Motif ID: FOXL1.p2

Z-value: 1.118


Transcription factors associated with FOXL1.p2:

Gene SymbolEntrez IDGene Name
FOXL1 2300 forkhead box L1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXL1chr16_+_866121140.391.7e-09Click!


Activity profile for motif FOXL1.p2.

activity profile for motif FOXL1.p2


Sorted Z-values histogram for motif FOXL1.p2

Sorted Z-values for motif FOXL1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXL1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_39899749 37.318


chr17_-_29641068 30.144 EVI2B
ecotropic viral integration site 2B
chr17_-_29641087 29.895 EVI2B
ecotropic viral integration site 2B
chr3_-_12941547 27.498 IQSEC1
IQ motif and Sec7 domain 1
chr17_-_29641094 23.831 NM_006495
EVI2B
ecotropic viral integration site 2B
chr4_+_74269971 20.757 NM_000477
ALB
albumin
chr4_-_71532206 16.693 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr4_-_71532341 15.111 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr2_+_143886898 14.675 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr7_+_80267972 14.404 CD36
CD36 molecule (thrombospondin receptor)
chr4_-_84035888 14.377 PLAC8
placenta-specific 8
chr1_+_198608136 13.467 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr2_-_89165652 12.931


chr14_+_92788924 12.927 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr4_-_84035908 12.212 NM_001130715
NM_016619
PLAC8

placenta-specific 8

chr12_+_69742140 12.133 LYZ
lysozyme
chrX_+_37639246 10.877 NM_000397
CYBB
cytochrome b-245, beta polypeptide
chr2_+_143886969 10.531 ARHGAP15
Rho GTPase activating protein 15
chr14_+_21249209 10.245 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chr7_+_80267922 9.932 CD36
CD36 molecule (thrombospondin receptor)
chr17_-_29624249 9.859 NM_002544
OMG
oligodendrocyte myelin glycoprotein
chr1_+_198608216 9.624 PTPRC
protein tyrosine phosphatase, receptor type, C
chr17_+_28268622 9.039 NM_198529
EFCAB5
EF-hand calcium binding domain 5
chr3_-_121379757 8.853 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr11_+_92085261 8.821 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr2_+_189839078 8.804 NM_000090
COL3A1
collagen, type III, alpha 1
chrX_+_37639306 8.388 CYBB
cytochrome b-245, beta polypeptide
chr13_-_99959649 8.388 NM_004951
GPR183
G protein-coupled receptor 183
chr4_+_88754120 8.373 NM_001184695
NM_001184696
NM_001184697
NM_020203
MEPE



matrix extracellular phosphoglycoprotein



chr14_+_88471467 8.124 NM_003608
GPR65
G protein-coupled receptor 65
chr5_-_169724614 8.096 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_-_163172863 8.095 NM_003617
RGS5
regulator of G-protein signaling 5
chr12_+_25205180 8.055 NM_001204126
NM_001204127
NM_006152
LRMP


lymphoid-restricted membrane protein


chr17_-_67240955 7.967 NM_080282
ABCA10
ATP-binding cassette, sub-family A (ABC1), member 10
chr8_-_27941387 7.926 NM_001010906
C8orf80
chromosome 8 open reading frame 80
chr6_-_133078894 7.925 NM_001242350
NM_004665
VNN2

