide synthase 1 (neuronal) adaptor protein
chr1_-_149889362 13.752 NM_014849
SV2A
synaptic vesicle glycoprotein 2A
chrY_-_27198250 13.749 NM_001002760
NM_001002761
NM_004678
BPY2B
BPY2C
BPY2
basic charge, Y-linked, 2B
basic charge, Y-linked, 2C
basic charge, Y-linked, 2
chr19_+_50030874 13.740 NM_020650
RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr1_+_50569581 13.738 NM_001144776
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr1_-_182922504 13.736 NM_030933
SHCBP1L
SHC SH2-domain binding protein 1-like
chr12_+_56732658 13.648 NM_016584
IL23A
interleukin 23, alpha subunit p19
chr17_+_41857802 13.610 NM_001136483
C17orf105
chromosome 17 open reading frame 105
chrY_+_26764150 13.598 NM_001002760
NM_001002761
NM_004678
BPY2B
BPY2C
BPY2
basic charge, Y-linked, 2B
basic charge, Y-linked, 2C
basic charge, Y-linked, 2
chrY_+_25130409 13.598 NM_001002760
NM_001002761
NM_004678
BPY2B
BPY2C
BPY2
basic charge, Y-linked, 2B
basic charge, Y-linked, 2C
basic charge, Y-linked, 2
chr19_-_38720312 13.528 NM_001135156
DPF1
D4, zinc and double PHD fingers family 1
chr1_+_162602308 13.517 DDR2
discoidin domain receptor tyrosine kinase 2
chr5_-_147162251 13.503 NM_014790
JAKMIP2
janus kinase and microtubule interacting protein 2
chr19_+_22235253 13.497 NM_033468
ZNF257
zinc finger protein 257
chr1_-_150587879 13.418


chr5_+_64920557 13.394 NM_001093755
NM_001093756
NM_001243737
NM_024941
C5orf44



chromosome 5 open reading frame 44



chr5_+_161112657 13.378 NM_000811
GABRA6
gamma-aminobutyric acid (GABA) A receptor, alpha 6
chr12_-_10251520 13.347 NM_016511
CLEC1A
C-type lectin domain family 1, member A
chrX_+_15525430 13.305 NM_001721
BMX
BMX non-receptor tyrosine kinase
chrX_-_43741593 13.277 NM_000898
MAOB
monoamine oxidase B
chr1_-_13390747 13.246 NM_001012276
PRAMEF8
PRAMEF7
PRAME family member 8
PRAME family member 7
chr14_+_95078713 13.228 NM_001085
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chrX_-_49965657 13.213 NM_003886
AKAP4
A kinase (PRKA) anchor protein 4
chr12_-_91576805 13.089 NM_001920
DCN
decorin
chr11_-_108368918 13.084 NM_153705
KDELC2
KDEL (Lys-Asp-Glu-Leu) containing 2
chr7_+_47694841 12.985 NM_001123065
C7orf65
chromosome 7 open reading frame 65
chr6_-_22303014 12.959 NM_001163558
PRL
prolactin
chr12_-_10151689 12.937 NM_001099431
NM_016509
CLEC1B

C-type lectin domain family 1, member B

chr4_+_55095263 12.823 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chrX_+_91090459 12.794 NM_001168360
NM_001168361
NM_001168362
NM_001168363
PCDH11X



protocadherin 11 X-linked



chr1_+_12976449 12.747 NM_001012276
PRAMEF8
PRAMEF7
PRAME family member 8
PRAME family member 7
chr14_-_94844881 12.619 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr1_-_146697155 12.614 NM_001144829
NM_001144830
NM_001461
FMO5


flavin containing monooxygenase 5


chr4_-_10041833 12.608 NM_001001290
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr12_+_72079873 12.535 NM_018279
TMEM19
transmembrane protein 19
chrX_-_65835845 12.488 NM_001242310
EDA2R
ectodysplasin A2 receptor
chr5_+_140165875 12.342 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chrX_-_78623006 12.332 NM_001171581
NM_004867
ITM2A

integral membrane protein 2A

chr1_+_170904611 12.316 NM_001163629
NM_025063
C1orf129

chromosome 1 open reading frame 129

chr3_+_133495925 12.206 TF
transferrin
chr7_+_142829169 12.084 NM_002652
PIP
prolactin-induced protein
chr21_-_39956823 12.083 NM_001243429
ERG
v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr9_+_82186846 12.069 NM_007005
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr8_-_6837568 12.043 NM_004084
NM_001042500
DEFA1
DEFA1B
defensin, alpha 1
defensin, alpha 1B
chr5_-_151066492 11.974 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chrX_-_62975005 11.970 NM_001173480
NM_015185
ARHGEF9

