Motif ID: GATA6.p2

Z-value: 2.708


Transcription factors associated with GATA6.p2:

Gene SymbolEntrez IDGene Name
GATA6 2627 GATA binding protein 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GATA6chr18_+_197494030.186.2e-03Click!


Activity profile for motif GATA6.p2.

activity profile for motif GATA6.p2


Sorted Z-values histogram for motif GATA6.p2

Sorted Z-values for motif GATA6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA6.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_54689536 44.749 NM_006163
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr10_-_99531712 44.371 NM_003015
SFRP5
secreted frizzled-related protein 5
chr16_+_31539202 44.307 NM_016633
AHSP
alpha hemoglobin stabilizing protein
chr7_-_142659397 41.601 KEL
Kell blood group, metallo-endopeptidase
chr7_-_142659412 41.216 NM_000420
KEL
Kell blood group, metallo-endopeptidase
chrX_-_55057408 40.059 NM_000032
NM_001037967
NM_001037968
ALAS2


aminolevulinate, delta-, synthase 2


chr16_+_202853 38.754 NM_005332
HBZ
hemoglobin, zeta
chr1_-_158656487 38.278 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr19_-_13213973 37.907 NM_005583
LYL1
lymphoblastic leukemia derived sequence 1
chr8_-_86290333 36.257 NM_001128829
NM_001128830
NM_001128831
NM_001738
CA1



carbonic anhydrase I



chr22_+_23229959 35.716 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr11_+_92085261 34.388 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr19_-_12997956 34.143 NM_006563
KLF1
Kruppel-like factor 1 (erythroid)
chr6_-_33168448 32.923 RXRB
retinoid X receptor, beta
chr12_-_91576579 31.849 DCN
decorin
chr6_-_49604524 31.695 NM_000324
RHAG
Rh-associated glycoprotein
chr11_-_116708334 31.684 NM_000039
APOA1
apolipoprotein A-I
chr19_-_13213513 30.194 LYL1
lymphoblastic leukemia derived sequence 1
chr15_-_43513024 29.633 EPB42
erythrocyte membrane protein band 4.2
chr2_+_102927961 27.902 NM_016232
IL18R1
IL1RL1
interleukin 18 receptor 1
interleukin 1 receptor-like 1
chr6_+_41010236 27.060 NM_001010873
NM_001159726
TSPO2

translocator protein 2

chr12_+_69742130 27.054 NM_000239
LYZ
lysozyme
chr2_-_89442551 26.646 IGKC
IGK@
immunoglobulin kappa constant
immunoglobulin kappa locus
chr1_+_22303417 26.233 NM_007352
CELA3A
CELA3B
chymotrypsin-like elastase family, member 3A
chymotrypsin-like elastase family, member 3B
chr10_+_118305427 26.110 NM_000936
PNLIP
pancreatic lipase
chr12_-_114841702 25.999 NM_080718
TBX5
T-box 5
chr11_-_5255712 25.534 NM_000519
HBD
hemoglobin, delta
chr6_-_35765056 25.205 NM_001252597
NM_001252598
NM_001832
CLPS


colipase, pancreatic


chr12_-_120765555 24.777 NM_000928
PLA2G1B
phospholipase A2, group IB (pancreas)
chr4_-_144940439 24.512 NM_002100
GYPB
glycophorin B (MNS blood group)
chr7_+_130020289 23.533 NM_001868
CPA1
carboxypeptidase A1 (pancreatic)
chr7_-_100239136 23.103 NM_003227
TFR2
transferrin receptor 2
chr19_-_55668956 22.278 NM_000363
TNNI3
troponin I type 3 (cardiac)
chr11_+_71927818 21.797 NM_000803
NM_001113534
NM_001113535
NM_001113536
FOLR2



folate receptor 2 (fetal)



chr12_-_6233684 21.600 NM_000552
VWF
von Willebrand factor
chr15_-_43513234 21.413 NM_000119
NM_001114134
EPB42

