Motif ID: GFI1.p2

Z-value: 1.599


Transcription factors associated with GFI1.p2:

Gene SymbolEntrez IDGene Name
GFI1 2672 growth factor independent 1 transcription repressor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GFI1chr1_-_92952429-0.414.4e-10Click!


Activity profile for motif GFI1.p2.

activity profile for motif GFI1.p2


Sorted Z-values histogram for motif GFI1.p2

Sorted Z-values for motif GFI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_172468469 33.767 ECT2
epithelial cell transforming sequence 2 oncogene
chr19_-_14247267 28.288 ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr19_-_14247400 26.128 NM_018154
ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr9_+_91926109 23.486 NM_001827
CKS2
CDC28 protein kinase regulatory subunit 2
chr14_-_55658205 23.014 NM_001146015
NM_014750
DLGAP5

discs, large (Drosophila) homolog-associated protein 5

chr17_-_38574042 22.942 NM_001067
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr12_-_120315074 19.586 NM_001206999
NM_007174
CIT

citron (rho-interacting, serine/threonine kinase 21)

chr12_+_104324157 19.554 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr8_-_25315941 18.777 NM_017634
KCTD9
potassium channel tetramerisation domain containing 9
chrX_-_107334749 18.737 NM_002814
NM_170750
PSMD10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chrX_+_154444700 18.343 NM_003372
VBP1
von Hippel-Lindau binding protein 1
chr12_+_104324192 17.652 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr1_+_62902325 17.468 NM_003368
USP1
ubiquitin specific peptidase 1
chr17_-_76183074 17.451 NM_003258
TK1
thymidine kinase 1, soluble
chr8_-_101964248 16.639 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr8_-_101964247 16.516 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr12_+_104324214 16.437 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr8_-_101964268 16.354 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr8_-_101964236 16.216 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr12_+_104324186 16.037 NM_003299
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr8_-_101964258 15.775 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr16_-_69760354 15.480 NQO1
NAD(P)H dehydrogenase, quinone 1
chr8_-_101964197 15.444 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr1_-_68962679 15.249 DEPDC1
DEP domain containing 1
chr6_-_38670882 15.115 GLO1
glyoxalase I
chr6_-_38670904 14.746 GLO1
glyoxalase I
chr2_+_47630291 14.678 MSH2
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr12_-_102513846 14.552 NUP37
nucleoporin 37kDa
chr6_-_38670922 14.423 NM_006708
GLO1
glyoxalase I
chr2_+_47630190 14.397 MSH2
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chrX_+_119737905 14.352 MCTS1
malignant T cell amplified sequence 1
chr2_+_47630246 14.292 NM_000251
MSH2
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chrX_+_119737984 14.275 MCTS1
malignant T cell amplified sequence 1
chr14_+_54863672 14.274 NM_001130851
NM_005192
CDKN3

cyclin-dependent kinase inhibitor 3

chr12_+_96252770 14.040 SNRPF
small nuclear ribonucleoprotein polypeptide F
chr12_+_64803741 14.014 XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr12_+_96252705 13.834 NM_003095
SNRPF
small nuclear ribonucleoprotein polypeptide F
chr16_+_23690160 13.655 PLK1
polo-like kinase 1
chr16_+_23690212 13.558 PLK1
polo-like kinase 1
chr6_-_38670829 13.045 GLO1
glyoxalase I
chr16_+_23690234 12.773 PLK1
polo-like kinase 1
chrX_-_13835012 12.646 GPM6B
glycoprotein M6B
chr16_+_23690191 12.589 NM_005030
PLK1
polo-like kinase 1
chr16_+_89989686 12.527 NM_006086
TUBB3
tubulin, beta 3 class III
chr20_-_54967221 12.413 NM_003600
NM_198433
NM_198434
NM_198435
NM_198436
NM_198437
AURKA





aurora kinase A





chr16_+_23690190 12.110 PLK1
polo-like kinase 1
chr14_-_64010087 11.925 PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr19_-_55919324 11.846 NM_014501
UBE2S
ubiquitin-conjugating enzyme E2S
chr8_+_73921061 11.709 NM_003218
NM_017489
TERF1

