Motif ID: GLI1..3.p2

Z-value: 1.543


Transcription factors associated with GLI1..3.p2:

Gene SymbolEntrez IDGene Name
GLI1 2735 glioma-associated oncogene homolog 1 (zinc finger protein)
GLI2 2736 GLI-Kruppel family member GLI2
GLI3 2737 GLI-Kruppel family member GLI3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GLI1chr12_+_578539170.561.3e-19Click!
GLI2chr2_+_1215548660.473.3e-13Click!
GLI3chr7_-_422766170.433.9e-11Click!


Activity profile for motif GLI1..3.p2.

activity profile for motif GLI1..3.p2


Sorted Z-values histogram for motif GLI1..3.p2

Sorted Z-values for motif GLI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GLI1..3.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_175792444 27.877 NM_173664
ARL10
ADP-ribosylation factor-like 10
chr12_-_6798419 25.557 ZNF384
zinc finger protein 384
chr12_-_6798619 23.914 NM_001039920
NM_001135734
ZNF384

zinc finger protein 384

chr22_-_19512001 23.526 CLDN5
claudin 5
chr22_-_19511777 20.579 CLDN5
claudin 5
chr22_+_22569155 20.551


chrX_-_106960028 19.076 TSC22D3
TSC22 domain family, member 3
chrX_-_78622711 18.708 ITM2A
integral membrane protein 2A
chr8_+_21916858 17.748 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr16_+_28834407 17.571 NM_007245
NM_145714
NM_148414
NM_148415
NM_148416
ATXN2L




ataxin 2-like




chr8_+_21916685 17.521 NM_001114138
NM_001978
EPB49

erythrocyte membrane protein band 4.9 (dematin)

chr12_-_6798528 17.113 NM_133476
ZNF384
zinc finger protein 384
chr15_-_77712436 16.665 NM_024776
PEAK1
NKF3 kinase family member
chr11_-_72380107 16.206 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr10_+_104503724 15.532 NM_001083913
C10orf26
chromosome 10 open reading frame 26
chr16_+_28834565 15.386 ATXN2L
ataxin 2-like
chr12_-_45269953 14.662 NELL2
NEL-like 2 (chicken)
chr9_-_113800243 14.205 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chrX_+_13671224 14.070 NM_152634
TCEANC
transcription elongation factor A (SII) N-terminal and central domain containing
chr3_-_10067989 13.933 CIDECP
cell death-inducing DFFA-like effector c pseudogene
chr15_+_74421698 13.844 NM_001130136
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr15_+_74421986 13.822 NM_001130137
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr19_+_16435632 13.773 NM_016270
KLF2
Kruppel-like factor 2 (lung)
chrX_-_78623006 13.546 NM_001171581
NM_004867
ITM2A

integral membrane protein 2A

chr19_+_45417576 13.241 APOC1
apolipoprotein C-I
chr12_+_79258517 13.237 SYT1
synaptotagmin I
chr19_+_39833096 13.139 SAMD4B
sterile alpha motif domain containing 4B
chr19_+_45418063 13.124 APOC1
apolipoprotein C-I
chr2_-_136875629 13.034 NM_003467
CXCR4
chemokine (C-X-C motif) receptor 4
chr20_-_39766522 12.960


chr11_+_1892098 12.559 NM_001013254
NM_001013255
LSP1

lymphocyte-specific protein 1

chr16_+_30194925 12.500 CORO1A
coronin, actin binding protein, 1A
chr3_-_38071030 12.460 NM_006225
PLCD1
phospholipase C, delta 1
chr19_+_16435734 12.377 KLF2
Kruppel-like factor 2 (lung)
chr3_+_10028579 12.326 LOC442075
uncharacterized LOC442075
chr11_-_64512265 12.294 NM_001098670
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr20_+_36149606 12.038 NM_005386
NM_181689
NNAT