vanin 2

chr1_+_160336856 7.916 NM_005598
NHLH1
nescient helix loop helix 1
chr11_+_99426872 7.761 NM_175566
CNTN5
contactin 5
chr16_-_4292052 7.662 NM_001098814
SRL
sarcalumenin
chr7_+_80275967 7.543 CD36
CD36 molecule (thrombospondin receptor)
chr13_-_46742678 7.532 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr7_-_37025696 7.430 ELMO1
engulfment and cell motility 1
chr7_-_115608366 7.402 NM_001244583
TFEC
transcription factor EC
chr3_-_121379701 7.377 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_-_168513201 7.260 NM_003175
XCL1
XCL2
chemokine (C motif) ligand 1
chemokine (C motif) ligand 2
chr11_-_104905849 7.172 CASP1
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr2_-_224467049 7.112 SCG2
secretogranin II
chrX_-_106960268 6.906 NM_004089
TSC22D3
TSC22 domain family, member 3
chr5_-_41261539 6.884 NM_001115131
C6
complement component 6
chr12_-_10542616 6.788 NM_007360
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr4_+_88720701 6.772 NM_004967
IBSP
integrin-binding sialoprotein
chr12_-_91573264 6.702 NM_133503
DCN
decorin
chr5_-_42811959 6.670 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr6_-_108145507 6.645 NM_198081
SCML4
sex comb on midleg-like 4 (Drosophila)
chr1_+_104159953 6.624 NM_000699
AMY2A
amylase, alpha 2A (pancreatic)
chr13_-_48987247 6.482 LPAR6
lysophosphatidic acid receptor 6
chr12_-_52779362 6.408 NM_033045
KRT84
keratin 84
chr9_-_95244750 6.384 NM_001193335
NM_017680
ASPN

asporin

chr7_+_80267782 6.366 NM_000072
NM_001001548
CD36

CD36 molecule (thrombospondin receptor)

chr13_-_48987017 6.328 LPAR6
lysophosphatidic acid receptor 6
chr2_-_224467095 6.321 SCG2
secretogranin II
chr5_-_169724782 6.260 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr12_+_81101407 6.225 NM_002469
MYF6
myogenic factor 6 (herculin)
chr13_-_48987652 6.204 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chr14_-_107113943 6.181 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_-_32557431 6.144 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chrX_+_99839789 6.097 NM_022144
TNMD
tenomodulin
chr1_+_104097321 6.097 NM_020978
AMY2B
amylase, alpha 2B (pancreatic)
chr17_-_2996289 6.092 NM_002548
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr17_+_38119225 5.970 NM_178171
GSDMA
gasdermin A
chr7_+_80231503 5.935 NM_001001547
CD36
CD36 molecule (thrombospondin receptor)
chr4_-_153273683 5.912 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr4_-_70826712 5.874 NM_001891
CSN2
casein beta
chr1_+_168545710 5.834 NM_002995
XCL1
chemokine (C motif) ligand 1
chr4_+_74270832 5.820 ALB
albumin
chr1_-_161193375 5.812 NM_001643
APOA2
apolipoprotein A-II
chr4_-_155533800 5.798 FGG
fibrinogen gamma chain
chr4_-_155533882 5.782 NM_000509
NM_021870
FGG

fibrinogen gamma chain

chr3_+_122044010 5.737 NM_005213
CSTA
cystatin A (stefin A)
chr4_-_155533757 5.731 FGG
fibrinogen gamma chain
chr19_-_36499583 5.731 NM_001039876
C19orf46
chromosome 19 open reading frame 46
chr6_+_50786438 5.717 NM_003221
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr5_-_169724817 5.654 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr11_-_104972147 5.612 NM_001007232
NM_001223
NM_033292
NM_033293
NM_033294
NM_033295
CARD17
CASP1




caspase recruitment domain family, member 17
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)




chr1_-_150738292 5.606 NM_001199739
NM_004079
CTSS

cathepsin S

chr2_-_209010876 5.596 NM_005210
CRYGB
crystallin, gamma B
chr5_-_169724734 5.588 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_+_196621007 5.487 NM_000186
NM_001014975
CFH

complement factor H

chr15_+_93443418 5.383 NM_001042572
NM_001271
CHD2

chromodomain helicase DNA binding protein 2

chr1_+_198608244 5.314 PTPRC
protein tyrosine phosphatase, receptor type, C
chr5_+_156696351 5.310 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr4_+_113739203 5.274 NM_001127493
ANK2
ankyrin 2, neuronal
chr3_-_148939784 5.273 NM_000096
CP
ceruloplasmin (ferroxidase)
chr7_-_31380507 5.230 NM_022728
NEUROD6
neurogenic differentiation 6
chr4_-_155533850 5.204 FGG
fibrinogen gamma chain
chrX_-_135863502 5.163 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr19_+_50922194 5.131 NM_001243998
NM_001243999
NM_001244000
NM_003121
SPIB



