Motif ID: FEV.p2

Z-value: 1.782


Transcription factors associated with FEV.p2:

Gene SymbolEntrez IDGene Name
FEV 54738 FEV (ETS oncogene family)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FEVchr2_-_2198502730.484.3e-14Click!


Activity profile for motif FEV.p2.

activity profile for motif FEV.p2


Sorted Z-values histogram for motif FEV.p2

Sorted Z-values for motif FEV.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FEV.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_6798419 46.096 ZNF384
zinc finger protein 384
chr12_-_6798619 45.236 NM_001039920
NM_001135734
ZNF384

zinc finger protein 384

chr11_+_61129831 36.560 TMEM138
transmembrane protein 138
chr11_-_46722160 35.841 ARHGAP1
Rho GTPase activating protein 1
chr12_-_6798528 35.535 NM_133476
ZNF384
zinc finger protein 384
chr16_-_31085503 34.584 NM_024706
ZNF668
zinc finger protein 668
chr11_+_46722564 30.667 NM_001184751
ZNF408
zinc finger protein 408
chr16_+_31085722 29.201 NM_014699
ZNF646
zinc finger protein 646
chr11_+_61197574 28.782 NM_017841
SDHAF2
succinate dehydrogenase complex assembly factor 2
chr16_+_31085751 28.527 ZNF646
zinc finger protein 646
chr11_-_46722139 27.837 ARHGAP1
Rho GTPase activating protein 1
chr18_-_72264808 26.085 LOC400657
uncharacterized LOC400657
chr11_+_46722316 25.633 NM_024741
ZNF408
zinc finger protein 408
chr3_-_121379701 24.580 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_-_121379757 24.376 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr8_-_38034168 24.187 LSM1
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_+_17935379 23.695 NM_001130009
GEN1
Gen endonuclease homolog 1 (Drosophila)
chr16_-_31085073 23.283 ZNF668
zinc finger protein 668
chr18_-_72265038 23.277 LOC400657
uncharacterized LOC400657
chr14_+_69865095 22.703 NM_001252151
NM_001252152
SLC39A9

solute carrier family 39 (zinc transporter), member 9

chr14_+_69865380 22.319 NM_001252148
NM_001252150
NM_018375
SLC39A9


solute carrier family 39 (zinc transporter), member 9


chr6_+_111303240 22.133 NM_032194
RPF2
ribosome production factor 2 homolog (S. cerevisiae)
chr17_-_29641068 22.004 EVI2B
ecotropic viral integration site 2B
chr19_+_47759730 21.955 NM_015603
CCDC9
coiled-coil domain containing 9
chr19_+_47759802 21.568 CCDC9
coiled-coil domain containing 9
chr6_-_33239585 20.827 NM_022553
VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr2_+_17935124 20.825 NM_182625
GEN1
Gen endonuclease homolog 1 (Drosophila)
chr22_-_19512859 20.793 NM_001130861
NM_003277
CLDN5

claudin 5

chr19_+_50879681 20.019 NM_007121
NR1H2
nuclear receptor subfamily 1, group H, member 2
chr4_-_88450601 19.242 NM_001128310
NM_004684
SPARCL1

SPARC-like 1 (hevin)

chr4_-_88450243 19.011 SPARCL1
SPARC-like 1 (hevin)
chr6_-_33239439 18.968 VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr1_-_183559669 18.615 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr6_-_33168448 18.077 RXRB
retinoid X receptor, beta
chr3_-_15468981 17.326 NM_152396
METTL6
methyltransferase like 6
chr16_+_1583657 17.282 TMEM204
transmembrane protein 204
chr11_+_71791376 17.273 NM_001145307
NM_001145308
NM_001205138
NM_145309
LRTOMT



leucine rich transmembrane and 0-methyltransferase domain containing



chr18_-_53177999 17.162 NM_001243231
TCF4
transcription factor 4
chr5_+_87564840 17.090 LOC100505894
uncharacterized LOC100505894
chr8_+_38034066 16.973 NM_001204878
NM_004874
BAG4