neuronatin

chr3_+_49591897 11.857 NM_003458
BSN
bassoon (presynaptic cytomatrix protein)
chr19_+_39833099 11.649 NM_018028
SAMD4B
sterile alpha motif domain containing 4B
chr19_-_33793429 11.623 NM_004364
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr7_-_99680358 11.573 ZNF3
zinc finger protein 3
chr12_-_45270071 11.487 NELL2
NEL-like 2 (chicken)
chr12_-_112819755 11.456 NM_001109662
C12orf51
chromosome 12 open reading frame 51
chr1_+_36689996 11.284 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chr4_-_176734181 11.233 NM_201591
GPM6A
glycoprotein M6A
chr4_-_176733901 11.142 GPM6A
glycoprotein M6A
chr5_-_149535138 11.007 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr19_+_33793743 10.998 LOC80054
uncharacterized LOC80054
chr12_-_45270157 10.962 NM_001145108
NM_006159
NELL2

NEL-like 2 (chicken)

chr19_+_3178735 10.950 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chr3_+_45067750 10.927 NM_003278
CLEC3B
C-type lectin domain family 3, member B
chr7_-_100171269 10.841 NM_001168682
SAP25
Sin3A-associated protein, 25kDa
chr14_+_24584009 10.833 DCAF11
DDB1 and CUL4 associated factor 11
chr6_-_32784727 10.709 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr14_+_92789536 10.567 NM_153647
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr5_+_150400132 10.561 GPX3
glutathione peroxidase 3 (plasma)
chr9_-_86571631 10.550 C9orf64
chromosome 9 open reading frame 64
chr6_-_29600668 10.541 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr5_-_43412417 10.496 NM_148672
CCL28
chemokine (C-C motif) ligand 28
chr1_+_36690038 10.444 THRAP3
thyroid hormone receptor associated protein 3
chr22_+_23229959 10.381 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr11_-_64511550 10.191 NM_001098671
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr2_+_149632772 10.145 NM_004522
KIF5C
kinesin family member 5C
chr3_+_10068123 10.061 FANCD2
Fanconi anemia, complementation group D2
chr13_-_41240607 10.027 NM_002015
FOXO1
forkhead box O1
chr3_-_15468981 9.928 NM_152396
METTL6
methyltransferase like 6
chr14_-_24584125 9.784 NRL
neural retina leucine zipper
chr19_-_3869012 9.743 NM_001145640
NM_015174
ZFR2

zinc finger RNA binding protein 2

chr15_+_42867708 9.687 NM_020759
STARD9
StAR-related lipid transfer (START) domain containing 9
chr11_+_576482 9.669 NM_020901
PHRF1
PHD and ring finger domains 1
chr16_+_28834372 9.650 ATXN2L
ataxin 2-like
chr17_+_7388080 9.596


chr6_-_29600859 9.585 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr22_-_39152008 9.548 NM_001199579
NM_015374
SUN2

Sad1 and UNC84 domain containing 2

chr9_-_86571533 9.484 C9orf64
chromosome 9 open reading frame 64
chr12_+_79258588 9.484 SYT1
synaptotagmin I
chr16_+_30194730 9.465 NM_001193333
NM_007074
CORO1A

coronin, actin binding protein, 1A

chr12_-_45270632 9.424 NM_001145107
NELL2
NEL-like 2 (chicken)
chr2_+_203499819 9.406 NM_173511
FAM117B
family with sequence similarity 117, member B
chr6_-_29600959 9.275 NM_001470
NM_021904
GABBR1

gamma-aminobutyric acid (GABA) B receptor, 1

chr20_+_30639981 9.199 NM_001172129
NM_001172130
NM_001172131
NM_001172132
NM_001172133
NM_002110
HCK





hemopoietic cell kinase





chr3_+_10068097 9.152 NM_001018115
NM_033084
FANCD2

Fanconi anemia, complementation group D2

chr1_-_182354649 9.128 GLUL
glutamate-ammonia ligase
chr4_+_166299942 9.047 NM_001873
CPE
carboxypeptidase E
chrX_+_101906293 8.991 NM_001099410
NM_001099411
NM_014710
NM_001184727
GPRASP1