Spi-B transcription factor (Spi-1/PU.1 related)



chr14_-_106733392 5.121 IGHG1
IGHG3
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr1_+_152974222 5.081 NM_001097589
NM_005416
SPRR3

small proline-rich protein 3

chr12_+_69742130 5.074 NM_000239
LYZ
lysozyme
chr1_+_196788860 5.033 NM_002113
CFHR1
complement factor H-related 1
chr2_+_211421322 4.884 NM_001875
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr7_-_113559048 4.875 NM_002711
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr3_-_49460110 4.872 NM_000481
NM_001164710
NM_001164711
NM_001164712
AMT



aminomethyltransferase



chr5_-_39203061 4.808 FYB
FYN binding protein
chr1_-_163172624 4.773 NM_001195303
RGS5
regulator of G-protein signaling 5
chr1_+_14031349 4.757 NM_012231
NM_015866
PRDM2

PR domain containing 2, with ZNF domain

chr4_+_88529680 4.750 NM_014208
DSPP
dentin sialophosphoprotein
chrX_+_64708614 4.711 NM_001010888
ZC3H12B
zinc finger CCCH-type containing 12B
chr12_+_25205488 4.688 LRMP
lymphoid-restricted membrane protein
chr1_+_63063186 4.642 NM_014495
ANGPTL3
angiopoietin-like 3
chr13_-_38172862 4.547 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr3_+_151531860 4.525 NM_001086
AADAC
arylacetamide deacetylase (esterase)
chr3_+_111261039 4.515 CD96
CD96 molecule
chr8_-_82395401 4.481 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr9_-_95244634 4.443 ASPN
asporin
chr17_+_26800657 4.439 NM_001145975
NM_001145976
NM_003984
SLC13A2


solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2


chr7_-_8302141 4.378 NM_004968
ICA1
islet cell autoantigen 1, 69kDa
chr1_-_36948914 4.363 NM_000760
NM_156039
NM_172313
CSF3R


colony stimulating factor 3 receptor (granulocyte)


chr17_-_29648631 4.356 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr5_+_67586466 4.349 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr16_+_24266873 4.341 NM_006539
CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr7_+_110731061 4.299 NM_001099658
NM_001099660
NM_018334
LRRN3


leucine rich repeat neuronal 3


chr11_-_5255712 4.254 NM_000519
HBD
hemoglobin, delta
chr7_+_107110501 4.236 NM_005295
GPR22
G protein-coupled receptor 22
chr6_+_26156552 4.225 HIST1H1E
histone cluster 1, H1e
chr8_-_102803178 4.210 NCALD
neurocalcin delta
chr12_-_10282680 4.209 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
CLEC7A





C-type lectin domain family 7, member A





chr13_-_46756326 4.207 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr19_+_9296269 4.205 NM_175883
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr9_-_95298251 4.194 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr3_-_58200397 4.194 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr6_+_72926144 4.192 NM_001168409
RIMS1
regulating synaptic membrane exocytosis 1
chr8_-_102803196 4.185 NCALD
neurocalcin delta
chr5_-_58295758 4.175 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_150738232 4.165 CTSS
cathepsin S
chr16_-_23724820 4.152 NM_033266
ERN2
endoplasmic reticulum to nucleus signaling 2
chr4_-_153303663 4.150 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr6_+_72922513 4.143 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr7_-_107443631 4.112 NM_000111
SLC26A3
solute carrier family 26, member 3
chr14_+_21359542 4.090 NM_002935
RNASE3
ribonuclease, RNase A family, 3
chr1_-_230849863 4.088 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr2_-_237172987 4.085 NM_212556
ASB18
ankyrin repeat and SOCS box containing 18
chr6_+_28317687 4.084 NM_001242894
NM_001242895
NM_024493
ZKSCAN3