BCL2-associated athanogene 4

chr1_+_198608216 16.970 PTPRC
protein tyrosine phosphatase, receptor type, C
chrX_-_70288155 16.938 NM_013346
SNX12
sorting nexin 12
chr16_+_30710461 16.789 NM_006662
SRCAP
Snf2-related CREBBP activator protein
chr18_+_11851388 16.686 NM_020412
CHMP1B
charged multivesicular body protein 1B
chrX_+_128913881 16.192 NM_018990
SASH3
SAM and SH3 domain containing 3
chr11_-_46722115 16.159 NM_004308
ARHGAP1
Rho GTPase activating protein 1
chr15_-_71184611 16.119 NM_020147
THAP10
THAP domain containing 10
chr3_+_150264514 16.076 NM_032025
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr3_+_15469052 15.841 NM_033083
EAF1
ELL associated factor 1
chr9_-_133454818 15.380 LOC100272217
uncharacterized LOC100272217
chr14_-_77923888 15.374 NM_001193314
NM_001193315
NM_001193316
NM_001193317
NM_022067
C14orf133




chromosome 14 open reading frame 133




chr17_-_29641094 15.309 NM_006495
EVI2B
ecotropic viral integration site 2B
chr15_+_71184781 15.259 NM_001199017
NM_017691
NM_001199018
LRRC49


leucine rich repeat containing 49


chr1_+_169337193 15.243 NM_003666
BLZF1
basic leucine zipper nuclear factor 1
chr6_+_31515391 15.074 NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr1_+_171810611 15.023 NM_001136127
NM_015569
DNM3

dynamin 3

chr7_+_106505696 14.883 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr19_-_39826625 14.789 GMFG
glia maturation factor, gamma
chrX_+_128913897 14.719 SASH3
SAM and SH3 domain containing 3
chr11_-_71791734 14.637 NUMA1
nuclear mitotic apparatus protein 1
chr2_+_234160317 14.630 ATG16L1
ATG16 autophagy related 16-like 1 (S. cerevisiae)
chr19_-_36505102 14.602 ALKBH6
alkB, alkylation repair homolog 6 (E. coli)
chr3_+_133494275 14.466 TF
transferrin
chr16_-_30366681 14.404 NM_006110
CD2BP2
CD2 (cytoplasmic tail) binding protein 2
chr21_-_46340874 14.334 NM_000211
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr16_+_2653350 14.146 LOC652276
potassium channel tetramerisation domain containing 5 pseudogene
chr19_+_3178735 14.145 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chr16_+_69166538 14.133 CIRH1A
cirrhosis, autosomal recessive 1A (cirhin)
chr11_-_75141015 14.052 KLHL35
kelch-like 35 (Drosophila)
chr11_+_63606535 14.026 MARK2
MAP/microtubule affinity-regulating kinase 2
chr8_+_38034296 13.981 BAG4
BCL2-associated athanogene 4
chr17_-_29641087 13.966 EVI2B
ecotropic viral integration site 2B
chr5_-_149535138 13.791 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr1_-_183560010 13.588 NM_001127651
NCF2
neutrophil cytosolic factor 2
chr10_-_72362441 13.558 PRF1
perforin 1 (pore forming protein)
chr3_-_128879873 13.427 NM_001204890
NM_001199469
NM_020701
ISY1-RAB43
ISY1

ISY1-RAB43 readthrough
ISY1 splicing factor homolog (S. cerevisiae)

chr11_-_72433379 13.423 NM_001135190
NM_015242
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr1_-_183559463 13.337 NCF2
neutrophil cytosolic factor 2
chr1_+_156698270 13.307 RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr1_+_198608136 13.284 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr11_-_62389571 13.251 NM_012200
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr2_-_69870837 13.090 AAK1
AP2 associated kinase 1
chr1_-_160313056 13.063 COPA
coatomer protein complex, subunit alpha
chr4_-_46911223 13.035 NM_130902
COX7B2
cytochrome c oxidase subunit VIIb2
chr8_+_27182995 12.962 NM_173176
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr6_-_32160289 12.931 GPSM3
G-protein signaling modulator 3
chr7_+_106505739 12.911 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr1_+_198608244 12.831 PTPRC
protein tyrosine phosphatase, receptor type, C
chr2_+_103035148 12.784 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr10_-_72362513 12.732 NM_001083116
NM_005041
PRF1

perforin 1 (pore forming protein)

