Motif ID: GUAACAG

Z-value: 0.838


Mature miRNA associated with seed GUAACAG:

NamemiRBase Accession
hsa-miR-194 MIMAT0000460



Activity profile for motif GUAACAG.

activity profile for motif GUAACAG


Sorted Z-values histogram for motif GUAACAG

Sorted Z-values for motif GUAACAG



Network of associatons between targets according to the STRING database.



First level regulatory network of GUAACAG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_119738542 19.417 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chrX_+_119737743 18.530 NM_014060
MCTS1
malignant T cell amplified sequence 1
chr3_-_195808958 17.705 NM_003234
TFRC
transferrin receptor (p90, CD71)
chr3_-_195808997 17.461 NM_001128148
TFRC
transferrin receptor (p90, CD71)
chr3_+_180630054 16.024 NM_001013438
NM_001013439
NM_005087
FXR1


fragile X mental retardation, autosomal homolog 1


chr12_-_54653317 15.451 NM_001127322
CBX5
chromobox homolog 5
chr12_-_54653369 14.641 NM_001127321
CBX5
chromobox homolog 5
chr3_-_113465101 12.918 NM_025146
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr2_+_85198176 12.480 NM_020122
KCMF1
potassium channel modulatory factor 1
chr9_+_131445933 12.117 NM_001122821
SET
SET nuclear oncogene
chr5_+_72112417 11.930 NM_002270
TNPO1
transportin 1
chr1_+_33116748 11.719 NM_001135255
NM_005610
NM_001135256
RBBP4


retinoblastoma binding protein 4


chr3_+_152880024 11.649 NM_002886
RAP2B
RAP2B, member of RAS oncogene family
chr2_-_230786618 11.394 NM_004238
TRIP12
thyroid hormone receptor interactor 12
chr11_+_74660290 11.181 NM_014752
LOC653566
SPCS2
signal peptidase complex subunit 2 homolog pseudogene
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr16_-_87903028 10.531 NM_003486
SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr7_+_77167351 10.090 NM_001131008
NM_001131009
PTPN12

protein tyrosine phosphatase, non-receptor type 12

chr5_+_72143929 9.882 NM_153188
TNPO1
transportin 1
chr5_-_98262217 9.670 NM_001270
CHD1
chromodomain helicase DNA binding protein 1
chr2_-_174828775 9.463 NM_001017371
SP3
Sp3 transcription factor
chr5_+_177019196 9.218 NM_017510
TMED9
transmembrane emp24 protein transport domain containing 9
chr3_-_185655833 9.161 NM_001243879
NM_004593
TRA2B

transformer 2 beta homolog (Drosophila)

chr1_-_225840660 8.876 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr16_-_58768132 8.850 NM_002080
GOT2
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
chr1_-_93646245 8.257 NM_001167830
NM_016040
TMED5

transmembrane emp24 protein transport domain containing 5

chr12_-_76425375 8.244 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr9_+_131451470 8.182 NM_003011
SET
SET nuclear oncogene
chr6_+_163835668 8.148 NM_006775
NM_206853
NM_206854
NM_206855
QKI



QKI, KH domain containing, RNA binding



chr1_-_212965104 8.061 NM_001042549
NM_015471
NSL1

NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)

chr2_+_238600780 7.955 NM_001137551
NM_001137552
NM_001137553
NM_004735
LRRFIP1



leucine rich repeat (in FLII) interacting protein 1



chr12_-_29534089 7.624 NM_016570
ERGIC2
ERGIC and golgi 2
chrX_+_49832214 7.588 NM_000084
CLCN5
chloride channel 5
chr15_-_59225800 7.403 NM_001013843
NM_024755
SLTM