G protein-coupled receptor associated sorting protein 1



chr14_+_24584321 8.893 DCAF11
DDB1 and CUL4 associated factor 11
chr3_+_49449753 8.804 TCTA
T-cell leukemia translocation altered gene
chr6_-_32163299 8.740 NM_022107
GPSM3
G-protein signaling modulator 3
chr14_+_29236882 8.681 FOXG1
forkhead box G1
chr2_+_149633173 8.646


chr21_-_46340776 8.629 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr5_-_157002705 8.574


chr15_+_44580870 8.534 NM_138423
NM_177974
CASC4

cancer susceptibility candidate 4

chr14_-_93651242 8.500 NM_022151
MOAP1
modulator of apoptosis 1
chr4_-_176733413 8.490 GPM6A
glycoprotein M6A
chr6_+_72892371 8.406 RIMS1
regulating synaptic membrane exocytosis 1
chr6_-_46703429 8.379 NM_001168357
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr11_-_66084501 8.325 NM_020404
CD248
CD248 molecule, endosialin
chr1_+_101702561 8.304 S1PR1
sphingosine-1-phosphate receptor 1
chr3_-_195306274 8.304 APOD
apolipoprotein D
chr22_+_19710118 8.112 SEPT5-GP1BB
SEPT5-GP1BB readthrough
chr7_-_994008 8.064 ADAP1
ArfGAP with dual PH domains 1
chrX_-_140271275 7.918 LDOC1
leucine zipper, down-regulated in cancer 1
chr7_-_158622184 7.896 ESYT2
extended synaptotagmin-like protein 2
chr1_+_156123321 7.886 NM_001193300
NM_022367
NM_001193302
SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chr9_-_86571652 7.829 NM_032307
C9orf64
chromosome 9 open reading frame 64
chrX_-_1655999 7.806 NM_178129
P2RY8
CRLF2
purinergic receptor P2Y, G-protein coupled, 8
cytokine receptor-like factor 2
chrY_-_1605999 7.806 NM_178129
P2RY8
CRLF2
purinergic receptor P2Y, G-protein coupled, 8
cytokine receptor-like factor 2
chr12_-_122018858 7.753 NM_032590
KDM2B
lysine (K)-specific demethylase 2B
chr17_+_48172100 7.702 NM_001199898
PDK2
pyruvate dehydrogenase kinase, isozyme 2
chr14_+_24583979 7.700 NM_025230
DCAF11
DDB1 and CUL4 associated factor 11
chr11_+_124609775 7.682 NM_001126181
NM_006176
NRGN

neurogranin (protein kinase C substrate, RC3)

chr19_-_33793441 7.633 CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr7_-_4923246 7.600 NM_018059
RADIL
Ras association and DIL domains
chr11_+_113258512 7.592 NM_178510
ANKK1
ankyrin repeat and kinase domain containing 1
chr17_-_1419770 7.568 INPP5K
inositol polyphosphate-5-phosphatase K
chr14_-_93651182 7.497 MOAP1
modulator of apoptosis 1
chr9_+_123963728 7.436 GSN
gelsolin
chr9_-_98079856 7.383 NM_000136
NM_001243744
FANCC

Fanconi anemia, complementation group C

chr19_+_4969126 7.380 KDM4B
lysine (K)-specific demethylase 4B
chr7_-_108096693 7.372 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr12_-_16757944 7.316 LMO3
LIM domain only 3 (rhombotin-like 2)
chr14_+_24583905 7.255 NM_001163484
DCAF11
DDB1 and CUL4 associated factor 11
chr12_+_112204690 7.238 NM_000690
NM_001204889
ALDH2

aldehyde dehydrogenase 2 family (mitochondrial)

chr17_+_7387773 7.233 POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr17_-_1420177 7.230 NM_001135642
NM_016532
NM_130766
INPP5K