chr8_+_121457642 12.720 NM_022045
MTBP
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr11_-_236833 12.674 SIRT3
sirtuin 3
chr22_+_37257004 12.632 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr5_-_1634099 12.615 LOC728613
programmed cell death 6 pseudogene
chr16_+_77225107 12.608 MON1B
MON1 homolog B (yeast)
chr8_+_27183047 12.481 PTK2B
PTK2B protein tyrosine kinase 2 beta
chr1_-_154193044 12.463 C1orf43
chromosome 1 open reading frame 43
chr5_-_130970851 12.460 RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6
chr19_+_16222706 12.456 RAB8A
RAB8A, member RAS oncogene family
chr5_-_88178964 12.389 MEF2C
myocyte enhancer factor 2C
chr1_+_168148215 12.206 TIPRL
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr5_-_93447237 12.058 NM_001163417
NM_001163418
NM_032042
FAM172A


family with sequence similarity 172, member A


chr2_-_69870705 12.055 AAK1
AP2 associated kinase 1
chr5_-_149535420 11.951 NM_002609
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr6_+_31553955 11.858 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr19_+_56186426 11.796 NM_001130072
NM_013333
EPN1

epsin 1

chr12_+_58138663 11.627 NM_005981
TSPAN31
tetraspanin 31
chr19_+_57752051 11.621 NM_001023563
NM_001145078
ZNF805

zinc finger protein 805

chr19_-_4723791 11.616 DPP9
dipeptidyl-peptidase 9
chr10_+_75545363 11.422 NM_001242487
NM_001242488
NM_015037
KIAA0913


KIAA0913


chr11_+_63606598 11.407 MARK2
MAP/microtubule affinity-regulating kinase 2
chr16_+_30484049 11.385 ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr1_-_150738255 11.361 CTSS
cathepsin S
chr1_+_111415791 11.357 CD53
CD53 molecule
chr20_+_10199455 11.356 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr19_-_36246411 11.325 HSPB6
heat shock protein, alpha-crystallin-related, B6
chr5_-_130970907 11.321 NM_001164386
NM_001164387
NM_001164388
NM_001164389
NM_001164390
NM_016340
RAPGEF6





Rap guanine nucleotide exchange factor (GEF) 6





chr12_+_112856701 11.314 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr3_-_58563490 11.268 NM_001076778
NM_007177
FAM107A

family with sequence similarity 107, member A

chr6_+_31515352 11.267 NM_001144961
NM_005007
NFKBIL1

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1

chr11_+_35684418 11.257 TRIM44
tripartite motif containing 44
chr17_+_18218569 11.216 NM_144775
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr17_-_19880991 11.204 NM_007202
AKAP10
A kinase (PRKA) anchor protein 10
chr6_+_31554475 11.193 NM_205837
LST1
leukocyte specific transcript 1
chr3_+_133465098 11.133 TF
transferrin
chr1_+_111415721 11.105 NM_000560
CD53
CD53 molecule
chrX_+_16737732 11.098 SYAP1
synapse associated protein 1
chr19_-_17375522 11.082 NM_031941
USHBP1
Usher syndrome 1C binding protein 1
chr14_-_93651242 11.076 NM_022151
MOAP1
modulator of apoptosis 1
chr20_-_48532036 11.024 SPATA2
spermatogenesis associated 2
chr19_+_16999871 10.937 F2RL3
coagulation factor II (thrombin) receptor-like 3
chr19_-_4723755 10.911 DPP9
dipeptidyl-peptidase 9
chr8_+_24772454 10.822 NM_001105541
NEFM
neurofilament, medium polypeptide
chr19_+_56186610 10.766 EPN1
epsin 1
chr6_+_122793061 10.751 NM_181794
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr9_-_130186491 10.741


chr19_+_15218141 10.728 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr17_-_29648631 10.717 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr19_+_56186580 10.690 EPN1
epsin 1
chr11_-_3862183 10.687 NM_001665
RHOG
ras homolog gene family, member G (rho G)
chr16_+_29674564 10.679 SPN
sialophorin
chrY_+_2709596 10.675 NM_001008
RPS4Y1
ribosomal protein S4, Y-linked 1
chr2_-_136873740 10.617 NM_001008540
CXCR4
chemokine (C-X-C motif) receptor 4
chrY_+_2709630 10.613 RPS4Y1
ribosomal protein S4, Y-linked 1
chr11_+_63606346 10.597 NM_001039469
NM_001163296
NM_001163297
NM_004954
MARK2