SAFB-like, transcription modulator

chr15_+_96869156 7.036 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr21_-_16437125 6.811 NM_003489
NRIP1
nuclear receptor interacting protein 1
chr3_+_69812620 6.566 NM_001184967
MITF
microphthalmia-associated transcription factor
chr4_-_24586178 6.468 NM_001358
DHX15
DEAH (Asp-Glu-Ala-His) box polypeptide 15
chr11_-_46142955 6.458 NM_001101802
NM_016621
PHF21A

PHD finger protein 21A

chr16_-_12010518 6.413 NM_001130007
GSPT1
G1 to S phase transition 1
chr2_-_174830429 6.361 NM_001172712
NM_003111
SP3

Sp3 transcription factor

chr15_+_99192696 6.125 NM_000875
IGF1R
insulin-like growth factor 1 receptor
chr3_+_148709140 6.099 NM_001184720
NM_001184721
NM_004130
GYG1


glycogenin 1


chr3_+_69812961 6.040 NM_006722
MITF
microphthalmia-associated transcription factor
chr2_+_102314162 5.985 NM_001242560
NM_004834
NM_145686
NM_001242559
NM_145687
MAP4K4




mitogen-activated protein kinase kinase kinase kinase 4




chr15_-_37391596 5.905 NM_172316
MEIS2
Meis homeobox 2
chr1_-_202777545 5.847 NM_006618
KDM5B
lysine (K)-specific demethylase 5B
chr10_+_114709963 5.782 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr8_+_104311058 5.682 NM_001164616
NM_003506
FZD6

frizzled family receptor 6

chr8_+_104310660 5.669 NM_001164615
FZD6
frizzled family receptor 6
chr2_-_158731622 5.649 NM_001105
ACVR1
activin A receptor, type I
chr15_-_59981517 5.586 NM_004330
BNIP2
BCL2/adenovirus E1B 19kDa interacting protein 2
chr1_-_52456292 5.447 NM_002867
RAB3B
RAB3B, member RAS oncogene family
chr7_+_77166750 5.416 NM_002835
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr7_-_94285477 5.380 NM_001099400
NM_001099401
NM_003919
SGCE


sarcoglycan, epsilon


chr6_+_20402040 5.354 NM_001949
E2F3
E2F transcription factor 3
chr17_-_73179093 5.258 NM_001005849
NM_006937
SUMO2

SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)

chr17_-_47439326 5.237 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr8_-_28243941 5.084 NM_018660
ZNF395
zinc finger protein 395
chr4_+_77870864 4.940 NM_018243
SEPT11
septin 11
chr16_-_12009804 4.861 NM_001130006
NM_002094
GSPT1

G1 to S phase transition 1

chr3_+_69788562 4.835 NM_198159
MITF
microphthalmia-associated transcription factor
chr9_+_117349993 4.751 NM_004888
ATP6V1G1
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr15_-_37390372 4.593 NM_172315
MEIS2
Meis homeobox 2
chr17_+_48796919 4.428 NM_006107
NM_016424
LUC7L3

LUC7-like 3 (S. cerevisiae)

chr1_+_27248212 4.411 NM_006600
NUDC
nuclear distribution gene C homolog (A. nidulans)
chr1_-_205719340 4.345 NM_022731
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr10_-_65028825 4.299 NM_004241
JMJD1C
jumonji domain containing 1C
chr12_+_69004614 4.283 NM_001010942
NM_001251917
NM_001251918
NM_001251921
NM_001251922
NM_015646
RAP1B





RAP1B, member of RAS oncogene family





chr11_-_10830581 4.234 NM_001042559
NM_001418
EIF4G2

eukaryotic translation initiation factor 4 gamma, 2

chr18_+_3453771 4.225 NM_173211
TGIF1
TGFB-induced factor homeobox 1
chr3_+_69915374 4.212 NM_198177
MITF
microphthalmia-associated transcription factor
chr2_+_86426555 4.187 NM_016622
NM_145644
MRPL35

mitochondrial ribosomal protein L35

chr18_+_3412071 4.147 NM_174886
TGIF1
TGFB-induced factor homeobox 1
chr18_+_3447607 4.143 NM_173207
TGIF1
TGFB-induced factor homeobox 1
chr18_+_3449972 4.136 NM_173209
NM_173208
NM_003244
TGIF1