zinc finger with KRAB and SCAN domains 3


chr16_+_72088507 4.067 NM_001126102
NM_005143
HP

haptoglobin

chr8_-_102803438 4.052 NM_032041
NCALD
neurocalcin delta
chr14_-_23285011 4.052 NM_001126105
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr10_-_69597768 4.029 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr16_+_2653350 4.011 LOC652276
potassium channel tetramerisation domain containing 5 pseudogene
chr5_+_156607847 3.995 NM_005546
ITK
IL2-inducible T-cell kinase
chr2_-_163008913 3.961 NM_002054
GCG
glucagon
chr21_-_31538970 3.959 NM_012131
CLDN17
claudin 17
chr1_-_161193190 3.905 APOA2
apolipoprotein A-II
chr20_+_47895168 3.884 ZNFX1-AS1
ZNFX1 antisense RNA 1 (non-protein coding)
chr17_+_5972425 3.828 WSCD1
WSC domain containing 1
chr3_+_101546833 3.827 NM_001005474
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr5_+_54320083 3.820 NM_002104
GZMK
granzyme K (granzyme 3; tryptase II)
chr11_+_10476665 3.815 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr10_-_98031154 3.798 NM_001114094
NM_013314
BLNK

B-cell linker

chr2_-_209028288 3.786 NM_014617
CRYGA
crystallin, gamma A
chr1_-_153518265 3.763 NM_002961
NM_019554
S100A4

S100 calcium binding protein A4

chr1_-_35324645 3.755 NM_001164824
C1orf212
chromosome 1 open reading frame 212
chr15_-_77176191 3.754 NM_020843
SCAPER
S-phase cyclin A-associated protein in the ER
chr4_-_39033981 3.751 NM_024943
TMEM156
transmembrane protein 156
chr12_-_7656285 3.727 NM_004244
NM_203416
CD163

CD163 molecule

chr8_-_27115935 3.721 STMN4
stathmin-like 4
chr1_-_7913490 3.718 NM_021995
UTS2
urotensin 2
chr12_-_15038724 3.715 NM_000900
NM_001190839
MGP

matrix Gla protein

chr1_+_156123321 3.688 NM_001193300
NM_022367
NM_001193302
SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chr16_-_21663908 3.684 IGSF6
immunoglobulin superfamily, member 6
chr19_-_14992166 3.681 NM_030901
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr3_-_49459870 3.641 AMT
aminomethyltransferase
chr11_-_47400096 3.625 NM_001080547
NM_003120
SPI1

spleen focus forming virus (SFFV) proviral integration oncogene spi1

chr14_-_106774311 3.609 IGHA1
immunoglobulin heavy constant alpha 1
chr12_-_9268513 3.606 A2M
alpha-2-macroglobulin
chr5_+_161112657 3.590 NM_000811
GABRA6
gamma-aminobutyric acid (GABA) A receptor, alpha 6
chr4_+_72102249 3.552 SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr12_-_9268522 3.534 NM_000014
A2M
alpha-2-macroglobulin
chr16_+_72097124 3.519 NM_020995
HPR
haptoglobin-related protein
chr10_+_225932 3.515 NM_001202467
NM_001202468
ZMYND11

zinc finger, MYND-type containing 11

chr8_-_87755880 3.479 NM_019098
CNGB3
cyclic nucleotide gated channel beta 3
chr2_+_113885145 3.454 IL1RN
interleukin 1 receptor antagonist
chr6_-_55740358 3.454 NM_021073
BMP5
bone morphogenetic protein 5
chr14_-_106539099 3.449 IGHA1
IGHG1
IGHG3
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr9_-_21166609 3.442 NM_002175
IFNA21
interferon, alpha 21
chr6_+_154407641 3.438 NM_001145287
OPRM1
opioid receptor, mu 1
chr2_+_132480063 3.428 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr21_-_15918635 3.427 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr18_+_61582744 3.425 NM_005024
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr5_-_58652671 3.411 NM_001197219
PDE4D
phosphodiesterase 4D, cAMP-specific
chr22_+_40322609 3.396 GRAP2
GRB2-related adaptor protein 2
chr4_+_71248794 3.367 NM_006685
SMR3B
submaxillary gland androgen regulated protein 3B
chr7_+_73624086 3.356 NM_014146
NM_032463
NM_032464
LAT2