Cdc42 guanine nucleotide exchange factor (GEF) 9

chr6_+_153019029 11.948 NM_025107
MYCT1
myc target 1
chr4_-_176923480 11.902 GPM6A
glycoprotein M6A
chr14_-_81687265 11.867 NM_015859
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr1_-_168513201 11.840 NM_003175
XCL1
XCL2
chemokine (C motif) ligand 1
chemokine (C motif) ligand 2
chr8_-_6875777 11.685 NM_004084
NM_005217
NM_001042500
DEFA1
DEFA3
DEFA1B
defensin, alpha 1
defensin, alpha 3, neutrophil-specific
defensin, alpha 1B
chr16_-_21289571 11.682 CRYM
crystallin, mu
chr9_-_43630729 11.649 NM_001145196
FAM75A6
family with sequence similarity 75, member A6
chr1_+_104198301 11.591 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr9_+_134378335 11.518 POMT1
protein-O-mannosyltransferase 1
chr5_-_137475076 11.506 NM_003551
NME5
non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
chr8_-_38008332 11.492 NM_000349
STAR
steroidogenic acute regulatory protein
chr7_+_86273219 11.468 NM_000840
GRM3
glutamate receptor, metabotropic 3
chr12_-_9268475 11.465 A2M
alpha-2-macroglobulin
chr3_+_186330711 11.446 AHSG
alpha-2-HS-glycoprotein
chr5_-_41213513 11.435 NM_000065
C6
complement component 6
chrX_+_155227245 11.429 NM_002186
IL9R
interleukin 9 receptor
chr20_+_57875481 11.317 NM_000114
NM_207032
NM_207033
NM_207034
EDN3



endothelin 3



chr3_-_187454247 11.316 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr22_-_27014037 11.300 CRYBB1
crystallin, beta B1
chr1_+_205236591 11.194 TMCC2
transmembrane and coiled-coil domain family 2
chr8_+_133879202 11.171 NM_003235
TG
thyroglobulin
chr8_-_17767871 11.135


chr18_-_44561967 11.088 NM_016427
TCEB3B
transcription elongation factor B polypeptide 3B (elongin A2)
chr16_+_7382750 11.088 NM_145891
NM_145892
NM_145893
RBFOX1


RNA binding protein, fox-1 homolog (C. elegans) 1


chr5_-_75919051 11.047 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr5_-_64920149 11.028 NM_001656
NM_033227
NM_033228
TRIM23