TGFB-induced factor homeobox 1


chr14_-_38064440 4.127 NM_004496
FOXA1
forkhead box A1
chr20_-_43977023 4.041 NM_002999
SDC4
syndecan 4
chr17_+_66508525 3.978 NM_002734
NM_212472
PRKAR1A

protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)

chr1_-_153958688 3.847 NM_002870
RAB13
RAB13, member RAS oncogene family
chr3_+_37903643 3.816 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr18_+_3451589 3.780 NM_170695
NM_173210
TGIF1

TGFB-induced factor homeobox 1

chr12_+_124069053 3.737 NM_006815
TMED2
transmembrane emp24 domain trafficking protein 2
chrX_+_38663072 3.723 NM_021242
MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr10_-_88281515 3.654 NM_015045
WAPAL
wings apart-like homolog (Drosophila)
chr9_-_123555654 3.628 NM_012164
FBXW2
F-box and WD repeat domain containing 2
chr20_-_34330179 3.529 NM_001242599
NM_001242600
NM_004902
NM_184234
RBM39



RNA binding motif protein 39



chr16_-_73092533 3.524 NM_001164766
ZFHX3
zinc finger homeobox 3
chr6_-_7910716 3.521 NM_030810
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr5_+_176560056 3.509 NM_172349
NSD1
nuclear receptor binding SET domain protein 1
chr17_+_45727274 3.361 NM_002265
KPNB1
karyopherin (importin) beta 1
chr4_-_76912052 3.355 NM_018115
SDAD1
SDA1 domain containing 1
chr15_+_77713229 3.330 NM_018200
HMG20A
high mobility group 20A
chr9_-_74979829 3.181 NM_001102420
NM_001102421
NM_006007
ZFAND5


zinc finger, AN1-type domain 5


chrX_-_119709618 3.144 NM_003588
CUL4B
cullin 4B
chr15_+_96876568 3.139 NM_001145157
NR2F2
nuclear receptor subfamily 2, group F, member 2
chrX_+_38660653 3.134 NM_001098790
NM_001098791
MID1IP1

MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))

chr14_+_32546445 3.116 NM_001030055
NM_001173
ARHGAP5

Rho GTPase activating protein 5

chrX_-_119694719 3.114 NM_001079872
CUL4B
cullin 4B
chr6_-_111804413 3.072 NM_002912
REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr8_-_131455833 3.067 NM_001247996
NM_018482
ASAP1

ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

chr15_-_37393364 3.057 NM_001220482
NM_002399
MEIS2

Meis homeobox 2

chr16_+_53088791 3.013 NM_025134
CHD9
chromodomain helicase DNA binding protein 9
chr16_-_73082169 2.987 NM_006885
ZFHX3
zinc finger homeobox 3
chr20_-_524335 2.963 NM_001895
NM_177559
NM_177560
CSNK2A1


casein kinase 2, alpha 1 polypeptide


chr6_-_83903632 2.846 NM_001199917
PGM3
phosphoglucomutase 3
chr8_+_48920969 2.812 NM_003350
UBE2V2
ubiquitin-conjugating enzyme E2 variant 2
chr7_+_141251077 2.771 NM_018238
AGK
acylglycerol kinase
chr14_-_21899866 2.746 NM_001170629
CHD8
chromodomain helicase DNA binding protein 8
chr5_-_88119604 2.728 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr6_-_7910278 2.649 NM_001145549
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr10_-_65225605 2.645 NM_032776
JMJD1C
jumonji domain containing 1C
chr20_-_61847446 2.632 NM_017798
YTHDF1
YTH domain family, member 1
chr4_-_140060601 2.610 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chr3_-_149688638 2.592 NM_002628
NM_053024
PFN2

