Motif ID: FOXP3.p2

Z-value: 1.807


Transcription factors associated with FOXP3.p2:

Gene SymbolEntrez IDGene Name
FOXP3 50943 forkhead box P3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXP3chrX_-_491211710.704.5e-33Click!


Activity profile for motif FOXP3.p2.

activity profile for motif FOXP3.p2


Sorted Z-values histogram for motif FOXP3.p2

Sorted Z-values for motif FOXP3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXP3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_29641068 56.464 EVI2B
ecotropic viral integration site 2B
chr1_-_93399531 56.125


chr6_+_88117689 51.843 NM_001031743
C6orf165
chromosome 6 open reading frame 165
chr6_-_32497925 36.128 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr22_+_21986968 35.315 NM_152612
CCDC116
coiled-coil domain containing 116
chr16_-_70099755 35.017 PDXDC2P
pyridoxal-dependent decarboxylase domain containing 2, pseudogene
chr18_-_74728963 29.932 MBP
myelin basic protein
chr1_-_153029987 28.997 NM_005988
SPRR2A
small proline-rich protein 2A
chr18_-_74729049 28.069 NM_001025081
NM_001025090
NM_001025092
NM_002385
MBP



myelin basic protein



chr5_+_140213968 25.856 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr1_+_15990300 25.677


chr11_+_124824076 25.112 CCDC15
coiled-coil domain containing 15
chr16_+_31085722 24.443 NM_014699
ZNF646
zinc finger protein 646
chr1_+_66798095 24.148 PDE4B
phosphodiesterase 4B, cAMP-specific
chr11_+_62475165 23.992 GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr11_+_62475113 23.890 NM_012202
GNG3
guanine nucleotide binding protein (G protein), gamma 3
chrX_-_100641143 23.673 NM_000061
BTK
Bruton agammaglobulinemia tyrosine kinase
chr17_-_29641087 23.018 EVI2B
ecotropic viral integration site 2B
chr1_-_153044083 22.635 NM_001017418
SPRR2B
small proline-rich protein 2B
chrX_+_103031797 22.602 PLP1
proteolipid protein 1
chr3_-_58563070 22.502 FAM107A
family with sequence similarity 107, member A
chrX_+_8432870 22.107 NM_001001888
VCX3B
VCX3A
variable charge, X-linked 3B
variable charge, X-linked 3A
chr3_+_138066489 22.011 NM_001252091
NM_012219
MRAS

muscle RAS oncogene homolog

chr17_-_29641094 21.085 NM_006495
EVI2B
ecotropic viral integration site 2B
chr11_+_124824012 19.334 NM_025004
CCDC15
coiled-coil domain containing 15
chr4_+_86699846 19.138 NM_001042669
ARHGAP24
Rho GTPase activating protein 24
chr3_+_186560462 18.296 NM_001177800
NM_004797
ADIPOQ

adiponectin, C1Q and collagen domain containing

chr13_+_96085852 18.011 NM_001160100
NM_182848
CLDN10

claudin 10

chr16_+_31085751 17.631 ZNF646
zinc finger protein 646
chrX_-_13835187 16.840 GPM6B
glycoprotein M6B
chr1_+_158223926 16.690 NM_001763
CD1A
CD1a molecule
chr16_+_72097124 16.530 NM_020995
HPR
haptoglobin-related protein
chr12_-_10562744 16.461 NM_001199805
KLRC4-KLRK1
KLRC4-KLRK1 readthrough
chr11_+_116700620 16.401 NM_000040
APOC3
apolipoprotein C-III
chr16_+_72088507 15.770 NM_001126102
NM_005143
HP

haptoglobin

chr6_-_32557431 15.627 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr4_+_88896801 15.151 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr2_+_44502596 14.689 NM_000341
SLC3A1
solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1
chrX_-_106960268 14.508 NM_004089
TSC22D3
TSC22 domain family, member 3
chr12_-_8219001 14.401 C3AR1
complement component 3a receptor 1
chrM_+_4770 14.322


chr2_+_166152282 14.057 NM_001040143
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr6_-_11779279 13.699 NM_001143948
NM_032744
C6orf105

chromosome 6 open reading frame 105

chr3_+_186560478 13.596 ADIPOQ
adiponectin, C1Q and collagen domain containing
chrX_+_103031753 13.521 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr20_-_3644045 13.491 NM_022139
NM_145762
GFRA4