linker for activation of T cells family, member 2


chr5_-_39270708 3.346 NM_001243093
FYB
FYN binding protein
chr4_+_68424444 3.332 NM_012108
STAP1
signal transducing adaptor family member 1
chr9_+_19290748 3.327 NM_017925
DENND4C
DENN/MADD domain containing 4C
chr1_-_93399531 3.297


chr6_-_55740387 3.294 BMP5
bone morphogenetic protein 5
chr14_-_107131217 3.260 IGHA1
immunoglobulin heavy constant alpha 1
chr5_-_146460991 3.251 NM_181677
NM_181678
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.64 1.54e-15 GO:0006955 immune response
1.46 9.57e-15 GO:0032501 multicellular organismal process
2.14 9.06e-14 GO:0002376 immune system process
1.37 4.04e-12 GO:0050896 response to stimulus
2.83 1.12e-10 GO:0050776 regulation of immune response
2.28 1.83e-10 GO:0006952 defense response
1.73 5.39e-09 GO:0048583 regulation of response to stimulus
2.26 2.71e-08 GO:0002682 regulation of immune system process
1.43 2.38e-07 GO:0023052 signaling
1.67 4.06e-07 GO:0007166 cell surface receptor linked signaling pathway
2.11 5.41e-07 GO:0007155 cell adhesion
2.11 5.41e-07 GO:0022610 biological adhesion
2.00 5.74e-07 GO:0009611 response to wounding
2.06 8.47e-07 GO:0048584 positive regulation of response to stimulus
2.87 1.32e-06 GO:0050778 positive regulation of immune response
2.30 1.45e-06 GO:0007186 G-protein coupled receptor protein signaling pathway
1.44 1.49e-06 GO:0007165 signal transduction
2.45 1.97e-06 GO:0002684 positive regulation of immune system process
1.65 3.31e-06 GO:0003008 system process
1.22 5.30e-06 GO:0065007 biological regulation
3.33 6.12e-06 GO:0003012 muscle system process
1.43 1.11e-05 GO:0048856 anatomical structure development
3.40 1.29e-05 GO:0006936 muscle contraction
1.38 1.69e-05 GO:0032502 developmental process
2.71 2.69e-05 GO:0006954 inflammatory response
2.95 2.70e-05 GO:0002253 activation of immune response
1.49 3.94e-05 GO:0006950 response to stress
1.71 4.32e-05 GO:0051239 regulation of multicellular organismal process
1.44 4.90e-05 GO:0048731 system development
6.50 7.23e-05 GO:0030049 muscle filament sliding
6.50 7.23e-05 GO:0033275 actin-myosin filament sliding
6.33 1.04e-04 GO:0070252 actin-mediated cell contraction
1.33 1.14e-04 GO:0051716 cellular response to stimulus
4.85 2.09e-04 GO:0072376 protein activation cascade
1.53 2.87e-04 GO:0048513 organ development
4.16 4.25e-04 GO:0006959 humoral immune response
2.32 4.97e-04 GO:0045087 innate immune response
2.11 5.53e-04 GO:0001775 cell activation
1.47 6.56e-04 GO:0065008 regulation of biological quality
3.86 6.84e-04 GO:0051216 cartilage development
1.35 7.32e-04 GO:0007275 multicellular organismal development
1.12 7.61e-04 GO:0009987 cellular process
2.39 2.41e-03 GO:0016337 cell-cell adhesion
5.81 3.03e-03 GO:0002455 humoral immune response mediated by circulating immunoglobulin
5.29 3.14e-03 GO:0006956 complement activation
1.38 4.13e-03 GO:0048518 positive regulation of biological process
1.18 4.55e-03 GO:0050789 regulation of biological process
2.72 4.64e-03 GO:0007517 muscle organ development
4.72 4.78e-03 GO:0030048 actin filament-based movement
4.02 7.03e-03 GO:0002449 lymphocyte mediated immunity
5.97 7.07e-03 GO:0006958 complement activation, classical pathway
2.52 9.16e-03 GO:0007601 visual perception
2.52 9.16e-03 GO:0050953 sensory perception of light stimulus
4.37 1.19e-02 GO:0016064 immunoglobulin mediated immune response
2.46 1.45e-02 GO:0032101 regulation of response to external stimulus
1.75 1.48e-02 GO:0007267 cell-cell signaling
4.29 1.48e-02 GO:0019724 B cell mediated immunity
1.42 1.58e-02 GO:0048869 cellular developmental process
2.60 1.60e-02 GO:0046649 lymphocyte activation
7.05 1.71e-02 GO:0019835 cytolysis
2.17 1.73e-02 GO:0051240 positive regulation of multicellular organismal process
3.75 1.76e-02 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
1.67 2.02e-02 GO:0050793 regulation of developmental process
1.42 2.25e-02 GO:0030154 cell differentiation
1.99 2.25e-02 GO:0051094 positive regulation of developmental process
2.29 2.36e-02 GO:0061061 muscle structure development
3.65 2.48e-02 GO:0002250 adaptive immune response
1.87 3.08e-02 GO:0051336 regulation of hydrolase activity
2.15 3.52e-02 GO:0031347 regulation of defense response
1.72 3.77e-02 GO:2000026 regulation of multicellular organismal development
1.89 3.83e-02 GO:0080134 regulation of response to stress
2.33 4.12e-02 GO:0045321 leukocyte activation
1.83 4.84e-02 GO:0050878 regulation of body fluid levels

