Motif ID: GAUUGUC

Z-value: 1.021


Mature miRNA associated with seed GAUUGUC:

NamemiRBase Accession
hsa-miR-219-5p MIMAT0000276
hsa-miR-4782-3p MIMAT0019945



Activity profile for motif GAUUGUC.

activity profile for motif GAUUGUC


Sorted Z-values histogram for motif GAUUGUC

Sorted Z-values for motif GAUUGUC



Network of associatons between targets according to the STRING database.



First level regulatory network of GAUUGUC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_167298280 13.210 NM_001198783
POU2F1
POU class 2 homeobox 1
chr16_+_85646923 13.038 NM_014615
KIAA0182
KIAA0182
chr16_+_85645014 12.751 NM_001134473
KIAA0182
KIAA0182
chr6_+_47445440 12.744 NM_012120
CD2AP
CD2-associated protein
chr4_-_109089444 11.771 NM_001130713
NM_001130714
NM_016269
LEF1


lymphoid enhancer-binding factor 1


chr17_-_29151724 11.238 NM_015986
CRLF3
cytokine receptor-like factor 3
chr16_-_89007605 9.865 NM_175931
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr16_-_89043215 9.692 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr4_-_109087876 9.364 NM_001166119
LEF1
lymphoid enhancer-binding factor 1
chr7_+_101460881 8.999 NM_181552
CUX1
cut-like homeobox 1
chr5_+_112312392 8.847 NM_001242377
NM_152624
DCP2

DCP2 decapping enzyme homolog (S. cerevisiae)

chr1_+_167189948 8.729 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr15_-_61521478 8.688 NM_134261
RORA
RAR-related orphan receptor A
chr4_+_38665587 8.508 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr15_-_60884615 8.445 NM_134262
RORA
RAR-related orphan receptor A
chr3_+_187871473 8.435 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr15_-_60919642 7.761 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr12_-_56652118 7.726 NM_173595
ANKRD52
ankyrin repeat domain 52
chr3_+_187943192 7.582 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_+_2985730 7.203 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr19_+_1407531 7.077 NM_018959
NM_170711
DAZAP1

DAZ associated protein 1

chr3_+_187930720 6.779 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr4_+_1902352 6.776 NM_133334
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr1_-_31230673 6.587 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr12_-_24102563 6.283 NM_006940
SOX5
SRY (sex determining region Y)-box 5
chr4_+_57774035 6.231 NM_005612
REST
RE1-silencing transcription factor
chr14_+_64682671 6.153 NM_182910
SYNE2
spectrin repeat containing, nuclear envelope 2
chr6_-_86352635 6.062 NM_001159673
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr10_+_11206928 6.059 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr6_-_86352564 5.912 NM_001159674
NM_001253771
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr14_+_60712469 5.711 NM_177952
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr10_+_11047253 5.664 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr19_-_2051222 5.617 NM_017572
NM_199054
MKNK2

MAP kinase interacting serine/threonine kinase 2

chr3_-_24536176 5.613 NM_000461
NM_001128176
NM_001128177
NM_001252634
THRB



thyroid hormone receptor, beta



chr4_+_57775064 5.569 NM_001193508
REST
RE1-silencing transcription factor
chr15_+_64791618 5.539 NM_015042
ZNF609
zinc finger protein 609
chr19_-_47617008 5.399 NM_015168
ZC3H4
zinc finger CCCH-type containing 4
chr14_+_64319607 5.391 NM_015180
NM_182914
SYNE2

spectrin repeat containing, nuclear envelope 2

chr4_-_122744978 5.382 NM_001237
CCNA2
cyclin A2
chr3_-_168864066 5.056 NM_001105077
NM_001163999
NM_005241
MECOM


MDS1 and EVI1 complex locus


chr14_+_64680858 5.038 NM_182913
SYNE2
spectrin repeat containing, nuclear envelope 2
chr12_-_24715349 4.871 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr6_+_72596648 4.853 NM_014989
RIMS1
regulating synaptic membrane exocytosis 1
chr12_-_109125289 4.778 NM_014325
CORO1C
coronin, actin binding protein, 1C
chr6_+_89790412 4.762 NM_006813
PNRC1
proline-rich nuclear receptor coactivator 1
chr2_-_148779172 4.750 NM_181742
ORC4
origin recognition complex, subunit 4
chr6_-_86351156 4.678 NM_001159675
NM_001159676
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr15_+_85923739 4.643 NM_006738
NM_007200
AKAP13