erythrocyte membrane protein band 4.2

chr1_+_22328148 21.049 NM_005747
CELA3A
chymotrypsin-like elastase family, member 3A
chr9_-_117692874 20.684 NM_001244
NM_001252290
TNFSF8

tumor necrosis factor (ligand) superfamily, member 8

chr2_+_241808161 20.627 NM_000030
AGXT
alanine-glyoxylate aminotransferase
chr22_+_23213671 20.608 IGLV4-3
immunoglobulin lambda variable 4-3
chr21_-_39870303 20.529 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr12_-_91573264 20.517 NM_133503
DCN
decorin
chr7_+_142457318 20.448 NM_002769
PRSS1
PRSS2
protease, serine, 1 (trypsin 1)
protease, serine, 2 (trypsin 2)
chr1_+_159175048 20.375 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr9_-_97356007 19.890 NM_003837
FBP2
fructose-1,6-bisphosphatase 2
chr15_-_43513196 19.622 EPB42
erythrocyte membrane protein band 4.2
chr18_+_29171729 19.528 NM_000371
TTR
transthyretin
chr19_-_13213669 19.451 LYL1
lymphoblastic leukemia derived sequence 1
chr1_-_25747276 18.893 NM_020485
NM_138616
NM_138617
NM_138618
RHCE



RHD
Rh blood group, CcEe antigens



Rh blood group, D antigen
chr1_-_42630386 18.423 NM_033553
GUCA2A
guanylate cyclase activator 2A (guanylin)
chr16_-_20338808 18.372 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)



chr4_+_100495972 17.911 MTTP
microsomal triglyceride transfer protein
chr2_-_44065888 17.584 NM_022436
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr2_-_179672056 17.525 NM_003319
NM_133378
NM_133379
NM_133432
NM_133437
TTN




titin




chr14_-_21944826 17.504 NM_001163380
RAB2B
RAB2B, member RAS oncogene family
chr1_+_206317458 17.379 NM_001910
NM_148964
CTSE

cathepsin E

chr12_-_14996381 17.178 NM_021071
ART4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr11_-_57158103 17.029 NM_001243245
NM_002728
PRG2

proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)

chr6_-_46889620 16.773 NM_001098518
GPR116
G protein-coupled receptor 116
chr6_-_30128688 16.299 NM_006778
NM_052828
TRIM10

tripartite motif containing 10

chr19_-_55549612 16.074 NM_001083899
NM_016363
GP6

glycoprotein VI (platelet)

chr19_-_11494882 16.018 NM_000121
EPOR
erythropoietin receptor
chr19_+_36132646 15.625 NM_014209
ETV2
ets variant 2
chr1_-_114429996 15.544 BCL2L15
BCL2-like 15
chr4_-_144826659 15.464 NM_002102
NM_198682
GYPE

glycophorin E (MNS blood group)

chr14_-_94849552 15.431 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr19_+_10397642 15.375 NM_001039132
NM_001544
NM_022377
ICAM4


intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)


chr1_-_149858114 15.107 NM_003528
HIST2H2BE
histone cluster 2, H2be
chr1_+_119957553 14.916 NM_001166120
HSD3B2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr6_-_46047978 14.686 NM_001114086
CLIC5
chloride intracellular channel 5
chr2_-_152830448 14.550 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr1_-_93399531 14.497


chr8_-_38008332 14.464 NM_000349
STAR
steroidogenic acute regulatory protein
chr18_-_28742744 14.256 NM_004948
NM_024421
DSC1

desmocollin 1

chr3_-_167191808 14.217 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr16_+_71560022 14.120 NM_005769
NM_001166395
CHST4