tripartite motif containing 23


chr22_+_23213671 10.998 IGLV4-3
immunoglobulin lambda variable 4-3
chr21_-_42557165 10.983 NM_182832
PLAC4
placenta-specific 4
chr3_+_44916097 10.918 NM_003241
TGM4
transglutaminase 4 (prostate)
chr18_+_61582744 10.891 NM_005024
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr10_+_57358749 10.791 NM_001190478
MTRNR2L5
MT-RNR2-like 5
chr5_-_132161863 10.759 NM_133456
SHROOM1
shroom family member 1
chr19_-_51587466 10.677 NM_022046
KLK14
kallikrein-related peptidase 14
chr18_-_67624159 10.672 NM_006566
CD226
CD226 molecule
chrX_+_135730335 10.658 NM_000074
CD40LG
CD40 ligand
chrY_+_59330251 10.650 NM_002186
IL9R
interleukin 9 receptor
chr5_-_146460991 10.649 NM_181677
NM_181678
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr1_+_15802595 10.637 NM_015849
CELA2B
chymotrypsin-like elastase family, member 2B
chr16_-_21289637 10.578 CRYM
crystallin, mu
chr14_-_50862616 10.566 NM_004196
CDKL1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr5_+_156820161 10.514 CYFIP2
cytoplasmic FMR1 interacting protein 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.35 4.84e-09 GO:0032501 multicellular organismal process
2.06 1.63e-08 GO:0009611 response to wounding
1.43 4.11e-08 GO:0023052 signaling
2.53 7.42e-08 GO:0050776 regulation of immune response
2.18 8.96e-08 GO:0002682 regulation of immune system process
2.51 1.47e-07 GO:0002684 positive regulation of immune system process
1.66 2.14e-07 GO:0007166 cell surface receptor linked signaling pathway
2.03 4.76e-07 GO:0006952 defense response
1.42 2.12e-06 GO:0007165 signal transduction
3.25 3.16e-06 GO:0050867 positive regulation of cell activation
2.90 3.25e-06 GO:0050865 regulation of cell activation
2.94 3.66e-06 GO:0002694 regulation of leukocyte activation
1.96 6.68e-06 GO:0048584 positive regulation of response to stimulus
3.21 8.03e-06 GO:0002696 positive regulation of leukocyte activation
2.72 9.10e-06 GO:0006954 inflammatory response
2.67 1.59e-05 GO:0050778 positive regulation of immune response
1.73 1.68e-05 GO:0002376 immune system process
1.43 3.50e-05 GO:0048731 system development
1.24 6.67e-05 GO:0050896 response to stimulus
1.91 1.02e-04 GO:0007155 cell adhesion
1.91 1.02e-04 GO:0022610 biological adhesion
1.43 5.51e-04 GO:0006950 response to stress
1.30 6.49e-04 GO:0051716 cellular response to stimulus
1.84 8.12e-04 GO:0006955 immune response
1.33 9.43e-04 GO:0007275 multicellular organismal development
1.18 9.50e-04 GO:0065007 biological regulation
2.91 1.09e-03 GO:0051251 positive regulation of lymphocyte activation
2.64 1.37e-03 GO:0051249 regulation of lymphocyte activation
1.98 1.46e-03 GO:0007186 G-protein coupled receptor protein signaling pathway
3.00 1.54e-03 GO:0002697 regulation of immune effector process
1.35 1.66e-03 GO:0048856 anatomical structure development
4.99 2.21e-03 GO:0032649 regulation of interferon-gamma production
1.59 2.43e-03 GO:0051239 regulation of multicellular organismal process
2.57 2.58e-03 GO:0002253 activation of immune response
2.77 2.86e-03 GO:0003012 muscle system process
2.02 3.12e-03 GO:0009628 response to abiotic stimulus
1.42 3.70e-03 GO:0065008 regulation of biological quality
4.41 4.31e-03 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
1.78 4.37e-03 GO:0007267 cell-cell signaling
2.76 4.68e-03 GO:0050863 regulation of T cell activation
4.34 5.42e-03 GO:0002819 regulation of adaptive immune response
2.79 6.06e-03 GO:0006936 muscle contraction
2.28 6.73e-03 GO:0016337 cell-cell adhesion
1.29 6.84e-03 GO:0032502 developmental process
3.77 7.79e-03 GO:0002699 positive regulation of immune effector process
8.82 9.95e-03 GO:0046640 regulation of alpha-beta T cell proliferation
1.44 1.12e-02 GO:0048583 regulation of response to stimulus
2.84 1.14e-02 GO:0042445 hormone metabolic process
2.90 1.29e-02 GO:0050870 positive regulation of T cell activation
2.55 1.46e-02 GO:0010817 regulation of hormone levels
1.65 2.35e-02 GO:0006811 ion transport
5.88 2.39e-02 GO:0032729 positive regulation of interferon-gamma production
9.63 2.66e-02 GO:0045026 plasma membrane fusion
3.53 3.60e-02 GO:0034754 cellular hormone metabolic process
7.27 4.86e-02 GO:0032660 regulation of interleukin-17 production

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.79 7.59e-16 GO:0044459 plasma membrane part
2.00 1.42e-12 GO:0005887 integral to plasma membrane
1.73 1.85e-12 GO:0005576 extracellular region
1.46 2.02e-12 GO:0005886 plasma membrane
1.96 6.08e-12 GO:0031226 intrinsic to plasma membrane
1.44 8.78e-12 GO:0071944 cell periphery
2.13 1.18e-09 GO:0005615 extracellular space
1.93 5.90e-09 GO:0044421 extracellular region part
1.21 1.17e-06 GO:0016020 membrane
1.23 6.10e-06 GO:0044425 membrane part
1.24 6.03e-05 GO:0031224 intrinsic to membrane
1.24 9.17e-05 GO:0016021 integral to membrane
1.98 5.86e-03 GO:0009986 cell surface
1.50 2.00e-02 GO:0000267 cell fraction
1.68 3.24e-02 GO:0030054 cell junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.90 1.17e-03 GO:0004866 endopeptidase inhibitor activity
2.79 2.43e-03 GO:0061135 endopeptidase regulator activity
2.75 3.07e-03 GO:0030414 peptidase inhibitor activity
1.77 3.29e-03 GO:0005509 calcium ion binding
3.45 3.37e-03 GO:0004867 serine-type endopeptidase inhibitor activity
3.11 4.89e-03 GO:0019955 cytokine binding
2.46 7.11e-03 GO:0005125 cytokine activity
1.38 7.62e-03 GO:0004871 signal transducer activity
1.38 7.62e-03 GO:0060089 molecular transducer activity
1.51 1.24e-02 GO:0005215 transporter activity
2.45 1.53e-02 GO:0005126 cytokine receptor binding
1.55 1.85e-02 GO:0022892 substrate-specific transporter activity
1.57 1.96e-02 GO:0022857 transmembrane transporter activity
2.40 2.22e-02 GO:0061134 peptidase regulator activity
1.40 2.66e-02 GO:0004872 receptor activity