A kinase (PRKA) anchor protein 13

chr15_+_57511616 4.606 NM_207040
TCF12
transcription factor 12
chr11_+_9596233 4.580 NM_001143976
WEE1
WEE1 homolog (S. pombe)
chr3_-_168865521 4.562 NM_001164000
MECOM
MDS1 and EVI1 complex locus
chr6_+_143929316 4.547 NM_001100166
NM_014721
PHACTR2

phosphatase and actin regulator 2

chr5_-_59783885 4.511 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_-_64014407 4.456 NM_138689
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr6_-_109703703 4.452 NM_001142401
NM_001142402
NM_001142403
NM_001142404
NM_006016
CD164




CD164 molecule, sialomucin




chr15_+_89631380 4.429 NM_007011
NM_152924
ABHD2

abhydrolase domain containing 2

chr3_-_45017600 4.322 NM_001135179
NM_016598
ZDHHC3

zinc finger, DHHC-type containing 3

chr3_+_151985828 4.312 NM_021038
NM_207292
MBNL1

muscleblind-like (Drosophila)

chr3_+_152017193 4.169 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
MBNL1




muscleblind-like (Drosophila)




chr9_+_110045516 4.155 NM_002874
RAD23B
RAD23 homolog B (S. cerevisiae)
chr3_-_128212027 4.115 NM_032638
GATA2
GATA binding protein 2
chr3_-_168864325 4.093 NM_001105078
MECOM
MDS1 and EVI1 complex locus
chr3_-_128207366 4.074 NM_001145661
GATA2
GATA binding protein 2
chr16_-_87525317 3.999 NM_015144
ZCCHC14
zinc finger, CCHC domain containing 14
chr3_-_125094003 3.981 NM_021964
ZNF148
zinc finger protein 148
chr7_-_138665853 3.978 NM_001164665
NM_020910
KIAA1549

KIAA1549

chr15_+_86220267 3.974 NM_144767
AKAP13
A kinase (PRKA) anchor protein 13
chr14_+_55518313 3.937 NM_144578
MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr16_+_69958900 3.913 NM_199424
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr3_+_43328001 3.853 NM_001100594
NM_017719
SNRK

SNF related kinase

chr11_-_86666211 3.852 NM_012193
FZD4
frizzled family receptor 4
chr22_+_39101806 3.852 NM_004286
GTPBP1
GTP binding protein 1
chr1_-_154943001 3.828 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr21_-_40033617 3.822 NM_001243432
NM_001136154
NM_004449
ERG


v-ets erythroblastosis virus E26 oncogene homolog (avian)


chr10_+_11059854 3.775 NM_006561
CELF2
CUGBP, Elav-like family member 2
chr5_+_65440662 3.670 NM_139168
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr7_+_155089483 3.633 NM_005542
NM_198336
NM_198337
INSIG1


insulin induced gene 1


chr5_+_65440004 3.632 NM_001077199
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chrX_+_129139163 3.568 NM_021946
BCORL1
BCL6 corepressor-like 1
chr2_-_161350304 3.553 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr3_-_38691118 3.546 NM_000335
NM_001099404
NM_001099405
NM_198056
NM_001160160
NM_001160161
SCN5A





sodium channel, voltage-gated, type V, alpha subunit





chr5_-_14871555 3.518 NM_054027
ANKH
ankylosis, progressive homolog (mouse)
chr10_-_14372807 3.507 NM_018027
FRMD4A
FERM domain containing 4A
chr6_+_152011630 3.450 NM_001122742
ESR1
estrogen receptor 1
chr12_+_88536045 3.381 NM_181783
TMTC3
transmembrane and tetratricopeptide repeat containing 3
chr7_+_12726910 3.370 NM_001195396
NM_005738
ARL4A