inositol polyphosphate-5-phosphatase K


chr22_-_17690778 7.222 NM_017424
CECR1
cat eye syndrome chromosome region, candidate 1
chr19_-_12721493 7.198 NM_020714
ZNF490
zinc finger protein 490
chr1_-_11986455 7.166 NM_138346
KIAA2013
KIAA2013
chr15_+_78632625 7.145 NM_004378
CRABP1
cellular retinoic acid binding protein 1
chr7_+_73624328 7.134 LAT2
linker for activation of T cells family, member 2
chr14_+_100531745 7.122 NM_016337
EVL
Enah/Vasp-like
chr2_+_149632836 7.079 KIF5C
kinesin family member 5C
chr18_-_60987212 6.977 BCL2
B-cell CLL/lymphoma 2
chr11_-_85376061 6.961 CREBZF
CREB/ATF bZIP transcription factor
chr16_+_2588000 6.930 PDPK1
3-phosphoinositide dependent protein kinase-1
chr11_+_124609841 6.863 NRGN
neurogranin (protein kinase C substrate, RC3)
chr7_+_73624347 6.824 LAT2
linker for activation of T cells family, member 2
chr9_-_98079506 6.823 NM_001243743
FANCC
Fanconi anemia, complementation group C
chr20_-_44455932 6.813 NM_003279
TNNC2
troponin C type 2 (fast)
chr17_+_42219235 6.802 NM_001171251
NM_024032
C17orf53

chromosome 17 open reading frame 53

chr3_-_12200850 6.775 NM_003256
TIMP4
TIMP metallopeptidase inhibitor 4
chr16_+_27325269 6.762 IL4R
interleukin 4 receptor
chr19_-_46318432 6.729 NM_030785
RSPH6A
radial spoke head 6 homolog A (Chlamydomonas)
chr7_-_994259 6.729 NM_006869
ADAP1
ArfGAP with dual PH domains 1
chrX_-_140271293 6.727 NM_012317
LDOC1
leucine zipper, down-regulated in cancer 1
chr7_-_158622202 6.726 NM_020728
ESYT2
extended synaptotagmin-like protein 2
chr19_+_39833132 6.723 SAMD4B
sterile alpha motif domain containing 4B
chr19_-_39108534 6.667 NM_001042600
NM_007181
MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1

chr19_-_49140569 6.654 NM_001352
DBP
D site of albumin promoter (albumin D-box) binding protein
chr11_-_119252267 6.641 USP2
ubiquitin specific peptidase 2
chr5_-_168727715 6.622 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr9_-_100881515 6.567 TRIM14
tripartite motif containing 14
chr10_-_105212022 6.465 CALHM2
calcium homeostasis modulator 2
chr19_+_56652529 6.443 NM_001253792
NM_018337
ZNF444

zinc finger protein 444

chr16_+_27325244 6.441 NM_000418
NM_001008699
IL4R

interleukin 4 receptor

chr21_-_46340821 6.438 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr5_-_95297424 6.419 ELL2
elongation factor, RNA polymerase II, 2
chr2_-_9695827 6.399 ADAM17
ADAM metallopeptidase domain 17
chr17_+_42219382 6.379 C17orf53
chromosome 17 open reading frame 53
chr4_+_72052354 6.292 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr19_+_4969123 6.284 NM_015015
KDM4B
lysine (K)-specific demethylase 4B
chr6_-_133084585 6.183 NM_078488
VNN2
vanin 2
chr1_-_40105296 6.158 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr19_-_16653202 6.153 CHERP
calcium homeostasis endoplasmic reticulum protein
chr10_+_47746919 6.147 NM_001630
ANXA8L2
ANXA8
annexin A8-like 2
annexin A8
chr5_-_95297597 6.114 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr1_-_38512446 6.104 NM_002699
POU3F1
POU class 3 homeobox 1
chr1_-_182573393 6.075 NM_002928
RGS16
regulator of G-protein signaling 16
chr8_+_23104120 6.053 CHMP7
charged multivesicular body protein 7
chr17_+_42219300 6.053 C17orf53
chromosome 17 open reading frame 53
chr17_+_7531275 6.009 SHBG
sex hormone-binding globulin
chr17_-_39743085 5.987 NM_000526
KRT14
keratin 14
chr3_+_4535160 5.980 ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr19_-_40919270 5.968 NM_020956
NM_181882
PRX