profilin 2

chr3_+_196466724 2.588 NM_002577
PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr22_+_41347328 2.580 NM_014248
RBX1
ring-box 1, E3 ubiquitin protein ligase
chr6_+_43457214 2.575 NM_001146017
TJAP1
tight junction associated protein 1 (peripheral)
chr12_-_76953561 2.562 NM_001003712
NM_020841
OSBPL8

oxysterol binding protein-like 8

chr1_-_94703252 2.551 NM_004815
ARHGAP29
Rho GTPase activating protein 29
chr1_+_93811476 2.448 NM_001938
DR1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr1_+_2985730 2.366 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr17_+_66508098 2.292 NM_212471
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr10_-_13390189 2.279 NM_001195602
NM_001195604
NM_012247
SEPHS1


selenophosphate synthetase 1


chr9_-_124984018 2.260 NM_001242335
LHX6
LIM homeobox 6
chr5_+_176873795 2.248 NM_001174101
NM_030567
PRR7

proline rich 7 (synaptic)

chr17_+_27071008 2.212 NM_004295
TRAF4
TNF receptor-associated factor 4
chr12_-_54673901 2.201 NM_012117
CBX5
chromobox homolog 5
chr22_-_30642683 2.169 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr1_-_25256767 2.165 NM_004350
RUNX3
runt-related transcription factor 3
chr17_+_2496902 2.148 NM_000430
PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr3_+_69985750 2.037 NM_000248
NM_001184968
NM_198158
NM_198178
MITF



microphthalmia-associated transcription factor



chr12_+_93771607 2.033 NM_019094
NM_199040
NUDT4

NUDT4P1
nudix (nucleoside diphosphate linked moiety X)-type motif 4

nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1
chr15_+_64388082 2.032 NM_001242933
NM_003099
NM_148955
SNX1


sorting nexin 1


chr2_-_158732341 2.019 NM_001111067
ACVR1
activin A receptor, type I
chr19_+_34919213 1.973 NM_005499
UBA2
ubiquitin-like modifier activating enzyme 2
chr18_+_9913954 1.958 NM_003574
NM_194434
VAPA

VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa

chr17_-_65241305 1.930 NM_014877
HELZ
helicase with zinc finger
chr17_-_30669133 1.887 NM_022344
C17orf75
chromosome 17 open reading frame 75
chr16_+_30675777 1.842 NM_001105079
FBRS
fibrosin
chr1_-_206945725 1.824 NM_000572
IL10
interleukin 10
chr17_+_40985416 1.817 NM_005789
NM_176863
PSME3

proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)

chr5_-_59783885 1.786 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_+_152266603 1.763 NM_001177665
RIF1
RAP1 interacting factor homolog (yeast)
chr12_+_56915587 1.741 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr2_+_152266384 1.722 NM_001177663
NM_018151
NM_001177664
RIF1


RAP1 interacting factor homolog (yeast)


chr12_-_25055966 1.709 NM_001178093
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr15_-_37392358 1.687 NM_170674
NM_170675
NM_170676
NM_170677
MEIS2



Meis homeobox 2



chr14_-_68066919 1.663 NM_004569
PIGH
phosphatidylinositol glycan anchor biosynthesis, class H
chr14_-_21737506 1.654 NM_001077442
NM_001077443
NM_004500
NM_031314
HNRNPC



heterogeneous nuclear ribonucleoprotein C (C1/C2)



chr4_+_184020343 1.610 NM_024949
WWC2
WW and C2 domain containing 2
chr2_-_122406994 1.586 NM_001142273
NM_001142274
NM_001207051
NM_015282
CLASP1



cytoplasmic linker associated protein 1



chr12_+_93963597 1.583 NM_003877
SOCS2
suppressor of cytokine signaling 2
chr9_-_95527002 1.570 NM_001003800
NM_015250
BICD2