MAP/microtubule affinity-regulating kinase 2



chr4_+_40198526 10.500 NM_004310
RHOH
ras homolog gene family, member H
chr17_-_79269082 10.395 NM_001037984
NM_138570
SLC38A10

solute carrier family 38, member 10

chr1_+_156698250 10.337 NM_001142560
NM_015997
RRNAD1

ribosomal RNA adenine dimethylase domain containing 1

chr11_+_124492770 10.300 TBRG1
transforming growth factor beta regulator 1
chr5_+_80597401 10.290 NM_001131035
NM_001131036
NM_032280
ZCCHC9


zinc finger, CCHC domain containing 9


chr12_-_6233684 10.250 NM_000552
VWF
von Willebrand factor
chr17_-_34313685 10.231 NM_032962
NM_032963
CCL14

chemokine (C-C motif) ligand 14

chr18_-_29522988 10.212 TRAPPC8
trafficking protein particle complex 8
chr16_+_30483959 10.148 NM_001114380
NM_002209
ITGAL

integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)

chrX_+_103031797 10.119 PLP1
proteolipid protein 1
chr16_+_77224827 10.117 NM_014940
MON1B
MON1 homolog B (yeast)
chr19_+_56186569 10.056 EPN1
epsin 1
chr6_-_153323787 10.049 MTRF1L
mitochondrial translational release factor 1-like
chr2_+_175260455 10.028 NM_001193528
NM_024583
SCRN3

secernin 3

chr11_+_60739114 10.004 NM_006725
CD6
CD6 molecule
chr1_+_10003485 10.004 NM_022787
NMNAT1
nicotinamide nucleotide adenylyltransferase 1
chr8_-_82395401 9.990 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr1_-_160312959 9.941


chr11_-_64885124 9.932 NM_014205
ZNHIT2
zinc finger, HIT-type containing 2
chr19_-_42746743 9.897 GSK3A
glycogen synthase kinase 3 alpha
chr1_+_160313061 9.866 NM_015331
NCSTN
nicastrin
chr5_+_130506656 9.837 LYRM7
Lyrm7 homolog (mouse)
chr1_-_79472360 9.826 NM_022159
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr5_+_156820161 9.785 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr7_+_108210308 9.727 DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr2_+_233925035 9.652 NM_001017915
NM_005541
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr1_-_150738232 9.641 CTSS
cathepsin S
chrX_+_70586113 9.633 NM_004606
NM_138923
TAF1

TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa

chr5_+_153418544 9.632 MFAP3
microfibrillar-associated protein 3
chr7_+_156742402 9.624 NM_138400
NOM1
nucleolar protein with MIF4G domain 1
chr9_-_88969323 9.609 NM_001185059
NM_001185074
NM_024617
ZCCHC6


zinc finger, CCHC domain containing 6


chr19_-_39826676 9.609 NM_004877
GMFG
glia maturation factor, gamma
chr14_-_80677839 9.604 NM_001007023
NM_001242502
NM_001242503
NM_013989
DIO2



deiodinase, iodothyronine, type II



chr6_+_111580481 9.589 NM_153369
KIAA1919
KIAA1919
chr19_-_6481765 9.553 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr2_+_233925104 9.522 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr19_-_36236291 9.522 NM_001040425
NM_144987
U2AF1L4

U2 small nuclear RNA auxiliary factor 1-like 4

chr16_+_75681634 9.510 NM_018975
TERF2IP
telomeric repeat binding factor 2, interacting protein
chr19_-_4559713 9.489 NM_032108
SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr11_+_1874199 9.487 NM_002339
LSP1
lymphocyte-specific protein 1
chr17_-_37844266 9.433 NM_033419
PGAP3
post-GPI attachment to proteins 3
chr19_-_36399205 9.421 NM_001173514
NM_001173515
NM_003332
NM_198125
TYROBP