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4

chr18_-_64271215 13.695 NM_021153
CDH19
cadherin 19, type 2
chr5_-_63257959 13.655 HTR1A
5-hydroxytryptamine (serotonin) receptor 1A
chr1_+_43291230 13.415 NM_018538
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr15_+_93443418 13.411 NM_001042572
NM_001271
CHD2

chromodomain helicase DNA binding protein 2

chr6_-_52710892 13.358 NM_153699
GSTA5
glutathione S-transferase alpha 5
chr10_-_104597079 13.256 NM_000102
CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
chr6_-_52668599 13.211 NM_145740
GSTA1
glutathione S-transferase alpha 1
chr3_-_137851123 13.177 NM_016161
A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chr2_+_189839113 13.145 COL3A1
collagen, type III, alpha 1
chr10_-_52645384 13.142 A1CF
APOBEC1 complementation factor
chr9_+_135937364 13.006 NM_001807
CEL
carboxyl ester lipase (bile salt-stimulated lipase)
chr22_+_51176623 12.996 NM_001097
ACR
acrosin
chr4_+_151503076 12.837 NM_006439
MAB21L2
mab-21-like 2 (C. elegans)
chr22_+_22723972 12.582


chr6_-_33168438 12.561 RXRB
retinoid X receptor, beta
chr3_+_186383770 12.161 NM_000412
HRG
histidine-rich glycoprotein
chr5_-_141338626 12.114 NM_016580
PCDH12
protocadherin 12
chr6_+_31674639 12.097 NM_001003693
LY6G6F
lymphocyte antigen 6 complex, locus G6F
chr2_+_189839132 12.071 COL3A1
collagen, type III, alpha 1
chr13_-_28543290 12.031 NM_001265
CDX2
caudal type homeobox 2
chr12_-_96390002 11.919 NM_002108
HAL
histidine ammonia-lyase
chr1_-_153044083 11.856 NM_001017418
SPRR2B
small proline-rich protein 2B
chr8_-_87755880 11.796 NM_019098
CNGB3
cyclic nucleotide gated channel beta 3
chr12_-_10542616 11.760 NM_007360
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chrX_+_15525430 11.757 NM_001721
BMX
BMX non-receptor tyrosine kinase
chr11_-_1036654 11.757 NM_005961
MUC6
mucin 6, oligomeric mucus/gel-forming
chr2_+_189839078 11.698 NM_000090
COL3A1
collagen, type III, alpha 1
chr19_-_51523272 11.563 NM_002776
NM_001077500
KLK10

kallikrein-related peptidase 10

chr4_-_74853819 11.458 NM_002704
PPBP
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr8_-_143961232 11.443 NM_000497
NM_001026213
CYP11B1

cytochrome P450, family 11, subfamily B, polypeptide 1

chr3_-_48040260 11.239 MAP4
microtubule-associated protein 4
chr3_-_52864687 11.233 NM_001166449
NM_002218
ITIH4

inter-alpha-trypsin inhibitor heavy chain family, member 4

chr18_-_44561967 11.214 NM_016427
TCEB3B
transcription elongation factor B polypeptide 3B (elongin A2)
chr8_-_93107442 11.176 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr2_-_208994408 11.068 NM_020989
CRYGC
crystallin, gamma C
chr10_-_13749622 10.986 FRMD4A
FERM domain containing 4A
chr17_-_47841468 10.972 FAM117A
family with sequence similarity 117, member A
chr1_-_155271186 10.895 NM_000298
PKLR
pyruvate kinase, liver and RBC
chr8_-_20040612 10.842 NM_001135691
NM_001142324
NM_001142325
NM_003053
SLC18A1



solute carrier family 18 (vesicular monoamine), member 1



chr5_-_35118223 10.807 NM_001204314
NM_001204315
NM_001204316
NM_001204317
NM_001204318
PRLR




prolactin receptor




chr17_+_3100809 10.690 NM_012352
OR1A2
olfactory receptor, family 1, subfamily A, member 2
chr14_-_107013122 10.627 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr16_-_11375094 10.612 NM_002761
PRM1
protamine 1
chr17_-_3819692 10.569 P2RX1
purinergic receptor P2X, ligand-gated ion channel, 1
chr6_-_42690308 10.426 NM_000322
PRPH2
peripherin 2 (retinal degeneration, slow)
chr9_+_33240165 10.422 NM_014471
SPINK4
serine peptidase inhibitor, Kazal type 4
chr8_+_70378858 10.393 NM_001128204
NM_015170
SULF1