telomeric repeat binding factor (NIMA-interacting) 1

chr17_+_70117168 11.545 SOX9
SRY (sex determining region Y)-box 9
chr2_+_170662044 11.495 SSB
Sjogren syndrome antigen B (autoantigen La)
chr8_-_101964334 11.370 NM_145690
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr17_+_76183397 11.345 NM_001010982
NM_001145526
AFMID

arylformamidase

chr19_-_55918980 11.338 UBE2S
ubiquitin-conjugating enzyme E2S
chr14_-_64009971 11.307 PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr17_+_70117177 11.291 SOX9
SRY (sex determining region Y)-box 9
chr5_+_137514416 11.151 NM_005733
KIF20A
kinesin family member 20A
chr1_-_68962726 11.133 NM_001114120
NM_017779
DEPDC1

DEP domain containing 1

chr16_-_69760367 11.091 NQO1
NAD(P)H dehydrogenase, quinone 1
chr16_-_69760444 11.030 NM_000903
NM_001025433
NM_001025434
NQO1


NAD(P)H dehydrogenase, quinone 1


chr12_+_79258588 10.943 SYT1
synaptotagmin I
chr11_-_10830452 10.770 EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr4_-_176734181 10.738 NM_201591
GPM6A
glycoprotein M6A
chr12_+_49716970 10.726 NM_001100620
NM_005480
TROAP

trophinin associated protein (tastin)

chr5_+_137514753 10.674 KIF20A
kinesin family member 20A
chr8_-_25315791 10.535 KCTD9
potassium channel tetramerisation domain containing 9
chr17_+_45727274 10.533 NM_002265
KPNB1
karyopherin (importin) beta 1
chr15_+_80364902 10.360 NM_001242915
NM_001242916
ZFAND6

zinc finger, AN1-type domain 6

chr1_-_109825767 10.248 NM_001005290
NM_001032291
NM_032636
PSRC1


proline/serine-rich coiled-coil 1


chr7_-_94285477 10.196 NM_001099400
NM_001099401
NM_003919
SGCE


sarcoglycan, epsilon


chr19_+_36606337 10.196 TBCB
tubulin folding cofactor B
chr8_+_26150731 10.063 NM_001177591
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr20_+_30326903 10.058 NM_012112
TPX2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr8_+_42010463 9.947 NM_001134296
NM_006803
AP3M2

adaptor-related protein complex 3, mu 2 subunit

chr14_+_65878579 9.919 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr1_-_109825683 9.917 PSRC1
proline/serine-rich coiled-coil 1
chr12_-_2986299 9.877 NM_001243088
NM_001243089
NM_021953
NM_202002
NM_202003
FOXM1




forkhead box M1




chr12_-_50419160 9.852 NM_001126103
NM_001126104
NM_013277
RACGAP1


Rac GTPase activating protein 1


chr2_+_63815742 9.840 NM_005917
MDH1
malate dehydrogenase 1, NAD (soluble)
chr7_+_94285676 9.835 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chr2_+_63816092 9.832 MDH1
malate dehydrogenase 1, NAD (soluble)
chr14_-_64010063 9.822 NM_006246
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr7_-_94285426 9.790 SGCE
sarcoglycan, epsilon
chr15_+_77223942 9.763 NM_002902
RCN2
reticulocalbin 2, EF-hand calcium binding domain
chr2_+_63816143 9.730 NM_001199111
NM_001199112
MDH1

malate dehydrogenase 1, NAD (soluble)

chr11_+_63953630 9.565 STIP1
stress-induced-phosphoprotein 1
chr7_-_94285372 9.534 SGCE
sarcoglycan, epsilon
chr8_+_26435339 9.476 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chrX_+_102631267 9.445 NM_206915
NM_206917
NGFRAP1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr17_-_5322870 9.438 NUP88
nucleoporin 88kDa
chr20_+_44441334 9.430 UBE2C
ubiquitin-conjugating enzyme E2C
chr17_-_73150769 9.312 NM_001002032
NM_001002033
NM_016185
HN1