bicaudal D homolog 2 (Drosophila)

chr1_+_36348795 1.538 NM_012199
EIF2C1
eukaryotic translation initiation factor 2C, 1
chr17_-_8534008 1.472 NM_005964
MYH10
myosin, heavy chain 10, non-muscle
chr16_+_47495166 1.442 NM_000293
NM_001031835
PHKB

phosphorylase kinase, beta

chr9_-_8733893 1.435 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr17_+_37617688 1.432 NM_015083
NM_016507
CDK12

cyclin-dependent kinase 12

chr5_-_139726173 1.432 NM_001945
HBEGF
heparin-binding EGF-like growth factor
chr12_-_24102563 1.411 NM_006940
SOX5
SRY (sex determining region Y)-box 5
chr8_-_116681103 1.406 NM_014112
TRPS1
trichorhinophalangeal syndrome I
chr1_-_25291474 1.400 NM_001031680
RUNX3
runt-related transcription factor 3
chr5_+_176875325 1.395 NM_001174102
PRR7
proline rich 7 (synaptic)
chr14_-_21905401 1.366 NM_020920
CHD8
chromodomain helicase DNA binding protein 8
chr4_-_23891608 1.319 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr15_+_96875793 1.316 NM_001145156
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr20_+_57226287 1.315 NM_001001433
NM_001134772
NM_001134773
NM_001204868
NM_003763
STX16-NPEPL1
STX16




STX16-NPEPL1 readthrough (non-protein coding)
syntaxin 16




chrX_-_71933709 1.264 NM_001122670
NM_001172436
NM_002637
PHKA1


phosphorylase kinase, alpha 1 (muscle)


chr12_-_25055228 1.229 NM_001178094
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr5_-_74807448 1.140 NM_005713
NM_031361
COL4A3BP

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr3_-_125314367 1.098 NM_022776
OSBPL11
oxysterol binding protein-like 11
chr6_-_43027114 1.086 NM_015950
MRPL2
mitochondrial ribosomal protein L2
chr17_-_36105005 1.069 NM_000458
NM_001165923
HNF1B

HNF1 homeobox B

chr9_-_139377503 0.993 NM_014866
SEC16A
SEC16 homolog A (S. cerevisiae)
chr7_-_559479 0.977 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr1_-_214724974 0.972 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr17_-_1359410 0.968 NM_005206
NM_016823
CRK

v-crk sarcoma virus CT10 oncogene homolog (avian)

chr2_-_128100673 0.937 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr1_+_179923870 0.902 NM_014810
CEP350
centrosomal protein 350kDa
chr17_-_80231560 0.877 NM_001893
NM_139062
CSNK1D

casein kinase 1, delta

chr11_+_74303626 0.876 NM_006591
POLD3
polymerase (DNA-directed), delta 3, accessory subunit
chr1_+_236681513 0.858 NM_201545
LGALS8
lectin, galactoside-binding, soluble, 8
chr7_-_72993007 0.847 NM_012453
TBL2
transducin (beta)-like 2
chr5_-_74807805 0.844 NM_001130105
COL4A3BP
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr7_+_145813452 0.842 NM_014141
CNTNAP2
contactin associated protein-like 2
chr15_-_30114536 0.839 NM_003257
NM_175610
TJP1

tight junction protein 1 (zona occludens 1)

chr12_-_25102281 0.839 NM_001178091
NM_001178092
NM_005504
BCAT1


branched chain amino-acid transaminase 1, cytosolic


chr10_+_124768401 0.831 NM_001609
ACADSB
acyl-CoA dehydrogenase, short/branched chain
chr12_-_102872329 0.809 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chr5_+_127419407 0.761 NM_001046
SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr2_-_208634051 0.752 NM_003468
FZD5
frizzled family receptor 5
chr6_+_33378772 0.751 NM_002636
NM_024165
PHF1