sulfatase 1

chr5_-_135290521 10.393 NM_002302
LECT2
leukocyte cell-derived chemotaxin 2
chr4_-_120243257 10.342 NM_000134
FABP2
fatty acid binding protein 2, intestinal
chr12_+_53818864 10.332 AMHR2
anti-Mullerian hormone receptor, type II
chr2_+_220378891 10.299 NM_018674
NM_182847
ACCN4

amiloride-sensitive cation channel 4, pituitary

chr19_-_40919270 10.229 NM_020956
NM_181882
PRX

periaxin

chr6_-_49712055 10.143 NM_001190986
NM_006061
CRISP3

cysteine-rich secretory protein 3

chr10_-_52645430 9.860 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr11_-_47374221 9.858 NM_000256
MYBPC3
myosin binding protein C, cardiac
chr17_-_62084282 9.828 NM_000873
ICAM2
intercellular adhesion molecule 2
chr11_-_125550674 9.821 NM_001612
NM_020069
NM_020107
NM_020108
ACRV1



acrosomal vesicle protein 1



chr9_-_21142143 9.811 NM_002177
IFNW1
interferon, omega 1
chr10_+_7745354 9.656 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr1_+_171217632 9.654 NM_002021
FMO1
flavin containing monooxygenase 1
chr8_+_105352050 9.539 NM_030788
TM7SF4
transmembrane 7 superfamily member 4
chr7_-_99332715 9.528 NM_000765
CYP3A7
CYP3A5
cytochrome P450, family 3, subfamily A, polypeptide 7
cytochrome P450, family 3, subfamily A, polypeptide 5
chr17_-_2966900 9.445 NM_014566
OR1D5
olfactory receptor, family 1, subfamily D, member 5
chr12_-_10562744 9.434 NM_001199805
KLRC4-KLRK1
KLRC4-KLRK1 readthrough
chr8_-_145701717 9.382 NM_003923
FOXH1
forkhead box H1
chr20_+_43935490 9.151 NM_014276
RBPJL
recombination signal binding protein for immunoglobulin kappa J region-like
chr5_-_160112266 9.102 ATP10B
ATPase, class V, type 10B
chr17_-_64225496 9.056 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr5_+_155754172 9.041 SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr2_-_219850273 8.937 NM_017521
FEV
FEV (ETS oncogene family)
chr6_+_160327972 8.903 NM_002377
MAS1
MAS1 oncogene
chr22_+_22735134 8.870 CYAT1
immunoglobulin lambda light chain-like
chr3_-_187009469 8.848 NM_001031849
NM_001879
NM_139125
MASP1


mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)


chr9_-_95244634 8.831 ASPN
asporin
chr10_+_7745284 8.831 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr3_+_88188261 8.798 NM_018293
ZNF654
zinc finger protein 654
chr14_+_88852065 8.786 SPATA7
spermatogenesis associated 7
chr18_+_43304143 8.774 SLC14A1
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr9_+_33795558 8.764 NM_002771
PRSS3
protease, serine, 3
chr10_+_7745229 8.729 NM_002216
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_98064084 8.679 NM_001017520
NM_004088
DNTT

deoxynucleotidyltransferase, terminal

chr8_+_124194751 8.557 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr5_-_154230212 8.483 NM_032385
C5orf4
chromosome 5 open reading frame 4
chr14_-_21270537 8.470 NM_198232
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr4_+_120056938 8.465 NM_016599
MYOZ2
myozenin 2
chr3_-_50649110 8.410 NM_013324
NM_145071
CISH

cytokine inducible SH2-containing protein

chr17_+_8213555 8.395 NM_173728
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chr2_+_138721807 8.386 NM_001024074
NM_001024075
NM_006895
HNMT