periaxin

chr16_-_31483425 5.945


chr16_-_3109335 5.943 LOC100507419
uncharacterized LOC100507419
chr19_-_58874078 5.929 NM_001207009
NM_198458
ZNF497

zinc finger protein 497

chr22_-_18484183 5.903 MICAL3
microtubule associated monoxygenase, calponin and LIM domain containing 3
chr17_+_26850958 5.902 NM_003593
FOXN1
forkhead box N1
chr10_+_8096772 5.902 GATA3
GATA binding protein 3
chr12_+_10365415 5.900 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr19_+_10541334 5.875 NM_001111308
PDE4A
phosphodiesterase 4A, cAMP-specific
chr11_+_117049838 5.871 NM_001040455
SIDT2
SID1 transmembrane family, member 2
chr3_+_16926451 5.854 NM_001144382
PLCL2
phospholipase C-like 2
chr19_-_49176263 5.811 NM_145807
NTN5
netrin 5
chr20_-_49253425 5.810 NM_080829
FAM65C
family with sequence similarity 65, member C
chr8_+_27183047 5.808 PTK2B
PTK2B protein tyrosine kinase 2 beta
chr19_-_41859767 5.805 TGFB1
transforming growth factor, beta 1
chr3_-_179169330 5.803 NM_021629
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr12_-_53448167 5.801 LOC283335
uncharacterized LOC283335
chr10_+_8097350 5.781 GATA3
GATA binding protein 3
chr8_-_101322180 5.769 RNF19A
ring finger protein 19A
chr16_+_2587951 5.755 NM_002613
NM_031268
PDPK1

3-phosphoinositide dependent protein kinase-1

chr1_-_157108169 5.754 NM_005240
NM_001145312
ETV3

ets variant 3

chr7_-_150498362 5.707 NM_014020
TMEM176B
transmembrane protein 176B
chr19_+_37407230 5.703 NM_001204835
NM_001204836
NM_001204837
NM_001204838
NM_001204839
NM_198539
ZNF568





zinc finger protein 568





chr7_+_73624086 5.696 NM_014146
NM_032463
NM_032464
LAT2


linker for activation of T cells family, member 2


chr5_+_161275541 5.691 NM_001127645
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr12_-_53613883 5.680 RARG
retinoic acid receptor, gamma