TYRO protein tyrosine kinase binding protein



chr8_+_22462286 9.415 KIAA1967
KIAA1967
chr5_-_79286793 9.350 NM_001010891
NM_001167741
MTX3

metaxin 3

chr19_-_36246206 9.343 HSPB6
heat shock protein, alpha-crystallin-related, B6
chr8_+_22462273 9.329 KIAA1967
KIAA1967
chr7_+_108210291 9.312 DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr19_-_36399183 9.289 TYROBP
TYRO protein tyrosine kinase binding protein
chr5_-_58652671 9.267 NM_001197219
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_+_86781869 9.259 NM_021145
DMTF1
cyclin D binding myb-like transcription factor 1
chr9_-_91793375 9.253 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr12_+_69742130 9.236 NM_000239
LYZ
lysozyme
chr7_+_86273951 9.229 GRM3
glutamate receptor, metabotropic 3
chr8_+_104427590 9.087 DCAF13
DDB1 and CUL4 associated factor 13
chr17_-_62084282 9.071 NM_000873
ICAM2
intercellular adhesion molecule 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.72 4.28e-28 GO:0002376 immune system process
1.92 5.03e-26 GO:0006955 immune response
1.20 4.59e-25 GO:0065007 biological regulation
1.13 1.42e-23 GO:0009987 cellular process
1.20 2.86e-22 GO:0050789 regulation of biological process
1.21 1.35e-20 GO:0050794 regulation of cellular process
1.32 5.86e-20 GO:0023052 signaling
1.34 2.01e-19 GO:0007165 signal transduction
1.29 1.36e-18 GO:0051716 cellular response to stimulus
1.80 1.09e-17 GO:0002682 regulation of immune system process
2.01 1.65e-17 GO:0002684 positive regulation of immune system process
1.44 2.58e-16 GO:0048583 regulation of response to stimulus
1.96 3.92e-16 GO:0050776 regulation of immune response
1.89 3.21e-15 GO:0001775 cell activation
1.65 4.58e-14 GO:0006952 defense response
1.19 1.15e-13 GO:0050896 response to stimulus
1.34 6.03e-13 GO:0006950 response to stress
2.08 1.10e-12 GO:0050778 positive regulation of immune response
1.39 6.03e-12 GO:0007166 cell surface receptor linked signaling pathway
2.10 6.09e-11 GO:0045321 leukocyte activation
2.28 6.30e-11 GO:0002764 immune response-regulating signaling pathway
1.55 8.05e-11 GO:0009611 response to wounding
2.28 1.55e-10 GO:0002757 immune response-activating signal transduction
2.13 1.57e-10 GO:0002253 activation of immune response
1.29 2.88e-10 GO:0048518 positive regulation of biological process
1.42 8.67e-10 GO:0035556 intracellular signal transduction
2.10 1.75e-09 GO:0051249 regulation of lymphocyte activation
2.00 4.40e-09 GO:0050865 regulation of cell activation
2.01 6.39e-09 GO:0002694 regulation of leukocyte activation
1.22 7.51e-09 GO:0019222 regulation of metabolic process
1.51 1.05e-08 GO:0006351 transcription, DNA-dependent
2.12 2.88e-08 GO:0050867 positive regulation of cell activation
1.47 3.33e-08 GO:0032774 RNA biosynthetic process
2.16 4.68e-08 GO:0051251 positive regulation of lymphocyte activation
1.78 5.28e-08 GO:0045087 innate immune response
2.10 9.56e-08 GO:0002696 positive regulation of leukocyte activation
1.50 1.89e-07 GO:0048584 positive regulation of response to stimulus
2.52 2.31e-07 GO:0050851 antigen receptor-mediated signaling pathway
1.27 5.26e-07 GO:0042221 response to chemical stimulus
1.17 8.02e-07 GO:0043170 macromolecule metabolic process
2.38 8.85e-07 GO:0002768 immune response-regulating cell surface receptor signaling pathway
2.20 1.13e-06 GO:0050870 positive regulation of T cell activation
1.82 1.43e-06 GO:0006954 inflammatory response
2.37 2.21e-06 GO:0002429 immune response-activating cell surface receptor signaling pathway
2.04 2.38e-06 GO:0050863 regulation of T cell activation
1.25 3.68e-06 GO:0048522 positive regulation of cellular process
1.36 3.85e-06 GO:0010033 response to organic substance
1.33 3.86e-06 GO:0065009 regulation of molecular function
1.97 4.17e-06 GO:0046649 lymphocyte activation