GDNF family receptor alpha 4

chr17_-_3337134 13.236 NM_003554
OR1E2
olfactory receptor, family 1, subfamily E, member 2
chr18_+_32173281 13.184 NM_001128175
NM_001198938
NM_001198939
NM_001198940
DTNA



dystrobrevin, alpha



chr1_-_13452655 12.961 NM_001024661
NM_001099854
PRAMEF13
PRAMEF14
PRAME family member 13
PRAME family member 14
chr6_-_167797917 12.959 NM_004610
TCP10
t-complex 10 homolog (mouse)
chr3_-_51533996 12.639 NM_001171904
NM_014703
VPRBP

Vpr (HIV-1) binding protein

chr12_+_51318515 12.309 NM_014033
METTL7A
methyltransferase like 7A
chr1_-_182922504 12.052 NM_030933
SHCBP1L
SHC SH2-domain binding protein 1-like
chr17_+_28268622 11.656 NM_198529
EFCAB5
EF-hand calcium binding domain 5
chr4_+_40198526 11.314 NM_004310
RHOH
ras homolog gene family, member H
chr8_-_37727937 11.297 RAB11FIP1
RAB11 family interacting protein 1 (class I)
chr1_+_203020310 11.185 NM_015053
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr20_+_24929862 11.123 NM_003650
CST7
cystatin F (leukocystatin)
chr12_-_8218930 11.116 NM_004054
C3AR1
complement component 3a receptor 1
chr17_-_2996289 11.077 NM_002548
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr1_-_153348057 10.879 NM_005621
S100A12
S100 calcium binding protein A12
chr2_+_189839132 10.785 COL3A1
collagen, type III, alpha 1
chr12_-_10282680 10.770 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
CLEC7A





C-type lectin domain family 7, member A





chr3_-_195310770 10.543 APOD
apolipoprotein D
chr18_+_13825542 10.019 NM_005913
MC5R
melanocortin 5 receptor
chr9_-_104198045 9.974 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr11_+_92085261 9.945 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr6_-_154677868 9.911 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chr4_+_71226477 9.750 NM_012390
SMR3B
SMR3A
submaxillary gland androgen regulated protein 3B
submaxillary gland androgen regulated protein 3A
chr9_-_116840545 9.628 AMBP
alpha-1-microglobulin/bikunin precursor
chr17_-_10421858 9.492 NM_005963
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr1_-_160549226 9.405 CD84
CD84 molecule
chr9_-_116840551 9.304 AMBP
alpha-1-microglobulin/bikunin precursor
chr5_-_135290521 9.045 NM_002302
LECT2
leukocyte cell-derived chemotaxin 2
chr22_-_39636906 9.029 NM_033016
PDGFB
platelet-derived growth factor beta polypeptide
chr4_+_88896899 9.019 SPP1
secreted phosphoprotein 1
chr22_+_18043147 8.994 NM_031481
SLC25A18
solute carrier family 25 (mitochondrial carrier), member 18
chr2_-_21225640 8.959 APOB
apolipoprotein B (including Ag(x) antigen)
chr5_+_140552201 8.732 NM_018940
PCDHB7
protocadherin beta 7
chr2_+_103035148 8.616 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr22_-_37499456 8.545 NM_153609
TMPRSS6
transmembrane protease, serine 6
chr7_+_142560512 8.528 EPHB6
EPH receptor B6
chr5_+_180415844 8.480 NM_197975
BTNL3
butyrophilin-like 3
chrX_-_49965003 8.417 NM_139289
AKAP4
A kinase (PRKA) anchor protein 4
chr9_-_116840460 8.389 AMBP
alpha-1-microglobulin/bikunin precursor
chr11_-_72380107 8.297 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr8_+_92114846 8.292 NM_001129890
LRRC69
leucine rich repeat containing 69
chr17_+_41052813 8.255 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr12_+_100897137 8.031 NM_001206992
NM_001206993
NR1H4

nuclear receptor subfamily 1, group H, member 4

chr10_+_114135013 7.587 NM_203380
ACSL5
acyl-CoA synthetase long-chain family member 5
chr15_+_43885251 7.574 NM_020990
CKMT1B
CKMT1A
creatine kinase, mitochondrial 1B
creatine kinase, mitochondrial 1A
chr19_+_52266640 7.568 NM_001462
FPR2
formyl peptide receptor 2
chr17_-_2966900 7.510 NM_014566
OR1D5
olfactory receptor, family 1, subfamily D, member 5
chr3_+_361365 7.324 NM_001253388
CHL1
cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr8_+_124194751 7.250 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr5_-_35118223 7.168 NM_001204314
NM_001204315
NM_001204316
NM_001204317
NM_001204318
PRLR