ADP-ribosylation factor-like 4A

chr10_+_105727469 3.290 NM_014720
SLK
STE20-like kinase
chr12_-_23737507 3.274 NM_178010
SOX5
SRY (sex determining region Y)-box 5
chr15_+_57210823 3.270 NM_003205
NM_207036
NM_207037
NM_207038
TCF12



transcription factor 12



chr5_-_58882274 3.211 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr22_-_41842853 3.207 NM_016272
TOB2
transducer of ERBB2, 2
chr21_+_44394634 3.169 NM_004571
PKNOX1
PBX/knotted 1 homeobox 1
chr1_-_212004113 3.161 NM_014873
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr6_+_152126807 3.143 NM_001122741
ESR1
estrogen receptor 1
chr8_-_55014367 3.083 NM_006330
LYPLA1
lysophospholipase I
chr3_-_18466759 3.026 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr11_-_83984230 3.001 NM_001142700
DLG2
discs, large homolog 2 (Drosophila)
chr3_-_114790221 2.982 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr9_-_127905715 2.942 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chr6_+_152128453 2.900 NM_001122740
ESR1
estrogen receptor 1
chr10_-_931694 2.876 NM_015155
LARP4B
La ribonucleoprotein domain family, member 4B
chr2_-_70994846 2.869 NM_001185054
ADD2
adducin 2 (beta)
chr17_+_80477564 2.795 NM_004514
FOXK2
forkhead box K2
chr5_+_142150291 2.779 NM_001135608
NM_015071
ARHGAP26

Rho GTPase activating protein 26

chr3_-_114478117 2.778 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr8_+_61591239 2.758 NM_017780
CHD7
chromodomain helicase DNA binding protein 7
chr10_+_102505337 2.752 NM_000278
NM_003987
NM_003988
NM_003989
NM_003990
PAX2




paired box 2




chr7_+_12726413 2.700 NM_001037164
NM_212460
ARL4A

ADP-ribosylation factor-like 4A

chr21_-_39870303 2.696 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chrX_+_49832214 2.686 NM_000084
CLCN5
chloride channel 5
chr8_-_72268720 2.684 NM_172058
NM_172059
NM_172060
EYA1


eyes absent homolog 1 (Drosophila)


chr1_-_179112178 2.666 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr3_+_14989076 2.660 NM_003298
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr15_+_52043738 2.658 NM_001142885
NM_014548
TMOD2

tropomodulin 2 (neuronal)

chr21_+_45285101 2.646 NM_020132
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr11_-_30038487 2.603 NM_002233
KCNA4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr5_+_50678957 2.558 NM_002202
ISL1
ISL LIM homeobox 1
chr2_+_64681270 2.549 NM_014181
LGALSL
lectin, galactoside-binding-like
chr5_-_58571916 2.543 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_179198814 2.422 NM_001136001
NM_001168236
NM_001168237
NM_001168238
NM_007314
ABL2




v-abl Abelson murine leukemia viral oncogene homolog 2




chr14_+_32798478 2.401 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr7_+_21467572 2.374 NM_003112
SP4
Sp4 transcription factor
chr2_-_20251788 2.374 NM_014713
LAPTM4A
lysosomal protein transmembrane 4 alpha
chr6_-_86352982 2.357 NM_001159677
NM_006372
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr20_-_8000370 2.350 NM_021156
TMX4
thioredoxin-related transmembrane protein 4
chr5_-_59189620 2.344 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_+_26205490 2.340 NM_001164746
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chrX_+_122993536 2.295 NM_001204401
NM_001167
XIAP

X-linked inhibitor of apoptosis

chr8_+_23101149 2.277 NM_152272
CHMP7
charged multivesicular body protein 7
chr11_+_9595183 2.247 NM_003390
WEE1
WEE1 homolog (S. pombe)
chr15_+_91411884 2.238 NM_002569
FURIN
furin (paired basic amino acid cleaving enzyme)
chr2_-_69614321 2.209 NM_001244710
NM_002056
GFPT1