histamine N-methyltransferase


chr9_+_125137600 8.374 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr11_-_128712340 8.241 NM_000220
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr17_+_38171613 8.212 NM_000759
NM_001178147
NM_172219
NM_172220
CSF3



colony stimulating factor 3 (granulocyte)



chr13_-_30881141 8.157 NM_001014380
KATNAL1
katanin p60 subunit A-like 1
chr9_-_95244750 8.134 NM_001193335
NM_017680
ASPN

asporin

chr12_-_13248581 8.109 NM_001206843
NM_001206845
NM_031289
NM_153823
GSG1



germ cell associated 1



chr2_-_206950895 8.097 NM_017759
INO80D
INO80 complex subunit D
chr8_-_93107643 8.089 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_-_159094163 8.074 NM_001031700
NM_001128424
FAM198B

family with sequence similarity 198, member B

chr22_-_42526877 8.062 NM_000106
NM_001025161
CYP2D6

cytochrome P450, family 2, subfamily D, polypeptide 6

chr1_+_17248425 8.052 NM_014675
CROCC
ciliary rootlet coiled-coil, rootletin
chr9_+_125796845 8.009 NM_005294
GPR21
G protein-coupled receptor 21
chr1_+_199996729 7.972 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2

chr15_+_74466171 7.962 ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr4_-_70626429 7.927 NM_014465
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr19_-_48389571 7.915 NM_003167
SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr4_+_78432905 7.879 NM_006419
CXCL13
chemokine (C-X-C motif) ligand 13
chrX_+_38211735 7.840 NM_000531
OTC
ornithine carbamoyltransferase
chr22_+_22550159 7.835 IGLV6-57
immunoglobulin lambda variable 6-57
chr5_+_143191725 7.810 NM_021182
HMHB1
histocompatibility (minor) HB-1
chr11_-_57148602 7.803 NM_006093
PRG3
proteoglycan 3
chr3_-_15563160 7.774 NM_005677
NM_080539
COLQ

collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase

chr18_+_19749403 7.772 NM_005257
GATA6
GATA binding protein 6
chr2_+_169757749 7.749 NM_001081686
NM_021176
G6PC2

glucose-6-phosphatase, catalytic, 2

chrX_-_45060081 7.676 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chrX_+_99839789 7.650 NM_022144
TNMD
tenomodulin
chr3_-_101039403 7.618 NM_016247
IMPG2
interphotoreceptor matrix proteoglycan 2
chr8_-_93075190 7.486 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr12_-_6055397 7.464 NM_020373
ANO2
anoctamin 2
chr1_-_116311330 7.462 CASQ2
calsequestrin 2 (cardiac muscle)
chr8_-_41655139 7.447 NM_000037
NM_020475
NM_020476
NM_020477
ANK1



ankyrin 1, erythrocytic



chr19_-_48389514 7.382 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr19_-_48547180 7.337 NM_019855
CABP5
calcium binding protein 5
chr3_-_57234279 7.193 NM_003865
HESX1
HESX homeobox 1
chrX_-_78623006 7.183 NM_001171581
NM_004867
ITM2A