prolactin receptor




chrX_-_8139307 7.142 NM_016378
VCX2
variable charge, X-linked 2
chr11_-_8892909 7.101 ST5
suppression of tumorigenicity 5
chr9_-_116840604 7.054 AMBP
alpha-1-microglobulin/bikunin precursor
chr4_+_88896838 7.049 SPP1
secreted phosphoprotein 1
chr8_-_25282555 7.000 NM_000825
NM_001083111
GNRH1

gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)

chr12_-_3982394 6.938 NM_020367
PARP11
poly (ADP-ribose) polymerase family, member 11
chr11_-_62783281 6.865 NM_001184732
NM_001184733
NM_001184736
NM_004254
SLC22A8



solute carrier family 22 (organic anion transporter), member 8



chr5_+_161277702 6.853 NM_001127648
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr2_-_110962577 6.836 NM_000272
NM_001128178
NM_001128179
NM_207181
NPHP1



nephronophthisis 1 (juvenile)



chrX_-_106362050 6.812 NM_001171080
NM_018301
RBM41

RNA binding motif protein 41

chrX_-_101112548 6.691 NM_032946
NXF5
nuclear RNA export factor 5
chr1_-_173886464 6.615 NM_000488
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr1_+_46646199 6.559 TSPAN1
tetraspanin 1
chr16_+_31724564 6.511 ZNF720
zinc finger protein 720
chr11_-_85338313 6.496 NM_001142699
DLG2
discs, large homolog 2 (Drosophila)
chr6_-_31981049 6.360 NM_032470
TNXB
tenascin XB
chr11_-_57158103 6.311 NM_001243245
NM_002728
PRG2

proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)

chr3_-_42917191 6.251 CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr6_+_74104284 6.242 NM_018665
DDX43
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
chr7_-_150329285 6.240 GIMAP6
GTPase, IMAP family member 6
chr5_+_40909617 6.223 C7
complement component 7
chr12_-_10588543 6.220 NM_002260
KLRC2
KLRC3
killer cell lectin-like receptor subfamily C, member 2
killer cell lectin-like receptor subfamily C, member 3
chr9_-_21077804 6.169 NM_002176
IFNB1
interferon, beta 1, fibroblast
chr1_+_66797775 6.113 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr4_+_124317884 6.054 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr9_-_77503009 5.834 NM_017662
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr6_+_153019029 5.797 NM_025107
MYCT1
myc target 1
chr17_-_67240955 5.791 NM_080282
ABCA10
ATP-binding cassette, sub-family A (ABC1), member 10
chr2_-_110962539 5.776 NPHP1
nephronophthisis 1 (juvenile)
chr5_-_160112266 5.708 ATP10B
ATPase, class V, type 10B
chr19_-_6720585 5.707 NM_000064
C3
complement component 3
chr20_+_24929904 5.698 CST7
cystatin F (leukocystatin)
chr1_-_151804225 5.660 NM_005060
RORC
RAR-related orphan receptor C
chr5_+_54320083 5.625 NM_002104
GZMK
granzyme K (granzyme 3; tryptase II)
chr7_-_31380507 5.544 NM_022728
NEUROD6
neurogenic differentiation 6
chr2_+_189839113 5.533 COL3A1
collagen, type III, alpha 1
chr4_+_70146216 5.502 NM_001207004
NM_053039
UGT2B28

UDP glucuronosyltransferase 2 family, polypeptide B28

chr20_+_54933982 5.457 NM_080821
FAM210B
family with sequence similarity 210, member B
chr4_+_71587674 5.436 NM_001037442
NM_014961
RUFY3

RUN and FYVE domain containing 3

chr5_-_41213513 5.433 NM_000065
C6
complement component 6
chr2_+_189839078 5.421 NM_000090
COL3A1
collagen, type III, alpha 1
chr17_-_3301703 5.394 NM_003553
OR1E1
olfactory receptor, family 1, subfamily E, member 1
chr7_-_142659397 5.389 KEL
Kell blood group, metallo-endopeptidase
chr4_+_151503076 5.385 NM_006439
MAB21L2
mab-21-like 2 (C. elegans)
chr4_-_186732047 5.346 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr14_-_89016806 5.312 PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr22_-_50523853 5.223 MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr15_-_65412175 5.201 PDCD7
programmed cell death 7
chr6_+_71136141 5.199 NM_001162529
FAM135A
family with sequence similarity 135, member A
chr9_-_99064385 5.189 NM_000197
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3
chr6_+_31730772 4.964 NM_001039651
C6orf26
chromosome 6 open reading frame 26
chr3_+_115342302 4.942 GAP43
growth associated protein 43
chr7_-_107880492 4.940 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr17_+_41006094 4.939 AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr6_-_112041253 4.824 NM_153047
FYN
FYN oncogene related to SRC, FGR, YES
chr19_+_52298410 4.794 NM_002030
FPR3
formyl peptide receptor 3
chr9_-_117692874 4.779 NM_001244
NM_001252290
TNFSF8