glutamine--fructose-6-phosphate transaminase 1

chr9_-_123555654 2.200 NM_012164
FBXW2
F-box and WD repeat domain containing 2
chr5_-_132299263 2.196 NM_014423
AFF4
AF4/FMR2 family, member 4
chr14_-_55878537 2.194 NM_014924
ATG14
ATG14 autophagy related 14 homolog (S. cerevisiae)
chr9_+_137218313 2.188 NM_002957
RXRA
retinoid X receptor, alpha
chr3_-_114343052 2.185 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr1_+_244216506 2.176 NM_006352
ZNF238
zinc finger protein 238
chr6_+_143999058 2.172 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chr22_-_37882214 2.164 NM_001166343
NM_002405
MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr3_-_114102488 2.152 NM_001164342
ZBTB20
zinc finger and BTB domain containing 20
chr11_-_47788839 2.127 NM_015308
FNBP4
formin binding protein 4
chr10_-_99258365 2.114 NM_022362
MMS19
MMS19 nucleotide excision repair homolog (S. cerevisiae)
chr6_+_73076431 2.106 NM_001168411
RIMS1
regulating synaptic membrane exocytosis 1
chr2_+_45169036 2.102 NM_005413
SIX3
SIX homeobox 3
chr4_+_75858205 2.099 NM_015393
PARM1
prostate androgen-regulated mucin-like protein 1
chr6_+_167412791 2.093 NM_007045
NM_194429
FGFR1OP

FGFR1 oncogene partner

chr3_-_114866090 2.086 NM_015642
ZBTB20
zinc finger and BTB domain containing 20
chr2_-_148778262 2.073 NM_001190882
NM_001190879
NM_002552
NM_001190881
NM_181741
ORC4




origin recognition complex, subunit 4




chr12_+_94542239 2.033 NM_005761
PLXNC1
plexin C1
chr1_+_181452685 2.015 NM_000721
NM_001205293
NM_001205294
CACNA1E


calcium channel, voltage-dependent, R type, alpha 1E subunit


chr14_+_73525187 2.008 NM_021239
RBM25
RNA binding motif protein 25
chr11_-_83393436 2.008 NM_001142702
DLG2
discs, large homolog 2 (Drosophila)
chr3_-_33481862 1.990 NM_001128160
NM_014517
UBP1

upstream binding protein 1 (LBP-1a)

chr2_+_198380294 1.961 NM_199482
MOB4
MOB family member 4, phocein
chr3_-_119812973 1.910 NM_001146156
NM_002093
GSK3B

glycogen synthase kinase 3 beta

chr17_-_18266691 1.863 NM_004169
NM_148918
SHMT1

serine hydroxymethyltransferase 1 (soluble)

chr8_+_30241943 1.855 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr1_+_33283042 1.854 NM_001017406
NM_022753
S100PBP

S100P binding protein

chr3_+_30647901 1.851 NM_001024847
NM_003242
TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

chr20_-_48729664 1.815 NM_001032288
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr22_+_31518923 1.805 NM_001002837
INPP5J
inositol polyphosphate-5-phosphatase J
chr14_-_91976630 1.793 NM_032560
SMEK1
SMEK homolog 1, suppressor of mek1 (Dictyostelium)
chr3_-_18480203 1.745 NM_001131010
SATB1
SATB homeobox 1
chr2_-_208634051 1.732 NM_003468
FZD5
frizzled family receptor 5
chr4_-_23891608 1.725 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr2_+_166428845 1.719 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr3_-_114343791 1.607 NM_001164346
ZBTB20
zinc finger and BTB domain containing 20
chr11_-_84634437 1.605 NM_001364
DLG2
discs, large homolog 2 (Drosophila)
chr11_-_85338313 1.594 NM_001142699
DLG2
discs, large homolog 2 (Drosophila)
chr6_+_72926144 1.573 NM_001168409
RIMS1
regulating synaptic membrane exocytosis 1
chr3_-_33481877 1.573 NM_001128161
UBP1
upstream binding protein 1 (LBP-1a)
chr2_+_166326156 1.565 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chr12_+_26126687 1.535 NM_001164747
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr10_-_94050799 1.534 NM_014912
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr5_-_59064437 1.511 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_-_53994783 1.418 NM_001130059
ATF7
activating transcription factor 7
chr7_-_129592711 1.399 NM_001202498
UBE2H
ubiquitin-conjugating enzyme E2H
chr14_+_60715950 1.365 NM_021003
NM_177951
PPM1A