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.83 1.05e-29 GO:0044421 extracellular region part
2.11 3.18e-26 GO:0005576 extracellular region
2.88 2.36e-23 GO:0005615 extracellular space
1.80 5.48e-15 GO:0044459 plasma membrane part
2.06 2.84e-13 GO:0005887 integral to plasma membrane
1.48 4.42e-13 GO:0071944 cell periphery
1.49 6.15e-13 GO:0005886 plasma membrane
2.02 1.23e-12 GO:0031226 intrinsic to plasma membrane
2.56 2.49e-07 GO:0031012 extracellular matrix
2.72 2.59e-07 GO:0005578 proteinaceous extracellular matrix
1.71 3.53e-05 GO:0000267 cell fraction
9.25 3.75e-05 GO:0032982 myosin filament
15.85 5.23e-05 GO:0005579 membrane attack complex
1.73 7.22e-04 GO:0005626 insoluble fraction
3.16 7.82e-04 GO:0043292 contractile fiber
3.19 1.16e-03 GO:0030016 myofibril
7.40 1.58e-03 GO:0016460 myosin II complex
1.69 3.05e-03 GO:0005624 membrane fraction
7.19 7.89e-03 GO:0005859 muscle myosin complex
2.95 1.07e-02 GO:0044449 contractile fiber part
1.18 1.07e-02 GO:0044425 membrane part
3.91 2.69e-02 GO:0031983 vesicle lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.62 1.72e-09 GO:0005125 cytokine activity
1.86 9.38e-07 GO:0005102 receptor binding
2.98 6.17e-05 GO:0005126 cytokine receptor binding
1.96 1.81e-04 GO:0005198 structural molecule activity
5.16 9.90e-04 GO:0008307 structural constituent of muscle
1.49 1.21e-03 GO:0004872 receptor activity
1.41 3.90e-03 GO:0004871 signal transducer activity
1.41 3.90e-03 GO:0060089 molecular transducer activity
1.77 6.23e-03 GO:0005509 calcium ion binding
1.53 6.65e-03 GO:0004888 transmembrane receptor activity
4.42 1.34e-02 GO:0008009 chemokine activity
3.99 3.73e-02 GO:0042379 chemokine receptor binding
3.24 4.66e-02 GO:0005201 extracellular matrix structural constituent
2.00 4.72e-02 GO:0003779 actin binding