1.43 5.98e-06 GO:0051704 multi-organism process
1.20 6.31e-06 GO:0060255 regulation of macromolecule metabolic process
1.41 1.31e-05 GO:0042127 regulation of cell proliferation
1.33 1.40e-05 GO:0009966 regulation of signal transduction
1.19 1.66e-05 GO:0031323 regulation of cellular metabolic process
1.56 2.07e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.84 2.42e-05 GO:0030168 platelet activation
1.30 3.43e-05 GO:0023051 regulation of signaling
1.16 4.31e-05 GO:0044260 cellular macromolecule metabolic process
1.42 4.65e-05 GO:0040011 locomotion
1.27 5.55e-05 GO:0006464 protein modification process
2.46 5.87e-05 GO:0050852 T cell receptor signaling pathway
2.23 5.95e-05 GO:0010518 positive regulation of phospholipase activity
2.18 7.26e-05 GO:0060193 positive regulation of lipase activity
1.37 9.97e-05 GO:0006793 phosphorus metabolic process
1.37 9.97e-05 GO:0006796 phosphate metabolic process
2.24 1.00e-04 GO:0007202 activation of phospholipase C activity
1.67 1.03e-04 GO:0031347 regulation of defense response
2.17 1.13e-04 GO:0010517 regulation of phospholipase activity
1.50 1.40e-04 GO:0050878 regulation of body fluid levels
2.22 1.46e-04 GO:0010863 positive regulation of phospholipase C activity
1.53 1.51e-04 GO:0007599 hemostasis
2.05 1.63e-04 GO:0060191 regulation of lipase activity
1.97 2.14e-04 GO:0002697 regulation of immune effector process
1.32 2.20e-04 GO:0051239 regulation of multicellular organismal process
1.22 2.53e-04 GO:0048519 negative regulation of biological process
2.10 2.84e-04 GO:0042110 T cell activation
1.25 2.89e-04 GO:0043412 macromolecule modification
1.52 3.18e-04 GO:0007596 blood coagulation
1.52 3.18e-04 GO:0050817 coagulation
1.21 3.36e-04 GO:0009889 regulation of biosynthetic process
1.47 3.52e-04 GO:0042060 wound healing
1.97 3.68e-04 GO:0002252 immune effector process
1.17 3.78e-04 GO:0080090 regulation of primary metabolic process
1.56 4.22e-04 GO:0007243 intracellular protein kinase cascade
1.56 4.22e-04 GO:0023014 signal transduction via phosphorylation event
1.45 4.89e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.41 5.39e-04 GO:0006468 protein phosphorylation
1.20 6.18e-04 GO:0031326 regulation of cellular biosynthetic process
1.23 6.42e-04 GO:0065008 regulation of biological quality
1.50 7.36e-04 GO:0006935 chemotaxis
1.50 7.36e-04 GO:0042330 taxis
1.68 1.04e-03 GO:0001817 regulation of cytokine production
1.43 1.38e-03 GO:0071310 cellular response to organic substance
1.20 1.42e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.11 1.49e-03 GO:0044238 primary metabolic process
1.20 2.07e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.47 2.20e-03 GO:0080134 regulation of response to stress
1.20 2.40e-03 GO:0010468 regulation of gene expression
1.30 2.43e-03 GO:0050790 regulation of catalytic activity
1.98 2.45e-03 GO:0045089 positive regulation of innate immune response
1.25 2.66e-03 GO:0009059 macromolecule biosynthetic process
1.33 4.17e-03 GO:0009605 response to external stimulus
1.24 4.82e-03 GO:0016070 RNA metabolic process
1.24 5.05e-03 GO:0034645 cellular macromolecule biosynthetic process
1.35 5.17e-03 GO:0016310 phosphorylation
1.67 5.89e-03 GO:0030097 hemopoiesis
1.21 6.04e-03 GO:0090304 nucleic acid metabolic process
1.21 7.01e-03 GO:0048523 negative regulation of cellular process
1.59 8.14e-03 GO:0034097 response to cytokine stimulus
2.33 8.63e-03 GO:0031294 lymphocyte costimulation
2.33 8.63e-03 GO:0031295 T cell costimulation
1.36 8.66e-03 GO:0007155 cell adhesion
1.36 8.66e-03 GO:0022610 biological adhesion
1.53 8.77e-03 GO:0044419 interspecies interaction between organisms
1.35 8.89e-03 GO:0044093 positive regulation of molecular function
1.59 9.36e-03 GO:0019932 second-messenger-mediated signaling