hematological and neurological expressed 1


chr17_+_70117154 9.289 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr5_-_150138081 9.280 NM_001135644
DCTN4
dynactin 4 (p62)
chr11_+_43702142 9.232 NM_016142
HSD17B12
hydroxysteroid (17-beta) dehydrogenase 12
chr7_+_94285736 9.229 PEG10
paternally expressed 10
chr12_+_27175482 9.220 NM_004264
MED21
mediator complex subunit 21
chr12_-_49582800 9.211 NM_006009
TUBA1A
tubulin, alpha 1a
chr11_-_134093869 9.073 NCAPD3
non-SMC condensin II complex, subunit D3
chr2_-_96874507 8.974 STARD7
StAR-related lipid transfer (START) domain containing 7
chr9_-_35103089 8.972 STOML2
stomatin (EPB72)-like 2
chr5_-_133561745 8.955 PPP2CA
protein phosphatase 2, catalytic subunit, alpha isozyme
chr5_+_44808967 8.943 NM_016640
MRPS30
mitochondrial ribosomal protein S30
chr17_+_66031814 8.903 NM_002266
KPNA2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr19_-_22966972 8.878 NM_001080409
ZNF99
zinc finger protein 99
chr5_+_31532372 8.847 NM_018356
C5orf22
chromosome 5 open reading frame 22
chrX_-_102941582 8.845 NM_001142418
NM_001142423
NM_001142424
NM_001142425
NM_001142426
NM_001142429
NM_001142430
NM_012286
MORF4L2







mortality factor 4 like 2







chr2_-_96873938 8.827 STARD7
StAR-related lipid transfer (START) domain containing 7
chr10_-_58121011 8.802 ZWINT
ZW10 interactor
chr16_-_18812691 8.753 NM_015161
ARL6IP1
ADP-ribosylation factor-like 6 interacting protein 1
chr10_-_58121019 8.735 NM_001005413
NM_007057
NM_032997
ZWINT


ZW10 interactor


chr14_+_52456322 8.714 C14orf166
chromosome 14 open reading frame 166
chr20_+_44441247 8.627 NM_007019
NM_181799
NM_181800
NM_181802
NM_181803
UBE2C




ubiquitin-conjugating enzyme E2C




chrX_+_102631408 8.614 NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr11_-_10830299 8.581 EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr5_-_133561551 8.569 PPP2CA
protein phosphatase 2, catalytic subunit, alpha isozyme
chr6_+_80714321 8.539 NM_001166691
NM_003318
TTK

TTK protein kinase

chr22_+_19467467 8.419 CDC45
cell division cycle 45 homolog (S. cerevisiae)
chr6_-_38670871 8.419 GLO1
glyoxalase I
chr6_-_38670915 8.408 GLO1
glyoxalase I
chr5_+_179132676 8.401 CANX
calnexin
chr17_+_66031885 8.339 KPNA2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr7_+_128379452 8.333 CALU
calumenin
chr20_-_48770302 8.333 NM_001162505
NM_199129
NM_199203
TMEM189

TMEM189-UBE2V1
transmembrane protein 189

TMEM189-UBE2V1 readthrough
chr9_-_35103048 8.312 STOML2
stomatin (EPB72)-like 2
chr11_-_134093826 8.292 NCAPD3
non-SMC condensin II complex, subunit D3
chr9_-_95055966 8.274 NM_013417
IARS
isoleucyl-tRNA synthetase
chr1_+_120254418 8.243 NM_006623
PHGDH
phosphoglycerate dehydrogenase
chr9_-_95055986 8.242 IARS
isoleucyl-tRNA synthetase
chr1_+_62902653 8.203 USP1
ubiquitin specific peptidase 1
chr7_+_128379400 8.191 CALU
calumenin
chr4_+_83956238 8.165 NM_016129
COPS4
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
chr1_+_62902735 8.159 USP1
ubiquitin specific peptidase 1
chr9_-_35103144 8.145 NM_013442
STOML2
stomatin (EPB72)-like 2
chr7_+_128379428 8.136 CALU
calumenin
chr11_+_63953586 8.097 NM_006819
STIP1
stress-induced-phosphoprotein 1
chr11_-_119293848 8.085 THY1
Thy-1 cell surface antigen
chr1_+_62902708 8.022 USP1
ubiquitin specific peptidase 1
chr22_+_19467413 8.018 NM_001178010
NM_001178011
NM_003504
CDC45


cell division cycle 45 homolog (S. cerevisiae)