protein phosphatase, Mg2+/Mn2+ dependent, 1A

chr6_+_152128685 1.353 NM_000125
ESR1
estrogen receptor 1
chr21_+_45345278 1.303 NM_001037553
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr20_-_48732479 1.301 NM_022442
NM_021988
NM_199144
UBE2V1


ubiquitin-conjugating enzyme E2 variant 1


chr15_+_72766665 1.287 NM_005744
ARIH1
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
chr17_+_61086897 1.244 NM_025185
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr3_+_69812961 1.241 NM_006722
MITF
microphthalmia-associated transcription factor
chr1_+_28764660 1.203 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr15_+_49715374 1.196 NM_002009
FGF7
fibroblast growth factor 7
chr4_+_3768295 1.195 NM_000683
ADRA2C
adrenergic, alpha-2C-, receptor
chr11_+_86748870 1.187 NM_001168724
NM_022918
TMEM135

transmembrane protein 135

chr6_+_72926462 1.155 NM_001168410
RIMS1
regulating synaptic membrane exocytosis 1
chr22_+_30279064 1.149 NM_021090
NM_153050
NM_153051
MTMR3


myotubularin related protein 3


chr14_+_102276125 1.146 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr11_-_84028379 1.114 NM_001206769
DLG2
discs, large homolog 2 (Drosophila)
chr4_+_1894508 1.110 NM_007331
NM_133330
NM_133331
NM_133335
WHSC1



Wolf-Hirschhorn syndrome candidate 1



chr1_+_199996729 1.106 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2

chr3_+_185080835 1.105 NM_004721
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr12_-_12419702 1.093 NM_002336
LRP6
low density lipoprotein receptor-related protein 6
chr1_-_115632047 1.090 NM_005725
TSPAN2
tetraspanin 2
chr14_+_102228134 1.081 NM_001161725
NM_001161726
PPP2R5C