PHD finger protein 1

chrX_-_41782230 0.740 NM_001126054
NM_001126055
NM_003688
CASK


calcium/calmodulin-dependent serine protein kinase (MAGUK family)


chr15_+_96873845 0.734 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr12_+_102271082 0.721 NM_018370
DRAM1
DNA-damage regulated autophagy modulator 1
chr14_-_57735614 0.718 NM_006544
EXOC5
exocyst complex component 5
chr10_-_32217762 0.704 NM_018287
ARHGAP12
Rho GTPase activating protein 12
chr10_+_97889467 0.688 NM_014803
ZNF518A
zinc finger protein 518A
chr20_-_56285576 0.665 NM_199169
NM_199170
PMEPA1

prostate transmembrane protein, androgen induced 1

chr18_-_29523087 0.655 NM_014939
TRAPPC8
trafficking protein particle complex 8

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.35 1.35e-08 GO:0009987 cellular process
1.92 1.44e-08 GO:0044260 cellular macromolecule metabolic process
2.06 3.86e-08 GO:0080090 regulation of primary metabolic process
2.03 7.75e-08 GO:0031323 regulation of cellular metabolic process
2.06 1.73e-07 GO:0060255 regulation of macromolecule metabolic process
1.89 1.39e-06 GO:0019222 regulation of metabolic process
3.23 1.52e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.24 1.84e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.55 2.76e-06 GO:0050794 regulation of cellular process
2.30 4.81e-06 GO:0048523 negative regulation of cellular process
2.18 4.98e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.72 5.50e-06 GO:0043170 macromolecule metabolic process
1.58 1.19e-05 GO:0044237 cellular metabolic process
3.54 2.78e-05 GO:0031327 negative regulation of cellular biosynthetic process
2.06 2.81e-05 GO:0031326 regulation of cellular biosynthetic process
2.14 4.20e-05 GO:0048519 negative regulation of biological process
3.47 4.23e-05 GO:0009890 negative regulation of biosynthetic process
2.04 4.23e-05 GO:0009889 regulation of biosynthetic process
3.55 5.07e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
1.48 5.90e-05 GO:0050789 regulation of biological process
2.03 7.17e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.16 8.28e-05 GO:0090304 nucleic acid metabolic process
2.00 8.35e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.44 8.88e-05 GO:0065007 biological regulation
3.56 8.92e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.14 1.50e-04 GO:0006355 regulation of transcription, DNA-dependent
2.99 1.58e-04 GO:0031324 negative regulation of cellular metabolic process
2.01 2.49e-04 GO:0010468 regulation of gene expression
3.44 3.19e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
3.62 4.64e-04 GO:0045892 negative regulation of transcription, DNA-dependent
2.06 4.87e-04 GO:0051252 regulation of RNA metabolic process
1.94 4.87e-04 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.27 5.95e-04 GO:0009059 macromolecule biosynthetic process
3.55 6.47e-04 GO:0051253 negative regulation of RNA metabolic process
2.86 6.74e-04 GO:0010605 negative regulation of macromolecule metabolic process
2.51 7.16e-04 GO:0009893 positive regulation of metabolic process
1.50 7.60e-04 GO:0044238 primary metabolic process
3.38 7.90e-04 GO:0010629 negative regulation of gene expression
2.19 8.51e-04 GO:0006464 protein modification process
2.58 9.40e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.83 9.82e-04 GO:0034641 cellular nitrogen compound metabolic process
2.74 9.82e-04 GO:0009892 negative regulation of metabolic process
3.33 1.01e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.24 1.17e-03 GO:0034645 cellular macromolecule biosynthetic process