chr17_+_6347733 8.016 NM_001195228
NM_019013
FAM64A

family with sequence similarity 64, member A

chr12_-_2986095 8.004 FOXM1
forkhead box M1
chr9_+_131446105 7.998 SET
SET nuclear oncogene
chr8_-_124408665 7.961 ATAD2
ATPase family, AAA domain containing 2
chr7_+_94285620 7.941 NM_001040152
NM_001184961
NM_001184962
NM_015068
PEG10



paternally expressed 10



chr11_-_10830581 7.939 NM_001042559
NM_001418
EIF4G2

eukaryotic translation initiation factor 4 gamma, 2

chr17_+_34842472 7.907 NM_004773
ZNHIT3
zinc finger, HIT-type containing 3
chr1_-_31769599 7.846 NM_004814
SNRNP40
small nuclear ribonucleoprotein 40kDa (U5)
chr15_-_83876769 7.833 HDGFRP3
hepatoma-derived growth factor, related protein 3
chr20_+_44441671 7.806 NM_181801
UBE2C
ubiquitin-conjugating enzyme E2C
chr6_+_123100645 7.798 NM_001446
FABP7
fatty acid binding protein 7, brain
chr15_-_42749710 7.788 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr1_-_95392449 7.772 CNN3
calponin 3, acidic
chr11_-_71159442 7.749 NM_001163817
NM_001360
DHCR7

7-dehydrocholesterol reductase

chr9_+_36190885 7.706 CLTA
clathrin, light chain A
chr5_-_137878808 7.675 ETF1
eukaryotic translation termination factor 1
chr1_-_150669499 7.648 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr2_-_234763182 7.648 NM_018410
HJURP
Holliday junction recognition protein
chr12_+_6603258 7.636 NCAPD2
non-SMC condensin I complex, subunit D2
chr2_-_234763145 7.634 HJURP
Holliday junction recognition protein
chr7_+_128379395 7.624 CALU
calumenin
chrX_+_119738542 7.531 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chr20_+_47662782 7.527 NM_001316
CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr3_-_145879222 7.510 NM_000935
NM_182943
PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

chr17_-_40075153 7.493 ACLY
ATP citrate lyase
chr10_+_62538250 7.481 CDK1
cyclin-dependent kinase 1
chr5_-_137090037 7.475 NM_006805
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr6_-_18264638 7.439 NM_001134709
NM_003472
DEK

DEK oncogene

chr1_+_214776494 7.437 NM_016343
CENPF
centromere protein F, 350/400kDa (mitosin)
chr12_+_6603291 7.421 NM_014865
NCAPD2
non-SMC condensin I complex, subunit D2
chr3_+_50273745 7.421 GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr19_+_36605887 7.420 NM_001281
TBCB
tubulin folding cofactor B
chr6_+_111135823 7.420 AMD1
adenosylmethionine decarboxylase 1
chr9_+_131445933 7.383 NM_001122821
SET
SET nuclear oncogene
chr11_+_63953666 7.355 STIP1
stress-induced-phosphoprotein 1
chr17_-_5322982 7.351 NM_002532
NUP88
nucleoporin 88kDa
chr8_-_124408688 7.344 NM_014109
ATAD2
ATPase family, AAA domain containing 2
chr12_+_56618104 7.312 NM_024068
OBFC2B
oligonucleotide/oligosaccharide-binding fold containing 2B
chr2_-_96874569 7.306 NM_020151
STARD7
StAR-related lipid transfer (START) domain containing 7
chr4_-_174255454 7.272 NM_001130688
NM_002129
HMGB2

high mobility group box 2

chr16_-_81129882 7.269 NM_004483
GCSH
glycine cleavage system protein H (aminomethyl carrier)
chr8_-_124408458 7.265 ATAD2
ATPase family, AAA domain containing 2
chrX_+_119737743 7.261 NM_014060
MCTS1
malignant T cell amplified sequence 1
chr12_+_56618150 7.176 OBFC2B
oligonucleotide/oligosaccharide-binding fold containing 2B
chr5_-_31532164 7.173 NM_001100412
NM_013235
DROSHA

drosha, ribonuclease type III

chr6_+_33359620 7.168 KIFC1
kinesin family member C1
chr8_+_66556887 7.162 NM_001145839
NM_014637
MTFR1