tumor necrosis factor (ligand) superfamily, member 8

chr2_-_169887832 4.753 NM_003742
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr15_+_42696957 4.745 NM_173089
NM_173090
CAPN3

calpain 3, (p94)

chr13_+_23755059 4.718 NM_000231
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr11_+_71900601 4.697 NM_016724
NM_016725
FOLR1

folate receptor 1 (adult)

chr14_+_31494682 4.681 NM_001128126
NM_007077
AP4S1

adaptor-related protein complex 4, sigma 1 subunit

chr7_+_48211054 4.677 NM_152701
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
chr17_-_63822660 4.631 NM_001037325
CEP112
centrosomal protein 112kDa
chr1_-_173886401 4.615 SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr2_-_158300517 4.608 NM_004288
CYTIP
cytohesin 1 interacting protein
chr17_-_3512704 4.590 NM_080704
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr12_+_15475445 4.557 PTPRO
protein tyrosine phosphatase, receptor type, O
chr1_-_42630386 4.536 NM_033553
GUCA2A
guanylate cyclase activator 2A (guanylin)
chr6_+_33043702 4.533 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr17_+_6659356 4.507 XAF1
XIAP associated factor 1
chr11_-_66445318 4.506 RBM4B
RNA binding motif protein 4B
chr11_-_5526833 4.500 NM_001005567
OR51B5
HBE1
olfactory receptor, family 51, subfamily B, member 5
hemoglobin, epsilon 1
chrX_-_106362018 4.479 RBM41
RNA binding motif protein 41
chr7_-_92747269 4.473 SAMD9
sterile alpha motif domain containing 9
chr6_+_42952326 4.447 PPP2R5D
protein phosphatase 2, regulatory subunit B', delta
chr1_-_115238091 4.427 NM_000036
NM_001172626
AMPD1

adenosine monophosphate deaminase 1

chr22_-_38840032 4.398 NM_004981
KCNJ4
potassium inwardly-rectifying channel, subfamily J, member 4
chr15_-_93277303 4.394 FAM174B
family with sequence similarity 174, member B
chr19_+_21106058 4.371 NM_003429
ZNF85
zinc finger protein 85
chr17_+_27369917 4.248 NM_016518
PIPOX
pipecolic acid oxidase
chr9_-_116840673 4.236 NM_001633
AMBP
alpha-1-microglobulin/bikunin precursor
chr1_+_120049825 4.224 NM_000862
HSD3B1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
chr17_+_3118911 4.203 NM_014565
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr1_+_207627614 4.140 NM_001006658
NM_001877
CR2

complement component (3d/Epstein Barr virus) receptor 2

chr3_+_15469052 4.125 NM_033083
EAF1
ELL associated factor 1
chr11_-_66445218 4.114 NM_031492
RBM4B
RNA binding motif protein 4B
chrX_+_11311532 4.111 NM_001142
NM_182680
NM_182681
AMELX


amelogenin, X-linked


chr1_-_153321021 4.104 NM_020393
PGLYRP4
peptidoglycan recognition protein 4
chr2_-_178787522 4.067 NM_001077358
PDE11A
phosphodiesterase 11A
chr19_-_22193720 4.061 NM_007153
ZNF208
zinc finger protein 208
chr19_-_23578226 4.049 NM_003430
ZNF91
zinc finger protein 91
chr9_-_69202203 4.045 NM_001085476
FOXD4L6
forkhead box D4-like 6
chr7_+_123485222 4.013 NM_012269
HYAL4
hyaluronoglucosaminidase 4
chr1_-_150738232 4.012 CTSS
cathepsin S
chr6_+_106546736 4.012 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr10_+_96443250 3.866 NM_000772
NM_001128925
CYP2C18

cytochrome P450, family 2, subfamily C, polypeptide 18

chr17_-_66951381 3.866 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr12_+_53497273 3.842 NM_003578
SOAT2
sterol O-acyltransferase 2
chr20_-_44006876 3.823 NM_014477
TP53TG5
TP53 target 5
chr17_+_3100809 3.806 NM_012352
OR1A2
olfactory receptor, family 1, subfamily A, member 2
chrX_+_83116153 3.735 NM_021118
CYLC1
cylicin, basic protein of sperm head cytoskeleton 1
chr19_-_36304200 3.730 NM_021232
PRODH2
proline dehydrogenase (oxidase) 2
chr3_-_50608421 3.716 NM_001171741
C3orf18
chromosome 3 open reading frame 18