2.05 1.01e-02 GO:0030098 lymphocyte differentiation
1.18 1.03e-02 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.80 1.03e-02 GO:0051272 positive regulation of cellular component movement
1.60 1.06e-02 GO:0051345 positive regulation of hydrolase activity
1.32 1.09e-02 GO:0070887 cellular response to chemical stimulus
1.61 1.19e-02 GO:0048534 hemopoietic or lymphoid organ development
1.82 1.27e-02 GO:0030335 positive regulation of cell migration
1.82 1.27e-02 GO:2000147 positive regulation of cell motility
2.33 1.37e-02 GO:0050864 regulation of B cell activation
1.17 1.39e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.78 1.40e-02 GO:0031349 positive regulation of defense response
1.89 1.44e-02 GO:0002521 leukocyte differentiation
2.55 1.48e-02 GO:0002274 myeloid leukocyte activation
1.09 1.65e-02 GO:0008152 metabolic process
1.80 1.75e-02 GO:0040017 positive regulation of locomotion
1.33 1.80e-02 GO:0009891 positive regulation of biosynthetic process
1.74 1.98e-02 GO:0045088 regulation of innate immune response
1.30 2.17e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.35 2.23e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.28 2.41e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.79 2.56e-02 GO:0050900 leukocyte migration
1.36 2.76e-02 GO:0019220 regulation of phosphate metabolic process
1.36 2.76e-02 GO:0051174 regulation of phosphorus metabolic process
1.61 2.95e-02 GO:0000165 MAPKKK cascade
2.25 3.01e-02 GO:0030217 T cell differentiation
2.01 3.20e-02 GO:0002758 innate immune response-activating signal transduction
1.40 3.53e-02 GO:0006928 cellular component movement
2.35 3.59e-02 GO:0045580 regulation of T cell differentiation
2.63 3.61e-02 GO:0030888 regulation of B cell proliferation
2.02 3.63e-02 GO:0002221 pattern recognition receptor signaling pathway
1.38 3.65e-02 GO:0009725 response to hormone stimulus
1.40 3.69e-02 GO:0051336 regulation of hydrolase activity
2.56 3.76e-02 GO:0050871 positive regulation of B cell activation
1.34 3.87e-02 GO:0016192 vesicle-mediated transport
1.34 3.99e-02 GO:2000026 regulation of multicellular organismal development
1.95 4.38e-02 GO:0050670 regulation of lymphocyte proliferation
1.26 4.54e-02 GO:0009893 positive regulation of metabolic process
1.55 4.55e-02 GO:0002520 immune system development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.26 5.18e-07 GO:0044459 plasma membrane part
1.14 3.27e-04 GO:0005886 plasma membrane
1.14 6.08e-04 GO:0071944 cell periphery
1.47 9.17e-04 GO:0005768 endosome
1.21 1.36e-03 GO:0005829 cytosol
1.05 2.43e-03 GO:0005622 intracellular
1.08 2.96e-03 GO:0005737 cytoplasm
1.05 3.31e-03 GO:0044424 intracellular part
1.26 4.06e-03 GO:0005887 integral to plasma membrane
1.81 4.52e-03 GO:0009897 external side of plasma membrane
1.24 1.92e-02 GO:0031226 intrinsic to plasma membrane
1.30 2.45e-02 GO:0031982 vesicle
1.29 3.08e-02 GO:0005615 extracellular space
3.74 3.90e-02 GO:0042101 T cell receptor complex
1.42 3.98e-02 GO:0009986 cell surface
1.29 4.28e-02 GO:0031410 cytoplasmic vesicle
1.82 4.36e-02 GO:0005924 cell-substrate adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.19 3.30e-20 GO:0005515 protein binding
1.09 2.45e-15 GO:0005488 binding
1.40 1.23e-06 GO:0001071 nucleic acid binding transcription factor activity
1.40 1.23e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.68 1.59e-04 GO:0032403 protein complex binding
2.74 1.21e-03 GO:0003823 antigen binding
2.60 1.42e-03 GO:0008009 chemokine activity
2.45 3.81e-03 GO:0042379 chemokine receptor binding
1.35 4.34e-03 GO:0019899 enzyme binding
2.25 1.20e-02 GO:0035591 signaling adaptor activity
1.85 1.55e-02 GO:0030674 protein binding, bridging
1.81 1.86e-02 GO:0060090 binding, bridging
2.34 2.29e-02 GO:0005070 SH3/SH2 adaptor activity