integral membrane protein 2A

chr1_-_11907741 7.154 NM_006172
NPPA
natriuretic peptide A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.64 3.68e-20 GO:0032501 multicellular organismal process
2.10 1.93e-17 GO:0065008 regulation of biological quality
1.47 8.58e-14 GO:0050896 response to stimulus
7.25 4.19e-13 GO:0007586 digestion
4.38 2.78e-11 GO:0008202 steroid metabolic process
5.51 9.10e-11 GO:0006805 xenobiotic metabolic process
5.51 9.10e-11 GO:0071466 cellular response to xenobiotic stimulus
5.46 1.12e-10 GO:0009410 response to xenobiotic stimulus
2.41 2.47e-10 GO:0006629 lipid metabolic process
1.77 7.13e-09 GO:0042221 response to chemical stimulus
2.33 1.57e-08 GO:0009611 response to wounding
2.74 1.68e-08 GO:0050878 regulation of body fluid levels
2.79 1.17e-07 GO:0007599 hemostasis
1.84 2.23e-07 GO:0003008 system process
2.76 2.96e-07 GO:0007596 blood coagulation
2.76 2.96e-07 GO:0050817 coagulation
3.90 7.30e-07 GO:0003013 circulatory system process
3.90 7.30e-07 GO:0008015 blood circulation
2.66 1.45e-06 GO:0001775 cell activation
2.50 1.79e-06 GO:0042060 wound healing
3.56 1.81e-06 GO:0030168 platelet activation
1.45 2.43e-06 GO:0051716 cellular response to stimulus
1.27 3.86e-06 GO:0065007 biological regulation
1.52 7.70e-06 GO:0048856 anatomical structure development
1.56 9.63e-06 GO:0048731 system development
2.35 2.26e-05 GO:0048878 chemical homeostasis
1.69 3.98e-05 GO:0048513 organ development
4.61 4.95e-05 GO:0008217 regulation of blood pressure
2.03 1.20e-04 GO:0042592 homeostatic process
1.84 1.68e-04 GO:0002376 immune system process
1.41 3.14e-04 GO:0032502 developmental process
5.44 4.13e-04 GO:0019748 secondary metabolic process
5.05 4.29e-04 GO:0002576 platelet degranulation
1.41 5.00e-04 GO:0023052 signaling
2.75 5.21e-04 GO:0032787 monocarboxylic acid metabolic process
2.15 5.27e-04 GO:0044255 cellular lipid metabolic process
6.46 1.34e-03 GO:0003073 regulation of systemic arterial blood pressure
1.41 1.46e-03 GO:0007275 multicellular organismal development
1.14 1.59e-03 GO:0009987 cellular process
3.53 2.01e-03 GO:0042445 hormone metabolic process
1.88 2.36e-03 GO:0070887 cellular response to chemical stimulus
4.71 2.63e-03 GO:0034754 cellular hormone metabolic process
2.96 2.69e-03 GO:0007601 visual perception
2.96 2.69e-03 GO:0050953 sensory perception of light stimulus
2.30 2.71e-03 GO:0050801 ion homeostasis
3.11 3.16e-03 GO:0010817 regulation of hormone levels
2.66 5.65e-03 GO:0006954 inflammatory response
12.62 5.97e-03 GO:0008211 glucocorticoid metabolic process
12.62 5.97e-03 GO:0044241 lipid digestion
1.56 6.38e-03 GO:0048583 regulation of response to stimulus
6.16 6.96e-03 GO:0006721 terpenoid metabolic process
2.27 7.11e-03 GO:0050776 regulation of immune response
8.08 7.30e-03 GO:0008207 C21-steroid hormone metabolic process
1.39 7.46e-03 GO:0007165 signal transduction
4.97 8.47e-03 GO:0072376 protein activation cascade
15.78 1.02e-02 GO:0006704 glucocorticoid biosynthetic process
1.92 1.18e-02 GO:0007155 cell adhesion
1.92 1.18e-02 GO:0022610 biological adhesion
3.26 1.23e-02 GO:0002697 regulation of immune effector process
2.22 1.51e-02 GO:0055082 cellular chemical homeostasis
8.84 1.54e-02 GO:0072378 blood coagulation, fibrin clot formation
2.24 1.66e-02 GO:0071702 organic substance transport
2.24 1.75e-02 GO:0006873 cellular ion homeostasis
7.21 1.89e-02 GO:0030195 negative regulation of blood coagulation
1.45 2.18e-02 GO:0006950 response to stress
8.42 2.23e-02 GO:0001990 regulation of systemic arterial blood pressure by hormone
20.20 2.46e-02 GO:0006705 mineralocorticoid biosynthetic process
20.20 2.46e-02 GO:0008212 mineralocorticoid metabolic process
6.96 2.52e-02 GO:0050819 negative regulation of coagulation
1.89 4.19e-02 GO:0006082 organic acid metabolic process
9.47 4.51e-02 GO:0006700 C21-steroid hormone biosynthetic process
1.85 4.56e-02 GO:0006955 immune response
1.79 4.79e-02 GO:0040011 locomotion
1.89 4.79e-02 GO:0019752 carboxylic acid metabolic process
1.89 4.79e-02 GO:0043436 oxoacid metabolic process
1.73 5.00e-02 GO:0009605 response to external stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.25 7.40e-23 GO:0005576 extracellular region
2.74 4.58e-19 GO:0044421 extracellular region part
2.88 2.19e-16 GO:0005615 extracellular space
1.95 1.59e-14 GO:0044459 plasma membrane part
2.31 3.71e-14 GO:0031226 intrinsic to plasma membrane
2.31 7.40e-14 GO:0005887 integral to plasma membrane
1.55 8.53e-12 GO:0071944 cell periphery
1.56 1.12e-11 GO:0005886 plasma membrane
2.12 5.92e-09 GO:0000267 cell fraction
2.17 3.94e-07 GO:0005626 insoluble fraction
2.18 6.38e-07 GO:0005624 membrane fraction
1.28 5.39e-05 GO:0044425 membrane part
2.49 1.42e-04 GO:0009986 cell surface
1.22 2.51e-04 GO:0016020 membrane
1.29 3.15e-04 GO:0031224 intrinsic to membrane
3.03 3.89e-04 GO:0030141 stored secretory granule
2.81 6.22e-04 GO:0005792 microsome
2.71 1.16e-03 GO:0042598 vesicular fraction
1.27 2.10e-03 GO:0016021 integral to membrane
2.31 2.18e-03 GO:0031012 extracellular matrix
2.75 3.24e-03 GO:0045177 apical part of cell
4.87 3.42e-03 GO:0031091 platelet alpha granule
4.86 8.75e-03 GO:0031983 vesicle lumen
3.11 9.31e-03 GO:0009897 external side of plasma membrane
2.86 1.10e-02 GO:0016324 apical plasma membrane
3.27 1.51e-02 GO:0030016 myofibril
4.84 2.25e-02 GO:0031093 platelet alpha granule lumen
4.73 2.67e-02 GO:0034774 secretory granule lumen
3.08 2.98e-02 GO:0043292 contractile fiber
4.55 3.71e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
3.13 4.23e-02 GO:0044449 contractile fiber part