2.21 1.17e-03 GO:0016070 RNA metabolic process
2.51 1.74e-03 GO:0031325 positive regulation of cellular metabolic process
2.64 2.00e-03 GO:0032268 regulation of cellular protein metabolic process
2.57 2.27e-03 GO:0051246 regulation of protein metabolic process
1.77 3.12e-03 GO:0006807 nitrogen compound metabolic process
2.07 3.42e-03 GO:0043412 macromolecule modification
2.76 3.42e-03 GO:0006351 transcription, DNA-dependent
2.80 6.71e-03 GO:0031399 regulation of protein modification process
2.87 7.09e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.40 7.30e-03 GO:0008152 metabolic process
2.66 1.55e-02 GO:0031328 positive regulation of cellular biosynthetic process
2.98 1.70e-02 GO:0045893 positive regulation of transcription, DNA-dependent
4.20 1.78e-02 GO:0061061 muscle structure development
50.16 1.96e-02 GO:0007097 nuclear migration
3.32 1.99e-02 GO:0006325 chromatin organization
2.61 2.05e-02 GO:0009891 positive regulation of biosynthetic process
2.49 2.13e-02 GO:0032774 RNA biosynthetic process
1.84 2.20e-02 GO:0048522 positive regulation of cellular process
2.69 2.99e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4.60 3.55e-02 GO:0006916 anti-apoptosis
1.76 3.61e-02 GO:0048518 positive regulation of biological process
4.58 3.71e-02 GO:0043193 positive regulation of gene-specific transcription
7.81 3.75e-02 GO:0030522 intracellular receptor mediated signaling pathway
3.45 4.04e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.79 4.29e-02 GO:0044267 cellular protein metabolic process
2.78 4.63e-02 GO:0051254 positive regulation of RNA metabolic process
2.61 4.71e-02 GO:0051173 positive regulation of nitrogen compound metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.31 8.29e-09 GO:0005622 intracellular
1.31 4.12e-08 GO:0044424 intracellular part
2.46 8.89e-05 GO:0005654 nucleoplasm
3.09 1.13e-04 GO:0044451 nucleoplasm part
1.51 5.34e-04 GO:0005634 nucleus
1.29 6.18e-04 GO:0043229 intracellular organelle
1.94 6.71e-04 GO:0043233 organelle lumen
1.29 7.02e-04 GO:0043226 organelle
2.08 7.30e-04 GO:0031981 nuclear lumen
1.90 1.06e-03 GO:0031974 membrane-enclosed lumen
12.87 1.22e-03 GO:0000118 histone deacetylase complex
1.93 1.64e-03 GO:0044428 nuclear part
1.89 2.02e-03 GO:0070013 intracellular organelle lumen
11.40 2.51e-03 GO:0017053 transcriptional repressor complex
1.31 2.89e-03 GO:0043231 intracellular membrane-bounded organelle
1.46 3.01e-03 GO:0044422 organelle part
1.31 3.09e-03 GO:0043227 membrane-bounded organelle
1.71 4.96e-03 GO:0043234 protein complex
1.45 5.69e-03 GO:0044446 intracellular organelle part
1.87 7.16e-03 GO:0005829 cytosol
1.29 2.42e-02 GO:0005737 cytoplasm
1.56 3.03e-02 GO:0032991 macromolecular complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.56 1.83e-08 GO:0005515 protein binding
1.23 1.02e-04 GO:0005488 binding
4.95 3.55e-03 GO:0003682 chromatin binding
6.76 5.77e-03 GO:0051427 hormone receptor binding
2.38 6.35e-03 GO:0030528 transcription regulator activity
2.34 1.13e-02 GO:0001071 nucleic acid binding transcription factor activity
2.34 1.13e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
3.17 1.21e-02 GO:0019904 protein domain specific binding
5.19 1.47e-02 GO:0003714 transcription corepressor activity
3.63 1.61e-02 GO:0016564 transcription repressor activity
6.73 1.92e-02 GO:0035257 nuclear hormone receptor binding
3.53 2.09e-02 GO:0016563 transcription activator activity
1.60 2.50e-02 GO:0003676 nucleic acid binding
27.87 3.12e-02 GO:0008139 nuclear localization sequence binding