mitochondrial fission regulator 1

chr12_+_79258517 7.155 SYT1
synaptotagmin I
chrX_-_37706816 7.154 NM_006520
DYNLT3
dynein, light chain, Tctex-type 3
chr1_-_33282844 7.118 YARS
tyrosyl-tRNA synthetase
chr6_+_33359604 7.084 KIFC1
kinesin family member C1
chrX_+_48380163 7.071 NM_006579
EBP
emopamil binding protein (sterol isomerase)
chr2_-_47403652 7.053 CALM2
calmodulin 2 (phosphorylase kinase, delta)
chr1_-_33283632 7.031 NM_003680
YARS
tyrosyl-tRNA synthetase
chr17_+_45727558 7.020 KPNB1
karyopherin (importin) beta 1
chrX_-_102319080 6.986 BEX1
brain expressed, X-linked 1
chr5_+_179125977 6.977 CANX
calnexin
chr4_-_76598611 6.963 NM_203504
NM_203505
G3BP2

GTPase activating protein (SH3 domain) binding protein 2

chr14_-_105487413 6.942 CDCA4
cell division cycle associated 4
chr2_+_9346909 6.904 ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr4_+_166248816 6.890 NM_001017369
NM_006745
MSMO1

methylsterol monooxygenase 1


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.23 4.52e-26 GO:0009987 cellular process
2.31 5.66e-21 GO:0007049 cell cycle
1.62 4.29e-19 GO:0034641 cellular nitrogen compound metabolic process
1.67 4.21e-18 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.59 5.36e-18 GO:0006807 nitrogen compound metabolic process
2.53 9.20e-18 GO:0022403 cell cycle phase
2.68 1.30e-17 GO:0000278 mitotic cell cycle
2.37 2.83e-17 GO:0022402 cell cycle process
1.72 6.17e-16 GO:0090304 nucleic acid metabolic process
1.64 2.00e-15 GO:0071842 cellular component organization at cellular level
1.35 2.02e-15 GO:0044237 cellular metabolic process
1.44 9.15e-15 GO:0044260 cellular macromolecule metabolic process
1.60 2.52e-14 GO:0071841 cellular component organization or biogenesis at cellular level
3.48 1.08e-12 GO:0000075 cell cycle checkpoint
3.41 1.44e-12 GO:0071156 regulation of cell cycle arrest
1.49 1.72e-12 GO:0016043 cellular component organization
1.30 5.07e-12 GO:0044238 primary metabolic process
1.47 7.39e-12 GO:0071840 cellular component organization or biogenesis
2.59 1.92e-11 GO:0000279 M phase
1.27 3.90e-11 GO:0008152 metabolic process
1.73 7.21e-11 GO:0006996 organelle organization
2.74 1.03e-10 GO:0010564 regulation of cell cycle process
2.86 1.30e-10 GO:0051325 interphase
2.86 2.00e-10 GO:0051329 interphase of mitotic cell cycle
2.28 2.11e-10 GO:0006259 DNA metabolic process
1.34 1.03e-09 GO:0043170 macromolecule metabolic process
2.06 2.21e-09 GO:0071844 cellular component assembly at cellular level
2.77 2.38e-09 GO:0000087 M phase of mitotic cell cycle
2.51 2.43e-08 GO:0034622 cellular macromolecular complex assembly
1.21 7.23e-08 GO:0065007 biological regulation
2.65 8.23e-08 GO:0000280 nuclear division
2.65 8.23e-08 GO:0007067 mitosis
2.61 9.55e-08 GO:0048285 organelle fission
2.06 2.06e-07 GO:0051726 regulation of cell cycle
1.89 3.00e-07 GO:0033554 cellular response to stress
1.22 4.20e-07 GO:0050789 regulation of biological process
1.22 5.68e-07 GO:0050794 regulation of cellular process
2.13 7.83e-07 GO:0006974 response to DNA damage stimulus
1.75 1.16e-06 GO:0022607 cellular component assembly
2.38 1.38e-06 GO:0051301 cell division
1.56 1.88e-06 GO:0016070 RNA metabolic process
1.99 2.67e-06 GO:0051276 chromosome organization
1.43 4.45e-06 GO:0009058 biosynthetic process
3.18 4.95e-06 GO:0000082 G1/S transition of mitotic cell cycle
1.44 5.99e-06 GO:0044249 cellular biosynthetic process