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.66 1.81e-06 GO:0008289 lipid binding
1.73 5.53e-06 GO:0004872 receptor activity
1.93 2.52e-05 GO:0005102 receptor binding
6.73 5.98e-05 GO:0019825 oxygen binding
5.44 9.85e-05 GO:0005496 steroid binding
3.25 1.09e-04 GO:0005125 cytokine activity
1.57 1.66e-04 GO:0004871 signal transducer activity
1.57 1.66e-04 GO:0060089 molecular transducer activity
3.09 1.41e-03 GO:0005126 cytokine receptor binding
3.47 2.14e-03 GO:0046906 tetrapyrrole binding
3.49 3.63e-03 GO:0020037 heme binding
7.21 4.50e-03 GO:0015020 glucuronosyltransferase activity
1.64 6.13e-03 GO:0004888 transmembrane receptor activity
4.10 7.33e-03 GO:0004497 monooxygenase activity
3.02 9.15e-03 GO:0001871 pattern binding
3.02 9.15e-03 GO:0030247 polysaccharide binding
9.47 1.08e-02 GO:0008395 steroid hydroxylase activity
2.21 1.25e-02 GO:0030246 carbohydrate binding
3.05 1.30e-02 GO:0031406 carboxylic acid binding
3.77 1.84e-02 GO:0004867 serine-type endopeptidase inhibitor activity
3.79 3.51e-02 GO:0005201 extracellular matrix structural constituent
2.92 3.77e-02 GO:0005539 glycosaminoglycan binding
2.56 3.99e-02 GO:0005506 iron ion binding
3.27 4.67e-02 GO:0019955 cytokine binding