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.25 3.21e-22 GO:0065007 biological regulation
1.25 5.53e-19 GO:0050789 regulation of biological process
1.25 1.28e-17 GO:0050794 regulation of cellular process
1.37 2.51e-15 GO:0032502 developmental process
1.42 7.50e-15 GO:0048856 anatomical structure development
1.43 1.59e-13 GO:0048731 system development
1.38 1.60e-13 GO:0007275 multicellular organismal development
1.35 1.16e-12 GO:0023052 signaling
1.53 2.22e-12 GO:0048583 regulation of response to stimulus
1.57 4.32e-11 GO:0009653 anatomical structure morphogenesis
1.23 4.49e-11 GO:0050896 response to stimulus
1.12 7.97e-11 GO:0009987 cellular process
1.24 1.95e-09 GO:0032501 multicellular organismal process
1.37 3.16e-09 GO:0048518 positive regulation of biological process
1.41 4.78e-09 GO:0042221 response to chemical stimulus
1.49 7.17e-09 GO:0023051 regulation of signaling
1.42 8.58e-09 GO:0048869 cellular developmental process
1.27 1.47e-08 GO:0051716 cellular response to stimulus
1.65 1.68e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.31 2.14e-08 GO:0007165 signal transduction
1.27 3.95e-08 GO:0019222 regulation of metabolic process
1.29 5.07e-08 GO:0031323 regulation of cellular metabolic process
1.43 6.86e-08 GO:0048513 organ development
1.77 8.48e-08 GO:0010628 positive regulation of gene expression
1.50 1.25e-07 GO:0009966 regulation of signal transduction
1.49 1.26e-07 GO:0007399 nervous system development
1.40 1.37e-07 GO:0030154 cell differentiation
1.29 1.70e-07 GO:0080090 regulation of primary metabolic process
1.60 3.49e-07 GO:0009605 response to external stimulus
1.38 3.90e-07 GO:0006355 regulation of transcription, DNA-dependent
1.88 7.37e-07 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.76 1.03e-06 GO:0045893 positive regulation of transcription, DNA-dependent
1.33 1.12e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.28 1.34e-06 GO:0060255 regulation of macromolecule metabolic process
1.33 1.77e-06 GO:0010468 regulation of gene expression
1.34 2.22e-06 GO:0048522 positive regulation of cellular process
1.90 2.42e-06 GO:0032583 regulation of gene-specific transcription
1.32 2.48e-06 GO:0031326 regulation of cellular biosynthetic process
1.54 2.67e-06 GO:0010646 regulation of cell communication
1.35 2.71e-06 GO:0051252 regulation of RNA metabolic process
1.31 3.20e-06 GO:0009889 regulation of biosynthetic process
1.31 5.10e-06 GO:0051171 regulation of nitrogen compound metabolic process
1.48 6.11e-06 GO:0051239 regulation of multicellular organismal process
1.67 7.56e-06 GO:0002682 regulation of immune system process
1.71 1.50e-05 GO:0009887 organ morphogenesis
1.32 1.88e-05 GO:0006950 response to stress
1.32 1.92e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.66 2.20e-05 GO:0051254 positive regulation of RNA metabolic process
1.55 2.56e-05 GO:0050793 regulation of developmental process
1.31 2.67e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.76 3.09e-05 GO:0006935 chemotaxis
1.76 3.09e-05 GO:0042330 taxis
1.33 4.18e-05 GO:0065008 regulation of biological quality
1.94 5.52e-05 GO:0045597 positive regulation of cell differentiation
1.31 5.67e-05 GO:0048519 negative regulation of biological process
1.33 7.42e-05 GO:0048523 negative regulation of cellular process
1.54 7.69e-05 GO:0009611 response to wounding
1.55 9.24e-05 GO:0040011 locomotion
1.87 9.97e-05 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.78 1.01e-04 GO:0051094 positive regulation of developmental process
2.14 1.73e-04 GO:0043193 positive regulation of gene-specific transcription
1.79 2.27e-04 GO:0007409 axonogenesis
1.43 3.03e-04 GO:0002376 immune system process
1.56 3.22e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.55 3.52e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.57 3.60e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.53 4.87e-04 GO:0048584 positive regulation of response to stimulus
1.74 5.63e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.33 8.20e-04 GO:0007166 cell surface receptor linked signaling pathway
1.91 9.18e-04 GO:0051270 regulation of cellular component movement
1.40 1.04e-03 GO:0009893 positive regulation of metabolic process
1.67 1.13e-03 GO:0048858 cell projection morphogenesis
1.53 1.17e-03 GO:0007267 cell-cell signaling
1.84 1.21e-03 GO:0007411 axon guidance
1.71 1.23e-03 GO:0048812 neuron projection morphogenesis