1.31 6.80e-06 GO:0051716 cellular response to stimulus
2.09 7.79e-06 GO:0034621 cellular macromolecular complex subunit organization
1.65 1.55e-05 GO:0044085 cellular component biogenesis
1.49 3.09e-05 GO:0010467 gene expression
3.35 4.48e-05 GO:0000084 S phase of mitotic cell cycle
2.76 5.51e-05 GO:0006260 DNA replication
3.29 6.82e-05 GO:0051320 S phase
2.23 6.98e-05 GO:0006281 DNA repair
1.51 7.05e-05 GO:0034645 cellular macromolecule biosynthetic process
2.31 7.61e-05 GO:0008380 RNA splicing
1.50 9.71e-05 GO:0009059 macromolecule biosynthetic process
1.82 1.13e-04 GO:0065003 macromolecular complex assembly
1.92 2.44e-04 GO:0016071 mRNA metabolic process
1.55 5.59e-04 GO:0051641 cellular localization
1.59 8.63e-04 GO:0051246 regulation of protein metabolic process
1.30 1.12e-03 GO:0060255 regulation of macromolecule metabolic process
1.57 1.72e-03 GO:0051649 establishment of localization in cell
3.44 2.04e-03 GO:0000216 M/G1 transition of mitotic cell cycle
1.48 2.24e-03 GO:0007399 nervous system development
2.59 3.19e-03 GO:0043623 cellular protein complex assembly
2.42 3.28e-03 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.42 3.28e-03 GO:0000398 nuclear mRNA splicing, via spliceosome
2.81 3.37e-03 GO:0007093 mitotic cell cycle checkpoint
1.98 3.39e-03 GO:0006397 mRNA processing
2.21 3.58e-03 GO:0007017 microtubule-based process
1.26 4.15e-03 GO:0019222 regulation of metabolic process
4.10 4.33e-03 GO:0007051 spindle organization
1.66 4.79e-03 GO:0046907 intracellular transport
1.62 4.93e-03 GO:0045184 establishment of protein localization
2.17 5.45e-03 GO:0007346 regulation of mitotic cell cycle
2.68 5.57e-03 GO:0006310 DNA recombination
1.63 5.71e-03 GO:0043933 macromolecular complex subunit organization
2.36 6.07e-03 GO:0000375 RNA splicing, via transesterification reactions
1.54 7.29e-03 GO:0008104 protein localization
1.33 7.29e-03 GO:0044267 cellular protein metabolic process
1.55 7.48e-03 GO:0042981 regulation of apoptosis
4.36 1.01e-02 GO:0030071 regulation of mitotic metaphase/anaphase transition
1.54 1.11e-02 GO:0043067 regulation of programmed cell death
1.35 1.19e-02 GO:0048523 negative regulation of cellular process
1.60 1.30e-02 GO:0015031 protein transport
3.18 1.32e-02 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.26 1.43e-02 GO:0080090 regulation of primary metabolic process
1.88 1.53e-02 GO:0043086 negative regulation of catalytic activity
1.33 1.62e-02 GO:0048519 negative regulation of biological process
1.70 2.01e-02 GO:0009057 macromolecule catabolic process
1.51 2.25e-02 GO:0010941 regulation of cell death
2.73 2.29e-02 GO:0031570 DNA integrity checkpoint
1.87 2.32e-02 GO:0051247 positive regulation of protein metabolic process
2.44 2.51e-02 GO:0010498 proteasomal protein catabolic process
2.44 2.51e-02 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.75 2.67e-02 GO:0044265 cellular macromolecule catabolic process
2.76 3.02e-02 GO:0000086 G2/M transition of mitotic cell cycle
3.96 3.30e-02 GO:0000819 sister chromatid segregation
2.16 3.31e-02 GO:0051129 negative regulation of cellular component organization
1.74 3.50e-02 GO:0044092 negative regulation of molecular function
1.95 3.99e-02 GO:0033043 regulation of organelle organization
1.66 4.06e-02 GO:0006396 RNA processing
1.44 4.60e-02 GO:0033036 macromolecule localization
1.85 4.76e-02 GO:0006886 intracellular protein transport