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.74 1.57e-10 GO:0002376 immune system process
1.53 3.83e-09 GO:0050896 response to stimulus
3.81 6.05e-08 GO:0050776 regulation of immune response
3.01 1.47e-07 GO:0006955 immune response
2.90 1.71e-07 GO:0006952 defense response
4.39 8.21e-07 GO:0050778 positive regulation of immune response
3.50 3.67e-06 GO:0002684 positive regulation of immune system process
4.69 6.14e-06 GO:0002253 activation of immune response
6.60 3.31e-05 GO:0002429 immune response-activating cell surface receptor signaling pathway
1.85 4.58e-05 GO:0042221 response to chemical stimulus
6.35 5.48e-05 GO:0002768 immune response-regulating cell surface receptor signaling pathway
2.72 7.42e-05 GO:0002682 regulation of immune system process
1.45 2.34e-04 GO:0032501 multicellular organismal process
3.33 3.75e-04 GO:0045087 innate immune response
2.34 6.92e-04 GO:0009611 response to wounding
1.51 7.46e-04 GO:0051716 cellular response to stimulus
3.91 1.21e-03 GO:0008202 steroid metabolic process
1.57 1.66e-03 GO:0007165 signal transduction
2.35 2.39e-03 GO:0048584 positive regulation of response to stimulus
1.52 2.60e-03 GO:0023052 signaling
4.18 4.45e-03 GO:0002757 immune response-activating signal transduction
5.63 5.26e-03 GO:0050851 antigen receptor-mediated signaling pathway
1.66 5.57e-03 GO:0006950 response to stress
4.08 5.92e-03 GO:0002764 immune response-regulating signaling pathway
4.06 6.35e-03 GO:0002696 positive regulation of leukocyte activation
3.99 7.81e-03 GO:0050867 positive regulation of cell activation
5.95 8.79e-03 GO:0006959 humoral immune response
4.06 1.29e-02 GO:0051251 positive regulation of lymphocyte activation
1.68 1.64e-02 GO:0065008 regulation of biological quality
2.62 1.66e-02 GO:0001775 cell activation
3.22 1.87e-02 GO:0006954 inflammatory response
1.74 2.36e-02 GO:0007166 cell surface receptor linked signaling pathway
6.92 2.41e-02 GO:0016064 immunoglobulin mediated immune response
13.99 2.68e-02 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
6.80 2.77e-02 GO:0019724 B cell mediated immunity
5.79 3.20e-02 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
7.93 3.26e-02 GO:0006956 complement activation
5.64 3.97e-02 GO:0002250 adaptive immune response
2.66 4.35e-02 GO:0071702 organic substance transport

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.74 7.02e-11 GO:0005886 plasma membrane
1.73 9.86e-11 GO:0071944 cell periphery
2.07 1.10e-08 GO:0005576 extracellular region
2.68 1.16e-06 GO:0005615 extracellular space
1.87 3.39e-06 GO:0044459 plasma membrane part
1.33 1.69e-05 GO:0016020 membrane
2.10 7.69e-05 GO:0005887 integral to plasma membrane
2.21 9.33e-05 GO:0044421 extracellular region part
2.06 1.36e-04 GO:0031226 intrinsic to plasma membrane
1.35 2.81e-04 GO:0044425 membrane part
1.39 3.51e-04 GO:0031224 intrinsic to membrane
2.29 3.54e-04 GO:0005626 insoluble fraction
1.39 5.27e-04 GO:0016021 integral to membrane
2.07 6.01e-04 GO:0000267 cell fraction
2.24 1.11e-03 GO:0005624 membrane fraction
3.05 2.76e-02 GO:0005792 microsome
13.59 3.38e-02 GO:0042613 MHC class II protein complex
2.95 3.99e-02 GO:0042598 vesicular fraction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.93 6.04e-05 GO:0004872 receptor activity
2.09 9.73e-05 GO:0004888 transmembrane receptor activity
1.68 3.61e-03 GO:0004871 signal transducer activity
1.68 3.61e-03 GO:0060089 molecular transducer activity
1.95 1.64e-02 GO:0005102 receptor binding