protein phosphatase 2, regulatory subunit B', gamma

chr2_-_65593866 1.043 NM_001128210
SPRED2
sprouty-related, EVH1 domain containing 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.04 5.06e-09 GO:0019222 regulation of metabolic process
2.17 5.12e-09 GO:0060255 regulation of macromolecule metabolic process
2.12 5.88e-09 GO:0031323 regulation of cellular metabolic process
3.57 2.31e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.09 2.45e-08 GO:0080090 regulation of primary metabolic process
1.54 1.76e-06 GO:0050789 regulation of biological process
3.57 4.98e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.28 5.01e-06 GO:0051252 regulation of RNA metabolic process
1.55 6.26e-06 GO:0050794 regulation of cellular process
3.88 6.96e-06 GO:0045893 positive regulation of transcription, DNA-dependent
3.72 7.90e-06 GO:0010628 positive regulation of gene expression
3.46 9.61e-06 GO:0051173 positive regulation of nitrogen compound metabolic process
4.93 1.17e-05 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
2.11 1.18e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.87 1.22e-05 GO:0032502 developmental process
1.48 1.26e-05 GO:0065007 biological regulation
3.50 1.43e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
2.13 1.75e-05 GO:0010468 regulation of gene expression
2.17 1.77e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
4.25 2.60e-05 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
3.61 2.80e-05 GO:0051254 positive regulation of RNA metabolic process
2.23 3.05e-05 GO:0006355 regulation of transcription, DNA-dependent
2.05 3.52e-05 GO:0051171 regulation of nitrogen compound metabolic process
3.23 4.26e-05 GO:0031328 positive regulation of cellular biosynthetic process
2.12 4.38e-05 GO:0010556 regulation of macromolecule biosynthetic process
3.17 6.10e-05 GO:0009891 positive regulation of biosynthetic process
2.69 6.93e-05 GO:0009893 positive regulation of metabolic process
2.04 8.01e-05 GO:0031326 regulation of cellular biosynthetic process
2.77 9.37e-05 GO:0010604 positive regulation of macromolecule metabolic process
3.09 1.07e-04 GO:0006351 transcription, DNA-dependent
2.02 1.18e-04 GO:0009889 regulation of biosynthetic process
1.86 1.21e-04 GO:0007275 multicellular organismal development
1.71 1.52e-04 GO:0044260 cellular macromolecule metabolic process
4.16 1.70e-04 GO:0032583 regulation of gene-specific transcription
2.69 1.81e-04 GO:0031325 positive regulation of cellular metabolic process
1.95 2.58e-04 GO:0048731 system development
12.22 2.61e-04 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
1.98 3.07e-04 GO:0048518 positive regulation of biological process
2.03 4.12e-04 GO:0048522 positive regulation of cellular process
1.85 7.67e-04 GO:0048856 anatomical structure development
2.79 8.64e-04 GO:0032774 RNA biosynthetic process
2.09 1.22e-03 GO:0048869 cellular developmental process
2.10 1.45e-03 GO:0030154 cell differentiation
2.11 2.99e-03 GO:0048513 organ development
3.22 4.44e-03 GO:0009887 organ morphogenesis
1.56 5.96e-03 GO:0043170 macromolecule metabolic process
1.53 7.10e-03 GO:0032501 multicellular organismal process
2.22 9.00e-03 GO:0009653 anatomical structure morphogenesis
1.94 1.09e-02 GO:0090304 nucleic acid metabolic process
4.31 1.11e-02 GO:0007423 sensory organ development
2.08 1.41e-02 GO:0016070 RNA metabolic process
1.43 2.26e-02 GO:0044237 cellular metabolic process
2.01 2.42e-02 GO:0010467 gene expression
2.94 2.76e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.84 2.79e-02 GO:0031327 negative regulation of cellular biosynthetic process
2.78 3.74e-02 GO:0009890 negative regulation of biosynthetic process
12.81 3.91e-02 GO:0030850 prostate gland development
3.06 4.53e-02 GO:0045892 negative regulation of transcription, DNA-dependent
2.11 4.66e-02 GO:0007399 nervous system development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.60 9.53e-06 GO:0005634 nucleus
2.49 7.52e-05 GO:0005654 nucleoplasm
2.16 1.93e-04 GO:0031981 nuclear lumen
1.30 4.83e-04 GO:0043229 intracellular organelle
1.30 5.47e-04 GO:0043226 organelle
1.96 9.80e-04 GO:0044428 nuclear part
1.23 1.01e-03 GO:0044424 intracellular part
1.32 1.62e-03 GO:0043231 intracellular membrane-bounded organelle
1.32 1.73e-03 GO:0043227 membrane-bounded organelle
1.22 1.81e-03 GO:0005622 intracellular
1.89 2.66e-03 GO:0070013 intracellular organelle lumen
1.85 4.39e-03 GO:0043233 organelle lumen
1.82 6.57e-03 GO:0031974 membrane-enclosed lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
4.20 2.60e-09 GO:0043565 sequence-specific DNA binding
3.47 5.72e-09 GO:0001071 nucleic acid binding transcription factor activity
3.47 5.72e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
16.12 1.08e-07 GO:0004879 ligand-dependent nuclear receptor activity
1.52 5.93e-07 GO:0005515 protein binding
15.37 1.28e-06 GO:0003707 steroid hormone receptor activity
3.02 2.58e-06 GO:0030528 transcription regulator activity
5.61 1.37e-04 GO:0000975 regulatory region DNA binding
5.61 1.37e-04 GO:0001067 regulatory region nucleic acid binding
5.61 1.37e-04 GO:0044212 transcription regulatory region DNA binding
1.23 2.15e-04 GO:0005488 binding
5.39 5.65e-04 GO:0010843 promoter binding
4.24 6.30e-04 GO:0016563 transcription activator activity
1.72 1.54e-03 GO:0003676 nucleic acid binding
1.84 5.64e-03 GO:0003677 DNA binding
4.25 6.26e-03 GO:0003702 RNA polymerase II transcription factor activity
4.75 2.74e-02 GO:0000287 magnesium ion binding
5.16 3.70e-02 GO:0003690 double-stranded DNA binding
3.49 4.15e-02 GO:0016564 transcription repressor activity