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.23 5.84e-29 GO:0044424 intracellular part
1.22 2.70e-28 GO:0005622 intracellular
1.26 1.32e-24 GO:0043229 intracellular organelle
1.26 2.79e-24 GO:0043226 organelle
1.31 1.02e-23 GO:0005737 cytoplasm
1.29 1.41e-23 GO:0043227 membrane-bounded organelle
1.29 1.75e-23 GO:0043231 intracellular membrane-bounded organelle
1.40 3.97e-19 GO:0005634 nucleus
1.36 5.83e-17 GO:0044444 cytoplasmic part
1.38 1.69e-16 GO:0044446 intracellular organelle part
1.37 3.02e-16 GO:0044422 organelle part
1.68 1.48e-14 GO:0005829 cytosol
1.64 3.88e-13 GO:0044428 nuclear part
1.46 7.96e-13 GO:0032991 macromolecular complex
1.49 9.41e-12 GO:0043234 protein complex
1.55 6.33e-11 GO:0031974 membrane-enclosed lumen
1.60 1.17e-09 GO:0031981 nuclear lumen
1.53 2.00e-09 GO:0070013 intracellular organelle lumen
2.04 3.88e-09 GO:0015630 microtubule cytoskeleton
1.51 5.29e-09 GO:0043233 organelle lumen
1.45 1.39e-08 GO:0043228 non-membrane-bounded organelle
1.45 1.39e-08 GO:0043232 intracellular non-membrane-bounded organelle
1.68 2.59e-08 GO:0005654 nucleoplasm
2.23 3.07e-08 GO:0044427 chromosomal part
2.10 4.68e-08 GO:0005694 chromosome
3.00 1.18e-07 GO:0005819 spindle
1.07 1.77e-07 GO:0005623 cell
1.07 3.14e-07 GO:0044464 cell part
1.55 2.43e-06 GO:0005856 cytoskeleton
1.61 4.58e-05 GO:0044430 cytoskeletal part
2.43 1.33e-04 GO:0000228 nuclear chromosome
2.60 1.51e-04 GO:0044454 nuclear chromosome part
3.50 9.39e-04 GO:0005643 nuclear pore
3.64 1.98e-03 GO:0030496 midbody
2.07 2.02e-03 GO:0005874 microtubule
3.45 2.17e-03 GO:0000922 spindle pole
2.55 2.60e-03 GO:0000775 chromosome, centromeric region
3.05 2.63e-03 GO:0000776 kinetochore
4.47 3.03e-03 GO:0005758 mitochondrial intermembrane space
3.07 4.00e-03 GO:0046930 pore complex
5.96 9.59e-03 GO:0000159 protein phosphatase type 2A complex
4.02 1.02e-02 GO:0031970 organelle envelope lumen
2.05 1.35e-02 GO:0005635 nuclear envelope
2.41 1.53e-02 GO:0000793 condensed chromosome
1.57 2.36e-02 GO:0031967 organelle envelope
7.31 2.60e-02 GO:0005744 mitochondrial inner membrane presequence translocase complex
3.78 4.20e-02 GO:0005876 spindle microtubule
1.54 4.27e-02 GO:0031975 envelope
1.98 4.58e-02 GO:0000785 chromatin

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.39 3.82e-28 GO:0005515 protein binding
1.16 4.72e-15 GO:0005488 binding
1.76 3.65e-05 GO:0019899 enzyme binding
1.69 2.17e-04 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.37 2.23e-04 GO:0000166 nucleotide binding
1.68 2.61e-04 GO:0016817 hydrolase activity, acting on acid anhydrides
1.68 3.39e-04 GO:0016462 pyrophosphatase activity
1.67 8.07e-04 GO:0017111 nucleoside-triphosphatase activity
1.44 9.42e-04 GO:0032559 adenyl ribonucleotide binding
1.45 9.65e-04 GO:0005524 ATP binding
6.70 1.21e-03 GO:0008601 protein phosphatase type 2A regulator activity
1.43 1.30e-03 GO:0030554 adenyl nucleotide binding
1.96 3.19e-03 GO:0016887 ATPase activity
1.37 3.69e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.36 4.50e-03 GO:0032553 ribonucleotide binding
1.36 4.50e-03 GO:0032555 purine ribonucleotide binding
1.36 6.32e-03 GO:0017076 purine nucleotide binding
3.83 2.53e-02 GO:0019888 protein phosphatase regulator activity
1.94 3.28e-02 GO:0042623 ATPase activity, coupled