1.42 1.49e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.66 1.70e-03 GO:0032990 cell part morphogenesis
1.45 1.77e-03 GO:0007154 cell communication
1.89 1.81e-03 GO:0040012 regulation of locomotion
1.67 1.85e-03 GO:0031175 neuron projection development
1.60 1.90e-03 GO:0000902 cell morphogenesis
1.69 2.33e-03 GO:0050776 regulation of immune response
1.45 2.63e-03 GO:0032879 regulation of localization
1.52 3.13e-03 GO:2000026 regulation of multicellular organismal development
1.65 3.51e-03 GO:0019226 transmission of nerve impulse
1.65 3.51e-03 GO:0035637 multicellular organismal signaling
1.52 3.81e-03 GO:0006468 protein phosphorylation
1.48 4.00e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.53 4.26e-03 GO:0030182 neuron differentiation
1.56 4.29e-03 GO:0032989 cellular component morphogenesis
1.63 5.70e-03 GO:0000904 cell morphogenesis involved in differentiation
1.37 5.88e-03 GO:0010033 response to organic substance
1.47 6.26e-03 GO:0009891 positive regulation of biosynthetic process
1.46 6.41e-03 GO:0006351 transcription, DNA-dependent
1.88 6.75e-03 GO:0030334 regulation of cell migration
2.15 6.83e-03 GO:0040017 positive regulation of locomotion
1.62 6.89e-03 GO:0048585 negative regulation of response to stimulus
1.54 8.42e-03 GO:0030030 cell projection organization
1.86 1.01e-02 GO:2000145 regulation of cell motility
1.57 1.08e-02 GO:0048666 neuron development
1.65 1.09e-02 GO:0002684 positive regulation of immune system process
1.60 1.21e-02 GO:0007417 central nervous system development
1.43 1.30e-02 GO:0048468 cell development
1.33 1.32e-02 GO:0065009 regulation of molecular function
1.55 1.36e-02 GO:0042060 wound healing
2.10 1.37e-02 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
1.37 1.47e-02 GO:0031325 positive regulation of cellular metabolic process
1.64 1.60e-02 GO:0007268 synaptic transmission
2.09 1.62e-02 GO:0051272 positive regulation of cellular component movement
1.57 1.77e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.49 1.94e-02 GO:0019220 regulation of phosphate metabolic process
1.49 1.94e-02 GO:0051174 regulation of phosphorus metabolic process
2.11 1.98e-02 GO:0030335 positive regulation of cell migration
2.11 1.98e-02 GO:2000147 positive regulation of cell motility
1.50 1.99e-02 GO:0009719 response to endogenous stimulus
1.42 2.06e-02 GO:0022008 neurogenesis
1.44 2.32e-02 GO:0048699 generation of neurons
2.53 2.33e-02 GO:0045637 regulation of myeloid cell differentiation
1.56 2.37e-02 GO:0051253 negative regulation of RNA metabolic process
1.57 2.94e-02 GO:0080134 regulation of response to stress
1.52 3.08e-02 GO:0010629 negative regulation of gene expression
1.49 3.14e-02 GO:0045595 regulation of cell differentiation
1.74 3.18e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.64 4.30e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.57 4.33e-02 GO:0007596 blood coagulation
1.57 4.33e-02 GO:0050817 coagulation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.37 6.98e-08 GO:0044459 plasma membrane part
1.44 6.51e-05 GO:0000267 cell fraction
1.41 7.35e-05 GO:0005887 integral to plasma membrane
1.40 1.21e-04 GO:0031226 intrinsic to plasma membrane
1.43 3.60e-03 GO:0005626 insoluble fraction
1.43 4.36e-03 GO:0005624 membrane fraction
1.61 1.19e-02 GO:0009986 cell surface

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 2.23e-12 GO:0005488 binding
1.19 4.85e-12 GO:0005515 protein binding
1.74 2.98e-08 GO:0043565 sequence-specific DNA binding
1.58 1.27e-07 GO:0001071 nucleic acid binding transcription factor activity
1.58 1.27e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.55 5.28e-07 GO:0030528 transcription regulator activity
1.96 6.02e-06 GO:0016563 transcription activator activity
1.94 1.74e-04 GO:0032403 protein complex binding
1.85 4.63e-04 GO:0008134 transcription factor binding
1.42 8.42e-04 GO:0005102 receptor binding
1.26 1.57e-03 GO:0003677 DNA binding
1.74 8.10e-03 GO:0005083 small GTPase regulator activity
1.92 8.16e-03 GO:0010843 promoter binding
1.89 1.09e-02 GO:0000975 regulatory region DNA binding
1.89 1.09e-02 GO:0001067 regulatory region nucleic acid binding
1.89 1.09e-02 GO:0044212 transcription regulatory region DNA binding
1.76 1.26e-02 GO:0005261 cation channel activity
1.55 2.24e-02 GO:0030695 GTPase regulator activity
1.53 3.47e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.36 4.55e-02 GO:0030234 enzyme regulator activity